Primary Site >> Pancreatic Cancer

Gene >> DNER

Journal: Mol Cancer Ther. 2014 Jul;13(7):1907-17.
Title: BET bromodomain inhibitors block growth of pancreatic cancer cells in three-dimensional collagen.
Author: Sahai, Vaibhav|Kumar, Krishan|Knab, Lawrence M|Chow, Christina R|Raza, Sania S|Bentrem, David J|Ebine, Kazumi|Munshi, Hidayatullah G
PMID: 24807963
Journal: Sci Rep. 2015 Mar 25;5:9489.
Title: GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1.
Author: Kumar, Krishan|Raza, Sania S|Knab, Lawrence M|Chow, Christina R|Kwok, Benjamin|Bentrem, David J|Popovic, Relja|Ebine, Kazumi|Licht, Jonathan D|Munshi, Hidayatullah G
PMID: 25807524
Journal: Clin Cancer Res. 2016 Aug 15;22(16):4259-70.
Title: Regulation of GLI Underlies a Role for BET Bromodomains in Pancreatic Cancer Growth and the Tumor Microenvironment.
Author: Huang, Yinshi|Nahar, Sabikun|Nakagawa, Akifumi|Fernandez-Barrena, Maite G|Mertz, Jennifer A|Bryant, Barbara M|Adams, Curtis E|Mino-Kenudson, Mari|Von Alt, Kate N|Chang, Kevin|Conery, Andrew R|Hatton, Charlie|Sims, Robert J 3rd|Fernandez-Zapico, Martin E|W
PMID: 27169995
Journal: JCI Insight. 2017 Feb 9;2(3):e88032.
Title: BET inhibitors block pancreatic stellate cell collagen I production and attenuate fibrosis in vivo.
Author: Kumar, Krishan|DeCant, Brian T|Grippo, Paul J|Hwang, Rosa F|Bentrem, David J|Ebine, Kazumi|Munshi, Hidayatullah G
PMID: 28194432
Journal: Cancer Lett. 2017 May 28;394:76-87.
Title: Bromodomain inhibitors, JQ1 and I-BET 762, as potential therapies for pancreatic cancer.
Author: Leal, Ana S|Williams, Charlotte R|Royce, Darlene B|Pioli, Patricia A|Sporn, Michael B|Liby, Karen T
PMID: 28254412
Journal: Cancer Cell. 2018 Mar 12;33(3):512-526.e8.
Title: Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors.
Author: Andricovich, Jaclyn|Perkail, Stephanie|Kai, Yan|Casasanta, Nicole|Peng, Weiqun|Tzatsos, Alexandros
PMID: 29533787
Journal: J Exp Clin Cancer Res. 2018 Sep 10;37(1):224.
Title: FBP1 loss contributes to BET inhibitors resistance by undermining c-Myc expression in pancreatic ductal adenocarcinoma.
Author: Wang, Bo|Fan, Ping|Zhao, Jingyuan|Wu, Heyu|Jin, Xin|Wu, Heshui
PMID: 30201002