Primary Site >> Colorectal Cancer

Gene >> CYP2A6

  • 2001
  • 2002
  • 2005
  • 2007
  • 2011
  • 2014
  • 2015
  • 2017
  • 2018
Ref: Expression of CYP2A6 in tumor cells augments cellular sensitivity to tegafur.
PMID: 11376561
Ref: CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk.
PMID: 11927498
Ref: Analysis of total meat intake and exposure to individual heterocyclic amines in a case-control study of colorectal cancer: contribution of metabolic variation to risk.
PMID: 12351157
Ref: A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer.
PMID: 12419832
Ref: Novel markers of susceptibility to carcinogens in diet: associations with colorectal cancer.
PMID: 12505289
Ref: A comprehensive analysis of phase I and phase II metabolism gene polymorphisms and risk of colorectal cancer.
PMID: 16006997
Ref: Overexpression of CYP2A6 in human colorectal tumors.
PMID: 17683511
Ref: Associations of various gene polymorphisms with toxicity in colorectal cancer patients receiving oral uracil and tegafur plus leucovorin: a prospective study.
PMID: 20647221
Ref: [Validation of genetic polymorphisms associated to the toxicity of chemotherapy in colorectal cancer patients].
PMID: 25137161
Ref: In-silico structural, virtual screening and docking studies of Human Cytochrome P450 2A7 protein.
PMID: 25519152
Ref: In Silico Structural, Virtual Screening and Docking Studies of Human Cytochrome P450 2A7 Protein.
PMID: 26239541
Ref: A phase II study of preoperative chemoradiation with tegafur-uracil plus leucovorin for locally advanced rectal cancer with pharmacogenetic analysis.
PMID: 28347333
Ref: Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells.
PMID: 29061341