Primary Site >> Esophagus Cancer

Gene >> CYP2E1

Journal: Pharmacol Ther. 1996;71(1-2):57-81.
Title: N-nitrosodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation.
Author: Verna, L|Whysner, J|Williams, G M
PMID: 8910949
Journal: Alcohol Clin Exp Res. 1996 Sep;20(6):1033-7.
Title: Cytochromes P4502E1 and P4501A1 genotypes and susceptibility to cirrhosis or upper aerodigestive tract cancer in alcoholic caucasians.
Author: Lucas, D|Menez, C|Floch, F|Gourlaouen, Y|Sparfel, O|Joannet, I|Bodenez, P|Jezequel, J|Gouerou, H|Berthou, F|Bardou, L G|Menez, J F
PMID: 8892524
Journal: Int J Cancer. 1997 Apr 10;71(2):192-5.
Title: CYP1A1, CYP2E1 and GSTM1 polymorphisms are not associated with susceptibility to squamous-cell carcinoma of the esophagus.
Author: Morita, S|Yano, M|Shiozaki, H|Tsujinaka, T|Ebisui, C|Morimoto, T|Kishibuti, M|Fujita, J|Ogawa, A|Taniguchi, M|Inoue, M|Tamura, S|Yamazaki, K|Kikkawa, N|Mizunoya, S|Monden, M
PMID: 9139841
Journal: J Clin Gastroenterol. 1997 Dec;25(4):568-75.
Title: Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and human esophageal squamous cell carcinoma susceptibility.
Author: Hori, H|Kawano, T|Endo, M|Yuasa, Y
PMID: 9451664
Journal: Cancer Epidemiol Biomarkers Prev. 1998 Nov;7(11):1013-8.
Title: Susceptibility to esophageal cancer and genetic polymorphisms in glutathione S-transferases T1, P1, and M1 and cytochrome P450 2E1.
Author: Lin, D X|Tang, Y M|Peng, Q|Lu, S X|Ambrosone, C B|Kadlubar, F F
PMID: 9829710
Journal: Zhonghua Zhong Liu Za Zhi. 1998 Mar;20(2):94-7.
Title: [Genetic polymorphisms of cytochrome P450 2E1 and glutathione S-transferase P1 and susceptibility to esophageal cancer].
Author: Lin, D|Tang, Y|Peng, Q
PMID: 10920953
Journal: Cancer Res. 1999 Jan 1;59(1):91-8.
Title: Depentylation of [3H-pentyl]methyl-n-amylnitrosamine by rat esophageal and liver microsomes and by rat and human cytochrome P450 isoforms.
Author: Chen, S C|Wang, X|Xu, G|Zhou, L|Vennerstrom, J L|Gonzalez, F|Gelboin, H V|Mirvish, S S
PMID: 9892192
Journal: J Toxicol Environ Health A. 1999 Dec 10;58(7):397-411.
Title: Metabolism of N-nitrosobenzylmethylamine by human cytochrome P-450 enzymes.
Author: Morse, M A|Lu, J|Stoner, G D|Murphy, S E|Peterson, L A
PMID: 10616189
Journal: Cancer Lett. 2000 Aug 1;156(1):73-81.
Title: Association between GSTM1*0 and squamous dysplasia of the esophagus in the high risk region of Linxian, China.
Author: Roth, M J|Dawsey, S M|Wang, G|Tangrea, J A|Zhou, B|Ratnasinghe, D|Woodson, K G|Olivero, O A|Poirier, M C|Frye, B L|Taylor, P R|Weston, A
PMID: 10840162
Journal: Cancer Epidemiol Biomarkers Prev. 2000 Jun;9(6):551-6.
Title: Impact of genetic polymorphisms in cytochrome P450 2E1 and glutathione S-transferases M1, T1, and P1 on susceptibility to esophageal cancer among high-risk individuals in China.
Author: Tan, W|Song, N|Wang, G Q|Liu, Q|Tang, H J|Kadlubar, F F|Lin, D X
PMID: 10868687
Journal: Cancer Epidemiol Biomarkers Prev. 2000 Jul;9(7):675-80.
Title: Cytochrome P450 2E1 polymorphism in gastric cancer in Brazil: case-control studies of Japanese Brazilians and non-Japanese Brazilians.
Author: Nishimoto, I N|Hanaoka, T|Sugimura, H|Nagura, K|Ihara, M|Li, X J|Arai, T|Hamada, G S|Kowalski, L P|Tsugane, S
PMID: 10919737
Journal: Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2001 Feb;18(1):62-5.
Title: [Progress in researches on the relationship between genetic polymorphisms of alcohol-metabolizing enzymes and cancers].
Author: Zhang, Z|Bian, J
PMID: 11172647
Journal: Zhonghua Zhong Liu Za Zhi. 2001 Nov;23(6):473-6.
Title: [Detection of malondialdehyde-DNA adduct level by 32P-postlabeling assay in normal human esophageal epithelium and esophageal squamous cell carcinoma].
