Literatures

Primary Site >> Pancreatic Cancer

Gene >> CXCR4

1.
Journal:	Clin Cancer Res. 2000 Sep;6(9):3530-5.
Title:	Expression of stromal cell-derived factor 1 and CXCR4 ligand receptor system in pancreatic cancer: a possible role for tumor progression.
Author:	Koshiba, T\|Hosotani, R\|Miyamoto, Y\|Ida, J\|Tsuji, S\|Nakajima, S\|Kawaguchi, M\|Kobayashi, H\|Doi, R\|Hori, T\|Fujii, N\|Imamura, M
PMID:	10999740

2.
Journal:	J Cell Biochem. 2003 Jun 1;89(3):462-73.
Title:	Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo.
Author:	Sun, Yan-Xi\|Wang, Jingcheng\|Shelburne, Charles E\|Lopatin, Dennis E\|Chinnaiyan, Arul M\|Rubin, Mark A\|Pienta, Kenneth J\|Taichman, Russell S
PMID:	12761880

3.
Journal:	Mol Cancer Ther. 2004 Jan;3(1):29-37.
Title:	CXCR4 antagonist inhibits stromal cell-derived factor 1-induced migration and invasion of human pancreatic cancer.
Author:	Mori, Tomohiko\|Doi, Ryuichiro\|Koizumi, Masayuki\|Toyoda, Eiji\|Ito, Daisuke\|Kami, Kazuhiro\|Masui, Toshihiko\|Fujimoto, Koji\|Tamamura, Hirokazu\|Hiramatsu, Kenichi\|Fujii, Nobutaka\|Imamura, Masayuki
PMID:	14749473

4.
Journal:	Gan To Kagaku Ryoho. 2004 Aug;31(8):1261-3.
Title:	[mRNA expression of chemokine receptors in hepatic and pancreatic tumor cell lines].
Author:	Masai, Kyohei\|Iwashita, Yukio\|Tominaga, Masayuki\|Hirano, Seitaro\|Shibata, Kohei\|Matsumoto, Toshifumi\|Sasaki, Atsushi\|Ohta, Masayuki\|Kitano, Seigo
PMID:	15332556

5.
Journal:	Cancer Res. 2004 Nov 15;64(22):8420-7.
Title:	Increased survival, proliferation, and migration in metastatic human pancreatic tumor cells expressing functional CXCR4.
Author:	Marchesi, Federica\|Monti, Paolo\|Leone, Biagio Eugenio\|Zerbi, Alessandro\|Vecchi, Annunciata\|Piemonti, Lorenzo\|Mantovani, Alberto\|Allavena, Paola
PMID:	15548713

6.
Journal:	Cancer Biol Ther. 2005 Jan;4(1):70-6. Epub 2005 Jan 15.
Title:	The chemokine receptor CXCR4 is regulated by DNA methylation in pancreatic cancer.
Author:	Sato, Norihiro\|Matsubayashi, Hiroyuki\|Fukushima, Noriyoshi\|Goggins, Michael
PMID:	15662133

7.
Journal:	Cancer Lett. 2005 Jul 28;225(2):261-6. Epub 2004 Dec 13.
Title:	Stromal cell-derived factor-1 (SDF-1) alleles and susceptibility to breast carcinoma.
Author:	Razmkhah, Mahboobeh\|Talei, Abdul-Rasoul\|Doroudchi, Mehrnoosh\|Khalili-Azad, Tahereh\|Ghaderi, Abbas
PMID:	15978329

8.
Journal:	Gastroenterology. 2005 Oct;129(4):1237-50.
Title:	CXCR4 expression increases liver and lung metastasis in a mouse model of pancreatic cancer.
Author:	Saur, Dieter\|Seidler, Barbara\|Schneider, Gunter\|Algul, Hana\|Beck, Roswitha\|Senekowitsch-Schmidtke, Reingard\|Schwaiger, Markus\|Schmid, Roland M
PMID:	16230077

9.
Journal:	Expert Opin Ther Targets. 2005 Dec;9(6):1267-82.
Title:	The therapeutic potential of CXCR4 antagonists in the treatment of HIV infection, cancer metastasis and rheumatoid arthritis.
Author:	Tamamura, Hirokazu\|Fujii, Nobutaka
PMID:	16300475

