Primary Site >> Colorectal Cancer
Gene >> DNMT1
| 1. | |||||||||||
| Journal: | Cancer Res. 1999 May 15;59(10):2302-6. | ||||||||||
| Title: | CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression. | ||||||||||
| Author: | Eads, C A|Danenberg, K D|Kawakami, K|Saltz, L B|Danenberg, P V|Laird, P W | ||||||||||
| PMID: | 10344733 | ||||||||||
| 2. | |||||||||||
| Journal: | Cancer Res. 1999 Aug 15;59(16):3855-60. | ||||||||||
| Title: | Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis. | ||||||||||
| Author: | De Marzo, A M|Marchi, V L|Yang, E S|Veeraswamy, R|Lin, X|Nelson, W G | ||||||||||
| PMID: | 10463569 | ||||||||||
| 3. | |||||||||||
| Journal: | Nature. 2000 Apr 27;404(6781):1003-7. | ||||||||||
| Title: | CpG methylation is maintained in human cancer cells lacking DNMT1. | ||||||||||
| Author: | Rhee, I|Jair, K W|Yen, R W|Lengauer, C|Herman, J G|Kinzler, K W|Vogelstein, B|Baylin, S B|Schuebel, K E | ||||||||||
| PMID: | 10801130 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 2000 Jul 15;60(14):3965-70. | ||||||||||
| Title: | Dnmt1N/+ reduces the net growth rate and multiplicity of intestinal adenomas in C57BL/6-multiple intestinal neoplasia (Min)/+ mice independently of p53 but demonstrates strong synergy with the modifier of Min 1(AKR) resistance allele. | ||||||||||
| Author: | Cormier, R T|Dove, W F | ||||||||||
| PMID: | 10919675 | ||||||||||
| 5. | |||||||||||
| Journal: | Int J Cancer. 2001 Jan 15;91(2):205-12. | ||||||||||
| Title: | DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers. | ||||||||||
| Author: | Kanai, Y|Ushijima, S|Kondo, Y|Nakanishi, Y|Hirohashi, S | ||||||||||
| PMID: | 11146446 | ||||||||||
| 6. | |||||||||||
| Journal: | Nature. 2002 Apr 4;416(6880):552-6. | ||||||||||
| Title: | DNMT1 and DNMT3b cooperate to silence genes in human cancer cells. | ||||||||||
| Author: | Rhee, Ina|Bachman, Kurtis E|Park, Ben Ho|Jair, Kam-Wing|Yen, Ray-Whay Chiu|Schuebel, Kornel E|Cui, Hengmi|Feinberg, Andrew P|Lengauer, Christoph|Kinzler, Kenneth W|Baylin, Stephen B|Vogelstein, Bert | ||||||||||
| PMID: | 11932749 | ||||||||||
| 7. | |||||||||||
| Journal: | Cancer Res. 2002 Nov 15;62(22):6442-6. | ||||||||||
| Title: | Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2. | ||||||||||
| Author: | Cui, Hengmi|Onyango, Patrick|Brandenburg, Sheri|Wu, Yiqian|Hsieh, Chih-Lin|Feinberg, Andrew P | ||||||||||
| PMID: | 12438232 | ||||||||||
| 8. | |||||||||||
| Journal: | J Biol Chem. 2003 Mar 7;278(10):8238-43. Epub 2002 Dec 10. | ||||||||||
| Title: | A potent cell-active allosteric inhibitor of murine DNA cytosine C5 methyltransferase. | ||||||||||
| Author: | Flynn, James|Fang, Jing-Yuan|Mikovits, Judy A|Reich, Norbert O | ||||||||||
| PMID: | 12477724 | ||||||||||
| 9. | |||||||||||
| Journal: | Nat Genet. 2003 Jan;33(1):61-5. Epub 2002 Dec 23. | ||||||||||
| Title: | DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells. | ||||||||||
| Author: | Robert, Marie-France|Morin, Steves|Beaulieu, Normand|Gauthier, France|Chute, Ian C|Barsalou, Annie|MacLeod, A Robert | ||||||||||
| PMID: | 12496760 | ||||||||||
| 10. | |||||||||||
| Journal: | Carcinogenesis. 2003 Jan;24(1):17-24. | ||||||||||
| Title: | Human DNA methyltransferase gene DNMT1 is regulated by the APC pathway. | ||||||||||
| Author: | Campbell, Paul M|Szyf, Moshe | ||||||||||
| PMID: | 12538344 | ||||||||||
| 11. | |||||||||||
| Journal: | Carcinogenesis. 2003 Jan;24(1):39-45. | ||||||||||
| Title: | Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice. | ||||||||||
| Author: | Trasler, Jacquetta|Deng, Liyuan|Melnyk, Stepan|Pogribny, Igor|Hiou-Tim, Francois|Sibani, Sahar|Oakes, Christopher|Li, En|James, S Jill|Rozen, Rima | ||||||||||
