Literatures

Primary Site >> Liver Cancer

Gene >> CYP2E1

1.
Journal:	Pharmacogenetics. 1995;5 Spec No:S141-4.
Title:	Cytochrome P4502E1 (CYP2E1) genetic polymorphism in a case-control study of gastric cancer and liver disease.
Author:	Kato, S\|Onda, M\|Matsukura, N\|Tokunaga, A\|Tajiri, T\|Kim, D Y\|Tsuruta, H\|Matsuda, N\|Yamashita, K\|Shields, P G
PMID:	7581484

2.
Journal:	Gastroenterology. 1995 Oct;109(4):1266-73.
Title:	Cytochrome P450 2E1 and glutathione S-transferase M1 polymorphisms and susceptibility to hepatocellular carcinoma.
Author:	Yu, M W\|Gladek-Yarborough, A\|Chiamprasert, S\|Santella, R M\|Liaw, Y F\|Chen, C J
PMID:	7557094

3.
Journal:	Gut. 1996 Aug;39(2):330-3.
Title:	RsaI polymorphism at the cytochrome P4502E1 locus and risk of hepatocellular carcinoma.
Author:	Ladero, J M\|Agundez, J A\|Rodriguez-Lescure, A\|Diaz-Rubio, M\|Benitez, J
PMID:	8977352

4.
Journal:	Eur J Biochem. 1996 Jun 1;238(2):400-9.
Title:	trans-Acting factors, detoxication enzymes and hepatitis B virus replication in a novel set of human hepatoma cell lines.
Author:	Le Jossic, C\|Glaise, D\|Corcos, L\|Diot, C\|Dezier, J F\|Fautrel, A\|Guguen-Guillouzo, C
PMID:	8681951

5.
Journal:	Int J Cancer. 1997 May 29;71(5):737-40.
Title:	Lack of association of cytochrome P450 2E1 genetic polymorphisms with the risk of human hepatocellular carcinoma.
Author:	Lee, H S\|Yoon, J H\|Kamimura, S\|Iwata, K\|Watanabe, H\|Kim, C Y
PMID:	9180139

6.
Journal:	Environ Health Perspect. 1997 Jun;105 Suppl 4:749-54.
Title:	Interaction between dose and susceptibility to environmental cancer: a short review.
Author:	Hietanen, E\|Husgafvel-Pursiainen, K\|Vainio, H
PMID:	9255556

7.
Journal:	Int J Oncol. 1998 May;12(5):1049-53.
Title:	Differential expression of cytochrome P4502E1 (CYP2E1) in Morris hepatomas and livers of tumor bearing rats.
Author:	Hu, J J\|Hong, J Y\|Lea, M A\|Yang, C S
PMID:	9538127

8.
Journal:	Biochem Pharmacol. 1999 Apr 15;57(8):951-4.
Title:	Decrease in hepatic cytochrome P450 after interleukin-2 immunotherapy.
Author:	Elkahwaji, J\|Robin, M A\|Berson, A\|Tinel, M\|Letteron, P\|Labbe, G\|Beaune, P\|Elias, D\|Rougier, P\|Escudier, B\|Duvillard, P\|Pessayre, D
PMID:	10086330

9.
Journal:	Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2001 Feb;18(1):62-5.
Title:	[Progress in researches on the relationship between genetic polymorphisms of alcohol-metabolizing enzymes and cancers].
Author:	Zhang, Z\|Bian, J
PMID:	11172647

10.
Journal:	Am J Addict. 2001;10(s1):s29-s50.
Title:	Liver diseases by alcohol and hepatitis C: early detection and new insights in pathogenesis lead to improved treatment.
Author:	Lieber, C S
PMID:	11268819

11.
Journal:	Alcohol Clin Exp Res. 2001 May;25(5 Suppl ISBRA):225S-229S.
Title:	The ubiquitin-proteasome 26s pathway in liver cell protein turnover: effect of ethanol and drugs.
Author:	French, S W\|Mayer, R J\|Bardag-Gorce, F\|Ingelman-Sundberg, M\|Rouach, H\|Neve And, E\|Higashitsuji, H
PMID:	11391075

12.
Journal:	Hepatology. 2002 Aug;36(2):433-8.
Title:	Underexpression of mRNA in human hepatocellular carcinoma focusing on eight loci.
Author:	Kinoshita, Moritoshi\|Miyata, Masahiko
PMID:	12143053

13.
Journal:	J Nippon Med Sch. 2002 Jun;69(3):243-51.
Title:	Immunohistochemical study of CYP2E1 in hepatocellular carcinoma carcinogenesis: examination with newly prepared anti-human CYP2E1 antibody.
Author:	Hirose, Yoichiro\|Naito, Zenya\|Kato, Shunji\|Onda, Masahiko\|Sugisaki, Yuichi
PMID:	12068315

14.
Journal:	FASEB J. 2002 Aug;16(10):1292-4.
Title:	Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.
Author:	Martinez-Chantar, Maria L\|Corrales, Fernando J\|Martinez-Cruz, L Alfonso\|Garcia-Trevijano, Elena R\|Huang, Zong-Zhi\|Chen, Lixin\|Kanel, Gary\|Avila, Matias A\|Mato, Jose M\|Lu, Shelly C
PMID:	12060674