10.
Journal:	Cancer. 2006 Jul 15;107(2):251-7.
Title:	Aberrant methylation of Reprimo correlates with genetic instability and predicts poor prognosis in pancreatic ductal adenocarcinoma.
Author:	Sato, Norihiro\|Fukushima, Noriyoshi\|Matsubayashi, Hiroyuki\|Iacobuzio-Donahue, Christine A\|Yeo, Charles J\|Goggins, Michael
PMID:	16752411

11.
Journal:	Cancer Biol Ther. 2006 Oct;5(10):1383-9. Epub 2006 Oct 22.
Title:	Differentiating pancreatic lesions by microarray and QPCR analysis of pancreatic juice RNAs.
Author:	Rogers, Carmelle D\|Fukushima, Noriyoshi\|Sato, Norihiro\|Shi, Chanjuan\|Prasad, Nijaguna\|Hustinx, Steven R\|Matsubayashi, Hiroyuki\|Canto, Marcia\|Eshleman, James R\|Hruban, Ralph H\|Goggins, Michael
PMID:	17012836

12.
Journal:	Oncol Rep. 2006 Dec;16(6):1159-64.
Title:	Strong expression of chemokine receptor CXCR4 by pancreatic cancer correlates with advanced disease.
Author:	Wehler, Thomas\|Wolfert, Felix\|Schimanski, Carl C\|Gockel, Ines\|Herr, Wolfgang\|Biesterfeld, Stefan\|Seifert, Joachim K\|Adwan, Hassan\|Berger, Martin R\|Junginger, Theodor\|Galle, Peter R\|Moehler, Markus
PMID:	17089032

13.
Journal:	Int J Gastrointest Cancer. 2006;37(4):110-9.
Title:	Characterization of the CXCR4 signaling in pancreatic cancer cells.
Author:	Billadeau, Daniel D\|Chatterjee, Subrha\|Bramati, Patricia\|Sreekumar, Raghavakaimal\|Shah, Vijay\|Hedin, Karen\|Urrutia, Raul
PMID:	18175225

14.
Journal:	Med Hypotheses. 2007;69(4):816-20. Epub 2007 Mar 26.
Title:	Beta-catenin is a promising key factor in the SDF-1/CXCR4 axis on metastasis of pancreatic cancer.
Author:	Wang, Zheng\|Ma, Qingyong
PMID:	17379424

15.
Journal:	Surgery. 2007 Jun;141(6):804-14. Epub 2007 May 4.
Title:	Integrin-mediated laminin-1 adhesion upregulates CXCR4 and IL-8 expression in pancreatic cancer cells.
Author:	Grzesiak, John J\|Smith, Kathy C\|Burton, Douglas W\|Deftos, Leonard J\|Bouvet, Michael
PMID:	17560257

16.
Journal:	Cell Stem Cell. 2007 Sep 13;1(3):313-23.
Title:	Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer.
Author:	Hermann, Patrick C\|Huber, Stephan L\|Herrler, Tanja\|Aicher, Alexandra\|Ellwart, Joachim W\|Guba, Markus\|Bruns, Christiane J\|Heeschen, Christopher
PMID:	18371365

17.
Journal:	Br J Cancer. 2008 Apr 22;98(8):1389-97.
Title:	CD133 expression is correlated with lymph node metastasis and vascular endothelial growth factor-C expression in pancreatic cancer.
Author:	Maeda, S\|Shinchi, H\|Kurahara, H\|Mataki, Y\|Maemura, K\|Sato, M\|Natsugoe, S\|Aikou, T\|Takao, S
PMID:	18349830

18.
Journal:	Gut. 2008 Nov;57(11):1555-60.
Title:	The chemokine receptor CXCR4 is expressed in pancreatic intraepithelial neoplasia.
Author:	Thomas, R M\|Kim, J\|Revelo-Penafiel, M P\|Angel, R\|Dawson, D W\|Lowy, A M
PMID:	18664506

