Primary Site >> Pancreatic Cancer
Gene >> DCLK1
| 1. | |||||||||||
| Journal: | Cancer Biol Ther. 2012 Aug;13(10):871-9. | ||||||||||
| Title: | Exome sequencing and digital PCR analyses reveal novel mutated genes related to the metastasis of pancreatic ductal adenocarcinoma. | ||||||||||
| Author: | Zhou, Bin|Irwanto, Astrid|Guo, Yun-Miao|Bei, Jin-Xin|Wu, Qiao|Chen, Ge|Zhang, Tai-Ping|Lei, Jin-Jv|Feng, Qi-Sheng|Chen, Li-Zhen|Liu, Jianjun|Zhao, Yu-Pei | ||||||||||
| PMID: | 22797009 | ||||||||||
| 2. | |||||||||||
| Journal: | PLoS One. 2013 Sep 9;8(9):e73940. | ||||||||||
| Title: | DCLK1 regulates pluripotency and angiogenic factors via microRNA-dependent mechanisms in pancreatic cancer. | ||||||||||
| Author: | Sureban, Sripathi M|May, Randal|Qu, Dongfeng|Weygant, Nathaniel|Chandrakesan, Parthasarathy|Ali, Naushad|Lightfoot, Stan A|Pantazis, Panayotis|Rao, Chinthalapally V|Postier, Russell G|Houchen, Courtney W | ||||||||||
| PMID: | 24040120 | ||||||||||
| 3. | |||||||||||
| Journal: | Gastroenterology. 2014 Jan;146(1):245-56. | ||||||||||
| Title: | DCLK1 marks a morphologically distinct subpopulation of cells with stem cell properties in preinvasive pancreatic cancer. | ||||||||||
| Author: | Bailey, Jennifer M|Alsina, Janivette|Rasheed, Zeshaan A|McAllister, Florencia M|Fu, Ya-Yuan|Plentz, Ruben|Zhang, Hao|Pasricha, Pankaj J|Bardeesy, Nabeel|Matsui, William|Maitra, Anirban|Leach, Steven D | ||||||||||
| PMID: | 24096005 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Lett. 2014 Aug 28;351(1):151-61. | ||||||||||
| Title: | XMD8-92 inhibits pancreatic tumor xenograft growth via a DCLK1-dependent mechanism. | ||||||||||
| Author: | Sureban, Sripathi M|May, Randal|Weygant, Nathaniel|Qu, Dongfeng|Chandrakesan, Parthasarathy|Bannerman-Menson, Eddie|Ali, Naushad|Pantazis, Panayotis|Westphalen, Christoph B|Wang, Timothy C|Houchen, Courtney W | ||||||||||
| PMID: | 24880079 | ||||||||||
| 5. | |||||||||||
| Journal: | Mol Cancer. 2014 May 6;13:103. | ||||||||||
| Title: | Small molecule kinase inhibitor LRRK2-IN-1 demonstrates potent activity against colorectal and pancreatic cancer through inhibition of doublecortin-like kinase 1. | ||||||||||
| Author: | Weygant, Nathaniel|Qu, Dongfeng|Berry, William L|May, Randal|Chandrakesan, Parthasarathy|Owen, Daniel B|Sureban, Sripathi M|Ali, Naushad|Janknecht, Ralf|Houchen, Courtney W | ||||||||||
| PMID: | 24885928 | ||||||||||
| 6. | |||||||||||
| Journal: | Dig Dis Sci. 2015 Feb;60(2):509-13. | ||||||||||
| Title: | DCLK1 is detectable in plasma of patients with Barrett's esophagus and esophageal adenocarcinoma. | ||||||||||
