Primary Site >> Colorectal Cancer

Gene >> DLL4

Journal: Int J Mol Med. 2006 Apr;17(4):681-5.
Title: Notch ligand, JAG1, is evolutionarily conserved target of canonical WNT signaling pathway in progenitor cells.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 16525728
Journal: Int J Oncol. 2007 Jan;30(1):247-51.
Title: Notch signaling in gastrointestinal tract (review).
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17143535
Journal: Cancer Res. 2009 Feb 15;69(4):1314-23.
Title: Cross-talk between tumor and endothelial cells involving the Notch3-Dll4 interaction marks escape from tumor dormancy.
Author: Indraccolo, Stefano|Minuzzo, Sonia|Masiero, Massimo|Pusceddu, Irene|Persano, Luca|Moserle, Lidia|Reboldi, Andrea|Favaro, Elena|Mecarozzi, Marco|Di Mario, Giuseppina|Screpanti, Isabella|Ponzoni, Maurilio|Doglioni, Claudio|Amadori, Alberto
PMID: 19208840
Journal: Br J Cancer. 2009 Nov 17;101(10):1749-57.
Title: Expression of delta-like ligand 4 (Dll4) and markers of hypoxia in colon cancer.
Author: Jubb, A M|Turley, H|Moeller, H C|Steers, G|Han, C|Li, J-L|Leek, R|Tan, E Y|Singh, B|Mortensen, N J|Noguera-Troise, I|Pezzella, F|Gatter, K C|Thurston, G|Fox, S B|Harris, A L
PMID: 19844231
Journal: Cancer Res. 2011 Mar 1;71(5):1520-5.
Title: Anti-DLL4 inhibits growth and reduces tumor-initiating cell frequency in colorectal tumors with oncogenic KRAS mutations.
Author: Fischer, Marcus|Yen, Wan-Ching|Kapoun, Ann M|Wang, Min|O'Young, Gilbert|Lewicki, John|Gurney, Austin|Hoey, Timothy
PMID: 21193546
Journal: J Pathol. 2011 Aug;224(4):448-60.
Title: Notch3 signalling promotes tumour growth in colorectal cancer.
Author: Serafin, Valentina|Persano, Luca|Moserle, Lidia|Esposito, Giovanni|Ghisi, Margherita|Curtarello, Matteo|Bonanno, Laura|Masiero, Massimo|Ribatti, Domenico|Sturzl, Michael|Naschberger, Elisabeth|Croner, Roland S|Jubb, Adrian M|Harris, Adrian L|Koeppen, Hart
PMID: 21598247
Journal: J Natl Cancer Inst. 2011 Dec 7;103(23):1778-98.
Title: Delta-like ligand 4-notch blockade and tumor radiation response.
Author: Liu, Stanley K|Bham, Saif A S|Fokas, Emmanouil|Beech, John|Im, Jaehong|Cho, Song|Harris, Adrian L|Muschel, Ruth J
PMID: 22010178
Journal: PLoS One. 2012;7(4):e34758.
Title: Genetic polymorphism in a VEGF-independent angiogenesis gene ANGPT1 and overall survival of colorectal cancer patients after surgical resection.
Author: Dai, Jingyao|Wan, Shaogui|Zhou, Feng|Myers, Ronald E|Guo, Xu|Li, Bingshan|Fu, Xiaoying|Palazzo, Juan P|Dou, Kefeng|Yang, Hushan|Xing, Jinliang
PMID: 22496856
Journal: Oncotarget. 2013 Nov;4(11):1948-62.
Title: Selective targeting of human colon cancer stem-like cells by the mTOR inhibitor Torin-1.
Author: Francipane, Maria Giovanna|Lagasse, Eric
PMID: 24185040
Journal: PLoS One. 2014 Apr 15;9(4):e93888.
Title: Dll4-notch signalling blockade synergizes combined ultrasound-stimulated microbubble and radiation therapy in human colon cancer xenografts.
Author: El Kaffas, Ahmed|Nofiele, Joris|Giles, Anoja|Cho, Song|Liu, Stanley K|Czarnota, Gregory J
PMID: 24736631
Journal: Lab Invest. 2014 Nov;94(11):1296-308.
Title: Antagonism of Ang-Tie2 and Dll4-Notch signaling has opposing effects on tumor endothelial cell proliferation, evidenced by a new flow cytometry method.
Author: Payton, Marc|Jun, Toni|Wayne, William|Yu, Dongyin|Manoukian, Raffi|Chung, Grace|Zhang, Nancy|Sun, Ji-Rong|Kaplan-Lefko, Paula|Scully, Sheila|Van, Gwyneth|Radinsky, Robert|Kendall, Richard|Oliner, Jonathan|Coxon, Angela
PMID: 25243900
Journal: Cancer Res. 2014 Apr 1;74(7):2106-18.
