Literatures

Primary Site >> Colorectal Cancer

Gene >> CYP3A4

1.
Journal:	Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):4001-5.
Title:	P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans.
Author:	Schuetz, E G\|Schinkel, A H\|Relling, M V\|Schuetz, J D
PMID:	8633005

2.
Journal:	Mol Pharmacol. 1996 Feb;49(2):311-8.
Title:	Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells.
Author:	Schuetz, E G\|Beck, W T\|Schuetz, J D
PMID:	8632764

3.
Journal:	Mol Pharmacol. 1997 May;51(5):741-54.
Title:	Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.
Author:	Schmiedlin-Ren, P\|Thummel, K E\|Fisher, J M\|Paine, M F\|Lown, K S\|Watkins, P B
PMID:	9145912

4.
Journal:	Mutat Res. 1997 May 12;376(1-2):153-60.
Title:	The role of xenobiotic metabolizing enzymes in arylamine toxicity and carcinogenesis: functional and localization studies.
Author:	Windmill, K F\|McKinnon, R A\|Zhu, X\|Gaedigk, A\|Grant, D M\|McManus, M E
PMID:	9202751

5.
Journal:	Cancer Res. 1998 Feb 1;58(3):468-72.
Title:	Metabolism of irinotecan (CPT-11) by human hepatic microsomes: participation of cytochrome P-450 3A and drug interactions.
Author:	Haaz, M C\|Rivory, L\|Riche, C\|Vernillet, L\|Robert, J
PMID:	9458091

6.
Journal:	Drug Metab Dispos. 1998 Aug;26(8):769-74.
Title:	Biosynthesis of an aminopiperidino metabolite of irinotecan [7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecine] by human hepatic microsomes.
Author:	Haaz, M C\|Riche, C\|Rivory, L P\|Robert, J
PMID:	9698291

7.
Journal:	Biochem Pharmacol. 1999 Apr 15;57(8):951-4.
Title:	Decrease in hepatic cytochrome P450 after interleukin-2 immunotherapy.
Author:	Elkahwaji, J\|Robin, M A\|Berson, A\|Tinel, M\|Letteron, P\|Labbe, G\|Beaune, P\|Elias, D\|Rougier, P\|Escudier, B\|Duvillard, P\|Pessayre, D
PMID:	10086330

8.
Journal:	Biol Pharm Bull. 2000 Jul;23(7):810-4.
Title:	Sulfotransferases in a human colon carcinoma cell line, Caco-2.
Author:	Satoh, T\|Matsui, M\|Tamura, H
PMID:	10919357

9.
Journal:	Ann N Y Acad Sci. 2000;922:260-73.
Title:	DX-8951f: summary of phase I clinical trials.
Author:	De Jager, R\|Cheverton, P\|Tamanoi, K\|Coyle, J\|Ducharme, M\|Sakamoto, N\|Satomi, M\|Suzuki, M
PMID:	11193901

10.
Journal:	Free Radic Res. 2000 Sep;33(3):279-85.
Title:	Inhibitory effect of nitric oxide on the induction of cytochrome P450 3A4 mRNA by 1,25-dihydroxyvitamin D3 in Caco-2 cells.
Author:	Hara, H\|Mitani, N\|Adachi, T
PMID:	10993481

11.
Journal:	Cancer Chemother Pharmacol. 2000;45(4):298-304.
Title:	N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine (DPPE) a chemopotentiating and cytoprotective agent in clinical trials: interaction with histamine at cytochrome P450 3A4 and other isozymes that metabolize antineoplastic drugs.
Author:	Brandes, L J\|Queen, G M\|LaBella, F S
PMID:	10755318

12.
Journal:	J Clin Pharmacol. 2000 Jan;40(1):91-8.
Title:	Atorvastatin coadministration may increase digoxin concentrations by inhibition of intestinal P-glycoprotein-mediated secretion.
Author:	Boyd, R A\|Stern, R H\|Stewart, B H\|Wu, X\|Reyner, E L\|Zegarac, E A\|Randinitis, E J\|Whitfield, L
PMID:	10631627

