Primary Site >> Colorectal Cancer

Gene >> DNMT1

Journal: Cancer Res. 1999 May 15;59(10):2302-6.
Title: CpG island hypermethylation in human colorectal tumors is not associated with DNA methyltransferase overexpression.
Author: Eads, C A|Danenberg, K D|Kawakami, K|Saltz, L B|Danenberg, P V|Laird, P W
PMID: 10344733
Journal: Cancer Res. 1999 Aug 15;59(16):3855-60.
Title: Abnormal regulation of DNA methyltransferase expression during colorectal carcinogenesis.
Author: De Marzo, A M|Marchi, V L|Yang, E S|Veeraswamy, R|Lin, X|Nelson, W G
PMID: 10463569
Journal: Nature. 2000 Apr 27;404(6781):1003-7.
Title: CpG methylation is maintained in human cancer cells lacking DNMT1.
Author: Rhee, I|Jair, K W|Yen, R W|Lengauer, C|Herman, J G|Kinzler, K W|Vogelstein, B|Baylin, S B|Schuebel, K E
PMID: 10801130
Journal: Cancer Res. 2000 Jul 15;60(14):3965-70.
Title: Dnmt1N/+ reduces the net growth rate and multiplicity of intestinal adenomas in C57BL/6-multiple intestinal neoplasia (Min)/+ mice independently of p53 but demonstrates strong synergy with the modifier of Min 1(AKR) resistance allele.
Author: Cormier, R T|Dove, W F
PMID: 10919675
Journal: Int J Cancer. 2001 Jan 15;91(2):205-12.
Title: DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers.
Author: Kanai, Y|Ushijima, S|Kondo, Y|Nakanishi, Y|Hirohashi, S
PMID: 11146446
Journal: Nature. 2002 Apr 4;416(6880):552-6.
Title: DNMT1 and DNMT3b cooperate to silence genes in human cancer cells.
Author: Rhee, Ina|Bachman, Kurtis E|Park, Ben Ho|Jair, Kam-Wing|Yen, Ray-Whay Chiu|Schuebel, Kornel E|Cui, Hengmi|Feinberg, Andrew P|Lengauer, Christoph|Kinzler, Kenneth W|Baylin, Stephen B|Vogelstein, Bert
PMID: 11932749
Journal: Cancer Res. 2002 Nov 15;62(22):6442-6.
Title: Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2.
Author: Cui, Hengmi|Onyango, Patrick|Brandenburg, Sheri|Wu, Yiqian|Hsieh, Chih-Lin|Feinberg, Andrew P
PMID: 12438232
Journal: J Biol Chem. 2003 Mar 7;278(10):8238-43. Epub 2002 Dec 10.
Title: A potent cell-active allosteric inhibitor of murine DNA cytosine C5 methyltransferase.
Author: Flynn, James|Fang, Jing-Yuan|Mikovits, Judy A|Reich, Norbert O
PMID: 12477724
Journal: Nat Genet. 2003 Jan;33(1):61-5. Epub 2002 Dec 23.
Title: DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells.
Author: Robert, Marie-France|Morin, Steves|Beaulieu, Normand|Gauthier, France|Chute, Ian C|Barsalou, Annie|MacLeod, A Robert
PMID: 12496760
Journal: Carcinogenesis. 2003 Jan;24(1):17-24.
Title: Human DNA methyltransferase gene DNMT1 is regulated by the APC pathway.
Author: Campbell, Paul M|Szyf, Moshe
PMID: 12538344
Journal: Carcinogenesis. 2003 Jan;24(1):39-45.
Title: Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice.
Author: Trasler, Jacquetta|Deng, Liyuan|Melnyk, Stepan|Pogribny, Igor|Hiou-Tim, Francois|Sibani, Sahar|Oakes, Christopher|Li, En|James, S Jill|Rozen, Rima
PMID: 12538347
Journal: Curr Med Chem Anticancer Agents. 2003 May;3(3):187-99.
Title: The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells.
Author: Zhu, Wei-Guo|Otterson, Gregory A
PMID: 12769777
Journal: Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7818-23. Epub 2003 Jun 16.
Title: Epigenetic inactivation of CHFR in human tumors.
Author: Toyota, Minoru|Sasaki, Yasushi|Satoh, Ayumi|Ogi, Kazuhiro|Kikuchi, Takefumi|Suzuki, Hiromu|Mita, Hiroaki|Tanaka, Nobuyuki|Itoh, Fumio|Issa, Jean-Pierre J|Jair, Kam-Wing|Schuebel, Kornel E|Imai, Kohzoh|Tokino, Takashi
PMID: 12810945
Journal: Cancer Biol Ther. 2003 May-Jun;2(3):259-63.
Title: Mitoxantrone mediates demethylation and reexpression of cyclin d2, estrogen receptor and 14.3.3sigma in breast cancer cells.
Author: Parker, Belinda S|Cutts, Suzanne M|Nudelman, Abraham|Rephaeli, Ada|Phillips, Don R|Sukumar, Saraswati
PMID: 12878861
Journal: Hum Mol Genet. 2003 Sep 1;12(17):2209-19. Epub 2003 Jul 15.
Title: Genetic unmasking of epigenetically silenced tumor suppressor genes in colon cancer cells deficient in DNA methyltransferases.
Author: Paz, Maria F|Wei, Susan|Cigudosa, Juan C|Rodriguez-Perales, Sandra|Peinado, Miguel A|Huang, Tim Hui-Ming|Esteller, Manel
PMID: 12915469
Journal: Cancer Res. 2003 Oct 15;63(20):6579-82.
Title: p53-mediated repression of DNA methyltransferase 1 expression by specific DNA binding.
Author: Peterson, Erica J|Bogler, Oliver|Taylor, Shirley M
PMID: 14583449
Journal: Cancer Res. 2003 Nov 15;63(22):7563-70.
Title: Tea polyphenol (-)-epigallocatechin-3-gallate inhibits DNA methyltransferase and reactivates methylation-silenced genes in cancer cell lines.
Author: Fang, Ming Zhu|Wang, Yimin|Ai, Ni|Hou, Zhe|Sun, Yi|Lu, Hong|Welsh, William|Yang, Chung S
PMID: 14633667
Journal: Zhonghua Yi Xue Za Zhi. 2004 Feb 17;84(4):312-7.
Title: [Regulation of histone acetylation on the expression of cell cycle-associated genes in human colon cancer cell lines].
Author: Chen, Ying-xuan|Fang, Jing-yuan|Lu, Juan|Qiu, De-kai
PMID: 15059516
Journal: Nat Genet. 2004 Jun;36(6):582-4. Epub 2004 May 23.
Title: CpG island hypermethylation is maintained in human colorectal cancer cells after RNAi-mediated depletion of DNMT1.
Author: Ting, Angela H|Jair, Kam-wing|Suzuki, Hiromu|Yen, Ray-Whay Chiu|Baylin, Stephen B|Schuebel, Kornel E
PMID: 15156141
Journal: Zhonghua Yi Xue Za Zhi. 2004 Jun 17;84(12):1014-7.
Title: [Effect of eukaryotic expression plasmid DNA methyltransferase gene on methylation status and transcription level of DNA mismatch repair genes in human colon cancer cell line].
Author: Lu, Rong|Fang, Jing-yuan|Zhu, Hong-yin|Chen, Ying-xuan|Cheng, Zhong-hua|Li, En-ling
PMID: 15312538
Journal: Mol Pharmacol. 2004 Dec;66(6):1415-20. Epub 2004 Aug 31.
Title: Doxorubicin inhibits DNMT1, resulting in conditional apoptosis.
