Primary Site >> Liver Cancer

Gene >> E2F1

1.
Journal: Mol Carcinog. 1995 Sep;14(1):46-52.
Title: Strain-dependent differences in DNA synthesis and gene expression in the regenerating livers of CB57BL/6J and C3H/HeJ mice.
Author: Bennett, L M|Farnham, P J|Drinkwater, N R
PMID: 7546224
2.
Journal: Cancer Res. 1998 Jan 1;58(1):123-34.
Title: Disruption of the pRb/E2F pathway and inhibition of apoptosis are major oncogenic events in liver constitutively expressing c-myc and transforming growth factor alpha.
Author: Santoni-Rugiu, E|Jensen, M R|Thorgeirsson, S S
PMID: 9426068
3.
Journal: Mol Carcinog. 1999 Aug;25(4):295-303.
Title: No effect of loss of E2F1 on liver regeneration or hepatocarcinogenesis in C57BL/6J or C3H/HeJ mice.
Author: Lukas, E R|Bartley, S M|Graveel, C R|Diaz, Z M|Dyson, N|Harlow, E|Yamasaki, L|Farnham, P J
PMID: 10449036
4.
Journal: DNA Cell Biol. 2001 Feb;20(2):75-80.
Title: Hepatitis B viral X protein overcomes inhibition of E2F1 activity by pRb on the human Rb gene promoter.
Author: Choi, B H|Choi, M|Jeon, H Y|Rho, H M
PMID: 11244564
5.
Journal: Mol Cell Biol. 2001 Oct;21(20):6820-32.
Title: Use of chromatin immunoprecipitation to clone novel E2F target promoters.
Author: Weinmann, A S|Bartley, S M|Zhang, T|Zhang, M Q|Farnham, P J
PMID: 11564866
6.
Journal: Biochem Biophys Res Commun. 2003 Feb 28;302(1):114-20.
Title: E2F1 blocks and c-Myc accelerates hepatic ploidy in transgenic mouse models.
Author: Conner, Elizabeth A|Lemmer, Eric R|Sanchez, Aranzazu|Factor, Valentina M|Thorgeirsson, Snorri S
PMID: 12593856
7.
Journal: Biol Chem. 2003 Feb;384(2):203-12.
Title: Transcriptional repression of the human p53 gene by hepatitis B viral core protein (HBc) in human liver cells.
Author: Kwon, Jin Ah|Rho, Hyune Mo
PMID: 12675512
8.
Journal: J Hum Genet. 2003;48(12):609-13.
Title: Association of over-expressed TFDP1 with progression of hepatocellular carcinomas.
Author: Yasui, Kohichiroh|Okamoto, Hiroyuki|Arii, Shigeki|Inazawa, Johji
PMID: 14618416
9.
Journal: Carcinogenesis. 2004 Mar;25(3):333-41.
Title: Down-regulation of c-myc and Cyclin D1 genes by antisense oligodeoxy nucleotides inhibits the expression of E2F1 and in vitro growth of HepG2 and Morris 5123 liver cancer cells.
Author: Simile, Maria M|De Miglio, Maria R|Muroni, Maria R|Frau, Maddalena|Asara, Giuseppina|Serra, Silvia|Muntoni, Maria D|Seddaiu, Maria A|Daino, Lucia|Feo, Francesco|Pascale, Rosa M
PMID: 14604889
10.
Journal: Lab Invest. 2004 Sep;84(9):1137-47.
Title: Disregulation of E-cadherin in transgenic mouse models of liver cancer.
Author: Calvisi, Diego F|Ladu, Sara|Conner, Elizabeth A|Factor, Valentina M|Thorgeirsson, Snorri S
PMID: 15220935
11.
Journal: Biochem Biophys Res Commun. 2004 Sep 10;322(1):297-302.
Title: Transcription of dbpA, a Y box binding protein, is positively regulated by E2F1: implications in hepatocarcinogenesis.
Author: Arakawa, Yasuo|Kajino, Kazunori|Kano, Sayaka|Tobita, Hiroshi|Hayashi, Junpei|Yasen, Mahamute|Moriyama, Mitsuhiko|Arakawa, Yasuyuki|Hino, Okio
PMID: 15313206
12.
Journal: Nat Genet. 2004 Dec;36(12):1306-11.
Title: Application of comparative functional genomics to identify best-fit mouse models to study human cancer.
Author: Lee, Ju-Seog|Chu, In-Sun|Mikaelyan, Arsen|Calvisi, Diego F|Heo, Jeonghoon|Reddy, Janardan K|Thorgeirsson, Snorri S
PMID: 15565109
13.
Journal: J Hepatol. 2005 Jun;42(6):842-9.
Title: Activation of the canonical Wnt/beta-catenin pathway confers growth advantages in c-Myc/E2F1 transgenic mouse model of liver cancer.
Author: Calvisi, Diego F|Conner, Elizabeth A|Ladu, Sara|Lemmer, Eric R|Factor, Valentina M|Thorgeirsson, Snorri S
PMID: 15885355
14.