13.
Journal:	J Biol Chem. 2001 May 4;276(18):14581-7. Epub 2001 Jan 31.
Title:	Nuclear receptor response elements mediate induction of intestinal MDR1 by rifampin.
Author:	Geick, A\|Eichelbaum, M\|Burk, O
PMID:	11297522

14.
Journal:	J Pharm Sci. 2001 Jun;90(6):722-31.
Title:	Hepatic extraction, metabolism, and biliary excretion of irinotecan in the isolated perfused rat liver.
Author:	Farabos, C\|Haaz, M C\|Gires, P\|Robert, J
PMID:	11357175

15.
Journal:	Pharm Res. 2001 Aug;18(8):1102-9.
Title:	Characterizing the expression of CYP3A4 and efflux transporters (P-gp, MRP1, and MRP2) in CYP3A4-transfected Caco-2 cells after induction with sodium butyrate and the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.
Author:	Cummins, C L\|Mangravite, L M\|Benet, L Z
PMID:	11587480

16.
Journal:	Br J Cancer. 2002 Sep 9;87(6):681-6.
Title:	Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: implications for drug therapy.
Author:	Martinez, C\|Garcia-Martin, E\|Pizarro, R M\|Garcia-Gamito, F J\|Agundez, J A G
PMID:	12237780

17.
Journal:	Biochem Biophys Res Commun. 2002 Dec 20;299(5):730-8.
Title:	Liganded VDR induces CYP3A4 in small intestinal and colon cancer cells via DR3 and ER6 vitamin D responsive elements.
Author:	Thompson, Paul D\|Jurutka, Peter W\|Whitfield, G Kerr\|Myskowski, Sandy M\|Eichhorst, Kristina R\|Dominguez, Carlos Encinas\|Haussler, Carol A\|Haussler, Mark R
PMID:	12470639

18.
Journal:	Biochem Biophys Res Commun. 2002 Nov 15;298(5):687-92.
Title:	Modulation of CYP3A4 expression by ceramide in human colon carcinoma HT-29 cells.
Author:	Chun, Young-Jin\|Lee, Sunghee\|Yang, Soon Ae\|Park, Sungsik\|Kim, Mie Young
PMID:	12419308

19.
Journal:	J Cell Biochem. 2002;87(2):147-59.
Title:	Ketoconazole potentiates terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 activity.
Author:	Wang, Ying-Jan\|Yu, Cheng-Fei\|Chen, Li-Ching\|Chen, Chien-Ho\|Lin, Jen-Kun\|Liang, Yu-Chih\|Lin, Chien-Huang\|Lin, Shyr-Yi\|Chen, Chin-Fa\|Ho, Yuan-Soon
PMID:	12244568

20.
Journal:	J Clin Oncol. 2002 Jul 15;20(14):3122-9.
Title:	Modulation of irinotecan metabolism by ketoconazole.
Author:	Kehrer, Diederik F S\|Mathijssen, Ron H J\|Verweij, Jaap\|de Bruijn, Peter\|Sparreboom, Alex
PMID:	12118026

21.
Journal:	Science. 2002 May 17;296(5571):1313-6.
Title:	Vitamin D receptor as an intestinal bile acid sensor.
Author:	Makishima, Makoto\|Lu, Timothy T\|Xie, Wen\|Whitfield, G Kerr\|Domoto, Hideharu\|Evans, Ronald M\|Haussler, Mark R\|Mangelsdorf, David J
PMID:	12016314

22.
Journal:	J Pharm Pharmacol. 2003 Jan;55(1):59-66.
Title:	Gene expression of CYP3A4, ABC-transporters (MDR1 and MRP1-MRP5) and hPXR in three different human colon carcinoma cell lines.
Author:	Pfrunder, Arabelle\|Gutmann, Heike\|Beglinger, Christoph\|Drewe, Jurgen
PMID:	12625868

23.
Journal:	Pharm Res. 2003 Feb;20(2):324-7.
Title:	Gene expression profiles of ABC transporters and cytochrome P450 3A in Caco-2 and human colorectal cancer cell lines.
Author:	Nakumura, Tsutomu\|Sakaeda, Toshiyuki\|Ohmoto, Nobuko\|Moriya, Yuka\|Komoto, Chiho\|Shirakawa, Toshiro\|Gotoh, Akinobu\|Matsuo, Masafumi\|Okmura, Katsuhiko
PMID:	12636175