Title: NOTCH3 signaling regulates MUSASHI-1 expression in metastatic colorectal cancer cells.
Author: Pasto, Anna|Serafin, Valentina|Pilotto, Giorgia|Lago, Claudia|Bellio, Chiara|Trusolino, Livio|Bertotti, Andrea|Hoey, Timothy|Plateroti, Michelina|Esposito, Giovanni|Pinazza, Marica|Agostini, Marco|Nitti, Donato|Amadori, Alberto|Indraccolo, Stefano
PMID: 24525742
Journal: J Int Med Res. 2015 Aug;43(4):535-43.
Title: Expression of delta-like 4 (Drosophila) and vascular endothelial growth factor A in colon cancer and association with tumour angiogenesis.
Author: Zheng, Yongbin|Hao, Zhinan|Ding, Yu|Wang, Qiushuang|Li, Shengbo|Xiao, Gaochun|Luo, Haiping|Shi, Qiang|Tong, Shilun
PMID: 26111775
Journal: Int J Clin Exp Med. 2015 Apr 15;8(4):6510-6. eCollection 2015.
Title: HDAC5 promotes colorectal cancer cell proliferation by up-regulating DLL4 expression.
Author: He, Ping|Liang, Jiexiong|Shao, Tiansong|Guo, Yang|Hou, Yingchen|Li, Yang
PMID: 26131280
Journal: BMC Cancer. 2015 Sep 22;15:643.
Title: Angiogenesis-related protein expression in bevacizumab-treated metastatic colorectal cancer: NOTCH1 detrimental to overall survival.
Author: Paiva, Tadeu Ferreira Jr|de Jesus, Victor Hugo Fonseca|Marques, Raul Amorim|da Costa, Alexandre Andre Balieiro Anastacio|de Macedo, Mariana Petaccia|Peresi, Patricia Maria|Damascena, Aline|Rossi, Benedito Mauro|Begnami, Maria Dirlei|de Lima, Vladmir Claud
PMID: 26394830
Journal: Oncotarget. 2017 Jan 3;8(1):552-564.
Title: Inhibition of the transcriptional repressor complex Bcl-6/BCoR induces endothelial sprouting but does not promote tumor growth.
Author: Buchberger, Elisabeth|Payrhuber, Dietmar|El Harchi, Miriam|Zagrapan, Branislav|Scheuba, Katharina|Zommer, Anna|Bugyik, Edina|Dome, Balazs|Kral, Julia Barbara|Schrottmaier, Waltraud Cornelia|Schabbauer, Gernot|Petzelbauer, Peter|Groger, Marion|Bilban, Mart
PMID: 27880939
Journal: BMC Cancer. 2017 Jan 13;17(1):50.
Title: Delta-like 4/Notch signaling promotes Apc (Min/+) tumor initiation through angiogenic and non-angiogenic related mechanisms.
Author: Badenes, Marina|Trindade, Alexandre|Pissarra, Hugo|Lopes-da-Costa, Luis|Duarte, Antonio
PMID: 28086833
Journal: Anticancer Drugs. 2017 Jun;28(5):531-539.
Title: Metformin depresses overactivated Notch1/Hes1 signaling in colorectal cancer patients with type 2 diabetes mellitus.
Author: Yang, Bin|Huang, Can-Ze|Yu, Tao|Zhou, Sheng-Ning|Liu, Qi|Liu, Gao-Jie|Chen, Shuang|Han, Fang-Hai
PMID: 28177944
Journal: PLoS One. 2018 Jun 7;13(6):e0198099.
Title: Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer.
Author: Jarzabek, Monika A|Proctor, William R|Vogt, Jennifer|Desai, Rupal|Dicker, Patrick|Cain, Gary|Raja, Rajiv|Brodbeck, Jens|Stevens, Dale|van der Stok, Eric P|Martens, John W M|Verhoef, Cornelis|Hegde, Priti S|Byrne, Annette T|Tarrant, Jacqueline M
PMID: 29879147
Journal: Sci Rep. 2018 Jun 13;8(1):9032.
Title: Treating the Intestine with Oral ApoA-I Mimetic Tg6F Reduces Tumor Burden in Mouse Models of Metastatic Lung Cancer.
Author: Chattopadhyay, Arnab|Yang, Xinying|Mukherjee, Pallavi|Sulaiman, Dawoud|Fogelman, Hannah R|Grijalva, Victor|Dubinett, Steven|Wasler, Tonya C|Paul, Manash K|Salehi-Rad, Ramin|Mack, Julia J|Iruela-Arispe, M Luisa|Navab, Mohamad|Fogelman, Alan M|Reddy, Sriniv
PMID: 29899427