Literatures

Primary Site >> Colorectal Cancer

Gene >> DIABLO

1.
Journal:	Tumori. 1995 May-Jun;81(3):157-63.
Title:	A multicenter study of colorectal adenomas. Rationale, objectives, methods and characteristics of the study cohort. The Multicentric Study of Colorectal Adenomas (SMAC) Workgroup.
Author:
PMID:	7571020

2.
Journal:	Cancer Res. 2003 Apr 1;63(7):1483-9.
Title:	Bax plays a pivotal role in thapsigargin-induced apoptosis of human colon cancer HCT116 cells by controlling Smac/Diablo and Omi/HtrA2 release from mitochondria.
Author:	Yamaguchi, Hirohito\|Bhalla, Kapil\|Wang, Hong-Gang
PMID:	12670894

3.
Journal:	Cancer Res. 2003 Aug 15;63(16):5118-25.
Title:	Rottlerin sensitizes colon carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis via uncoupling of the mitochondria independent of protein kinase C.
Author:	Tillman, David M\|Izeradjene, Kamel\|Szucs, Kinga Szekely\|Douglas, Leslie\|Houghton, Janet A
PMID:	12941843

4.
Journal:	Oncogene. 2003 Aug 7;22(32):4953-63.
Title:	The proteasome inhibitor PS-341 overcomes TRAIL resistance in Bax and caspase 9-negative or Bcl-xL overexpressing cells.
Author:	Johnson, Thomas R\|Stone, Kimberley\|Nikrad, Malti\|Yeh, Tammie\|Zong, Wei-Xing\|Thompson, Craig B\|Nesterov, Alexandre\|Kraft, Andrew S
PMID:	12902978

5.
Journal:	APMIS. 2003 Mar;111(3):382-8.
Title:	Immunohistochemical analysis of Smac/DIABLO expression in human carcinomas and sarcomas.
Author:	Yoo, Nam Jin\|Kim, Hong Sug\|Kim, Su Young\|Park, Won Sang\|Park, Cho Hyun\|Jeon, Hae Myung\|Jung, Eun Sun\|Lee, Jung Young\|Lee, Sug Hyung
PMID:	12752217

6.
Journal:	J Clin Epidemiol. 2003 Mar;56(3):209-14.
Title:	Interobserver agreement in the histologic diagnosis of colorectal polyps. the experience of the multicenter adenoma colorectal study (SMAC).
Author:	Costantini, Massimo\|Sciallero, Stefania\|Giannini, Augusto\|Gatteschi, Beatrice\|Rinaldi, Paolo\|Lanzanova, Giuseppe\|Bonelli, Luigina\|Casetti, Tino\|Bertinelli, Elisabetta\|Giuliani, Orietta\|Castiglione, Guido\|Mantellini, Paola\|Naldoni, Carlo\|Bruzzi, Paolo
PMID:	12725874

7.
Journal:	Carcinogenesis. 2004 Feb;25(2):179-87.
Title:	Ectopic expression of Hsp70 confers resistance and silencing its expression sensitizes human colon cancer cells to curcumin-induced apoptosis.
Author:	Rashmi, Ramachandran\|Kumar, Santhosh\|Karunagaran, Devarajan
PMID:	14604899

8.
Journal:	Carcinogenesis. 2004 Oct;25(10):1867-77. Epub 2004 Jun 17.
Title:	Ectopic expression of Bcl-XL or Ku70 protects human colon cancer cells (SW480) against curcumin-induced apoptosis while their down-regulation potentiates it.
Author:	Rashmi, Ramachandran\|Kumar, Santhosh\|Karunagaran, Devarajan
PMID:	15205359

9.
Journal:	Proc Natl Acad Sci U S A. 2004 Nov 30;101(48):16897-902. Epub 2004 Nov 19.
Title:	SMAC/Diablo-dependent apoptosis induced by nonsteroidal antiinflammatory drugs (NSAIDs) in colon cancer cells.
Author:	Kohli, Manu\|Yu, Jian\|Seaman, Craig\|Bardelli, Alberto\|Kinzler, Kenneth W\|Vogelstein, Bert\|Lengauer, Christoph\|Zhang, Lin
PMID:	15557007