Author: Yokochi, Tomoki|Robertson, Keith D
PMID: 15340041
Journal: World J Gastroenterol. 2004 Dec 1;10(23):3441-54.
Title: Methylation profile of the promoter CpG islands of 31 genes that may contribute to colorectal carcinogenesis.
Author: Xu, Xiao-Li|Yu, Jian|Zhang, Hong-Yu|Sun, Meng-Hong|Gu, Jun|Du, Xiang|Shi, Da-Ren|Wang, Peng|Yang, Zhen-Hua|Zhu, Jing-De
PMID: 15526363
Journal: J Pharmacol Exp Ther. 2005 Feb;312(2):525-36. Epub 2004 Nov 16.
Title: 5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms.
Author: Schneider-Stock, Regine|Diab-Assef, Mona|Rohrbeck, Astrid|Foltzer-Jourdainne, Charlotte|Boltze, Carsten|Hartig, Roland|Schonfeld, Peter|Roessner, Albert|Gali-Muhtasib, Hala
PMID: 15547111
Journal: Cancer Res. 2005 May 1;65(9):3624-32.
Title: Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathway.
Author: McCabe, Michael T|Davis, Joanne N|Day, Mark L
PMID: 15867357
Journal: Biochem Pharmacol. 2005 Jul 1;70(1):121-33.
Title: Metabolic activation of zebularine, a novel DNA methylation inhibitor, in human bladder carcinoma cells.
Author: Ben-Kasus, Tsipi|Ben-Zvi, Zvi|Marquez, Victor E|Kelley, James A|Agbaria, Riad
PMID: 15885659
Journal: Proc Natl Acad Sci U S A. 2005 Sep 20;102(38):13580-5.
Title: Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis.
Author: Yamada, Yasuhiro|Jackson-Grusby, Laurie|Linhart, Heinz|Meissner, Alex|Eden, Amir|Lin, Haijiang|Jaenisch, Rudolf
PMID: 16174748
Journal: Cancer Res. 2005 Oct 1;65(19):8635-9.
Title: Genetic disruption of cytosine DNA methyltransferase enzymes induces chromosomal instability in human cancer cells.
Author: Karpf, Adam R|Matsui, Sei-ichi
PMID: 16204030
Journal: J Biol Chem. 2005 Dec 9;280(49):40749-56. Epub 2005 Oct 17.
Title: Procainamide is a specific inhibitor of DNA methyltransferase 1.
Author: Lee, Byron H|Yegnasubramanian, Srinivasan|Lin, Xiaohui|Nelson, William G
PMID: 16230360
Journal: Cancer Res. 2006 Jan 15;66(2):682-92.
Title: De novo CpG island methylation in human cancer cells.
Author: Jair, Kam-Wing|Bachman, Kurtis E|Suzuki, Hiromu|Ting, Angela H|Rhee, Ina|Yen, Ray-Whay Chiu|Baylin, Stephen B|Schuebel, Kornel E
PMID: 16423997
Journal: Cancer Res. 2006 Jan 15;66(2):729-35.
Title: Differential requirement for DNA methyltransferase 1 in maintaining human cancer cell gene promoter hypermethylation.
Author: Ting, Angela H|Jair, Kam-wing|Schuebel, Kornel E|Baylin, Stephen B
PMID: 16424002
Journal: Cancer Lett. 2006 Feb 20;233(1):124-30.
Title: Regulation of hMSH2 and hMLH1 expression in the human colon cancer cell line SW1116 by DNA methyltransferase 1.
Author: Fang, Jing Yuan|Lu, Rong|Mikovits, Judy A|Cheng, Zhong Hua|Zhu, Hong Yin|Chen, Ying Xuan
PMID: 16473673
Journal: Oncogene. 2006 Aug 17;25(36):4986-97. Epub 2006 Mar 27.
Title: Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis.
Author: Wendt, M K|Johanesen, P A|Kang-Decker, N|Binion, D G|Shah, V|Dwinell, M B
PMID: 16568088
Journal: Oncogene. 2006 Nov 2;25(52):6975-85. Epub 2006 May 22.
Title: Epigenetic regulation of X-linked cancer/germline antigen genes by DNMT1 and DNMT3b.
Author: James, S R|Link, P A|Karpf, A R
PMID: 16715135
Journal: J Biol Chem. 2006 Aug 4;281(31):22062-72. Epub 2006 May 30.
Title: Role of DNA methyltransferases in regulation of human ribosomal RNA gene transcription.
Author: Majumder, Sarmila|Ghoshal, Kalpana|Datta, Jharna|Smith, David Spencer|Bai, Shoumei|Jacob, Samson T
PMID: 16735507
Journal: Zhonghua Zhong Liu Za Zhi. 2006 Aug;28(8):564-7.
Title: [The effect of PKC-delta inhibitor Rottlerin on human colon cancer cell line SW1116 and its mechanism].
Author: Chen, Zhao-fei|Fang, Jing-yuan|Weng, Yu-rong|Sun, Dan-feng|Wang, Xia|Lu, Rong
PMID: 17236547
Journal: Cancer Lett. 2007 Feb 8;246(1-2):313-7.
Title: Trichostatin A down-regulate DNA methyltransferase 1 in Jurkat T cells.
Author: Januchowski, Radoslaw|Dabrowski, Mikolaj|Ofori, Harold|Jagodzinski, Pawel P
PMID: 16624484
Journal: Int J Colorectal Dis. 2007 Jun;22(6):661-6. Epub 2006 Nov 9.
Title: Expression of human DNA methyltransferase 1 in colorectal cancer tissues and their corresponding distant normal tissues.
Author: Zhu, Yi-Min|Huang, Qiong|Lin, Jie|Hu, Yu|Chen, Jian|Lai, Mao-De
PMID: 17093909
Journal: J Biol Chem. 2007 Apr 20;282(16):12249-59. Epub 2007 Feb 16.
Title: Inhibition of the extracellular signal-regulated kinase/mitogen-activated protein kinase pathway decreases DNA methylation in colon cancer cells.
Author: Lu, Rong|Wang, Xia|Chen, Zhao-Fei|Sun, Dan-Feng|Tian, Xiao-Qing|Fang, Jing-Yuan
PMID: 17307743
Journal: Nat Genet. 2007 Mar;39(3):391-6. Epub 2007 Feb 18.
Title: Complete inactivation of DNMT1 leads to mitotic catastrophe in human cancer cells.
Author: Chen, Taiping|Hevi, Sarah|Gay, Frederique|Tsujimoto, Naomi|He, Timothy|Zhang, Bailin|Ueda, Yoshihide|Li, En
PMID: 17322882
Journal: J Cell Physiol. 2007 Oct;213(1):65-9.
Title: Epigenetic inactivation of the metastasis suppressor RECK enhances invasion of human colon cancer cells.
Author: Cho, Chun-Yu|Wang, Jui-Ho|Chang, Hui-Chiu|Chang, Chong-Keng|Hung, Wen-Chun
PMID: 17443689
Journal: Mol Carcinog. 2007 Sep;46(9):766-72.
Title: Progressive up-regulation of genes encoding DNA methyltransferases in the colorectal adenoma-carcinoma sequence.
Author: Schmidt, Wolfgang M|Sedivy, Roland|Forstner, Birgit|Steger, Gunther G|Zochbauer-Muller, Sabine|Mader, Robert M
PMID: 17538945
Journal: Int J Cancer. 2007 Nov 15;121(10):2192-7.
Title: Association of the SUV39H1 histone methyltransferase with the DNA methyltransferase 1 at mRNA expression level in primary colorectal cancer.
