Primary Site >> Colorectal Cancer

Gene >> CYP2D6

Journal: Acta Neuropathol. 1994;88(5):472-4.
Title: Debrisoquine hydroxylase gene polymorphism in meningioma.
Author: Wundrack, I|Meese, E|Mullenbach, R|Blin, N
PMID: 7847077
Journal: Clin Chem. 1995 Dec;41(12 Pt 2):1864-9.
Title: Polymorphisms in drug-metabolizing enzymes as modifiers of cancer risk.
Author: Spurr, N K|Gough, A C|Chinegwundoh, F I|Smith, C A
PMID: 7497646
Journal: Mol Pharmacol. 1997 May;51(5):741-54.
Title: Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3.
Author: Schmiedlin-Ren, P|Thummel, K E|Fisher, J M|Paine, M F|Lown, K S|Watkins, P B
PMID: 9145912
Journal: Anticancer Res. 1997 Nov-Dec;17(6D):4515-7.
Title: Debrisoquine hydroxylase gene polymorphism in neurofibromatosis type 1.
Author: Wundrack, I|Sasiadek, M|Blin, N
PMID: 9494560
Journal: Cancer Chemother Pharmacol. 2000;45(4):298-304.
Title: N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine (DPPE) a chemopotentiating and cytoprotective agent in clinical trials: interaction with histamine at cytochrome P450 3A4 and other isozymes that metabolize antineoplastic drugs.
Author: Brandes, L J|Queen, G M|LaBella, F S
PMID: 10755318
Journal: J Gastroenterol Hepatol. 2001 Jun;16(6):631-5.
Title: Metabolic genotypes and risk for colorectal cancer.
Author: Butler, W J|Ryan, P|Roberts-Thomson, I C
PMID: 11422615
Journal: Mutat Res. 2001 Aug 22;495(1-2):103-15.
Title: Host determinants of DNA alkylation and DNA repair activity in human colorectal tissue: O(6)-methylguanine levels are associated with GSTT1 genotype and O(6)-alkylguanine-DNA alkyltransferase activity with CYP2D6 genotype.
Author: Povey, A C|Hall, C N|Badawi, A F|Cooper, D P|Guppy, M J|Jackson, P E|O'Connor, P J|Margison, G P
PMID: 11448648
Journal: Carcinogenesis. 2002 Nov;23(11):1839-49.
Title: A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer.
Author: Sachse, Christoph|Smith, Gillian|Wilkie, Murray J V|Barrett, Jennifer H|Waxman, Robin|Sullivan, Frank|Forman, David|Bishop, D Timothy|Wolf, C Roland
PMID: 12419832
Journal: Pharmacogenet Genomics. 2005 Aug;15(8):535-46.
Title: A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer.
Author: Landi, Stefano|Gemignani, Federica|Moreno, Victor|Gioia-Patricola, Lydie|Chabrier, Amelie|Guino, Elisabeth|Navarro, Matilde|de Oca, Javier|Capella, Gabriel|Canzian, Federico
PMID: 16006997
Journal: Invest New Drugs. 2008 Feb;26(1):25-34.
Title: Pharmacological evaluation of C-3 modified Betulinic acid derivatives with potent anticancer activity.
Author: Rajendran, Praveen|Jaggi, Manu|Singh, Manoj K|Mukherjee, Rama|Burman, Anand C
PMID: 17851638
Journal: BMC Med Genomics. 2008 Jun 11;1:24.
Title: Genotyping panel for assessing response to cancer chemotherapy.
Author: Dai, Zunyan|Papp, Audrey C|Wang, Danxin|Hampel, Heather|Sadee, Wolfgang
PMID: 18547414
Journal: Clin Lab Med. 2008 Dec;28(4):553-67.
Title: Pharmacogenomics of tamoxifen and irinotecan therapies.
Author: Algeciras-Schimnich, Alicia|O'Kane, Dennis J|Snozek, Christine L H
PMID: 19059062
Journal: J Mol Diagn. 2009 Sep;11(5):381-9.
Title: Pharmacogenetics of solid tumors: directed therapy in breast, lung, and colorectal cancer: a paper from the 2008 william beaumont hospital symposium on molecular pathology.