24.
Journal:	Life Sci. 2003 May 30;73(2):141-9.
Title:	Induction of CYP3A4 by 1alpha,25-dyhydroxyvitamin D3 in HepG2 cells.
Author:	Elizondo, Guillermo\|Medina-Diaz, Irma M
PMID:	12738030

25.
Journal:	Life Sci. 2003 Nov 21;74(1):99-108.
Title:	Role of c-Myc in nitric oxide-mediated suppression of cytochrome P450 3A4.
Author:	Watabe, Masahiko\|Isogai, Yumiko\|Numazawa, Satoshi\|Yoshida, Takemi
PMID:	14575816

26.
Journal:	Toxicol Lett. 2003 Dec 15;146(1):75-81.
Title:	Activation of Fas receptor modulates cytochrome P450 3A4 expression in human colon carcinoma cells.
Author:	Chun, Young-Jin\|Park, Sungsik\|Yang, Soon Ae
PMID:	14615069

27.
Journal:	Am J Ther. 2004 Mar-Apr;11(2):114-23.
Title:	A Mathematical simulation to explain the coordinated functions of efflux and metabolism limiting the transport of anti-HIV agents across Caco-2 cells.
Author:	Patel, Jignesh\|Hussain, Azher\|Pal, Dhahanjay\|Mitra, Ashim K
PMID:	14999363

28.
Journal:	Drug Metab Dispos. 2004 Jul;32(7):685-8.
Title:	C-jun N-terminal kinase modulates 1,25-dihydroxyvitamin D3-induced cytochrome P450 3A4 gene expression.
Author:	Yasunami, Yoko\|Hara, Hirokazu\|Iwamura, Tatsunori\|Kataoka, Tadashi\|Adachi, Tetsuo
PMID:	15205382

29.
Journal:	Drug Metab Dispos. 2004 Aug;32(8):779-82.
Title:	Levothyroxine up-regulates P-glycoprotein independent of the pregnane X receptor.
Author:	Mitin, Tim\|Von Moltke, Lisa L\|Court, Michael H\|Greenblatt, David J
PMID:	15258100

30.
Journal:	Biochem Biophys Res Commun. 2004 Sep 3;321(4):909-15.
Title:	Loss of CYP3A7 gene induction by 1,25-dihydroxyvitamin D3 is caused by less binding of VDR to the proximal ER6 in CYP3A7 gene.
Author:	Hara, Hirokazu\|Yasunami, Yoko\|Adachi, Tetsuo
PMID:	15358113

31.
Journal:	J Natl Cancer Inst. 2004 Nov 3;96(21):1585-92.
Title:	Prediction of irinotecan pharmacokinetics by use of cytochrome P450 3A4 phenotyping probes.
Author:	Mathijssen, Ron H J\|de Jong, Floris A\|van Schaik, Ron H N\|Lepper, Erin R\|Friberg, Lena E\|Rietveld, Trinet\|de Bruijn, Peter\|Graveland, Wilfried J\|Figg, William D\|Verweij, Jaap\|Sparreboom, Alex
PMID:	15523087

32.
Journal:	Biochem Biophys Res Commun. 2005 Aug 19;334(1):9-15.
Title:	Promoter-, cell-, and ligand-specific transactivation responses of the VDRB1 isoform.
Author:	Esteban, Luis M\|Fong, Colette\|Amr, Deama\|Cock, Terrie-Anne\|Allison, Susan J\|Flanagan, Judith L\|Liddle, Chris\|Eisman, John A\|Gardiner, Edith M
PMID:	15992766

33.
Journal:	Pharmacogenet Genomics. 2005 Aug;15(8):535-46.
Title:	A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer.
Author:	Landi, Stefano\|Gemignani, Federica\|Moreno, Victor\|Gioia-Patricola, Lydie\|Chabrier, Amelie\|Guino, Elisabeth\|Navarro, Matilde\|de Oca, Javier\|Capella, Gabriel\|Canzian, Federico
PMID:	16006997