| PMID: | 12538347 | ||||||||||
| 12. | |||||||||||
| Journal: | Curr Med Chem Anticancer Agents. 2003 May;3(3):187-99. | ||||||||||
| Title: | The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells. | ||||||||||
| Author: | Zhu, Wei-Guo|Otterson, Gregory A | ||||||||||
| PMID: | 12769777 | ||||||||||
| 13. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7818-23. Epub 2003 Jun 16. | ||||||||||
| Title: | Epigenetic inactivation of CHFR in human tumors. | ||||||||||
| Author: | Toyota, Minoru|Sasaki, Yasushi|Satoh, Ayumi|Ogi, Kazuhiro|Kikuchi, Takefumi|Suzuki, Hiromu|Mita, Hiroaki|Tanaka, Nobuyuki|Itoh, Fumio|Issa, Jean-Pierre J|Jair, Kam-Wing|Schuebel, Kornel E|Imai, Kohzoh|Tokino, Takashi | ||||||||||
| PMID: | 12810945 | ||||||||||
| 14. | |||||||||||
| Journal: | Cancer Biol Ther. 2003 May-Jun;2(3):259-63. | ||||||||||
| Title: | Mitoxantrone mediates demethylation and reexpression of cyclin d2, estrogen receptor and 14.3.3sigma in breast cancer cells. | ||||||||||
| Author: | Parker, Belinda S|Cutts, Suzanne M|Nudelman, Abraham|Rephaeli, Ada|Phillips, Don R|Sukumar, Saraswati | ||||||||||
| PMID: | 12878861 | ||||||||||
| 15. | |||||||||||
| Journal: | Hum Mol Genet. 2003 Sep 1;12(17):2209-19. Epub 2003 Jul 15. | ||||||||||
| Title: | Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases. | ||||||||||
| Author: | Paz, Maria F|Wei, Susan|Cigudosa, Juan C|Rodriguez-Perales, Sandra|Peinado, Miguel A|Huang, Tim Hui-Ming|Esteller, Manel | ||||||||||
| PMID: | 12915469 | ||||||||||
| 16. | |||||||||||
| Journal: | Cancer Res. 2003 Oct 15;63(20):6579-82. | ||||||||||
| Title: | p53-mediated repression of DNA methyltransferase 1 expression by specific DNA binding. | ||||||||||
| Author: | Peterson, Erica J|Bogler, Oliver|Taylor, Shirley M | ||||||||||
| PMID: | 14583449 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Res. 2003 Nov 15;63(22):7563-70. | ||||||||||
| Title: | Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines. | ||||||||||
| Author: | Fang, Ming Zhu|Wang, Yimin|Ai, Ni|Hou, Zhe|Sun, Yi|Lu, Hong|Welsh, William|Yang, Chung S | ||||||||||
| PMID: | 14633667 | ||||||||||
| 18. | |||||||||||
| Journal: | Zhonghua Yi Xue Za Zhi. 2004 Feb 17;84(4):312-7. | ||||||||||
| Title: | [Regulation of histone acetylation on the expression of cell cycle-associated genes in human colon cancer cell lines]. | ||||||||||
| Author: | Chen, Ying-xuan|Fang, Jing-yuan|Lu, Juan|Qiu, De-kai | ||||||||||
| PMID: | 15059516 | ||||||||||
| 19. | |||||||||||
| Journal: | Nat Genet. 2004 Jun;36(6):582-4. Epub 2004 May 23. | ||||||||||
| Title: | CpG island hypermethylation is maintained in human colorectal cancer cells after RNAi-mediated depletion of DNMT1. | ||||||||||
| Author: | Ting, Angela H|Jair, Kam-wing|Suzuki, Hiromu|Yen, Ray-Whay Chiu|Baylin, Stephen B|Schuebel, Kornel E | ||||||||||
| PMID: | 15156141 | ||||||||||
| 20. | |||||||||||
| Journal: | Zhonghua Yi Xue Za Zhi. 2004 Jun 17;84(12):1014-7. | ||||||||||
| Title: | [Effect of eukaryotic expression plasmid DNA methyltransferase gene on methylation status and transcription level of DNA mismatch repair genes in human colon cancer cell line]. | ||||||||||
| Author: | Lu, Rong|Fang, Jing-yuan|Zhu, Hong-yin|Chen, Ying-xuan|Cheng, Zhong-hua|Li, En-ling | ||||||||||
| PMID: | 15312538 | ||||||||||
| 21. | |||||||||||
| Journal: | Mol Pharmacol. 2004 Dec;66(6):1415-20. Epub 2004 Aug 31. | ||||||||||
| Title: | Doxorubicin inhibits DNMT1, resulting in conditional apoptosis. | ||||||||||
| Author: | Yokochi, Tomoki|Robertson, Keith D | ||||||||||
| PMID: | 15340041 | ||||||||||
| 22. | |||||||||||
| Journal: | World J Gastroenterol. 2004 Dec 1;10(23):3441-54. | ||||||||||
