Primary Site >> Colorectal Cancer

Gene >> DKK1

Journal: Cancer Cell. 2004 Nov;6(5):497-506.
Title: An autocrine mechanism for constitutive Wnt pathway activation in human cancer cells.
Author: Bafico, Anna|Liu, Guizhong|Goldin, Luba|Harris, Violaine|Aaronson, Stuart A
PMID: 15542433
Journal: Oncogene. 2005 Feb 3;24(6):1098-103.
Title: The Wnt antagonist DICKKOPF-1 gene is a downstream target of beta-catenin/TCF and is downregulated in human colon cancer.
Author: Gonzalez-Sancho, Jose Manuel|Aguilera, Oscar|Garcia, Jose Miguel|Pendas-Franco, Natalia|Pena, Cristina|Cal, Santiago|Garcia de Herreros, Antonio|Bonilla, Felix|Munoz, Alberto
PMID: 15592505
Journal: Oncol Rep. 2005 Sep;14(3):783-7.
Title: Comparative genomics on SFRP2 orthologs.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 16077992
Journal: Int J Oncol. 2005 Sep;27(3):861-5.
Title: Comparative genomics on SFRP1 orthologs.
Author: Katoh, Yuriko|Katoh, Masaru
PMID: 16077939
Journal: Int J Mol Med. 2006 Jan;17(1):171-5.
Title: WNT antagonist, SFRP1, is Hedgehog signaling target.
Author: Katoh, Yuriko|Katoh, Masaru
PMID: 16328026
Journal: Oncogene. 2006 Jul 6;25(29):4116-21. Epub 2006 Feb 20.
Title: Epigenetic inactivation of the Wnt antagonist DICKKOPF-1 (DKK-1) gene in human colorectal cancer.
Author: Aguilera, O|Fraga, M F|Ballestar, E|Paz, M F|Herranz, M|Espada, J|Garcia, J M|Munoz, A|Esteller, M|Gonzalez-Sancho, J M
PMID: 16491118
Journal: Int J Cancer. 2006 Oct 15;119(8):1837-42.
Title: Mutations within Wnt pathway genes in sporadic colorectal cancers and cell lines.
Author: Suraweera, Nirosha|Robinson, James|Volikos, Emmanuoil|Guenther, Thomas|Talbot, Ian|Tomlinson, Ian|Silver, Andrew
PMID: 16708370
Journal: Int J Mol Med. 2007 Mar;19(3):529-33.
Title: Comparative integromics on FZD7 orthologs: conserved binding sites for PU.1, SP1, CCAAT-box and TCF/LEF/SOX transcription factors within 5'-promoter region of mammalian FZD7 orthologs.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17273804
Journal: Int J Oncol. 2007 May;30(5):1273-7.
Title: Conserved POU/OCT- and GATA-binding sites in 5'-flanking promoter region of mammalian WNT8B orthologs.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 17390031
Journal: Carcinogenesis. 2007 Sep;28(9):1877-84. Epub 2007 Apr 21.
Title: The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells.
Author: Aguilera, Oscar|Pena, Cristina|Garcia, Jose Miguel|Larriba, Maria Jesus|Ordonez-Moran, Paloma|Navarro, Diego|Barbachano, Antonio|Lopez de Silanes, Isabel|Ballestar, Esteban|Fraga, Mario F|Esteller, Manel|Gamallo, Carlos|Bonilla, Felix|Gonzalez-Sancho, Jos
PMID: 17449905
Journal: J Cell Sci. 2007 Aug 1;120(Pt 15):2672-82. Epub 2007 Jul 17.
Title: Mechanical force modulates global gene expression and beta-catenin signaling in colon cancer cells.
Author: Avvisato, Christopher L|Yang, Xiang|Shah, Salim|Hoxter, Becky|Li, Weiqun|Gaynor, Richard|Pestell, Richard|Tozeren, Aydin|Byers, Stephen W
PMID: 17635998
Journal: Carcinogenesis. 2007 Dec;28(12):2459-66. Epub 2007 Aug 3.