15.
Journal:	Int J Clin Pharmacol Ther. 2002 Mar;40(3):120-4.
Title:	Assessment of frequencies of lifestyle factors and polymorphisms of drug-metabolizing enzymes (NAT2, CYP2E1) in human hepatocellular carcinoma (HCC) patients in a department of surgical medicine--a pilot investigation.
Author:	Farker, K\|Schotte, U\|Scheele, J\|Hoffmann, A
PMID:	11911601

16.
Journal:	Int J Cancer. 2003 Apr 10;104(3):310-7.
Title:	CYP enzyme polymorphisms and susceptibility to HCV-related chronic liver disease and liver cancer.
Author:	Silvestri, Laura\|Sonzogni, Laura\|De Silvestri, Annalisa\|Gritti, Chiara\|Foti, Luciana\|Zavaglia, Claudio\|Leveri, Michela\|Cividini, Agostino\|Mondelli, Mario U\|Civardi, Emilio\|Silini, Enrico M
PMID:	12569554

17.
Journal:	J Pharmacol Exp Ther. 2003 Mar;304(3):1048-54.
Title:	Mechanisms of down-regulation of CYP2E1 expression by inflammatory cytokines in rat hepatoma cells.
Author:	Hakkola, Jukka\|Hu, Yin\|Ingelman-Sundberg, Magnus
PMID:	12604681

18.
Journal:	J Cancer Res Clin Oncol. 2003 Jun;129(6):355-60.
Title:	Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and the risk of hepatocellular carcinoma.
Author:	Munaka, Masahiro\|Kohshi, Kiyotaka\|Kawamoto, Toshihiro\|Takasawa, Shin\|Nagata, Naoki\|Itoh, Hideaki\|Oda, Susumu\|Katoh, Takahiko
PMID:	12759747

19.
Journal:	Scand J Gastroenterol. 2003 Aug;38(8):886-93.
Title:	Genetic polymorphisms of aldehyde dehydrogenase 2, cytochrome p450 2E1 for liver cancer risk in HCV antibody-positive japanese patients and the variations of CYP2E1 mRNA expression levels in the liver due to its polymorphism.
Author:	Kato, S\|Tajiri, T\|Matsukura, N\|Matsuda, N\|Taniai, N\|Mamada, H\|Yoshida, H\|Kiyam, T\|Naito, Z
PMID:	12940444

20.
Journal:	Alcohol. 2003 Jun;30(2):93-7.
Title:	Role of iron in alcoholic liver disease: introduction and summary of the symposium.
Author:	Purohit, Vishnudutt\|Russo, Denise\|Salin, Marvin
PMID:	12957291

21.
Journal:	Indian J Exp Biol. 2003 Nov;41(11):1226-32.
Title:	Antituberculosis drug-induced hepatitis: risk factors, prevention and management.
Author:	Hussain, Z\|Kar, P\|Husain, S A
PMID:	15332488

22.
Journal:	Curr Drug Metab. 2004 Jun;5(3):211-24.
Title:	Cytochrome P450 gene polymorphism and cancer.
Author:	Agundez, Jose A G
PMID:	15180491

23.
Journal:	Curr Drug Metab. 2004 Jun;5(3):273-82.
Title:	Cytochrome P450 and liver diseases.
Author:	Villeneuve, J-P\|Pichette, V
PMID:	15180496

24.
Journal:	Int J Cancer. 2004 Sep 10;111(4):494-500.
Title:	Decreased expression of cytochrome P450 2E1 is associated with poor prognosis of hepatocellular carcinoma.
Author:	Ho, Jenny C\|Cheung, Siu Tim\|Leung, Ka Ling\|Ng, Irene O\|Fan, Sheung Tat
PMID:	15239125

25.
Journal:	Virology. 2005 Feb 5;332(1):130-44.
Title:	Molecular profiling of early stage liver fibrosis in patients with chronic hepatitis C virus infection.
Author:	Bieche, Ivan\|Asselah, Tarik\|Laurendeau, Ingrid\|Vidaud, Dominique\|Degot, Claude\|Paradis, Valerie\|Bedossa, Pierre\|Valla, Dominique-Charles\|Marcellin, Patrick\|Vidaud, Michel
PMID:	15661146

26.
Journal:	Virol J. 2005 Dec 2;2:89.
Title:	Effect of ethanol on innate antiviral pathways and HCV replication in human liver cells.
Author:	Plumlee, Courtney R\|Lazaro, Catherine A\|Fausto, Nelson\|Polyak, Stephen J
PMID:	16324217

27.
Journal:	Cancer Sci. 2005 Nov;96(11):747-57.
Title:	Dose-dependence of promotion of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-induced rat hepatocarcinogenesis by ethanol: evidence for a threshold.
Author:	Kushida, Masahiko\|Wanibuchi, Hideki\|Morimura, Keiichirou\|Kinoshita, Anna\|Kang, Jin Seok\|Puatanachokchai, Rawiwan\|Wei, Min\|Funae, Yoshihiko\|Fukushima, Shoji
PMID:	16271068