| Author: | Whorton, Joshua|Sureban, Sripathi M|May, Randal|Qu, Dongfeng|Lightfoot, Stan A|Madhoun, Mohammad|Johnson, Milton|Tierney, William M|Maple, John T|Vega, Kenneth J|Houchen, Courtney W | ||||||||||
| PMID: | 25283374 | ||||||||||
| 7. | |||||||||||
| Journal: | PLoS One. 2015 Feb 27;10(2):e0118933. | ||||||||||
| Title: | Doublecortin-like kinase 1 is elevated serologically in pancreatic ductal adenocarcinoma and widely expressed on circulating tumor cells. | ||||||||||
| Author: | Qu, Dongfeng|Johnson, Jeremy|Chandrakesan, Parthasarathy|Weygant, Nathaniel|May, Randal|Aiello, Nicole|Rhim, Andrew|Zhao, Lichao|Zheng, Wei|Lightfoot, Stanley|Pant, Shubham|Irvan, Jeremy|Postier, Russell|Hocker, James|Hanas, Jay S|Ali, Naushad|Sureban, Sr | ||||||||||
| PMID: | 25723399 | ||||||||||
| 8. | |||||||||||
| Journal: | Oncotarget. 2015 Jun 20;6(17):15524-39. | ||||||||||
| Title: | Targeting pancreatitis blocks tumor-initiating stem cells and pancreatic cancer progression. | ||||||||||
| Author: | Mohammed, Altaf|Janakiram, Naveena B|Madka, Venkateshwar|Brewer, Misty|Ritchie, Rebekah L|Lightfoot, Stan|Kumar, Gaurav|Sadeghi, Michael|Patlolla, Jagan Mohan R|Yamada, Hiroshi Y|Cruz-Monserrate, Zobeida|May, Randal|Houchen, Courtney W|Steele, Vernon E|Ra | ||||||||||
| PMID: | 25906749 | ||||||||||
| 9. | |||||||||||
| Journal: | World J Stem Cells. 2015 Apr 26;7(3):547-55. | ||||||||||
| Title: | New insights into pancreatic cancer stem cells. | ||||||||||
| Author: | Rao, Chinthalapally V|Mohammed, Altaf | ||||||||||
| PMID: | 25914762 | ||||||||||
| 10. | |||||||||||
| Journal: | Oncotarget. 2015 Sep 29;6(29):27661-73. | ||||||||||
| Title: | Crocetinic acid inhibits hedgehog signaling to inhibit pancreatic cancer stem cells. | ||||||||||
| Author: | Rangarajan, Parthasarathy|Subramaniam, Dharmalingam|Paul, Santanu|Kwatra, Deep|Palaniyandi, Kanagaraj|Islam, Shamima|Harihar, Sitaram|Ramalingam, Satish|Gutheil, William|Putty, Sandeep|Pradhan, Rohan|Padhye, Subhash|Welch, Danny R|Anant, Shrikant|Dhar, An | ||||||||||
| PMID: | 26317547 | ||||||||||
| 11. | |||||||||||
| Journal: | Curr Pharmacol Rep. 2015 Aug 1;1(4):217-222. | ||||||||||
| Title: | Regulation of miRNAs by agents targeting the tumor stem cell markers DCLK1, MSI1, LGR5, and BMI1. | ||||||||||
| Author: | Sureban, Sripathi M|Qu, Dongfeng|Houchen, Courtney W | ||||||||||
| PMID: | 26366338 | ||||||||||
| 12. | |||||||||||
| Journal: | Sci Rep. 2015 Oct 8;5:14983. | ||||||||||
| Title: | Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical Implications. | ||||||||||
| Author: | O'Connell, Malaney R|Sarkar, Shubhashish|Luthra, Gurinder K|Okugawa, Yoshinaga|Toiyama, Yuji|Gajjar, Aakash H|Qiu, Suimin|Goel, Ajay|Singh, Pomila | ||||||||||
| PMID: | 26447334 | ||||||||||
| 13. | |||||||||||
| Journal: | Oncotarget. 2016 Jan 19;7(3):3217-32. | ||||||||||