10.
Journal:	Clin Cancer Res. 2004 Dec 15;10(24):8284-92.
Title:	Tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis is inhibited by Bcl-2 but restored by the small molecule Bcl-2 inhibitor, HA 14-1, in human colon cancer cells.
Author:	Sinicrope, Frank A\|Penington, Robert C\|Tang, Xi Ming
PMID:	15623604

11.
Journal:	Carcinogenesis. 2005 Apr;26(4):713-23. Epub 2005 Jan 20.
Title:	Human colon cancer cells lacking Bax resist curcumin-induced apoptosis and Bax requirement is dispensable with ectopic expression of Smac or downregulation of Bcl-XL.
Author:	Rashmi, Ramachandran\|Kumar, Santhosh\|Karunagaran, Devarajan
PMID:	15661804

12.
Journal:	Mol Cancer Res. 2005 Jan;3(1):21-31.
Title:	Apolipoprotein l6, a novel proapoptotic Bcl-2 homology 3-only protein, induces mitochondria-mediated apoptosis in cancer cells.
Author:	Liu, Zhihe\|Lu, Huimei\|Jiang, Zeyu\|Pastuszyn, Andrzej\|Hu, Chien-an A
PMID:	15671246

13.
Journal:	Int J Oncol. 2005 Apr;26(4):1069-77.
Title:	Uncoupling of oxidative phosphorylation and Smac/DIABLO release are not sufficient to account for induction of apoptosis by sulindac sulfide in human colorectal cancer cells.
Author:	Daouphars, Mikael\|Koufany, Meriem\|Benani, Alexandre\|Marchal, Sophie\|Merlin, Jean-Louis\|Netter, Patrick\|Jouzeau, Jean-Yves
PMID:	15754004

14.
Journal:	Korean J Gastroenterol. 2005 Apr;45(4):285-93.
Title:	[Frequent epigenetic inactivation of XAF1 by promotor hypermethylation in human colon cancers].
Author:	Jang, Jae Young\|Kim, Hyo Jong\|Chi, Sung-Gil\|Lee, Kil Yeon\|Nam, Ki Deuk\|Kim, Nam Hoon\|Lee, Sang Kil\|Joo, Kwang Ro\|Dong, Seok Ho\|Kim, Byung-Ho\|Chang, Young Woon\|Lee, Joung Il\|Chang, Rin
PMID:	15843754

15.
Journal:	Carcinogenesis. 2005 Oct;26(10):1716-30. Epub 2005 May 19.
Title:	Justicidin A decreases the level of cytosolic Ku70 leading to apoptosis in human colorectal cancer cells.
Author:	Lee, Jenq-Chang\|Lee, Chao-Hung\|Su, Chun-Li\|Huang, Chung-Wei\|Liu, Hsiao-Sheng\|Lin, Chun-Nan\|Won, Shen-Jeu
PMID:	15905197

16.
Journal:	Cancer Biol Ther. 2005 Jul;4(7):781-6. Epub 2005 Jul 6.
Title:	Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation.
Author:	Zhu, Hongbo\|Guo, Wei\|Zhang, Lidong\|Wu, Shuhong\|Teraishi, Fuminori\|Davis, John J\|Dong, Fengqin\|Fang, Bingliang
PMID:	16082182

17.
Journal:	Cancer Res. 2005 Aug 15;65(16):7436-45.
Title:	Reactive oxygen species regulate caspase activation in tumor necrosis factor-related apoptosis-inducing ligand-resistant human colon carcinoma cell lines.
Author:	Izeradjene, Kamel\|Douglas, Leslie\|Tillman, David M\|Delaney, Addison B\|Houghton, Janet A
PMID:	16103097

18.
Journal:	Pathol Oncol Res. 2006;12(3):133-42. Epub 2006 Sep 23.
Title:	Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria.
Author:	Nagy, Katalin\|Szekely-Szuts, Kinga\|Izeradjene, Kamel\|Douglas, Leslie\|Tillman, Mike\|Barti-Juhasz, Helga\|Dominici, Massimo\|Spano, Carlotta\|Luca Cervo, Gian\|Conte, Pierfranco\|Houghton, Janet A\|Mihalik, Rudolf\|Kopper, Laszlo\|Petak, Istvan
PMID:	16998592

19.
Journal:	Oncogene. 2007 Jun 21;26(29):4189-98. Epub 2007 Jan 22.
Title:	SMAC/Diablo mediates the proapoptotic function of PUMA by regulating PUMA-induced mitochondrial events.
Author:	Yu, J\|Wang, P\|Ming, L\|Wood, M A\|Zhang, L
PMID:	17237824

