Primary Site >> Stomach Cancer

Gene >> DNMT1

Journal: Oncol Rep. 2001 Sep-Oct;8(5):1085-9.
Title: DNA methylation status of hMLH1, p16(INK4a), and CDH1 is not associated with mRNA expression levels of DNA methyltransferase and DNA demethylase in gastric carcinomas.
Author: Oue, N|Kuraoka, K|Kuniyasu, H|Yokozaki, H|Wakikawa, A|Matsusaki, K|Yasui, W
PMID: 11496321
Journal: Int J Cancer. 2001 Jan 15;91(2):205-12.
Title: DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers.
Author: Kanai, Y|Ushijima, S|Kondo, Y|Nakanishi, Y|Hirohashi, S
PMID: 11146446
Journal: Chin Med J (Engl). 2004 Jan;117(1):99-103.
Title: 5-Aza-2'-deoxycitydine induces demethylation and up-regulates transcription of p16INK4A gene in human gastric cancer cell lines.
Author: Fang, Jing-yuan|Yang, Li|Zhu, Hong-yin|Chen, Ying-xuan|Lu, Juan|Lu, Rong|Cheng, Zhong-hua|Xiao, Shu-dong
PMID: 14733783
Journal: Am J Pathol. 2004 Feb;164(2):689-99.
Title: Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers.
Author: Etoh, Tsuyoshi|Kanai, Yae|Ushijima, Saori|Nakagawa, Tohru|Nakanishi, Yukihiro|Sasako, Mitsuru|Kitano, Seigo|Hirohashi, Setsuo
PMID: 14742272
Journal: Oncol Rep. 2004 Sep;12(3):527-31.
Title: Inhibition of DNA methyltransferase by antisense oligodeoxynucleotide modifies cell characteristics in gastric cancer cell lines.
Author: Saikawa, Yoshiro|Kubota, Tetsuro|Maeda, Shingo|Otani, Yoshihide|Kumai, Koichiro|Kitajima, Masaki
PMID: 15289832
Journal: Oncogene. 2004 Nov 25;23(55):8876-86.
Title: Epigenetic inactivation of class II transactivator (CIITA) is associated with the absence of interferon-gamma-induced HLA-DR expression in colorectal and gastric cancer cells.
Author: Satoh, Ayumi|Toyota, Minoru|Ikeda, Hideyuki|Morimoto, Yoshikazu|Akino, Kimishige|Mita, Hiroaki|Suzuki, Hiromu|Sasaki, Yasushi|Kanaseki, Takayuki|Takamura, Yukio|Soejima, Hidenobu|Urano, Takeshi|Yanagihara, Kazuyoshi|Endo, Takao|Hinoda, Yuji|Fujita, Masahi
PMID: 15467734
Journal: World J Gastroenterol. 2004 Dec 1;10(23):3394-8.
Title: Expression of Dnmt1, demethylase, MeCP2 and methylation of tumor-related genes in human gastric cancer.
Author: Fang, Jing-Yuan|Cheng, Zhong-Hua|Chen, Ying-Xuan|Lu, Rong|Yang, Li|Zhu, Hong-Yin|Lu, Lun-Gen
PMID: 15526354
Journal: Zhonghua Yi Xue Za Zhi. 2006 Jun 13;86(22):1534-9.
Title: [Effects of pshRNA-DNMT1 on the proliferation and apoptosis of gastric cancer: experiments in vitro and in vivo].
Author: Chen, Dao-rong|Wang, Pi-long|Huang, Ai-long|Zhang, Bing-qiang
PMID: 16854279
Journal: Ai Zheng. 2006 Mar;25(3):308-14.
Title: [Effects of dnmt1 gene silencing on cell cycle, proliferation, and apoptosis of gastric cancer cell line AGS].
Author: Chen, Dao-Rong|Wang, Pi-Long|Huang, Ai-Long|Zhang, Bing-Qiang
PMID: 16536984
Journal: Dig Dis Sci. 2008 Aug;53(8):2083-9.
Title: The expression and clinical significance of DNA methyltransferase proteins in human gastric cancer.
