Literatures

Primary Site >> Liver Cancer

Gene >> CYP1A2

1.
Journal:	DNA Cell Biol. 1990 Jul-Aug;9(6):425-36.
Title:	Stable expression of mouse Cyp1a1 and human CYP1A2 cDNAs transfected into mouse hepatoma cells lacking detectable P450 enzyme activity.
Author:	Puga, A\|Raychaudhuri, B\|Salata, K\|Zhang, Y H\|Nebert, D W
PMID:	2206399

2.
Journal:	Hepatology. 1991 Nov;14(5):848-56.
Title:	Localization of CYP1A1 and CYP1A2 messenger RNA in normal human liver and in hepatocellular carcinoma by in situ hybridization.
Author:	McKinnon, R A\|Hall, P D\|Quattrochi, L C\|Tukey, R H\|McManus, M E
PMID:	1657755

3.
Journal:	Carcinogenesis. 1995 Jul;16(7):1549-55.
Title:	Cytochromes P450 in cynomolgus monkeys mutagenically activate 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) but not 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx).
Author:	Sadrieh, N\|Snyderwine, E G
PMID:	7614688

4.
Journal:	Eur J Biochem. 1996 Jun 1;238(2):400-9.
Title:	trans-Acting factors, detoxication enzymes and hepatitis B virus replication in a novel set of human hepatoma cell lines.
Author:	Le Jossic, C\|Glaise, D\|Corcos, L\|Diot, C\|Dezier, J F\|Fautrel, A\|Guguen-Guillouzo, C
PMID:	8681951

5.
Journal:	Pharmacol Ther. 1996;71(1-2):83-105.
Title:	2-Acetylaminofluorene mechanistic data and risk assessment: DNA reactivity, enhanced cell proliferation and tumor initiation.
Author:	Verna, L\|Whysner, J\|Williams, G M
PMID:	8910950

6.
Journal:	Mutat Res. 1997 May 12;376(1-2):203-10.
Title:	Metabolism of food-derived heterocyclic amines in nonhuman primates.
Author:	Snyderwine, E G\|Turesky, R J\|Turteltaub, K W\|Davis, C D\|Sadrieh, N\|Schut, H A\|Nagao, M\|Sugimura, T\|Thorgeirsson, U P\|Adamson, R H\|Thorgeirsson, S S
PMID:	9202757

7.
Journal:	Carcinogenesis. 1997 Jul;18(7):1291-7.
Title:	Aflatoxin B1-induced DNA adduct formation and p53 mutations in CYP450-expressing human liver cell lines.
Author:	Mace, K\|Aguilar, F\|Wang, J S\|Vautravers, P\|Gomez-Lechon, M\|Gonzalez, F J\|Groopman, J\|Harris, C C\|Pfeifer, A M
PMID:	9230270

8.
Journal:	Carcinogenesis. 1997 Nov;18(11):2179-90.
Title:	Distinct time courses of increase in cytochromes P450 1A2, 2A5 and glutathione S-transferases during the progressive hepatitis associated with Helicobacter hepaticus.
Author:	Chomarat, P\|Sipowicz, M A\|Diwan, B A\|Fornwald, L W\|Awasthi, Y C\|Anver, M R\|Rice, J M\|Anderson, L M\|Wild, C P
PMID:	9395219

9.
Journal:	Environ Health Perspect. 1998 Feb;106 Suppl 1:349-55.
Title:	The use of biochemical and molecular parameters to estimate dose-response relationships at low levels of exposure.
Author:	Andersen, M E\|Barton, H A
PMID:	9539029

10.
Journal:	Biochem Pharmacol. 1999 Apr 15;57(8):951-4.
Title:	Decrease in hepatic cytochrome P450 after interleukin-2 immunotherapy.
Author:	Elkahwaji, J\|Robin, M A\|Berson, A\|Tinel, M\|Letteron, P\|Labbe, G\|Beaune, P\|Elias, D\|Rougier, P\|Escudier, B\|Duvillard, P\|Pessayre, D
PMID:	10086330