| Title: | Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis. | ||||||||||
| Author: | Xu, Xiao-Li|Yu, Jian|Zhang, Hong-Yu|Sun, Meng-Hong|Gu, Jun|Du, Xiang|Shi, Da-Ren|Wang, Peng|Yang, Zhen-Hua|Zhu, Jing-De | ||||||||||
| PMID: | 15526363 | ||||||||||
| 23. | |||||||||||
| Journal: | J Pharmacol Exp Ther. 2005 Feb;312(2):525-36. Epub 2004 Nov 16. | ||||||||||
| Title: | 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms. | ||||||||||
| Author: | Schneider-Stock, Regine|Diab-Assef, Mona|Rohrbeck, Astrid|Foltzer-Jourdainne, Charlotte|Boltze, Carsten|Hartig, Roland|Schonfeld, Peter|Roessner, Albert|Gali-Muhtasib, Hala | ||||||||||
| PMID: | 15547111 | ||||||||||
| 24. | |||||||||||
| Journal: | Cancer Res. 2005 May 1;65(9):3624-32. | ||||||||||
| Title: | Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathway. | ||||||||||
| Author: | McCabe, Michael T|Davis, Joanne N|Day, Mark L | ||||||||||
| PMID: | 15867357 | ||||||||||
| 25. | |||||||||||
| Journal: | Biochem Pharmacol. 2005 Jul 1;70(1):121-33. | ||||||||||
| Title: | Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells. | ||||||||||
| Author: | Ben-Kasus, Tsipi|Ben-Zvi, Zvi|Marquez, Victor E|Kelley, James A|Agbaria, Riad | ||||||||||
| PMID: | 15885659 | ||||||||||
| 26. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13580-5. | ||||||||||
| Title: | Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis. | ||||||||||
| Author: | Yamada, Yasuhiro|Jackson-Grusby, Laurie|Linhart, Heinz|Meissner, Alex|Eden, Amir|Lin, Haijiang|Jaenisch, Rudolf | ||||||||||
| PMID: | 16174748 | ||||||||||
| 27. | |||||||||||
| Journal: | Cancer Res. 2005 Oct 1;65(19):8635-9. | ||||||||||
| Title: | Genetic disruption of cytosine DNA methyltransferase enzymes induces chromosomal instability in human cancer cells. | ||||||||||
| Author: | Karpf, Adam R|Matsui, Sei-ichi | ||||||||||
| PMID: | 16204030 | ||||||||||
| 28. | |||||||||||
| Journal: | J Biol Chem. 2005 Dec 9;280(49):40749-56. Epub 2005 Oct 17. | ||||||||||
| Title: | Procainamide is a specific inhibitor of DNA methyltransferase 1. | ||||||||||
| Author: | Lee, Byron H|Yegnasubramanian, Srinivasan|Lin, Xiaohui|Nelson, William G | ||||||||||
| PMID: | 16230360 | ||||||||||
| 29. | |||||||||||
| Journal: | Cancer Res. 2006 Jan 15;66(2):682-92. | ||||||||||
| Title: | De novo CpG island methylation in human cancer cells. | ||||||||||
| Author: | Jair, Kam-Wing|Bachman, Kurtis E|Suzuki, Hiromu|Ting, Angela H|Rhee, Ina|Yen, Ray-Whay Chiu|Baylin, Stephen B|Schuebel, Kornel E | ||||||||||
| PMID: | 16423997 | ||||||||||
| 30. | |||||||||||
| Journal: | Cancer Res. 2006 Jan 15;66(2):729-35. | ||||||||||
| Title: | Differential requirement for DNA methyltransferase 1 in maintaining human cancer cell gene promoter hypermethylation. | ||||||||||
| Author: | Ting, Angela H|Jair, Kam-wing|Schuebel, Kornel E|Baylin, Stephen B | ||||||||||
| PMID: | 16424002 | ||||||||||
| 31. | |||||||||||
| Journal: | Cancer Lett. 2006 Feb 20;233(1):124-30. | ||||||||||
| Title: | Regulation of hMSH2 and hMLH1 expression in the human colon cancer cell line SW1116 by DNA methyltransferase 1. | ||||||||||
| Author: | Fang, Jing Yuan|Lu, Rong|Mikovits, Judy A|Cheng, Zhong Hua|Zhu, Hong Yin|Chen, Ying Xuan | ||||||||||
| PMID: | 16473673 | ||||||||||
| 32. | |||||||||||
| Journal: | Oncogene. 2006 Aug 17;25(36):4986-97. Epub 2006 Mar 27. | ||||||||||
| Title: | Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis. | ||||||||||
| Author: | Wendt, M K|Johanesen, P A|Kang-Decker, N|Binion, D G|Shah, V|Dwinell, M B | ||||||||||
| PMID: | 16568088 | ||||||||||
| 33. | |||||||||||
| Journal: | Oncogene. 2006 Nov 2;25(52):6975-85. Epub 2006 May 22. | ||||||||||