Author: Ding, Wen-Jin|Fang, Jing-Yuan|Chen, Xiao-Yu|Peng, Yan-Shen
PMID: 18253830
Journal: Zhonghua Zhong Liu Za Zhi. 2008 May;30(5):361-4.
Title: [Relationship between Runx3 gene expression and its DNA methylation in gastric cancer].
Author: Gao, Nan|Chen, Wei-Chang|Cen, Jian-Nong
PMID: 18953836
Journal: Br J Cancer. 2009 Feb 24;100(4):663-9.
Title: DLEC1 is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancers.
Author: Ying, J|Poon, F F|Yu, J|Geng, H|Wong, A H Y|Qiu, G-H|Goh, H K|Rha, S Y|Tian, L|Chan, A T C|Sung, J J Y|Tao, Q
PMID: 19156137
Journal: Cancer Res. 2009 Apr 1;69(7):2766-74.
Title: Activation of DNA methyltransferase 1 by EBV latent membrane protein 2A leads to promoter hypermethylation of PTEN gene in gastric carcinoma.
Author: Hino, Rumi|Uozaki, Hiroshi|Murakami, Noriko|Ushiku, Tetsuo|Shinozaki, Aya|Ishikawa, Shumpei|Morikawa, Teppei|Nakaya, Takeo|Sakatani, Takashi|Takada, Kenzo|Fukayama, Masashi
PMID: 19339266
Journal: J Urol. 2009 Aug;182(2):756-61.
Title: DNMT1 silencing affects locus specific DNA methylation and increases prostate cancer derived PC3 cell invasiveness.
Author: Yaqinuddin, Ahmed|Qureshi, Sohail A|Qazi, Romena|Farooq, Salman|Abbas, Farhat
PMID: 19539327
Journal: Asian Pac J Cancer Prev. 2009;10(6):1177-82.
Title: Lack of effects of single nucleotide polymorphisms of the DNA methyltransferase 1 gene on gastric cancer in Iranian patients: a case control study.
Author: Khatami, Fatemeh|Noorinayer, Babak|Ghiasi, Somayeh|Mohebi, Reza|Hashemi, Mohhamad|Zali, Mohammad Reza
PMID: 20192608
Journal: Pathol Int. 2010 May;60(5):337-50.
Title: Epstein-Barr virus and gastric carcinoma.
Author: Fukayama, Masashi
PMID: 20518883
Journal: Zhonghua Bing Li Xue Za Zhi. 2010 Dec;39(12):798-803.
Title: [Clinicopathologic features and protein expression study of Epstein-Barr virus-associated gastric carcinoma in Guangzhou].
Author: Han, Jing|He, Dan|Feng, Zhi-Ying|Ding, Yun-Gang|Shao, Chun-Kui
PMID: 21215093
Journal: J Gastroenterol Hepatol. 2010 Apr;25(4):823-31.
Title: Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer.
Author: Chen, Weichang|Gao, Nan|Shen, Yuling|Cen, Jian-Nong
PMID: 20492341
Journal: Eur J Cancer. 2011 Aug;47(12):1817-25.
Title: DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer.
Author: Mutze, Kathrin|Langer, Rupert|Schumacher, Felix|Becker, Karen|Ott, Katja|Novotny, Alexander|Hapfelmeier, Alexander|Hofler, Heinz|Keller, Gisela
PMID: 21458988
Journal: Gut. 2011 Nov;60(11):1544-53.
Title: Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell 'stemness' via the bone morphogenetic protein pathway.
Author: Kodach, Liudmila L|Jacobs, Rutger J|Voorneveld, Philip W|Wildenberg, Manon E|Verspaget, Henricus W|van Wezel, Tom|Morreau, Hans|Hommes, Daniel W|Peppelenbosch, Maikel P|van den Brink, Gijs R|Hardwick, James C H
PMID: 21551187
Journal: Mol Med Rep. 2011 Nov-Dec;4(6):1139-43.
Title: Clinical significance of the expression of DNA methyltransferase proteins in gastric cancer.