20.
Journal:	J Surg Res. 2007 Sep;142(1):184-94. Epub 2007 Jul 2.
Title:	Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF.
Author:	Huerta, Sergio\|Heinzerling, John H\|Anguiano-Hernandez, Yu-Mei\|Huerta-Yepez, Sara\|Lin, Jeffrey\|Chen, David\|Bonavida, Benjamin\|Livingston, Edward H
PMID:	17603079

21.
Journal:	Anticancer Agents Med Chem. 2007 Jul;7(4):467-73.
Title:	Smac/DIABLO and colon cancer.
Author:	Anguiano-Hernandez, Y M\|Chartier, A\|Huerta, S
PMID:	17630921

22.
Journal:	J Med Food. 2007 Dec;10(4):581-6.
Title:	Induction of apoptosis in HT-29 colon cancer cells by phloretin.
Author:	Park, So Young\|Kim, Eun Ji\|Shin, Hyun-Kyung\|Kwon, Dae Young\|Kim, Myung Sunny\|Surh, Young-Joon\|Park, Jung Han Yoon
PMID:	18158826

23.
Journal:	J Nutr. 2007 Jan;137(1):31-6.
Title:	Activation of caspase-8 contributes to 3,3'-Diindolylmethane-induced apoptosis in colon cancer cells.
Author:	Kim, Eun Ji\|Park, So Young\|Shin, Hyun-Kyung\|Kwon, Dae Young\|Surh, Young-Joon\|Park, Jung Han Yoon
PMID:	17182797

24.
Journal:	Ai Zheng. 2008 Feb;27(2):178-82.
Title:	[Smac as a predictive marker of tumor response to preoperative radiotherapy in rectal cancer].
Author:	Pan, Zhi-Zhong\|Lin, Jun-Zhong\|Wan, De-Sen
PMID:	18279617

25.
Journal:	J Proteome Res. 2008 Aug;7(8):3254-66.
Title:	The response of human colonocytes to folate deficiency in vitro: functional and proteomic analyses.
Author:	Duthie, Susan J\|Mavrommatis, Yiannis\|Rucklidge, Gary\|Reid, Martin\|Duncan, Gary\|Moyer, Mary P\|Pirie, Lynn P\|Bestwick, Charles S
PMID:	18597513

26.
Journal:	Oncogene. 2008 Oct 9;27(46):6012-22.
Title:	A mitochondrial block and expression of XIAP lead to resistance to TRAIL-induced apoptosis during progression to metastasis of a colon carcinoma.
Author:	Ndozangue-Touriguine, O\|Sebbagh, M\|Merino, D\|Micheau, O\|Bertoglio, J\|Breard, J
PMID:	18560353

27.
Journal:	Biochem Biophys Res Commun. 2008 Jul 18;372(1):236-42.
Title:	Morusin induces apoptosis and suppresses NF-kappaB activity in human colorectal cancer HT-29 cells.
Author:	Lee, Jenq-Chang\|Won, Shen-Jeu\|Chao, Chien-Lin\|Wu, Feng-Ling\|Liu, Hsiao-Sheng\|Ling, Pin\|Lin, Chun-Nan\|Su, Chun-Li
PMID:	18485277

28.
Journal:	Sci China C Life Sci. 2008 Jan;51(1):66-71.
Title:	Ceramide induces release of mitochondrial proapoptotic proteins in caspase-dependent and -independent manner in HT-29 cells.
Author:	Zhang, XiaoFeng\|Li, BaiXiang\|Zhang, Yang\|Liu, JiaRen
PMID:	18176793

29.
Journal:	Cancer Res. 2008 Jan 1;68(1):276-84.
Title:	SMAC mimetics sensitize nonsteroidal anti-inflammatory drug-induced apoptosis by promoting caspase-3-mediated cytochrome c release.
Author:	Bank, Alexander\|Wang, Peng\|Du, Chunying\|Yu, Jian\|Zhang, Lin
PMID:	18172320

30.
Journal:	Oncogene. 2008 Jan 31;27(6):763-74. Epub 2007 Jul 23.
Title:	MnSOD protects colorectal cancer cells from TRAIL-induced apoptosis by inhibition of Smac/DIABLO release.
Author:	Mohr, A\|Buneker, C\|Gough, R P\|Zwacka, R M
PMID:	17653087

