Primary Site >> Liver Cancer

Gene >> DICER1

Journal: Gastroenterology. 2009 Jun;136(7):2304-2315.e1-4.
Title: Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis.
Author: Sekine, Shigeki|Ogawa, Reiko|Ito, Rie|Hiraoka, Nobuyoshi|McManus, Michael T|Kanai, Yae|Hebrok, Matthias
PMID: 19272382
Journal: BMC Mol Biol. 2009 Feb 2;10:5.
Title: A noncoding RNA gene on chromosome 10p15.3 may function upstream of hTERT.
Author: Miura, Norimasa|Sato, Reina|Tsukamoto, Tomoe|Shimizu, Mika|Kabashima, Hiroko|Takeda, Miho|Takahashi, Shunsaku|Harada, Tomomi|West, James E|Drabkin, Harry|Mejia, Jose E|Shiota, Goshi|Murawaki, Yoshikazu|Virmani, Arvind|Gazdar, Adi F|Oshimura, Mitsuo|Hasega
PMID: 19187532
Journal: Med Oncol. 2011 Sep;28(3):804-9.
Title: Down-regulation of Dicer in hepatocellular carcinoma.
Author: Wu, Jin-Feng|Shen, Wei|Liu, Nian-Zhou|Zeng, Gui-Li|Yang, Mei|Zuo, Guo-Qing|Gan, Xiu-Ni|Ren, Hong|Tang, Kai-Fu
PMID: 20405249
Journal: PLoS One. 2011;6(9):e24359.
Title: Receptor for activated protein kinase C: requirement for efficient microRNA function and reduced expression in hepatocellular carcinoma.
Author: Otsuka, Motoyuki|Takata, Akemi|Yoshikawa, Takeshi|Kojima, Kentaro|Kishikawa, Takahiro|Shibata, Chikako|Takekawa, Mutsuhiro|Yoshida, Haruhiko|Omata, Masao|Koike, Kazuhiko
PMID: 21935400
Journal: Oncogene. 2012 Dec 6;31(49):5081-9.
Title: Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivo.
Author: Leucci, E|Zriwil, A|Gregersen, L H|Jensen, K T|Obad, S|Bellan, C|Leoncini, L|Kauppinen, S|Lund, A H
PMID: 22310293
Journal: Zhonghua Yu Fang Yi Xue Za Zhi. 2012 Jun;46(6):533-7.
Title: [Correlation between tag single nucleotide polymorphisms of microRNA regulatory genes and the genetic susceptibility of primary liver cancer].
Author: Li, Yu-chun|Song, Chun-hua|Yang, Wen-jie|Dai, Li-ping|Wang, Peng|Shi, Jian-xiang|Zhang, Jian-ying|Wang, Kai-juan
PMID: 22943901
Journal: Hepatology. 2013 May;57(5):1906-18.
Title: Argonaute2 promotes tumor metastasis by way of up-regulating focal adhesion kinase expression in hepatocellular carcinoma.
Author: Cheng, Na|Li, Yandong|Han, Ze-Guang
PMID: 23258480
Journal: Cancer Sci. 2013 May;104(5):543-51.
Title: Downregulation of the microRNA biogenesis components and its association with poor prognosis in hepatocellular carcinoma.
Author: Kitagawa, Noriyuki|Ojima, Hidenori|Shirakihara, Takuya|Shimizu, Hiroko|Kokubu, Akiko|Urushidate, Tomoko|Totoki, Yasushi|Kosuge, Tomoo|Miyagawa, Shinichi|Shibata, Tatsuhiro
PMID: 23398123
Journal: Mol Carcinog. 2013 Nov;52 Suppl 1:E148-54.
Title: Potentially functional genetic variants in microRNA processing genes and risk of HBV-related hepatocellular carcinoma.
Author: Liu, Li|An, Jiaze|Liu, Jibin|Wen, Juan|Zhai, Xiangjun|Liu, Yao|Pan, Shandong|Jiang, Jie|Wen, Yang|Liu, Zheng|Zhang, Yixin|Chen, Jianguo|Xing, Jinliang|Ji, Guozhong|Shen, Hongbing|Hu, Zhibin|Fan, Zhining
PMID: 23868705
Journal: PLoS One. 2013 Dec 17;8(12):e82751.
Title: Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells.
Author: Chen, Yen-Ju|Thang, Mike W C|Chan, Yu-Tzu|Huang, Yu-Feng|Ma, Nianhan|Yu, Alice L|Wu, Chung-Yi|Hu, Miao-Lin|Chiu, Kuo Ping
PMID: 24358224
Journal: Mol Ther. 2014 Jan;22(1):92-101.
Title: Knockdown of beta-catenin with dicer-substrate siRNAs reduces liver tumor burden in vivo.