| Title: | Epigenetic regulation of X-linked cancer/germline antigen genes by DNMT1 and DNMT3b. | ||||||||||
| Author: | James, S R|Link, P A|Karpf, A R | ||||||||||
| PMID: | 16715135 | ||||||||||
| 34. | |||||||||||
| Journal: | J Biol Chem. 2006 Aug 4;281(31):22062-72. Epub 2006 May 30. | ||||||||||
| Title: | Role of DNA methyltransferases in regulation of human ribosomal RNA gene transcription. | ||||||||||
| Author: | Majumder, Sarmila|Ghoshal, Kalpana|Datta, Jharna|Smith, David Spencer|Bai, Shoumei|Jacob, Samson T | ||||||||||
| PMID: | 16735507 | ||||||||||
| 35. | |||||||||||
| Journal: | Zhonghua Zhong Liu Za Zhi. 2006 Aug;28(8):564-7. | ||||||||||
| Title: | [The effect of PKC-delta inhibitor Rottlerin on human colon cancer cell line SW1116 and its mechanism]. | ||||||||||
| Author: | Chen, Zhao-fei|Fang, Jing-yuan|Weng, Yu-rong|Sun, Dan-feng|Wang, Xia|Lu, Rong | ||||||||||
| PMID: | 17236547 | ||||||||||
| 36. | |||||||||||
| Journal: | Cancer Lett. 2007 Feb 8;246(1-2):313-7. | ||||||||||
| Title: | Trichostatin A down-regulate DNA methyltransferase 1 in Jurkat T cells. | ||||||||||
| Author: | Januchowski, Radoslaw|Dabrowski, Mikolaj|Ofori, Harold|Jagodzinski, Pawel P | ||||||||||
| PMID: | 16624484 | ||||||||||
| 37. | |||||||||||
| Journal: | Int J Colorectal Dis. 2007 Jun;22(6):661-6. Epub 2006 Nov 9. | ||||||||||
| Title: | Expression of human DNA methyltransferase 1 in colorectal cancer tissues and their corresponding distant normal tissues. | ||||||||||
| Author: | Zhu, Yi-Min|Huang, Qiong|Lin, Jie|Hu, Yu|Chen, Jian|Lai, Mao-De | ||||||||||
| PMID: | 17093909 | ||||||||||
| 38. | |||||||||||
| Journal: | J Biol Chem. 2007 Apr 20;282(16):12249-59. Epub 2007 Feb 16. | ||||||||||
| Title: | Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells. | ||||||||||
| Author: | Lu, Rong|Wang, Xia|Chen, Zhao-Fei|Sun, Dan-Feng|Tian, Xiao-Qing|Fang, Jing-Yuan | ||||||||||
| PMID: | 17307743 | ||||||||||
| 39. | |||||||||||
| Journal: | Nat Genet. 2007 Mar;39(3):391-6. Epub 2007 Feb 18. | ||||||||||
| Title: | Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells. | ||||||||||
| Author: | Chen, Taiping|Hevi, Sarah|Gay, Frederique|Tsujimoto, Naomi|He, Timothy|Zhang, Bailin|Ueda, Yoshihide|Li, En | ||||||||||
| PMID: | 17322882 | ||||||||||
| 40. | |||||||||||
| Journal: | J Cell Physiol. 2007 Oct;213(1):65-9. | ||||||||||
| Title: | Epigenetic inactivation of the metastasis suppressor RECK enhances invasion of human colon cancer cells. | ||||||||||
| Author: | Cho, Chun-Yu|Wang, Jui-Ho|Chang, Hui-Chiu|Chang, Chong-Keng|Hung, Wen-Chun | ||||||||||
| PMID: | 17443689 | ||||||||||
| 41. | |||||||||||
| Journal: | Mol Carcinog. 2007 Sep;46(9):766-72. | ||||||||||
| Title: | Progressive up-regulation of genes encoding DNA methyltransferases in the colorectal adenoma-carcinoma sequence. | ||||||||||
| Author: | Schmidt, Wolfgang M|Sedivy, Roland|Forstner, Birgit|Steger, Gunther G|Zochbauer-Muller, Sabine|Mader, Robert M | ||||||||||
| PMID: | 17538945 | ||||||||||
| 42. | |||||||||||
| Journal: | Int J Cancer. 2007 Nov 15;121(10):2192-7. | ||||||||||
| Title: | Association of the SUV39H1 histone methyltransferase with the DNA methyltransferase 1 at mRNA expression level in primary colorectal cancer. | ||||||||||
| Author: | Kang, Mi Yeon|Lee, Bo Bin|Kim, Young-Ho|Chang, Dong Kyoung|Kyu Park, Seo|Chun, Ho-Kyung|Song, Sang Yong|Park, Joobae|Kim, Duk-Hwan | ||||||||||
| PMID: | 17657744 | ||||||||||
| 43. | |||||||||||
| Journal: | Cancer Biol Ther. 2007 Aug;6(8):1284-8. Epub 2007 May 24. | ||||||||||
| Title: | DNA methylation regulates MicroRNA expression. | ||||||||||