31.
Journal:	Mol Cell Pharmacol. 2009 Jan 1;1(2):92-97.
Title:	Sulindac Sulfide Differentially Induces Apoptosis in Smac-Proficient and -Deficient Human Colon Cancer Cells.
Author:	Shi, Jingxue\|He, Qin\|An, Jie\|Sun, Hong\|Huang, Ying\|Sheikh, M Saeed
PMID:	20419043

32.
Journal:	Mol Cell Pharmacol. 2009;1(1):23-28.
Title:	Smac deficiency affects endoplasmic reticulum stress-induced apoptosis in human colon cancer cells.
Author:	He, Qin\|Shi, Jingxue\|Jones, Samantha\|An, Jie\|Liu, Yuxin\|Huang, Ying\|Sheikh, M Saeed
PMID:	20209078

33.
Journal:	J Med Food. 2009 Oct;12(5):952-8.
Title:	trans-10,cis-12 Conjugated linoleic acid induces depolarization of mitochondrial membranes in HT-29 human colon cancer cells: a possible mechanism for induction of apoptosis.
Author:	Cho, Han Jin\|Kwon, Gyoo Taik\|Park, Jung Han Yoon
PMID:	19857056

34.
Journal:	Cancer Prev Res (Phila). 2009 Aug;2(8):732-42.
Title:	Regulation of colorectal cancer cell apoptosis by the n-3 polyunsaturated fatty acids Docosahexaenoic and Eicosapentaenoic.
Author:	Giros, Anna\|Grzybowski, Mike\|Sohn, Vanessa R\|Pons, Elisenda\|Fernandez-Morales, Jessica\|Xicola, Rosa M\|Sethi, Puja\|Grzybowski, Jessica\|Goel, Ajay\|Boland, C Richard\|Gassull, Miquel A\|Llor, Xavier
PMID:	19638488

35.
Journal:	Oncol Rep. 2009 Aug;22(2):295-303.
Title:	Immunoexpression of inhibitors of apoptosis proteins and their antagonist SMAC/DIABLO in colorectal carcinoma: correlation with apoptotic index, cellular proliferation and prognosis.
Author:	De Oliveira Lima, Flavio\|De Oliveira Costa, Henrique\|Barrezueta, Luis Fernando Mesias\|Fujiyama Oshima, Celina Tizuko\|Silva, Jose Antonio Jr\|Gomes, Thiago Simao\|Pinheiro, Nathanael Jr\|Neto, Ricardo Artigiani\|Franco, Marcello
PMID:	19578769

36.
Journal:	Biochem Pharmacol. 2009 May 1;77(9):1487-96.
Title:	A rice bran polyphenol, cycloartenyl ferulate, elicits apoptosis in human colorectal adenocarcinoma SW480 and sensitizes metastatic SW620 cells to TRAIL-induced apoptosis.
Author:	Kong, Carrie K L\|Lam, W S\|Chiu, Lawrence C M\|Ooi, Vincent E C\|Sun, Samuel S M\|Wong, Yum-Shing
PMID:	19426686

37.
Journal:	Am J Physiol Gastrointest Liver Physiol. 2009 May;296(5):G1060-8.
Title:	Induction of p53 contributes to apoptosis of HCT-116 human colon cancer cells induced by the dietary compound fisetin.
Author:	Lim, Do Y\|Park, Jung Han Yoon
PMID:	19264955

38.
Journal:	Cancer Sci. 2009 Mar;100(3):503-13.
Title:	Formosanin C-induced apoptosis requires activation of caspase-2 and change of mitochondrial membrane potential.
Author:	Lee, Jenq-Chang\|Su, Chun-Li\|Chen, Lin-Lin\|Won, Shen-Jeu
PMID:	19154411

39.
Journal:	Oncol Rep. 2009 Feb;21(2):351-5.
Title:	Clinical significance of Smac/DIABLO expression in colorectal cancer.
Author:	Endo, Kazuya\|Kohnoe, Shunji\|Watanabe, Akihiro\|Tashiro, Hideya\|Sakata, Hisanobu\|Morita, Masaru\|Kakeji, Yoshihiro\|Maehara, Yoshihiko
PMID:	19148507

40.
Journal:	J Surg Res. 2009 Jan;151(1):163-70. Epub 2007 Dec 3.
Title:	Apoptosis-inducing factor and colon cancer.
Author:	Millan, Alejandro\|Huerta, Sergio
PMID:	18061616