28.
Journal:	Carcinogenesis. 2005 Jan;26(1):239-48.
Title:	A beta-catenin-dependent pathway regulates expression of cytochrome P450 isoforms in mouse liver tumors.
Author:	Loeppen, Sandra\|Koehle, Christoph\|Buchmann, Albrecht\|Schwarz, Michael
PMID:	15471898

29.
Journal:	Int J Oncol. 2005 Sep;27(3):661-7.
Title:	Patterns of expression of cytochrome P450 genes in progression of hepatitis C virus-associated hepatocellular carcinoma.
Author:	Tsunedomi, Ryouichi\|Iizuka, Norio\|Hamamoto, Yoshihiko\|Uchimura, Shunji\|Miyamoto, Takanobu\|Tamesa, Takao\|Okada, Toshimasa\|Takemoto, Norikazu\|Takashima, Motonari\|Sakamoto, Kazuhiko\|Hamada, Kenji\|Yamada-Okabe, Hisafumi\|Oka, Masaaki
PMID:	16077914

30.
Journal:	Life Sci. 2006 Aug 8;79(11):1100-7.
Title:	High-fat emulsion-induced rat model of nonalcoholic steatohepatitis.
Author:	Zou, Yuhong\|Li, Jun\|Lu, Chao\|Wang, Jianqing\|Ge, Jinfang\|Huang, Yan\|Zhang, Lei\|Wang, Yuanyuan
PMID:	16624332

31.
Journal:	Int J Gastrointest Cancer. 2006;37(2-3):79-83.
Title:	*Identification of CYP2C92 allele in HepG2 cell line.**
Author:	Chen, Jiezhong\|Raymond, Kenneth
PMID:	17827526

32.
Journal:	J Nutr Biochem. 2007 May;18(5):348-54.
Title:	Docosahexaenoic acid induces apoptosis in CYP2E1-containing HepG2 cells by activating the c-Jun N-terminal protein kinase related mitochondrial damage.
Author:	Lee, Myoungsook\|Bae, Myung-Ae
PMID:	16963249

33.
Journal:	J Environ Sci Health C Environ Carcinog Ecotoxicol Rev. 2007
Title:	Postulated carbon tetrachloride mode of action: a review.
Author:	Manibusan, Mary K\|Odin, Marc\|Eastmond, David A
PMID:	17763046

34.
Journal:	Cancer Res. 2007 Dec 1;67(23):11141-6.
Title:	Role of CYP2E1 in diethylnitrosamine-induced hepatocarcinogenesis in vivo.
Author:	Kang, Jin Seok\|Wanibuchi, Hideki\|Morimura, Keiichirou\|Gonzalez, Frank J\|Fukushima, Shoji
PMID:	18056438

35.
Journal:	Food Chem Toxicol. 2008 Apr;46(4):1230-8.
Title:	Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver.
Author:	Huber, Wolfgang W\|Rossmanith, Walter\|Grusch, Michael\|Haslinger, Elisabeth\|Prustomersky, Sonja\|Peter-Vorosmarty, Barbara\|Parzefall, Wolfram\|Scharf, Gerlinde\|Schulte-Hermann, Rolf
PMID:	17983700

36.
Journal:	Cancer Biol Ther. 2008 Aug;7(8):1280-7. Epub 2008 Aug 13.
Title:	Overexpression of CYP2E1 enhances sensitivity of hepG2 cells to fas-mediated cytotoxicity.
Author:	Yan, Qing-Guo\|Shi, Jian-Guo\|Zhang, Feng\|Zhao, Qing-Tao\|Pang, Xiao-Wen\|Chen, Rui\|Hu, Pei-Zhen\|Li, Qin-Long\|Wang, Zhe\|Huang, Gao-Sheng
PMID:	18497573

37.
Journal:	Arzneimittelforschung. 2008;58(5):225-41.
Title:	Ciprofibrate, clofibric acid and respective glycinate derivatives. Effects of a four-week treatment on male lean and obese Zucker rats.
Author:	Lupp, Amelie\|Karge, Elke\|Deufel, Thomas\|Oelschlagers, Herbert\|Fleck, Christian
PMID:	18589557

38.
Journal:	Hepatology. 2009 Aug;50(2):453-61.
Title:	Ethanol-induced cytochrome P4502E1 causes carcinogenic etheno-DNA lesions in alcoholic liver disease.
Author:	Wang, Ying\|Millonig, Gunda\|Nair, Jagadeesan\|Patsenker, Eleonora\|Stickel, Felix\|Mueller, Sebastian\|Bartsch, Helmut\|Seitz, Helmut K
PMID:	19489076

39.
Journal:	Neoplasia. 2009 Oct;11(10):1003-11.
Title:	Using acetaminophen's toxicity mechanism to enhance cisplatin efficacy in hepatocarcinoma and hepatoblastoma cell lines.
Author:	Neuwelt, Alexander J\|Wu, Y Jeffrey\|Knap, Narcyz\|Losin, Marcin\|Neuwelt, Edward A\|Pagel, Michael A\|Warmann, Steven\|Fuchs, Joerg\|Czauderna, Piotr\|Wozniak, Michal
PMID:	19794959