Author: Kang, Mi Yeon|Lee, Bo Bin|Kim, Young-Ho|Chang, Dong Kyoung|Kyu Park, Seo|Chun, Ho-Kyung|Song, Sang Yong|Park, Joobae|Kim, Duk-Hwan
PMID: 17657744
Journal: Cancer Biol Ther. 2007 Aug;6(8):1284-8. Epub 2007 May 24.
Title: DNA methylation regulates MicroRNA expression.
Author: Han, Liangfeng|Witmer, P Dane|Casey, Emily|Valle, David|Sukumar, Saraswati
PMID: 17660710
Journal: Cancer Res. 2007 Dec 15;67(24):11481-6.
Title: Discovery of epigenetically silenced genes by methylated DNA immunoprecipitation in colon cancer cells.
Author: Jacinto, Filipe V|Ballestar, Esteban|Ropero, Santiago|Esteller, Manel
PMID: 18089774
Journal: FASEB J. 2008 Jun;22(6):1981-92.
Title: 15-Lipoxygenase-1 transcriptional silencing by DNA methyltransferase-1 independently of DNA methylation.
Author: Zuo, Xiangsheng|Shen, Lanlan|Issa, Jean-Pierre|Moy, Ofir|Morris, Jeffrey S|Lippman, Scott M|Shureiqi, Imad
PMID: 18198215
Journal: Oncogene. 2008 Jun 5;27(25):3615-23.
Title: p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage.
Author: Jiemjit, A|Fandy, T E|Carraway, H|Bailey, K A|Baylin, S|Herman, J G|Gore, S D
PMID: 18223691
Journal: Cancer. 2008 Apr 15;112(8):1699-707.
Title: Association of interindividual differences in p14ARF promoter methylation with single nucleotide polymorphism in primary colorectal cancer.
Author: Kang, Mi Yeon|Lee, Bo Bin|Ji, Yong Ick|Jung, Eun Hyun|Chun, Ho-Kyung|Song, Sang Yong|Park, Seong-Eun|Park, Joobae|Kim, Duk-Hwan
PMID: 18327804
Journal: Mol Cell Biol. 2008 May;28(10):3219-35.
Title: Histone deacetylase inhibitor depsipeptide activates silenced genes through decreasing both CpG and H3K9 methylation on the promoter.
Author: Wu, Li-Peng|Wang, Xi|Li, Lian|Zhao, Ying|Lu, Shaoli|Yu, Yu|Zhou, Wen|Liu, Xiangyu|Yang, Jing|Zheng, Zhixin|Zhang, Hui|Feng, Jingnan|Yang, Yang|Wang, Haiying|Zhu, Wei-Guo
PMID: 18332107
Journal: Br J Cancer. 2008 Jun 3;98(11):1810-9.
Title: SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response.
Author: Cheetham, S|Tang, M J|Mesak, F|Kennecke, H|Owen, D|Tai, I T
PMID: 18458674
Journal: Mol Cancer Res. 2008 Dec;6(12):1841-51.
Title: DNA methylation represses IFN-gamma-induced and signal transducer and activator of transcription 1-mediated IFN regulatory factor 8 activation in colon carcinoma cells.
Author: McGough, Jon M|Yang, Dafeng|Huang, Shuang|Georgi, David|Hewitt, Stephen M|Rocken, Christoph|Tanzer, Marc|Ebert, Matthias P A|Liu, Kebin
PMID: 19074829
Journal: Biochem J. 2009 Jan 1;417(1):379-89.
Title: Colon cancer cells maintain low levels of pyruvate to avoid cell death caused by inhibition of HDAC1/HDAC3.
Author: Thangaraju, Muthusamy|Carswell, Kristina N|Prasad, Puttur D|Ganapathy, Vadivel
PMID: 18789002
Journal: Br J Cancer. 2009 Feb 24;100(4):663-9.
Title: DLEC1 is a functional 3p22.3 tumour suppressor silenced by promoter CpG methylation in colon and gastric cancers.
Author: Ying, J|Poon, F F|Yu, J|Geng, H|Wong, A H Y|Qiu, G-H|Goh, H K|Rha, S Y|Tian, L|Chan, A T C|Sung, J J Y|Tao, Q
PMID: 19156137
Journal: Life Sci. 2009 Feb 27;84(9-10):311-20.
Title: Possible involvement of activation of P53/P21 and demethylation of RUNX 3 in the cytotoxicity against Lovo cells induced by 5-Aza-2'-deoxycytidine.
Author: Deng, Tao|Zhang, Yan
PMID: 19159630
Journal: Int J Colorectal Dis. 2009 Jun;24(6):629-39.
Title: Combined inhibition of Dnmt and mTOR signaling inhibits formation and growth of colorectal cancer.
Author: Zhang, Yan-Jie|Zhao, Shu-Liang|Tian, Xiao-Qing|Sun, Dan-Feng|Xiong, Hua|Dai, Qiang|Li, Xiao-Qiang|Fang, Jing-Yuan
PMID: 19229543
Journal: Int J Cancer. 2009 Oct 1;125(7):1626-39.
Title: Down-regulation of HLA Class I and NKG2D ligands through a concerted action of MAPK and DNA methyltransferases in colorectal cancer cells.
Author: Sers, Christine|Kuner, Ruprecht|Falk, Christine S|Lund, Per|Sueltmann, Holger|Braun, Monika|Buness, Andreas|Ruschhaupt, Markus|Conrad, Janine|Mang-Fatehi, Shila|Stelniec, Iwona|Krapfenbauer, Ulf|Poustka, Annemarie|Schafer, Reinhold
PMID: 19569244
Journal: Toxicol Lett. 2009 Dec 15;191(2-3):158-66.
Title: 5-Azacytidine prevents cisplatin induced nephrotoxicity and potentiates anticancer activity of cisplatin by involving inhibition of metallothionein, pAKT and DNMT1 expression in chemical induced cancer rats.
Author: Tikoo, Kulbhushan|Ali, Idrish Yunus|Gupta, Jeena|Gupta, Chanchal
PMID: 19723570
Journal: Cancer Res. 2009 Sep 15;69(18):7412-21.
Title: DNMT1 and DNMT3B modulate distinct polycomb-mediated histone modifications in colon cancer.
Author: Jin, Bilian|Yao, Bing|Li, Jian-Liang|Fields, C Robert|Delmas, Amber L|Liu, Chen|Robertson, Keith D
PMID: 19723660
Journal: Asian Pac J Cancer Prev. 2009;10(6):1183-8.
Title: Effects of amino acid substitution polymorphisms of two DNA methyltransferases on susceptibility to sporadic colorectal cancer.
Author: Khatami, Fatemeh|Noorinayer, Babak|Mohebi, Seyed Reza|Ghiasi, Somayeh|Mohebi, Reza|Hashemi, Mohhamad|Zali, Mohammad Reza
PMID: 20192566
Journal: Biochem Biophys Res Commun. 2010 Jan 1;391(1):449-54.
Title: TSA-induced DNMT1 down-regulation represses hTERT expression via recruiting CTCF into demethylated core promoter region of hTERT in HCT116.
Author: Choi, Jee-Hye|Min, Na Young|Park, Jina|Kim, Jin Hong|Park, Soo Hyun|Ko, Young Jong|Kang, Yoonsung|Moon, Young Joon|Rhee, Sangmyung|Ham, Seung Wook|Park, Ae Ja|Lee, Kwang-Ho
PMID: 19914212
Journal: J Huazhong Univ Sci Technolog Med Sci. 2010 Feb;30(1):69-74.
Title: Epigenetic regulation of the ERbeta gene on the estrogen signal transfection pathway in colon cancer cells.
