Literatures

Primary Site >> Colorectal Cancer

Gene >> DHFR

1.
Journal:	J Biol Chem. 1989 Feb 25;264(6):3524-8.
Title:	Amplification of a polymorphic dihydrofolate reductase gene expressing an enzyme with decreased binding to methotrexate in a human colon carcinoma cell line, HCT-8R4, resistant to this drug.
Author:	Srimatkandada, S\|Schweitzer, B I\|Moroson, B A\|Dube, S\|Bertino, J R
PMID:	2914962

2.
Journal:	Biotechniques. 1989 Sep;7(8):830-8.
Title:	Sequence analysis of a human gene responsible for drug resistance: a rapid method for manual and automated direct sequencing of products generated by the polymerase chain reaction.
Author:	Dicker, A P\|Volkenandt, M\|Adamo, A\|Barreda, C\|Bertino, J R
PMID:	2698661

3.
Journal:	Jpn J Cancer Res. 1993 Jan;84(1):9-12.
Title:	Differential alterations of dihydrofolate reductase gene in human leukemia cell lines made resistant to various folate analogues.
Author:	Miyachi, H\|Takemura, Y\|Kobayashi, H\|Ando, K\|Ando, Y
PMID:	8449831

4.
Journal:	Br J Cancer. 1994 Dec;70(6):1075-84.
Title:	Determinants of trimetrexate lethality in human colon cancer cells.
Author:	Grem, J L\|Voeller, D M\|Geoffroy, F\|Horak, E\|Johnston, P G\|Allegra, C J
PMID:	7981057

5.
Journal:	Arkh Patol. 1995 Sep-Oct;57(5):34-8.
Title:	[Stimulation of differentiation of LIM 1215 large intestinal tumor cells during expression of the p53 exogenous antioncogene or the activated ras oncogene].
Author:	Raikhlin, N T\|Volodina, Iu L\|Smirnova, E A\|Perevoshchikov, A G\|Chumakov, P M\|Kopnin, B P
PMID:	8579493

6.
Journal:	Invest New Drugs. 1996;14(3):305-16.
Title:	Tomudex (ZD1694): from concept to care, a programme in rational drug discovery.
Author:	Jackman, A L\|Boyle, F T\|Harrap, K R
PMID:	8958186

7.
Journal:	Proc Natl Acad Sci U S A. 1997 Sep 16;94(19):10144-9.
Title:	DHFR/MSH3 amplification in methotrexate-resistant cells alters the hMutSalpha/hMutSbeta ratio and reduces the efficiency of base-base mismatch repair.
Author:	Drummond, J T\|Genschel, J\|Wolf, E\|Modrich, P
PMID:	9294177

8.
Journal:	Int J Cancer. 1998 May 4;76(3):383-92.
Title:	Resistance to high concentrations of methotrexate and 5-fluorouracil of differentiated HT-29 colon-cancer cells is restricted to cells of enterocytic phenotype.
Author:	Lesuffleur, T\|Violette, S\|Vasile-Pandrea, I\|Dussaulx, E\|Barbat, A\|Muleris, M\|Zweibaum, A
PMID:	9579576

9.
Journal:	J Med Chem. 1998 Dec 17;41(26):5310-9.
Title:	Synthesis and potent antifolate activity and cytotoxicity of B-ring deaza analogues of the nonpolyglutamatable dihydrofolate reductase inhibitor Nalpha-(4-amino-4-deoxypteroyl)-Ndelta-hemiphthaloyl- L-ornithine (PT523).
Author:	Rosowsky, A\|Wright, J E\|Vaidya, C M\|Bader, H\|Forsch, R A\|Mota, C E\|Pardo, J\|Chen, C S\|Chen, Y N
PMID:	9857098

10.
Journal:	Cancer Chemother Pharmacol. 1999;44(5):372-80.
Title:	A phase I evaluation of multitargeted antifolate (MTA, LY231514), administered every 21 days, utilizing the modified continual reassessment method for dose escalation.
Author:	Rinaldi, D A\|Kuhn, J G\|Burris, H A\|Dorr, F A\|Rodriguez, G\|Eckhardt, S G\|Jones, S\|Woodworth, J R\|Baker, S\|Langley, C\|Mascorro, D\|Abrahams, T\|Von Hoff, D D
PMID:	10501910

