Primary Site >> Liver Cancer
Gene >> DICER1
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Ref: A noncoding RNA gene on chromosome 10p15.3 may function upstream of hTERT. PMID: 19187532 Ref: Disruption of Dicer1 induces dysregulated fetal gene expression and promotes hepatocarcinogenesis. PMID: 19272382 |
Ref: Down-regulation of Dicer in hepatocellular carcinoma. PMID: 20405249 Ref: Receptor for activated protein kinase C: requirement for efficient microRNA function and reduced expression in hepatocellular carcinoma. PMID: 21935400 |
Ref: Inhibition of miR-9 de-represses HuR and DICER1 and impairs Hodgkin lymphoma tumour outgrowth in vivo. PMID: 22310293 Ref: [Correlation between tag single nucleotide polymorphisms of microRNA regulatory genes and the genetic susceptibility of primary liver cancer]. PMID: 22943901 |
Ref: Argonaute2 promotes tumor metastasis by way of up-regulating focal adhesion kinase expression in hepatocellular carcinoma. PMID: 23258480 Ref: Downregulation of the microRNA biogenesis components and its association with poor prognosis in hepatocellular carcinoma. PMID: 23398123 Ref: Potentially functional genetic variants in microRNA processing genes and risk of HBV-related hepatocellular carcinoma. PMID: 23868705 Ref: Global assessment of Antrodia cinnamomea-induced microRNA alterations in hepatocarcinoma cells. PMID: 24358224 |
Ref: Knockdown of beta-catenin with dicer-substrate siRNAs reduces liver tumor burden in vivo. PMID: 24089139 Ref: Absence of mature microRNAs inactivates the response of gene expression to carcinogenesis induced by N-ethyl-N-nitrosourea in mouse liver. PMID: 24478143 Ref: Single nucleotide polymorphisms of microRNA processing machinery genes and outcome of hepatocellular carcinoma. PMID: 24676133 Ref: MicroRNA-581 promotes hepatitis B virus surface antigen expression by targeting Dicer and EDEM1. PMID: 24913918 |
Ref: MicroRNA-221 governs tumor suppressor HDAC6 to potentiate malignant progression of liver cancer. PMID: 25817558 Ref: Ablation of Dicer leads to widespread perturbation of signaling pathways. PMID: 26032504 Ref: Loss of Dicer1 impairs hepatocyte survival and leads to chronic inflammation and progenitor cell activation. PMID: 26074697 Ref: miR-34a screened by miRNA profiling negatively regulates Wnt/beta-catenin signaling pathway in Aflatoxin B1 induced hepatotoxicity. PMID: 26567713 |
Ref: Prognostic significance of Dicer expression in hepatocellular carcinoma. PMID: 27313724 Ref: Variation in the Dicer and RAN Genes Are Associated with Survival in Patients with Hepatocellular Carcinoma. PMID: 27611467 Ref: Glutaminase 2 stabilizes Dicer to repress Snail and metastasis in hepatocellular carcinoma cells. PMID: 27725225 |
Ref: Genetic variant in DICER gene is associated with prognosis of hepatocellular carcinoma in a Chinese cohort. PMID: 27670743 Ref: Targeting beta-catenin in hepatocellular cancers induced by coexpression of mutant beta-catenin and K-Ras in mice. PMID: 27981621 Ref: Germline and somatic DICER1 mutations in familial and sporadic liver tumors. PMID: 28012864 Ref: Hepatitis B Virus-Encoded MicroRNA Controls Viral Replication. PMID: 28148795 Ref: Hypoxia Causes Downregulation of Dicer in Hepatocellular Carcinoma, Which Is Required for Upregulation of Hypoxia-Inducible Factor 1alpha and Epithelial-Mesenchymal Transition. PMID: 28167508 Ref: microRNA-18a Promotes Cell Migration and Invasion Through Inhibiting Dicer l Expression in Hepatocellular Carcinoma In Vitro. PMID: 28399983 Ref: The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3'UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2. PMID: 28522832 |
Ref: MicroRNA-21 and Dicer are dispensable for hepatic stellate cell activation and the development of liver fibrosis. PMID: 29091291 Ref: RNA-binding protein AUF1 suppresses miR-122 biogenesis by down-regulating Dicer1 in hepatocellular carcinoma. PMID: 29599909 Ref: The Role of Exportin-5 in MicroRNA Biogenesis and Cancer. PMID: 29723684 |