Author: Zhai, Ronglin|Wang, Guobin|Cai, Kailin|Tao, Kaixiong|Xu, Fei|Zhang, Wanli|Wang, Zhiyong
PMID: 20155458
Journal: Int J Radiat Oncol Biol Phys. 2010 Apr;76(5):1512-9.
Title: Impact of genomic methylation on radiation sensitivity of colorectal carcinoma.
Author: Hofstetter, Barbara|Niemierko, Andrzej|Forrer, Christian|Benhattar, Jean|Albertini, Veronica|Pruschy, Martn|Bosman, Fred T|Catapano, Carlo V|Ciernik, I Frank
PMID: 20338477
Journal: Mol Cancer Res. 2010 Apr;8(4):471-81.
Title: Upregulation of DNA methyltransferase-mediated gene silencing, anchorage-independent growth, and migration of colon cancer cells by interleukin-6.
Author: Foran, Eilis|Garrity-Park, Megan M|Mureau, Coralie|Newell, John|Smyrk, Thomas C|Limburg, Paul J|Egan, Laurence J
PMID: 20354000
Journal: PLoS One. 2010 Apr 29;5(4):e10338.
Title: HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors.
Author: Ghoshal, Kalpana|Motiwala, Tasneem|Claus, Rainer|Yan, Pearlly|Kutay, Huban|Datta, Jharna|Majumder, Sarmila|Bai, Shoumei|Majumder, Arnab|Huang, Tim|Plass, Christoph|Jacob, Samson T
PMID: 20454457
Journal: Epigenetics. 2010 Aug 16;5(6):547-56. Epub 2010 Aug 16.
Title: Ischemia dysregulates DNA methyltransferases and p16INK4a methylation in human colorectal cancer cells.
Author: Skowronski, Karolina|Dubey, Sonam|Rodenhiser, David|Coomber, Brenda
PMID: 20543577
Journal: Oncogene. 2010 Oct 28;29(43):5775-84.
Title: Demethylation of a LINE-1 antisense promoter in the cMet locus impairs Met signalling through induction of illegitimate transcription.
Author: Weber, B|Kimhi, S|Howard, G|Eden, A|Lyko, F
PMID: 20562909
Journal: Digestion. 2010;82(3):179-86.
Title: Increased expression of DNA methyltransferase-1 in non-neoplastic epithelium helps predict colorectal neoplasia risk in ulcerative colitis.
Author: Fujii, Shigehiko|Katake, Yoshiki|Tanaka, Hiroyuki
PMID: 20588031
Journal: Sci Signal. 2010 Nov 2;3(146):ra80.
Title: DNMT1 stability is regulated by proteins coordinating deubiquitination and acetylation-driven ubiquitination.
Author: Du, Zhanwen|Song, Jing|Wang, Yong|Zhao, Yiqing|Guda, Kishore|Yang, Shuming|Kao, Hung-Ying|Xu, Yan|Willis, Joseph|Markowitz, Sanford D|Sedwick, David|Ewing, Robert M|Wang, Zhenghe
PMID: 21045206
Journal: Sichuan Da Xue Xue Bao Yi Xue Ban. 2010 Nov;41(6):975-9.
Title: [Effect and mechanism of DNMT inhibitor on the reversal of multidrug resistance in human colon cancer cell line sw620/L-OHP].
Author: Deng, Qian|Li, Zhi-ping|Huang, Chun-mei|Liu, Zhen|Zhong, Ren-ming|Li, Ai-jun|Bi, Feng|Tang, Qiu-lin
PMID: 21265097
Journal: Int J Cancer. 2011 Feb 1;128(3):551-61.
Title: DNMT3a plays a role in switches between doxorubicin-induced senescence and apoptosis of colorectal cancer cells.
Author: Zhang, Yu|Gao, Yanyan|Zhang, Guoping|Huang, Shuyan|Dong, Zhixiong|Kong, Chenfei|Su, Dongmei|Du, Juan|Zhu, Shan|Liang, Qian|Zhang, Jianchao|Lu, Jun|Huang, Baiqu
PMID: 20473858
Journal: Proc Nutr Soc. 2011 Feb;70(1):47-56.
Title: Epigenetic modifications and human pathologies: cancer and CVD.
Author: Duthie, Susan J
PMID: 21067630
Journal: Clin Cancer Res. 2011 Feb 1;17(3):598-610.
Title: Modulation of genetic and epigenetic biomarkers of colorectal cancer in humans by black raspberries: a phase I pilot study.
Author: Wang, Li-Shu|Arnold, Mark|Huang, Yi-Wen|Sardo, Christine|Seguin, Claire|Martin, Edward|Huang, Tim H-M|Riedl, Ken|Schwartz, Steven|Frankel, Wendy|Pearl, Dennis|Xu, Yiqing|Winston, John 3rd|Yang, Guang-Yu|Stoner, Gary
PMID: 21123457
Journal: PLoS One. 2011 Mar 7;6(3):e17388.
Title: Azacytidine and decitabine induce gene-specific and non-random DNA demethylation in human cancer cell lines.
Author: Hagemann, Sabine|Heil, Oliver|Lyko, Frank|Brueckner, Bodo
PMID: 21408221
Journal: PLoS One. 2011 Apr 19;6(4):e18844.
Title: Relationship between gene body DNA methylation and intragenic H3K9me3 and H3K36me3 chromatin marks.
Author: Hahn, Maria A|Wu, Xiwei|Li, Arthur X|Hahn, Torsten|Pfeifer, Gerd P
PMID: 21526191
Journal: Int J Mol Epidemiol Genet. 2011 Jan 1;2(1):1-8. Epub 2010 Nov 5.
Title: Candidate pathway polymorphisms in one-carbon metabolism and risk of rectal tumor mutations.
Author: Curtin, Karen|Ulrich, Cornelia M|Samowitz, Wade S|Wolff, Roger K|Duggan, David J|Makar, Karen W|Caan, Bette J|Slattery, Martha L
PMID: 21537397
Journal: Gut. 2011 Nov;60(11):1544-53.
Title: Statins augment the chemosensitivity of colorectal cancer cells inducing epigenetic reprogramming and reducing colorectal cancer cell 'stemness' via the bone morphogenetic protein pathway.
Author: Kodach, Liudmila L|Jacobs, Rutger J|Voorneveld, Philip W|Wildenberg, Manon E|Verspaget, Henricus W|van Wezel, Tom|Morreau, Hans|Hommes, Daniel W|Peppelenbosch, Maikel P|van den Brink, Gijs R|Hardwick, James C H
PMID: 21551187
Journal: Carcinogenesis. 2011 Jul;32(7):1033-42.
Title: MicroRNA-342 inhibits colorectal cancer cell proliferation and invasion by directly targeting DNA methyltransferase 1.
Author: Wang, Hui|Wu, Jiangxue|Meng, Xiangqi|Ying, Xiaofang|Zuo, Yufang|Liu, Ranyi|Pan, Zhizhong|Kang, Tiebang|Huang, Wenlin
PMID: 21565830
Journal: Hum Mol Genet. 2011 Aug 15;20(16):3241-55.
Title: DNMT1 deficiency triggers mismatch repair defects in human cells through depletion of repair protein levels in a process involving the DNA damage response.
Author: Loughery, Jayne E P|Dunne, Philip D|O'Neill, Karla M|Meehan, Richard R|McDaid, Jennifer R|Walsh, Colum P
PMID: 21636528
Journal: Nucleic Acids Res. 2011 Oct;39(19):e127.
Title: Targeted bisulfite sequencing by solution hybrid selection and massively parallel sequencing.