11.
Journal:	Carcinogenesis. 1999 Sep;20(9):1825-30.
Title:	CYP1A2 is not the primary enzyme responsible for 4-aminobiphenyl-induced hepatocarcinogenesis in mice.
Author:	Kimura, S\|Kawabe, M\|Ward, J M\|Morishima, H\|Kadlubar, F F\|Hammons, G J\|Fernandez-Salguero, P\|Gonzalez, F J
PMID:	10469630

12.
Journal:	Mol Pharmacol. 1999 Oct;56(4):760-7.
Title:	Inhibition of aryl hydrocarbon-induced cytochrome P-450 1A1 enzyme activity and CYP1A1 expression by resveratrol.
Author:	Ciolino, H P\|Yeh, G C
PMID:	10496959

13.
Journal:	Chem Biol Interact. 2000 Nov 1;128(3):211-29.
Title:	Comparative studies on the effects of green tea extracts and individual tea catechins on human CYP1A gene expression.
Author:	Williams, S N\|Shih, H\|Guenette, D K\|Brackney, W\|Denison, M S\|Pickwell, G V\|Quattrochi, L C
PMID:	11064004

14.
Journal:	Ann N Y Acad Sci. 2000;922:260-73.
Title:	DX-8951f: summary of phase I clinical trials.
Author:	De Jager, R\|Cheverton, P\|Tamanoi, K\|Coyle, J\|Ducharme, M\|Sakamoto, N\|Satomi, M\|Suzuki, M
PMID:	11193901

15.
Journal:	Pharmacogenetics. 2001 Jul;11(5):429-35.
Title:	Plasma caffeine metabolite ratio (17X/137X) in vivo associated with G-2964A and C734A polymorphisms of human CYP1A2.
Author:	Han, X M\|Ou-Yang, D S\|Lu, P X\|Jiang, C H\|Shu, Y\|Chen, X P\|Tan, Z R\|Zhou, H H
PMID:	11470995

16.
Journal:	Biochem Cell Biol. 2002;80(1):131-6.
Title:	Cancer prevention by bovine lactoferrin and underlying mechanisms--a review of experimental and clinical studies.
Author:	Tsuda, Hiroyuki\|Sekine, Kazunori\|Fujita, Ken-ichi\|Ligo, Masaaki
PMID:	11908637

17.
Journal:	Arch Toxicol. 2002 Jun;76(5-6):287-98.
Title:	Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences.
Author:	Iwanari, Masashi\|Nakajima, Miki\|Kizu, Ryoichi\|Hayakawa, Kazuichi\|Yokoi, Tsuyoshi
PMID:	12107646

18.
Journal:	Biochem Biophys Res Commun. 2002 Aug 9;296(1):172-7.
Title:	Characterization of human CYP1A1/1A2 induction by DNA microarray and alpha-naphthoflavone.
Author:	Ishida, Seiichi\|Jinno, Hideto\|Tanaka-Kagawa, Toshiko\|Ando, Masanori\|Ohno, Yasuo\|Ozawa, Shogo\|Sawada, Jun ichi
PMID:	12147246

19.
Journal:	Environ Toxicol Pharmacol. 2002 Aug;12(1):1-6.
Title:	Induction of P-glycoprotein, glutathione-S-transferase and cytochrome P450 in rat liver by atrazine.
Author:	Islam, M Omedul\|Hara, Masayuki\|Miyake, Jun
PMID:	21782617

20.
Journal:	Int J Cancer. 2003 Apr 10;104(3):310-7.
Title:	CYP enzyme polymorphisms and susceptibility to HCV-related chronic liver disease and liver cancer.
Author:	Silvestri, Laura\|Sonzogni, Laura\|De Silvestri, Annalisa\|Gritti, Chiara\|Foti, Luciana\|Zavaglia, Claudio\|Leveri, Michela\|Cividini, Agostino\|Mondelli, Mario U\|Civardi, Emilio\|Silini, Enrico M
PMID:	12569554

21.
Journal:	Curr Drug Metab. 2004 Jun;5(3):211-24.
Title:	Cytochrome P450 gene polymorphism and cancer.
Author:	Agundez, Jose A G
PMID:	15180491