40.
Journal:	Carcinogenesis. 2009 Oct;30(10):1729-34.
Title:	Interaction between cytochrome P450 1A2 genetic polymorphism and cigarette smoking on the risk of hepatocellular carcinoma in a Japanese population.
Author:	Imaizumi, Takeshi\|Higaki, Yasuki\|Hara, Megumi\|Sakamoto, Tatsuhiko\|Horita, Mikako\|Mizuta, Toshihiko\|Eguchi, Yuichiro\|Yasutake, Tsutomu\|Ozaki, Iwata\|Yamamoto, Kyosuke\|Onohara, Shingo\|Kawazoe, Seiji\|Shigematsu, Hirohisa\|Koizumi, Shunzo\|Kudo, Sho\|Tanaka, Keit
PMID:	19643819

41.
Journal:	World J Gastroenterol. 2009 Jul 28;15(28):3462-71.
Title:	Alcoholic liver disease and hepatitis C: a frequently underestimated combination.
Author:	Mueller, Sebastian\|Millonig, Gunda\|Seitz, Helmut K
PMID:	19630099

42.
Journal:	Zhonghua Liu Xing Bing Xue Za Zhi. 2009 Feb;30(2):151-5.
Title:	[Study on the relationship between familial clustering of hepatocellular carcinoma and polymorphism of cytochrome P450 2E1 gene in Zhuang population, Guangxi].
Author:	Sheng, Ying\|Huang, Tian-ren\|Zhang, Zhen-quan\|Deng, Wei\|Yu, Jia-hua\|Zhang, Chun-yan\|Zhou, De-nan\|Li, Ji-lin\|Ye, Si-yuan\|Liang, Ren-xiang\|Wei, Zhong-liang
PMID:	19565876

43.
Journal:	Basic Clin Pharmacol Toxicol. 2010 Mar;106(3):173-9.
Title:	Mode of action considerations in the quantitative assessment of tumour responses in the liver.
Author:	Boobis, Alan R
PMID:	20030633

44.
Journal:	Carcinogenesis. 2010 Apr;31(4):648-53.
Title:	Prevalence and persistence of chromosomal damage and susceptible genotypes of metabolic and DNA repair genes in Chinese vinyl chloride-exposed workers.
Author:	Ji, Fang\|Wang, Wei\|Xia, Zhao-Lin\|Zheng, Ying-Jia\|Qiu, Yu-Lan\|Wu, Fen\|Miao, Wen-Bin\|Jin, Ru-Feng\|Qian, Ji\|Jin, Li\|Zhu, Yi-Liang\|Christiani, David C
PMID:	20100738

45.
Journal:	Wei Sheng Yan Jiu. 2010 Jan;39(1):42-5.
Title:	[Association between aldehyde dehydrogenase-2/cytochrome P450 2E1 genetic polymorphism and habit of alcohol drinking and the susceptibility of hepatocellular carcinoma].
Author:	Ye, Xinping\|Peng, Tao\|Liu, Tangwei\|Su, Zhixiong\|Xiao, Kaiyin\|Shang, Liming\|Su, Ming\|Li, Lequn
PMID:	20364586

46.
Journal:	Exp Biol Med (Maywood). 2010 Jan;235(1):32-9.
Title:	Histone modification-mediated CYP2E1 gene expression and apoptosis of HepG2 cells.
Author:	Yang, Hui\|Nie, Yuqiang\|Li, Yuyuan\|Wan, Yu-Jui Yvonne
PMID:	20404016

47.
Journal:	Chem Biol Interact. 2010 Dec 5;188(3):367-75.
Title:	Formation of acetaldehyde-derived DNA adducts due to alcohol exposure.
Author:	Yu, Hsu-Sheng\|Oyama, Tsunehiro\|Isse, Toyohi\|Kitagawa, Kyoko\|Pham, Thi-Thu-Phuong\|Tanaka, Masayuki\|Kawamoto, Toshihiro
PMID:	20813101

48.
Journal:	Alcohol Clin Exp Res. 2011 Dec;35(12):2216-25.
Title:	Alcohol induces liver neoplasia in a novel alcohol-preferring rat model.
Author:	Yip-Schneider, Michele T\|Doyle, Courtney J\|McKillop, Iain H\|Wentz, Sabrina C\|Brandon-Warner, Elizabeth\|Matos, Jesus M\|Sandrasegaran, Kumaresan\|Saxena, Romil\|Hennig, Matthew E\|Wu, Huangbing\|Waters, Joshua A\|Klein, Patrick J\|Froehlich, Janice C\|Schmidt, C M
PMID:	21790668

49.
Journal:	Invest New Drugs. 2011 Oct;29(5):760-7.
Title:	An in vitro comparative study with furyl-1,4-quinones endowed with anticancer activities.
Author:	Benites, Julio\|Valderrama, Jaime A\|Taper, Henryk\|Buc Calderon, Pedro
PMID:	20237828

50.
Journal:	Tumour Biol. 2012 Aug;33(4):979-84.
Title:	CYP2E1 PstI/RsaI polymorphism and interaction with alcohol consumption in hepatocellular carcinoma susceptibility: evidence from 1,661 cases and 2,317 controls.
Author:	Liu, Chibo\|Wang, Haibao\|Pan, Chunqin\|Shen, Jianmin\|Liang, Yong
PMID:	22249978