11.
Journal:	Int J Cancer. 2000 Sep 15;87(6):771-8.
Title:	Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates.
Author:	Backus, H H\|Pinedo, H M\|Wouters, D\|Padron, J M\|Molders, N\|van Der Wilt, C L\|van Groeningen, C J\|Jansen, G\|Peters, G J
PMID:	10956384

12.
Journal:	Anticancer Drug Des. 2001 Apr-Jun;16(2-3):119-28.
Title:	Investigations on the biological properties of the lipophilic DHFR-inhibitory benzoprims reveal non-folate modes of action and opportunities for anti-cancer drug design.
Author:	Croughton, K A\|Matthews, C S\|Griffin, R J\|Stevens, M F
PMID:	11962509

13.
Journal:	Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):3400-5. Epub 2002 Mar 12.
Title:	Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: a method to modulate gene expression.
Author:	Mayer-Kuckuk, Philipp\|Banerjee, Debabrata\|Malhotra, Sundeep\|Doubrovin, Mikhail\|Iwamoto, Marian\|Akhurst, Tim\|Balatoni, Julius\|Bornmann, William\|Finn, Ronald\|Larson, Steven\|Fong, Yuman\|Gelovani Tjuvajev, Juri\|Blasberg, Ronald\|Bertino, Joseph R
PMID:	11891321

14.
Journal:	Biochim Biophys Acta. 2002 Jul 18;1587(2-3):164-73.
Title:	Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase.
Author:	Banerjee, Debabrata\|Mayer-Kuckuk, Philipp\|Capiaux, Gina\|Budak-Alpdogan, Tulin\|Gorlick, Richard\|Bertino, Joseph R
PMID:	12084458

15.
Journal:	Hum Gene Ther. 2003 Mar 20;14(5):435-46.
Title:	Retroviral transduction of a mutant dihydrofolate reductase-thymidylate synthase fusion gene into murine marrow cells confers resistance to both methotrexate and 5-fluorouracil.
Author:	Capiaux, Gina M\|Budak-Alpdogan, Tulin\|Takebe, Naoko\|Mayer-Kuckuk, Philipp\|Banerjee, Debabrata\|Maley, Frank\|Bertino, Joseph R
PMID:	12691609

16.
Journal:	Curr Pharm Des. 2003;9(31):2593-613.
Title:	Anticancer antifolates: current status and future directions.
Author:	McGuire, John J
PMID:	14529544

17.
Journal:	Mol Cancer Ther. 2003 Jun;2(6):535-41.
Title:	mRNA expression levels of E2F transcription factors correlate with dihydrofolate reductase, reduced folate carrier, and thymidylate synthase mRNA expression in osteosarcoma.
Author:	Sowers, Rebecca\|Toguchida, Junya\|Qin, Jing\|Meyers, Paul A\|Healey, John H\|Huvos, Andrew\|Banerjee, Debabrata\|Bertino, Joseph R\|Gorlick, Richard
PMID:	12813132

18.
Journal:	Eur J Nucl Med Mol Imaging. 2003 Sep;30(9):1281-91. Epub 2003 Mar 27.
Title:	Imaging of dihydrofolate reductase fusion gene expression in xenografts of human liver metastases of colorectal cancer in living rats.
Author:	Mayer-Kuckuk, Philipp\|Doubrovin, Mikhail\|Gusani, Niraj J\|Gade, Terence\|Balatoni, Julius\|Akhurst, Tim\|Finn, Ronald\|Fong, Yuman\|Koutcher, Jason A\|Larson, Steven\|Blasberg, Ronald\|Tjuvajev, Juri Gelovani\|Bertino, Joseph R\|Banerjee, Debabrata
PMID:	12664136

19.
Journal:	Biochem J. 2004 Mar 15;378(Pt 3):999-1006.
Title:	Characterization of a cis-acting regulatory element in the protein-coding region of human dihydrofolate reductase mRNA.
Author:	Tai, Ningwen\|Schmitz, John C\|Chen, Tian-min\|Chu, Edward
PMID:	14664697

20.
Journal:	Clin Cancer Res. 2005 Apr 1;11(7):2612-9.
Title:	Variance in the expression of 5-Fluorouracil pathway genes in colorectal cancer.
Author:	Kidd, Elizabeth A\|Yu, Jinsheng\|Li, Xia\|Shannon, William D\|Watson, Mark A\|McLeod, Howard L
PMID:	15814641

