Primary Site >> Colorectal Cancer

Gene >> DOT1L

Journal: PLoS Biol. 2010 Nov 16;8(11):e1000539.
Title: The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/beta-catenin coactivators essential for intestinal homeostasis.
Author: Mahmoudi, Tokameh|Boj, Sylvia F|Hatzis, Pantelis|Li, Vivian S W|Taouatas, Nadia|Vries, Robert G J|Teunissen, Hans|Begthel, Harry|Korving, Jeroen|Mohammed, Shabaz|Heck, Albert J R|Clevers, Hans
PMID: 21103407
Journal: Immunity. 2014 May 15;40(5):772-84.
Title: IL-22(+)CD4(+) T cells promote colorectal cancer stemness via STAT3 transcription factor activation and induction of the methyltransferase DOT1L.
Author: Kryczek, Ilona|Lin, Yanwei|Nagarsheth, Nisha|Peng, Dongjun|Zhao, Lili|Zhao, Ende|Vatan, Linda|Szeliga, Wojciech|Dou, Yali|Owens, Scott|Zgodzinski, Witold|Majewski, Marek|Wallner, Grzegorz|Fang, Jingyuan|Huang, Emina|Zou, Weiping
PMID: 24816405
Journal: ACS Chem Biol. 2015 Jan 16;10(1):109-14.
Title: Regulation of Wnt signaling target gene expression by the histone methyltransferase DOT1L.
Author: Gibbons, Garrett S|Owens, Scott R|Fearon, Eric R|Nikolovska-Coleska, Zaneta
PMID: 25361163
Journal: Therap Adv Gastroenterol. 2017 Jan;10(1):114-131.
Title: Targeting histone methylation for colorectal cancer.
Author: Huang, Tao|Lin, Chengyuan|Zhong, Linda L D|Zhao, Ling|Zhang, Ge|Lu, Aiping|Wu, Jiang|Bian, Zhaoxiang
PMID: 28286564