19.
Journal:	Gut. 2008 Oct;57(10):1456-68.
Title:	Recent progress on normal and malignant pancreatic stem/progenitor cell research: therapeutic implications for the treatment of type 1 or 2 diabetes mellitus and aggressive pancreatic cancer.
Author:	Mimeault, M\|Batra, S K
PMID:	18791122

20.
Journal:	Cancer Res. 2008 Nov 1;68(21):8938-44.
Title:	Zerumbone down-regulates chemokine receptor CXCR4 expression leading to inhibition of CXCL12-induced invasion of breast and pancreatic tumor cells.
Author:	Sung, Bokyung\|Jhurani, Sonia\|Ahn, Kwang Seok\|Mastuo, Yoichi\|Yi, Tingfang\|Guha, Sushovan\|Liu, Mingyao\|Aggarwal, Bharat B
PMID:	18974138

21.
Journal:	Br J Cancer. 2008 Nov 18;99(10):1695-703.
Title:	Blockade of SDF-1/CXCR4 signalling inhibits pancreatic cancer progression in vitro via inactivation of canonical Wnt pathway.
Author:	Wang, Z\|Ma, Q\|Liu, Q\|Yu, H\|Zhao, L\|Shen, S\|Yao, J
PMID:	19002187

22.
Journal:	Int J Cancer. 2009 Feb 15;124(4):853-61.
Title:	CXCL8/IL-8 and CXCL12/SDF-1alpha co-operatively promote invasiveness and angiogenesis in pancreatic cancer.
Author:	Matsuo, Yoichi\|Ochi, Nobuo\|Sawai, Hirozumi\|Yasuda, Akira\|Takahashi, Hiroki\|Funahashi, Hitoshi\|Takeyama, Hiromitsu\|Tong, Zhimin\|Guha, Sushovan
PMID:	19035451

23.
Journal:	J Biol Chem. 2009 Feb 6;284(6):3650-62.
Title:	Secreted trefoil factor 2 activates the CXCR4 receptor in epithelial and lymphocytic cancer cell lines.
Author:	Dubeykovskaya, Zinaida\|Dubeykovskiy, Alexander\|Solal-Cohen, Joel\|Wang, Timothy C
PMID:	19064997

24.
Journal:	Zhonghua Zhong Liu Za Zhi. 2009 Apr;31(4):286-7.
Title:	[Expression of CXCL12-CXCR4 and its association with angiogenesis in pancreatic cancer].
Author:	Niu, Zuo-xing\|Fei, Li-ming\|Wang, Chang-liang
PMID:	19615285

25.
Journal:	Oncogene. 2010 Jan 7;29(1):56-67.
Title:	PAUF functions in the metastasis of human pancreatic cancer cells and upregulates CXCR4 expression.
Author:	Lee, Y\|Kim, S J\|Park, H D\|Park, E H\|Huang, S M\|Jeon, S B\|Kim, J-M\|Lim, D-S\|Koh, S S
PMID:	19784070

26.
Journal:	Pancreas. 2010 Jan;39(1):81-7.
Title:	Chemokine receptor CXCR4 enhances proliferation in pancreatic cancer cells through AKT and ERK dependent pathways.
Author:	Shen, Xiaoming\|Artinyan, Avo\|Jackson, Desmond\|Thomas, Ryan M\|Lowy, Andrew M\|Kim, Joseph
PMID:	19820417

27.
Journal:	Biomed Pharmacother. 2010 Apr;64(4):254-8.
Title:	Increased CXCR4 expression in AsPC1 pancreatic carcinoma cells with RNA interference-mediated knockdown of DNMT1 and DNMT3B.
Author:	Przybylski, M\|Kozlowska, A\|Pietkiewicz, P P\|Lutkowska, A\|Lianeri, M\|Jagodzinski, P P
PMID:	19932585

28.
Journal:	Int J Oncol. 2010 Feb;36(2):415-20.
Title:	Integrative genomic analyses of CXCR4: transcriptional regulation of CXCR4 based on TGFbeta, Nodal, Activin signaling and POU5F1, FOXA2, FOXC2, FOXH1, SOX17, and GFI1 transcription factors.
Author:	Katoh, Masuko\|Katoh, Masaru
PMID:	20043076