22.
Journal:	J Gastroenterol Hepatol. 2005 Aug;20(8):1191-7.
Title:	Genetic polymorphisms of cytochrome P450 in patients with hepatitis C virus-associated hepatocellular carcinoma.
Author:	Mochizuki, Junko\|Murakami, Shigeto\|Sanjo, Akira\|Takagi, Ichiro\|Akizuki, Setsuko\|Ohnishi, Akihiro
PMID:	16048566

23.
Journal:	Drug Metab Dispos. 2006 Jan;34(1):75-83.
Title:	Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells.
Author:	Aninat, Caroline\|Piton, Amelie\|Glaise, Denise\|Le Charpentier, Typhen\|Langouet, Sophie\|Morel, Fabrice\|Guguen-Guillouzo, Christiane\|Guillouzo, Andre
PMID:	16204462

24.
Journal:	Natl Toxicol Program Tech Rep Ser. 2006 Aug;(530):1-258.
Title:	Toxicology and carcinogenesis studies of a binary mixture of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (Cas No. 57465-28-8) and 2,2',4,4',5,5'-hexachlorobiphenyl (PCB 153) (CAS No. 35065-27-1) in female Harlan Sprague-Dawley rats (gavage studies).
Author:
PMID:	17160104

25.
Journal:	Natl Toxicol Program Tech Rep Ser. 2006 Nov;(531):1-218.
Title:	Toxicology and carcinogenesis studies of a binary mixture of 3,3',4,4',5-pentachlorobiphenyl (PCB 126) (Cas No. 57465-28-8) and 2,3',4,4',5-pentachlorobiphenyl (PCB 118) (Cas No. 31508-00-6) in female Harlan Sprague-Dawley rats (gavage studies).
Author:
PMID:	17342196

26.
Journal:	Chem Biol Interact. 2007 May 20;168(1):66-73.
Title:	The human hepatoma HepaRG cells: a highly differentiated model for studies of liver metabolism and toxicity of xenobiotics.
Author:	Guillouzo, Andre\|Corlu, Anne\|Aninat, Caroline\|Glaise, Denise\|Morel, Fabrice\|Guguen-Guillouzo, Christiane
PMID:	17241619

27.
Journal:	Toxicol In Vitro. 2008 Mar;22(2):318-27.
Title:	Antigenotoxic effect of Xanthohumol in rat liver slices.
Author:	Plazar, Janja\|Filipic, Metka\|Groothuis, Geny M M
PMID:	17981005

28.
Journal:	Food Chem Toxicol. 2008 Apr;46(4):1230-8.
Title:	Effects of coffee and its chemopreventive components kahweol and cafestol on cytochrome P450 and sulfotransferase in rat liver.
Author:	Huber, Wolfgang W\|Rossmanith, Walter\|Grusch, Michael\|Haslinger, Elisabeth\|Prustomersky, Sonja\|Peter-Vorosmarty, Barbara\|Parzefall, Wolfram\|Scharf, Gerlinde\|Schulte-Hermann, Rolf
PMID:	17983700

29.
Journal:	J Clin Pharm Ther. 2008 Oct;33(5):489-93.
Title:	The effect of transcatheter arterial chemoembolization on CYP1A2 activity in patients with hepatocellular carcinoma.
Author:	Huang, W\|Qu, Z-Q\|Li, X-D\|He, P\|Ding, N\|Zhang, S-L\|Wu, M C
PMID:	18834363

30.
Journal:	Toxicol Sci. 2009 Jul;110(1):61-7.
Title:	Resveratrol inhibits dioxin-induced expression of human CYP1A1 and CYP1B1 by inhibiting recruitment of the aryl hydrocarbon receptor complex and RNA polymerase II to the regulatory regions of the corresponding genes.
Author:	Beedanagari, Sudheer R\|Bebenek, Ilona\|Bui, Peter\|Hankinson, Oliver
PMID:	19376845

