Literatures

Primary Site >> Colorectal Cancer

Gene >> DNMT3A

1.
Journal:	Cancer Res. 1999 May 15;59(10):2302-6.
Title:	CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression.
Author:	Eads, C A\|Danenberg, K D\|Kawakami, K\|Saltz, L B\|Danenberg, P V\|Laird, P W
PMID:	10344733

2.
Journal:	Nat Genet. 2003 Jan;33(1):61-5. Epub 2002 Dec 23.
Title:	DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells.
Author:	Robert, Marie-France\|Morin, Steves\|Beaulieu, Normand\|Gauthier, France\|Chute, Ian C\|Barsalou, Annie\|MacLeod, A Robert
PMID:	12496760

3.
Journal:	Cancer Biol Ther. 2003 May-Jun;2(3):259-63.
Title:	Mitoxantrone mediates demethylation and reexpression of cyclin d2, estrogen receptor and 14.3.3sigma in breast cancer cells.
Author:	Parker, Belinda S\|Cutts, Suzanne M\|Nudelman, Abraham\|Rephaeli, Ada\|Phillips, Don R\|Sukumar, Saraswati
PMID:	12878861

4.
Journal:	J Pharmacol Exp Ther. 2005 Feb;312(2):525-36. Epub 2004 Nov 16.
Title:	5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms.
Author:	Schneider-Stock, Regine\|Diab-Assef, Mona\|Rohrbeck, Astrid\|Foltzer-Jourdainne, Charlotte\|Boltze, Carsten\|Hartig, Roland\|Schonfeld, Peter\|Roessner, Albert\|Gali-Muhtasib, Hala
PMID:	15547111

5.
Journal:	J Biol Chem. 2005 Dec 9;280(49):40749-56. Epub 2005 Oct 17.
Title:	Procainamide is a specific inhibitor of DNA methyltransferase 1.
Author:	Lee, Byron H\|Yegnasubramanian, Srinivasan\|Lin, Xiaohui\|Nelson, William G
PMID:	16230360

6.
Journal:	Cancer Res. 2006 Jan 15;66(2):682-92.
Title:	De novo CpG island methylation in human cancer cells.
Author:	Jair, Kam-Wing\|Bachman, Kurtis E\|Suzuki, Hiromu\|Ting, Angela H\|Rhee, Ina\|Yen, Ray-Whay Chiu\|Baylin, Stephen B\|Schuebel, Kornel E
PMID:	16423997

7.
Journal:	J Biol Chem. 2006 Aug 4;281(31):22062-72. Epub 2006 May 30.
Title:	Role of DNA methyltransferases in regulation of human ribosomal RNA gene transcription.
Author:	Majumder, Sarmila\|Ghoshal, Kalpana\|Datta, Jharna\|Smith, David Spencer\|Bai, Shoumei\|Jacob, Samson T
PMID:	16735507

8.
Journal:	Zhonghua Zhong Liu Za Zhi. 2006 Aug;28(8):564-7.
Title:	[The effect of PKC-delta inhibitor Rottlerin on human colon cancer cell line SW1116 and its mechanism].
Author:	Chen, Zhao-fei\|Fang, Jing-yuan\|Weng, Yu-rong\|Sun, Dan-feng\|Wang, Xia\|Lu, Rong
PMID:	17236547

9.
Journal:	Mol Carcinog. 2007 Sep;46(9):766-72.
Title:	Progressive up-regulation of genes encoding DNA methyltransferases in the colorectal adenoma-carcinoma sequence.
Author:	Schmidt, Wolfgang M\|Sedivy, Roland\|Forstner, Birgit\|Steger, Gunther G\|Zochbauer-Muller, Sabine\|Mader, Robert M
PMID:	17538945

10.
Journal:	Cancer Res. 2009 Sep 15;69(18):7412-21.
Title:	DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer.
Author:	Jin, Bilian\|Yao, Bing\|Li, Jian-Liang\|Fields, C Robert\|Delmas, Amber L\|Liu, Chen\|Robertson, Keith D
PMID:	19723660

11.
Journal:	Br J Cancer. 2009 Aug 18;101(4):699-706.
Title:	MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer.
Author:	Ng, E K O\|Tsang, W P\|Ng, S S M\|Jin, H C\|Yu, J\|Li, J J\|Rocken, C\|Ebert, M P A\|Kwok, T T\|Sung, J J Y
PMID:	19638978

