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Gene >> CYP2E1

Journal: Carcinogenesis. 1994 Jan;15(1):73-8.
Title: Induction of cyp2e-1 protein in mouse colon.
Author: Rosenberg, D W|Mankowski, D C
PMID: 8293551
Journal: Biochem Pharmacol. 1996 Jan 12;51(1):61-9.
Title: Effects of diet and ethanol on the expression and localization of cytochromes P450 2E1 and P450 2C7 in the colon of male rats.
Author: Hakkak, R|Korourian, S|Ronis, M J|Ingelman-Sundberg, M|Badger, T M
PMID: 8534269
Journal: Int J Oncol. 1996 Sep;9(3):427-31.
Title: Effect of cytochrome P450 inducers on expression of oncogenes and a tumor suppressor gene in human colon cancer cells.
Author: Vasquez, H|Strobel, H
PMID: 21541530
Journal: Drug Metab Dispos. 1996 Apr;24(4):408-13.
Title: A comparative study of hepatic and colonic metabolic enzymes in inbred mouse lines before and after treatment with the colon carcinogen, 1,2-dimethylhydrazine.
Author: Delker, D A|Bammler, T K|Rosenberg, D W
PMID: 8801055
Journal: Proc Soc Exp Biol Med. 1998 Jan;217(1):104-8.
Title: Effect of tea extracts, polyphenols, and epigallocatechin gallate on azoxymethane-induced colon cancer.
Author: Weisburger, J H|Rivenson, A|Aliaga, C|Reinhardt, J|Kelloff, G J|Boone, C W|Steele, V E|Balentine, D A|Pittman, B|Zang, E
PMID: 9421213
Journal: Biochem Pharmacol. 1999 Apr 15;57(8):951-4.
Title: Decrease in hepatic cytochrome P450 after interleukin-2 immunotherapy.
Author: Elkahwaji, J|Robin, M A|Berson, A|Tinel, M|Letteron, P|Labbe, G|Beaune, P|Elias, D|Rougier, P|Escudier, B|Duvillard, P|Pessayre, D
PMID: 10086330
Journal: Eur J Cancer Prev. 1999 Jul;8(3):207-11.
Title: Meat, metabolic genotypes and risk for colorectal cancer.
Author: Roberts-Thomson, I C|Butler, W J|Ryan, P
PMID: 10443949
Journal: Anticancer Res. 2000 Jan-Feb;20(1B):519-22.
Title: Colorectal cancer risk in relation to genetic polymorphism of cytochrome P450 1A1, 2E1, and glutathione-S-transferase M1 enzymes.
Author: Kiss, I|Sandor, J|Pajkos, G|Bogner, B|Hegedus, G|Ember, I
PMID: 10769717
Journal: J Gastroenterol Hepatol. 2001 Jun;16(6):631-5.
Title: Metabolic genotypes and risk for colorectal cancer.
Author: Butler, W J|Ryan, P|Roberts-Thomson, I C
PMID: 11422615
Journal: Mutat Res. 2001 Aug 22;495(1-2):103-15.
Title: Host determinants of DNA alkylation and DNA repair activity in human colorectal tissue: O(6)-methylguanine levels are associated with GSTT1 genotype and O(6)-alkylguanine-DNA alkyltransferase activity with CYP2D6 genotype.
Author: Povey, A C|Hall, C N|Badawi, A F|Cooper, D P|Guppy, M J|Jackson, P E|O'Connor, P J|Margison, G P
PMID: 11448648
Journal: Nutr Cancer. 2001;39(2):252-8.
Title: Effect of grape seed proanthocyanidins on colon aberrant crypts and breast tumors in a rat dual-organ tumor model.
Author: Singletary, K W|Meline, B
PMID: 11759289
Journal: Carcinogenesis. 2002 Jul;23(7):1235-41.
Title: Hemizygous mice for the angiotensin II type 2 receptor gene have attenuated susceptibility to azoxymethane-induced colon tumorigenesis.
Author: Takagi, Tetsuo|Nakano, Yuichiro|Takekoshi, Susumu|Inagami, Tadashi|Tamura, Masaaki
PMID: 12117783
Journal: Cancer Epidemiol Biomarkers Prev. 2002 Oct;11(10 Pt 1):1019-24.
Title: Red meat intake, CYP2E1 genetic polymorphisms, and colorectal cancer risk.
Author: Le Marchand, Loic|Donlon, Timothy|Seifried, Ann|Wilkens, Lynne R
PMID: 12376502
Journal: Zhonghua Yu Fang Yi Xue Za Zhi. 2004 May;38(3):162-6.