| Title: | Quinomycin A targets Notch signaling pathway in pancreatic cancer stem cells. | ||||||||||
| Author: | Ponnurangam, Sivapriya|Dandawate, Prasad R|Dhar, Animesh|Tawfik, Ossama W|Parab, Rajashri R|Mishra, Prabhu Dutt|Ranadive, Prafull|Sharma, Rajiv|Mahajan, Girish|Umar, Shahid|Weir, Scott J|Sugumar, Aravind|Jensen, Roy A|Padhye, Subhash B|Balakrishnan, Arun| | ||||||||||
| PMID: | 26673007 | ||||||||||
| 14. | |||||||||||
| Journal: | Bioorg Med Chem Lett. 2016 Sep 15;26(18):4497-4503. | ||||||||||
| Title: | Nature-inspired design of tetraindoles: Optimization of the core structure and evaluation of structure-activity relationship. | ||||||||||
| Author: | Abdu-Allah, Hajjaj H M|Huang, Shih-Ting|Chang, Tzu Ting|Chen, Chia-Ling|Wu, Han-Chung|Li, Wen-Shan | ||||||||||
| PMID: | 27503685 | ||||||||||
| 15. | |||||||||||
| Journal: | Cancer Res. 2016 Jul 15;76(14):4090-9. | ||||||||||
| Title: | Survival of Patients with Gastrointestinal Cancers Can Be Predicted by a Surrogate microRNA Signature for Cancer Stem-like Cells Marked by DCLK1 Kinase. | ||||||||||
| Author: | Weygant, Nathaniel|Ge, Yang|Qu, Dongfeng|Kaddis, John S|Berry, William L|May, Randal|Chandrakesan, Parthasarathy|Bannerman-Menson, Edwin|Vega, Kenneth J|Tomasek, James J|Bronze, Michael S|An, Guangyu|Houchen, Courtney W | ||||||||||
| PMID: | 27287716 | ||||||||||
| 16. | |||||||||||
| Journal: | Cell Stem Cell. 2016 Apr 7;18(4):441-55. | ||||||||||
| Title: | Dclk1 Defines Quiescent Pancreatic Progenitors that Promote Injury-Induced Regeneration and Tumorigenesis. | ||||||||||
| Author: | Westphalen, C Benedikt|Takemoto, Yoshihiro|Tanaka, Takayuki|Macchini, Marina|Jiang, Zhengyu|Renz, Bernhard W|Chen, Xiaowei|Ormanns, Steffen|Nagar, Karan|Tailor, Yagnesh|May, Randal|Cho, Youngjin|Asfaha, Samuel|Worthley, Daniel L|Hayakawa, Yoku|Urbanska, A | ||||||||||
| PMID: | 27058937 | ||||||||||
| 17. | |||||||||||
| Journal: | PLoS One. 2016 Jan 14;11(1):e0146564. | ||||||||||
| Title: | Dominant Expression of DCLK1 in Human Pancreatic Cancer Stem Cells Accelerates Tumor Invasion and Metastasis. | ||||||||||
| Author: | Ito, Hiromitsu|Tanaka, Shinji|Akiyama, Yoshimitsu|Shimada, Shu|Adikrisna, Rama|Matsumura, Satoshi|Aihara, Arihiro|Mitsunori, Yusuke|Ban, Daisuke|Ochiai, Takanori|Kudo, Atsushi|Arii, Shigeki|Yamaoka, Shoji|Tanabe, Minoru | ||||||||||
| PMID: | 26764906 | ||||||||||
| 18. | |||||||||||
| Journal: | J Cell Mol Med. 2017 Sep;21(9):2055-2067. | ||||||||||
| Title: | Up-regulation of glycolysis promotes the stemness and EMT phenotypes in gemcitabine-resistant pancreatic cancer cells. | ||||||||||
| Author: | Zhao, Hengqiang|Duan, Qingke|Zhang, Zhengle|Li, Hehe|Wu, Heshui|Shen, Qiang|Wang, Chunyou|Yin, Tao | ||||||||||
