Primary Site >> Liver Cancer
Gene >> CYP2C19
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Genotype analysis of the CYP2C19 gene in the Japanese population. PMID: 8890945 |
Ref: Genotype analysis of the CYP2C19 gene in HCV-seropositive patients with cirrhosis and hepatocellular carcinoma. PMID: 11021356 |
Ref: Tamoxifen: is it safe? Comparison of activation and detoxication mechanisms in rodents and in humans. PMID: 12769667 |
Ref: Cytochrome P450 gene polymorphism and cancer. PMID: 15180491 |
Ref: Genetic polymorphisms of cytochrome P450 in patients with hepatitis C virus-associated hepatocellular carcinoma. PMID: 16048566 Ref: Patterns of expression of cytochrome P450 genes in progression of hepatitis C virus-associated hepatocellular carcinoma. PMID: 16077914 |
Ref: Differences in cytochrome P450 2C19 (CYP2C19) expression in adjacent normal and tumor tissues in Chinese cancer patients. PMID: 16641871 |
Ref: Pungent ginger components modulates human cytochrome P450 enzymes in vitro. PMID: 23770984 Ref: Poor metabolizers at the cytochrome P450 2C19 loci is at increased risk of developing cancer in Asian populations. PMID: 24015291 |
Ref: Marsdenia tenacissima extract inhibits gefitinib metabolism in vitro by interfering with human hepatic CYP3A4 and CYP2D6 enzymes. PMID: 24157377 Ref: Individuals having variant genotypes of cytochrome P450 2C19 are at increased risk of developing primary liver cancer in Han populations, without infection with the hepatitis virus. PMID: 24906606 Ref: Expression of P450 and nuclear receptors in normal and end-stage Chinese livers. PMID: 25024626 |
Ref: Significantly decreased and more variable expression of major CYPs and UGTs in liver microsomes prepared from HBV-positive human hepatocellular carcinoma and matched pericarcinomatous tissues determined using an isotope label-free UPLC-MS/MS method. PMID: 25288013 Ref: Phase I study of tivantinib in Japanese patients with advanced hepatocellular carcinoma: Distinctive pharmacokinetic profiles from other solid tumors. PMID: 25711511 Ref: CYP2C19 Genotype Could be a Predictive Factor for Aggressive Manifestations of Hepatocellular Carcinoma Related with Chronic Hepatitis B Infection in Thailand. PMID: 25921128 Ref: Polymorphic Variants of Cytochrome P450: Relevance to Cancer and Other Diseases. PMID: 26233904 |
Ref: Significant change of cytochrome P450s activities in patients with hepatocellular carcinoma. PMID: 27203676 Ref: Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus-Associated Hepatocellular Carcinoma. PMID: 27440862 |
Ref: Cis-Nerolidol Induces Endoplasmic Reticulum Stress and Cell Death in Human Hepatocellular Carcinoma Cells through Extensive CYP2C19 and CYP1A2 Oxidation. PMID: 28256105 Ref: Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228). PMID: 28817838 |
Ref: The prognostic value of CYP2C subfamily genes in hepatocellular carcinoma. PMID: 29479826 Ref: The down-regulation of the CYP2C19 gene is associated with aggressive tumor potential and the poorer recurrence-free survival of hepatocellular carcinoma. PMID: 29774122 Ref: Specific CYP450 Genotypes in the Chinese Population Affect Sorafenib Toxicity in HBV/HCV-associated Hepatocellular Carcinoma Patients. PMID: 30231963 |