Primary Site >> Colorectal Cancer

Gene >> CYP2A6

Journal: Jpn J Cancer Res. 2001 May;92(5):524-8.
Title: Expression of CYP2A6 in tumor cells augments cellular sensitivity to tegafur.
Author: Murayama, N|Sai, K|Nakajima, Y|Kaniwa, N|Ozawa, S|Ohno, Y|Sawada , J
PMID: 11376561
Journal: Cancer Epidemiol Biomarkers Prev. 2002 Apr;11(4):377-83.
Title: CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk.
Author: Nowell, Susan|Sweeney, Carol|Hammons, George|Kadlubar, Fred F|Lang, Nicholas P
PMID: 11927498
Journal: Mutat Res. 2002 Sep 30;506-507:175-85.
Title: Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to risk.
Author: Nowell, Susan|Coles, Brian|Sinha, Rashmi|MacLeod, Stewart|Luke Ratnasinghe, D|Stotts, Craig|Kadlubar, Fred F|Ambrosone, Christine B|Lang, Nicholas P
PMID: 12351157
Journal: Carcinogenesis. 2002 Nov;23(11):1839-49.
Title: A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer.
Author: Sachse, Christoph|Smith, Gillian|Wilkie, Murray J V|Barrett, Jennifer H|Waxman, Robin|Sullivan, Frank|Forman, David|Bishop, D Timothy|Wolf, C Roland
PMID: 12419832
Journal: Toxicology. 2002 Dec 27;181-182:83-7.
Title: Novel markers of susceptibility to carcinogens in diet: associations with colorectal cancer.
Author: Sweeney, Carol|Coles, Brian F|Nowell, Susan|Lang, Nicholas P|Kadlubar, Fred F
PMID: 12505289
Journal: Pharmacogenet Genomics. 2005 Aug;15(8):535-46.
Title: A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer.
Author: Landi, Stefano|Gemignani, Federica|Moreno, Victor|Gioia-Patricola, Lydie|Chabrier, Amelie|Guino, Elisabeth|Navarro, Matilde|de Oca, Javier|Capella, Gabriel|Canzian, Federico
PMID: 16006997
Journal: Cancer Sci. 2007 Oct;98(10):1582-5. Epub 2007 Aug 7.
Title: Overexpression of CYP2A6 in human colorectal tumors.
Author: Matsuda, Yoko|Saoo, Kousuke|Yamakawa, Keiko|Yokohira, Masanao|Suzuki, Satoshi|Kuno, Toshiya|Kamataki, Tetsuya|Imaida, Katsumi
PMID: 17683511
Journal: Ann Oncol. 2011 Feb;22(2):355-61.
Title: Associations of various gene polymorphisms with toxicity in colorectal cancer patients receiving oral uracil and tegafur plus leucovorin: a prospective study.
Author: Tsunoda, A|Nakao, K|Watanabe, M|Matsui, N|Ooyama, A|Kusano, M
PMID: 20647221
Journal: Farm Hosp. 2014 Jul 1;38(4):283-90.
Title: [Validation of genetic polymorphisms associated to the toxicity of chemotherapy in colorectal cancer patients].
Author: Cortejoso, L|Garcia, M I|Garcia-Alfonso, P|Gravalos, C|Robles, L|Gonzalez-Haba, E|Sanjurjo, M|Lopez-Fernandez, L A
PMID: 25137161
Journal: Interdiscip Sci. 2014 Nov 6.
Title: In-silico structural, virtual screening and docking studies of Human Cytochrome P450 2A7 protein.
Author: Lodhi, Sharad S|Farmer, Rohit|Jaiswal, Yogesh K|Wadhwa, Gulshan
PMID: 25519152
Journal: Interdiscip Sci. 2015 Jun;7(2):129-35.
Title: In Silico Structural, Virtual Screening and Docking Studies of Human Cytochrome P450 2A7 Protein.
Author: Lodhi, Sharad S|Farmer, Rohit|Jaiswal, Yogesh K|Wadhwa, Gulshan
PMID: 26239541
Journal: Radiat Oncol. 2017 Mar 27;12(1):62.
Title: A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis.
Author: Kim, Sun Young|Baek, Ji Yeon|Oh, Jae Hwan|Park, Sung Chan|Sohn, Dae Kyung|Kim, Min Ju|Chang, Hee Jin|Kong, Sun-Young|Kim, Dae Yong
PMID: 28347333
Journal: Biochem Pharmacol. 2018 Mar;149:174-185.
Title: Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells.
Author: Untereiner, Ashley A|Pavlidou, Athanasia|Druzhyna, Nadiya|Papapetropoulos, Andreas|Hellmich, Mark R|Szabo, Csaba
PMID: 29061341