51.
Journal:	Asian Pac J Cancer Prev. 2012;13(10):4915-21.
Title:	CYP2E1 RsaI/PstI polymorphism and liver cancer risk among east Asians: a HuGE review and meta-analysis.
Author:	Tian, Zhong\|Li, Yi-Ling\|Zhao, Lin\|Zhang, Chen-Liang
PMID:	23244081

52.
Journal:	Mol Med Rep. 2012 Aug;6(2):416-20.
Title:	Cytochrome P450 2E1 variable number tandem repeat polymorphisms and health risks: a genotype-phenotype study in cancers associated with drinking and/or smoking.
Author:	Catanzaro, Irene\|Naselli, Flores\|Saverini, Marghereth\|Giacalone, Antonio\|Montalto, Giuseppe\|Caradonna, Fabio
PMID:	22614694

53.
Journal:	Surg Endosc. 2013 Jan;27(1):246-55.
Title:	Diet-induced obesity and ethanol impair progression of hepatocellular carcinoma in a mouse mesenteric vein injection model.
Author:	Thompson, Kyle J\|Swan, Ryan Z\|Iannitti, David A\|McKillop, Iain H\|Sindram, David
PMID:	22806512

54.
Journal:	Gene. 2013 May 1;519(2):231-7.
Title:	Genetic polymorphisms of CYP2E1 and DNA repair genes HOGG1 and XRCC1: association with hepatitis B related advanced liver disease and cancer.
Author:	Bose, Sujoy\|Tripathi, Dinesh M\|Sukriti\|Sakhuja, Puja\|Kazim, Syed N\|Sarin, Shiv K
PMID:	23454624

55.
Journal:	In Vitro Cell Dev Biol Anim. 2013 Sep;49(8):619-25.
Title:	Alcohol dehydrogenase and cytochrome P450 2E1 can be induced by long-term exposure to ethanol in cultured liver HEP-G2 cells.
Author:	Balusikova, Kamila\|Kovar, Jan
PMID:	23824954

56.
Journal:	Chin J Cancer Res. 2013 Jun;25(3):269-71.
Title:	Pharmacological blockage of CYP2E1 and alcohol-mediated liver cancer: is the time ready?
Author:	Mueller, Sebastian
PMID:	23825901

57.
Journal:	PLoS One. 2013 Sep 16;8(9):e73591.
Title:	Aldose reductase is involved in the development of murine diet-induced nonalcoholic steatohepatitis.
Author:	Qiu, Longxin\|Lin, Jianhui\|Ying, Miao\|Chen, Weiqiang\|Yang, Jinmei\|Deng, Tiantian\|Chen, Jinfeng\|Shi, Duanyu\|Yang, James Y
PMID:	24066058

58.
Journal:	PLoS One. 2013 Nov 20;8(11):e79826.
Title:	Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected tumor samples.
Author:	Caboux, Elodie\|Paciencia, Maria\|Durand, Geoffroy\|Robinot, Nivonirina\|Wozniak, Magdalena B\|Galateau-Salle, Francoise\|Byrnes, Graham\|Hainaut, Pierre\|Le Calvez-Kelm, Florence
PMID:	24278187

59.
Journal:	Zhonghua Gan Zang Bing Za Zhi. 2014 Feb;22(2):122-7.
Title:	[Mechanism and clinical significance of HBx-mediated inhibition of CYP2E1 expression in the human HepG2 hepatoma cell line].
Author:	Xie, Bin\|Wu, Gang\|Chen, Ping\|Liu, Kun\|Yuan, Tao
PMID:	24735595

60.
Journal:	PLoS One. 2014 Sep 19;9(9):e107913.
Title:	HBx inhibits CYP2E1 gene expression via downregulating HNF4alpha in human hepatoma cells.
Author:	Liu, Hongming\|Lou, Guiyu\|Li, Chongyi\|Wang, Xiaodong\|Cederbaum, Arthur I\|Gan, Lixia\|Xie, Bin
PMID:	25238230

61.
Journal:	Mol Biol Rep. 2014 Nov;41(11):7645-50.
Title:	Cytochrome P450 2E1 gene polymorphism and alcohol drinking on the risk of hepatocellular carcinoma: a meta-analysis.
Author:	Liu, Wei\|Tian, Fang\|Dai, Liping\|Chai, Yurong
PMID:	25185993

62.
Journal:	J Toxicol Sci. 2014 Aug;39(4):609-14.
Title:	Effects of arecoline on hepatic cytochrome P450 activity and oxidative stress.
Author:	Run-mei, Xiao\|Jun-jun, Wang\|Jing-ya, Chen\|Li-juan, Sun\|Yong, Chen
PMID:	25056785

63.
Journal:	World J Gastroenterol. 2014 Jul 14;20(26):8681-90.
Title:	Expression of P450 and nuclear receptors in normal and end-stage Chinese livers.
Author:	Chen, Hong\|Shen, Zhong-Yang\|Xu, Wang\|Fan, Tie-Yan\|Li, Jun\|Lu, Yuan-Fu\|Cheng, Ming-Liang\|Liu, Jie
PMID:	25024626

