Primary Site >> Colorectal Cancer

Gene >> DHODH

Journal: Biochem Pharmacol. 1990 Jan 1;39(1):135-44.
Title: Retention of in vivo antipyrimidine effects of Brequinar sodium (DUP-785; NSC 368390) in murine liver, bone marrow and colon cancer.
Author: Peters, G J|Nadal, J C|Laurensse, E J|de Kant, E|Pinedo, H M
PMID: 2153375
Journal: Free Radic Biol Med. 2010 Jul 1;49(1):109-16.
Title: Dihydroorotate dehydrogenase is required for N-(4-hydroxyphenyl)retinamide-induced reactive oxygen species production and apoptosis.
Author: Hail, Numsen Jr|Chen, Ping|Kepa, Jadwiga J|Bushman, Lane R|Shearn, Colin
PMID: 20399851
Journal: Acta Naturae. 2014 Jan;6(1):69-75.
Title: The Role of Dihydroorotate Dehydrogenase in Apoptosis Induction in Response to Inhibition of the Mitochondrial Respiratory Chain Complex III.
Author: Khutornenko, A A|Dalina, A A|Chernyak, B V|Chumakov, P M|Evstafieva, A G
PMID: 24772329
Journal: Biochimie. 2017 Apr;135:154-163.
Title: Dihydroorotate dehydrogenase (DHODH) inhibitors affect ATP depletion, endogenous ROS and mediate S-phase arrest in breast cancer cells.
Author: Mohamad Fairus, A K|Choudhary, B|Hosahalli, S|Kavitha, N|Shatrah, O
PMID: 28196676