29.
Journal:	Pancreatology. 2010;10(2-3):186-93.
Title:	Pancreatic stellate cells increase the invasion of human pancreatic cancer cells through the stromal cell-derived factor-1/CXCR4 axis.
Author:	Gao, Zhenjun\|Wang, Xingpeng\|Wu, Kai\|Zhao, Yan\|Hu, Guoyong
PMID:	20484957

30.
Journal:	Cancer. 2010 Jul 15;116(14):3357-68.
Title:	Enhanced cell migration and invasion of CD133+ pancreatic cancer cells cocultured with pancreatic stromal cells.
Author:	Moriyama, Taiki\|Ohuchida, Kenoki\|Mizumoto, Kazuhiro\|Cui, Lin\|Ikenaga, Naoki\|Sato, Norihiro\|Tanaka, Masao
PMID:	20564084

31.
Journal:	Cancer Res. 2010 Aug 1;70(15):6283-92.
Title:	Transplanting normal vascular proangiogenic cells to tumor-bearing mice triggers vascular remodeling and reduces hypoxia in tumors.
Author:	Sasajima, Junpei\|Mizukami, Yusuke\|Sugiyama, Yoshiaki\|Nakamura, Kazumasa\|Kawamoto, Toru\|Koizumi, Kazuya\|Fujii, Rie\|Motomura, Wataru\|Sato, Kazuya\|Suzuki, Yasuaki\|Tanno, Satoshi\|Fujiya, Mikihiro\|Sasaki, Katsunori\|Shimizu, Norihiko\|Karasaki, Hidenori\|Kono, To
PMID:	20631070

32.
Journal:	Biochem Pharmacol. 2010 Nov 15;80(10):1553-62.
Title:	Butein downregulates chemokine receptor CXCR4 expression and function through suppression of NF-kappaB activation in breast and pancreatic tumor cells.
Author:	Chua, Angeline Wei Ling\|Hay, Hui Sin\|Rajendran, Peramaiyan\|Shanmugam, Muthu K\|Li, Feng\|Bist, Pradeep\|Koay, Evelyn S C\|Lim, Lina H K\|Kumar, Alan Prem\|Sethi, Gautam
PMID:	20699088

33.
Journal:	Integr Cancer Ther. 2010 Sep;9(3):291-7.
Title:	The molecular mechanisms of traditional Chinese medicine ZHENG syndromes on pancreatic tumor growth.
Author:	Dai, Hai-Yan\|Wang, Peng\|Feng, Lan-Yun\|Liu, Lu-Ming\|Meng, Zhi-Qiang\|Zhu, Xiao-Yan\|Wang, Kun\|Hua, Yong-Qiang\|Mao, Yi-Xiang\|Chen, Lian-Yu\|Chen, Zhen
PMID:	20702498

34.
Journal:	Cancer Epidemiol Biomarkers Prev. 2010 Oct;19(10):2598-604.
Title:	High levels of expression of human stromal cell-derived factor-1 are associated with worse prognosis in patients with stage II pancreatic ductal adenocarcinoma.
Author:	Liang, John J\|Zhu, Shaobo\|Bruggeman, Richard\|Zaino, Richard J\|Evans, Douglas B\|Fleming, Jason B\|Gomez, Henry F\|Zander, Dani S\|Wang, Huamin
PMID:	20732965

35.
Journal:	J Mol Med (Berl). 2010 Dec;88(12):1243-53.
Title:	Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor.
Author:	Yadav, Vivek R\|Sung, Bokyung\|Prasad, Sahdeo\|Kannappan, Ramaswamy\|Cho, Sung-Gook\|Liu, Mingyao\|Chaturvedi, Madan M\|Aggarwal, Bharat B
PMID:	20798912

36.
Journal:	Cancer Res. 2010 Nov 1;70(21):8695-705.
Title:	{Gamma}-tocotrienol inhibits pancreatic tumors and sensitizes them to gemcitabine treatment by modulating the inflammatory microenvironment.
Author:	Kunnumakkara, Ajaikumar B\|Sung, Bokyung\|Ravindran, Jayaraj\|Diagaradjane, Parmeswaran\|Deorukhkar, Amit\|Dey, Sanjit\|Koca, Cemile\|Yadav, Vivek R\|Tong, Zhimin\|Gelovani, Juri G\|Guha, Sushovan\|Krishnan, Sunil\|Aggarwal, Bharat B
PMID:	20864511