64.
Journal:	Cell Physiol Biochem. 2014;33(5):1400-10.
Title:	Short-term effects of oral administration of Pistacia lentiscus oil on tissue-specific toxicity and drug metabolizing enzymes in mice.
Author:	Attoub, Samir\|Karam, Sherif M\|Nemmar, Abderrahim\|Arafat, Kholoud\|John, Annie\|Al-Dhaheri, Wafa\|Al Sultan, Mahmood Ahmed\|Raza, Haider
PMID:	24853661

65.
Journal:	Int J Mol Sci. 2014 Mar 7;15(3):4126-41.
Title:	Alcohol induced hepatic degeneration in a hepatitis C virus core protein transgenic mouse model.
Author:	Noh, Dong-Hyung\|Lee, Eun-Joo\|Kim, Ah-Young\|Lee, Eun-Mi\|Min, Chang-Woo\|Kang, Kyung-Ku\|Lee, Myeong-Mi\|Kim, Sang-Hyeob\|Sung, Soo-Eun\|Hwang, Meeyul\|Yu, Dae-Yeul\|Jeong, Kyu-Shik
PMID:	24608925

66.
Journal:	Food Chem Toxicol. 2014 Apr;66:194-202.
Title:	Curcumin and (-)-epigallocatechin-3-gallate attenuate acrylamide-induced proliferation in HepG2 cells.
Author:	Shan, Xiaoyun\|Li, Yuan\|Meng, Xulian\|Wang, Pengqi\|Jiang, Pan\|Feng, Qing
PMID:	24508477

67.
Journal:	Tumour Biol. 2014 Apr;35(4):3671-7.
Title:	Liver cancer-related gene CYP2E1 expression in HBV transgenic mice with acute liver injury.
Author:	Zhang, Chun\|Wei, Qin\|Jiang, Tao\|Shou, Xi\|Li, Zhi-Qiang\|Wen, Hao
PMID:	24318994

68.
Journal:	Hepatobiliary Surg Nutr. 2015 Dec;4(6):426-35.
Title:	Detection of carcinogenic etheno-DNA adducts in children and adolescents with non-alcoholic steatohepatitis (NASH).
Author:	Teufel, Ulrike\|Peccerella, Teresa\|Engelmann, Guido\|Bruckner, Thomas\|Flechtenmacher, Christa\|Millonig, Gunda\|Stickel, Felix\|Hoffmann, Georg F\|Schirmacher, Peter\|Mueller, Sebastian\|Bartsch, Helmut\|Seitz, Helmut K
PMID:	26734629

69.
Journal:	Adv Pharmacol. 2015;74:85-111.
Title:	Polymorphic Variants of Cytochrome P450: Relevance to Cancer and Other Diseases.
Author:	Daly, Ann K
PMID:	26233904

70.
Journal:	Asian Pac J Cancer Prev. 2015;16(12):4803-12.
Title:	Molecular Links between Alcohol and Tobacco Induced DNA Damage, Gene Polymorphisms and Patho-physiological Consequences: A Systematic Review of Hepatic Carcinogenesis.
Author:	Mansoori, Abdul Anvesh\|Jain, Subodh Kumar
PMID:	26163595

71.
Journal:	Hepatobiliary Surg Nutr. 2015 Apr;4(2):117-23.
Title:	The generation of carcinogenic etheno-DNA adducts in the liver of patients with nonalcoholic fatty liver disease.
Author:	Linhart, Kirsten-Berit\|Glassen, Katharina\|Peccerella, Teresa\|Waldherr, Rudiger\|Linhart, Heinz\|Bartsch, Helmut\|Seitz, Helmut K
PMID:	26005678

72.
Journal:	Drug Metab Dispos. 2015 Jul;43(7):916-21.
Title:	Relative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult Mice.
Author:	Wang, Shuang\|Bott, Debbie\|Tung, Aveline\|Sugamori, Kim S\|Grant, Denis M
PMID:	25922528

73.
Journal:	Toxicol Sci. 2015 Apr;144(2):393-405.
Title:	N-hydroxylation of 4-aminobiphenyl by CYP2E1 produces oxidative stress in a mouse model of chemically induced liver cancer.
Author:	Wang, Shuang\|Sugamori, Kim S\|Tung, Aveline\|McPherson, J Peter\|Grant, Denis M
PMID:	25601990

74.
Journal:	Arch Biochem Biophys. 2015 Apr 15;572:81-88.
Title:	Dietary tomato powder inhibits alcohol-induced hepatic injury by suppressing cytochrome p450 2E1 induction in rodent models.
Author:	Stice, Camilla P\|Liu, Chun\|Aizawa, Koichi\|Greenberg, Andrew S\|Ausman, Lynne M\|Wang, Xiang-Dong
PMID:	25592162

75.
Journal:	Adv Exp Med Biol. 2015;815:361-73.
Title:	The effect of alcohol on Sirt1 expression and function in animal and human models of hepatocellular carcinoma (HCC).
Author:	Thompson, Kyle J\|Humphries, John R\|Niemeyer, David J\|Sindram, David\|McKillop, Iain H
PMID:	25427918

