Primary Site >> Stomach Cancer
Gene >> DNMT1
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Ref: DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers. PMID: 11146446 Ref: DNA methylation status of hMLH1, p16(INK4a), and CDH1 is not associated with mRNA expression levels of DNA methyltransferase and DNA demethylase in gastric carcinomas. PMID: 11496321 |
Ref: 5-Aza-2'-deoxycitydine induces demethylation and up-regulates transcription of p16INK4A gene in human gastric cancer cell lines. PMID: 14733783 Ref: Increased DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG islands in gastric cancers. PMID: 14742272 Ref: Inhibition of DNA methyltransferase by antisense oligodeoxynucleotide modifies cell characteristics in gastric cancer cell lines. PMID: 15289832 Ref: Epigenetic inactivation of class II transactivator (CIITA) is associated with the absence of interferon-gamma-induced HLA-DR expression in colorectal and gastric cancer cells. PMID: 15467734 Ref: Expression of Dnmt1, demethylase, MeCP2 and methylation of tumor-related genes in human gastric cancer. PMID: 15526354 |
Ref: [Effects of dnmt1 gene silencing on cell cycle, proliferation, and apoptosis of gastric cancer cell line AGS]. PMID: 16536984 Ref: [Effects of pshRNA-DNMT1 on the proliferation and apoptosis of gastric cancer: experiments in vitro and in vivo]. PMID: 16854279 |
Ref: The expression and clinical significance of DNA methyltransferase proteins in human gastric cancer. PMID: 18253830 Ref: [Relationship between Runx3 gene expression and its DNA methylation in gastric cancer]. PMID: 18953836 |
Ref: DLEC1 is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancers. PMID: 19156137 Ref: Activation of DNA methyltransferase 1 by EBV latent membrane protein 2A leads to promoter hypermethylation of PTEN gene in gastric carcinoma. PMID: 19339266 Ref: DNMT1 silencing affects locus specific DNA methylation and increases prostate cancer derived PC3 cell invasiveness. PMID: 19539327 Ref: Lack of effects of single nucleotide polymorphisms of the DNA methyltransferase 1 gene on gastric cancer in Iranian patients: a case control study. PMID: 20192608 |
Ref: Hypermethylation downregulates Runx3 gene expression and its restoration suppresses gastric epithelial cell growth by inducing p27 and caspase3 in human gastric cancer. PMID: 20492341 Ref: Epstein-Barr virus and gastric carcinoma. PMID: 20518883 Ref: [Clinicopathologic features and protein expression study of Epstein-Barr virus-associated gastric carcinoma in Guangzhou]. PMID: 21215093 |
Ref: DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer. PMID: 21458988 Ref: Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell 'stemness' via the bone morphogenetic protein pathway. PMID: 21551187 Ref: Clinical significance of the expression of DNA methyltransferase proteins in gastric cancer. PMID: 21887466 Ref: Epstein-Barr virus-associated gastric carcinoma. PMID: 21944426 |
Ref: MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in gastric cancer. PMID: 22167392 Ref: Gene silencing of EREG mediated by DNA methylation and histone modification in human gastric cancers. PMID: 22508389 Ref: Correlation of epigenetic aberrance with STAT3 signaling pathway in gastric carcinogenesis. PMID: 22562532 Ref: 5-Aza-2'-deoxycytidine induces cytotoxicity in BGC-823 cells via DNA methyltransferase 1 and 3a independent of p53 status. PMID: 22664909 Ref: Promoter methylation of tumor-related genes in gastric carcinogenesis. PMID: 22936446 Ref: Risk-association of DNA methyltransferases polymorphisms with gastric cancer in the Southern Chinese population. PMID: 22942708 Ref: Polymorphisms of the DNA methyltransferase 1 associated with reduced risks of Helicobacter pylori infection and increased risks of gastric atrophy. PMID: 23049933 Ref: [Epstein-Barr virus and gastric carcinoma]. PMID: 23198550 |
