Primary Site >> Esophagus Cancer
Gene >> CYP2E1
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Ref: Cytochromes P4502E1 and P4501A1 genotypes and susceptibility to cirrhosis or upper aerodigestive tract cancer in alcoholic caucasians. PMID: 8892524 Ref: N-nitrosodiethylamine mechanistic data and risk assessment: bioactivation, DNA-adduct formation, mutagenicity, and tumor initiation. PMID: 8910949 |
Ref: CYP1A1, CYP2E1 and GSTM1 polymorphisms are not associated with susceptibility to squamous-cell carcinoma of the esophagus. PMID: 9139841 Ref: Genetic polymorphisms of tobacco- and alcohol-related metabolizing enzymes and human esophageal squamous cell carcinoma susceptibility. PMID: 9451664 |
Ref: Susceptibility to esophageal cancer and genetic polymorphisms in glutathione S-transferases T1, P1, and M1 and cytochrome P450 2E1. PMID: 9829710 Ref: [Genetic polymorphisms of cytochrome P450 2E1 and glutathione S-transferase P1 and susceptibility to esophageal cancer]. PMID: 10920953 |
Ref: Depentylation of [3H-pentyl]methyl-n-amylnitrosamine by rat esophageal and liver microsomes and by rat and human cytochrome P450 isoforms. PMID: 9892192 Ref: Metabolism of N-nitrosobenzylmethylamine by human cytochrome P-450 enzymes. PMID: 10616189 |
Ref: Association between GSTM1*0 and squamous dysplasia of the esophagus in the high risk region of Linxian, China. PMID: 10840162 Ref: Impact of genetic polymorphisms in cytochrome P450 2E1 and glutathione S-transferases M1, T1, and P1 on susceptibility to esophageal cancer among high-risk individuals in China. PMID: 10868687 Ref: Cytochrome P450 2E1 polymorphism in gastric cancer in Brazil: case-control studies of Japanese Brazilians and non-Japanese Brazilians. PMID: 10919737 |
Ref: [Progress in researches on the relationship between genetic polymorphisms of alcohol-metabolizing enzymes and cancers]. PMID: 11172647 Ref: [Detection of malondialdehyde-DNA adduct level by 32P-postlabeling assay in normal human esophageal epithelium and esophageal squamous cell carcinoma]. PMID: 11859713 Ref: Expression of cytochrome P4502E1 in human liver: Relationship between genotype and phenotype in Chinese. PMID: 18726416 |
Ref: Interaction between cytochrome P-450 2E1 polymorphisms and environmental factors with risk of esophageal and stomach cancers in Chinese. PMID: 11815398 Ref: Tandem repeat polymorphism of the CYP2E1 gene: an association study with esophageal cancer and lung cancer. PMID: 12198369 |
Ref: Genetic polymorphisms and susceptibility to esophageal cancer among Chinese population (review). PMID: 12883749 Ref: Transcriptional activity of the tandem repeat polymorphism in the 5'-flanking region of the human CYP2E1 gene. PMID: 12960506 Ref: Mechanisms of esophageal cancer development in Brazilians. PMID: 14644339 |
Ref: Genetic polymorphisms in three Iranian populations with different risks of esophageal cancer, an ecologic comparison. PMID: 15327835 |
Ref: Phase I/II enzyme gene polymorphisms and esophageal cancer risk: a meta-analysis of the literature. PMID: 15849806 Ref: Relationship between genetic polymorphisms of metabolizing enzymes CYP2E1, GSTM1 and Kazakh's esophageal squamous cell cancer in Xinjiang, China. PMID: 15968714 Ref: Esophageal cancer risk by ALDH2 and ADH2 polymorphisms and alcohol consumption: exploration of gene-environment and gene-gene interactions. PMID: 16235983 |
Ref: ALDH2 and CYP2E1 genotypes, urinary acetaldehyde excretion and the health consequences in moderate alcohol consumers. PMID: 16365683 Ref: Effect of chronic dietary ethanol in the promotion of N-nitrosomethylbenzylamine-induced esophageal carcinogenesis in rats. PMID: 16704527 |
Ref: Genetic polymorphisms and esophageal cancer risk. PMID: 17674367 Ref: Polymorphisms of GSTP1 and GSTT1, but not of CYP2A6, CYP2E1 or GSTM1, modify the risk for esophageal cancer in a western population. PMID: 17916905 |
Ref: Genetic polymorphisms in cytochrome P4502E1, alcohol and aldehyde dehydrogenases and the risk of esophageal squamous cell carcinoma in Gansu Chinese males. PMID: 18322963 |
Ref: Association of xenobiotic metabolizing enzymes genetic polymorphisms with esophageal cancer in Kashmir Valley and influence of environmental factors. PMID: 20661821 |
Ref: CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls. PMID: 20195803 Ref: Ethanol-mediated carcinogenesis in the human esophagus implicates CYP2E1 induction and the generation of carcinogenic DNA-lesions. PMID: 20715111 Ref: Multi-susceptibility genes associated with the risk of the development stages of esophageal squamous cell cancer in Feicheng County. PMID: 21672255 |
Ref: Associations between CYP1A1 and CYP2E1 polymorphisms and susceptibility to esophageal cancer in Chaoshan and Taihang areas of China. PMID: 22088806 Ref: Tolfenamic acid suppresses cytochrome P450 2E1 expression in mouse liver. PMID: 22832660 Ref: Cytochrome P450 2E1 RsaI/PstI polymorphism and risk of esophageal cancer: A meta-analysis of 17 case-control studies. PMID: 23226753 |
Ref: Polymorphisms in alcohol-metabolizing enzymes and esophageal carcinoma susceptibility: a Dutch Caucasian case-control study. PMID: 24048263 |