Title: [Genetic polymorphism in cytochrome P450 2E1, salted food and colorectal cancer susceptibility: a case-control study].
Author: Yu, Wei-ping|Chen, Kun|Ma, Xin-yuan|Yao, Kai-yan|Jiang, Qin-ting|Zou, Yan|Zhou, Hai-guang
PMID: 15182482
Journal: Pharmacogenet Genomics. 2005 Aug;15(8):535-46.
Title: A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer.
Author: Landi, Stefano|Gemignani, Federica|Moreno, Victor|Gioia-Patricola, Lydie|Chabrier, Amelie|Guino, Elisabeth|Navarro, Matilde|de Oca, Javier|Capella, Gabriel|Canzian, Federico
PMID: 16006997
Journal: Dig Dis. 2005;23(3-4):297-303.
Title: Alcohol consumption and cancer of the gastrointestinal tract.
Author: Seitz, Helmut K|Maurer, Britta|Stickel, Felix
PMID: 16508294
Journal: Zhonghua Liu Xing Bing Xue Za Zhi. 2005 Sep;26(9):659-64.
Title: [A case-control study on the association between genetic polymorphisms of metabolic enzymes and the risk of colorectal cancer].
Author: Chen, Kun|Jin, Ming-juan|Fan, Chun-hong|Song, Liang|Jiang, Qin-ting|Yu, Wei-ping|Ma, Xin-yuan|Yao, Kai-yan
PMID: 16471212
Journal: Food Chem Toxicol. 2005 Dec;43(12):1753-62.
Title: Modulation of cytochrome P450 enzymes by organosulfur compounds from garlic.
Author: Davenport, Destiny M|Wargovich, Michael J
PMID: 16000231
Journal: Mutat Res. 2006 Jan 29;593(1-2):39-49. Epub 2005 Jul 21.
Title: Role of epoxide hydrolase, NAD(P)H:quinone oxidoreductase, cytochrome P450 2E1 or alcohol dehydrogenase genotypes in susceptibility to colorectal cancer.
Author: van der Logt, Elise M J|Bergevoet, Saskia M|Roelofs, Hennie M J|Te Morsche, Rene H M|Dijk, Yvo van|Wobbes, Theo|Nagengast, Fokko M|Peters, Wilbert H M
PMID: 16039674
Journal: Carcinogenesis. 2006 Feb;27(2):287-92. Epub 2005 Aug 19.
Title: Effects of indole-3-carbinol and phenethyl isothiocyanate on colon carcinogenesis induced by azoxymethane in rats.
Author: Plate, Andrea Y A|Gallaher, Daniel D
PMID: 16113056
Journal: J Nutr. 2006 Mar;136(3 Suppl):832S-834S.
Title: Diallylsulfide and allylmethylsulfide are uniquely effective among organosulfur compounds in inhibiting CYP2E1 protein in animal models.
Author: Wargovich, Michael J
PMID: 16484575
Journal: Br J Nutr. 2006 Oct;96(4):609-19.
Title: Genetic polymorphism of xenobiotic metabolising enzymes, diet and cancer susceptibility.
Author: Reszka, Edyta|Wasowicz, Wojciech|Gromadzinska, Jolanta
PMID: 17010218
Journal: Alcohol Clin Exp Res. 2007 Jan;31(1 Suppl):S72-6.
Title: Effect of chronic dietary ethanol consumption on colonic cancer in rats induced by 1,1-dimethylhydrazine.
Author: Hayashi, Nobuhiko|Tsutsumi, Mikihiro|Fukura, Masayuki|Yano, Hirokazu|Tsuchishima, Mutsumi|Takase, Shujiro
PMID: 17331170
Journal: BMC Cancer. 2007 Jun 30;7:115.
Title: Case-only study of interactions between metabolic enzymes and smoking in colorectal cancer.
Author: Fan, Chunhong|Jin, Mingjuan|Chen, Kun|Zhang, Yongjing|Zhang, Shuangshuang|Liu, Bing
PMID: 17603900
Journal: Cancer Epidemiol Biomarkers Prev. 2007 Jul;16(7):1460-7.
Title: Combinations of cytochrome P450 gene polymorphisms enhancing the risk for sporadic colorectal cancer related to red meat consumption.
Author: Kury, Sebastien|Buecher, Bruno|Robiou-du-Pont, Sebastien|Scoul, Catherine|Sebille, Veronique|Colman, Helene|Le Houerou, Claire|Le Neel, Tanguy|Bourdon, Jeremie|Faroux, Roger|Ollivry, Jean|Lafraise, Bernard|Chupin, Louis-Dominique|Bezieau, Stephane
PMID: 17627011
Journal: Anticancer Res. 2007 Jul-Aug;27(4C):2931-7.
