Primary Site >> Stomach Cancer

Gene >> CYP2A6

Journal: Pharmacogenetics. 2002 Jun;12(4):299-306.
Title: A novel mutant allele of the CYP2A6 gene (CYP2A6*11 ) found in a cancer patient who showed poor metabolic phenotype towards tegafur.
Author: Daigo, Satoshi|Takahashi, Yoshiki|Fujieda, Masaki|Ariyoshi, Noritaka|Yamazaki, Hiroshi|Koizumi, Wasaburo|Tanabe, Satoshi|Saigenji, Katsunori|Nagayama, Sekio|Ikeda, Kazumasa|Nishioka, Yasuhiko|Kamataki, Tetsuya
PMID: 12042667
Journal: Int J Cancer. 2002 Aug 1;100(4):425-8.
Title: Effects of cytochrome P450 (CYP) 2A6 gene deletion and CYP2E1 genotypes on gastric adenocarcinoma.
Author: Tsukino, Hiromasa|Kuroda, Yoshiki|Qiu, Delai|Nakao, Hiroyuki|Imai, Hirohisa|Katoh, Takahiko
PMID: 12115524
Journal: J Clin Oncol. 2005 Oct 1;23(28):6957-65.
Title: Phase I pharmacokinetic study of S-1 plus cisplatin in patients with advanced gastric carcinoma.
Author: Ajani, Jaffer A|Faust, Josephine|Ikeda, Kazumasa|Yao, James C|Anbe, Hiroshi|Carr, Kelli L|Houghton, Michele|Urrea, Peter
PMID: 16145066
Journal: Gan To Kagaku Ryoho. 2006 Jun;33 Suppl 1:117-20.
Title: Rapid development of S-1 in the west for therapy of advanced gastric carcinoma.
Author: Ajani, Jaffer A
PMID: 16897985
Journal: Int J Clin Oncol. 2008 Jun;13(3):206-11.
Title: Challenges in predicting the clinical outcome in S-1-based chemotherapy for gastric cancer patients.
Author: Ichikawa, Wataru|Sasaki, Yasutsuna
PMID: 18553229
Journal: Int J Oncol. 2009 Mar;34(3):787-96.
Title: Copy number changes can be a predictor for hemoglobin reduction after S-1 monotherapy in gastric cancer.
Author: Jeung, Hei Cheul|Rha, Sun Young|Park, Chan Hee|Im, Chong-Kun|Shin, Sang Joon|Ahn, Joong Bae|Noh, Sung Hoon|Roh, Jae Kyung|Chung, Hyun Cheol
PMID: 19212683
Journal: Future Oncol. 2011 Jun;7(6):715-26.
Title: A comprehensive review of S-1 in the treatment of advanced gastric adenocarcinoma.
Author: Blum, Mariela|Suzuki, Akihiro|Ajani, Jaffer A
PMID: 21675835
Journal: Cancer Chemother Pharmacol. 2013 Nov;72(5):953-64.
Title: Phase I clinical and pharmacokinetic/pharmacogenetic study of a triplet regimen of S-1/irinotecan/oxaliplatin in patients with metastatic colorectal or gastric cancer.
Author: Park, Sook Ryun|Hong, Yong Sang|Lim, Hyeong-Seok|Seong, Moon-Woo|Kong, Sun-Young|Kim, Sun Young|Park, Young-Iee|Jung, Kyung Hae
PMID: 23982118
Journal: Mol Clin Oncol. 2014 Jan;2(1):93-98.
Title: Dose-finding study on adjuvant chemotherapy with S-1 plus oxaliplatin for gastric cancer.
Author: Yang, Lin|Yang, Yi|Qin, Qiong|Zhou, Aiping|Zhao, Jianjun|Wang, Jinwan|Shu, Chang|Yuan, Xinghua|Hu, Songnian
PMID: 24649314
Journal: PLoS One. 2015 Jul 16;10(7):e0131793.
Title: The Effect of 5-Aminolevulinic Acid on Cytochrome P450-Mediated Prodrug Activation.
Author: Miura, Mai|Ito, Kensuke|Hayashi, Maiko|Nakajima, Motowo|Tanaka, Tohru|Ogura, Shun-ichiro
PMID: 26181717
Journal: Gastric Cancer. 2016 Apr;19(2):586-96.
Title: A phase II study of perioperative S-1 combined with weekly docetaxel in patients with locally advanced gastric carcinoma: clinical outcomes and clinicopathological and pharmacogenetic predictors for survival.
Author: Kim, Young-Woo|Kim, Mi-Jung|Ryu, Keun Won|Lim, Hyeong-Seok|Lee, Jun Ho|Kong, Sun-Young|Lee, Jong Seok|Choi, Il Ju|Kim, Chan Gyoo|Lee, Jong Yeul|Cho, Soo-Jeong|Kook, Myeong-Cherl|Park, Young-Iee|Kim, Seok-Ki|Park, Sook Ryun
PMID: 25851942
Journal: Gastric Cancer. 2017 Jan;20(1):146-155.
Title: Associations between CYP2A6 polymorphisms and outcomes of adjuvant S-1 chemotherapy in patients with curatively resected gastric cancer.
Author: Jeong, Jae Ho|Park, Sook Ryun|Ahn, Yongchel|Ryu, Min-Hee|Ryoo, Baek-Yeol|Kong, Sun-Young|Yook, Jeong Hwan|Yoo, Moon-Won|Kim, Beom Su|Kim, Byung Sik|Kang, Yoon-Koo
PMID: 26715117
Journal: Cancer Chemother Pharmacol. 2017 Jan;79(1):69-79.
Title: Phase II trial of S-1 plus leucovorin in patients with advanced gastric cancer and clinical prediction by S-1 pharmacogenetic pathway.
Author: He, Ming-Ming|Zhang, Dong-Sheng|Wang, Feng|Wang, Zi-Xian|Yuan, Shu-Qiang|Wang, Zhi-Qiang|Luo, Hui-Yan|Ren, Chao|Qiu, Miao-Zhen|Jin, Ying|Wang, De-Shen|Chen, Dong-Liang|Zeng, Zhao-Lei|Li, Yu-Hong|He, Yang-Yang|Hao, Yuan-Tao|Guo, Pi|Wang, Feng-Hua|Zeng, Yi-
PMID: 27913881
Journal: Genomics Proteomics Bioinformatics. 2017 Aug;15(4):255-262.
Title: CYP2A6 Polymorphisms Associate with Outcomes of S-1 Plus Oxaliplatin Chemotherapy in Chinese Gastric Cancer Patients.
Author: Yang, Lin|Zou, Shanshan|Shu, Chang|Song, Yan|Sun, Yong-Kun|Zhang, Wen|Zhou, Aiping|Yuan, Xinghua|Yang, Yi|Hu, Songnian
PMID: 28811232
Journal: Zhonghua Yi Xue Za Zhi. 2018 Jun 26;98(24):1915-1918.
Title: [The influence of CYP2A6 polymorphism on adjuvant S-1 chemotherapy outcomes in patients with curatively resected gastric cancer].
Author: Hu, F K|Shen, J|Gao, S W
PMID: 29996281