| Author: | Han, Liangfeng|Witmer, P Dane|Casey, Emily|Valle, David|Sukumar, Saraswati | ||||||||||
| PMID: | 17660710 | ||||||||||
| 44. | |||||||||||
| Journal: | Cancer Res. 2007 Dec 15;67(24):11481-6. | ||||||||||
| Title: | Discovery of epigenetically silenced genes by methylated DNA immunoprecipitation in colon cancer cells. | ||||||||||
| Author: | Jacinto, Filipe V|Ballestar, Esteban|Ropero, Santiago|Esteller, Manel | ||||||||||
| PMID: | 18089774 | ||||||||||
| 45. | |||||||||||
| Journal: | FASEB J. 2008 Jun;22(6):1981-92. | ||||||||||
| Title: | 15-Lipoxygenase-1 transcriptional silencing by DNA methyltransferase-1 independently of DNA methylation. | ||||||||||
| Author: | Zuo, Xiangsheng|Shen, Lanlan|Issa, Jean-Pierre|Moy, Ofir|Morris, Jeffrey S|Lippman, Scott M|Shureiqi, Imad | ||||||||||
| PMID: | 18198215 | ||||||||||
| 46. | |||||||||||
| Journal: | Oncogene. 2008 Jun 5;27(25):3615-23. | ||||||||||
| Title: | p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage. | ||||||||||
| Author: | Jiemjit, A|Fandy, T E|Carraway, H|Bailey, K A|Baylin, S|Herman, J G|Gore, S D | ||||||||||
| PMID: | 18223691 | ||||||||||
| 47. | |||||||||||
| Journal: | Cancer. 2008 Apr 15;112(8):1699-707. | ||||||||||
| Title: | Association of interindividual differences in p14ARF promoter methylation with single nucleotide polymorphism in primary colorectal cancer. | ||||||||||
| Author: | Kang, Mi Yeon|Lee, Bo Bin|Ji, Yong Ick|Jung, Eun Hyun|Chun, Ho-Kyung|Song, Sang Yong|Park, Seong-Eun|Park, Joobae|Kim, Duk-Hwan | ||||||||||
| PMID: | 18327804 | ||||||||||
| 48. | |||||||||||
| Journal: | Mol Cell Biol. 2008 May;28(10):3219-35. | ||||||||||
| Title: | Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter. | ||||||||||
| Author: | Wu, Li-Peng|Wang, Xi|Li, Lian|Zhao, Ying|Lu, Shaoli|Yu, Yu|Zhou, Wen|Liu, Xiangyu|Yang, Jing|Zheng, Zhixin|Zhang, Hui|Feng, Jingnan|Yang, Yang|Wang, Haiying|Zhu, Wei-Guo | ||||||||||
| PMID: | 18332107 | ||||||||||
| 49. | |||||||||||
| Journal: | Br J Cancer. 2008 Jun 3;98(11):1810-9. | ||||||||||
| Title: | SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response. | ||||||||||
| Author: | Cheetham, S|Tang, M J|Mesak, F|Kennecke, H|Owen, D|Tai, I T | ||||||||||
| PMID: | 18458674 | ||||||||||
| 50. | |||||||||||
| Journal: | Mol Cancer Res. 2008 Dec;6(12):1841-51. | ||||||||||
| Title: | DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells. | ||||||||||
| Author: | McGough, Jon M|Yang, Dafeng|Huang, Shuang|Georgi, David|Hewitt, Stephen M|Rocken, Christoph|Tanzer, Marc|Ebert, Matthias P A|Liu, Kebin | ||||||||||
| PMID: | 19074829 | ||||||||||
| 51. | |||||||||||
| Journal: | Biochem J. 2009 Jan 1;417(1):379-89. | ||||||||||
| Title: | Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3. | ||||||||||
| Author: | Thangaraju, Muthusamy|Carswell, Kristina N|Prasad, Puttur D|Ganapathy, Vadivel | ||||||||||
| PMID: | 18789002 | ||||||||||
| 52. | |||||||||||
| Journal: | Br J Cancer. 2009 Feb 24;100(4):663-9. | ||||||||||
| Title: | DLEC1 is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancers. | ||||||||||
| Author: | Ying, J|Poon, F F|Yu, J|Geng, H|Wong, A H Y|Qiu, G-H|Goh, H K|Rha, S Y|Tian, L|Chan, A T C|Sung, J J Y|Tao, Q | ||||||||||
| PMID: | 19156137 | ||||||||||
| 53. | |||||||||||
| Journal: | Life Sci. 2009 Feb 27;84(9-10):311-20. | ||||||||||
| Title: | Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2'-deoxycytidine. | ||||||||||
| Author: | Deng, Tao|Zhang, Yan | ||||||||||
| PMID: | 19159630 | ||||||||||
| 54. | |||||||||||
| Journal: | Int J Colorectal Dis. 2009 Jun;24(6):629-39. | ||||||||||
| Title: | Combined inhibition of Dnmt and mTOR signaling inhibits formation and growth of colorectal cancer. | ||||||||||