Journal: Clin Cancer Res. 2005 Nov 15;11(22):8213-21.
Title: In vitro and in vivo effects and mechanisms of celecoxib-induced growth inhibition of human hepatocellular carcinoma cells.
Author: Cui, Wei|Yu, Chang-Hong|Hu, Ke-Qin
PMID: 16299255
15.
Journal: Int J Oncol. 2006 Sep;29(3):673-9.
Title: Gene expression profile of DNA binding protein A transgenic mice.
Author: Tobita, Hiroshi|Kajino, Kazunori|Inami, Kouichi|Kano, Sayaka|Yasen, Mahmut|Imamura, Osamu|Kinoshita, Yoshikazu|Hino, Okio
PMID: 16865284
16.
Journal: Hepatology. 2006 Oct;44(4):1003-11.
Title: Oncogene-specific gene expression signatures at preneoplastic stage in mice define distinct mechanisms of hepatocarcinogenesis.
Author: Coulouarn, Cedric|Gomez-Quiroz, Luis E|Lee, Ju-Seog|Kaposi-Novak, Pal|Conner, Elizabeth A|Goldina, Tatyana A|Onishchenko, Galina E|Factor, Valentina M|Thorgeirsson, Snorri S
PMID: 17006931
17.
Journal: Cancer Res. 2007 Jun 15;67(12):5771-8.
Title: Expression of DNA methyltransferase 1 is activated by hepatitis B virus X protein via a regulatory circuit involving the p16INK4a-cyclin D1-CDK 4/6-pRb-E2F1 pathway.
Author: Jung, Jin Kyu|Arora, Payal|Pagano, Joseph S|Jang, Kyung Lib
PMID: 17575144
18.
Journal: World J Gastroenterol. 2007 Oct 28;13(40):5299-305.
Title: Effects and mechanisms of silibinin on human hepatoma cell lines.
Author: Lah, John-J|Cui, Wei|Hu, Ke-Qin
PMID: 17879397
19.
Journal: J Biol Chem. 2008 Sep 12;283(37):25455-67.
Title: Hepatitis B virus X protein via the p38MAPK pathway induces E2F1 release and ATR kinase activation mediating p53 apoptosis.
Author: Wang, Wen-Horng|Hullinger, Ronald L|Andrisani, Ourania M
PMID: 18606816
20.
Journal: Hepatol Res. 2008 Sep;38(9):886-95.
Title: Activation of B-Myb by E2F1 in hepatocellular carcinoma.
Author: Nakajima, Tomoaki|Yasui, Kohichiroh|Zen, Keika|Inagaki, Yoshikazu|Fujii, Hideki|Minami, Masahito|Tanaka, Shinji|Taniwaki, Masafumi|Itoh, Yoshito|Arii, Shigeki|Inazawa, Johji|Okanoue, Takeshi
PMID: 18624722
21.
Journal: Hepatology. 2008 Aug;48(2):617-23.
Title: Genetic control of resistance to hepatocarcinogenesis by the mouse Hpcr3 locus.
Author: Manenti, Giacomo|Galvan, Antonella|Falvella, F Stefania|Pascale, Rosa M|Spada, Elena|Milani, Silvano|Gonzalez Neira, Anna|Feo, Francesco|Dragani, Tommaso A
PMID: 18666244
22.
Journal: Gastroenterology. 2008 Oct;135(4):1322-32.
Title: E2F1 inhibits c-Myc-driven apoptosis via PIK3CA/Akt/mTOR and COX-2 in a mouse model of human liver cancer.
Author: Ladu, Sara|Calvisi, Diego F|Conner, Elizabeth A|Farina, Miriam|Factor, Valentina M|Thorgeirsson, Snorri S
PMID: 18722373
23.
Journal: Clin Cancer Res. 2008 Sep 1;14(17):5519-30.
Title: Experimental therapy of hepatoma with artemisinin and its derivatives: in vitro and in vivo activity, chemosensitization, and mechanisms of action.
Author: Hou, Junmei|Wang, Disong|Zhang, Ruiwen|Wang, Hui
PMID: 18765544
24.
Journal: Anticancer Drugs. 2008 Oct;19(9):891-7.
Title: In-vivo effects and mechanisms of celecoxib-reduced growth of cyclooxygenase-2 (COX-2)-expressing versus COX-2-deleted human HCC xenografts in nude mice.
Author: Cui, Wei|Hu, Shirley X|Tang, Zhen-Ya|Hu, Ke-Qin
PMID: 18766003
25.
Journal: Biochimie. 2009 Mar;91(3):373-82.
Title: Bortezomib arrests the proliferation of hepatocellular carcinoma cells HepG2 and JHH6 by differentially affecting E2F1, p21 and p27 levels.
Author: Baiz, Daniele|Pozzato, Gabriele|Dapas, Barbara|Farra, Rossella|Scaggiante, Bruna|Grassi, Mario|Uxa, Laura|Giansante, Carlo|Zennaro, Cristina|Guarnieri, Gianfranco|Grassi, Gabriele
PMID: 19041685
26.
