Primary Site >> Liver Cancer
Gene >> CYP2C19
| 1. | |||||||||||
| Journal: | Life Sci. 1996;59(20):1711-5. | ||||||||||
| Title: | Genotype analysis of the CYP2C19 gene in the Japanese population. | ||||||||||
| Author: | Tsuneoka, Y|Fukushima, K|Matsuo, Y|Ichikawa, Y|Watanabe, Y | ||||||||||
| PMID: | 8890945 | ||||||||||
| 2. | |||||||||||
| Journal: | Life Sci. 2000 Aug 25;67(14):1719-24. | ||||||||||
| Title: | Genotype analysis of the CYP2C19 gene in HCV-seropositive patients with cirrhosis and hepatocellular carcinoma. | ||||||||||
| Author: | Chau, T K|Marakami, S|Kawai, B|Nasu, K|Kubota, T|Ohnishi, A | ||||||||||
| PMID: | 11021356 | ||||||||||
| 3. | |||||||||||
| Journal: | Curr Drug Metab. 2003 Jun;4(3):223-39. | ||||||||||
| Title: | Tamoxifen: is it safe? Comparison of activation and detoxication mechanisms in rodents and in humans. | ||||||||||
| Author: | White, I N H | ||||||||||
| PMID: | 12769667 | ||||||||||
| 4. | |||||||||||
| Journal: | Curr Drug Metab. 2004 Jun;5(3):211-24. | ||||||||||
| Title: | Cytochrome P450 gene polymorphism and cancer. | ||||||||||
| Author: | Agundez, Jose A G | ||||||||||
| PMID: | 15180491 | ||||||||||
| 5. | |||||||||||
| Journal: | J Gastroenterol Hepatol. 2005 Aug;20(8):1191-7. | ||||||||||
| Title: | Genetic polymorphisms of cytochrome P450 in patients with hepatitis C virus-associated hepatocellular carcinoma. | ||||||||||
| Author: | Mochizuki, Junko|Murakami, Shigeto|Sanjo, Akira|Takagi, Ichiro|Akizuki, Setsuko|Ohnishi, Akihiro | ||||||||||
| PMID: | 16048566 | ||||||||||
| 6. | |||||||||||
| Journal: | Int J Oncol. 2005 Sep;27(3):661-7. | ||||||||||
| Title: | Patterns of expression of cytochrome P450 genes in progression of hepatitis C virus-associated hepatocellular carcinoma. | ||||||||||
| Author: | Tsunedomi, Ryouichi|Iizuka, Norio|Hamamoto, Yoshihiko|Uchimura, Shunji|Miyamoto, Takanobu|Tamesa, Takao|Okada, Toshimasa|Takemoto, Norikazu|Takashima, Motonari|Sakamoto, Kazuhiko|Hamada, Kenji|Yamada-Okabe, Hisafumi|Oka, Masaaki | ||||||||||
| PMID: | 16077914 | ||||||||||
| 7. | |||||||||||
| Journal: | Med Sci Monit. 2006 May;12(5):BR174-8. | ||||||||||
| Title: | Differences in cytochrome P450 2C19 (CYP2C19) expression in adjacent normal and tumor tissues in Chinese cancer patients. | ||||||||||
| Author: | Wu, Minliang|Chen, Shuqing|Wu, Xiaohong | ||||||||||
| PMID: | 16641871 | ||||||||||
| 8. | |||||||||||
| Journal: | Acta Pharmacol Sin. 2013 Sep;34(9):1237-42. | ||||||||||
| Title: | Pungent ginger components modulates human cytochrome P450 enzymes in vitro. | ||||||||||
| Author: | Li, Mian|Chen, Pei-zhan|Yue, Qing-xi|Li, Jing-quan|Chu, Rui-ai|Zhang, Wei|Wang, Hui | ||||||||||
| PMID: | 23770984 | ||||||||||
| 9. | |||||||||||
| Journal: | PLoS One. 2013 Aug 27;8(8):e73126. | ||||||||||
| Title: | Poor metabolizers at the cytochrome P450 2C19 loci is at increased risk of developing cancer in Asian populations. | ||||||||||
| Author: | Wang, Hong|Song, Kang|Chen, Zenggan|Yu, Yanmin | ||||||||||