| Author: | Zhang, Yan-Jie|Zhao, Shu-Liang|Tian, Xiao-Qing|Sun, Dan-Feng|Xiong, Hua|Dai, Qiang|Li, Xiao-Qiang|Fang, Jing-Yuan | ||||||||||
| PMID: | 19229543 | ||||||||||
| 55. | |||||||||||
| Journal: | Int J Cancer. 2009 Oct 1;125(7):1626-39. | ||||||||||
| Title: | Down-regulation of HLA Class I and NKG2D ligands through a concerted action of MAPK and DNA methyltransferases in colorectal cancer cells. | ||||||||||
| Author: | Sers, Christine|Kuner, Ruprecht|Falk, Christine S|Lund, Per|Sueltmann, Holger|Braun, Monika|Buness, Andreas|Ruschhaupt, Markus|Conrad, Janine|Mang-Fatehi, Shila|Stelniec, Iwona|Krapfenbauer, Ulf|Poustka, Annemarie|Schafer, Reinhold | ||||||||||
| PMID: | 19569244 | ||||||||||
| 56. | |||||||||||
| Journal: | Toxicol Lett. 2009 Dec 15;191(2-3):158-66. | ||||||||||
| Title: | 5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats. | ||||||||||
| Author: | Tikoo, Kulbhushan|Ali, Idrish Yunus|Gupta, Jeena|Gupta, Chanchal | ||||||||||
| PMID: | 19723570 | ||||||||||
| 57. | |||||||||||
| Journal: | Cancer Res. 2009 Sep 15;69(18):7412-21. | ||||||||||
| Title: | DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer. | ||||||||||
| Author: | Jin, Bilian|Yao, Bing|Li, Jian-Liang|Fields, C Robert|Delmas, Amber L|Liu, Chen|Robertson, Keith D | ||||||||||
| PMID: | 19723660 | ||||||||||
| 58. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2009;10(6):1183-8. | ||||||||||
| Title: | Effects of amino acid substitution polymorphisms of two DNA methyltransferases on susceptibility to sporadic colorectal cancer. | ||||||||||
| Author: | Khatami, Fatemeh|Noorinayer, Babak|Mohebi, Seyed Reza|Ghiasi, Somayeh|Mohebi, Reza|Hashemi, Mohhamad|Zali, Mohammad Reza | ||||||||||
| PMID: | 20192566 | ||||||||||
| 59. | |||||||||||
| Journal: | Biochem Biophys Res Commun. 2010 Jan 1;391(1):449-54. | ||||||||||
| Title: | TSA-induced DNMT1 down-regulation represses hTERT expression via recruiting CTCF into demethylated core promoter region of hTERT in HCT116. | ||||||||||
| Author: | Choi, Jee-Hye|Min, Na Young|Park, Jina|Kim, Jin Hong|Park, Soo Hyun|Ko, Young Jong|Kang, Yoonsung|Moon, Young Joon|Rhee, Sangmyung|Ham, Seung Wook|Park, Ae Ja|Lee, Kwang-Ho | ||||||||||
| PMID: | 19914212 | ||||||||||
| 60. | |||||||||||
| Journal: | J Huazhong Univ Sci Technolog Med Sci. 2010 Feb;30(1):69-74. | ||||||||||
| Title: | Epigenetic regulation of the ERbeta gene on the estrogen signal transfection pathway in colon cancer cells. | ||||||||||
| Author: | Zhai, Ronglin|Wang, Guobin|Cai, Kailin|Tao, Kaixiong|Xu, Fei|Zhang, Wanli|Wang, Zhiyong | ||||||||||
| PMID: | 20155458 | ||||||||||
| 61. | |||||||||||
| Journal: | Int J Radiat Oncol Biol Phys. 2010 Apr;76(5):1512-9. | ||||||||||
| Title: | Impact of genomic methylation on radiation sensitivity of colorectal carcinoma. | ||||||||||
| Author: | Hofstetter, Barbara|Niemierko, Andrzej|Forrer, Christian|Benhattar, Jean|Albertini, Veronica|Pruschy, Martn|Bosman, Fred T|Catapano, Carlo V|Ciernik, I Frank | ||||||||||
| PMID: | 20338477 | ||||||||||
| 62. | |||||||||||
| Journal: | Mol Cancer Res. 2010 Apr;8(4):471-81. | ||||||||||
| Title: | Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6. | ||||||||||
| Author: | Foran, Eilis|Garrity-Park, Megan M|Mureau, Coralie|Newell, John|Smyrk, Thomas C|Limburg, Paul J|Egan, Laurence J | ||||||||||
| PMID: | 20354000 | ||||||||||
| 63. | |||||||||||
| Journal: | PLoS One. 2010 Apr 29;5(4):e10338. | ||||||||||
| Title: | HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors. | ||||||||||
| Author: | Ghoshal, Kalpana|Motiwala, Tasneem|Claus, Rainer|Yan, Pearlly|Kutay, Huban|Datta, Jharna|Majumder, Sarmila|Bai, Shoumei|Majumder, Arnab|Huang, Tim|Plass, Christoph|Jacob, Samson T | ||||||||||