12.
Journal:	Gastroenterology. 2009 Sep;137(3):902-13, 913.e1-11.
Title:	Elevated Dnmt3a activity promotes polyposis in Apc(Min) mice by relaxing extracellular restraints on Wnt signaling.
Author:	Samuel, Michael S\|Suzuki, Hiromu\|Buchert, Michael\|Putoczki, Tracy L\|Tebbutt, Niall C\|Lundgren-May, Therese\|Christou, Aliki\|Inglese, Melissa\|Toyota, Minoru\|Heath, Joan K\|Ward, Robyn L\|Waring, Paul M\|Ernst, Matthias
PMID:	19454286

13.
Journal:	Biomed Pharmacother. 2009 Aug;63(7):492-500.
Title:	5-Aza-2'-deoxycytidine reactivates expression of RUNX3 by deletion of DNA methyltransferases leading to caspase independent apoptosis in colorectal cancer Lovo cells.
Author:	Deng, Tao\|Zhang, Yan
PMID:	18848767

14.
Journal:	Curr Opin Gastroenterol. 2010 Jan;26(1):47-52.
Title:	Recent insights into the pathogenesis of colorectal cancer.
Author:	Goel, Ajay\|Boland, Clement Richard
PMID:	19786869

15.
Journal:	J Huazhong Univ Sci Technolog Med Sci. 2010 Feb;30(1):69-74.
Title:	Epigenetic regulation of the ERbeta gene on the estrogen signal transfection pathway in colon cancer cells.
Author:	Zhai, Ronglin\|Wang, Guobin\|Cai, Kailin\|Tao, Kaixiong\|Xu, Fei\|Zhang, Wanli\|Wang, Zhiyong
PMID:	20155458

16.
Journal:	Epigenetics. 2010 Aug 16;5(6):547-56. Epub 2010 Aug 16.
Title:	Ischemia dysregulates DNA methyltransferases and p16INK4a methylation in human colorectal cancer cells.
Author:	Skowronski, Karolina\|Dubey, Sonam\|Rodenhiser, David\|Coomber, Brenda
PMID:	20543577

17.
Journal:	Int J Cancer. 2011 Feb 1;128(3):551-61.
Title:	DNMT3a plays a role in switches between doxorubicin-induced senescence and apoptosis of colorectal cancer cells.
Author:	Zhang, Yu\|Gao, Yanyan\|Zhang, Guoping\|Huang, Shuyan\|Dong, Zhixiong\|Kong, Chenfei\|Su, Dongmei\|Du, Juan\|Zhu, Shan\|Liang, Qian\|Zhang, Jianchao\|Lu, Jun\|Huang, Baiqu
PMID:	20473858

18.
Journal:	Oncol Lett. 2012 Feb;3(2):450-454.
Title:	Association of the DNMT3A -448A>G polymorphism with genetic susceptibility to colorectal cancer.
Author:	Zhao, Zhujiang\|Li, Can\|Song, Yunwei\|Wu, Qunying\|Qiao, Fengchang\|Fan, Hong
PMID:	22740930

19.
Journal:	Anticancer Res. 2013 Dec;33(12):5325-33.
Title:	Green tea polyphenol epigallocatechin 3-gallate, contributes to the degradation of DNMT3A and HDAC3 in HCT 116 human colon cancer cells.
Author:	Moseley, Vondina R\|Morris, Jay\|Knackstedt, Rebecca W\|Wargovich, Michael J
PMID:	24324066

20.
Journal:	Biomed Rep. 2013 Jul;1(4):664-668.
Title:	DNMT3A -448A>G polymorphism and the risk for hepatocellular carcinoma.
Author:	Zhao, Chengcheng\|Yan, Feng\|Wu, Huazhang\|Qiao, Fengchang\|Qiu, Xuemei\|Fan, Hong
PMID:	24649006

21.
Journal:	PLoS One. 2014 Oct 1;9(10):e108708.
Title:	MiR-410 is overexpressed in liver and colorectal tumors and enhances tumor cell growth by silencing FHL1 via a direct/indirect mechanism.
Author:	Wang, Yu\|Fu, Jie\|Jiang, Mengmeng\|Zhang, Xiaoai\|Cheng, Long\|Xu, Xiaojie\|Fan, Zhongyi\|Zhang, Jing\|Ye, Qinong\|Song, Haifeng
PMID:	25272045

22.
Journal:	Front Oncol. 2014 May 1;4:80.
Title:	DNA methyltransferases: a novel target for prevention and therapy.
Author:	Subramaniam, Dharmalingam\|Thombre, Ravi\|Dhar, Animesh\|Anant, Shrikant
PMID:	24822169