34.
Journal:	Kokuritsu Iyakuhin Shokuhin Eisei Kenkyusho Hokoku. 2005;(123):68-72.
Title:	[Network for the collection and distribution of Japanese liver tissues resected surgically for drug development and research use].
Author:	Sunouchi, Momoko\|Sakemi, Kazue\|Kubota, Kei-ichi\|Kita, Junji\|Kamikawa, Yuichiro\|Uchida, Kohsuke\|Miura, Shin-ichi\|Shigehara, Eiji\|Fujioka, Hiroyuki\|Ohno, Yasuo
PMID:	16541756

35.
Journal:	Expert Opin Drug Metab Toxicol. 2005 Aug;1(2):175-85.
Title:	Caco-2 cell permeability assays to measure drug absorption.
Author:	van Breemen, Richard B\|Li, Yongmei
PMID:	16922635

36.
Journal:	Cancer Chemother Pharmacol. 2005 Sep;56(3):248-54. Epub 2005 Apr 27.
Title:	P450 induction alters paclitaxel pharmacokinetics and tissue distribution with multiple dosing.
Author:	Gustafson, Daniel L\|Long, Michael E\|Bradshaw, Erica L\|Merz, Andrea L\|Kerzic, Patrick J
PMID:	15856231

37.
Journal:	Am J Pharmacogenomics. 2005;5(1):21-33.
Title:	Pharmacogenomics of fluorouracil, irinotecan, and oxaliplatin in hepatic metastases of colorectal cancer: clinical implications.
Author:	Lentz, Frederike\|Tran, Agnes\|Rey, Elisabeth\|Pons, Gerard\|Treluyer, Jean-Marc
PMID:	15727486

38.
Journal:	Br J Cancer. 2005 Jan 31;92(2):259-64.
Title:	Unfavourable expression of pharmacologic markers in mucinous colorectal cancer.
Author:	Glasgow, S C\|Yu, J\|Carvalho, L P\|Shannon, W D\|Fleshman, J W\|McLeod, H L
PMID:	15655543

39.
Journal:	J Cell Biochem. 2005 Apr 1;94(5):917-43.
Title:	Molecular and functional comparison of 1,25-dihydroxyvitamin D(3) and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4.
Author:	Jurutka, Peter W\|Thompson, Paul D\|Whitfield, G Kerr\|Eichhorst, Kristina R\|Hall, Neal\|Dominguez, Carlos Encinas\|Hsieh, Jui-Cheng\|Haussler, Carol A\|Haussler, Mark R
PMID:	15578590

40.
Journal:	Clin Cancer Res. 2005 May 15;11(10):3758-65.
Title:	Cytochrome p450 profile of colorectal cancer: identification of markers of prognosis.
Author:	Kumarakulasingham, Meera\|Rooney, Patrick H\|Dundas, Sinclair R\|Telfer, Colin\|Melvin, William T\|Curran, Stephanie\|Murray, Graeme I
PMID:	15897573

41.
Journal:	Curr Clin Pharmacol. 2006 Sep;1(3):311-23.
Title:	Clinical pharmacokinetics of irinotecan-based chemotherapy in colorectal cancer patients.
Author:	Di Paolo, Antonello\|Bocci, Guido\|Danesi, Romano\|Del Tacca, Mario
PMID:	18666754

42.
Journal:	Clin Cancer Res. 2006 Jul 15;12(14 Pt 2):4426s-4431s.
Title:	Strategies to enhance epidermal growth factor inhibition: targeting the mevalonate pathway.
Author:	Dimitroulakos, Jim\|Lorimer, Ian A\|Goss, Glenwood
PMID:	16857822

43.
Journal:	Planta Med. 2006 Jun;72(8):685-90. Epub 2006 Jun 1.
Title:	Hypericum perforatum: which constituents may induce intestinal MDR1 and CYP3A4 mRNA expression?
Author:	Gutmann, Heike\|Poller, Birk\|Buter, Karin Berger\|Pfrunder, Arabelle\|Schaffner, Willi\|Drewe, Jurgen
PMID:	16755466

