Primary Site >> Stomach Cancer
Gene >> CYP2A6
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Ref: A novel mutant allele of the CYP2A6 gene (CYP2A6*11 ) found in a cancer patient who showed poor metabolic phenotype towards tegafur. PMID: 12042667 Ref: Effects of cytochrome P450 (CYP) 2A6 gene deletion and CYP2E1 genotypes on gastric adenocarcinoma. PMID: 12115524 |
Ref: Phase I pharmacokinetic study of S-1 plus cisplatin in patients with advanced gastric carcinoma. PMID: 16145066 |
Ref: Rapid development of S-1 in the west for therapy of advanced gastric carcinoma. PMID: 16897985 |
Ref: Challenges in predicting the clinical outcome in S-1-based chemotherapy for gastric cancer patients. PMID: 18553229 |
Ref: Copy number changes can be a predictor for hemoglobin reduction after S-1 monotherapy in gastric cancer. PMID: 19212683 |
Ref: A comprehensive review of S-1 in the treatment of advanced gastric adenocarcinoma. PMID: 21675835 |
Ref: Phase I clinical and pharmacokinetic/pharmacogenetic study of a triplet regimen of S-1/irinotecan/oxaliplatin in patients with metastatic colorectal or gastric cancer. PMID: 23982118 |
Ref: Dose-finding study on adjuvant chemotherapy with S-1 plus oxaliplatin for gastric cancer. PMID: 24649314 |
Ref: The Effect of 5-Aminolevulinic Acid on Cytochrome P450-Mediated Prodrug Activation. PMID: 26181717 |
Ref: A phase II study of perioperative S-1 combined with weekly docetaxel in patients with locally advanced gastric carcinoma: clinical outcomes and clinicopathological and pharmacogenetic predictors for survival. PMID: 25851942 |
Ref: Associations between CYP2A6 polymorphisms and outcomes of adjuvant S-1 chemotherapy in patients with curatively resected gastric cancer. PMID: 26715117 Ref: Phase II trial of S-1 plus leucovorin in patients with advanced gastric cancer and clinical prediction by S-1 pharmacogenetic pathway. PMID: 27913881 Ref: CYP2A6 Polymorphisms Associate with Outcomes of S-1 Plus Oxaliplatin Chemotherapy in Chinese Gastric Cancer Patients. PMID: 28811232 |
Ref: [The influence of CYP2A6 polymorphism on adjuvant S-1 chemotherapy outcomes in patients with curatively resected gastric cancer]. PMID: 29996281 |