31.
Journal:	Environ Toxicol Pharmacol. 2009 Nov;28(3):370-8.
Title:	The inducibility of human cytochrome P450 1A by environmental-relevant xenobiotics in the human hepatoma derived cell line HepG2.
Author:	Rudzok, Susanne\|Schmucking, Eike\|Graebsch, Carolin\|Herbarth, Olf\|Bauer, Mario
PMID:	21784029

32.
Journal:	Carcinogenesis. 2009 Oct;30(10):1729-34.
Title:	Interaction between cytochrome P450 1A2 genetic polymorphism and cigarette smoking on the risk of hepatocellular carcinoma in a Japanese population.
Author:	Imaizumi, Takeshi\|Higaki, Yasuki\|Hara, Megumi\|Sakamoto, Tatsuhiko\|Horita, Mikako\|Mizuta, Toshihiko\|Eguchi, Yuichiro\|Yasutake, Tsutomu\|Ozaki, Iwata\|Yamamoto, Kyosuke\|Onohara, Shingo\|Kawazoe, Seiji\|Shigematsu, Hirohisa\|Koizumi, Shunzo\|Kudo, Sho\|Tanaka, Keit
PMID:	19643819

33.
Journal:	J Toxicol Sci. 2010 Feb;35(1):69-78.
Title:	The threshold dose for liver tumor promoting effects of dicyclanil in ICR mice.
Author:	Jin, Meilan\|Dewa, Yasuaki\|Kawai, Masaomi\|Nishimura, Jihei\|Saegusa, Yukie\|Kemmochi, Sayaka\|Harada, Tomoaki\|Shibutani, Makoto\|Mitsumori, Kunitoshi
PMID:	20118626

34.
Journal:	Natl Toxicol Program Tech Rep Ser. 2010 Nov;(559):1-174.
Title:	Toxicology and carcinogenesis studies of 2,3',4,4',5-pentachlorobiphenyl (PCB 118) (CAS No. 31508-00-6) in female harlan Sprague-Dawley rats (gavage studies).
Author:
PMID:	21383778

35.
Journal:	Oncol Lett. 2010 Jan;1(1):137-142.
Title:	Tumorigenesis of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), but not enhancing effects of concomitant high-fat diet, on lung carcinogenesis in female A/J mice.
Author:	Takeuchi, Hijiri\|Saoo, Kousuke\|Yamakawa, Keiko\|Matsuda, Yoko\|Yokohira, Masanao\|Zeng, Yu\|Kuno, Totshiya\|Totsuka, Yukari\|Takahashi, Mami\|Wakabayashi, Keiji\|Imaida, Katsumi
PMID:	22966271

36.
Journal:	J Toxicol Sci. 2011 Oct;36(5):625-33.
Title:	Expression of albumin and cytochrome P450 enzymes in HepG2 cells cultured with a nanotechnology-based culture plate with microfabricated scaffold.
Author:	Nakamura, Kazuaki\|Kato, Natsuko\|Aizawa, Kazuko\|Mizutani, Reiko\|Yamauchi, Junji\|Tanoue, Akito
PMID:	22008537

37.
Journal:	Hepatology. 2011 Oct;54(4):1273-81.
Title:	Oxidative stress pathways in noncancerous human liver tissue to predict hepatocellular carcinoma recurrence: a prospective, multicenter study.
Author:	Tanaka, Shinji\|Mogushi, Kaoru\|Yasen, Mahmut\|Ban, Daisuke\|Noguchi, Norio\|Irie, Takumi\|Kudo, Atsushi\|Nakamura, Noriaki\|Tanaka, Hiroshi\|Yamamoto, Masakazu\|Kokudo, Norihiro\|Takayama, Tadatoshi\|Kawasaki, Seiji\|Sakamoto, Michiie\|Arii, Shigeki
PMID:	22006857

38.
Journal:	Toxicology. 2011 May 10;283(2-3):109-17.
Title:	Indole-3-carbinol enhances oxidative stress responses resulting in the induction of preneoplastic liver cell lesions in partially hepatectomized rats initiated with diethylnitrosamine.
Author:	Shimamoto, Keisuke\|Dewa, Yasuaki\|Ishii, Yuji\|Kemmochi, Sayaka\|Taniai, Eriko\|Hayashi, Hitomi\|Imaoka, Masako\|Morita, Reiko\|Kuwata, Kazunori\|Suzuki, Kazuhiko\|Shibutani, Makoto\|Mitsumori, Kunitoshi
PMID:	21396975