41.
Journal:	Cancer Prev Res (Phila). 2009 Jun;2(6):581-9.
Title:	3,3'-diindolylmethane enhances the efficacy of butyrate in colon cancer prevention through down-regulation of survivin.
Author:	Bhatnagar, Namrata\|Li, Xia\|Chen, Yue\|Zhou, Xudong\|Garrett, Scott H\|Guo, Bin
PMID:	19470789

42.
Journal:	Cell Death Dis. 2010 Jun 3;1:e49.
Title:	XIAP impairs Smac release from the mitochondria during apoptosis.
Author:	Flanagan, L\|Sebastia, J\|Tuffy, L P\|Spring, A\|Lichawska, A\|Devocelle, M\|Prehn, J H M\|Rehm, M
PMID:	21364655

43.
Journal:	Oncol Lett. 2010 Jul;1(4):641-647.
Title:	Predictive value of Smac, VEGF and Ki-67 in rectal cancer treated with neoadjuvant therapy.
Author:	Yan, Hongjiang\|Wang, Renben\|Yu, Jinming\|Jiang, Shumei\|Zhu, Kunli\|Mu, Dianbin\|Xu, Zhongfa
PMID:	22966357

44.
Journal:	Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):20027-32.
Title:	Chemoprevention by nonsteroidal anti-inflammatory drugs eliminates oncogenic intestinal stem cells via SMAC-dependent apoptosis.
Author:	Qiu, Wei\|Wang, Xinwei\|Leibowitz, Brian\|Liu, Hongtao\|Barker, Nick\|Okada, Hitoshi\|Oue, Naohide\|Yasui, Wataru\|Clevers, Hans\|Schoen, Robert E\|Yu, Jian\|Zhang, Lin
PMID:	21041628

45.
Journal:	BMC Gastroenterol. 2010 Aug 22;10:96.
Title:	Fucoidan present in brown algae induces apoptosis of human colon cancer cells.
Author:	Kim, Eun Ji\|Park, So Young\|Lee, Jae-Yong\|Park, Jung Han Yoon
PMID:	20727207

46.
Journal:	Surgery. 2010 Aug;148(2):346-53.
Title:	In vitro and in vivo radiosensitization of colorectal cancer HT-29 cells by the smac mimetic JP-1201.
Author:	Huerta, Sergio\|Gao, Xiaohuan\|Livingston, Edward H\|Kapur, Payal\|Sun, Haizhou\|Anthony, Thomas
PMID:	20633731

47.
Journal:	Surg Today. 2011 Feb;41(2):175-82.
Title:	Inhibitor of apoptosis protein family as diagnostic markers and therapeutic targets of colorectal cancer.
Author:	Miura, Koh\|Fujibuchi, Wataru\|Ishida, Kazuyuki\|Naitoh, Takeshi\|Ogawa, Hitoshi\|Ando, Toshinori\|Yazaki, Nobuki\|Watanabe, Kazuhiro\|Haneda, Sho\|Shibata, Chikashi\|Sasaki, Iwao
PMID:	21264751

48.
Journal:	Biochim Biophys Acta. 2011 May;1813(5):819-26.
Title:	Dimerization of Smac is crucial for its mitochondrial retention by XIAP subsequent to mitochondrial outer membrane permeabilization.
Author:	Flanagan, Lorna\|Sebastia, Jordi\|Delgado, Maria Eugenia\|Lennon, Jennifer C\|Rehm, Markus
PMID:	21354220

49.
Journal:	Mol Cancer Ther. 2011 May;10(5):902-14.
Title:	Therapeutic potential and molecular mechanism of a novel, potent, nonpeptide, Smac mimetic SM-164 in combination with TRAIL for cancer treatment.
Author:	Lu, Jianfeng\|McEachern, Donna\|Sun, Haiying\|Bai, Longchuan\|Peng, Yuefeng\|Qiu, Su\|Miller, Rebecca\|Liao, Jinhui\|Yi, Han\|Liu, Meilan\|Bellail, Anita\|Hao, Chunhai\|Sun, Shi-Yong\|Ting, Adrian T\|Wang, Shaomeng
PMID:	21372226