37.
Journal:	Br J Cancer. 2010 Nov 23;103(11):1671-9.
Title:	CXCL12-CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: a novel target for therapy.
Author:	Singh, S\|Srivastava, S K\|Bhardwaj, A\|Owen, L B\|Singh, A P
PMID:	21045835

38.
Journal:	Biosci Rep. 2011 Feb;31(1):45-55.
Title:	Pancreatic cancer spheres are more than just aggregates of stem marker-positive cells.
Author:	Gaviraghi, Margherita\|Tunici, Patrizia\|Valensin, Silvia\|Rossi, Marco\|Giordano, Cinzia\|Magnoni, Letizia\|Dandrea, Mario\|Montagna, Licia\|Ritelli, Rossana\|Scarpa, Aldo\|Bakker, Annette
PMID:	20426768

39.
Journal:	J Surg Res. 2011 Nov;171(1):143-50.
Title:	The CXCR4-CXCL12 pathway facilitates the progression of pancreatic cancer via induction of angiogenesis and lymphangiogenesis.
Author:	Cui, Kai\|Zhao, Wenhua\|Wang, Changliang\|Wang, Ailiang\|Zhang, Bo\|Zhou, Wuyuan\|Yu, Jinming\|Sun, Ziqiang\|Li, Sheng
PMID:	20462600

40.
Journal:	Int J Cancer. 2011 Jul 1;129(1):23-33.
Title:	Acetyl-11-keto-beta-boswellic acid suppresses invasion of pancreatic cancer cells through the downregulation of CXCR4 chemokine receptor expression.
Author:	Park, Byoungduck\|Sung, Bokyung\|Yadav, Vivek R\|Cho, Sung-Gook\|Liu, Mingyao\|Aggarwal, Bharat B
PMID:	21448932

41.
Journal:	Pathobiology. 2011;78(4):181-92.
Title:	Hypoxia induces tumor aggressiveness and the expansion of CD133-positive cells in a hypoxia-inducible factor-1alpha-dependent manner in pancreatic cancer cells.
Author:	Hashimoto, Okito\|Shimizu, Kazuya\|Semba, Shuho\|Chiba, Sachie\|Ku, Yonson\|Yokozaki, Hiroshi\|Hori, Yuichi
PMID:	21778785

42.
Journal:	PLoS One. 2011;6(8):e23383.
Title:	Holoclone forming cells from pancreatic cancer cells enrich tumor initiating cells and represent a novel model for study of cancer stem cells.
Author:	Tan, Lei\|Sui, Xin\|Deng, Hongkui\|Ding, Mingxiao
PMID:	21826251

43.
Journal:	PLoS One. 2011;6(10):e26943.
Title:	Boswellic acid suppresses growth and metastasis of human pancreatic tumors in an orthotopic nude mouse model through modulation of multiple targets.
Author:	Park, Byoungduck\|Prasad, Sahdeo\|Yadav, Vivek\|Sung, Bokyung\|Aggarwal, Bharat B
PMID:	22066019

44.
Journal:	Oncology. 2011;81(3-4):259-72.
Title:	Molecular pathogenesis of pancreatic cancer and clinical perspectives.
Author:	Matthaios, D\|Zarogoulidis, P\|Balgouranidou, I\|Chatzaki, E\|Kakolyris, S
PMID:	22116519

45.
Journal:	PLoS One. 2011;6(12):e29461.
Title:	Epigenetic changes of CXCR4 and its ligand CXCL12 as prognostic factors for sporadic breast cancer.
Author:	Ramos, Edneia A S\|Grochoski, Mariana\|Braun-Prado, Karin\|Seniski, Gerusa G\|Cavalli, Iglenir J\|Ribeiro, Enilze M S F\|Camargo, Anamaria A\|Costa, Fabricio F\|Klassen, Giseli
PMID:	22220212