Title: Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.
Author: Sato, Hironobu|Suzuki, Hiromu|Toyota, Minoru|Nojima, Masanori|Maruyama, Reo|Sasaki, Shigeru|Takagi, Hideyasu|Sogabe, Yohei|Sasaki, Yasushi|Idogawa, Masashi|Sonoda, Tomoko|Mori, Mitsuru|Imai, Kohzoh|Tokino, Takashi|Shinomura, Yasuhisa
PMID: 17675336
Journal: Cell Cycle. 2007 Nov 1;6(21):2625-7. Epub 2007 Aug 13.
Title: Turning the tables: Myc activates Wnt in breast cancer.
Author: Cowling, Victoria H|Cole, Michael D
PMID: 17726380
Journal: World J Gastroenterol. 2008 May 7;14(17):2702-14.
Title: Transcriptional silencing of Dickkopf gene family by CpG island hypermethylation in human gastrointestinal cancer.
Author: Maehata, Tadateru|Taniguchi, Hiroaki|Yamamoto, Hiroyuki|Nosho, Katsuhiko|Adachi, Yasushi|Miyamoto, Nobuki|Miyamoto, Chie|Akutsu, Noriyuki|Yamaoka, Satoshi|Itoh, Fumio
PMID: 18461655
Journal: Br J Cancer. 2008 Jul 8;99(1):136-42.
Title: Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa.
Author: Belshaw, N J|Elliott, G O|Foxall, R J|Dainty, J R|Pal, N|Coupe, A|Garg, D|Bradburn, D M|Mathers, J C|Johnson, I T
PMID: 18542073
Journal: J Gastrointest Surg. 2008 Oct;12(10):1745-53.
Title: Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia.
Author: Dhir, Mashaal|Montgomery, Elizabeth A|Glockner, Sabine C|Schuebel, Kornel E|Hooker, Craig M|Herman, James G|Baylin, Stephen B|Gearhart, Susan L|Ahuja, Nita
PMID: 18716850
Journal: Anticancer Res. 2008 Sep-Oct;28(5A):2613-23.
Title: Vitamin D and Wnt/beta-catenin pathway in colon cancer: role and regulation of DICKKOPF genes.
Author: Pendas-Franco, Natalia|Aguilera, Oscar|Pereira, Fabio|Gonzalez-Sancho, Jose Manuel|Munoz, Alberto
PMID: 19035286
Journal: Cancer Lett. 2009 Apr 18;276(2):152-9.
Title: Dickkopf-4 is frequently down-regulated and inhibits growth of colorectal cancer cells.
Author: Baehs, Sebastian|Herbst, Andreas|Thieme, Susanne E|Perschl, Claudia|Behrens, Andrea|Scheel, Silvio|Jung, Andreas|Brabletz, Thomas|Goke, Burkhard|Blum, Helmut|Kolligs, Frank T
PMID: 19059704
Journal: Genome Med. 2009 Sep 4;1(9):83.
Title: Networking of differentially expressed genes in human cancer cells resistant to methotrexate.
Author: Selga, Elisabet|Oleaga, Carlota|Ramirez, Sara|de Almagro, M Cristina|Noe, Veronique|Ciudad, Carlos J
PMID: 19732436
Journal: Clin Chem. 2009 Sep;55(9):1656-64.
Title: Clinical significance and prognostic value of serum Dickkopf-1 concentrations in patients with lung cancer.
Author: Sheng, Shi Le|Huang, Gang|Yu, Bin|Qin, Wen Xin
PMID: 19628661
Journal: Int J Cancer. 2009 Jul 15;125(2):297-307.
Title: Selective inhibition of proliferation in colorectal carcinoma cell lines expressing mutant APC or activated B-Raf.