39.
Journal:	Vet Pathol. 2011 Jul;48(4):875-84.
Title:	Gene expression and mutation assessment provide clues of genetic and epigenetic mechanisms in liver tumors of oxazepam-exposed mice.
Author:	Lahousse, S A\|Hoenerhoff, M\|Collins, J\|Ton, T-V T\|Masinde, T\|Olson, D\|Rebolloso, Y\|Koujitani, T\|Tomer, K B\|Hong, H-H L\|Bucher, J\|Sills, R C
PMID:	21147764

40.
Journal:	Arch Toxicol. 2011 Dec;85(12):1617-26.
Title:	Genotoxic effects of the cyanobacterial hepatotoxin cylindrospermopsin in the HepG2 cell line.
Author:	Straser, Alja\|Filipic, Metka\|Zegura, Bojana
PMID:	21607682

41.
Journal:	Int J Cancer. 2011 Feb 1;128(3):511-23.
Title:	Higher susceptibility to aflatoxin B(1)-related hepatocellular carcinoma in glycine N-methyltransferase knockout mice.
Author:	Liu, Shih-Ping\|Li, Ying-Shiuan\|Lee, Cheng-Ming\|Yen, Chia-Hung\|Liao, Yi-Jen\|Huang, Shiu-Feng\|Chien, Chau-Heng\|Chen, Yi-Ming Arthur
PMID:	20473876

42.
Journal:	Toxicol Pathol. 2012 Apr;40(3):466-72.
Title:	Cancer prevention mediated by caffeic acid phenethyl ester involves cyp2b1/2 modulation in hepatocarcinogenesis.
Author:	Beltran-Ramirez, Olga\|Perez, Roberto Macias\|Sierra-Santoyo, Adolfo\|Villa-Trevino, Saul
PMID:	22291063

43.
Journal:	Drug Metab Pharmacokinet. 2012;27(5):478-85. Epub 2012 Mar 6.
Title:	Increased expression of drug-metabolizing enzymes in human hepatocarcinoma FLC-4 cells cultured on micro-space cell culture plates.
Author:	Kobayashi, Kaoru\|Yoshida, Akane\|Ejiri, Yoko\|Takagi, Sachiko\|Mimura, Hanaka\|Hosoda, Masaya\|Matsuura, Tomokazu\|Chiba, Kan
PMID:	22447115

44.
Journal:	Environ Mol Mutagen. 2012 Jun;53(5):350-7.
Title:	Influence of arylamine N-acetyltransferase, sex, and age on 4-aminobiphenyl-induced in vivo mutant frequencies and spectra in mouse liver.
Author:	Wang, Shuang\|Sugamori, Kim S\|Brenneman, Debbie\|Hsu, Ivy\|Calce, Adriana\|Grant, Denis M
PMID:	22508569

45.
Journal:	Toxicology. 2012 Sep 28;299(2-3):69-79.
Title:	Dietary modulation of the biotransformation and genotoxicity of aflatoxin B(1).
Author:	Gross-Steinmeyer, Kerstin\|Eaton, David L
PMID:	22640941

46.
Journal:	J Toxicol Sci. 2012;37(3):491-501.
Title:	Liver tumor promoting effect of omeprazole in rats and its possible mechanism of action.
Author:	Hayashi, Hitomi\|Shimamoto, Keisuke\|Taniai, Eriko\|Ishii, Yuji\|Morita, Reiko\|Suzuki, Kazuhiko\|Shibutani, Makoto\|Mitsumori, Kunitoshi
PMID:	22687989

47.
Journal:	J Toxicol Sci. 2012;37(3):517-26.
Title:	Threshold dose of liver tumor promoting effect of beta-naphthoflavone in rats.
Author:	Hayashi, Hitomi\|Taniai, Eriko\|Morita, Reiko\|Yafune, Atsunori\|Suzuki, Kazuhiko\|Shibutani, Makoto\|Mitsumori, Kunitoshi
PMID:	22687991