| PMID: | 20454457 | ||||||||||
| 64. | |||||||||||
| Journal: | Epigenetics. 2010 Aug 16;5(6):547-56. Epub 2010 Aug 16. | ||||||||||
| Title: | Ischemia dysregulates DNA methyltransferases and p16INK4a methylation in human colorectal cancer cells. | ||||||||||
| Author: | Skowronski, Karolina|Dubey, Sonam|Rodenhiser, David|Coomber, Brenda | ||||||||||
| PMID: | 20543577 | ||||||||||
| 65. | |||||||||||
| Journal: | Oncogene. 2010 Oct 28;29(43):5775-84. | ||||||||||
| Title: | Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription. | ||||||||||
| Author: | Weber, B|Kimhi, S|Howard, G|Eden, A|Lyko, F | ||||||||||
| PMID: | 20562909 | ||||||||||
| 66. | |||||||||||
| Journal: | Digestion. 2010;82(3):179-86. | ||||||||||
| Title: | Increased expression of DNA methyltransferase-1 in non-neoplastic epithelium helps predict colorectal neoplasia risk in ulcerative colitis. | ||||||||||
| Author: | Fujii, Shigehiko|Katake, Yoshiki|Tanaka, Hiroyuki | ||||||||||
| PMID: | 20588031 | ||||||||||
| 67. | |||||||||||
| Journal: | Sci Signal. 2010 Nov 2;3(146):ra80. | ||||||||||
| Title: | DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination. | ||||||||||
| Author: | Du, Zhanwen|Song, Jing|Wang, Yong|Zhao, Yiqing|Guda, Kishore|Yang, Shuming|Kao, Hung-Ying|Xu, Yan|Willis, Joseph|Markowitz, Sanford D|Sedwick, David|Ewing, Robert M|Wang, Zhenghe | ||||||||||
| PMID: | 21045206 | ||||||||||
| 68. | |||||||||||
| Journal: | Sichuan Da Xue Xue Bao Yi Xue Ban. 2010 Nov;41(6):975-9. | ||||||||||
| Title: | [Effect and mechanism of DNMT inhibitor on the reversal of multidrug resistance in human colon cancer cell line sw620/L-OHP]. | ||||||||||
| Author: | Deng, Qian|Li, Zhi-ping|Huang, Chun-mei|Liu, Zhen|Zhong, Ren-ming|Li, Ai-jun|Bi, Feng|Tang, Qiu-lin | ||||||||||
| PMID: | 21265097 | ||||||||||
| 69. | |||||||||||
| Journal: | Int J Cancer. 2011 Feb 1;128(3):551-61. | ||||||||||
| Title: | DNMT3a plays a role in switches between doxorubicin-induced senescence and apoptosis of colorectal cancer cells. | ||||||||||
| Author: | Zhang, Yu|Gao, Yanyan|Zhang, Guoping|Huang, Shuyan|Dong, Zhixiong|Kong, Chenfei|Su, Dongmei|Du, Juan|Zhu, Shan|Liang, Qian|Zhang, Jianchao|Lu, Jun|Huang, Baiqu | ||||||||||
| PMID: | 20473858 | ||||||||||
| 70. | |||||||||||
| Journal: | Proc Nutr Soc. 2011 Feb;70(1):47-56. | ||||||||||
| Title: | Epigenetic modifications and human pathologies: cancer and CVD. | ||||||||||
| Author: | Duthie, Susan J | ||||||||||
| PMID: | 21067630 | ||||||||||
| 71. | |||||||||||
| Journal: | Clin Cancer Res. 2011 Feb 1;17(3):598-610. | ||||||||||
| Title: | Modulation of genetic and epigenetic biomarkers of colorectal cancer in humans by black raspberries: a phase I pilot study. | ||||||||||
| Author: | Wang, Li-Shu|Arnold, Mark|Huang, Yi-Wen|Sardo, Christine|Seguin, Claire|Martin, Edward|Huang, Tim H-M|Riedl, Ken|Schwartz, Steven|Frankel, Wendy|Pearl, Dennis|Xu, Yiqing|Winston, John 3rd|Yang, Guang-Yu|Stoner, Gary | ||||||||||
| PMID: | 21123457 | ||||||||||
| 72. | |||||||||||
| Journal: | PLoS One. 2011 Mar 7;6(3):e17388. | ||||||||||
| Title: | Azacytidine and decitabine induce gene-specific and non-random DNA demethylation in human cancer cell lines. | ||||||||||
| Author: | Hagemann, Sabine|Heil, Oliver|Lyko, Frank|Brueckner, Bodo | ||||||||||
| PMID: | 21408221 | ||||||||||
| 73. | |||||||||||
| Journal: | PLoS One. 2011 Apr 19;6(4):e18844. | ||||||||||
| Title: | Relationship between gene body DNA methylation and intragenic H3K9me3 and H3K36me3 chromatin marks. | ||||||||||
| Author: | Hahn, Maria A|Wu, Xiwei|Li, Arthur X|Hahn, Torsten|Pfeifer, Gerd P | ||||||||||