Title: Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary.
Author: Kiss, Istvan|Orsos, Zsuzsa|Gombos, Katalin|Bogner, Barna|Csejtei, Andras|Tibold, Antal|Varga, Zsuzsa|Pazsit, Emese|Magda, Ingrid|Zolyomi, Annamaria|Ember, Istvan
PMID: 17695473
Journal: World J Gastroenterol. 2007 Nov 21;13(43):5725-30.
Title: CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking.
Author: Gao, Chang-Ming|Takezaki, Toshiro|Wu, Jian-Zhong|Chen, Min-Bin|Liu, Yan-Ting|Ding, Jian-Hua|Sugimura, Haruhiko|Cao, Jia|Hamajima, Nobuyuki|Tajima, Kazuo
PMID: 17963298
Journal: Cancer Epidemiol Biomarkers Prev. 2008 Jul;17(7):1800-7.
Title: Genetic polymorphisms of CYP2E1 and risk of colorectal adenomas in the Self Defense Forces Health Study.
Author: Morita, Makiko|Tabata, Shinji|Tajima, Osamu|Yin, Guang|Abe, Hiroshi|Kono, Suminori
PMID: 18628434
Journal: Mol Carcinog. 2008 Sep;47(9):667-77.
Title: Development of aberrant crypt foci in the colons of ob/ob and db/db mice: evidence that leptin is not a promoter.
Author: Ealey, Kafi N|Lu, Suying|Archer, Michael C
PMID: 18240295
Journal: J Nutr. 2008 Mar;138(3):526-32.
Title: Cruciferous vegetables reduce morphological markers of colon cancer risk in dimethylhydrazine-treated rats.
Author: Arikawa, Andrea Y|Gallaher, Daniel D
PMID: 18287361
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):235-41.
Title: Genetic polymorphisms of CYP2E1 and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study.
Author: Morita, Makiko|Le Marchand, Loic|Kono, Suminori|Yin, Guang|Toyomura, Kengo|Nagano, Jun|Mizoue, Tetsuya|Mibu, Ryuichi|Tanaka, Masao|Kakeji, Yoshihiro|Maehara, Yoshihiko|Okamura, Takeshi|Ikejiri, Koji|Futami, Kitaroh|Maekawa, Takafumi|Yasunami, Yohichi|Take
PMID: 19124503
Journal: Cancer Biol Ther. 2009 Jul;8(14):1313-7. Epub 2009 Jul 11.
Title: The signal pathways in azoxymethane-induced colon cancer and preventive implications.
Author: Chen, Jiezhong|Huang, Xu-Feng
PMID: 19502780
Journal: Cancer Epidemiol Biomarkers Prev. 2009 Sep;18(9):2522-7.
Title: A novel polymorphism rs1329149 of CYP2E1 and a known polymorphism rs671 of ALDH2 of alcohol metabolizing enzymes are associated with colorectal cancer in a southwestern Chinese population.
Author: Yang, Huan|Zhou, Yanhong|Zhou, Ziyuan|Liu, Jinyi|Yuan, Xiaoyan|Matsuo, Ketaro|Takezaki, Toshiro|Tajima, Kazuo|Cao, Jia
PMID: 19706845
Journal: World J Gastroenterol. 2010 Jun 21;16(23):2949-53.
Title: CYP2E1 PstI/RsaI polymorphism and colorectal cancer risk: a meta-analysis.
Author: Zhou, Guo-Wu|Hu, Jia|Li, Qiang
PMID: 20556843
Journal: Neuro Endocrinol Lett. 2011;32 Suppl 1:8-14.
Title: Effects of Lactobacillus casei on the expression and the activity of cytochromes P450 and on the CYP mRNA level in the intestine and the liver of male rats.
Author: Matuskova, Zuzana|Siller, Michal|Tunkova, Alena|Anzenbacherova, Eva|Zacharova, Alice|Tlaskalova-Hogenova, Helena|Zidek, Zdenek|Anzenbacher, Pavel
PMID: 22167211
Journal: Hum Genomics. 2011 Oct;5(6):530-7.
Title: Role of CYP2E1 genotypes in susceptibility to colorectal cancer in the Kashmiri population.
Author: Sameer, A Syed|Nissar, Saniya|Qadri, Qurteeba|Alam, Shafia|Baba, Shahid Mudasir|Siddiqi, Mushtaq A
PMID: 22155602
Journal: Genet Test Mol Biomarkers. 2011 Jun;15(6):423-9.