Author: Lee, Eun-Joon|Pei, Lirong|Srivastava, Gyan|Joshi, Trupti|Kushwaha, Garima|Choi, Jeong-Hyeon|Robertson, Keith D|Wang, Xinguo|Colbourne, John K|Zhang, Lu|Schroth, Gary P|Xu, Dong|Zhang, Kun|Shi, Huidong
PMID: 21785137
Journal: J Antibiot (Tokyo). 2011 Sep;64(9):635-44.
Title: Molecular basis for the actions of Hsp90 inhibitors and cancer therapy.
Author: Yamaki, Hiroshi|Nakajima, Motowo|Shimotohno, Kumiko W|Tanaka, Nobuo
PMID: 21811259
Journal: J Med Chem. 2011 Nov 10;54(21):7663-77.
Title: Synthesis and biochemical evaluation of delta(2)-isoxazoline derivatives as DNA methyltransferase 1 inhibitors.
Author: Castellano, Sabrina|Kuck, Dirk|Viviano, Monica|Yoo, Jakyung|Lopez-Vallejo, Fabian|Conti, Paola|Tamborini, Lucia|Pinto, Andrea|Medina-Franco, Jose L|Sbardella, Gianluca
PMID: 21958292
Journal: Tumour Biol. 2012 Apr;33(2):403-12.
Title: Epigenetic changes induced by oxidative stress in colorectal cancer cells: methylation of tumor suppressor RUNX3.
Author: Kang, Kyoung Ah|Zhang, Rui|Kim, Gi Young|Bae, Suk Chul|Hyun, Jin Won
PMID: 22274925
Journal: Nucleic Acids Res. 2012 May;40(10):4334-46.
Title: DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes.
Author: Clements, Eriko G|Mohammad, Helai P|Leadem, Benjamin R|Easwaran, Hariharan|Cai, Yi|Van Neste, Leander|Baylin, Stephen B
PMID: 22278882
Journal: Cancer Biol Ther. 2012 May;13(7):542-52.
Title: Boswellic acid induces epigenetic alterations by modulating DNA methylation in colorectal cancer cells.
Author: Shen, Yan|Takahashi, Masanobu|Byun, Hyang-Min|Link, Alexander|Sharma, Nupur|Balaguer, Francesc|Leung, Hon-Chiu E|Boland, C Richard|Goel, Ajay
PMID: 22415137
Journal: Epigenetics. 2012 Jun 1;7(6):585-93.
Title: Human cytomegalovirus infection is sensitive to the host cell DNA methylation state and alters global DNA methylation capacity.
Author: Esteki-Zadeh, Atosa|Karimi, Mohsen|Straat, Klas|Ammerpohl, Ole|Zeitelhofer, Manuel|Jagodic, Maja|Mehrab-Mohseni, Marjan|Sjoholm, Louise|Rahbar, Afsar|Soderberg-Naucler, Cecilia|Ekstrom, Tomas J
PMID: 22595877
Journal: Carcinogenesis. 2012 Oct;33(10):1889-96.
Title: IL-6-induced DNMT1 activity mediates SOCS3 promoter hypermethylation in ulcerative colitis-related colorectal cancer.
Author: Li, Yi|Deuring, Jasper|Peppelenbosch, Maikel P|Kuipers, Ernst J|de Haar, Colin|van der Woude, C Janneke
PMID: 22739025
Journal: Chemotherapy. 2012;58(6):445-53.
Title: Chemotherapy and radiotherapy downregulate the activity and expression of DNA methyltransferase and enhance Bcl-2/E1B-19-kDa interacting protein-3-induced apoptosis in human colorectal cancer cells.
Author: Deng, Qian|Huang, Chun-mei|Chen, Ni|Li, Li|Wang, Xiao-dong|Zhang, Wen|Bi, Feng|Tang, Qiu-lin|Li, Zhi-ping|Wang, Wei
PMID: 23364257
Journal: Mol Nutr Food Res. 2013 Apr;57(4):721-34.
Title: Gene-diet-interactions in folate-mediated one-carbon metabolism modify colon cancer risk.
Author: Liu, Amy Y|Scherer, Dominique|Poole, Elizabeth|Potter, John D|Curtin, Karen|Makar, Karen|Slattery, Martha L|Caan, Bette J|Ulrich, Cornelia M
PMID: 22961839
Journal: Exp Mol Pathol. 2013 Apr;94(2):322-9.
Title: DNA methyltransferase 1 is essential for initiation of the colon cancers.
Author: Morita, Rena|Hirohashi, Yoshihiko|Suzuki, Hiromu|Takahashi, Akari|Tamura, Yasuaki|Kanaseki, Takayuki|Asanuma, Hiroko|Inoda, Satoko|Kondo, Toru|Hashino, Satoshi|Hasegawa, Tadashi|Tokino, Takashi|Toyota, Minoru|Asaka, Masahiro|Torigoe, Toshihiko|Sato, Noriy
PMID: 23064049
Journal: Biochem J. 2013 Jan 15;449(2):459-68.
Title: Loss of LSD1 (lysine-specific demethylase 1) suppresses growth and alters gene expression of human colon cancer cells in a p53- and DNMT1(DNA methyltransferase 1)-independent manner.
Author: Jin, Lihua|Hanigan, Christin L|Wu, Yu|Wang, Wei|Park, Ben Ho|Woster, Patrick M|Casero, Robert A
PMID: 23072722
Journal: Nutr Cancer. 2013;65(1):118-25.
Title: Black raspberry-derived anthocyanins demethylate tumor suppressor genes through the inhibition of DNMT1 and DNMT3B in colon cancer cells.
Author: Wang, Li-Shu|Kuo, Chieh-Ti|Cho, Seung-Ju|Seguin, Claire|Siddiqui, Jibran|Stoner, Kristen|Weng, Yu-I|Huang, Tim H-M|Tichelaar, Jay|Yearsley, Martha|Stoner, Gary D|Huang, Yi-Wen
PMID: 23368921
Journal: Oncol Lett. 2013 Apr;5(4):1273-1277.
Title: Epigenetic effects of the natural flavonolignan silibinin on colon adenocarcinoma cells and their derived metastatic cells.
Author: Kauntz, Henriette|Bousserouel, Souad|Gosse, Francine|Raul, Francis
PMID: 23599778
Journal: Gene. 2013 Jul 25;524(2):214-9.
Title: Oxidative stress causes epigenetic alteration of CDX1 expression in colorectal cancer cells.
Author: Zhang, Rui|Kang, Kyoung Ah|Kim, Ki Cheon|Na, Soo-Young|Chang, Weon Young|Kim, Gi Young|Kim, Hye Sun|Hyun, Jin Won
PMID: 23618814
Journal: Bioorg Med Chem. 2013 Jun 1;21(11):3147-53.
Title: Structure-activity relationships for 4-anilinoquinoline derivatives as inhibitors of the DNA methyltransferase enzyme DNMT1.
Author: Gamage, Swarna A|Brooke, Darby G|Redkar, Sanjeev|Datta, Jharna|Jacob, Samson T|Denny, William A
PMID: 23639684
Journal: PLoS One. 2013 May 23;8(5):e64362.
Title: Combination of selenium and green tea improves the efficacy of chemoprevention in a rat colorectal cancer model by modulating genetic and epigenetic biomarkers.
Author: Hu, Ying|McIntosh, Graeme H|Le Leu, Richard K|Nyskohus, Laura S|Woodman, Richard J|Young, Graeme P
PMID: 23717604
Journal: Sci Rep. 2013 Nov 14;3:3219.
Title: Zebularine inhibits tumorigenesis and stemness of colorectal cancer via p53-dependent endoplasmic reticulum stress.