Journal: World J Gastroenterol. 2009 Apr 28;15(16):1943-50.
Title: Effects and mechanisms of silibinin on human hepatocellular carcinoma xenografts in nude mice.
Author: Cui, Wei|Gu, Fan|Hu, Ke-Qin
PMID: 19399925
27.
Journal: Cancer Sci. 2009 Jul;100(7):1234-42.
Title: Role of the miR-106b-25 microRNA cluster in hepatocellular carcinoma.
Author: Li, Yang|Tan, Weiqi|Neo, Thomas W L|Aung, Myat O|Wasser, Shanthi|Lim, Seng G|Tan, Theresa M C
PMID: 19486339
28.
Journal: Cancer Res. 2009 Sep 1;69(17):6951-9.
Title: Blockade of Wnt signaling inhibits angiogenesis and tumor growth in hepatocellular carcinoma.
Author: Hu, Jie|Dong, Aiwen|Fernandez-Ruiz, Veronica|Shan, Juanjuan|Kawa, Milosz|Martinez-Anso, Eduardo|Prieto, Jesus|Qian, Cheng
PMID: 19690140
29.
Journal: Cancer Lett. 2010 Feb 28;288(2):226-35.
Title: Hepatitis B virus X protein overcomes stress-induced premature senescence by repressing p16(INK4a) expression via DNA methylation.
Author: Kim, Ye-Jin|Jung, Jin Kyu|Lee, Sun Young|Jang, Kyung Lib
PMID: 19656618
30.
Journal: J Gen Virol. 2010 Feb;91(Pt 2):493-500.
Title: Hepatitis B virus X protein overcomes the growth-inhibitory potential of retinoic acid by downregulating retinoic acid receptor-beta2 expression via DNA methylation.
Author: Jung, Jin Kyu|Park, Sun-Hye|Jang, Kyung Lib
PMID: 19828754
31.
Journal: J Biol Chem. 2010 Jan 8;285(2):1089-96.
Title: Unique impact of RB loss on hepatic proliferation: tumorigenic stresses uncover distinct pathways of cell cycle control.
Author: Reed, Christopher A|Mayhew, Christopher N|McClendon, A Kathleen|Knudsen, Erik S
PMID: 19887370
32.
Journal: Arch Toxicol. 2010 Feb;84(2):155-64.
Title: Elevation of cell proliferation via generation of reactive oxygen species by piperonyl butoxide contributes to its liver tumor-promoting effects in mice.
Author: Kawai, Masaomi|Saegusa, Yukie|Dewa, Yasuaki|Nishimura, Jihei|Kemmochi, Sayaka|Harada, Tomoaki|Ishii, Yuji|Umemura, Takashi|Shibutani, Makoto|Mitsumori, Kunitoshi
PMID: 20101389
33.
Journal: Biochimie. 2010 May;92(5):455-63.
Title: Serum response factor depletion affects the proliferation of the hepatocellular carcinoma cells HepG2 and JHH6.
Author: Farra, Rossella|Dapas, Barbara|Pozzato, Gabriele|Giansante, Carlo|Heidenreich, Olaf|Uxa, Laura|Zennaro, Cristina|Guarnieri, Gianfranco|Grassi, Gabriele
PMID: 20144681
34.
Journal: Hepatology. 2010 May;51(5):1614-23.
Title: miR-17-5p Promotes migration of human hepatocellular carcinoma cells through the p38 mitogen-activated protein kinase-heat shock protein 27 pathway.
Author: Yang, Fu|Yin, Yixuan|Wang, Fang|Wang, Yuqi|Zhang, Ling|Tang, Ying|Sun, Shuhan
PMID: 20209605
35.
Journal: Toxicol Sci. 2010 Oct;117(2):381-92.
Title: Time series analysis of benzo[A]pyrene-induced transcriptome changes suggests that a network of transcription factors regulates the effects on functional gene sets.
Author: van Delft, Joost H M|Mathijs, Karen|Staal, Yvonne C M|van Herwijnen, Marcel H M|Brauers, Karen J J|Boorsma, Andre|Kleinjans, Jos C S
PMID: 20624995
36.
Journal: Sci Transl Med. 2010 Oct 20;2(54):54ra77.
Title: An integrated genomic and epigenomic approach predicts therapeutic response to zebularine in human liver cancer.
Author: Andersen, Jesper B|Factor, Valentina M|Marquardt, Jens U|Raggi, Chiara|Lee, Yun-Han|Seo, Daekwan|Conner, Elizabeth A|Thorgeirsson, Snorri S
PMID: 20962331
37.
Journal: J Hepatol. 2011 Jul;55(1):111-9.
Title: Mybl2 expression is under genetic control and contributes to determine a hepatocellular carcinoma susceptible phenotype.
Author: Frau, Maddalena|Ladu, Sara|Calvisi, Diego F|Simile, Maria M|Bonelli, Piero|Daino, Lucia|Tomasi, Maria L|Seddaiu, Maria A|Feo, Francesco|Pascale, Rosa M
PMID: 21419759
38.