21.
Journal:	Oncogene. 2005 Oct 13;24(45):6842-7.
Title:	Genetic determinants of methotrexate responsiveness and resistance in colon cancer cells.
Author:	Morales, Cristina\|Ribas, Maria\|Aiza, Gemma\|Peinado, Miguel A
PMID:	16007155

22.
Journal:	Cancer Lett. 2006 Oct 28;242(2):168-79.
Title:	Tumor quantification of several fluoropyrimidines resistance gene expression with a unique quantitative RT-PCR method. Implications for pretherapeutic determination of tumor resistance phenotype.
Author:	Barbado, Maud\|Preisser, Laurence\|Boisdron-Celle, Michele\|Verriele, Veronique\|Lorimier, Gerard\|Gamelin, Erick\|Morel, Alain
PMID:	16387426

23.
Journal:	Carcinogenesis. 2007 Aug;28(8):1672-9. Epub 2007 Apr 21.
Title:	Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet.
Author:	Curtin, Karen\|Slattery, Martha L\|Ulrich, Cornelia M\|Bigler, Jeannette\|Levin, Theodore R\|Wolff, Roger K\|Albertsen, Hans\|Potter, John D\|Samowitz, Wade S
PMID:	17449906

24.
Journal:	Int J Biochem Cell Biol. 2007;39(12):2215-25.
Title:	Effects of folate cycle disruption by the green tea polyphenol epigallocatechin-3-gallate.
Author:	Navarro-Peran, Enma\|Cabezas-Herrera, Juan\|Campo, Luis Sanchez Del\|Rodriguez-Lopez, Jose Neptuno
PMID:	17683969

25.
Journal:	Acta Oncol. 2008;47(6):1054-61.
Title:	Prognostic significance of numeric aberrations of genes for thymidylate synthase, thymidine phosphorylase and dihydrofolate reductase in colorectal cancer.
Author:	Jensen, Soren Astrup\|Vainer, Ben\|Witton, Caroline Janet\|Jorgensen, Jan Trost\|Sorensen, Jens Benn
PMID:	18607850

26.
Journal:	BMC Med Genomics. 2008 Aug 11;1:35.
Title:	Role of caveolin 1, E-cadherin, Enolase 2 and PKCalpha on resistance to methotrexate in human HT29 colon cancer cells.
Author:	Selga, Elisabet\|Morales, Cristina\|Noe, Veronique\|Peinado, Miguel A\|Ciudad, Carlos J
PMID:	18694510

27.
Journal:	Clin Cancer Res. 2008 Dec 15;14(24):8080-6.
Title:	miR-192 Regulates dihydrofolate reductase and cellular proliferation through the p53-microRNA circuit.
Author:	Song, Bo\|Wang, Yuan\|Kudo, Kenji\|Gavin, Elaine J\|Xi, Yaguang\|Ju, Jingfang
PMID:	19088023

28.
Journal:	Mol Cancer Ther. 2009 Feb;8(2):424-32.
Title:	Dihydrofolate reductase amplification and sensitization to methotrexate of methotrexate-resistant colon cancer cells.
Author:	Morales, Cristina\|Garcia, Maria J\|Ribas, Maria\|Miro, Rosa\|Munoz, Mar\|Caldas, Carlos\|Peinado, Miguel A
PMID:	19190117

29.
Journal:	EMBO Mol Med. 2009 Sep;1(6-7):323-37.
Title:	Methotrexate induces oxidative DNA damage and is selectively lethal to tumour cells with defects in the DNA mismatch repair gene MSH2.
Author:	Martin, Sarah A\|McCarthy, Afshan\|Barber, Louise J\|Burgess, Darren J\|Parry, Suzanne\|Lord, Christopher J\|Ashworth, Alan
PMID:	20049736

30.
Journal:	PLoS One. 2009 Dec 24;4(12):e8445.
Title:	MiR-24 tumor suppressor activity is regulated independent of p53 and through a target site polymorphism.
Author:	Mishra, Prasun J\|Song, Bo\|Mishra, Pravin J\|Wang, Yuan\|Humeniuk, Rita\|Banerjee, Debabrata\|Merlino, Glenn\|Ju, Jingfang\|Bertino, Joseph R
PMID:	20041160

