Primary Site >> Colorectal Cancer

Gene >> DKK2

Journal: Carcinogenesis. 2007 Dec;28(12):2459-66. Epub 2007 Aug 3.
Title: Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.
Author: Sato, Hironobu|Suzuki, Hiromu|Toyota, Minoru|Nojima, Masanori|Maruyama, Reo|Sasaki, Shigeru|Takagi, Hideyasu|Sogabe, Yohei|Sasaki, Yasushi|Idogawa, Masashi|Sonoda, Tomoko|Mori, Mitsuru|Imai, Kohzoh|Tokino, Takashi|Shinomura, Yasuhisa
PMID: 17675336
Journal: Oncol Lett. 2013 Dec;6(6):1687-1692.
Title: DNA methylation as an epigenetic biomarker in colorectal cancer.
Author: Silva, Tiago Donizetti|Vidigal, Veronica Marques|Felipe, Aledson Vitor|DE Lima, Jacqueline Miranda|Neto, Ricardo Artigiani|Saad, Sarhan Sidney|Forones, Nora Manoukian
PMID: 24260063
Journal: Pharmacogenomics J. 2014 Apr;14(2):142-50.
Title: Association of common gene variants in the WNT/beta-catenin pathway with colon cancer recurrence.
Author: Paez, D|Gerger, A|Zhang, W|Yang, D|Labonte, M J|Benhanim, L|Kahn, M|Lenz, F|Lenz, C|Ning, Y|Wakatsuki, T|Loupakis, F|Lenz, H-J
PMID: 23817222
Journal: Clin Cancer Res. 2014 Mar 15;20(6):1687-97.
Title: A functional germline variant in GLI1 implicates hedgehog signaling in clinical outcome of stage II and III colon carcinoma patients.
Author: Szkandera, Joanna|Pichler, Martin|Absenger, Gudrun|Stotz, Michael|Weissmueller, Melanie|Samonigg, Hellmut|Asslaber, Martin|Lax, Sigurd|Leitner, Gerhard|Winder, Thomas|Renner, Wilfried|Gerger, Armin
PMID: 24470513
Journal: Epigenomics. 2014 Apr;6(2):179-91.
Title: DNA methylation changes in genes frequently mutated in sporadic colorectal cancer and in the DNA repair and Wnt/beta-catenin signaling pathway genes.
Author: Farkas, Sanja A|Vymetalkova, Veronika|Vodickova, Ludmila|Vodicka, Pavel|Nilsson, Torbjorn K
PMID: 24811787
Journal: Cancer Prev Res (Phila). 2014 Oct;7(10):1002-10.
Title: Analysis of DNA methylation in bowel lavage fluid for detection of colorectal cancer.
Author: Harada, Taku|Yamamoto, Eiichiro|Yamano, Hiro-o|Nojima, Masanori|Maruyama, Reo|Kumegawa, Kohei|Ashida, Masami|Yoshikawa, Kenjiro|Kimura, Tomoaki|Harada, Eiji|Takagi, Ryo|Tanaka, Yoshihito|Aoki, Hironori|Nishizono, Masayo|Nakaoka, Michiko|Tsuyada, Akihiro|N
PMID: 25139296
Journal: BMC Cancer. 2014 Nov 29;14:891.
Title: Boosting Wnt activity during colorectal cancer progression through selective hypermethylation of Wnt signaling antagonists.
Author: Silva, Ana-Luisa|Dawson, Sarah N|Arends, Mark J|Guttula, Kiran|Hall, Nigel|Cameron, Ewen A|Huang, Tim H-M|Brenton, James D|Tavare, Simon|Bienz, Mariann|Ibrahim, Ashraf E K
PMID: 25432628
Journal: Cancer Biol Ther. 2016 Nov;17(11):1126-1138.
Title: MiR-339 and especially miR-766 reactivate the expression of tumor suppressor genes in colorectal cancer cell lines through DNA methyltransferase 3B gene inhibition.
Author: Afgar, Ali|Fard-Esfahani, Pezhman|Mehrtash, Amirhosein|Azadmanesh, Kayhan|Khodarahmi, Farnaz|Ghadir, Mahdis|Teimoori-Toolabi, Ladan
PMID: 27668319
Journal: Cell Physiol Biochem. 2017;41(5):1709-1724.
Title: Dickkopf-Related Protein 2 is Epigenetically Inactivated and Suppresses Colorectal Cancer Growth and Tumor Metastasis by Antagonizing Wnt/beta-Catenin Signaling.
Author: Wang, Can|Yue, Yujuan|Shao, Bianfei|Qiu, Zhu|Mu, Junhao|Tang, Jun|Han, Xiaofan|Xiang, Tingxiu|Ren, Guosheng
PMID: 28365691
Journal: Clin Epigenetics. 2017 May 18;9:55.
Title: Analysis of the DNA methylation level of cancer-related genes in colorectal cancer and the surrounding normal mucosa.
Author: Sugai, Tamotsu|Yoshida, Masakazu|Eizuka, Makoto|Uesugii, Noriyuki|Habano, Wataru|Otsuka, Kouki|Sasaki, Akira|Yamamoto, Eiichiro|Matsumoto, Takayuki|Suzuki, Hiromu
PMID: 28533824
Journal: Nat Med. 2018 Mar;24(3):262-270.
Title: DKK2 imparts tumor immunity evasion through beta-catenin-independent suppression of cytotoxic immune-cell activation.
Author: Xiao, Qian|Wu, Jibo|Wang, Wei-Jia|Chen, Shiyang|Zheng, Yingxia|Yu, Xiaoqing|Meeth, Katrina|Sahraei, Mahnaz|Bothwell, Alfred L M|Chen, Lieping|Bosenberg, Marcus|Chen, Jianfeng|Sexl, Veronika|Sun, Le|Li, Lin|Tang, Wenwen|Wu, Dianqing
PMID: 29431745
Journal: BMC Cancer. 2018 Jun 27;18(1):695.
Title: Gene promoter and exon DNA methylation changes in colon cancer development - mRNA expression and tumor mutation alterations.
Author: Molnar, Bela|Galamb, Orsolya|Peterfia, Balint|Wichmann, Barnabas|Csabai, Istvan|Bodor, Andras|Kalmar, Alexandra|Szigeti, Krisztina Andrea|Bartak, Barbara Kinga|Nagy, Zsofia Brigitta|Valcz, Gabor|Patai, Arpad V|Igaz, Peter|Tulassay, Zsolt
PMID: 29945573
Journal: J Biomol Struct Dyn. 2018 Jul 23:1-46.
Title: In Silico studying of the whole protein structure and dynamics of Dickkopf family members showed that N terminal domain of Dickkopf 2 in contrary to other Dickkopfs facilitates its interaction with Low Density Lipoprotein Receptor Related Protein 5/6.
Author: Sadeghi, Solmaz|Poorebrahim, Mansour|Rahimi, Hamzeh|Karimipoor, Morteza|Azadmanesh, Kayhan|Khorramizadeh, Mohammad Reza|Teimoori-Toolabi, Ladan
PMID: 30035709