Journal: Chin J Cancer. 2011 Apr;30(4):273-9.
Title: Hepatitis B virus X protein regulates the mEZH2 promoter via the E2F1-binding site in AML12 cells.
Author: Shi, Xiao-Yan|Zhang, Ying-Ying|Zhou, Xiao-Wei|Lu, Jian-Sheng|Guo, Ze-Kun|Huang, Pei-Tang
PMID: 21439249
39.
Journal: Hepatology. 2011 Apr;53(4):1226-36.
Title: Activation of v-Myb avian myeloblastosis viral oncogene homolog-like2 (MYBL2)-LIN9 complex contributes to human hepatocarcinogenesis and identifies a subset of hepatocellular carcinoma with mutant p53.
Author: Calvisi, Diego F|Simile, Maria M|Ladu, Sara|Frau, Maddalena|Evert, Matthias|Tomasi, Maria L|Demartis, Maria I|Daino, Lucia|Seddaiu, Maria A|Brozzetti, Stefania|Feo, Francesco|Pascale, Rosa M
PMID: 21480327
40.
Journal: Eur J Cell Biol. 2011 Aug;90(8):657-64.
Title: Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPARalpha-independent mechanisms.
Author: Yamasaki, Daisuke|Kawabe, Natsuko|Nakamura, Hitomi|Tachibana, Keisuke|Ishimoto, Kenji|Tanaka, Toshiya|Aburatani, Hiroyuki|Sakai, Juro|Hamakubo, Takao|Kodama, Tatsuhiko|Doi, Takefumi
PMID: 21514001
41.
Journal: Cancer Lett. 2011 Nov 1;310(1):61-8.
Title: Hepatitis C virus Core protein stimulates cell growth by down-regulating p16 expression via DNA methylation.
Author: Park, Sun-Hye|Lim, Joo Song|Lim, Su-Yeon|Tiwari, Indira|Jang, Kyung Lib
PMID: 21757290
42.
Journal: Dig Liver Dis. 2011 Dec;43(12):1006-14.
Title: Effects of E2F1-cyclin E1-E2 circuit down regulation in hepatocellular carcinoma cells.
Author: Farra, Rossella|Dapas, Barbara|Pozzato, Gabriele|Scaggiante, Bruna|Agostini, Francesco|Zennaro, Cristina|Grassi, Mario|Rosso, Natalia|Giansante, Carlo|Fiotti, Nicola|Grassi, Gabriele
PMID: 21831731
43.
Journal: Hepatology. 2012 Jul;56(1):165-75.
Title: Role of transcriptional and posttranscriptional regulation of methionine adenosyltransferases in liver cancer progression.
Author: Frau, Maddalena|Tomasi, Maria L|Simile, Maria M|Demartis, Maria I|Salis, Fabiana|Latte, Gavinella|Calvisi, Diego F|Seddaiu, Maria A|Daino, Lucia|Feo, Claudio F|Brozzetti, Stefania|Solinas, Giuliana|Yamashita, Satoshi|Ushijima, Toshikazu|Feo, Francesco|Pas
PMID: 22318685
44.
Journal: J Biol Chem. 2012 Jun 8;287(24):20545-54.
Title: HBx protein of hepatitis B virus promotes reinitiation of DNA replication by regulating expression and intracellular stability of replication licensing factor CDC6.
Author: Pandey, Vijaya|Kumar, Vijay
PMID: 22523071
45.
Journal: Oncol Rep. 2012 Aug;28(2):742-8.
Title: Water extract of Hedyotis Diffusa Willd suppresses proliferation of human HepG2 cells and potentiates the anticancer efficacy of low-dose 5-fluorouracil by inhibiting the CDK2-E2F1 pathway.
Author: Chen, Xu-Zheng|Cao, Zhi-Yun|Chen, Tuan-Sheng|Zhang, You-Quan|Liu, Zhi-Zhen|Su, Yin-Tao|Liao, Lian-Ming|Du, Jian
PMID: 22641337
46.
Journal: Ann Surg Oncol. 2013 Nov;20(12):4041-54.
Title: The E2F transcription factor 1 transactives stathmin 1 in hepatocellular carcinoma.
Author: Chen, Yi-Ling|Uen, Yih-Huei|Li, Chien-Feng|Horng, Kuo-Chan|Chen, Lih-Ren|Wu, Wen-Ren|Tseng, Hong-Yu|Huang, Hsuan-Ying|Wu, Li-Ching|Shiue, Yow-Ling
PMID: 22911364
47.
Journal: Fitoterapia. 2013 Jan;84:123-9.
Title: Sasanquasaponin from Camellia oleifera Abel. induces cell cycle arrest and apoptosis in human breast cancer MCF-7 cells.
Author: Chen, Linyan|Chen, Jing|Xu, Hanhong
PMID: 23164604
48.
Journal: Hepatology. 2013 Mar;57(3):1088-97.