Title: CYP1A1, CYP2E1, and GSTM1 gene polymorphisms and susceptibility to colorectal and gastric cancer among Lebanese.
Author: Darazy, Mohamad|Balbaa, Mahmoud|Mugharbil, Anas|Saeed, Hesham|Sidani, Hassan|Abdel-Razzak, Ziad
PMID: 21385088
Journal: Int J Cancer. 2012 Apr 15;130(8):1898-907.
Title: Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk.
Author: Wang, Jun|Joshi, Amit D|Corral, Roman|Siegmund, Kimberly D|Marchand, Loic Le|Martinez, Maria Elena|Haile, Robert W|Ahnen, Dennis J|Sandler, Robert S|Lance, Peter|Stern, Mariana C
PMID: 21618522
Journal: Pathol Oncol Res. 2012 Jul;18(3):651-6.
Title: Association of GSTM1, GSTT1, GSTP1 and CYP2E1 single nucleotide polymorphisms with colorectal cancer in Iran.
Author: Ebrahimkhani, Saeideh|Asgharian, Ali Mohammad|Nourinaier, Babak|Ebrahimkhani, Khadijeh|Vali, Nasrin|Abbasi, Fatemeh|Zali, Mohammad Reza
PMID: 22228187
Journal: Dig Dis Sci. 2012 Jul;57(7):1866-74.
Title: High-fat diet alters gene expression in the liver and colon: links to increased development of aberrant crypt foci.
Author: Padidar, Sara|Farquharson, Andrew J|Williams, Lynda M|Kearney, Rebecca|Arthur, John R|Drew, Janice E
PMID: 22373862
Journal: Carcinogenesis. 2012 Jul;33(7):1332-9.
Title: Meat-related mutagen exposure, xenobiotic metabolizing gene polymorphisms and the risk of advanced colorectal adenoma and cancer.
Author: Gilsing, Anne M J|Berndt, Sonja I|Ruder, Elizabeth H|Graubard, Barry I|Ferrucci, Leah M|Burdett, Laura|Weissfeld, Joel L|Cross, Amanda J|Sinha, Rashmi
PMID: 22552404
Journal: Genet Mol Res. 2012 Sep 3;11(3):3138-45.
Title: CYP2E1 RsaI and 96-bp insertion genetic polymorphisms associated with risk for colorectal cancer.
Author: Silva, T D|Felipe, A V|Pimenta, C A M|Barao, K|Forones, N M
PMID: 23007992
Journal: Tumour Biol. 2013 Aug;34(4):2389-95.
Title: Associations of CYP2E1 rs2031920 and rs3813867 polymorphisms with colorectal cancer risk: a systemic review and meta-analysis.
Author: Peng, Hui|Xie, Shang-Kui|Huang, Mei-Jin|Ren, Dong-Lin
PMID: 23595220
Journal: Zhonghua Liu Xing Bing Xue Za Zhi. 2013 Oct;34(10):1013-7.
Title: [Role of alcohol-metabolizing enzymes gene polymorphisms and environmental exposure on colorectal cancer: a case-only study].
Author: Zhao, Hao|Li, Ting-ting|Yin, Jie-yun|Qin, Qin|Shi, Yun|Tian, Li-hong|Nie, Shao-fa|Wang, Xin|Liu, Li
PMID: 24377999
Journal: Asian Pac J Cancer Prev. 2013;14(6):3761-8.
Title: Cytochrome P450 1A1, 2E1 and GSTM1 gene polymorphisms and susceptibility to colorectal cancer in the Saudi population.
Author: Saeed, Hesham Mahmoud|Alanazi, Mohammad Saud|Nounou, Howaida Attia|Salaby, Manal Ali|Semlali, Abdelhabib|Azzam, Nahla|Aljebreen, Abdeulrahan|Alharby, Othman|Parine, Narasimha Reddy|Shaik, Jilani|Arafaha, Maha
PMID: 23886179
Journal: Tumour Biol. 2013 Aug;34(4):2225-31.
Title: CYP2E1 T7632A and 9-bp insertion polymorphisms and colorectal cancer risk: a meta-analysis based on 4,592 cases and 5,918 controls.
Author: Qian, Jun|Song, Zhangfa|Lv, Yinxiang|Huang, Xuefeng
PMID: 23636797
Journal: Epigenetics. 2013 Feb;8(2):157-63.
Title: Human metastable epiallele candidates link to common disorders.