46.
Journal:	Cancers (Basel). 2011 Feb 17;3(1):675-99.
Title:	Treatment of pancreatic cancer: what can we really predict today?
Author:	Bachet, Jean-Baptiste\|Marechal, Raphael\|Van Laethem, Jean-Luc
PMID:	24212636

47.
Journal:	Int J Cancer. 2012 Aug 1;131(3):E292-303.
Title:	Zyflamend suppresses growth and sensitizes human pancreatic tumors to gemcitabine in an orthotopic mouse model through modulation of multiple targets.
Author:	Kunnumakkara, Ajaikumar B\|Sung, Bokyung\|Ravindran, Jayaraj\|Diagaradjane, Parmeswaran\|Deorukhkar, Amit\|Dey, Sanjit\|Koca, Cemile\|Tong, Zhimin\|Gelovani, Juri G\|Guha, Sushovan\|Krishnan, Sunil\|Aggarwal, Bharat B
PMID:	21935918

48.
Journal:	EMBO Mol Med. 2012 Mar;4(3):218-33.
Title:	Hedgehog-EGFR cooperation response genes determine the oncogenic phenotype of basal cell carcinoma and tumour-initiating pancreatic cancer cells.
Author:	Eberl, Markus\|Klingler, Stefan\|Mangelberger, Doris\|Loipetzberger, Andrea\|Damhofer, Helene\|Zoidl, Kerstin\|Schnidar, Harald\|Hache, Hendrik\|Bauer, Hans-Christian\|Solca, Flavio\|Hauser-Kronberger, Cornelia\|Ermilov, Alexandre N\|Verhaegen, Monique E\|Bichakjian,
PMID:	22294553

49.
Journal:	PLoS One. 2012;7(2):e31004.
Title:	Identification of anti-malarial compounds as novel antagonists to chemokine receptor CXCR4 in pancreatic cancer cells.
Author:	Kim, Joseph\|Yip, M L Richard\|Shen, Xiaoming\|Li, Hubert\|Hsin, Li-Yu Charlie\|Labarge, Samuel\|Heinrich, Eileen L\|Lee, Wendy\|Lu, Jianming\|Vaidehi, Nagarajan
PMID:	22319600

50.
Journal:	Cancer Lett. 2012 Sep 28;322(2):169-76.
Title:	SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial-mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway.
Author:	Li, Xuqi\|Ma, Qingyong\|Xu, Qinhong\|Liu, Han\|Lei, Jianjun\|Duan, Wanxing\|Bhat, Kruttika\|Wang, Fengfei\|Wu, Erxi\|Wang, Zheng
PMID:	22450749

51.
Journal:	Clin Cancer Res. 2012 May 15;18(10):2838-49.
Title:	Molecular profiling of pancreatic neuroendocrine tumors in sporadic and Von Hippel-Lindau patients.
Author:	Speisky, Daniela\|Duces, Aurelie\|Bieche, Ivan\|Rebours, Vinciane\|Hammel, Pascal\|Sauvanet, Alain\|Richard, Stephane\|Bedossa, Pierre\|Vidaud, Michel\|Murat, Arnaud\|Niccoli, Patricia\|Scoazec, Jean-Yves\|Ruszniewski, Philippe\|Couvelard, Anne
PMID:	22461457

52.
Journal:	J Transl Med. 2012 Apr 2;10:68.
Title:	Chemokine CXCL12 activates dual CXCR4 and CXCR7-mediated signaling pathways in pancreatic cancer cells.
Author:	Heinrich, Eileen L\|Lee, Wendy\|Lu, Jianming\|Lowy, Andrew M\|Kim, Joseph
PMID:	22472349

53.
Journal:	Environ Health Perspect. 2012 Sep;120(9):1265-71.
Title:	Chronic cadmium exposure in vitro causes acquisition of multiple tumor cell characteristics in human pancreatic epithelial cells.
Author:	Qu, Wei\|Tokar, Erik J\|Kim, Andrew J\|Bell, Matthew W\|Waalkes, Michael P
PMID:	22626610