Title: Hypoxia inducible factor 2 alpha inhibits hepatocellular carcinoma growth through the transcription factor dimerization partner 3/ E2F transcription factor 1-dependent apoptotic pathway.
Author: Sun, Hai-Xiang|Xu, Yang|Yang, Xin-Rong|Wang, Wei-Min|Bai, Haibo|Shi, Ruo-Yu|Nayar, Suresh K|Devbhandari, Ranjan P|He, Yi-zhou|Zhu, Qin-Feng|Sun, Yun-Fan|Hu, Bo|Khan, Mehtab|Anders, Robert A|Fan, Jia
PMID: 23212661
49.
Journal: J Hepatol. 2013 Jun;58(6):1068-73.
Title: HBV core promoter mutations promote cellular proliferation through E2F1-mediated upregulation of S-phase kinase-associated protein 2 transcription.
Author: Huang, Yuehua|Tai, Andrew W|Tong, Shuping|Lok, Anna S F
PMID: 23348237
50.
Journal: PLoS One. 2013 Apr 22;8(4):e61768.
Title: RNA-Seq profiling reveals novel hepatic gene expression pattern in aflatoxin B1 treated rats.
Author: Merrick, B Alex|Phadke, Dhiral P|Auerbach, Scott S|Mav, Deepak|Stiegelmeyer, Suzy M|Shah, Ruchir R|Tice, Raymond R
PMID: 23630614
51.
Journal: Toxicol Appl Pharmacol. 2013 Sep 1;271(2):137-43.
Title: Dichlorodiphenyltrichloroethane technical mixture regulates cell cycle and apoptosis genes through the activation of CAR and ERalpha in mouse livers.
Author: Kazantseva, Yuliya A|Yarushkin, Andrei A|Pustylnyak, Vladimir O
PMID: 23684557
52.
Journal: World J Gastroenterol. 2013 Jun 7;19(21):3189-98.
Title: E2F transcription factors and digestive system malignancies: how much do we know?
Author: Xanthoulis, Athanasios|Tiniakos, Dina G
PMID: 23745020
53.
Journal: J Cell Sci. 2013 Oct 15;126(Pt 20):4636-46.
Title: Promoter occupancy of MLL1 histone methyltransferase seems to specify the proliferative and apoptotic functions of E2F1 in a tumour microenvironment.
Author: Swarnalatha, Manickavinayaham|Singh, Anup Kumar|Kumar, Vijay
PMID: 23868976
54.
Journal: Am J Pathol. 2013 Dec;183(6):1719-1730.
Title: Hepatic loss of miR-122 predisposes mice to hepatobiliary cyst and hepatocellular carcinoma upon diethylnitrosamine exposure.
Author: Hsu, Shu-Hao|Wang, Bo|Kutay, Huban|Bid, Hemant|Shreve, Julia|Zhang, Xiaoli|Costinean, Stefan|Bratasz, Anna|Houghton, Peter|Ghoshal, Kalpana
PMID: 24113455
55.
Journal: PLoS One. 2013 Nov 4;8(11):e78624.
Title: iSubgraph: integrative genomics for subgroup discovery in hepatocellular carcinoma using graph mining and mixture models.
Author: Ozdemir, Bahadir|Abd-Almageed, Wael|Roessler, Stephanie|Wang, Xin Wei
PMID: 24223834
56.
Journal: Hepatology. 2014 Feb;59(2):555-66.
Title: Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2.
Author: Wang, Bo|Hsu, Shu-hao|Wang, Xinmei|Kutay, Huban|Bid, Hemant Kumar|Yu, Jianhua|Ganju, Ramesh K|Jacob, Samson T|Yuneva, Mariia|Ghoshal, Kalpana
PMID: 24038073
57.
Journal: Oncol Rep. 2014 Feb;31(2):933-9.
Title: Notch1 is a potential therapeutic target for the treatment of human hepatitis B virus X protein-associated hepatocellular carcinoma.
Author: Sun, Qian|Wang, Ronghua|Wang, Yan|Luo, Jing|Wang, Peng|Cheng, Bin
PMID: 24336972
58.
Journal: Oncol Rep. 2014 Feb;31(2):573-80.
Title: Active form of AKT controls cell proliferation and response to apoptosis in hepatocellular carcinoma.
Author: Kunter, Imge|Erdal, Esra|Nart, Deniz|Yilmaz, Funda|Karademir, Sedat|Sagol, Ozgul|Atabey, Nese
PMID: 24337632
59.
Journal: Gene. 2014 Mar 10;537(2):253-9.
Title: TFDP3 was expressed in coordination with E2F1 to inhibit E2F1-mediated apoptosis in prostate cancer.
Author: Ma, Yueyun|Xin, Yijuan|Li, Rui|Wang, Zhe|Yue, Qiaohong|Xiao, Fengjing|Hao, Xiaoke
PMID: 24406621
60.
Journal: Cell Signal. 2014 May;26(5):1075-81.