| PMID: | 24015291 | ||||||||||
| 10. | |||||||||||
| Journal: | World J Gastroenterol. 2014 Jul 14;20(26):8681-90. | ||||||||||
| Title: | Expression of P450 and nuclear receptors in normal and end-stage Chinese livers. | ||||||||||
| Author: | Chen, Hong|Shen, Zhong-Yang|Xu, Wang|Fan, Tie-Yan|Li, Jun|Lu, Yuan-Fu|Cheng, Ming-Liang|Liu, Jie | ||||||||||
| PMID: | 25024626 | ||||||||||
| 11. | |||||||||||
| Journal: | Tumour Biol. 2014 Sep;35(9):9023-6. | ||||||||||
| Title: | Individuals having variant genotypes of cytochrome P450 2C19 are at increased risk of developing primary liver cancer in Han populations, without infection with the hepatitis virus. | ||||||||||
| Author: | Li, Qiao-Yan|Zhao, Ning-Min|Wang, Lian-Cai|Duan, Hong-Fei|Ma, Yong-Cheng|Zhang, Wei|Zhao, Hong-Wei|Qin, Yu-Hua | ||||||||||
| PMID: | 24906606 | ||||||||||
| 12. | |||||||||||
| Journal: | J Ethnopharmacol. 2014;151(1):210-7. | ||||||||||
| Title: | Marsdenia tenacissima extract inhibits gefitinib metabolism in vitro by interfering with human hepatic CYP3A4 and CYP2D6 enzymes. | ||||||||||
| Author: | Han, Shu-Yan|Zhao, Hai-Yu|Zhou, Ning|Zhou, Fei|Li, Ping-Ping | ||||||||||
| PMID: | 24157377 | ||||||||||
| 13. | |||||||||||
| Journal: | Pharm Res. 2015 Mar;32(3):1141-57. | ||||||||||
| Title: | Significantly decreased and more variable expression of major CYPs and UGTs in liver microsomes prepared from HBV-positive human hepatocellular carcinoma and matched pericarcinomatous tissues determined using an isotope label-free UPLC-MS/MS method. | ||||||||||
| Author: | Yan, Tongmeng|Gao, Song|Peng, Xiaojuan|Shi, Jian|Xie, Cong|Li, Qiang|Lu, Linlin|Wang, Ying|Zhou, Fuyuan|Liu, Zhongqiu|Hu, Ming | ||||||||||
| PMID: | 25288013 | ||||||||||
| 14. | |||||||||||
| Journal: | Cancer Sci. 2015 May;106(5):611-7. | ||||||||||
| Title: | Phase I study of tivantinib in Japanese patients with advanced hepatocellular carcinoma: Distinctive pharmacokinetic profiles from other solid tumors. | ||||||||||
| Author: | Okusaka, Takuji|Aramaki, Takeshi|Inaba, Yoshitaka|Nakamura, Shinichiro|Morimoto, Manabu|Moriguchi, Michihisa|Sato, Takashi|Ikawa, Yuta|Ikeda, Masafumi|Furuse, Junji | ||||||||||
| PMID: | 25711511 | ||||||||||
| 15. | |||||||||||
| Journal: | Asian Pac J Cancer Prev. 2015;16(8):3253-6. | ||||||||||
| Title: | CYP2C19 Genotype Could be a Predictive Factor for Aggressive Manifestations of Hepatocellular Carcinoma Related with Chronic Hepatitis B Infection in Thailand. | ||||||||||
| Author: | Nun-Anan, Pongjarat|Chonprasertsuk, Soonthorn|Siramolpiwat, Sith|Tangaroonsanti, Anupong|Bhanthumkomol, Patommatat|Pornthisarn, Bubpha|Vilaichone, Ratha-Korn | ||||||||||
| PMID: | 25921128 | ||||||||||
| 16. | |||||||||||
| Journal: | Adv Pharmacol. 2015;74:85-111. | ||||||||||
| Title: | Polymorphic Variants of Cytochrome P450: Relevance to Cancer and Other Diseases. | ||||||||||
| Author: | Daly, Ann K | ||||||||||
| PMID: | 26233904 | ||||||||||