54.
Journal:	Med Mol Morphol. 2012 Jun;45(2):59-65.
Title:	Nestin and other putative cancer stem cell markers in pancreatic cancer.
Author:	Matsuda, Yoko\|Kure, Shoko\|Ishiwata, Toshiyuki
PMID:	22718289

55.
Journal:	Surgery. 2012 Sep;152(3):441-8.
Title:	Virotherapy using a novel chimeric oncolytic adenovirus prolongs survival in a human pancreatic cancer xenograft model.
Author:	Chu, Quyen D\|Sun, Guang\|Pope, Matt\|Luraguiz, Natalia\|Curiel, David T\|Kim, Roger\|Li, Benjamin D L\|Mathis, J Michael
PMID:	22853858

56.
Journal:	Eur Surg Res. 2012;49(2):88-98.
Title:	Pancreatic carcinoma cell lines reflect frequency and variability of cancer stem cell markers in clinical tissue.
Author:	Bunger, S\|Barow, M\|Thorns, C\|Freitag-Wolf, S\|Danner, S\|Tiede, S\|Pries, R\|Gorg, S\|Bruch, H-P\|Roblick, U J\|Kruse, C\|Habermann, J K
PMID:	22948659

57.
Journal:	Neoplasia. 2012 Aug;14(8):690-701.
Title:	Stromal cell-derived factor 1alpha mediates resistance to mTOR-directed therapy in pancreatic cancer.
Author:	Weekes, Colin D\|Song, Dongweon\|Arcaroli, John\|Wilson, Lora A\|Rubio-Viqueira, Belen\|Cusatis, George\|Garrett-Mayer, Elizabeth\|Messersmith, Wells A\|Winn, Robert A\|Hidalgo, Manuel
PMID:	22952422

58.
Journal:	Stem Cell Res. 2012 Nov;9(3):249-60.
Title:	Comparative testing of various pancreatic cancer stem cells results in a novel class of pancreatic-cancer-initiating cells.
Author:	Jaiswal, Kshama R\|Xin, Hong-Wu\|Anderson, Andrew\|Wiegand, Gordon\|Kim, Bo\|Miller, Tyler\|Hari, Danielle\|Ray, Satyajit\|Koizumi, Tomotake\|Rudloff, Udo\|Thorgeirsson, Snorri S\|Avital, Itzhak
PMID:	22963768

59.
Journal:	J Biol Chem. 2012 Nov 9;287(46):39115-24.
Title:	CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor kappaB: implications for bidirectional tumor-stromal interactions.
Author:	Singh, Ajay P\|Arora, Sumit\|Bhardwaj, Arun\|Srivastava, Sanjeev K\|Kadakia, Madhavi P\|Wang, Bin\|Grizzle, William E\|Owen, Laurie B\|Singh, Seema
PMID:	22995914

60.
Journal:	Acta Radiol. 2012 Nov 1;53(9):1049-58.
Title:	Anti-CXCR4 monoclonal antibody conjugated to ultrasmall superparamagnetic iron oxide nanoparticles in an application of MR molecular imaging of pancreatic cancer cell lines.
Author:	He, Yonglan\|Song, Wei\|Lei, Jing\|Li, Zhuo\|Cao, Jian\|Huang, Shuai\|Meng, Jie\|Xu, Haiyan\|Jin, Zhengyu\|Xue, Huadan
PMID:	23012484

61.
Journal:	Exp Ther Med. 2012 Sep;4(3):363-369.
Title:	CXCL12/CXCR4 axis plays pivotal roles in the organ-specific metastasis of pancreatic adenocarcinoma: A clinical study.
Author:	Zhong, Weixia\|Chen, Weiwei\|Zhang, Dexian\|Sun, Jujie\|Li, Yuhui\|Zhang, Jianbo\|Gao, Yongsheng\|Zhou, Wuyuan\|Li, Sheng
PMID:	23181100

62.
Journal:	World J Surg Oncol. 2012 Dec 11;10:264.
Title:	MSH2 and CXCR4 involvement in malignant VIPoma.
Author:	Muller, Sven\|Kupka, Susan\|Konigsrainer, Ingmar\|Northoff, Hinnak\|Sotlar, Karl\|Bock, Thomas\|Kandolf, Reinhard\|Traub, Frank\|Konigsrainer, Alfred\|Zieker, Derek
PMID:	23231927