Title: Promising roles of mammalian E2Fs in hepatocellular carcinoma.
Author: Zhan, Lei|Huang, Cheng|Meng, Xiao Ming|Song, Yang|Wu, Xiao Qin|Miu, Cheng Gui|Zhan, Xiang Shu|Li, Jun
PMID: 24440307
61.
Journal: World J Gastroenterol. 2014 Jan 21;20(3):795-803.
Title: Bortezomib effect on E2F and cyclin family members in human hepatocellular carcinoma cell lines.
Author: Baiz, Daniele|Dapas, Barbara|Farra, Rossella|Scaggiante, Bruna|Pozzato, Gabriele|Zanconati, Fabrizio|Fiotti, Nicola|Consoloni, Lara|Chiaretti, Sara|Grassi, Gabriele
PMID: 24574752
62.
Journal: Asian Pac J Cancer Prev. 2014;15(6):2565-70.
Title: Aflatoxin B1 promotes cell growth and invasion in hepatocellular carcinoma HepG2 cells through H19 and E2F1.
Author: Lv, Jun|Yu, Ya-Qun|Li, Shu-Qun|Luo, Liang|Wang, Qian
PMID: 24761865
63.
Journal: Hepatology. 2014 Oct;60(4):1241-50.
Title: Overexpression of far upstream element (FUSE) binding protein (FBP)-interacting repressor (FIR) supports growth of hepatocellular carcinoma.
Author: Malz, Mona|Bovet, Michael|Samarin, Jana|Rabenhorst, Uta|Sticht, Carsten|Bissinger, Michaela|Roessler, Stephanie|Bermejo, Justo Lorenzo|Renner, Marcus|Calvisi, Diego Francesco|Singer, Stephan|Ganzinger, Matthias|Weber, Achim|Gretz, Norbert|Zornig, Martin|S
PMID: 24824848
64.
Journal: J Hepatol. 2014 Oct;61(4):832-9.
Title: The functional and mechanistic relatedness of EZH2 and menin in hepatocellular carcinoma.
Author: Gao, Shu-Bin|Xu, Bin|Ding, Li-Hong|Zheng, Qi-Lin|Zhang, Li|Zheng, Qi-Fan|Li, Shan-Hua|Feng, Zi-Jie|Wei, Jie|Yin, Zhen-Yu|Hua, Xianxin|Jin, Guang-Hui
PMID: 24845612
65.
Journal: World J Gastroenterol. 2014 May 28;20(20):5962-72.
Title: miR-106b-25/miR-17-92 clusters: polycistrons with oncogenic roles in hepatocellular carcinoma.
Author: Tan, Weiqi|Li, Yang|Lim, Seng-Gee|Tan, Theresa M C
PMID: 24876719
66.
Journal: Cancer Lett. 2014 Oct 1;352(2):169-78.
Title: The oncoprotein HBXIP up-regulates SCG3 through modulating E2F1 and miR-509-3p in hepatoma cells.
Author: Wang, Yue|Cui, Ming|Cai, Xiaoli|Sun, Baodi|Liu, Fabao|Zhang, Xiaodong|Ye, Lihong
PMID: 24882622
67.
Journal: Mol Cancer Res. 2014 Oct;12(10):1388-97.
Title: EZH2 represses target genes through H3K27-dependent and H3K27-independent mechanisms in hepatocellular carcinoma.
Author: Gao, Shu-Bin|Zheng, Qi-Fan|Xu, Bin|Pan, Chang-Bao|Li, Kang-Li|Zhao, Yue|Zheng, Qi-Lin|Lin, Xiao|Xue, Li-Xiang|Jin, Guang-Hui
PMID: 24916103
68.
Journal: Oncotarget. 2014 Nov 15;5(21):10318-31.
Title: Specific genomic and transcriptomic aberrations in tumors induced by partial hepatectomy of a chronically inflamed murine liver.
Author: Ella, Ezra|Heim, Denise|Stoyanov, Evgeniy|Harari-Steinfeld, Rona|Steinfeld, Israel|Pappo, Orit|Perlman, Temima Schnitzer|Nachmansson, Natalie|Rivkin, Ludmila|Olam, Devorah|Abramovitch, Rinat|Wege, Henning|Galun, Eithan|Goldenberg, Daniel
PMID: 25401338
69.
Journal: Gut. 2015 Jan;64(1):156-67.
Title: Epigenetic modification of MiR-429 promotes liver tumour-initiating cell properties by targeting Rb binding protein 4.
Author: Li, Liang|Tang, Jing|Zhang, Baohua|Yang, Wen|LiuGao, Miyang|Wang, Ruoyu|Tan, Yexiong|Fan, Jianling|Chang, Yanxin|Fu, Jing|Jiang, Feng|Chen, Caiyang|Yang, Yingcheng|Gu, Jin|Wu, Dingming|Guo, Linna|Cao, Dan|Li, Hengyu|Cao, Guangwen|Wu, Mengchao|Zhang, Micha
PMID: 24572141
70.