Author: Yang, Pei-Ming|Lin, Yi-Ting|Shun, Chia-Tung|Lin, Shan-Hu|Wei, Tzu-Tang|Chuang, Shu-Hui|Wu, Ming-Shiang|Chen, Ching-Chow
PMID: 24225777
Journal: Asian Pac J Cancer Prev. 2013;14(10):5609-14.
Title: Genes and SNPs associated with non-hereditary and hereditary colorectal cancer.
Author: Nassiri, Mohammadreza|Kooshyar, Mohammad Mahdi|Roudbar, Zahra|Mahdavi, Morteza|Doosti, Mohammad
PMID: 24289550
Journal: Anticancer Res. 2013 Dec;33(12):5325-33.
Title: Green tea polyphenol epigallocatechin 3-gallate, contributes to the degradation of DNMT3A and HDAC3 in HCT 116 human colon cancer cells.
Author: Moseley, Vondina R|Morris, Jay|Knackstedt, Rebecca W|Wargovich, Michael J
PMID: 24324066
Journal: Oncogene. 2014 Apr 24;33(17):2157-68.
Title: The NuRD complex cooperates with DNMTs to maintain silencing of key colorectal tumor suppressor genes.
Author: Cai, Y|Geutjes, E-J|de Lint, K|Roepman, P|Bruurs, L|Yu, L-R|Wang, W|van Blijswijk, J|Mohammad, H|de Rink, I|Bernards, R|Baylin, S B
PMID: 23708667
Journal: Biol Pharm Bull. 2014;37(1):67-73. Epub 2013 Oct 29.
Title: Different effects of epigenetic modifiers on the cytotoxicity induced by 5-fluorouracil, irinotecan or oxaliplatin in colon cancer cells.
Author: Ikehata, Mika|Ogawa, Mao|Yamada, Yasuki|Tanaka, Shota|Ueda, Kumiko|Iwakawa, Seigo
PMID: 24172061
Journal: Carcinogenesis. 2014 Jun;35(6):1330-40.
Title: IL-23 selectively promotes the metastasis of colorectal carcinoma cells with impaired Socs3 expression via the STAT5 pathway.
Author: Zhang, Le|Li, Jun|Li, Li|Zhang, Jie|Wang, Xiaodong|Yang, Chuanhua|Li, Yanyan|Lan, Feng|Lin, Ping
PMID: 24464786
Journal: Exp Cell Res. 2014 May 15;324(1):40-53.
Title: Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate.
Author: Saldanha, Sabita N|Kala, Rishabh|Tollefsbol, Trygve O
PMID: 24518414
Journal: PLoS One. 2014 Mar 27;9(3):e92305.
Title: DNA methyltransferase inhibitors improve the effect of chemotherapeutic agents in SW48 and HT-29 colorectal cancer cells.
Author: Flis, Sylwia|Gnyszka, Agnieszka|Flis, Krzysztof
PMID: 24676085
Journal: Front Oncol. 2014 May 1;4:80.
Title: DNA methyltransferases: a novel target for prevention and therapy.
Author: Subramaniam, Dharmalingam|Thombre, Ravi|Dhar, Animesh|Anant, Shrikant
PMID: 24822169
Journal: J Biomed Sci. 2014 Aug 9;21:73.
Title: Promoter methylation analysis of WNT/beta-catenin pathway regulators and its association with expression of DNMT1 enzyme in colorectal cancer.
Author: Samaei, Nader Mansour|Yazdani, Yaghoub|Alizadeh-Navaei, Reza|Azadeh, Hossein|Farazmandfar, Touraj
PMID: 25107489
Journal: Nutr Cancer. 2014;66(7):1220-7.
Title: Luteolin induces apoptosis in BE colorectal cancer cells by downregulating calpain, UHRF1, and DNMT1 expressions.
Author: Krifa, Mounira|Leloup, Ludovic|Ghedira, Kamel|Mousli, Marc|Chekir-Ghedira, Leila
PMID: 25207720
Journal: Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):14985-9.
Title: Label-free electrochemical detection of human methyltransferase from tumors.
Author: Furst, Ariel L|Muren, Natalie B|Hill, Michael G|Barton, Jacqueline K
PMID: 25288757
Journal: Cell Oncol (Dordr). 2014 Dec;37(6):455-61.
Title: Somatic mutations of amino acid metabolism-related genes in gastric and colorectal cancers and their regional heterogeneity--a short report.
Author: Oh, Hye Rim|An, Chang Hyeok|Yoo, Nam Jin|Lee, Sug Hyung
PMID: 25450519
Journal: Mol Oncol. 2015 Feb;9(2):450-62.
Title: PHF21B as a candidate tumor suppressor gene in head and neck squamous cell carcinomas.
Author: Bertonha, Fernanda Bernardi|Barros Filho, Mateus de Camargo|Kuasne, Hellen|Dos Reis, Patricia Pintor|da Costa Prando, Erika|Munoz, Juan Jose Augusto Moyano|Roffe, Martin|Hajj, Glaucia Noeli Maroso|Kowalski, Luiz Paulo|Rainho, Claudia Aparecida|Rogatto, Si
PMID: 25454821
Journal: Cancer Lett. 2015 Apr 10;359(2):198-205.
Title: DNMT1 and EZH2 mediated methylation silences the microRNA-200b/a/429 gene and promotes tumor progression.
Author: Ning, Xianghong|Shi, Zhendong|Liu, Xi|Zhang, Anling|Han, Lei|Jiang, Kui|Kang, Chunsheng|Zhang, Qingyu
PMID: 25595591
Journal: Epigenetics. 2015;10(4):303-18.
Title: Mycoplasma CG- and GATC-specific DNA methyltransferases selectively and efficiently methylate the host genome and alter the epigenetic landscape in human cells.
Author: Chernov, Andrei V|Reyes, Leticia|Xu, Zhenkang|Gonzalez, Beatriz|Golovko, Georgiy|Peterson, Scott|Perucho, Manuel|Fofanov, Yuriy|Strongin, Alex Y
PMID: 25695131
Journal: Mol Cancer Res. 2015 Jun;13(6):969-81.
Title: A Protein Interaction between beta-Catenin and Dnmt1 Regulates Wnt Signaling and DNA Methylation in Colorectal Cancer Cells.
Author: Song, Jing|Du, Zhanwen|Ravasz, Mate|Dong, Bohan|Wang, Zhenghe|Ewing, Rob M
PMID: 25753001
Journal: J Nutr Biochem. 2015 Aug;26(8):818-26.
Title: The effects of folic acid on global DNA methylation and colonosphere formation in colon cancer cell lines.
Author: Farias, Nathan|Ho, Nelson|Butler, Stacey|Delaney, Leanne|Morrison, Jodi|Shahrzad, Siranoush|Coomber, Brenda L
PMID: 25804133
Journal: BMC Genomics. 2015 Feb 6;16:56.
Title: Identification of radiation-induced aberrant hypomethylation in colon cancer.
Author: Bae, Jin-Han|Kim, Joong-Gook|Heo, Kyu|Yang, Kwangmo|Kim, Tae-Oh|Yi, Joo Mi
PMID: 25887185
Journal: J Inorg Biochem. 2015 Sep;150:18-27.
Title: Synthesis, chemical characterization, computational studies and biological activity of new DNA methyltransferases (DNMTs) specific inhibitor. Epigenetic regulation as a new and potential approach to cancer therapy.
Author: Pellerito, C|Morana, O|Ferrante, F|Calvaruso, G|Notaro, A|Sabella, S|Fiore, T
PMID: 26072325
Journal: Cancer. 2015 Oct 15;121(20):3684-91.
Title: Folate-mediated one-carbon metabolism genes and interactions with nutritional factors on colorectal cancer risk: Women's Health Initiative Observational Study.