Author: Zhang, Hui-Hua|Walker, Francesca|Kiflemariam, Sara|Whitehead, Robert H|Williams, David|Phillips, Wayne A|Mikeska, Thomas|Dobrovic, Alexander|Burgess, Antony W
PMID: 19378335
Journal: J Pathol. 2010 Mar;220(4):475-89.
Title: A five-gene signature as a potential predictor of metastasis and survival in colorectal cancer.
Author: Hao, Jun-Mei|Chen, Juan-Zhi|Sui, Hong-Mei|Si-Ma, Xue-Qing|Li, Guang-Qiu|Liu, Chao|Li, Ji-Liang|Ding, Yan-Qing|Li, Jian-Ming
PMID: 20077526
Journal: Carcinogenesis. 2010 Jun;31(6):1158-63.
Title: Patterns of DNA methylation in individual colonic crypts reveal aging and cancer-related field defects in the morphologically normal mucosa.
Author: Belshaw, Nigel J|Pal, Nandita|Tapp, Henri S|Dainty, Jack R|Lewis, Michael P N|Williams, Mark R|Lund, Elizabeth K|Johnson, Ian T
PMID: 20395289
Journal: Chin J Cancer. 2010 Sep;29(9):810-5.
Title: 5-Fluorouracil upregulates the activity of Wnt signaling pathway in CD133-positive colon cancer stem-like cells.
Author: Deng, Yan-Hong|Pu, Xing-Xiang|Huang, Mei-Jin|Xiao, Jian|Zhou, Jia-Ming|Lin, Tong-Yu|Lin, Edward H
PMID: 20800023
Journal: Oncotarget. 2010 Nov;1(7):596-605.
Title: The class I HDAC inhibitor MGCD0103 induces cell cycle arrest and apoptosis in colon cancer initiating cells by upregulating Dickkopf-1 and non-canonical Wnt signaling.
Author: Sikandar, Shaheen|Dizon, Diana|Shen, Xiling|Li, Zuomei|Besterman, Jeffery|Lipkin, Steven M
PMID: 21317455
Journal: Carcinogenesis. 2011 May;32(5):741-7.
Title: Promoter methylation of Wnt antagonists DKK1 and SFRP1 is associated with opposing tumor subtypes in two large populations of colorectal cancer patients.
Author: Rawson, James B|Manno, Michael|Mrkonjic, Miralem|Daftary, Darshana|Dicks, Elizabeth|Buchanan, Daniel D|Younghusband, H Banfield|Parfrey, Patrick S|Young, Joanne P|Pollett, Aaron|Green, Roger C|Gallinger, Steven|McLaughlin, John R|Knight, Julia A|Bapat, Bh
PMID: 21304055
Journal: Biochim Biophys Acta. 2011 Jul;1809(7):306-15.
Title: Dickkopf homolog 1, a Wnt signaling antagonist, is transcriptionally up-regulated via an ATF4-independent and MAPK/ERK-dependent pathway following amino acid deprivation.
Author: Zhou, Dan|Zhang, Yukun|Pan, Yuan-Xiang|Chen, Hong
PMID: 21683813
Journal: J Investig Med. 2011 Aug;59(6):947-50.
Title: Relationship between clinicopathologic variables and serum and tissue levels of dickkopf-1 in patients with rectal cancer.
Author: Kemik, Ozgur|Kemik, Ahu Sarbay|Sumer, Aziz|Begenik, Huseyin|Purisa, Sevm|Tuzun, Sefa|Kotan, Cetn
PMID: 21712726
Journal: Mol Biol Cell. 2011 Sep;22(18):3344-54.
Title: S100A4-induced cell motility and metastasis is restricted by the Wnt/beta-catenin pathway inhibitor calcimycin in colon cancer cells.
Author: Sack, Ulrike|Walther, Wolfgang|Scudiero, Dominic|Selby, Mike|Aumann, Jutta|Lemos, Clara|Fichtner, Iduna|Schlag, Peter M|Shoemaker, Robert H|Stein, Ulrike
PMID: 21795396
Journal: Asian Pac J Cancer Prev. 2011;12(12):3187-9.
