Primary Site >> Colorectal Cancer
Gene >> CYP2D6
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Ref: Debrisoquine hydroxylase gene polymorphism in meningioma. PMID: 7847077 |
Ref: Polymorphisms in drug-metabolizing enzymes as modifiers of cancer risk. PMID: 7497646 |
Ref: Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3. PMID: 9145912 Ref: Debrisoquine hydroxylase gene polymorphism in neurofibromatosis type 1. PMID: 9494560 |
Ref: N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine (DPPE) a chemopotentiating and cytoprotective agent in clinical trials: interaction with histamine at cytochrome P450 3A4 and other isozymes that metabolize antineoplastic drugs. PMID: 10755318 |
Ref: Metabolic genotypes and risk for colorectal cancer. PMID: 11422615 Ref: Host determinants of DNA alkylation and DNA repair activity in human colorectal tissue: O(6)-methylguanine levels are associated with GSTT1 genotype and O(6)-alkylguanine-DNA alkyltransferase activity with CYP2D6 genotype. PMID: 11448648 |
Ref: A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer. PMID: 12419832 |
Ref: A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer. PMID: 16006997 |
Ref: Pharmacological evaluation of C-3 modified Betulinic acid derivatives with potent anticancer activity. PMID: 17851638 Ref: Genotyping panel for assessing response to cancer chemotherapy. PMID: 18547414 Ref: Pharmacogenomics of tamoxifen and irinotecan therapies. PMID: 19059062 |
Ref: Pharmacogenetics of solid tumors: directed therapy in breast, lung, and colorectal cancer: a paper from the 2008 william beaumont hospital symposium on molecular pathology. PMID: 19644023 |
Ref: Polymorphisms in xenobiotic metabolizing enzymes and diet influence colorectal adenoma risk. PMID: 20375710 Ref: Adjuvant endocrine therapy of premenopausal women with early breast cancer: an overview. PMID: 20473727 Ref: PMID: 26065050 |
Ref: Cytotoxic and potent CYP1 inhibitors from the marine algae Cymopolia barbata. PMID: 22686946 Ref: Patterns of cancer genetic testing: a randomized survey of Oregon clinicians. PMID: 23150730 |
Ref: CYP2D6 metabolism and patient outcome in the Austrian Breast and Colorectal Cancer Study Group trial (ABCSG) 8. PMID: 23213055 Ref: Breath tests to phenotype drug disposition in oncology. PMID: 23868281 |
Ref: Polymorphic Variants of Cytochrome P450: Relevance to Cancer and Other Diseases. PMID: 26233904 |
Ref: Pharmacogenetics in cancer therapy - 8 years of experience at the Institute for Oncology and Radiology of Serbia. PMID: 27837635 Ref: Pharmacological characterization of liquiritigenin, a chiral flavonoid in licorice. PMID: 27920817 |
Ref: Recent developments in the clinical pharmacology of rolapitant: subanalyses in specific populations. PMID: 28919712 |