Primary Site >> Pancreatic Cancer

Gene >> DNMT3A

Journal: FASEB J. 2008 Aug;22(8):3035-45.
Title: Epigenetic regulation of the human mucin gene MUC4 in epithelial cancer cell lines involves both DNA methylation and histone modifications mediated by DNA methyltransferases and histone deacetylases.
Author: Vincent, Audrey|Ducourouble, Marie-Paule|Van Seuningen, Isabelle
PMID: 18492726
Journal: Mol Cells. 2011 Jun;31(6):579-83.
Title: Silencing of BNIP3 results from promoter methylation by DNA methyltransferase 1 induced by the mitogen-activated protein kinase pathway.
Author: An, Hyun-Jung|Lee, Hayyoung|Paik, Sang-Gi
PMID: 21573703
Journal: PLoS One. 2011;6(11):e27684.
Title: Expression of DNMT1 and DNMT3a are regulated by GLI1 in human pancreatic cancer.
Author: He, ShanShan|Wang, Feng|Yang, LiJuan|Guo, ChuanYong|Wan, Rong|Ke, AiWu|Xu, Ling|Hu, GuoYong|Xu, XuanFu|Shen, Jie|Wang, XingPeng
PMID: 22110720
Journal: Clin Transl Oncol. 2012 Feb;14(2):116-24.
Title: Association of increased DNA methyltransferase expression with carcinogenesis and poor prognosis in pancreatic ductal adenocarcinoma.
Author: Zhang, Jing-Jing|Zhu, Yi|Zhu, Yan|Wu, Jun-Li|Liang, Wen-Biao|Zhu, Rong|Xu, Ze-Kuan|Du, Qing|Miao, Yi
PMID: 22301400
Journal: J Carcinog Mutagen. 2014 May 31;5:177.
Title: Induction of Apoptosis in Pancreatic Cancer Cells by CDDO-Me Involves Repression of Telomerase through Epigenetic Pathways.
Author: Deeb, Dorrah|Brigolin, Chris|Gao, Xiaohua|Liu, Yongbo|Pindolia, Kirit R|Gautam, Subhash C
PMID: 25152840
Journal: World J Stem Cells. 2015 Jan 26;7(1):137-48.
Title: Epigenetic therapy of cancer stem and progenitor cells by targeting DNA methylation machineries.
Author: Wongtrakoongate, Patompon
PMID: 25621113
Journal: Oncol Rep. 2016 Apr;35(4):1941-9.
Title: Emodin enhances the demethylation by 5-Aza-CdR of pancreatic cancer cell tumor-suppressor genes P16, RASSF1A and ppENK.
Author: Pan, Feng-Ping|Zhou, Hong-Kun|Bu, He-Qi|Chen, Zi-Qiang|Zhang, Hao|Xu, Lu-Ping|Tang, Jian|Yu, Qing-Jiang|Chu, Yong-Quan|Pan, Jie|Fei, Yong|Lin, Sheng-Zhang|Liu, Dian-Lei|Chen, Liang
PMID: 26782786
Journal: Cancer Lett. 2017 Aug 28;402:110-116.
Title: Epigenetic effects of inhibition of heat shock protein 90 (HSP90) in human pancreatic and colon cancer.
Author: Nagaraju, Ganji Purnachandra|Wu, Christina|Merchant, Neha|Chen, Zhengjia|Lesinski, Gregory B|El-Rayes, Bassel F
PMID: 28583846
Journal: Mol Med Rep. 2018 Jan;17(1):117-124.
Title: DNA methyltransferase 3a modulates chemosensitivity to gemcitabine and oxaliplatin via CHK1 and AKT in p53deficient pancreatic cancer cells.
Author: Jing, Wei|Song, Na|Liu, Yunpeng|Qu, Xiujuan|Hou, Kezuo|Yang, Xianghong|Che, Xiaofang
PMID: 29115606
Journal: Mol Med Rep. 2018 Feb;17(2):2113-2120.
Title: Downregulation of miR29b targets DNMT3b to suppress cellular apoptosis and enhance proliferation in pancreatic cancer.
Author: Wang, Li-Hua|Huang, Ju|Wu, Cheng-Rong|Huang, Liu-Ye|Cui, Jun|Xing, Zhi-Zhi|Zhao, Chun-Yu
PMID: 29207141
Journal: Biochem Biophys Res Commun. 2018 May 23;499(4):934-940.
Title: Nicotine induces aberrant hypermethylation of tumor suppressor genes in pancreatic epithelial ductal cells.
Author: Jin, Tong|Hao, Jianyu|Fan, Daiming
PMID: 29626481