Title: Lack of diagnostic potential of Dickkopf-1 in colon and rectum cancers.
Author: Soydinc, Hilal Oguz|Duranyildiz, Derya|Camlica, Hakan|Oral, Ethem Nezih|Yasasever, Vildan
PMID: 22471451
Journal: Nutr Cancer. 2012;64(7):919-28.
Title: Vitamin D intake is negatively associated with promoter methylation of the Wnt antagonist gene DKK1 in a large group of colorectal cancer patients.
Author: Rawson, James B|Sun, Zhouyu|Dicks, Elizabeth|Daftary, Darshana|Parfrey, Patrick S|Green, Roger C|Gallinger, Steven|McLaughlin, John R|Wang, Peizhong P|Knight, Julia A|Bapat, Bharati
PMID: 22966878
Journal: Cancer Sci. 2012 Apr;103(4):828-35.
Title: Dickkopf-1 inhibits epithelial-mesenchymal transition of colon cancer cells and contributes to colon cancer suppression.
Author: Qi, Lisha|Sun, Baocun|Liu, Zhiyong|Li, Hui|Gao, Jun|Leng, Xue
PMID: 22321022
Journal: PLoS One. 2012;7(7):e40955.
Title: Genistein affects histone modifications on Dickkopf-related protein 1 (DKK1) gene in SW480 human colon cancer cell line.
Author: Wang, Huan|Li, Qian|Chen, Hong
PMID: 22815877
Journal: Biochem Biophys Res Commun. 2013 Feb 22;431(4):746-52.
Title: 2,3,6-Trisubstituted quinoxaline derivative, a small molecule inhibitor of the Wnt/beta-catenin signaling pathway, suppresses cell proliferation and enhances radiosensitivity in A549/Wnt2 cells.
Author: Lee, Sang Bum|Gong, Young-Dae|Park, Young In|Dong, Mi-Sook
PMID: 23348226
Journal: Nan Fang Yi Ke Da Xue Xue Bao. 2013 Jun;33(6):923-5, 933.
Title: [Expression of Dickkopf-1 in human colon carcinoma cell lines].
Author: Yu, Qian|Yang, Lei|Ding, Yanqing|Zhao, Zhen|Liu, Huiping
PMID: 23803213
Journal: PLoS One. 2013 Jul 26;8(7):e70077.
Title: Lysine-specific demethylase 1 (LSD1/KDM1A) contributes to colorectal tumorigenesis via activation of the Wnt/beta-catenin pathway by down-regulating Dickkopf-1 (DKK1) [corrected].
Author: Huang, Zebin|Li, Shangze|Song, Wei|Li, Xin|Li, Qinshan|Zhang, Zeyan|Han, Yongqing|Zhang, Xiaodong|Miao, Shiying|Du, Runlei|Wang, Linfang
PMID: 23922913
Journal: PLoS One. 2013 Oct 8;8(10):e76865.
Title: Cancer-predicting gene expression changes in colonic mucosa of Western diet fed Mlh1+/- mice.
Author: Pussila, Marjaana|Sarantaus, Laura|Dermadi Bebek, Denis|Valo, Satu|Reyhani, Nima|Ollila, Saara|Paivarinta, Essi|Peltomaki, Paivi|Mutanen, Marja|Nystrom, Minna
PMID: 24204690
Journal: Tumour Biol. 2014 Apr;35(4):3145-54.
Title: Prognostic significance of dickkopf-1 overexpression in solid tumors: a meta-analysis.
Author: Liu, Yanqiong|Tang, Weizhong|Xie, Li|Wang, Jian|Deng, Yan|Peng, Qiliu|Zhai, Limin|Li, Shan|Qin, Xue
PMID: 24258111
Journal: PLoS One. 2014 Jan 10;9(1):e85340.
