Primary Site >> Pancreatic Cancer
Gene >> DNER
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Ref: BET bromodomain inhibitors block growth of pancreatic cancer cells in three-dimensional collagen. PMID: 24807963 |
Ref: GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1. PMID: 25807524 |
Ref: Regulation of GLI Underlies a Role for BET Bromodomains in Pancreatic Cancer Growth and the Tumor Microenvironment. PMID: 27169995 |
Ref: BET inhibitors block pancreatic stellate cell collagen I production and attenuate fibrosis in vivo. PMID: 28194432 Ref: Bromodomain inhibitors, JQ1 and I-BET 762, as potential therapies for pancreatic cancer. PMID: 28254412 |
Ref: Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors. PMID: 29533787 Ref: FBP1 loss contributes to BET inhibitors resistance by undermining c-Myc expression in pancreatic ductal adenocarcinoma. PMID: 30201002 |