Primary Site >> Colorectal Cancer
Gene >> CYP2E1
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Ref: Induction of cyp2e-1 protein in mouse colon. PMID: 8293551 |
Ref: Effects of diet and ethanol on the expression and localization of cytochromes P450 2E1 and P450 2C7 in the colon of male rats. PMID: 8534269 Ref: A comparative study of hepatic and colonic metabolic enzymes in inbred mouse lines before and after treatment with the colon carcinogen, 1,2-dimethylhydrazine. PMID: 8801055 Ref: Effect of cytochrome P450 inducers on expression of oncogenes and a tumor suppressor gene in human colon cancer cells. PMID: 21541530 |
Ref: Effect of tea extracts, polyphenols, and epigallocatechin gallate on azoxymethane-induced colon cancer. PMID: 9421213 |
Ref: Decrease in hepatic cytochrome P450 after interleukin-2 immunotherapy. PMID: 10086330 Ref: Meat, metabolic genotypes and risk for colorectal cancer. PMID: 10443949 |
Ref: Colorectal cancer risk in relation to genetic polymorphism of cytochrome P450 1A1, 2E1, and glutathione-S-transferase M1 enzymes. PMID: 10769717 |
Ref: Metabolic genotypes and risk for colorectal cancer. PMID: 11422615 Ref: Host determinants of DNA alkylation and DNA repair activity in human colorectal tissue: O(6)-methylguanine levels are associated with GSTT1 genotype and O(6)-alkylguanine-DNA alkyltransferase activity with CYP2D6 genotype. PMID: 11448648 Ref: Effect of grape seed proanthocyanidins on colon aberrant crypts and breast tumors in a rat dual-organ tumor model. PMID: 11759289 |
Ref: Hemizygous mice for the angiotensin II type 2 receptor gene have attenuated susceptibility to azoxymethane-induced colon tumorigenesis. PMID: 12117783 Ref: Red meat intake, CYP2E1 genetic polymorphisms, and colorectal cancer risk. PMID: 12376502 |
Ref: [Genetic polymorphism in cytochrome P450 2E1, salted food and colorectal cancer susceptibility: a case-control study]. PMID: 15182482 |
Ref: Modulation of cytochrome P450 enzymes by organosulfur compounds from garlic. PMID: 16000231 Ref: A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer. PMID: 16006997 Ref: [A case-control study on the association between genetic polymorphisms of metabolic enzymes and the risk of colorectal cancer]. PMID: 16471212 Ref: Alcohol consumption and cancer of the gastrointestinal tract. PMID: 16508294 |
Ref: Role of epoxide hydrolase, NAD(P)H:quinone oxidoreductase, cytochrome P450 2E1 or alcohol dehydrogenase genotypes in susceptibility to colorectal cancer. PMID: 16039674 Ref: Effects of indole-3-carbinol and phenethyl isothiocyanate on colon carcinogenesis induced by azoxymethane in rats. PMID: 16113056 Ref: Diallylsulfide and allylmethylsulfide are uniquely effective among organosulfur compounds in inhibiting CYP2E1 protein in animal models. PMID: 16484575 Ref: Genetic polymorphism of xenobiotic metabolising enzymes, diet and cancer susceptibility. PMID: 17010218 |
Ref: Effect of chronic dietary ethanol consumption on colonic cancer in rats induced by 1,1-dimethylhydrazine. PMID: 17331170 Ref: Case-only study of interactions between metabolic enzymes and smoking in colorectal cancer. PMID: 17603900 Ref: Combinations of cytochrome P450 gene polymorphisms enhancing the risk for sporadic colorectal cancer related to red meat consumption. PMID: 17627011 Ref: Association between allelic polymorphisms of metabolizing enzymes (CYP 1A1, CYP 1A2, CYP 2E1, mEH) and occurrence of colorectal cancer in Hungary. PMID: 17695473 Ref: CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking. PMID: 17963298 |
Ref: Development of aberrant crypt foci in the colons of ob/ob and db/db mice: evidence that leptin is not a promoter. PMID: 18240295 Ref: Cruciferous vegetables reduce morphological markers of colon cancer risk in dimethylhydrazine-treated rats. PMID: 18287361 Ref: Genetic polymorphisms of CYP2E1 and risk of colorectal adenomas in the Self Defense Forces Health Study. PMID: 18628434 |