31.
Journal:	J Transl Med. 2009 Jan 20;7:8.
Title:	TRIP-Br2 promotes oncogenesis in nude mice and is frequently overexpressed in multiple human tumors.
Author:	Cheong, Jit Kong\|Gunaratnam, Lakshman\|Zang, Zhi Jiang\|Yang, Christopher M\|Sun, Xiaoming\|Nasr, Susan L\|Sim, Khe Guan\|Peh, Bee Keow\|Rashid, Suhaimi Bin Abdul\|Bonventre, Joseph V\|Salto-Tellez, Manuel\|Hsu, Stephen I
PMID:	19152710

32.
Journal:	Hum Gene Ther. 2009 Jul;20(7):728-38.
Title:	Antitumor therapy based on cellular competition.
Author:	Martinez-Quintanilla, Jordi\|Cascallo, Manel\|Fillat, Cristina\|Alemany, Ramon
PMID:	19281300

33.
Journal:	Cancer Chemother Pharmacol. 2010 Aug;66(3):547-58.
Title:	Cellular and molecular mechanisms for the synergistic cytotoxicity elicited by oxaliplatin and pemetrexed in colon cancer cell lines.
Author:	Nannizzi, Sara\|Veal, Gareth J\|Giovannetti, Elisa\|Mey, Valentina\|Ricciardi, Simona\|Ottley, Christopher J\|Del Tacca, Mario\|Danesi, Romano
PMID:	20020129

34.
Journal:	Mol Cancer. 2010 Apr 30;9:96.
Title:	Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells.
Author:	Song, Bo\|Wang, Yuan\|Titmus, Matthew A\|Botchkina, Galina\|Formentini, Andrea\|Kornmann, Marko\|Ju, Jingfang
PMID:	20433742

35.
Journal:	Cancer Epidemiol Biomarkers Prev. 2010 Jul;19(7):1812-21.
Title:	A candidate gene study of folate-associated one carbon metabolism genes and colorectal cancer risk.
Author:	Levine, A Joan\|Figueiredo, Jane C\|Lee, Won\|Conti, David V\|Kennedy, Kathleen\|Duggan, David J\|Poynter, Jenny N\|Campbell, Peter T\|Newcomb, Polly\|Martinez, Maria Elena\|Hopper, John L\|Le Marchand, Loic\|Baron, John A\|Limburg, Paul J\|Ulrich, Cornelia M\|Haile, Ro
PMID:	20615890

36.
Journal:	DNA Cell Biol. 2011 Oct;30(10):771-6.
Title:	Association of MTHFR, MTR, MTRR, RFC1, and DHFR gene polymorphisms with susceptibility to sporadic colon cancer.
Author:	Jokic, Mladen\|Brcic-Kostic, Krunoslav\|Stefulj, Jasminka\|Catela Ivkovic, Tina\|Bozo, Loncar\|Gamulin, Marija\|Kapitanovic, Sanja
PMID:	21438757

37.
Journal:	Pharmacogenet Genomics. 2012 Apr;22(4):290-304.
Title:	Functional polymorphisms of folate metabolism and response to chemotherapy for colorectal cancer, a systematic review and meta-analysis.
Author:	Jennings, Barbara Anne\|Kwok, Chun Shing\|Willis, Gavin\|Matthews, Victoria\|Wawruch, Pawel\|Loke, Yoon Kong
PMID:	22388795

38.
Journal:	Mol Nutr Food Res. 2013 Apr;57(4):721-34.
Title:	Gene-diet-interactions in folate-mediated one-carbon metabolism modify colon cancer risk.
Author:	Liu, Amy Y\|Scherer, Dominique\|Poole, Elizabeth\|Potter, John D\|Curtin, Karen\|Makar, Karen\|Slattery, Martha L\|Caan, Bette J\|Ulrich, Cornelia M
PMID:	22961839

39.
Journal:	J Oncol. 2013;2013:386906.
Title:	Analysis of the mRNA expression of chemotherapy-related genes in colorectal carcinoma using the danenberg tumor profile method.
Author:	Sasaki, Shin\|Watanabe, Toshiyuki\|Nakayama, Hiroshi
PMID:	23577026