Journal: J Hepatol. 2015 May;62(5):1100-11.
Title: A CCRK-EZH2 epigenetic circuitry drives hepatocarcinogenesis and associates with tumor recurrence and poor survival of patients.
Author: Feng, Hai|Yu, Zhuo|Tian, Yuan|Lee, Ying-Ying|Li, May S|Go, Minnie Y Y|Cheung, Yue-Sun|Lai, Paul B S|Chan, Andrew M L|To, Ka-Fai|Chan, Henry L Y|Sung, Joseph J Y|Cheng, Alfred S L
PMID: 25500144
71.
Journal: Biochimie. 2015 May;112:85-95.
Title: Impairment of the Pin1/E2F1 axis in the anti-proliferative effect of bortezomib in hepatocellular carcinoma cells.
Author: Farra, Rossella|Dapas, Barbara|Baiz, Daniele|Tonon, Federica|Chiaretti, Sara|Del Sal, Giannino|Rustighi, Alessandra|Elvassore, Nicola|Pozzato, Gabriele|Grassi, Mario|Grassi, Gabriele
PMID: 25742740
72.
Journal: Lab Invest. 2015 Jun;95(6):648-659.
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Title: MiR-429 increases the metastatic capability of HCC via regulating classic Wnt pathway rather than epithelial-mesenchymal transition.
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Title: Hepatitis B virus induces RNR-R2 expression via DNA damage response activation.
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Journal: Toxicol Appl Pharmacol. 2015 Oct 1;288(1):26-32.
Title: Xenosensor CAR mediates down-regulation of miR-122 and up-regulation of miR-122 targets in the liver.
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Journal: Mol Cancer Ther. 2015 Nov;14(11):2623-33.
Title: HMDB and 5-AzadC Combination Reverses Tumor Suppressor CCAAT/Enhancer-Binding Protein Delta to Strengthen the Death of Liver Cancer Cells.
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Journal: Mol Med Rep. 2015 Dec;12(6):7963-70.
Title: Cannabinoid WIN55, 212-2 induces cell cycle arrest and inhibits the proliferation and migration of human BEL7402 hepatocellular carcinoma cells.
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Journal: Nat Commun. 2015 Oct 29;6:8704.
Title: POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation.
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Title: Recruitment of Pontin/Reptin by E2f1 amplifies E2f transcriptional response during cancer progression.
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Journal: J Cell Biochem. 2016 Jun;117(6):1308-18.
Title: Elevated Expression of Hepatoma Up-Regulated Protein Inhibits gamma-Irradiation-Induced Apoptosis of Prostate Cancer Cells.
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Journal: Oncotarget. 2016 Jan 5;7(1):241-54.
Title: Long non-coding RNA HULC promotes tumor angiogenesis in liver cancer by up-regulating sphingosine kinase 1 (SPHK1).
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Journal: Tumour Biol. 2016 May;37(5):5951-61.
Title: Derivate isocorydine inhibits cell proliferation in hepatocellular carcinoma cell lines by inducing G2/M cell cycle arrest and apoptosis.
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Journal: Int J Biol Sci. 2016 Jan 1;12(1):30-41.
Title: Hepatitis B Virus X Protein Upregulates hELG1/ ATAD5 Expression through E2F1 in Hepatocellular Carcinoma.
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Journal: Cell Metab. 2016 Jan 12;23(1):206-19.
Title: NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism.
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Journal: Oncotarget. 2016 Jun 14;7(24):36924-36939.
Title: Intestine-specific homeobox (ISX) upregulates E2F1 expression and related oncogenic activities in HCC.
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Journal: Oncotarget. 2016 Jul 19;7(29):45863-45875.
Title: Chromatin remodeling gene ARID2 targets cyclin D1 and cyclin E1 to suppress hepatoma cell progression.
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Title: Histone acetyl transferase GCN5 promotes human hepatocellular carcinoma progression by enhancing AIB1 expression.
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Journal: PLoS One. 2016 Aug 15;11(8):e0161025.
Title: A Hybrid Chalcone Combining the Trimethoxyphenyl and Isatinyl Groups Targets Multiple Oncogenic Proteins and Pathways in Hepatocellular Carcinoma Cells.
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Journal: Int J Mol Sci. 2016 Sep 8;17(9). pii: ijms17091501.
Title: Downregulation of FOXP1 Inhibits Cell Proliferation in Hepatocellular Carcinoma by Inducing G1/S Phase Cell Cycle Arrest.
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Journal: Epigenetics. 2016 Aug 11:1-12.
Title: Efficacy and epigenetic interactions of novel DNA hypomethylating agent guadecitabine (SGI-110) in preclinical models of hepatocellular carcinoma.
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Journal: Sci Rep. 2016 Oct 25;6:35917.
Title: HBV core promoter mutations and AKT upregulate S-phase kinase-associated protein 2 to promote postoperative hepatocellular carcinoma progression.
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Journal: Curr Drug Deliv. 2017;14(2):272-281.