48.
Journal:	Asian Pac J Cancer Prev. 2012;13 Suppl:7-15.
Title:	Genetic polymorphism of drug metabolizing enzymes in association with risk of bile duct cancer.
Author:	Kukongviriyapan, Veerapol
PMID:	23480767

49.
Journal:	Arch Toxicol. 2013 Jun;87(6):1001-12.
Title:	Inhibition of hepatocyte nuclear factor 1 and 4 alpha (HNF1alpha and HNF4alpha) as a mechanism of arsenic carcinogenesis.
Author:	Pastoret, Anna\|Marcos, Ricard\|Sampayo-Reyes, Adriana\|Saucedo-Cardenas, Odila\|Lozano-Garza, Gerardo H\|Hernandez, Alba
PMID:	23052196

50.
Journal:	J Ethnopharmacol. 2014;151(1):210-7.
Title:	Marsdenia tenacissima extract inhibits gefitinib metabolism in vitro by interfering with human hepatic CYP3A4 and CYP2D6 enzymes.
Author:	Han, Shu-Yan\|Zhao, Hai-Yu\|Zhou, Ning\|Zhou, Fei\|Li, Ping-Ping
PMID:	24157377

51.
Journal:	Xenobiotica. 2014 Jul;44(7):606-14.
Title:	In vitro inhibition of human liver cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT) enzymes by rose bengal: system-dependent effects on inhibitory potential.
Author:	Kazmi, Faraz\|Haupt, Lois J\|Horkman, Jennifer R\|Smith, Brian D\|Buckley, David B\|Wachter, Eric A\|Singer, Jamie M
PMID:	24405273

52.
Journal:	Cell Physiol Biochem. 2014;33(5):1400-10.
Title:	Short-term effects of oral administration of Pistacia lentiscus oil on tissue-specific toxicity and drug metabolizing enzymes in mice.
Author:	Attoub, Samir\|Karam, Sherif M\|Nemmar, Abderrahim\|Arafat, Kholoud\|John, Annie\|Al-Dhaheri, Wafa\|Al Sultan, Mahmood Ahmed\|Raza, Haider
PMID:	24853661

53.
Journal:	World J Gastroenterol. 2014 Jul 14;20(26):8681-90.
Title:	Expression of P450 and nuclear receptors in normal and end-stage Chinese livers.
Author:	Chen, Hong\|Shen, Zhong-Yang\|Xu, Wang\|Fan, Tie-Yan\|Li, Jun\|Lu, Yuan-Fu\|Cheng, Ming-Liang\|Liu, Jie
PMID:	25024626

54.
Journal:	Drug Metab Pharmacokinet. 2015 Dec;30(6):434-40.
Title:	CYP1A1 and CYP1A2 expression levels are differentially regulated in three-dimensional spheroids of liver cancer cells compared to two-dimensional monolayer cultures.
Author:	Terashima, Jun\|Goto, Shinpei\|Hattori, Hiroki\|Hoshi, Sawaka\|Ushirokawa, Midori\|Kudo, Kenzo\|Habano, Wataru\|Ozawa, Shogo
PMID:	26643992

55.
Journal:	BMC Syst Biol. 2015 Nov 20;9:83.
Title:	Pathobiochemical signatures of cholestatic liver disease in bile duct ligated mice.
Author:	Abshagen, Kerstin\|Konig, Matthias\|Hoppe, Andreas\|Muller, Isabell\|Ebert, Matthias\|Weng, Honglei\|Holzhutter, Herrmann-Georg\|Zanger, Ulrich M\|Bode, Johannes\|Vollmar, Brigitte\|Thomas, Maria\|Dooley, Steven
PMID:	26589287

56.
Journal:	Mol Cancer Ther. 2015 Dec;14(12):2874-86.
Title:	Severely Impaired and Dysregulated Cytochrome P450 Expression and Activities in Hepatocellular Carcinoma: Implications for Personalized Treatment in Patients.
Author:	Yan, Tongmeng\|Lu, Linlin\|Xie, Cong\|Chen, Jiamei\|Peng, Xiaojuan\|Zhu, Lijun\|Wang, Ying\|Li, Qiang\|Shi, Jian\|Zhou, Fuyuan\|Hu, Ming\|Liu, Zhongqiu
PMID:	26516155