| PMID: | 28244691 | ||||||||||
| 19. | |||||||||||
| Journal: | Ther Drug Monit. 2017 Jun;39(3):290-296. | ||||||||||
| Title: | Population Pharmacokinetics of Gemcitabine and dFdU in Pancreatic Cancer Patients Using an Optimal Design, Sparse Sampling Approach. | ||||||||||
| Author: | Serdjebi, Cindy|Gattacceca, Florence|Seitz, Jean-Francois|Fein, Francine|Gagniere, Johan|Francois, Eric|Abakar-Mahamat, Abakar|Deplanque, Gael|Rachid, Madani|Lacarelle, Bruno|Ciccolini, Joseph|Dahan, Laetitia | ||||||||||
| PMID: | 28346313 | ||||||||||
| 20. | |||||||||||
| Journal: | World J Gastroenterol. 2017 Aug 21;23(31):5764-5772. | ||||||||||
| Title: | Doublecortin and CaM kinase-like-1 as an independent prognostic factor in patients with resected pancreatic carcinoma. | ||||||||||
| Author: | Nishio, Kohei|Kimura, Kenjiro|Amano, Ryosuke|Nakata, Bunzo|Yamazoe, Sadaaki|Ohira, Go|Miura, Kotaro|Kametani, Naoki|Tanaka, Hiroaki|Muguruma, Kazuya|Hirakawa, Kosei|Ohira, Masaichi | ||||||||||
| PMID: | 28883702 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncol Rep. 2017 Nov;38(5):3238-3244. | ||||||||||
| Title: | Enhancement of cytotoxic effects of gemcitabine by Dclk1 inhibition through suppression of Chk1 phosphorylation in human pancreatic cancer cells. | ||||||||||
| Author: | Kawamura, Daichi|Takemoto, Yoshihiro|Nishimoto, Arata|Ueno, Koji|Hosoyama, Tohru|Shirasawa, Bungo|Tanaka, Toshiki|Kugimiya, Naruji|Harada, Eijiro|Hamano, Kimikazu | ||||||||||
| PMID: | 29048622 | ||||||||||
| 22. | |||||||||||
| Journal: | Cell Physiol Biochem. 2017;44(5):1867-1881. | ||||||||||
| Title: | MicroRNA-195 Suppresses the Progression of Pancreatic Cancer by Targeting DCLK1. | ||||||||||
| Author: | Zhou, Bin|Sun, Chuandong|Hu, Xiao|Zhan, Hanxiang|Zou, Hao|Feng, Yujie|Qiu, Fabo|Zhang, Shun|Wu, Liqun|Zhang, Bingyuan | ||||||||||
| PMID: | 29224010 | ||||||||||
| 23. | |||||||||||
| Journal: | Oncol Lett. 2017 Dec;14(6):7529-7537. | ||||||||||
| Title: | Expression and prognostic significance of doublecortin-like kinase 1 in patients with hepatocellular carcinoma. | ||||||||||
| Author: | Fan, Mengjiao|Qian, Niansong|Dai, Guanghai | ||||||||||
| PMID: | 29344199 | ||||||||||
| 24. | |||||||||||
| Journal: | Gastroenterology. 2018 Jul;155(1):210-223.e3. | ||||||||||
| Title: | Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells. | ||||||||||
| Author: | Zhang, Yu|Zoltan, Michelle|Riquelme, Erick|Xu, Hanwen|Sahin, Ismet|Castro-Pando, Susana|Montiel, Maria Fernanda|Chang, Kyle|Jiang, Zhengyu|Ling, Jianhua|Gupta, Sonal|Horne, William|Pruski, Melissa|Wang, Huamin|Sun, Shao-Cong|Lozano, Guillermina|Chiao, Pau | ||||||||||
| PMID: | 29604293 | ||||||||||