Title: High expression of IGFBP7 in fibroblasts induced by colorectal cancer cells is co-regulated by TGF-beta and Wnt signaling in a Smad2/3-Dvl2/3-dependent manner.
Author: Rao, Cui|Lin, Shan-Li|Ruan, Wen-Jing|Wen, Huan|Wu, Dan-Ju|Deng, Hong
PMID: 24427302
Journal: Eur Rev Med Pharmacol Sci. 2014;18(12):1742-7.
Title: The role of preoperative serum levels for Dickkopf-related protein 1 as a potential marker of tumor invasion in patients with stage II and III colon cancer.
Author: Gurluler, E|Tumay, L V|Guner, O S|Kucukmetin, N T|Hizli, B|Zorluoglu, A
PMID: 24992617
Journal: Cancer Lett. 2014 Nov 28;354(2):417-26.
Title: SDF-1/CXCR4 promotes epithelial-mesenchymal transition and progression of colorectal cancer by activation of the Wnt/beta-catenin signaling pathway.
Author: Hu, Ting-Hua|Yao, Yu|Yu, Shuo|Han, Li-Li|Wang, Wen-Juan|Guo, Hui|Tian, Tao|Ruan, Zhi-Pin|Kang, Xiao-Min|Wang, Jing|Wang, Shu-Hong|Nan, Ke-Jun
PMID: 25150783
Journal: J Exp Clin Cancer Res. 2014 Dec 11;33:107.
Title: Wnt3a expression is associated with epithelial-mesenchymal transition and promotes colon cancer progression.
Author: Qi, Lisha|Sun, Baocun|Liu, Zhiyong|Cheng, Runfen|Li, Yixian|Zhao, Xiulan
PMID: 25499541
Journal: Oncotarget. 2015 Oct 6;6(30):29357-74.
Title: Positive feedback loop of hepatoma-derived growth factor and beta-catenin promotes carcinogenesis of colorectal cancer.
Author: Lian, Jiayan|Tang, Jianming|Shi, Huijuan|Li, Hui|Zhen, Tiantian|Xie, Wenlin|Zhang, Fenfen|Yang, Yang|Han, Anjia
PMID: 26296979
Journal: Int J Mol Sci. 2015 Aug 10;16(8):18564-79.
Title: Wnt3a Promotes the Vasculogenic Mimicry Formation of Colon Cancer via Wnt/beta-Catenin Signaling.
Author: Qi, Lisha|Song, Wangzhao|Liu, Zhiyong|Zhao, Xiulan|Cao, Wenfeng|Sun, Baocun
PMID: 26266404
Journal: BMC Med Genomics. 2015 Aug 12;8:49.
Title: FoxM1 transactivates PTTG1 and promotes colorectal cancer cell migration and invasion.
Author: Zheng, Yun|Guo, Jinjun|Zhou, Jin|Lu, Jinjian|Chen, Qi|Zhang, Cui|Qing, Chen|Koeffler, H Philip|Tong, Yunguang
PMID: 26264222
Journal: Oncotarget. 2015 Mar 20;6(8):5903-17.
Title: Nuclear DICKKOPF-1 as a biomarker of chemoresistance and poor clinical outcome in colorectal cancer.
Author: Aguilera, Oscar|Gonzalez-Sancho, Jose Manuel|Zazo, Sandra|Rincon, Raul|Fernandez, Agustin F|Tapia, Olga|Canals, Francesc|Morte, Beatriz|Calvanese, Vincenzo|Orgaz, Jose L|Niell, Nuria|Aguilar, Susana|Freije, Jose M|Grana, Osvaldo|Pisano, David G|Borrero, A
PMID: 25788273
Journal: Mol Carcinog. 2015 Dec;54(12):1748-57.
Title: EYA4 Acts as a New Tumor Suppressor Gene in Colorectal Cancer.