| 17. | |||||||||||
| Journal: | Oncotarget. 2016 Aug 2;7(31):50612-50623. | ||||||||||
| Title: | Significant change of cytochrome P450s activities in patients with hepatocellular carcinoma. | ||||||||||
| Author: | Zhou, Jun|Wen, Qiang|Li, Sai-Fei|Zhang, Yun-Fei|Gao, Na|Tian, Xin|Fang, Yan|Gao, Jie|Cui, Ming-Zhu|He, Xiao-Pei|Jia, Lin-Jing|Jin, Han|Qiao, Hai-Ling | ||||||||||
| PMID: | 27203676 | ||||||||||
| 18. | |||||||||||
| Journal: | Drug Metab Dispos. 2016 Oct;44(10):1643-52. | ||||||||||
| Title: | Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus-Associated Hepatocellular Carcinoma. | ||||||||||
| Author: | Tang, Xiaojing|Ge, Lele|Chen, Zhongjian|Kong, Sisi|Liu, Wenhui|Xu, Yingchun|Zeng, Su|Chen, Shuqing | ||||||||||
| PMID: | 27440862 | ||||||||||
| 19. | |||||||||||
| Journal: | Basic Clin Pharmacol Toxicol. 2017 Oct;121(4):334-341. | ||||||||||
| Title: | Cis-Nerolidol Induces Endoplasmic Reticulum Stress and Cell Death in Human Hepatocellular Carcinoma Cells through Extensive CYP2C19 and CYP1A2 Oxidation. | ||||||||||
| Author: | Biazi, Bruna Isabela|Zanetti, Thalita Alves|Baranoski, Adrivanio|Corveloni, Amanda Cristina|Mantovani, Mario Sergio | ||||||||||
| PMID: | 28256105 | ||||||||||
| 20. | |||||||||||
| Journal: | Br J Cancer. 2017 Sep 26;117(7):965-973. | ||||||||||
| Title: | Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228). | ||||||||||
| Author: | Levi, Francis|Karaboue, Abdoulaye|Saffroy, Raphael|Desterke, Christophe|Boige, Valerie|Smith, Denis|Hebbar, Mohamed|Innominato, Pasquale|Taieb, Julien|Carvalho, Carlos|Guimbaud, Rosine|Focan, Christian|Bouchahda, Mohamed|Adam, Rene|Ducreux, Michel|Milano, | ||||||||||
| PMID: | 28817838 | ||||||||||
| 21. | |||||||||||
| Journal: | Cancer Med. 2018 Apr;7(4):966-980. | ||||||||||
| Title: | The prognostic value of CYP2C subfamily genes in hepatocellular carcinoma. | ||||||||||
| Author: | Wang, Xiangkun|Yu, Tingdong|Liao, Xiwen|Yang, Chengkun|Han, Chuangye|Zhu, Guangzhi|Huang, Ketuan|Yu, Long|Qin, Wei|Su, Hao|Liu, Xiaoguang|Peng, Tao | ||||||||||
| PMID: | 29479826 | ||||||||||
| 22. | |||||||||||
| Journal: | Oncotarget. 2018 Apr 24;9(31):22058-22068. | ||||||||||
| Title: | The down-regulation of the CYP2C19 gene is associated with aggressive tumor potential and the poorer recurrence-free survival of hepatocellular carcinoma. | ||||||||||
| Author: | Ashida, Ryo|Okamura, Yukiyasu|Ohshima, Keiichi|Kakuda, Yuko|Uesaka, Katsuhiko|Sugiura, Teiichi|Ito, Takaaki|Yamamoto, Yusuke|Sugino, Takashi|Urakami, Kenichi|Kusuhara, Masatoshi|Yamaguchi, Ken | ||||||||||
| PMID: | 29774122 | ||||||||||
| 23. | |||||||||||
| Journal: | Biomed Environ Sci. 2018 Aug;31(8):586-595. | ||||||||||
| Title: | Specific CYP450 Genotypes in the Chinese Population Affect Sorafenib Toxicity in HBV/HCV-associated Hepatocellular Carcinoma Patients. | ||||||||||
| Author: | Guo, Xing Gang|Wang, Zhi Heng|Dong, Wei|He, Xu Dong|Liu, Fu Chen|Liu, Hui | ||||||||||
| PMID: | 30231963 | ||||||||||