57.
Journal:	Toxicol Sci. 2015 Oct;147(2):549-61.
Title:	Mechanistic Investigation of Toxaphene Induced Mouse Liver Tumors.
Author:	Wang, Zemin\|Neal, Barbara H\|Lamb, James C\|Klaunig, James E
PMID:	26187448

58.
Journal:	Drug Metab Dispos. 2015 Jul;43(7):916-21.
Title:	Relative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult Mice.
Author:	Wang, Shuang\|Bott, Debbie\|Tung, Aveline\|Sugamori, Kim S\|Grant, Denis M
PMID:	25922528

59.
Journal:	Toxicol Sci. 2015 Apr;144(2):393-405.
Title:	N-hydroxylation of 4-aminobiphenyl by CYP2E1 produces oxidative stress in a mouse model of chemically induced liver cancer.
Author:	Wang, Shuang\|Sugamori, Kim S\|Tung, Aveline\|McPherson, J Peter\|Grant, Denis M
PMID:	25601990

60.
Journal:	Mater Sci Eng C Mater Biol Appl. 2015 Jan;46:190-4.
Title:	A novel effect of parylene-based surface coating on HepG2 cell function.
Author:	Tozawa, Hideto\|Maekawa, Toshiro\|Kimura, Hiroshi\|Fujii, Teruo
PMID:	25491976

61.
Journal:	Adv Pharmacol. 2015;74:85-111.
Title:	Polymorphic Variants of Cytochrome P450: Relevance to Cancer and Other Diseases.
Author:	Daly, Ann K
PMID:	26233904

62.
Journal:	Springerplus. 2016 Apr 6;5:413.
Title:	Root extract of water dropwort, Oenanthe javanica (Blume) DC, induces protein and gene expression of phase I carcinogen-metabolizing enzymes in HepG2 cells.
Author:	Kim, Jae Kyeom\|Shin, Eui-Cheol\|Park, Gwi Gun\|Kim, Youn-Jung\|Shin, Dong-Hoon
PMID:	27069833

63.
Journal:	Oncotarget. 2016 May 10;7(19):28612-23.
Title:	Changes in cytochrome P450s-mediated drug clearance in patients with hepatocellular carcinoma in vitro and in vivo: a bottom-up approach.
Author:	Gao, Jie\|Zhou, Jun\|He, Xiao-Pei\|Zhang, Yun-Fei\|Gao, Na\|Tian, Xin\|Fang, Yan\|Wen, Qiang\|Jia, Lin-Jing\|Jin, Han\|Qiao, Hai-Ling
PMID:	27086920

64.
Journal:	PLoS One. 2016 Apr 19;11(4):e0153863.
Title:	Cytochrome P450 1A2 Metabolizes 17beta-Estradiol to Suppress Hepatocellular Carcinoma.
Author:	Ren, Jianwai\|Chen, George G\|Liu, Yi\|Su, Xianwei\|Hu, Baoguang\|Leung, Billy C S\|Wang, Y\|Ho, Rocky L K\|Yang, Shengli\|Lu, Gang\|Lee, C G\|Lai, Paul B S
PMID:	27093553

65.
Journal:	Oncotarget. 2016 Aug 2;7(31):50612-50623.
Title:	Significant change of cytochrome P450s activities in patients with hepatocellular carcinoma.
Author:	Zhou, Jun\|Wen, Qiang\|Li, Sai-Fei\|Zhang, Yun-Fei\|Gao, Na\|Tian, Xin\|Fang, Yan\|Gao, Jie\|Cui, Ming-Zhu\|He, Xiao-Pei\|Jia, Lin-Jing\|Jin, Han\|Qiao, Hai-Ling
PMID:	27203676