| PMID: | 21526191 | ||||||||||
| 74. | |||||||||||
| Journal: | Int J Mol Epidemiol Genet. 2011 Jan 1;2(1):1-8. Epub 2010 Nov 5. | ||||||||||
| Title: | Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations. | ||||||||||
| Author: | Curtin, Karen|Ulrich, Cornelia M|Samowitz, Wade S|Wolff, Roger K|Duggan, David J|Makar, Karen W|Caan, Bette J|Slattery, Martha L | ||||||||||
| PMID: | 21537397 | ||||||||||
| 75. | |||||||||||
| Journal: | Gut. 2011 Nov;60(11):1544-53. | ||||||||||
| Title: | Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell 'stemness' via the bone morphogenetic protein pathway. | ||||||||||
| Author: | Kodach, Liudmila L|Jacobs, Rutger J|Voorneveld, Philip W|Wildenberg, Manon E|Verspaget, Henricus W|van Wezel, Tom|Morreau, Hans|Hommes, Daniel W|Peppelenbosch, Maikel P|van den Brink, Gijs R|Hardwick, James C H | ||||||||||
| PMID: | 21551187 | ||||||||||
| 76. | |||||||||||
| Journal: | Carcinogenesis. 2011 Jul;32(7):1033-42. | ||||||||||
| Title: | MicroRNA-342 inhibits colorectal cancer cell proliferation and invasion by directly targeting DNA methyltransferase 1. | ||||||||||
| Author: | Wang, Hui|Wu, Jiangxue|Meng, Xiangqi|Ying, Xiaofang|Zuo, Yufang|Liu, Ranyi|Pan, Zhizhong|Kang, Tiebang|Huang, Wenlin | ||||||||||
| PMID: | 21565830 | ||||||||||
| 77. | |||||||||||
| Journal: | Hum Mol Genet. 2011 Aug 15;20(16):3241-55. | ||||||||||
| Title: | DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response. | ||||||||||
| Author: | Loughery, Jayne E P|Dunne, Philip D|O'Neill, Karla M|Meehan, Richard R|McDaid, Jennifer R|Walsh, Colum P | ||||||||||
| PMID: | 21636528 | ||||||||||
| 78. | |||||||||||
| Journal: | Nucleic Acids Res. 2011 Oct;39(19):e127. | ||||||||||
| Title: | Targeted bisulfite sequencing by solution hybrid selection and massively parallel sequencing. | ||||||||||
| Author: | Lee, Eun-Joon|Pei, Lirong|Srivastava, Gyan|Joshi, Trupti|Kushwaha, Garima|Choi, Jeong-Hyeon|Robertson, Keith D|Wang, Xinguo|Colbourne, John K|Zhang, Lu|Schroth, Gary P|Xu, Dong|Zhang, Kun|Shi, Huidong | ||||||||||
| PMID: | 21785137 | ||||||||||
| 79. | |||||||||||
| Journal: | J Antibiot (Tokyo). 2011 Sep;64(9):635-44. | ||||||||||
| Title: | Molecular basis for the actions of Hsp90 inhibitors and cancer therapy. | ||||||||||
| Author: | Yamaki, Hiroshi|Nakajima, Motowo|Shimotohno, Kumiko W|Tanaka, Nobuo | ||||||||||
| PMID: | 21811259 | ||||||||||
| 80. | |||||||||||
| Journal: | J Med Chem. 2011 Nov 10;54(21):7663-77. | ||||||||||
| Title: | Synthesis and biochemical evaluation of delta(2)-isoxazoline derivatives as DNA methyltransferase 1 inhibitors. | ||||||||||
| Author: | Castellano, Sabrina|Kuck, Dirk|Viviano, Monica|Yoo, Jakyung|Lopez-Vallejo, Fabian|Conti, Paola|Tamborini, Lucia|Pinto, Andrea|Medina-Franco, Jose L|Sbardella, Gianluca | ||||||||||
| PMID: | 21958292 | ||||||||||
| 81. | |||||||||||
| Journal: | Tumour Biol. 2012 Apr;33(2):403-12. | ||||||||||
| Title: | Epigenetic changes induced by oxidative stress in colorectal cancer cells: methylation of tumor suppressor RUNX3. | ||||||||||
| Author: | Kang, Kyoung Ah|Zhang, Rui|Kim, Gi Young|Bae, Suk Chul|Hyun, Jin Won | ||||||||||
| PMID: | 22274925 | ||||||||||
| 82. | |||||||||||
| Journal: | Nucleic Acids Res. 2012 May;40(10):4334-46. | ||||||||||
| Title: | DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes. | ||||||||||
| Author: | Clements, Eriko G|Mohammad, Helai P|Leadem, Benjamin R|Easwaran, Hariharan|Cai, Yi|Van Neste, Leander|Baylin, Stephen B | ||||||||||
| PMID: | 22278882 | ||||||||||
| 83. | |||||||||||
| Journal: | Cancer Biol Ther. 2012 May;13(7):542-52. | ||||||||||
| Title: | |||||||||||