44.
Journal:	Pharmacogenomics. 2006 Jun;7(4):575-85.
Title:	Acquired resistance to the anticancer drug paclitaxel is associated with induction of cytochrome P450 2C8.
Author:	Garcia-Martin, Elena\|Pizarro, Rosa M\|Martinez, Carmen\|Gutierrez-Martin, Yolanda\|Perez, Gabriela\|Jover, Ramiro\|Agundez, Jose Ag
PMID:	16753005

45.
Journal:	Clin Pharmacol Ther. 2006 May;79(5):449-60. Epub 2006 Apr 11.
Title:	Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans.
Author:	Becquemont, Laurent\|Glaeser, Hartmut\|Drescher, Siegfried\|Hitzl, Monika\|Simon, Nicolas\|Murdter, Thomas E\|Heinkele, Georg\|Hofmann, Ute\|Schaefer, Christian\|Burk, Oliver\|Verstuyft, Celine\|Eichelbaum, Michel\|Fromm, Martin F
PMID:	16678547

46.
Journal:	Phytother Res. 2007 Mar;21(3):239-44.
Title:	Effects of herbal medicinal products and food supplements on induction of CYP1A2, CYP3A4 and MDR1 in the human colon carcinoma cell line LS180.
Author:	Brandin, Helena\|Viitanen, Eila\|Myrberg, Olle\|Arvidsson, Ann-Kristin
PMID:	17163579

47.
Journal:	Inflamm Bowel Dis. 2007 Jun;13(6):710-20.
Title:	Decreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels.
Author:	Blokzijl, Hans\|Vander Borght, Sara\|Bok, Lisette I H\|Libbrecht, Louis\|Geuken, Mariska\|van den Heuvel, Fiona A J\|Dijkstra, Gerard\|Roskams, Tania A D\|Moshage, Han\|Jansen, Peter L M\|Faber, Klaas Nico
PMID:	17262809

48.
Journal:	Phytomedicine. 2007 Aug;14(7-8):498-507.
Title:	In vitro evaluation of human cytochrome P450 and P-glycoprotein-mediated metabolism of some phytochemicals in extracts and formulations of African potato.
Author:	Nair, Vipin D P\|Foster, Brian C\|Thor Arnason, J\|Mills, Edward J\|Kanfer, Isadore
PMID:	17336049

49.
Journal:	Eur J Clin Pharmacol. 2007 Jun;63(6):547-54. Epub 2007 Apr 3.
Title:	Identification of NR1I2 genetic variation using resequencing.
Author:	King, Cristi R\|Xiao, Ming\|Yu, Jinsheng\|Minton, Matthew R\|Addleman, Nicholas J\|Van Booven, Derek J\|Kwok, Pui-Yan\|McLeod, Howard L\|Marsh, Sharon
PMID:	17404718

50.
Journal:	BMC Cancer. 2007 Jul 2;7:118.
Title:	Genetic variability in CYP3A4 and CYP3A5 in primary liver, gastric and colorectal cancer patients.
Author:	Gervasini, Guillermo\|Garcia-Martin, Elena\|Ladero, Jose M\|Pizarro, Rosa\|Sastre, Javier\|Martinez, Carmen\|Garcia, Monserrat\|Diaz-Rubio, Manuel\|Agundez, Jose A G
PMID:	17605821

51.
Journal:	BMC Cancer. 2007 Jul 5;7:123.
Title:	Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk.
Author:	Bethke, Lara\|Webb, Emily\|Sellick, Gabrielle\|Rudd, Matthew\|Penegar, Stephen\|Withey, Laura\|Qureshi, Mobshra\|Houlston, Richard
PMID:	17615053

52.
Journal:	Cancer Res. 2007 Jul 15;67(14):6995-7002.
Title:	Tamoxifen forms DNA adducts in human colon after administration of a single [14C]-labeled therapeutic dose.
Author:	Brown, Karen\|Tompkins, Elaine M\|Boocock, David J\|Martin, Elizabeth A\|Farmer, Peter B\|Turteltaub, Kenneth W\|Ubick, Esther\|Hemingway, David\|Horner-Glister, Emma\|White, Ian N H
PMID:	17638912