Ref: The DNA methyltransferase inhibitor zebularine induces mitochondria-mediated apoptosis in gastric cancer cells in vitro and in vivo. PMID: 23167995 Ref: Reactivation of the homeotic tumor suppressor gene CDX2 by 5-aza-2'-deoxycytidine-induced demethylation inhibits cell proliferation and induces caspase-independent apoptosis in gastric cancer cells. PMID: 23408490 Ref: MicroRNA-148a can regulate runt-related transcription factor 3 gene expression via modulation of DNA methyltransferase 1 in gastric cancer. PMID: 23549984 Ref: miR-200b and miR-200c as prognostic factors and mediators of gastric cancer cell progression. PMID: 23995857 |
Ref: MiR-148a regulates MEG3 in gastric cancer by targeting DNA methyltransferase 1. PMID: 24515776 Ref: A novel functional TagSNP Rs7560488 in the DNMT3A1 promoter is associated with susceptibility to gastric cancer by modulating promoter activity. PMID: 24667323 Ref: Decreased miR-30b-5p expression by DNMT1 methylation regulation involved in gastric cancer metastasis. PMID: 24913034 Ref: Epigenetic silencing of miRNA-9 is correlated with promoter-proximal CpG island hypermethylation in gastric cancer in vitro and in vivo. PMID: 25270964 Ref: Single nucleotide polymorphisms of one-carbon metabolism and cancers of the esophagus, stomach, and liver in a Chinese population. PMID: 25337902 Ref: Somatic mutations of amino acid metabolism-related genes in gastric and colorectal cancers and their regional heterogeneity--a short report. PMID: 25450519 |
Ref: Increased DNA methyltransferase 1 protein expression correlates significantly with intestinal histological type and gender in gastric carcinomas. PMID: 25461380 Ref: DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression. PMID: 25595591 Ref: Association between human papillomavirus and Epstein - Barr virus DNA and gene promoter methylation of RB1 and CDH1 in the cervical lesions: a transversal study. PMID: 26032781 Ref: Quercetin-induced apoptosis prevents EBV infection. PMID: 26059439 Ref: Decreased long noncoding RNA SPRY4-IT1 contributing to gastric cancer cell metastasis partly via affecting epithelial-mesenchymal transition. PMID: 26238992 |
Ref: Polymorphisms of the DNA Methyltransferase 1 Gene Predict Survival of Gastric Cancer Patients Receiving Tumorectomy. PMID: 27087738 Ref: DNMT3B -149 C>T and -579 G>T Polymorphisms and Risk of Gastric and Colorectal Cancer: a Meta-analysis. PMID: 27356727 Ref: LncRNA HOXA11-AS Promotes Proliferation and Invasion of Gastric Cancer by Scaffolding the Chromatin Modification Factors PRC2, LSD1, and DNMT1. PMID: 27651312 |
Ref: Casticin inhibits the activity of transcription factor Sp1 and the methylation of RECK in MGC803 gastric cancer cells. PMID: 28352361 Ref: Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer. PMID: 28441948 Ref: A Meta-Analysis of the Association between DNMT1 Polymorphisms and Cancer Risk. PMID: 28473984 Ref: Tumor-Associated Macrophages Promote Epigenetic Silencing of Gelsolin through DNA Methyltransferase 1 in Gastric Cancer Cells. PMID: 28835422 Ref: DNMT1 overexpression predicting gastric carcinogenesis, subsequent progression and prognosis: a meta and bioinformatic analysis. PMID: 29221215 |
Ref: Procaine is a specific DNA methylation inhibitor with anti-tumor effect for human gastric cancer. PMID: 28926119 Ref: Knockdown of long non-coding RNA MAP3K20 antisense RNA 1 inhibits gastric cancer growth through epigenetically regulating miR-375. PMID: 29428732 Ref: miR-148a suppresses cell invasion and migration in gastric cancer by targeting DNA methyltransferase 1. PMID: 29541249 Ref: Effect of lenalidomide on the human gastric cancer cell line SGC7901/vincristine Notch signaling. PMID: 29578180 Ref: Comprehensive analysis of aberrantly expressed lncRNAs and construction of ceRNA network in gastric cancer. PMID: 29719612 Ref: Association of five genetic variations in DNMT1 and DNMT3A with gastric cancer in a Chinese population. PMID: 29956566 Ref: Combinatorial Antitumor Activity of Oxaliplatin with Epigenetic Modifying Agents, 5-Aza-CdR and FK228, in Human Gastric Cancer Cells. PMID: 30173503 Ref: DNA methyltransferases and gastric cancer: insight into targeted therapy. PMID: 30325215 |