Author: Dudek, Henryk|Wong, Darren H|Arvan, Rokhand|Shah, Anee|Wortham, Kathleen|Ying, Bo|Diwanji, Rohan|Zhou, Wei|Holmes, Benjamin|Yang, Hailin|Cyr, Wendy A|Zhou, Yi|Shah, Aalok|Farkiwala, Ruchir|Lee, Michael|Li, Yiting|Rettig, Garrett R|Collingwood, Michael A|B
PMID: 24089139
Journal: J Appl Toxicol. 2014 Dec;34(12):1409-17.
Title: Absence of mature microRNAs inactivates the response of gene expression to carcinogenesis induced by N-ethyl-N-nitrosourea in mouse liver.
Author: Luan, Yang|Qi, Xinming|Xu, Liang|Ren, Jin|Chen, Tao
PMID: 24478143
Journal: PLoS One. 2014 Mar 27;9(3):e92791.
Title: Single nucleotide polymorphisms of microRNA processing machinery genes and outcome of hepatocellular carcinoma.
Author: Liu, Shuang|An, Jie|Lin, Jianhong|Liu, Yanli|Bao, Lidao|Zhang, Wen|Zhao, Jian-Jun
PMID: 24676133
Journal: Carcinogenesis. 2014 Sep;35(9):2127-33.
Title: MicroRNA-581 promotes hepatitis B virus surface antigen expression by targeting Dicer and EDEM1.
Author: Wang, Yu-Qun|Ren, Yong-Feng|Song, Yi-Jiang|Xue, Yong-Feng|Zhang, Xue-Jiao|Cao, Su-Ting|Deng, Zhu-Jun|Wu, Jianmin|Chen, Li|Li, Guiling|Shi, Ke-Qing|Chen, Yong-Ping|Ren, Hong|Huang, Ai-Long|Tang, Kai-Fu
PMID: 24913918
Journal: Biochem Biophys Res Commun. 2015 Jul 31;463(3):389-94.
Title: Ablation of Dicer leads to widespread perturbation of signaling pathways.
Author: Sahasrabuddhe, Nandini A|Huang, Tai-Chung|Kumar, Praveen|Yang, Yi|Ghosh, Bidyut|Leach, Steven D|Chaerkady, Raghothama|Pandey, Akhilesh
PMID: 26032504
Journal: Sci Rep. 2015 Nov 16;5:16732.
Title: miR-34a screened by miRNA profiling negatively regulates Wnt/beta-catenin signaling pathway in Aflatoxin B1 induced hepatotoxicity.
Author: Zhu, Liye|Gao, Jing|Huang, Kunlun|Luo, Yunbo|Zhang, Boyang|Xu, Wentao
PMID: 26567713
Journal: World J Gastroenterol. 2015 Jun 7;21(21):6591-603.
Title: Loss of Dicer1 impairs hepatocyte survival and leads to chronic inflammation and progenitor cell activation.
Author: Lu, Xu-Feng|Zhou, Yong-Jie|Zhang, Lei|Ji, Hong-Jie|Li, Li|Shi, Yu-Jun|Bu, Hong
PMID: 26074697
Journal: J Hepatol. 2015 Aug;63(2):408-19.
Title: MicroRNA-221 governs tumor suppressor HDAC6 to potentiate malignant progression of liver cancer.
Author: Bae, Hyun Jin|Jung, Kwang Hwa|Eun, Jung Woo|Shen, Qingyu|Kim, Hyung Seok|Park, Se Jin|Shin, Woo Chan|Yang, Hee Doo|Park, Won Sang|Lee, Jung Young|Nam, Suk Woo
PMID: 25817558
Journal: Oncol Lett. 2016 Jun;11(6):3961-3966.
Title: Prognostic significance of Dicer expression in hepatocellular carcinoma.
Author: Zhang, L I|Wang, Cuiju|Liu, Shufeng|Zhao, Yufei|Liu, Chao|Guo, Zhanjun
PMID: 27313724
Journal: PLoS One. 2016 Sep 9;11(9):e0162279.
Title: Variation in the Dicer and RAN Genes Are Associated with Survival in Patients with Hepatocellular Carcinoma.
Author: Kim, Mi Na|Kim, Jung Oh|Lee, Seung Min|Park, Hana|Lee, Ju Ho|Rim, Kyu Sung|Hwang, Seong Gyu|Kim, Nam Keun
PMID: 27611467
Journal: Cancer Lett. 2016 Dec 28;383(2):282-294.
Title: Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells.
Author: Kuo, Tsang-Chih|Chen, Chi-Kuan|Hua, Kuo-Tai|Yu, Pei|Lee, Wei-Jiunn|Chen, Min-Wei|Jeng, Yung-Ming|Chien, Ming-Hsien|Kuo, Kuang-Tai|Hsiao, Michael|Kuo, Min-Liang
PMID: 27725225
Journal: Hepatol Res. 2017 Aug;47(9):845-853.