53.
Journal:	Clin Ther. 2008 Aug;30(8):1385-407.
Title:	Drug interactions between chemotherapeutic regimens and antiepileptics.
Author:	Yap, Kevin Yi-Lwern\|Chui, Wai Keung\|Chan, Alexandre
PMID:	18803983

54.
Journal:	Br J Cancer. 2008 Oct 21;99(8):1239-45.
Title:	Pharmacokinetic and pharmacogenetic determinants of the activity and toxicity of irinotecan in metastatic colorectal cancer patients.
Author:	Rouits, E\|Charasson, V\|Petain, A\|Boisdron-Celle, M\|Delord, J-P\|Fonck, M\|Laurand, A\|Poirier, A-L\|Morel, A\|Chatelut, E\|Robert, J\|Gamelin, E
PMID:	18797458

55.
Journal:	Drug Metab Dispos. 2008 May;36(5):946-54.
Title:	Role of human pregnane X receptor in tamoxifen- and 4-hydroxytamoxifen-mediated CYP3A4 induction in primary human hepatocytes and LS174T cells.
Author:	Sane, Rucha S\|Buckley, Donna J\|Buckley, Arthur R\|Nallani, Srikanth C\|Desai, Pankaj B
PMID:	18299335

56.
Journal:	Invest New Drugs. 2008 Feb;26(1):25-34.
Title:	Pharmacological evaluation of C-3 modified Betulinic acid derivatives with potent anticancer activity.
Author:	Rajendran, Praveen\|Jaggi, Manu\|Singh, Manoj K\|Mukherjee, Rama\|Burman, Anand C
PMID:	17851638

57.
Journal:	Drug Metab Dispos. 2008 Jul;36(7):1283-90.
Title:	Effects of spice constituents on P-glycoprotein-mediated transport and CYP3A4-mediated metabolism in vitro.
Author:	Zhang, Wenxia\|Lim, Lee-Yong
PMID:	18385293

58.
Journal:	Eur J Pharm Sci. 2009 Mar 2;36(4-5):565-71.
Title:	PXR-mediated induction of human CYP3A4 and mouse Cyp3a11 by the glucocorticoid budesonide.
Author:	Zimmermann, Christian\|van Waterschoot, Robert A B\|Harmsen, Stefan\|Maier, Angelika\|Gutmann, Heike\|Schinkel, Alfred H
PMID:	19138736

59.
Journal:	J Nutr Biochem. 2010 Dec;21(12):1153-61.
Title:	Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention.
Author:	Bartik, Leonid\|Whitfield, G Kerr\|Kaczmarska, Magdalena\|Lowmiller, Christine L\|Moffet, Eric W\|Furmick, Julie K\|Hernandez, Zachary\|Haussler, Carol A\|Haussler, Mark R\|Jurutka, Peter W
PMID:	20153625

60.
Journal:	Endocr Relat Cancer. 2011 Mar 9;18(2):265-76.
Title:	Association of genetic polymorphisms in ESR2, HSD17B1, ABCB1, and SHBG genes with colorectal cancer risk.
Author:	Sainz, J\|Rudolph, A\|Hein, R\|Hoffmeister, M\|Buch, S\|von Schonfels, W\|Hampe, J\|Schafmayer, C\|Volzke, H\|Frank, B\|Brenner, H\|Forsti, A\|Hemminki, K\|Chang-Claude, J
PMID:	21317201

61.
Journal:	BMC Cancer. 2011 Feb 22;11:81.
Title:	Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells.
Author:	Habano, Wataru\|Gamo, Toshie\|Terashima, Jun\|Sugai, Tamotsu\|Otsuka, Koki\|Wakabayashi, Go\|Ozawa, Shogo
PMID:	21342487

62.
Journal:	Endocr Relat Cancer. 2011 Jun 8;18(3):371-84.
Title:	Modification of menopausal hormone therapy-associated colorectal cancer risk by polymorphisms in sex steroid signaling, metabolism and transport related genes.
Author:	Rudolph, Anja\|Sainz, Juan\|Hein, Rebecca\|Hoffmeister, Michael\|Frank, Bernd\|Forsti, Asta\|Brenner, Hermann\|Hemminki, Kari\|Chang-Claude, Jenny
PMID:	21490239