76.
Journal:	Pharmacogenet Genomics. 2015 Jan;25(1):1-7.
Title:	Copy number variability analysis of pharmacogenes in patients with lymphoma, leukemia, hepatocellular, and lung carcinoma using The Cancer Genome Atlas data.
Author:	Kim, In-Wha\|Han, Nayoung\|Kim, Myeong Gyu\|Kim, Therasa\|Oh, Jung Mi
PMID:	25379720

77.
Journal:	Biomed Res Int. 2015;2015:179867.
Title:	The effect of CYP, GST, and SULT polymorphisms and their interaction with smoking on the risk of hepatocellular carcinoma.
Author:	Boccia, Stefania\|Miele, Luca\|Panic, Nikola\|Turati, Federica\|Arzani, Dario\|Cefalo, Consuelo\|Amore, Rosarita\|Bulajic, Milutin\|Pompili, Maurizio\|Rapaccini, Gianlodovico\|Gasbarrini, Antonio\|La Vecchia, Carlo\|Grieco, Antonio
PMID:	25654087

78.
Journal:	Oncotarget. 2016 May 10;7(19):28612-23.
Title:	Changes in cytochrome P450s-mediated drug clearance in patients with hepatocellular carcinoma in vitro and in vivo: a bottom-up approach.
Author:	Gao, Jie\|Zhou, Jun\|He, Xiao-Pei\|Zhang, Yun-Fei\|Gao, Na\|Tian, Xin\|Fang, Yan\|Wen, Qiang\|Jia, Lin-Jing\|Jin, Han\|Qiao, Hai-Ling
PMID:	27086920

79.
Journal:	Int J Cancer. 2016 Sep 1;139(5):1171-81.
Title:	Tobacco carcinogen induces both lung cancer and non-alcoholic steatohepatitis and hepatocellular carcinomas in ferrets which can be attenuated by lycopene supplementation.
Author:	Aizawa, Koichi\|Liu, Chun\|Tang, Sanyuan\|Veeramachaneni, Sudipta\|Hu, Kang-Quan\|Smith, Donald E\|Wang, Xiang-Dong
PMID:	27116542

80.
Journal:	World J Gastroenterol. 2016 Apr 28;22(16):4091-108.
Title:	Adult mouse model of early hepatocellular carcinoma promoted by alcoholic liver disease.
Author:	Ambade, Aditya\|Satishchandran, Abhishek\|Gyongyosi, Benedek\|Lowe, Patrick\|Szabo, Gyongyi
PMID:	27122661

81.
Journal:	Oncotarget. 2016 Aug 2;7(31):50612-50623.
Title:	Significant change of cytochrome P450s activities in patients with hepatocellular carcinoma.
Author:	Zhou, Jun\|Wen, Qiang\|Li, Sai-Fei\|Zhang, Yun-Fei\|Gao, Na\|Tian, Xin\|Fang, Yan\|Gao, Jie\|Cui, Ming-Zhu\|He, Xiao-Pei\|Jia, Lin-Jing\|Jin, Han\|Qiao, Hai-Ling
PMID:	27203676

82.
Journal:	PLoS One. 2016 Nov 2;11(11):e0165457.
Title:	Integrated Multiple "-omics" Data Reveal Subtypes of Hepatocellular Carcinoma.
Author:	Liu, Gang\|Dong, Chuanpeng\|Liu, Lei
PMID:	27806083

83.
Journal:	Environ Pollut. 2017 Jun;225:610-619.
Title:	Altered cellular metabolism of HepG2 cells caused by microcystin-LR.
Author:	Ma, Junguo\|Feng, Yiyi\|Jiang, Siyu\|Li, Xiaoyu
PMID:	28336091

84.
Journal:	Oncotarget. 2017 Dec 5;8(68):112199-112210.
Title:	High CYP2E1 activity correlates with hepatofibrogenesis induced by nitrosamines.
Author:	Gao, Jie\|Wang, Gao-Ju\|Wang, Zhao\|Gao, Na\|Li, Jing\|Zhang, Yun-Fei\|Zhou, Jun\|Zhang, Hong-Xin\|Wen, Qiang\|Jin, Han\|Qiao, Hai-Ling
PMID:	29348818

85.
Journal:	Molecules. 2017 Sep 28;22(10). pii: molecules22101617.
Title:	A Network Pharmacology-Based Study on the Hepatoprotective Effect of Fructus Schisandrae.
Author:	Hong, Ming\|Zhang, Yongsheng\|Li, Sha\|Tan, Hor Yue\|Wang, Ning\|Mu, Shuzhen\|Hao, Xiaojiang\|Feng, Yibin
PMID:	28956809

86.
Journal:	J Hepatol. 2017 Aug;67(2):360-369.
Title:	Mice lacking liver-specific beta-catenin develop steatohepatitis and fibrosis after iron overload.
Author:	Preziosi, Morgan E\|Singh, Sucha\|Valore, Erika V\|Jung, Grace\|Popovic, Branimir\|Poddar, Minakshi\|Nagarajan, Shanmugam\|Ganz, Tomas\|Monga, Satdarshan P
PMID:	28341391

87.
Journal:	Int J Oncol. 2017 May;50(5):1832-1838.
Title:	Cytochrome P450 2E1 increases the sensitivity of hepatoma cells to vitamin K2.
Author:	Li, Lu\|Wang, Lu\|Song, Rui\|Chen, Guangliang\|Liu, Yanyan
PMID:	28339022