Author: Snozek, Christine L H|O'Kane, Dennis J|Algeciras-Schimnich, Alicia
PMID: 19644023
Journal: Pharmacogenet Genomics. 2010 May;20(5):315-26.
Title: Polymorphisms in xenobiotic metabolizing enzymes and diet influence colorectal adenoma risk.
Author: Northwood, Emma L|Elliott, Faye|Forman, David|Barrett, Jennifer H|Wilkie, Murray J V|Carey, Francis A|Steele, Robert J C|Wolf, Roland|Bishop, Timothy|Smith, Gillian
PMID: 20375710
Journal: Wien Med Wochenschr. 2010 Apr;160(7-8):167-73.
Title: Adjuvant endocrine therapy of premenopausal women with early breast cancer: an overview.
Author: Hubalek, Michael|Brantner, Christine|Marth, Christian
PMID: 20473727
Journal:
Title:
Author: Terasawa, Teruhiko|Dahabreh, Issa|Castaldi, Peter J|Trikalinos, Thomas A
PMID: 26065050
Journal: Org Med Chem Lett. 2012 Jun 11;2(1):21.
Title: Cytotoxic and potent CYP1 inhibitors from the marine algae Cymopolia barbata.
Author: Badal, Simone|Gallimore, Winklet|Huang, George|Tzeng, Tzuen-Rong Jeremy|Delgoda, Rupika
PMID: 22686946
Journal: J Cancer Epidemiol. 2012;2012:294730.
Title: Patterns of cancer genetic testing: a randomized survey of Oregon clinicians.
Author: Cox, Summer L|Zlot, Amy I|Silvey, Kerry|Elliott, Debi|Horn, Tara|Johnson, Amber|Leman, Richard F
PMID: 23150730
Journal: Clin Cancer Res. 2013 Jan 15;19(2):500-7.
Title: CYP2D6 metabolism and patient outcome in the Austrian Breast and Colorectal Cancer Study Group trial (ABCSG) 8.
Author: Goetz, Matthew P|Suman, Vera J|Hoskin, Tanya L|Gnant, Michael|Filipits, Martin|Safgren, Stephanie L|Kuffel, Mary|Jakesz, Raimund|Rudas, Margaretha|Greil, Richard|Dietze, Otto|Lang, Alois|Offner, Felix|Reynolds, Carol A|Weinshilboum, Richard M|Ames, Matthe
PMID: 23213055
Journal: Clin Pharmacokinet. 2013 Nov;52(11):919-26.
Title: Breath tests to phenotype drug disposition in oncology.
Author: Opdam, Frans L|Modak, Anil S|Gelderblom, Hans|Guchelaar, Henk-Jan
PMID: 23868281
Journal: Adv Pharmacol. 2015;74:85-111.
Title: Polymorphic Variants of Cytochrome P450: Relevance to Cancer and Other Diseases.
Author: Daly, Ann K
PMID: 26233904
Journal: J BUON. 2016 Sept-Oct;21(5):1287-1295.
Title: Pharmacogenetics in cancer therapy - 8 years of experience at the Institute for Oncology and Radiology of Serbia.
Author: Cavic, Milena|Krivokuca, Ana|Boljevic, Ivana|Brotto, Ksenija|Jovanovic, Katarina|Tanic, Miljana|Filipovic, Lana|Zec, Manja|Malisic, Emina|Jankovic, Radmila|Radulovic, Sinisa
PMID: 27837635
Journal: Res Pharm Sci. 2016 Oct;11(5):355-365.
Title: Pharmacological characterization of liquiritigenin, a chiral flavonoid in licorice.
Author: Alrushaid, Samaa|Davies, Neal M|Martinez, Stephanie E|Sayre, Casey L
PMID: 27920817
Journal: Drug Des Devel Ther. 2017 Sep 5;11:2621-2629.
Title: Recent developments in the clinical pharmacology of rolapitant: subanalyses in specific populations.
Author: Rapoport, Bernardo Leon|Aapro, Matti|Chasen, Martin R|Jordan, Karin|Navari, Rudolph M|Schnadig, Ian|Schwartzberg, Lee
PMID: 28919712