63.
Journal:	Mol Cancer. 2011 Jul 6;10:80.
Title:	Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells.
Author:	Basseville, Agnes\|Preisser, Laurence\|de Carne Trecesson, Sophie\|Boisdron-Celle, Michele\|Gamelin, Erick\|Coqueret, Olivier\|Morel, Alain
PMID:	21733184

64.
Journal:	Postepy Hig Med Dosw (Online). 2011 Jun 17;65:367-76.
Title:	[Expression systems of cytochrome P450 proteins in studies of drug metabolism in vitro].
Author:	Pawlowska, Monika\|Augustin, Ewa
PMID:	21734321

65.
Journal:	Cancers (Basel). 2011 Mar 22;3(1):1467-79.
Title:	Overexpression of CYP3A4 in a COLO 205 Colon Cancer Stem Cell Model in vitro.
Author:	Olszewski, Ulrike\|Liedauer, Richard\|Ausch, Christoph\|Thalhammer, Theresia\|Hamilton, Gerhard
PMID:	24212669

66.
Journal:	Acta Medica (Hradec Kralove). 2012;55(4):153-9.
Title:	Predictors of irinotecan toxicity and efficacy in treatment of metastatic colorectal cancer.
Author:	Paulik, Adam\|Grim, Jiri\|Filip, Stanislav
PMID:	23631285

67.
Journal:	Org Med Chem Lett. 2012 Jun 11;2(1):21.
Title:	Cytotoxic and potent CYP1 inhibitors from the marine algae Cymopolia barbata.
Author:	Badal, Simone\|Gallimore, Winklet\|Huang, George\|Tzeng, Tzuen-Rong Jeremy\|Delgoda, Rupika
PMID:	22686946

68.
Journal:	Curr Drug Targets. 2013 Jun;14(7):777-97.
Title:	Therapeutic targeting of CPT-11 induced diarrhea: a case for prophylaxis.
Author:	Swami, Umang\|Goel, Sanjay\|Mani, Sridhar
PMID:	23597015

69.
Journal:	Clin Cancer Res. 2013 Sep 1;19(17):4832-42.
Title:	Phase I safety, pharmacokinetic and pharmacodynamic evaluation of the vascular disrupting agent ombrabulin (AVE8062) in patients with advanced solid tumors.
Author:	Sessa, Cristiana\|Lorusso, Patricia\|Tolcher, Anthony\|Farace, Francoise\|Lassau, Nathalie\|Delmonte, Angelo\|Braghetti, Antonio\|Bahleda, Rastislav\|Cohen, Patrick\|Hospitel, Marie\|Veyrat-Follet, Christine\|Soria, Jean-Charles
PMID:	23833302

70.
Journal:	Cancer Causes Control. 2014 May;25(5):561-70.
Title:	Genetic variation in vitamin D-related genes and risk of colorectal cancer in African Americans.
Author:	Pibiri, Fabio\|Kittles, Rick A\|Sandler, Robert S\|Keku, Temitope O\|Kupfer, Sonia S\|Xicola, Rosa M\|Llor, Xavier\|Ellis, Nathan A
PMID:	24562971

71.
Journal:	Cell Biosci. 2014 Apr 1;4(1):17.
Title:	Tissue-specific regulation of pregnane X receptor in cancer development and therapy.
Author:	Robbins, Delira\|Chen, Taosheng
PMID:	24690092

72.
Journal:	Cell Physiol Biochem. 2014;33(5):1400-10.
Title:	Short-term effects of oral administration of Pistacia lentiscus oil on tissue-specific toxicity and drug metabolizing enzymes in mice.
Author:	Attoub, Samir\|Karam, Sherif M\|Nemmar, Abderrahim\|Arafat, Kholoud\|John, Annie\|Al-Dhaheri, Wafa\|Al Sultan, Mahmood Ahmed\|Raza, Haider
PMID:	24853661

73.
Journal:	Oncol Lett. 2014 Dec;8(6):2407-2416.
Title:	Effects of co-treatment with sulforaphane and autophagy modulators on uridine 5'-diphospho-glucuronosyltransferase 1A isoforms and cytochrome P450 3A4 expression in Caco-2 human colon cancer cells.
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