Author: Cheng, Ting-Yuan David|Makar, Karen W|Neuhouser, Marian L|Miller, Joshua W|Song, Xiaoling|Brown, Elissa C|Beresford, Shirley A A|Zheng, Yingye|Poole, Elizabeth M|Galbraith, Rachel L|Duggan, David J|Habermann, Nina|Bailey, Lynn B|Maneval, David R|Caudill,
PMID: 26108676
Journal: Chem Biol. 2015 Jul 23;22(7):938-45.
Title: DNA Electrochemistry Shows DNMT1 Methyltransferase Hyperactivity in Colorectal Tumors.
Author: Furst, Ariel L|Barton, Jacqueline K
PMID: 26120002
Journal: Biol Pharm Bull. 2015;38(9):1272-9.
Title: Effects of Decitabine on Invasion and Exosomal Expression of miR-200c and miR-141 in Oxaliplatin-Resistant Colorectal Cancer Cells.
Author: Tanaka, Shota|Hosokawa, Mika|Ueda, Kumiko|Iwakawa, Seigo
PMID: 26179333
Journal: Genes Chromosomes Cancer. 2015 Dec;54(12):776-87.
Title: Methyltransferase expression and tumor suppressor gene methylation in sporadic and familial colorectal cancer.
Author: Joensuu, Emmi I|Nieminen, Taina T|Lotsari, Johanna E|Pavicic, Walter|Abdel-Rahman, Wael M|Peltomaki, Paivi
PMID: 26305882
Journal: Hum Mol Genet. 2015 Nov 1;24(21):6240-53.
Title: DNMT1-associated long non-coding RNAs regulate global gene expression and DNA methylation in colon cancer.
Author: Merry, Callie R|Forrest, Megan E|Sabers, Jessica N|Beard, Lydia|Gao, Xing-Huang|Hatzoglou, Maria|Jackson, Mark W|Wang, Zhenghe|Markowitz, Sanford D|Khalil, Ahmad M
PMID: 26307088
Journal: Cell Biochem Funct. 2015 Oct;33(7):427-33.
Title: Association of DNA methyltransferases expression with global and gene-specific DNA methylation in colorectal cancer cells.
Author: Sarabi, Mostafa Moradi|Naghibalhossaini, Fakhraddin
PMID: 26416384
Journal: J Nutrigenet Nutrigenomics. 2015;8(3):114-27.
Title: Phytochemical Indicaxanthin Inhibits Colon Cancer Cell Growth and Affects the DNA Methylation Status by Influencing Epigenetically Modifying Enzyme Expression and Activity.
Author: Naselli, Flores|Belshaw, Nigel Junior|Gentile, Carla|Tutone, Marco|Tesoriere, Luisa|Livrea, Maria Antonietta|Caradonna, Fabio
PMID: 26439130
Journal: Int J Oncol. 2015 Dec;47(6):2264-75.
Title: Radiation-induced modulation of immunogenic genes in tumor cells is regulated by both histone deacetylases and DNA methyltransferases.
Author: Cacan, Ercan|Greer, Susanna F|Garnett-Benson, Charlie
PMID: 26458736
Journal: Oncotarget. 2015 Nov 10;6(35):38139-50.
Title: miR-124 and miR-506 inhibit colorectal cancer progression by targeting DNMT3B and DNMT1.
Author: Chen, Zhiheng|Liu, Shaojun|Tian, Li|Wu, Minghao|Ai, Feiyan|Tang, Wuliang|Zhao, Lian|Ding, Juan|Zhang, Liyang|Tang, Anliu
PMID: 26497367
Journal: Oncol Lett. 2015 Aug;10(2):761-767.
Title: Acquired resistance to decitabine and cross-resistance to gemcitabine during the long-term treatment of human HCT116 colorectal cancer cells with decitabine.
Author: Hosokawa, Mika|Saito, Mai|Nakano, Aiko|Iwashita, Sakura|Ishizaka, Ayano|Ueda, Kumiko|Iwakawa, Seigo
PMID: 26622566
Journal: J Mol Cell Biol. 2016 Jun;8(3):244-54.
Title: Mismatch repair proteins recruit DNA methyltransferase 1 to sites of oxidative DNA damage.
Author: Ding, Ning|Bonham, Emily M|Hannon, Brooke E|Amick, Thomas R|Baylin, Stephen B|O'Hagan, Heather M
PMID: 26186941
Journal: Cancer Prev Res (Phila). 2016 Jul;9(7):534-46.
Title: DNA Hypomethylation Contributes to Genomic Instability and Intestinal Cancer Initiation.
Author: Sheaffer, Karyn L|Elliott, Ellen N|Kaestner, Klaus H
PMID: 26883721
Journal: Sci Rep. 2016 May 4;6:25311.
Title: Inhibition of DNA Methylation Suppresses Intestinal Tumor Organoids by Inducing an Anti-Viral Response.
Author: Saito, Yoshimasa|Nakaoka, Toshiaki|Sakai, Kasumi|Muramatsu, Toshihide|Toshimitsu, Kohta|Kimura, Masaki|Kanai, Takanori|Sato, Toshiro|Saito, Hidetsugu
PMID: 27143627
Journal: Asian Pac J Cancer Prev. 2016;17(6):3015-20.
Title: DNMT3B -149 C>T and -579 G>T Polymorphisms and Risk of Gastric and Colorectal Cancer: a Meta-analysis.
Author: Khoram-Abadi, Khadijeh Mirzaee|Forat-Yazdi, Mohammad|Kheirandish, Shahnaz|Saeidi, Nasim|Zarezade, Zeinab|Mehrabi, Nahid|Neamatzadeh, Hossein
PMID: 27356727
Journal: Oncol Rep. 2016 Nov;36(5):2705-2714.
Title: Expression of DNA methyltransferases and target microRNAs in human tissue samples related to sporadic colorectal cancer.
Author: Huang, Chao|Liu, Hong|Gong, Xiu-Li|Wu, Liyun|Wen, Bin
PMID: 27666771
Journal: Life Sci. 2016 Dec 15;167:67-77.
Title: Arsenic trioxide induces cell cycle arrest and alters DNA methylation patterns of cell cycle regulatory genes in colorectal cancer cells.
Author: Eyvani, Haniyeh|Moghaddaskho, Farima|Kabuli, Majid|Zekri, Ali|Momeny, Majid|Tavakkoly-Bazzaz, Javad|Alimoghaddam, Kamran|Ghavamzadeh, Ardeshir|Ghaffari, Seyed H
PMID: 27769816
Journal: Mol Carcinog. 2017 Feb;56(2):712-721.
Title: Reelin-Dab1 signaling system in human colorectal cancer.
Author: Serrano-Morales, Jose Manuel|Vazquez-Carretero, Maria Dolores|Peral, Maria Jose|Ilundain, Anunciacion Ana|Garcia-Miranda, Pablo
PMID: 27434856
Journal: Avicenna J Med Biotechnol. 2017 Jan-Mar;9(1):13-18.
Title: Induction of Epigenetic Alteration by CPUK02, An Ent- kaurenoid Derivative of Stevioside.
Author: Mokarram, Pooneh|Mohammadi, Zeinab|Khazayel, Saeid|Dayong, Zhang
PMID: 28090275
Journal: Oncol Rep. 2017 Mar;37(3):1637-1645.
Title: Effect of evodiamine and berberine on the interaction between DNMTs and target microRNAs during malignant transformation of the colon by TGF-beta1.
Author: Huang, Chao|Liu, Hong|Gong, Xiu-Li|Wu, Li-Yun|Wen, Bin
PMID: 28098901
Journal: BMC Cell Biol. 2017 Feb 27;18(1):14.