Author: Kim, Sung-Jin|Tae, Chung Hyun|Hong, Sung Noh|Min, Byung-Hoon|Chang, Dong Kyung|Rhee, Poong-Lyul|Kim, Jae J|Kim, Hee Cheol|Kim, Duk-Hwan|Kim, Young-Ho
PMID: 25620232
Journal: Histopathology. 2015 Aug;67(2):158-66.
Title: Dickkopf-1 expression is down-regulated during the colorectal adenoma-carcinoma sequence and correlates with reduced microvessel density and VEGF expression.
Author: Liu, Zhiyong|Sun, Baocun|Qi, Lisha|Li, Yixian|Zhao, Xiulan|Zhang, Danfang|Zhang, Yanhui
PMID: 24916146
Journal: J Exp Clin Cancer Res. 2015 Jul 25;34:71.
Title: Vitamin D3 enhances the tumouricidal effects of 5-Fluorouracil through multipathway mechanisms in azoxymethane rat model of colon cancer.
Author: Refaat, Bassem|El-Shemi, Adel Galal|Kensara, Osama Adnan|Mohamed, Amr Mohamed|Idris, Shakir|Ahmad, Jawwad|Khojah, Athar
PMID: 26205949
Journal: Cancer Prev Res (Phila). 2016 Jun;9(6):491-501.
Title: Paricalcitol Enhances the Chemopreventive Efficacy of 5-Fluorouracil on an Intermediate-Term Model of Azoxymethane-Induced Colorectal Tumors in Rats.
Author: El-Shemi, Adel Galal|Refaat, Bassem|Kensara, Osama Adnan|Mohamed, Amr Mohamed|Idris, Shakir|Ahmad, Jawwad
PMID: 27020656
Journal: Epigenetics. 2016 Aug 2;11(8):588-602.
Title: Aberrant DNA methylation of WNT pathway genes in the development and progression of CIMP-negative colorectal cancer.
Author: Galamb, Orsolya|Kalmar, Alexandra|Peterfia, Balint|Csabai, Istvan|Bodor, Andras|Ribli, Dezso|Krenacs, Tibor|Patai, Arpad V|Wichmann, Barnabas|Bartak, Barbara Kinga|Toth, Kinga|Valcz, Gabor|Spisak, Sandor|Tulassay, Zsolt|Molnar, Bela
PMID: 27245242
Journal: Drug Des Devel Ther. 2016 Jul 11;10:2239-53.
Title: Thymoquinone subdues tumor growth and potentiates the chemopreventive effect of 5-fluorouracil on the early stages of colorectal carcinogenesis in rats.
Author: Kensara, Osama Adnan|El-Shemi, Adel Galal|Mohamed, Amr Mohamed|Refaat, Bassem|Idris, Shakir|Ahmad, Jawwad
PMID: 27468227
Journal: Oncogenesis. 2017 Apr 3;6(4):e308.
Title: Methylation of WNT target genes AXIN2 and DKK1 as robust biomarkers for recurrence prediction in stage II colon cancer.
Author: Kandimalla, R|Linnekamp, J F|van Hooff, S|Castells, A|Llor, X|Andreu, M|Jover, R|Goel, A|Medema, J P
PMID: 28368388
Journal: Oncol Lett. 2017 Dec;14(6):7653-7668.
Title: Therapeutic strategies against cancer stem cells in human colorectal cancer.
Author: Szarynska, Magdalena|Olejniczak, Agata|Kobiela, Jaroslaw|Spychalski, Piotr|Kmiec, Zbigniew
PMID: 29250169
Journal: Eur Rev Med Pharmacol Sci. 2017 Nov;21(21):4844-4852.
Title: miR-590-3p promotes colon cancer cell proliferation via Wnt/beta-catenin signaling pathway by inhibiting WIF1 and DKK1.
Author: Feng, Z-Y|Xu, X-H|Cen, D-Z|Luo, C-Y|Wu, S-B
PMID: 29164578
Journal: Int J Mol Med. 2017 Sep;40(3):587-606.