Author: Yang, Jian|Wei, Xiaowei|Wu, Qingxiang|Xu, Zhi|Gu, Dongying|Jin, Yan|Shen, Yue|Huang, Huaying|Fan, Hong|Chen, Jinfei
PMID: 21887466
Journal: Pathol Res Pract. 2011 Sep 15;207(9):529-37.
Title: Epstein-Barr virus-associated gastric carcinoma.
Author: Fukayama, Masashi|Ushiku, Tetsuo
PMID: 21944426
Journal: Med Oncol. 2012 Dec;29(4):2701-9.
Title: MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in gastric cancer.
Author: Zhu, Akao|Xia, Jiazeng|Zuo, Junbo|Jin, Shimao|Zhou, Hong|Yao, Lubin|Huang, Hongyu|Han, Zhijun
PMID: 22167392
Journal: Lab Invest. 2012 Jul;92(7):1033-44.
Title: Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers.
Author: Yun, Jiyeon|Song, Sang-Hyun|Park, Jinah|Kim, Hwang-Phill|Yoon, Young-Kwang|Lee, Kyung-Hun|Han, Sae-Won|Oh, Do-Youn|Im, Seock-Ah|Bang, Yung-Jue|Kim, Tae-You
PMID: 22508389
Journal: Dig Dis Sci. 2012 Aug;57(8):2055-62.
Title: Correlation of epigenetic aberrance with STAT3 signaling pathway in gastric carcinogenesis.
Author: Gao, Fuli|Lv, Ying|Zhu, Yinxin|Chen, Min|Shen, Shanshan|Cao, Jun|Zou, Xiaoping
PMID: 22562532
Journal: Oncol Rep. 2012 Aug;28(2):545-52.
Title: 5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status.
Author: Liu, Juan|Zhang, Yan|Xie, Yi-Shan|Wang, Fu-Liang|Zhang, Li-Jun|Deng, Tao|Luo, He-Sheng
PMID: 22664909
Journal: Histol Histopathol. 2012 Oct;27(10):1271-82.
Title: Promoter methylation of tumor-related genes in gastric carcinogenesis.
Author: Zhao, Chenghai|Bu, Xianmin
PMID: 22936446
Journal: Int J Mol Sci. 2012;13(7):8364-78.
Title: Risk-association of DNA methyltransferases polymorphisms with gastric cancer in the Southern Chinese population.
Author: Yang, Xue-Xi|He, Xuan-Qiu|Li, Fen-Xia|Wu, Ying-Song|Gao, Yang|Li, Ming
PMID: 22942708
Journal: PLoS One. 2012;7(9):e46058.
Title: Polymorphisms of the DNA methyltransferase 1 associated with reduced risks of Helicobacter pylori infection and increased risks of gastric atrophy.
Author: Jiang, Jing|Jia, Zhifang|Cao, Donghui|Jin, Mei-Shan|Kong, Fei|Suo, Jian|Cao, Xueyuan
PMID: 23049933
Journal: Nihon Rinsho. 2012 Oct;70(10):1715-9.
Title: [Epstein-Barr virus and gastric carcinoma].
Author: Fukayama, Masashi
PMID: 23198550
Journal: Biochem Biophys Res Commun. 2013 Jan 4;430(1):250-5.
Title: The DNA methyltransferase inhibitor zebularine induces mitochondria-mediated apoptosis in gastric cancer cells in vitro and in vivo.
Author: Tan, Wei|Zhou, Wei|Yu, Hong-gang|Luo, He-Sheng|Shen, Lei
PMID: 23167995
Journal: Clin Cancer Res. 2013 Oct 15;19(20):5602-12.
Title: miR-200b and miR-200c as prognostic factors and mediators of gastric cancer cell progression.
Author: Tang, Hailin|Deng, Min|Tang, Yunyun|Xie, Xinhua|Guo, Jiaoli|Kong, Yanan|Ye, Feng|Su, Qi|Xie, Xiaoming
PMID: 23995857
Journal: Exp Ther Med. 2013 Mar;5(3):735-741.