Title: Hinokitiol induces DNA demethylation via DNMT1 and UHRF1 inhibition in colon cancer cells.
Author: Seo, Jung Seon|Choi, Young Ha|Moon, Ji Wook|Kim, Hyeon Soo|Park, Sun-Hwa
PMID: 28241740
Journal: Epigenetics. 2017 Jun 3;12(6):465-475.
Title: Decoupling of DNA methylation and activity of intergenic LINE-1 promoters in colorectal cancer.
Author: Vafadar-Isfahani, Natasha|Parr, Christina|McMillan, Lara E|Sanner, Juliane|Yeo, Zhao|Saddington, Stephen|Peacock, Oliver|Cruickshanks, Hazel A|Meehan, Richard R|Lund, Jonathan N|Tufarelli, Cristina
PMID: 28300471
Journal: J Med Chem. 2017 Jun 8;60(11):4665-4679.
Title: Rational Design of Bisubstrate-Type Analogues as Inhibitors of DNA Methyltransferases in Cancer Cells.
Author: Halby, Ludovic|Menon, Yoann|Rilova, Elodie|Pechalrieu, Dany|Masson, Veronique|Faux, Celine|Bouhlel, Mohamed Amine|David-Cordonnier, Marie-Helene|Novosad, Natacha|Aussagues, Yannick|Samson, Arnaud|Lacroix, Laurent|Ausseil, Frederic|Fleury, Laurence|Guianva
PMID: 28463515
Journal: Cancer Lett. 2017 Aug 28;402:110-116.
Title: Epigenetic effects of inhibition of heat shock protein 90 (HSP90) in human pancreatic and colon cancer.
Author: Nagaraju, Ganji Purnachandra|Wu, Christina|Merchant, Neha|Chen, Zhengjia|Lesinski, Gregory B|El-Rayes, Bassel F
PMID: 28583846
Journal: J Cancer. 2017 Apr 9;8(7):1187-1196.
Title: Chemoresistance of colorectal cancer to 5-fluorouracil is associated with silencing of the BNIP3 gene through aberrant methylation.
Author: He, Jianming|Pei, Li|Jiang, Heng|Yang, Weiwen|Chen, Jianfang|Liang, Houjie
PMID: 28607593
Journal: Genes Chromosomes Cancer. 2017 Nov;56(11):769-787.
Title: The co-regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer.
Author: Slattery, Martha L|Herrick, Jennifer S|Mullany, Lila E|Samowitz, Wade S|Sevens, John R|Sakoda, Lori|Wolff, Roger K
PMID: 28675510
Journal: Med Oncol. 2017 Aug;34(8):147.
Title: Clinical and prognosis value of the CIMP status combined with MLH1 or p16 (INK4a) methylation in colorectal cancer.
Author: Saadallah-Kallel, Amana|Abdelmaksoud-Dammak, Rania|Triki, Mouna|Charfi, Slim|Khabir, Abdelmajid|Sallemi-Boudawara, Tahia|Mokdad-Gargouri, Raja
PMID: 28730335
Journal: Pharmacol Res. 2018 Mar;129:318-328.
Title: DACT2 Epigenetic Stimulator Exerts Dual Efficacy for Colorectal Cancer Prevention and Treatment.
Author: Lu, Linlin|Wang, Ying|Ou, Rilan|Feng, Qian|Ji, Liyan|Zheng, Hongming|Guo, Yue|Qi, Xiaoxiao|Kong, Ah-Ng Tony|Liu, Zhongqiu
PMID: 29199082
Journal: Biomed Pharmacother. 2018 May;101:94-99.
Title: The impact of polyunsaturated fatty acids on DNA methylation and expression of DNMTs in human colorectal cancer cells.
Author: Sarabi, Mostafa Moradi|Naghibalhossaini, Fakhraddin
PMID: 29477476
Journal: Oncogene. 2018 Jun;37(25):3440-3455.
Title: Mutant KRAS promotes liver metastasis of colorectal cancer, in part, by upregulating the MEK-Sp1-DNMT1-miR-137-YB-1-IGF-IR signaling pathway.
Author: Chu, Po-Chen|Lin, Peng-Chan|Wu, Hsing-Yu|Lin, Kuen-Tyng|Wu, Christina|Bekaii-Saab, Tanios|Lin, Yih-Jyh|Lee, Chung-Ta|Lee, Jeng-Chang|Chen, Ching-Shih
PMID: 29559746
Journal: Cell Signal. 2018 Jul;47:79-87.
Title: Inhibition of DNMT suppresses the stemness of colorectal cancer cells through down-regulating Wnt signaling pathway.
Author: Li, Shanxin|Han, Zhipeng|Zhao, Naping|Zhu, Bing|Zhang, Qianwen|Yang, Xue|Sheng, Dandan|Hou, Jing|Guo, Shiwei|Wei, Lixin|Zhang, Li
PMID: 29601907
Journal: Exp Cell Res. 2018 Jun 15;367(2):216-221.
Title: NUSAP1 gene silencing inhibits cell proliferation, migration and invasion through inhibiting DNMT1 gene expression in human colorectal cancer.
Author: Han, Guoda|Wei, Zhijiang|Cui, Haibin|Zhang, Wei|Wei, Xiaonan|Lu, Zhiliang|Bai, Xiyong
PMID: 29608915
Journal: Oxid Med Cell Longev. 2018 Mar 22;2018:3734250.
Title: Counteraction of Oxidative Stress by Vitamin E Affects Epigenetic Regulation by Increasing Global Methylation and Gene Expression of MLH1 and DNMT1 Dose Dependently in Caco-2 Cells.
Author: Zappe, Katja|Pointner, Angelika|Switzeny, Olivier J|Magnet, Ulrich|Tomeva, Elena|Heller, Jutta|Mare, George|Wagner, Karl-Heinz|Knasmueller, Siegfried|Haslberger, Alexander G
PMID: 29854080
Journal: Oncotarget. 2018 May 25;9(40):26243-26258.
Title: Targeting the SET and RING-associated (SRA) domain of ubiquitin-like, PHD and ring finger-containing 1 (UHRF1) for anti-cancer drug development.
Author: Patnaik, Debasis|Esteve, Pierre-Olivier|Pradhan, Sriharsa
PMID: 29899856
Journal: Oncol Rep. 2018 Aug;40(2):1165-1173.
Title: Wnt signaling pathway upregulates DNMT1 to trigger NHERF1 promoter hypermethylation in colon cancer.
Author: Guo, Yongli|Wang, Meng|Jia, Xuefeng|Zhu, Hua|Zhi, Yaqin|Yuan, Leilei
PMID: 29901158
Journal: Int J Mol Sci. 2018 Jun 29;19(7). pii: ijms19071909.
Title: The Curcumin Analog CH-5 Exerts Anticancer Effects in Human Osteosarcoma Cells via Modulation of Transcription Factors p53/Sp1.
Author: Lima, Felipe Teixeira|Seba, Viviane|Silva, Gabriel|Torrezan, Guilherme Silva|Polaquini, Carlos Roberto|Pinhanelli, Vitor Caressato|Baek, Seung J|Fachin, Ana Lucia|Regasini, Luis Octavio|Marins, Mozart
PMID: 29966255
Journal: ACS Sens. 2018 Sep 28;3(9):1765-1772.
Title: Curvature-Mediated Surface Accessibility Enables Ultrasensitive Electrochemical Human Methyltransferase Analysis.
Author: Wang, Guangli|Das, Jagotamoy|Ahmed, Sharif|Nemr, Carine R|Zhang, Libing|Poudineh, Mahla|Sargent, Edward H|Kelley, Shana O
PMID: 30080023