50.
Journal:	PLoS One. 2011;6(5):e20276.
Title:	Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway.
Author:	Stevenson, Leanne\|Allen, Wendy L\|Proutski, Irina\|Stewart, Gail\|Johnston, Louise\|McCloskey, Karen\|Wilson, Peter M\|Longley, Daniel B\|Johnston, Patrick G
PMID:	21629658

51.
Journal:	J Biol Chem. 2012 Nov 30;287(49):41546-59.
Title:	Systems analysis of cancer cell heterogeneity in caspase-dependent apoptosis subsequent to mitochondrial outer membrane permeabilization.
Author:	Schmid, Jasmin\|Dussmann, Heiko\|Boukes, Gerhardt J\|Flanagan, Lorna\|Lindner, Andreas U\|O'Connor, Carla L\|Rehm, Markus\|Prehn, Jochen H M\|Huber, Heinrich J
PMID:	23038270

52.
Journal:	Int J Clin Exp Pathol. 2012;5(4):290-8. Epub 2011 Apr 30.
Title:	Lentivirus-mediated RNAi knockdown of VEGFA in RKO colorectal cancer cells decreases tumor formation and growth in vitro and in vivo.
Author:	Qiu, Jiang-Feng\|Zhang, Zhi-Qi\|Wang, Yong\|You, Jun
PMID:	22670172

53.
Journal:	Nutr Cancer. 2012;64(4):617-26.
Title:	Ursodeoxycholic acid protects colon cancer HCT116 cells from deoxycholic acid-induced apoptosis by inhibiting apoptosome formation.
Author:	Saeki, Tohru\|Yui, Satoko\|Hirai, Tadashi\|Fujii, Takami\|Okada, Sawami\|Kanamoto, Ryuhei
PMID:	22497644

54.
Journal:	Gut. 2012 May;61(5):725-33.
Title:	Clinical application of a systems model of apoptosis execution for the prediction of colorectal cancer therapy responses and personalisation of therapy.
Author:	Hector, Suzanne\|Rehm, Markus\|Schmid, Jasmin\|Kehoe, Joan\|McCawley, Niamh\|Dicker, Patrick\|Murray, Frank\|McNamara, Deborah\|Kay, Elaine W\|Concannon, Caoimhin G\|Huber, Heinrich J\|Prehn, Jochen H M
PMID:	22082587

55.
Journal:	Br J Nutr. 2012 Jun;107(11):1591-602.
Title:	Stool-fermented Plantago ovata husk induces apoptosis in colorectal cancer cells independently of molecular phenotype.
Author:	Sohn, Vanessa R\|Giros, Anna\|Xicola, Rosa M\|Fluvia, Lourdes\|Grzybowski, Mike\|Anguera, Anna\|Llor, Xavier
PMID:	22018732

56.
Journal:	Med Oncol. 2012 Mar;29(1):168-73.
Title:	Prognostic value of Smac expression in rectal cancer patients treated with neoadjuvant therapy.
Author:	Yan, Hongjiang\|Yu, Jinming\|Wang, Renben\|Jiang, Shumei\|Zhu, Kunli\|Mu, Dianbin\|Xu, Zhongfa
PMID:	21264534

57.
Journal:	Br J Cancer. 2012 Apr 24;106(9):1499-1505.
Title:	Apoptosome-dependent caspase activation proteins as prognostic markers in Stage II and III colorectal cancer.
Author:	Hector, S\|Conlon, S\|Schmid, J\|Dicker, P\|Cummins, R J\|Concannon, C G\|Johnston, P G\|Kay, E W\|Prehn, J H M
PMID:	22481083

58.
Journal:	Oncogene. 2013 May 9;32(19):2380-9.
Title:	An apoptosis-independent role of SMAC in tumor suppression.
Author:	Qiu, W\|Liu, H\|Sebastini, A\|Sun, Q\|Wang, H\|Zhang, L\|Yu, J
PMID:	22751125

59.
Journal:	Clin Cancer Res. 2013 Jul 15;19(14):3914-24.
Title:	Temporal and spatial evolution of therapy-induced tumor apoptosis detected by caspase-3-selective molecular imaging.
Author:	Nguyen, Quang-De\|Lavdas, Ioannis\|Gubbins, James\|Smith, Graham\|Fortt, Robin\|Carroll, Laurence S\|Graham, Martin A\|Aboagye, Eric O
PMID:	23729364