Author: Xing, D|Song, N|Tan, W
PMID: 11859713
Journal: Sci China C Life Sci. 2001 Aug;44(4):356-64.
Title: Expression of cytochrome P4502E1 in human liver: Relationship between genotype and phenotype in Chinese.
Author: Tan, W|Wu, J|Tang, H|Lin, D
PMID: 18726416
Journal: Cancer Epidemiol Biomarkers Prev. 2002 Jan;11(1):29-34.
Title: Interaction between cytochrome P-450 2E1 polymorphisms and environmental factors with risk of esophageal and stomach cancers in Chinese.
Author: Gao, Changming|Takezaki, Toshiro|Wu, Jianzhong|Li, Zhongyou|Wang, Jiandong|Ding, Jianhua|Liu, Yanting|Hu, Xu|Xu, Tianliang|Tajima, Kazuo|Sugimura, Haruhiko
PMID: 11815398
Journal: Alcohol Clin Exp Res. 2002 Aug;26(8 Suppl):15S-19S.
Title: Tandem repeat polymorphism of the CYP2E1 gene: an association study with esophageal cancer and lung cancer.
Author: Itoga, Sakae|Nomura, Fumio|Makino, Yasuhiko|Tomonaga, Takeshi|Shimada, Hideaki|Ochiai, Takenori|Iizasa, Toshihiko|Baba, Masayuki|Fujisawa, Takehiko|Harada, Shoji
PMID: 12198369
Journal: Mutat Res. 2003 Nov;544(2-3):365-73.
Title: Mechanisms of esophageal cancer development in Brazilians.
Author: Ribeiro Pinto, Luis Felipe|Teixeira Rossini, Ana Maria|Albano, Rodolpho Mattos|Felzenszwalb, Israel|de Moura Gallo, Claudia Victoria|Nunes, Rodolfo Acatuassu|Andreollo, Nelson Adami
PMID: 14644339
Journal: Oncol Rep. 2003 Sep-Oct;10(5):1615-23.
Title: Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review).
Author: Xing, Deyin|Tan, Wen|Lin, Dongxin
PMID: 12883749
Journal: Alcohol Clin Exp Res. 2003 Aug;27(8 Suppl):42S-46S.
Title: Transcriptional activity of the tandem repeat polymorphism in the 5'-flanking region of the human CYP2E1 gene.
Author: Nomura, Fumio|Itoga, Sakae|Uchimoto, Takayuki|Tomonaga, Takeshi|Nezu, Masahiko|Shimada, Hideaki|Ochiai, Takenori
PMID: 12960506
Journal: Cancer Lett. 2004 Sep 30;213(2):195-202.
Title: Genetic polymorphisms in three Iranian populations with different risks of esophageal cancer, an ecologic comparison.
Author: Sepehr, Alireza|Kamangar, Farin|Abnet, Christian C|Fahimi, Saman|Pourshams, Akram|Poustchi, Hossein|Zeinali, Sirous|Sotoudeh, Masood|Islami, Farhad|Nasrollahzadeh, Dariush|Malekzadeh, Reza|Taylor, Philip R|Dawsey, Sanford M
PMID: 15327835
Journal: World J Gastroenterol. 2005 May 7;11(17):2531-8.
Title: Phase I/II enzyme gene polymorphisms and esophageal cancer risk: a meta-analysis of the literature.
Author: Yang, Chun-Xia|Matsuo, Keitaro|Wang, Zhi-Ming|Tajima, Kazuo
PMID: 15849806
Journal: World J Gastroenterol. 2005 Jun 28;11(24):3651-4.
Title: Relationship between genetic polymorphisms of metabolizing enzymes CYP2E1, GSTM1 and Kazakh's esophageal squamous cell cancer in Xinjiang, China.
Author: Lu, Xiao-Mei|Zhang, Yue-Ming|Lin, Ren-Yong|Arzi, Gul|Wang, Xing|Zhang, Ya-Lou|Zhang, Yan|Wang, Yan|Wen, Hao
PMID: 15968714
Journal: Asian Pac J Cancer Prev. 2005 Jul-Sep;6(3):256-62.
Title: Esophageal cancer risk by ALDH2 and ADH2 polymorphisms and alcohol consumption: exploration of gene-environment and gene-gene interactions.
Author: Yang, Chun-Xia|Matsuo, Keitaro|Ito, Hidemi|Hirose, Kaoru|Wakai, Kenji|Saito, Toshiko|Shinoda, Masayuki|Hatooka, Shunzo|Mizutani, Kazuko|Tajima, Kazuo
PMID: 16235983
Journal: J Hum Genet. 2006;51(2):104-11. Epub 2005 Dec 20.
Title: ALDH2 and CYP2E1 genotypes, urinary acetaldehyde excretion and the health consequences in moderate alcohol consumers.
Author: Yamada, Yuichi|Imai, Tsunehiko|Ishizaki, Masao|Honda, Ryumon
PMID: 16365683
Journal: J Gastroenterol Hepatol. 2006 May;21(5):805-13.