23.
Journal:	Hum Mol Genet. 2014 Apr 15;23(8):2043-54.
Title:	Altered regulation of DNA ligase IV activity by aberrant promoter DNA methylation and gene amplification in colorectal cancer.
Author:	Kuhmann, Christine\|Li, Carmen\|Kloor, Matthias\|Salou, Mariam\|Weigel, Christoph\|Schmidt, Christopher R\|Ng, Linda W C\|Tsui, Wendy W Y\|Leung, Suet Y\|Yuen, Siu T\|Becker, Natalia\|Weichenhan, Dieter\|Plass, Christoph\|Schmezer, Peter\|Chan, Tsun L\|Popanda, Odilia
PMID:	24282031

24.
Journal:	Gene. 2014 Aug 10;546(2):263-70.
Title:	Mutation and expression analysis of the IDH1, IDH2, DNMT3A, and MYD88 genes in colorectal cancer.
Author:	Li, Wen-Liang\|Xiao, Mei-Sheng\|Zhang, Deng-Feng\|Yu, Dandan\|Yang, Run-Xiang\|Li, Xiao-Yan\|Yao, Yong-Gang
PMID:	24887488

25.
Journal:	Oncogene. 2015 Apr 2;34(14):1822-30.
Title:	Inhibition of intestinal tumor formation by deletion of the DNA methyltransferase 3a.
Author:	Weis, B\|Schmidt, J\|Maamar, H\|Raj, A\|Lin, H\|Toth, C\|Riedmann, K\|Raddatz, G\|Seitz, H-K\|Ho, A D\|Lyko, F\|Linhart, H G
PMID:	24837369

26.
Journal:	Genet Mol Res. 2015 Apr 17;14(2):3640-9.
Title:	DNMT3A -448A>G polymorphism and cancer risk: a meta-analysis.
Author:	Liu, C H\|Tao, T\|Jiang, L\|Xu, B\|Zhang, L\|Lu, K\|Zhang, X W\|Chen, S Q\|Liu, D C\|Chen, M
PMID:	25966133

27.
Journal:	PLoS One. 2015 Jul 2;10(7):e0131699.
Title:	Cell Free DNA of Tumor Origin Induces a 'Metastatic' Expression Profile in HT-29 Cancer Cell Line.
Author:	Furi, Istvan\|Kalmar, Alexandra\|Wichmann, Barnabas\|Spisak, Sandor\|Scholler, Andrea\|Bartak, Barbara\|Tulassay, Zsolt\|Molnar, Bela
PMID:	26133168

28.
Journal:	Cell Biochem Funct. 2015 Oct;33(7):427-33.
Title:	Association of DNA methyltransferases expression with global and gene-specific DNA methylation in colorectal cancer cells.
Author:	Sarabi, Mostafa Moradi\|Naghibalhossaini, Fakhraddin
PMID:	26416384

29.
Journal:	Int J Oncol. 2015 Dec;47(6):2264-75.
Title:	Radiation-induced modulation of immunogenic genes in tumor cells is regulated by both histone deacetylases and DNA methyltransferases.
Author:	Cacan, Ercan\|Greer, Susanna F\|Garnett-Benson, Charlie
PMID:	26458736

30.
Journal:	Elife. 2016 Apr 14;5.
Title:	A long non-coding RNA targets microRNA miR-34a to regulate colon cancer stem cell asymmetric division.
Author:	Wang, Lihua\|Bu, Pengcheng\|Ai, Yiwei\|Srinivasan, Tara\|Chen, Huanhuan Joyce\|Xiang, Kun\|Lipkin, Steven M\|Shen, Xiling
PMID:	27077950

31.
Journal:	Oncol Rep. 2016 Nov;36(5):2705-2714.
Title:	Expression of DNA methyltransferases and target microRNAs in human tissue samples related to sporadic colorectal cancer.
Author:	Huang, Chao\|Liu, Hong\|Gong, Xiu-Li\|Wu, Liyun\|Wen, Bin
PMID:	27666771

32.
Journal:	Clin Epigenetics. 2017 Jan 19;9:4.
Title:	The immunomodulatory anticancer agent, RRx-001, induces an interferon response through epigenetic induction of viral mimicry.
Author:	Zhao, Hongjuan\|Ning, Shoucheng\|Nolley, Rosalie\|Scicinski, Jan\|Oronsky, Bryan\|Knox, Susan J\|Peehl, Donna M
PMID:	28149332

33.
Journal:	Cell Death Differ. 2017 Dec;24(12):2199-2209.
Title:	miR-148a inhibits colitis and colitis-associated tumorigenesis in mice.
Author:	Zhu, Yahui\|Gu, Li\|Li, Yajun\|Lin, Xi\|Shen, Hongxing\|Cui, Kaisa\|Chen, Li\|Zhou, Feng\|Zhao, Qiu\|Zhang, Jinxiang\|Zhong, Bo\|Prochownik, Edward\|Li, Youjun
PMID:	28960206