60.
Journal:	BMC Cancer. 2014 Jan 15;14:24.
Title:	Ceramide targets xIAP and cIAP1 to sensitize metastatic colon and breast cancer cells to apoptosis induction to suppress tumor progression.
Author:	Paschall, Amy V\|Zimmerman, Mary A\|Torres, Christina M\|Yang, Dafeng\|Chen, May R\|Li, Xia\|Bieberich, Erhard\|Bai, Aiping\|Bielawski, Jacek\|Bielawska, Alicja\|Liu, Kebin
PMID:	24422988

61.
Journal:	Clin Cancer Res. 2014 Jul 15;20(14):3809-17.
Title:	CLIC4, ERp29, and Smac/DIABLO derived from metastatic cancer stem-like cells stratify prognostic risks of colorectal cancer.
Author:	Deng, Yong-Jian\|Tang, Na\|Liu, Chao\|Zhang, Jiang-Yu\|An, Sheng-Li\|Peng, Yin-Li\|Ma, Li-Li\|Li, Guang-Qiu\|Jiang, Qiang\|Hu, Chun-Ting\|Wang, Ya-Nan\|Liang, Yao-Ze\|Bian, Xiu-Wu\|Fang, Wei-Gang\|Ding, Yan-Qing
PMID:	24916695

62.
Journal:	PLoS One. 2014 Sep 8;9(9):e107165.
Title:	EGFR-targeted TRAIL and a Smac mimetic synergize to overcome apoptosis resistance in KRAS mutant colorectal cancer cells.
Author:	Moller, Yvonne\|Siegemund, Martin\|Beyes, Sven\|Herr, Ricarda\|Lecis, Daniele\|Delia, Domenico\|Kontermann, Roland\|Brummer, Tilman\|Pfizenmaier, Klaus\|Olayioye, Monilola A
PMID:	25198428

63.
Journal:	Oncol Lett. 2014 Dec;8(6):2581-2586.
Title:	Smac/DIABLO expression in human gastrointestinal carcinoma: Association with clinicopathological parameters and survivin expression.
Author:	Shintani, Michiko\|Sangawa, Akiko\|Yamao, Naoki\|Kamoshida, Shingo
PMID:	25364431

64.
Journal:	Radiat Oncol. 2015 Jun 13;10:131.
Title:	High levels of X-linked Inhibitor-of-Apoptosis Protein (XIAP) are indicative of radio chemotherapy resistance in rectal cancer.
Author:	Flanagan, L\|Kehoe, J\|Fay, J\|Bacon, O\|Lindner, A U\|Kay, E W\|Deasy, J\|McNamara, D A\|Prehn, J H M
PMID:	26071313

65.
Journal:	Radiat Oncol. 2015 Sep 17;10:198.
Title:	The SMAC mimetic BV6 sensitizes colorectal cancer cells to ionizing radiation by interfering with DNA repair processes and enhancing apoptosis.
Author:	Hehlgans, Stephanie\|Oppermann, Julius\|Reichert, Sebastian\|Fulda, Simone\|Rodel, Claus\|Rodel, Franz
PMID:	26383618

66.
Journal:	Mol Cancer Ther. 2015 Nov;14(11):2569-75.
Title:	A Phase I Study of the SMAC-Mimetic Birinapant in Adults with Refractory Solid Tumors or Lymphoma.
Author:	Amaravadi, Ravi K\|Schilder, Russell J\|Martin, Lainie P\|Levin, Myron\|Graham, Martin A\|Weng, David E\|Adjei, Alex A
PMID:	26333381

67.
Journal:	Biomaterials. 2015 Dec;71:84-99.
Title:	LNA aptamer based multi-modal, Fe3O4-saturated lactoferrin (Fe3O4-bLf) nanocarriers for triple positive (EpCAM, CD133, CD44) colon tumor targeting and NIR, MRI and CT imaging.
Author:	Roy, Kislay\|Kanwar, Rupinder K\|Kanwar, Jagat R
PMID:	26318819

68.
Journal:	Cell Death Differ. 2015 Sep;22(9):1463-76.
Title:	USP11-dependent selective cIAP2 deubiquitylation and stabilization determine sensitivity to Smac mimetics.
Author:	Lee, E-W\|Seong, D\|Seo, J\|Jeong, M\|Lee, H-K\|Song, J
PMID:	25613375