40.
Journal:	Int J Mol Sci. 2015 Dec 1;16(12):28486-97.
Title:	Simultaneous Analysis of SEPT9 Promoter Methylation Status, Micronuclei Frequency, and Folate-Related Gene Polymorphisms: The Potential for a Novel Blood-Based Colorectal Cancer Biomarker.
Author:	Ravegnini, Gloria\|Zolezzi Moraga, Juan Manuel\|Maffei, Francesca\|Musti, Muriel\|Zenesini, Corrado\|Simeon, Vittorio\|Sammarini, Giulia\|Festi, Davide\|Hrelia, Patrizia\|Angelini, Sabrina
PMID:	26633373

41.
Journal:	J Nutr Sci Vitaminol (Tokyo). 2015;61(6):455-9.
Title:	Gene-Nutrient Interaction between Folate and Dihydrofolate Reductase in Risk for Adenomatous Polyp Occurrence: A Preliminary Report.
Author:	Choi, Jeong-hwa\|Yates, Zoe\|Martin, Charlotte\|Boyd, Lyndell\|Ng, Xiaowei\|Skinner, Virginia\|Wai, Ron\|Veysey, Martin\|Lucock, Mark
PMID:	26875486

42.
Journal:	BBA Clin. 2015 Jul 7;4:45-51.
Title:	Folate status, folate-related genes and serum miR-21 expression: Implications for miR-21 as a biomarker.
Author:	Beckett, Emma Louise\|Martin, Charlotte\|Choi, Jeong Hwa\|King, Katrina\|Niblett, Suzanne\|Boyd, Lyndell\|Duesing, Konsta\|Yates, Zoe\|Veysey, Martin\|Lucock, Mark
PMID:	26674922

43.
Journal:	Cancer. 2015 Oct 15;121(20):3684-91.
Title:	Folate-mediated one-carbon metabolism genes and interactions with nutritional factors on colorectal cancer risk: Women's Health Initiative Observational Study.
Author:	Cheng, Ting-Yuan David\|Makar, Karen W\|Neuhouser, Marian L\|Miller, Joshua W\|Song, Xiaoling\|Brown, Elissa C\|Beresford, Shirley A A\|Zheng, Yingye\|Poole, Elizabeth M\|Galbraith, Rachel L\|Duggan, David J\|Habermann, Nina\|Bailey, Lynn B\|Maneval, David R\|Caudill,
PMID:	26108676

44.
Journal:	Spectrochim Acta A Mol Biomol Spectrosc. 2015 Jun 15;145:425-439.
Title:	Synthesis, spectroscopic properties, molecular docking, anti-colon cancer and anti-microbial studies of some novel metal complexes for 2-amino-4-phenylthiazole derivative.
Author:	Al-Harbi, Sami A\|Bashandy, Mahmoud S\|Al-Saidi, Hammed M\|Emara, Adel A A\|Mousa, Tarek A A
PMID:	25796013

45.
Journal:	J Med Genet. 2015 Feb;52(2):135-44.
Title:	Novel role for non-homologous end joining in the formation of double minutes in methotrexate-resistant colon cancer cells.
Author:	Meng, Xiangning\|Qi, Xiuying\|Guo, Huanhuan\|Cai, Mengdi\|Li, Chunxiang\|Zhu, Jing\|Chen, Feng\|Guo, Huan\|Li, Jie\|Zhao, Yuzhen\|Liu, Peng\|Jia, Xueyuan\|Yu, Jingcui\|Zhang, Chunyu\|Sun, Wenjing\|Yu, Yang\|Jin, Yan\|Bai, Jing\|Wang, Mingrong\|Rosales, Jesusa\|Lee, Ki-Young\|
PMID:	25537274

46.
Journal:	Eur J Pharm Sci. 2015 Jan 23;66:59-69.
Title:	A novel antibiotic-delivery system by using ovotransferrin as targeting molecule.
Author:	Ibrahim, Hisham R\|Tatsumoto, Sayuri\|Ono, Hajime\|Van Immerseel, Filip\|Raspoet, Ruth\|Miyata, Takeshi
PMID:	25315410

47.
Journal:	Int J Mol Med. 2016 Feb;37(2):319-28.
Title:	Association between mRNA expression of chemotherapy-related genes and clinicopathological features in colorectal cancer: A large-scale population analysis.
Author:	Shimamoto, Yuji\|Nukatsuka, Mamoru\|Takechi, Teiji\|Fukushima, Masakazu
PMID:	26676887