66.
Journal:	Protein Pept Lett. 2017 May 10;24(5):406-412.
Title:	Diosmetin Induces Cell Apoptosis by Regulating CYP1A1/CYP1A2 Due to p53 Activation in HepG2 Cells.
Author:	Liu, Bin\|Jia, Kaiqiao\|Yang, Yu\|Hao, Siyuan\|Lu, Caijie\|Xu, Fengming\|Feng, Dehui\|Zhu, Runzhi
PMID:	28245756

67.
Journal:	Biochem J. 2017 Sep 28;474(20):3391-3402.
Title:	Carbidopa is an activator of aryl hydrocarbon receptor with potential for cancer therapy.
Author:	Ogura, Jiro\|Miyauchi, Seiji\|Shimono, Kazumi\|Yang, Shengping\|Gonchigar, Sathisha\|Ganapathy, Vadivel\|Bhutia, Yangzom D
PMID:	28963435

68.
Journal:	Oncotarget. 2017 Jul 6;8(34):57109-57120.
Title:	Oxidative stress mediates an increased formation of vascular endothelial growth factor in human hepatocarcinoma cells exposed to erlotinib.
Author:	Rohr-Udilova, Nataliya\|Klinglmuller, Florian\|Seif, Martha\|Hayden, Hubert\|Bilban, Martin\|Pinter, Matthias\|Stolze, Klaus\|Sieghart, Wolfgang\|Peck-Radosavljevic, Markus\|Trauner, Michael
PMID:	28915658

69.
Journal:	Carcinogenesis. 2017 Jul 1;38(7):717-727.
Title:	Characterization of liver injury, oval cell proliferation and cholangiocarcinogenesis in glutathione S-transferase A3 knockout mice.
Author:	Crawford, Dana R\|Ilic, Zoran\|Guest, Ian\|Milne, Ginger L\|Hayes, John D\|Sell, Stewart
PMID:	28535182

70.
Journal:	Food Chem Toxicol. 2017 May;103:122-132.
Title:	Hydroxystilbenes and methoxystilbenes activate human aryl hydrocarbon receptor and induce CYP1A genes in human hepatoma cells and human hepatocytes.
Author:	Pastorkova, Barbora\|Vrzalova, Aneta\|Bachleda, Petr\|Dvorak, Zdenek
PMID:	28279696

71.
Journal:	Basic Clin Pharmacol Toxicol. 2017 Oct;121(4):334-341.
Title:	Cis-Nerolidol Induces Endoplasmic Reticulum Stress and Cell Death in Human Hepatocellular Carcinoma Cells through Extensive CYP2C19 and CYP1A2 Oxidation.
Author:	Biazi, Bruna Isabela\|Zanetti, Thalita Alves\|Baranoski, Adrivanio\|Corveloni, Amanda Cristina\|Mantovani, Mario Sergio
PMID:	28256105

72.
Journal:	Xenobiotica. 2018 Nov;48(11):1164-1172.
Title:	Identification and analysis of the reactive metabolites related to the hepatotoxicity of safrole.
Author:	Yang, Ai-Hong\|Zhang, Lei\|Zhi, De-Xian\|Liu, Wen-Li\|Gao, Xue\|He, Xin
PMID:	29082813

73.
Journal:	Biomed Res Int. 2018 Jul 25;2018:5859415.
Title:	Downregulation of CYP2A6 and CYP2C8 in Tumor Tissues Is Linked to Worse Overall Survival and Recurrence-Free Survival from Hepatocellular Carcinoma.
Author:	Ren, Xiaojing\|Ji, Yuanyuan\|Jiang, Xuhua\|Qi, Xun
PMID:	30148168

74.
Journal:	Mol Cell Biol. 2018 Sep 17. pii: MCB.00213-18.
Title:	Induction of hepatic metabolic functions by a novel variant of hepatocyte nuclear factor 4gamma.
Author:	Sasaki, Shota\|Urabe, Mizuho\|Maeda, Tsukasa\|Suzuki, Junko\|Irie, Ryota\|Suzuki, Masanori\|Tomaru, Yasuhiro\|Sakaguchi, Masakiyo\|Gonzalez, Frank J\|Inoue, Yusuke
PMID:	30224520