Title: The Role of the Transcription Factor E2F1 in Hepatocellular Carcinoma.
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Journal: Hepatology. 2017 Apr;65(4):1352-1368.
Title: Growth factor receptor binding protein 14 inhibition triggers insulin-induced mouse hepatocyte proliferation and is associated with hepatocellular carcinoma.
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Journal: Mol Pharmacol. 2017 Mar;91(3):189-196.
Title: Pyruvate Dehydrogenase Kinase 4 Deficiency Results in Expedited Cellular Proliferation through E2F1-Mediated Increase of Cyclins.
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Title: Galactosylated polyaspartamide copolymers for siRNA targeted delivery to hepatocellular carcinoma cells.
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Journal: J Clin Invest. 2017 Mar 1;127(3):830-842.
Title: Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.
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Title: Dissecting the role of the elongation factor 1A isoforms in hepatocellular carcinoma cells by liposome-mediated delivery of siRNAs.
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Title: Derivate Isocorydine (d-ICD) Suppresses Migration and Invasion of Hepatocellular Carcinoma Cell by Downregulating ITGA1 Expression.
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Title: From big data to diagnosis and prognosis: gene expression signatures in liver hepatocellular carcinoma.
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Journal: Mol Carcinog. 2017 Oct;56(10):2167-2177.
Title: Aryl hydrocarbon receptor promotes hepatocellular carcinoma tumorigenesis by targeting intestine-specific homeobox expression.
Author: Hsu, Shih-Hsien|Wang, Li-Ting|Chai, Chee-Yin|Wu, Chi-Cheng|Hsi, Edward|Chiou, Shyh-Shin|Wang, Shen-Nien
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Journal: Oncotarget. 2017 Apr 4;8(14):23775-23786.
Title: A novel lncRNA, GASL1, inhibits cell proliferation and restricts E2F1 activity.
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Journal: Cancer Cell Int. 2017 May 30;17:59.
Title: Berberine regulates the protein expression of multiple tumorigenesis-related genes in hepatocellular carcinoma cell lines.
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Journal: J Cancer. 2017 Apr 9;8(7):1205-1213.
Title: E2F8 is a Potential Therapeutic Target for Hepatocellular Carcinoma.
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Title: Up-regulation of CDK16 by multiple mechanisms in hepatocellular carcinoma promotes tumor progression.
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Journal: Oncol Rep. 2017 Nov;38(5):2951-2958.
Title: Celastrol downregulates E2F1 to induce growth inhibitory effects in hepatocellular carcinoma HepG2 cells.
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Journal: Oncotarget. 2017 Aug 1;8(51):88517-88528.
Title: MicroRNA deregulation in nonalcoholic steatohepatitis-associated liver carcinogenesis.
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Journal: Hepatol Commun. 2017 Oct;1(8):816-830.
Title: High-mobility-group protein 2 regulated by microRNA-127 and small heterodimer partner modulates pluripotency of mouse embryonic stem cells and liver tumor initiating cells.
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Journal: J Cell Physiol. 2018 Feb;233(2):1312-1320.
Title: E2F is involved in radioresistance of carbon ion induced apoptosis via Bax/caspase 3 signal pathway in human hepatoma cell.
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Journal: Iran Biomed J. 2018 May 1;22(3):171-9. Epub 2017 Oct 10.
Title: Nanocurcumin-Mediated Down-Regulation of Telomerase Via Stimulating TGFbeta1 Signaling Pathway in Hepatocellular Carcinoma Cells
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Journal: Cancer Prev Res (Phila). 2018 Feb;11(2):103-112.
Title: Prevalence of Aflatoxin-Associated TP53R249S Mutation in Hepatocellular Carcinoma in Hispanics in South Texas.
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Journal: Mol Med Rep. 2018 Jan;17(1):342-349.
Title: SIRT5 promotes cell proliferation and invasion in hepatocellular carcinoma by targeting E2F1.
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Journal: Anticancer Res. 2018 Feb;38(2):737-743.
Title: Effective Timing of Surgical Resection of Colorectal Cancer Liver Metastases During Chemotherapy.
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Journal: J Gastroenterol Hepatol. 2018 Apr 19.
Title: Insights into the etiology-associated gene regulatory networks in hepatocellular carcinoma from The Cancer Genome Atlas.
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Journal: Mol Cancer Res. 2018 Aug 6. pii: 1541-7786.MCR-18-0313.
Title: Integrated Genomic Comparison of Mouse Models Reveals Their Clinical Resemblance to Human Liver Cancer.
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Journal: Oncol Rep. 2018 Oct;40(4):1863-1874.
Title: SET7/9 promotes hepatocellular carcinoma progression through regulation of E2F1.
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Journal: Carcinogenesis. 2018 Sep 25. pii: 5106955.
Title: MicroRNA-34a Promotes MICB Expression in Hepatocytes.
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Journal: Oncotarget. 2018 Sep 28;9(76):34320-34335.
Title: Overexpression of KDM5B/JARID1B is associated with poor prognosis in hepatocellular carcinoma.
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