Title: Genetic variant in DICER gene is associated with prognosis of hepatocellular carcinoma in a Chinese cohort.
Author: Wang, Zhao|Wang, Jiaxiang|Wang, Qun|Wang, Jiachen|Yuan, Jiaxiang|Si, Yaqing
PMID: 27670743
Journal: Hepatology. 2017 May;65(5):1581-1599.
Title: Targeting beta-catenin in hepatocellular cancers induced by coexpression of mutant beta-catenin and K-Ras in mice.
Author: Tao, Junyan|Zhang, Rong|Singh, Sucha|Poddar, Minakshi|Xu, Emily|Oertel, Michael|Chen, Xin|Ganesh, Shanthi|Abrams, Marc|Monga, Satdarshan P
PMID: 27981621
Journal: J Hepatol. 2017 Apr;66(4):734-742.
Title: Germline and somatic DICER1 mutations in familial and sporadic liver tumors.
Author: Caruso, Stefano|Calderaro, Julien|Letouze, Eric|Nault, Jean-Charles|Couchy, Gabrielle|Boulai, Anais|Luciani, Alain|Zafrani, Elie-Serge|Bioulac-Sage, Paulette|Seror, Olivier|Imbeaud, Sandrine|Zucman-Rossi, Jessica
PMID: 28012864
Journal: J Virol. 2017 Apr 28;91(10). pii: JVI.01919-16.
Title: Hepatitis B Virus-Encoded MicroRNA Controls Viral Replication.
Author: Yang, Xi|Li, Hongfeng|Sun, Huahui|Fan, Hongxia|Hu, Yaqi|Liu, Min|Li, Xin|Tang, Hua
PMID: 28148795
Journal: Clin Cancer Res. 2017 Jul 15;23(14):3896-3905.
Title: Hypoxia Causes Downregulation of Dicer in Hepatocellular Carcinoma, Which Is Required for Upregulation of Hypoxia-Inducible Factor 1alpha and Epithelial-Mesenchymal Transition.
Author: Ibrahim, Ahmed Atef|Schmithals, Christian|Kowarz, Erik|Koberle, Verena|Kakoschky, Bianca|Pleli, Thomas|Kollmar, Otto|Nitsch, Scarlett|Waidmann, Oliver|Finkelmeier, Fabian|Zeuzem, Stefan|Korf, Horst-Werner|Schmid, Tobias|Weigert, Andreas|Kronenberger, Bern
PMID: 28167508
Journal: Chin Med Sci J. 2017 Apr 10;32(1):34-3.
Title: microRNA-18a Promotes Cell Migration and Invasion Through Inhibiting Dicer l Expression in Hepatocellular Carcinoma In Vitro.
Author: Zhang, Xiufen|Yu, Bo|Zhang, Fuzheng|Guo, Zijian|Li, Lihua
PMID: 28399983
Journal: Sci Rep. 2017 May 18;7(1):2070.
Title: The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2.
Author: Wang, Yuan|Chen, Fuquan|Yang, Zhe|Zhao, Man|Zhang, Shuqin|Gao, Yuen|Feng, Jinyan|Yang, Guang|Zhang, Weiying|Ye, Lihong|Zhang, Xiaodong
PMID: 28522832
Journal: Hepatology. 2018 Jun;67(6):2414-2429.
Title: MicroRNA-21 and Dicer are dispensable for hepatic stellate cell activation and the development of liver fibrosis.
Author: Caviglia, Jorge Matias|Yan, Jun|Jang, Myoung-Kuk|Gwak, Geum-Youn|Affo, Silvia|Yu, Lexing|Olinga, Peter|Friedman, Richard A|Chen, Xin|Schwabe, Robert F
PMID: 29091291
Journal: Oncotarget. 2018 Jan 9;9(19):14815-14827.
Title: RNA-binding protein AUF1 suppresses miR-122 biogenesis by down-regulating Dicer1 in hepatocellular carcinoma.
Author: Wu, Xia|Yang, Yingzhuo|Huang, Yike|Chen, Yang|Wang, Tianying|Wu, Shuo|Tong, Lei|Wang, Yan|Lin, Lexun|Hao, Meili|Zhong, Zhao-Hua|Zhang, Fengmin|Zhao, Wenran
PMID: 29599909
Journal: Genomics Proteomics Bioinformatics. 2018 Apr;16(2):120-126.
Title: The Role of Exportin-5 in MicroRNA Biogenesis and Cancer.
Author: Wu, Ke|He, Juan|Pu, Wenchen|Peng, Yong
PMID: 29723684