88.
Journal:	Drug Metab Pers Ther. 2017 Mar 1;32(1):59-65.
Title:	Cytotoxicity and cytochrome P450 inhibitory activities of Clinacanthus nutans.
Author:	Quah, Suk Yen\|Chin, Jin Han\|Akowuah, Gabriel Akyirem\|Khalivulla, Shaik Ibrahim\|Yeong, Siew Wei\|Sabu, Mandumpal Chacko
PMID:	28253196

89.
Journal:	Dig Liver Dis. 2017 Jan;49(1):77-83.
Title:	Meta-analysis of CYP2E1 polymorphisms in liver carcinogenesis.
Author:	Fu, Peiyao\|Yang, Fan\|Li, Bo\|Zhang, Biao\|Guan, Lianyue\|Sheng, Jiyao\|Ye, Yanshuo\|Wang, Zhanpeng\|Li, Peidong\|Xu, Li\|Zou, Liangjian\|Li, Wei
PMID:	27637154

90.
Journal:	J Pharmacol Exp Ther. 2018 May;365(2):398-407.
Title:	Higher CYP2E1 Activity Correlates with Hepatocarcinogenesis Induced by Diethylnitrosamine.
Author:	Gao, Jie\|Wang, Zhao\|Wang, Gao-Ju\|Zhang, Hong-Xin\|Gao, Na\|Wang, Jie\|Wang, Cai-E\|Chang, Zhao\|Fang, Yan\|Zhang, Yun-Fei\|Zhou, Jun\|Jin, Han\|Qiao, Hai-Ling
PMID:	29467309

91.
Journal:	Drug Chem Toxicol. 2018 May 3:1-8.
Title:	Augmentation of diethylnitrosamine-induced early stages of rat hepatocarcinogenesis by 1,2-dimethylhydrazine.
Author:	Punvittayagul, Charatda\|Chariyakornkul, Arpamas\|Chewonarin, Teera\|Jarukamjorn, Kanokwan\|Wongpoomchai, Rawiwan
PMID:	29722557

92.
Journal:	Cancer Manag Res. 2018 May 4;10:1037-1050.
Title:	Genetic variants of ALDH2-rs671 and CYP2E1-rs2031920 contributed to risk of hepatocellular carcinoma susceptibility in a Chinese population.
Author:	Ye, Xinping\|Wang, Xiangkun\|Shang, Liming\|Zhu, Guangzhi\|Su, Hao\|Han, Chuangye\|Qin, Wei\|Li, Guanghui\|Peng, Tao
PMID:	29765251

93.
Journal:	Mol Carcinog. 2018 Oct;57(10):1371-1382.
Title:	From hepatofibrosis to hepatocarcinogenesis: Higher cytochrome P450 2E1 activity is a potential risk factor.
Author:	Gao, Jie\|Wang, Zhao\|Wang, Gao-Ju\|Gao, Na\|Li, Jing\|Zhang, Yun-Fei\|Zhou, Jun\|Zhang, Hong-Xin\|Wen, Qiang\|Jin, Han\|Qiao, Hai-Ling
PMID:	29917271

94.
Journal:	Drug Metab Lett. 2018 Jul 9. pii: DML-EPUB-91604.
Title:	Genistein affects expression of cytochrome P450 (CYP450) genes in hepatocellular carcinoma (HEPG2/C3A) cell line.
Author:	Lepri, Sandra Regina\|Sartori, Daniele\|Semprebon, Simone Cristine\|Baranoski, Adrivanio\|Coatti, Giuliana Castello\|Mantovani, Mario Sergio
PMID:	29984664

95.
Journal:	J Med Food. 2018 Sep;21(9):866-875.
Title:	Black Radish (Raphanus sativus L. var. niger) Extract Mediates Its Hepatoprotective Effect on Carbon Tetrachloride-Induced Hepatic Injury by Attenuating Oxidative Stress.
Author:	Ahn, Meejung\|Kim, Jeongtae\|Hong, Seunghyun\|Kim, Jungeun\|Ko, Hana\|Lee, Nam-Ho\|Kim, Gi-Ok\|Shin, Taekyun
PMID:	30067118

96.
Journal:	Biomed Res Int. 2018 Jul 25;2018:5859415.
Title:	Downregulation of CYP2A6 and CYP2C8 in Tumor Tissues Is Linked to Worse Overall Survival and Recurrence-Free Survival from Hepatocellular Carcinoma.
Author:	Ren, Xiaojing\|Ji, Yuanyuan\|Jiang, Xuhua\|Qi, Xun
PMID:	30148168

97.
Journal:	Cytokine. 2018 Oct 27. pii: S1043-4666(18)30402-2.
Title:	STAT5 deficiency in hepatocytes reduces diethylnitrosamine-induced liver tumorigenesis in mice.
Author:	Kaltenecker, Doris\|Themanns, Madeleine\|Mueller, Kristina M\|Spirk, Katrin\|Golob-Schwarzl, Nicole\|Friedbichler, Katrin\|Kenner, Lukas\|Haybaeck, Johannes\|Moriggl, Richard
PMID:	30377054