Ref: Genetic polymorphisms of CYP2E1 and risk of colorectal cancer: the Fukuoka Colorectal Cancer Study. PMID: 19124503 Ref: The signal pathways in azoxymethane-induced colon cancer and preventive implications. PMID: 19502780 Ref: A novel polymorphism rs1329149 of CYP2E1 and a known polymorphism rs671 of ALDH2 of alcohol metabolizing enzymes are associated with colorectal cancer in a southwestern Chinese population. PMID: 19706845 |
Ref: CYP2E1 PstI/RsaI polymorphism and colorectal cancer risk: a meta-analysis. PMID: 20556843 |
Ref: CYP1A1, CYP2E1, and GSTM1 gene polymorphisms and susceptibility to colorectal and gastric cancer among Lebanese. PMID: 21385088 Ref: Role of CYP2E1 genotypes in susceptibility to colorectal cancer in the Kashmiri population. PMID: 22155602 Ref: Effects of Lactobacillus casei on the expression and the activity of cytochromes P450 and on the CYP mRNA level in the intestine and the liver of male rats. PMID: 22167211 |
Ref: Carcinogen metabolism genes, red meat and poultry intake, and colorectal cancer risk. PMID: 21618522 Ref: Association of GSTM1, GSTT1, GSTP1 and CYP2E1 single nucleotide polymorphisms with colorectal cancer in Iran. PMID: 22228187 Ref: High-fat diet alters gene expression in the liver and colon: links to increased development of aberrant crypt foci. PMID: 22373862 Ref: Meat-related mutagen exposure, xenobiotic metabolizing gene polymorphisms and the risk of advanced colorectal adenoma and cancer. PMID: 22552404 Ref: CYP2E1 RsaI and 96-bp insertion genetic polymorphisms associated with risk for colorectal cancer. PMID: 23007992 |
Ref: Human metastable epiallele candidates link to common disorders. PMID: 23321599 Ref: Associations of CYP2E1 rs2031920 and rs3813867 polymorphisms with colorectal cancer risk: a systemic review and meta-analysis. PMID: 23595220 Ref: CYP2E1 T7632A and 9-bp insertion polymorphisms and colorectal cancer risk: a meta-analysis based on 4,592 cases and 5,918 controls. PMID: 23636797 Ref: Cytochrome P450 1A1, 2E1 and GSTM1 gene polymorphisms and susceptibility to colorectal cancer in the Saudi population. PMID: 23886179 Ref: [Role of alcohol-metabolizing enzymes gene polymorphisms and environmental exposure on colorectal cancer: a case-only study]. PMID: 24377999 |
Ref: RsaI but not DraI polymorphism in CYP2E1 gene increases the risk of gastrointestinal cancer in Malaysians: a case-control study. PMID: 24394801 Ref: Short-term effects of oral administration of Pistacia lentiscus oil on tissue-specific toxicity and drug metabolizing enzymes in mice. PMID: 24853661 Ref: Interleukin-6 mediated upregulation of CYP1B1 and CYP2E1 in colorectal cancer involves DNA methylation, miR27b and STAT3. PMID: 25333344 |
Ref: Polymorphic Variants of Cytochrome P450: Relevance to Cancer and Other Diseases. PMID: 26233904 Ref: A case-control study of CYP2E1 (PstI) and CYP1A1 (MspI) polymorphisms in colorectal cancer. PMID: 26782431 |
Ref: Possible Mechanisms of Ethanol-Mediated Colorectal Carcinogenesis: The Role of Cytochrome P4502E1, Etheno-DNA Adducts, and the Anti-Apoptotic Protein Mcl-1. PMID: 27581253 Ref: CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms. PMID: 28018104 |
Ref: Effects of long-term ethanol consumption and Aldh1b1 depletion on intestinal tumourigenesis in mice. PMID: 28026023 Ref: Molecular Basis of Alcohol-Related Gastric and Colon Cancer. PMID: 28538665 Ref: Analysis of 12 variants in the development of gastric and colorectal cancers. PMID: 29358861 |
Ref: Expression of CYP and GST in human normal and colon tumor tissues. PMID: 30092668 |