Title: Reactivation of the homeotic tumor suppressor gene CDX2 by 5-aza-2'-deoxycytidine-induced demethylation inhibits cell proliferation and induces caspase-independent apoptosis in gastric cancer cells.
Author: Zhang, Jian-Feng|Zhang, Jian-Guo|Kuai, Xiao-Ling|Zhang, Hong|Jiang, Wei|Ding, Wei-Feng|Li, Zeng-Li|Zhu, Hui-Jun|Mao, Zhen-Biao
PMID: 23408490
Journal: Mol Cells. 2013 Apr;35(4):313-9.
Title: MicroRNA-148a can regulate runt-related transcription factor 3 gene expression via modulation of DNA methyltransferase 1 in gastric cancer.
Author: Zuo, Junbo|Xia, Jiazeng|Ju, Feng|Yan, Jiang|Zhu, Akao|Jin, Shimao|Shan, Ting|Zhou, Hong
PMID: 23549984
Journal: Med Oncol. 2014 Mar;31(3):879.
Title: MiR-148a regulates MEG3 in gastric cancer by targeting DNA methyltransferase 1.
Author: Yan, Jiang|Guo, Xiaoqiang|Xia, Jiazeng|Shan, Tin|Gu, Chen|Liang, Zheng|Zhao, Wei|Jin, Shimao
PMID: 24515776
Journal: PLoS One. 2014 Mar 25;9(3):e92911.
Title: A novel functional TagSNP Rs7560488 in the DNMT3A1 promoter is associated with susceptibility to gastric cancer by modulating promoter activity.
Author: Wu, Huazhang|Zhang, Kun|Gong, Pihai|Qiao, Fengchang|Wang, Ling|Cui, He|Sui, Xinyuan|Gao, Jifan|Fan, Hong
PMID: 24667323
Journal: Mol Biol Rep. 2014 Sep;41(9):5693-700.
Title: Decreased miR-30b-5p expression by DNMT1 methylation regulation involved in gastric cancer metastasis.
Author: Qiao, Fengchang|Zhang, Kun|Gong, Pihai|Wang, Ling|Hu, Jiaojiao|Lu, Sen|Fan, Hong
PMID: 24913034
Journal: Int J Oncol. 2014 Dec;45(6):2576-86.
Title: Epigenetic silencing of miRNA-9 is correlated with promoter-proximal CpG island hypermethylation in gastric cancer in vitro and in vivo.
Author: Li, Yan|Xu, Zhong|Li, Bo|Zhang, Zhengzheng|Luo, Hongchun|Wang, Yuanhu|Lu, Zhizhong|Wu, Xiaoling
PMID: 25270964
Journal: PLoS One. 2014 Oct 22;9(10):e109235.
Title: Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population.
Author: Chang, Shen-Chih|Chang, Po-Yin|Butler, Brendan|Goldstein, Binh Y|Mu, Lina|Cai, Lin|You, Nai-Chieh Y|Baecker, Aileen|Yu, Shun-Zhang|Heber, David|Lu, Qing-Yi|Li, Liming|Greenland, Sander|Zhang, Zuo-Feng
PMID: 25337902
Journal: Cell Oncol (Dordr). 2014 Dec;37(6):455-61.
Title: Somatic mutations of amino acid metabolism-related genes in gastric and colorectal cancers and their regional heterogeneity--a short report.
Author: Oh, Hye Rim|An, Chang Hyeok|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 25450519
Journal: Adv Med Sci. 2015 Mar;60(1):50-7.
Title: Increased DNA methyltransferase 1 protein expression correlates significantly with intestinal histological type and gender in gastric carcinomas.
Author: Ksiaa, Feryel|Ziadi, Sonia|Dhiab, Myriam Ben|Gacem, Riadh Ben|Trimeche, Mounir
PMID: 25461380
Journal: Cancer Lett. 2015 Apr 10;359(2):198-205.
Title: DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression.
Author: Ning, Xianghong|Shi, Zhendong|Liu, Xi|Zhang, Anling|Han, Lei|Jiang, Kui|Kang, Chunsheng|Zhang, Qingyu
PMID: 25595591
Journal: Diagn Pathol. 2015 Jun 2;10:59.