Author: Harris, R Alan|Nagy-Szakal, Dorottya|Kellermayer, Richard
PMID: 23321599
Journal: BMJ Open. 2014 Jan 6;4(1):e004109.
Title: RsaI but not DraI polymorphism in CYP2E1 gene increases the risk of gastrointestinal cancer in Malaysians: a case-control study.
Author: Chong, Eric Tzyy Jiann|Lee, Chong Cin|Chua, Kek Heng|Chuah, Jitt Aun|Lee, Ping-Chin
PMID: 24394801
Journal: Cell Physiol Biochem. 2014;33(5):1400-10.
Title: Short-term effects of oral administration of Pistacia lentiscus oil on tissue-specific toxicity and drug metabolizing enzymes in mice.
Author: Attoub, Samir|Karam, Sherif M|Nemmar, Abderrahim|Arafat, Kholoud|John, Annie|Al-Dhaheri, Wafa|Al Sultan, Mahmood Ahmed|Raza, Haider
PMID: 24853661
Journal: Br J Cancer. 2014 Dec 9;111(12):2287-96.
Title: Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3.
Author: Patel, S A A|Bhambra, U|Charalambous, M P|David, R M|Edwards, R J|Lightfoot, T|Boobis, A R|Gooderham, N J
PMID: 25333344
Journal: Adv Pharmacol. 2015;74:85-111.
Title: Polymorphic Variants of Cytochrome P450: Relevance to Cancer and Other Diseases.
Author: Daly, Ann K
PMID: 26233904
Journal: Genet Mol Res. 2015 Dec 22;14(4):17856-63.
Title: A case-control study of CYP2E1 (PstI) and CYP1A1 (MspI) polymorphisms in colorectal cancer.
Author: Proenca, M A|Fernandes, G M M|Russo, A|Lelis, R B|Netinho, J G|Cunrath, G S|Silva, A E|Goloni-Bertollo, E M|Pavarino, E C
PMID: 26782431
Journal: Alcohol Clin Exp Res. 2016 Oct;40(10):2094-2101.
Title: Possible Mechanisms of Ethanol-Mediated Colorectal Carcinogenesis: The Role of Cytochrome P4502E1, Etheno-DNA Adducts, and the Anti-Apoptotic Protein Mcl-1.
Author: Koehler, Bruno Christian|Arslic-Schmitt, Tatjana|Peccerella, Theresa|Scherr, Anna-Lena|Schulze-Bergkamen, Henning|Bruckner, Thomas|Gdynia, Georg|Jager, Dirk|Mueller, Sebastian|Bartsch, Helmut|Seitz, Helmut K
PMID: 27581253
Journal: World J Gastroenterol. 2016 Dec 7;22(45):9974-9983.
Title: CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms.
Author: Fernandes, Glaucia Maria M|Russo, Anelise|Proenca, Marcela Alcantara|Gazola, Nathalia Fernanda|Rodrigues, Gabriela Helena|Biselli-Chicote, Patricia Matos|Silva, Ana Elizabete|Netinho, Joao Gomes|Pavarino, Erika Cristina|Goloni-Bertollo, Eny Maria
PMID: 28018104
Journal: J Pathol. 2017 Apr;241(5):649-660.
Title: Effects of long-term ethanol consumption and Aldh1b1 depletion on intestinal tumourigenesis in mice.
Author: Muller, Mike F|Zhou, Ying|Adams, David J|Arends, Mark J
PMID: 28026023
Journal: Int J Mol Sci. 2017 May 24;18(6). pii: ijms18061116.
Title: Molecular Basis of Alcohol-Related Gastric and Colon Cancer.
Author: Na, Hye-Kyung|Lee, Ja Young
PMID: 28538665
Journal: World J Gastroenterol. 2017 Dec 28;23(48):8533-8543.
Title: Analysis of 12 variants in the development of gastric and colorectal cancers.
Author: Cavalcante, Giovanna C|Amador, Marcos At|Ribeiro Dos Santos, Andre M|Carvalho, Darlen C|Andrade, Roberta B|Pereira, Esdras Eb|Fernandes, Marianne R|Costa, Danielle F|Santos, Ney Pc|Assumpcao, Paulo P|Ribeiro Dos Santos, Andrea|Santos, Sidney
PMID: 29358861
Journal: Biotech Histochem. 2018 Aug 9:1-9.
Title: Expression of CYP and GST in human normal and colon tumor tissues.
Author: Bulus, H|Oguztuzun, S|Guler Simsek, G|Kilic, M|Ada, A Oguz|Gol, S|Kocdogan, A Kaya|Kaygin, P|Bozer, B|Iscan, M
PMID: 30092668