Title: Effect of chronic dietary ethanol in the promotion of N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats.
Author: Tsutsumi, Mikihiro|George, Joseph|Ishizawa, Kiyohiro|Fukumura, Atushi|Takase, Shujiro
PMID: 16704527
Journal: Carcinogenesis. 2007 Dec;28(12):2537-42. Epub 2007 Oct 4.
Title: Polymorphisms of GSTP1 and GSTT1, but not of CYP2A6, CYP2E1 or GSTM1, modify the risk for esophageal cancer in a western population.
Author: Rossini, A|Rapozo, D C M|Soares Lima, S C|Guimaraes, D P|Ferreira, M A|Teixeira, R|Kruel, C D P|Barros, S G S|Andreollo, N A|Acatauassu, R|Matos, H J|Albano, R M|Pinto, L F Ribeiro
PMID: 17916905
Journal: Int J Cancer. 2007 Oct 15;121(8):1643-58.
Title: Genetic polymorphisms and esophageal cancer risk.
Author: Hiyama, Toru|Yoshihara, Masaharu|Tanaka, Shinji|Chayama, Kazuaki
PMID: 17674367
Journal: World J Gastroenterol. 2008 Mar 7;14(9):1444-9.
Title: Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males.
Author: Guo, Yan-Mei|Wang, Qin|Liu, Yan-Zhen|Chen, Huei-Min|Qi, Zhi|Guo, Qing-Hong
PMID: 18322963
Journal: Nutr Cancer. 2010;62(6):734-42.
Title: Association of xenobiotic metabolizing enzymes genetic polymorphisms with esophageal cancer in Kashmir Valley and influence of environmental factors.
Author: Malik, Manzoor Ahmad|Upadhyay, Rohit|Mittal, Rama Devi|Zargar, Showket Ali|Mittal, Balraj
PMID: 20661821
Journal: Med Oncol. 2011 Mar;28(1):182-7.
Title: CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls.
Author: Niu, Yuming|Yuan, Hua|Leng, Weidong|Pang, Yongchu|Gu, Ning|Chen, Ning
PMID: 20195803
Journal: Int J Cancer. 2011 Feb 1;128(3):533-40.
Title: Ethanol-mediated carcinogenesis in the human esophagus implicates CYP2E1 induction and the generation of carcinogenic DNA-lesions.
Author: Millonig, Gunda|Wang, Ying|Homann, Nils|Bernhardt, Friederike|Qin, Hua|Mueller, Sebastian|Bartsch, Helmut|Seitz, Helmut K
PMID: 20715111
Journal: BMC Gastroenterol. 2011 Jun 14;11:74.
Title: Multi-susceptibility genes associated with the risk of the development stages of esophageal squamous cell cancer in Feicheng County.
Author: Li, Qing Da|Li, Hao|Wang, Mei Shu|Diao, Tao Yu|Zhou, Zhi Ying|Fang, Qiang Xue|Yang, Fang Yan|Li, Qing Hui
PMID: 21672255
Journal: Cancer Epidemiol. 2012 Jun;36(3):276-82.
Title: Associations between CYP1A1 and CYP2E1 polymorphisms and susceptibility to esophageal cancer in Chaoshan and Taihang areas of China.
Author: Wang, Dianliang|Su, Min|Tian, Dongping|Liang, Shuang|Zhang, Jing
PMID: 22088806
Journal: Integr Biol (Camb). 2012 Sep;4(9):1122-9.
Title: Tolfenamic acid suppresses cytochrome P450 2E1 expression in mouse liver.
Author: Shukoor, Mohammed I|Tiwari, Samata|Sankpal, Umesh T|Maliakal, Pius|Connelly, Sarah F|Siddiqi, Shaila|Siddiqi, Shadab A|Basha, Riyaz
PMID: 22832660
Journal: Exp Ther Med. 2012 Nov;4(5):938-948. Epub 2012 Aug 28.
Title: Cytochrome P450 2E1 RsaI/PstI polymorphism and risk of esophageal cancer: A meta-analysis of 17 case-control studies.
Author: Leng, Wei-Dong|Zeng, Xian-Tao|Chen, Yong-Ji|Duan, Xiao-Li|Niu, Yu-Ming|Long, Rong-Pei|Luo, Zhi-Xiao
PMID: 23226753
Journal: J Hum Genet. 2013 Nov;58(11):742-8.
Title: Polymorphisms in alcohol-metabolizing enzymes and esophageal carcinoma susceptibility: a Dutch Caucasian case-control study.
Author: Dura, Polat|Berkers, Tineke|van Veen, Elke M|Salomon, Jody|te Morsche, Rene H M|Roelofs, Hennie M J|Kristinsson, Jon O|Wobbes, Theo|Witteman, Ben J M|Tan, Adriaan C I T L|Drenth, Joost P H|Peters, Wilbert H M
PMID: 24048263