69.
Journal:	Tumour Biol. 2015 May;36(5):3775-89.
Title:	Antimicrobial peptide m2163 or m2386 identified from Lactobacillus casei ATCC 334 can trigger apoptosis in the human colorectal cancer cell line SW480.
Author:	Tsai, Tsung-Lin\|Li, An-Chieh\|Chen, Yi-Chieh\|Liao, Yi-Shun\|Lin, Thy-Hou
PMID:	25557887

70.
Journal:	Oncotarget. 2016 Jan 26;7(4):3709-25.
Title:	Cooperative TRAIL production mediates IFNalpha/Smac mimetic-induced cell death in TNFalpha-resistant solid cancer cells.
Author:	Roesler, Stefanie\|Eckhardt, Ines\|Wolf, Sebastian\|Fulda, Simone
PMID:	26788912

71.
Journal:	Mol Med Rep. 2016 Mar;13(3):2661-70.
Title:	Effects of autophagy regulation of tumor-associated macrophages on radiosensitivity of colorectal cancer cells.
Author:	Shao, Le-Ning\|Zhu, Bao-Song\|Xing, Chun-Gen\|Yang, Xiao-Dong\|Young, Wu\|Cao, Jian-Ping
PMID:	26821367

72.
Journal:	PLoS One. 2016 Feb 9;11(2):e0148775.
Title:	Flavokawain C Inhibits Cell Cycle and Promotes Apoptosis, Associated with Endoplasmic Reticulum Stress and Regulation of MAPKs and Akt Signaling Pathways in HCT 116 Human Colon Carcinoma Cells.
Author:	Phang, Chung-Weng\|Karsani, Saiful Anuar\|Sethi, Gautam\|Abd Malek, Sri Nurestri
PMID:	26859847

73.
Journal:	Oncotarget. 2016 Jul 5;7(27):41488-41504.
Title:	Hypoxia regulates TRAIL sensitivity of colorectal cancer cells through mitochondrial autophagy.
Author:	Knoll, Gertrud\|Bittner, Sebastian\|Kurz, Maria\|Jantsch, Jonathan\|Ehrenschwender, Martin
PMID:	27166192

74.
Journal:	BMC Cancer. 2016 Aug 12;16:624.
Title:	IAP antagonists Birinapant and AT-406 efficiently synergise with either TRAIL, BRAF, or BCL-2 inhibitors to sensitise BRAFV600E colorectal tumour cells to apoptosis.
Author:	Perimenis, Philippos\|Galaris, Apostolos\|Voulgari, Alexandra\|Prassa, Margarita\|Pintzas, Alexander
PMID:	27520705

75.
Journal:	BMC Complement Altern Med. 2016 Oct 1;16(1):384.
Title:	Methylferulate from Tamarix aucheriana inhibits growth and enhances chemosensitivity of human colorectal cancer cells: possible mechanism of action.
Author:	Abaza, Mohamed Salah I\|Afzal, Mohammad\|Al-Attiyah, Raja'a J\|Guleri, Radhika
PMID:	27716288

76.
Journal:	Gastroenterology. 2017 Mar;152(4):867-879.
Title:	Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor-Mediated Destruction of Intestinal Epithelial Cells.
Author:	Grabinger, Thomas\|Bode, Konstantin J\|Demgenski, Janine\|Seitz, Carina\|Delgado, M Eugenia\|Kostadinova, Feodora\|Reinhold, Cindy\|Etemadi, Nima\|Wilhelm, Sabine\|Schweinlin, Matthias\|Hanggi, Kay\|Knop, Janin\|Hauck, Christof\|Walles, Heike\|Silke, John\|Wajant, Haral
PMID:	27889570

77.
Journal:	J Exp Med. 2017 Jun 5;214(6):1655-1662.
Title:	Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice.
Author:	He, Gui-Wei\|Gunther, Claudia\|Thonn, Veronika\|Yu, Yu-Qiang\|Martini, Eva\|Buchen, Barbara\|Neurath, Markus F\|Sturzl, Michael\|Becker, Christoph
PMID:	28476895

78.
Journal:	J Drug Target. 2018 Jan;26(1):45-54.
Title:	Cationic liposome co-encapsulation of SMAC mimetic and zVAD using a novel lipid bilayer fusion loaded with MLKL-pDNA for tumour inhibition in vivo.
Author:	Sun, Dan\|Zhao, Linshu\|Lin, Junzhong\|Zhao, Yun\|Zheng, Yu
PMID:	28649853