48.
Journal:	PLoS One. 2016 Sep 29;11(9):e0163961.
Title:	Folic Acid-Metabolizing Enzymes Regulate the Antitumor Effect of 5-Fluoro-2'-Deoxyuridine in Colorectal Cancer Cell Lines.
Author:	Tsukihara, Hiroshi\|Tsunekuni, Kenta\|Takechi, Teiji
PMID:	27685866

49.
Journal:	J Biomol Struct Dyn. 2017 May;35(7):1474-1490.
Title:	Human dihydrofolate reductase and thymidylate synthase form a complex in vitro and co-localize in normal and cancer cells.
Author:	Antosiewicz, Anna\|Jarmula, Adam\|Przybylska, Dorota\|Mosieniak, Grazyna\|Szczepanowska, Joanna\|Kowalkowska, Anna\|Rode, Wojciech\|Ciesla, Joanna
PMID:	27187663

50.
Journal:	PLoS One. 2017 Oct 2;12(10):e0185792.
Title:	One-carbon genetic variants and the role of MTHFD1 1958G>A in liver and colon cancer risk according to global DNA methylation.
Author:	Moruzzi, Sara\|Guarini, Patrizia\|Udali, Silvia\|Ruzzenente, Andrea\|Guglielmi, Alfredo\|Conci, Simone\|Pattini, Patrizia\|Martinelli, Nicola\|Olivieri, Oliviero\|Tammen, Stephanie A\|Choi, Sang-Woon\|Friso, Simonetta
PMID:	28968444

51.
Journal:	J Pers Med. 2018 Feb 16;8(1). pii: jpm8010010.
Title:	Gene Environment Interactions and Predictors of Colorectal Cancer in Family-Based, Multi-Ethnic Groups.
Author:	Shiao, S Pamela K\|Grayson, James\|Yu, Chong Ho\|Wasek, Brandi\|Bottiglieri, Teodoro
PMID:	29462916

52.
Journal:	Cancer Chemother Pharmacol. 2018 Aug;82(2):237-243.
Title:	The association of polymorphisms in folate-metabolizing genes with response to adjuvant chemotherapy of colorectal cancer.
Author:	Yousef, Al-Motassem\|Zawiah, Mohammed\|Al-Yacoub, Shorouq\|Kadi, Taha\|Tantawi, Dua' A\|Al-Ramadhani, Hanguin
PMID:	29845393

53.
Journal:	Nutrients. 2018 Jun 20;10(6). pii: nu10060795.
Title:	Personalized Nutrition-Genes, Diet, and Related Interactive Parameters as Predictors of Cancer in Multiethnic Colorectal Cancer Families.
Author:	Shiao, S Pamela K\|Grayson, James\|Lie, Amanda\|Yu, Chong Ho
PMID:	29925788

54.
Journal:	J Pers Med. 2018 Aug 6;8(3). pii: jpm8030026.
Title:	Gene-Metabolite Interaction in the One Carbon Metabolism Pathway: Predictors of Colorectal Cancer in Multi-Ethnic Families.
Author:	Shiao, S Pamela K\|Grayson, James\|Yu, Chong Ho
PMID:	30082654

55.
Journal:	Drug Metab Pers Ther. 2018 Sep 12.
Title:	Early disease relapse in a patient with colorectal cancer who harbors genetic variants of DPYD, TYMS, MTHFR and DHFR after treatment with 5-fluorouracil-based chemotherapy.
Author:	Zawiah, Mohammed\|Yousef, Al-Motassem\|Kadi, Taha\|Yousef, Mohammed\|Majdalawi, Khalil\|Al-Yacoub, Shorouq\|Al-Hiary, Rasha\|Tantawi, Dua'a\|Mukred, Ramzi\|Ajaj, Abdel Rahman
PMID:	30207288

56.
Journal:	Mini Rev Med Chem. 2018 Oct 17. pii: MRMC-EPUB-93769.
Title:	Synthesis, cytotoxicity, antimicrobial and docking simulation of novel pyrazolo[3,4-d]pyrimidine and pyrazolo[4,3-e][1,2,4]triazolo[3,4-c]pyrimidine derivatives.
Author:	Hassaneen, Hamdi M\|Saleh, Fatma M\|Abdallah, Tayseer A\|Mohamed, Magda F\|Mohamed, Yasmin Sh\|Awad, Enas M\|Abdelhamid, Ismail A
PMID:	30332953