Title: Association between human papillomavirus and Epstein - Barr virus DNA and gene promoter methylation of RB1 and CDH1 in the cervical lesions: a transversal study.
Author: McCormick, Thais M|Canedo, Nathalie H S|Furtado, Yara L|Silveira, Filomena A|de Lima, Roberto J|Rosman, Andrea D F|Almeida Filho, Gutemberg L|Carvalho, Maria da Gloria da C
PMID: 26032781
Journal: Oncotarget. 2015 May 20;6(14):12603-24.
Title: Quercetin-induced apoptosis prevents EBV infection.
Author: Lee, Minjung|Son, Myoungki|Ryu, Eunhyun|Shin, Yu Su|Kim, Jong Gwang|Kang, Byung Woog|Cho, Hyosun|Kang, Hyojeung
PMID: 26059439
Journal: J Transl Med. 2015 Aug 4;13:250.
Title: Decreased long noncoding RNA SPRY4-IT1 contributing to gastric cancer cell metastasis partly via affecting epithelial-mesenchymal transition.
Author: Xie, Min|Nie, Feng-qi|Sun, Ming|Xia, Rui|Liu, Yan-wen|Zhou, Peng|De, Wei|Liu, Xiang-hua
PMID: 26238992
Journal: Asian Pac J Cancer Prev. 2016;17(6):3015-20.
Title: DNMT3B -149 C>T and -579 G>T Polymorphisms and Risk of Gastric and Colorectal Cancer: a Meta-analysis.
Author: Khoram-Abadi, Khadijeh Mirzaee|Forat-Yazdi, Mohammad|Kheirandish, Shahnaz|Saeidi, Nasim|Zarezade, Zeinab|Mehrabi, Nahid|Neamatzadeh, Hossein
PMID: 27356727
Journal: Cancer Res. 2016 Nov 1;76(21):6299-6310.
Title: LncRNA HOXA11-AS Promotes Proliferation and Invasion of Gastric Cancer by Scaffolding the Chromatin Modification Factors PRC2, LSD1, and DNMT1.
Author: Sun, Ming|Nie, Fengqi|Wang, Yunfei|Zhang, Zhihong|Hou, Jiakai|He, Dandan|Xie, Min|Xu, Lin|De, Wei|Wang, Zhaoxia|Wang, Jun
PMID: 27651312
Journal: Dis Markers. 2016;2016:8578064.
Title: Polymorphisms of the DNA Methyltransferase 1 Gene Predict Survival of Gastric Cancer Patients Receiving Tumorectomy.
Author: Jia, Zhifang|Wu, Xing|Cao, Donghui|Wang, Chuan|You, Lili|Jin, Meishan|Wen, Simin|Cao, Xueyuan|Jiang, Jing
PMID: 27087738
Journal: Exp Ther Med. 2017 Feb;13(2):745-750.
Title: Casticin inhibits the activity of transcription factor Sp1 and the methylation of RECK in MGC803 gastric cancer cells.
Author: Yang, Fan|He, Kefei|Huang, Li|Zhang, Lingyan|Liu, Aixue|Zhang, Jiren
PMID: 28352361
Journal: Mol Cancer. 2017 Apr 26;16(1):82.
Title: Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer.
Author: Liu, Zhili|Chen, Zhenyao|Fan, Ruihua|Jiang, Bin|Chen, Xin|Chen, Qinnan|Nie, Fengqi|Lu, Kaihua|Sun, Ming
PMID: 28441948
Journal: Biomed Res Int. 2017;2017:3971259.
Title: A Meta-Analysis of the Association between DNMT1 Polymorphisms and Cancer Risk.
Author: Li, Hao|Liu, Jing-Wei|Sun, Li-Ping|Yuan, Yuan
PMID: 28473984
Journal: Cancer Immunol Res. 2017 Oct;5(10):885-897.