Title: Molecular genetics and targeted therapy of WNT-related human diseases (Review).
Author: Katoh, Masuko|Katoh, Masaru
PMID: 28731148
Journal: PLoS One. 2017 Jul 14;12(7):e0179888.
Title: Extracellular inhibitors can attenuate tumorigenic Wnt pathway activity in adenomatous polyposis coli mutants: Predictions of a validated mathematical model.
Author: Hochman, Gili|Halevi-Tobias, Karin|Kogan, Yuri|Agur, Zvia
PMID: 28708837
Journal: Tumour Biol. 2017 May;39(5):1010428317705504.
Title: Suppression subtractive hybridization identified differentially expressed genes in colorectal cancer: microRNA-451a as a novel colorectal cancer-related gene.
Author: Xu, Ke|Zhang, Yuan-Yuan|Han, Bin|Bai, Yang|Xiong, Yao|Song, Yi|Zhou, Li-Ming
PMID: 28468585
Journal: Am J Transl Res. 2017 Feb 15;9(2):774-790. eCollection 2017.
Title: Thymoquinone potentiates chemoprotective effect of Vitamin D3 against colon cancer: a pre-clinical finding.
Author: Mohamed, Amr M|Refaat, Bassem A|El-Shemi, Adel G|Kensara, Osama A|Ahmad, Jawwad|Idris, Shakir
PMID: 28337306
Journal: Cell Signal. 2017 Jun;34:38-46.
Title: CSN5/JAB1 suppresses the WNT inhibitor DKK1 in colorectal cancer cells.
Author: Jumpertz, Sandra|Hennes, Thomas|Asare, Yaw|Schutz, Anke K|Bernhagen, Jurgen
PMID: 28229932
Journal: Gut. 2017 Apr;66(4):666-682.
Title: ZEB1-induced tumourigenesis requires senescence inhibition via activation of DKK1/mutant p53/Mdm2/CtBP and repression of macroH2A1.
Author: de Barrios, Oriol|Gyorffy, Balazs|Fernandez-Acenero, Maria Jesus|Sanchez-Tillo, Ester|Sanchez-Moral, Lidia|Siles, Laura|Esteve-Arenys, Anna|Roue, Gael|Casal, Jose I|Darling, Douglas S|Castells, Antoni|Postigo, Antonio
PMID: 27965283
Journal: Oncotarget. 2018 Mar 30;9(24):17066-17077.
Title: Ferric citrate and ferric EDTA but not ferrous sulfate drive amphiregulin-mediated activation of the MAP kinase ERK in gut epithelial cancer cells.
Author: Scheers, Nathalie M|Pereira, Dora I A|Faria, Nuno|Powell, Jonathan J
PMID: 29682205
Journal: Int J Mol Med. 2018 Aug;42(2):713-725.
Title: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
Author: Katoh, Masaru
PMID: 29786110
Journal: J Biomol Struct Dyn. 2018 Jul 23:1-46.
Title: In Silico studying of the whole protein structure and dynamics of Dickkopf family members showed that N terminal domain of Dickkopf 2 in contrary to other Dickkopfs facilitates its interaction with Low Density Lipoprotein Receptor Related Protein 5/6.
Author: Sadeghi, Solmaz|Poorebrahim, Mansour|Rahimi, Hamzeh|Karimipoor, Morteza|Azadmanesh, Kayhan|Khorramizadeh, Mohammad Reza|Teimoori-Toolabi, Ladan
PMID: 30035709
Journal: Histol Histopathol. 2018 Sep 19:18043.
Title: LncRNA HOTTIP mediated DKK1 downregulation confers metastasis and invasion in colorectal cancer cells.
Author: Rui, Yiqi|Hu, Mingchao|Wang, Peng|Zhang, Chuanqiang|Xu, Hua|Li, Yuanzhong|Zhang, Yu|Gu, Jianchun|Wang, Qiang
PMID: 30229808