34.
Journal:	Biochem Biophys Res Commun. 2017 Aug 19;490(2):317-323.
Title:	PART-1 functions as a competitive endogenous RNA for promoting tumor progression by sponging miR-143 in colorectal cancer.
Author:	Hu, Yongbo\|Ma, Zhen\|He, Yiming\|Liu, Wei\|Su, Yu\|Tang, Zongbin
PMID:	28619512

35.
Journal:	Cancer Lett. 2017 Aug 28;402:110-116.
Title:	Epigenetic effects of inhibition of heat shock protein 90 (HSP90) in human pancreatic and colon cancer.
Author:	Nagaraju, Ganji Purnachandra\|Wu, Christina\|Merchant, Neha\|Chen, Zhengjia\|Lesinski, Gregory B\|El-Rayes, Bassel F
PMID:	28583846

36.
Journal:	J Med Chem. 2017 Jun 8;60(11):4665-4679.
Title:	Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells.
Author:	Halby, Ludovic\|Menon, Yoann\|Rilova, Elodie\|Pechalrieu, Dany\|Masson, Veronique\|Faux, Celine\|Bouhlel, Mohamed Amine\|David-Cordonnier, Marie-Helene\|Novosad, Natacha\|Aussagues, Yannick\|Samson, Arnaud\|Lacroix, Laurent\|Ausseil, Frederic\|Fleury, Laurence\|Guianva
PMID:	28463515

37.
Journal:	Oncol Rep. 2017 Mar;37(3):1637-1645.
Title:	Effect of evodiamine and berberine on the interaction between DNMTs and target microRNAs during malignant transformation of the colon by TGF-beta1.
Author:	Huang, Chao\|Liu, Hong\|Gong, Xiu-Li\|Wu, Li-Yun\|Wen, Bin
PMID:	28098901

38.
Journal:	Biomed Pharmacother. 2018 Feb;98:433-439.
Title:	LncRNA HIF1A-AS2 positively affects the progression and EMT formation of colorectal cancer through regulating miR-129-5p and DNMT3A.
Author:	Lin, Jinguan\|Shi, Zhaohui\|Yu, Zhiyuan\|He, Zhe
PMID:	29278853

39.
Journal:	Biomed Pharmacother. 2018 May;101:94-99.
Title:	The impact of polyunsaturated fatty acids on DNA methylation and expression of DNMTs in human colorectal cancer cells.
Author:	Sarabi, Mostafa Moradi\|Naghibalhossaini, Fakhraddin
PMID:	29477476

40.
Journal:	PLoS One. 2018 Apr 11;13(4):e0194098.
Title:	Germline mutations in candidate predisposition genes in individuals with cutaneous melanoma and at least two independent additional primary cancers.
Author:	Pritchard, Antonia L\|Johansson, Peter A\|Nathan, Vaishnavi\|Howlie, Madeleine\|Symmons, Judith\|Palmer, Jane M\|Hayward, Nicholas K
PMID:	29641532

41.
Journal:	Clin Epigenetics. 2018 Apr 25;10:60.
Title:	Adipose tissue inflammation and VDR expression and methylation in colorectal cancer.
Author:	Castellano-Castillo, Daniel\|Morcillo, Sonsoles\|Clemente-Postigo, Mercedes\|Crujeiras, Ana Belen\|Fernandez-Garcia, Jose Carlos\|Torres, Esperanza\|Tinahones, Francisco Jose\|Macias-Gonzalez, Manuel
PMID:	29719581

42.
Journal:	Mol Ther. 2018 Jul 5;26(7):1828-1839.
Title:	Heat Shock Factor 1 Epigenetically Stimulates Glutaminase-1-Dependent mTOR Activation to Promote Colorectal Carcinogenesis.
Author:	Li, Jiaqiu\|Song, Ping\|Jiang, Tingting\|Dai, Dongjun\|Wang, Hanying\|Sun, Jie\|Zhu, Liyuan\|Xu, Wenxia\|Feng, Lifeng\|Shin, Vivian Y\|Morrison, Helen\|Wang, Xian\|Jin, Hongchuan
PMID:	29730197

43.
Journal:	Oncotarget. 2018 May 22;9(39):25557-25571.
Title:	Genome wide DNA differential methylation regions in colorectal cancer patients in relation to blood related family members, obese and non-obese controls - a preliminary report.
Author:	Shiao, S Pamela K\|Xiao, Haiyan\|Dong, Lixin\|Wang, Xiaoling\|Liu, Kebin\|She, Jinxiong\|Shi, Huidong
PMID:	29876008