Title: Tumor-Associated Macrophages Promote Epigenetic Silencing of Gelsolin through DNA Methyltransferase 1 in Gastric Cancer Cells.
Author: Wang, Hao-Chen|Chen, Chin-Wang|Yang, Chia-Lung|Tsai, I-Min|Hou, Ya-Chin|Chen, Chang-Jung|Shan, Yan-Shen
PMID: 28835422
Journal: Oncotarget. 2017 Oct 4;8(56):96396-96408.
Title: DNMT1 overexpression predicting gastric carcinogenesis, subsequent progression and prognosis: a meta and bioinformatic analysis.
Author: Ma, Tianmiao|Li, Hao|Sun, Mingjun|Yuan, Yuan|Sun, Li-Ping
PMID: 29221215
Journal: J Cell Biochem. 2018 Feb;119(2):2440-2449.
Title: Procaine is a specific DNA methylation inhibitor with anti-tumor effect for human gastric cancer.
Author: Li, Yong-Chao|Wang, Yun|Li, Dan-Dan|Zhang, Ying|Zhao, Tian-Cheng|Li, Chang-Feng
PMID: 28926119
Journal: Biochem Biophys Res Commun. 2018 Mar 4;497(2):527-534.
Title: Knockdown of long non-coding RNA MAP3K20 antisense RNA 1 inhibits gastric cancer growth through epigenetically regulating miR-375.
Author: Quan, Yongsheng|Zhang, Yan|Lin, Wei|Shen, Zhaohua|Wu, Shuai|Zhu, Changxin|Wang, Xiaoyan
PMID: 29428732
Journal: Oncol Lett. 2018 Apr;15(4):4944-4950.
Title: miR-148a suppresses cell invasion and migration in gastric cancer by targeting DNA methyltransferase 1.
Author: Shi, Huaijie|Chen, Xiaojing|Jiang, Hao|Wang, Xujie|Yu, Hao|Sun, Pijiang|Sui, Xin
PMID: 29541249
Journal: J Cancer Res Ther. 2018;14(Supplement):S237-S242.
Title: Effect of lenalidomide on the human gastric cancer cell line SGC7901/vincristine Notch signaling.
Author: Ding, Wanjun|Zeng, Tao|Tao, Weiping|Ge, Wei|Deng, Junjian|Lei, Hongbo|Xiao, Yong|Liao, Fei
PMID: 29578180
Journal: Oncotarget. 2018 Apr 6;9(26):18386-18399.
Title: Comprehensive analysis of aberrantly expressed lncRNAs and construction of ceRNA network in gastric cancer.
Author: Arun, Kanagaraj|Arunkumar, Ganesan|Bennet, Duraisamy|Chandramohan, Servarayan Murugesan|Murugan, Avaniyapuram Kannan|Munirajan, Arasambattu Kannan
PMID: 29719612
Journal: Future Oncol. 2018 Jul;14(17):1731-1739.
Title: Association of five genetic variations in DNMT1 and DNMT3A with gastric cancer in a Chinese population.
Author: Zhou, Jin|Wang, Zhibing|Zhang, Lei|Gu, Yuanyuan|Ma, Yong|Li, Xiangcheng
PMID: 29956566
Journal: Biomol Ther (Seoul). 2018 Sep 3. pii: biomolther.2018.061.
Title: Combinatorial Antitumor Activity of Oxaliplatin with Epigenetic Modifying Agents, 5-Aza-CdR and FK228, in Human Gastric Cancer Cells.
Author: Park, Jong Kook|Seo, Jung Seon|Lee, Suk Kyeong|Chan, Kenneth K|Kuh, Hyo-Jeong
PMID: 30173503
Journal: Epigenomics. 2018 Oct 16.
Title: DNA methyltransferases and gastric cancer: insight into targeted therapy.
Author: Fattahi, Sadegh|Golpour, Monireh|Amjadi-Moheb, Fatemeh|Sharifi-Pasandi, Marzieh|Khodadadi, Parastesh|Pilehchian-Langroudi, Maryam|Ashrafi, Gholam Hossein|Akhavan-Niaki, Haleh
PMID: 30325215