63.
Journal:	Oncogene. 2013 Aug 1;32(31):3638-47.
Title:	Pancreatic adenocarcinoma upregulated factor, a novel endothelial activator, promotes angiogenesis and vascular permeability.
Author:	Kim, S J\|Lee, Y\|Kim, N Y\|Hwang, Y\|Hwang, B\|Min, J-K\|Koh, S S
PMID:	22907431

64.
Journal:	Anticancer Agents Med Chem. 2013 Feb;13(2):261-9.
Title:	BRCA2 dysfunction promotes malignant transformation of pancreatic intraepithelial neoplasia.
Author:	Wang, Qi\|Liu, Hongrui\|Liu, Tingting\|Shu, Shizhen\|Jiang, He\|Cheng, Shidan\|Yuan, Yaozong\|Yang, Weiguo\|Wang, Lifu
PMID:	22934697

65.
Journal:	Int J Oncol. 2013 Mar;42(3):979-84.
Title:	Highly lymphatic metastatic pancreatic cancer cells possess stem cell-like properties.
Author:	Luo, Guopei\|Long, Jiang\|Cui, Xiaobo\|Xiao, Zhiwen\|Liu, Zuqiang\|Shi, Si\|Liu, Liang\|Liu, Chen\|Xu, Jin\|Li, Min\|Yu, Xianjun
PMID:	23338123

66.
Journal:	Int J Cancer. 2013 Jul 15;133(2):416-26.
Title:	Tspan8, CD44v6 and alpha6beta4 are biomarkers of migrating pancreatic cancer-initiating cells.
Author:	Wang, Haobin\|Rana, Sanyukta\|Giese, Nathalia\|Buchler, Markus W\|Zoller, Margot
PMID:	23338841

67.
Journal:	Acta Gastroenterol Belg. 2013 Mar;76(1):49-56.
Title:	Towards a tailored therapy in pancreatic cancer.
Author:	Marechal, Raphael\|Van Laethem, Jean-Luc
PMID:	23650783

68.
Journal:	J Cell Mol Med. 2013 Jun;17(6):792-9.
Title:	An intensified systemic trafficking of bone marrow-derived stem/progenitor cells in patients with pancreatic cancer.
Author:	Starzynska, Teresa\|Dabkowski, Krzysztof\|Blogowski, Wojciech\|Zuba-Surma, Ewa\|Budkowska, Marta\|Salata, Daria\|Dolegowska, Barbara\|Marlicz, Wojciech\|Lubikowski, Jerzy\|Ratajczak, Mariusz Z
PMID:	23672538

69.
Journal:	Mol Biol Rep. 2013 Jul;40(7):4139-46.
Title:	SDF-1alpha upregulation of MMP-2 is mediated by p38 MAPK signaling in pancreatic cancer cell lines.
Author:	Pan, Feng\|Ma, Shijie\|Cao, Weike\|Liu, Haining\|Chen, Fengli\|Chen, Xiaofei\|Shi, Ruihua
PMID:	23712777

70.
Journal:	J Biol Chem. 2013 Jul 19;288(29):21197-207.
Title:	An undesired effect of chemotherapy: gemcitabine promotes pancreatic cancer cell invasiveness through reactive oxygen species-dependent, nuclear factor kappaB- and hypoxia-inducible factor 1alpha-mediated up-regulation of CXCR4.
Author:	Arora, Sumit\|Bhardwaj, Arun\|Singh, Seema\|Srivastava, Sanjeev K\|McClellan, Steven\|Nirodi, Chaitanya S\|Piazza, Gary A\|Grizzle, William E\|Owen, Laurie B\|Singh, Ajay P
PMID:	23740244

71.
Journal:	J Biotechnol. 2013 Jul 20;166(4):166-73.
Title:	A bioengineered metastatic pancreatic tumor model for mechanistic investigation of chemotherapeutic drugs.
Author:	Wang, Xiaohui\|Zhang, Xing\|Fu, Zhiren\|Yin, Hao
PMID:	23747489

72.
Journal:	Front Biosci (Landmark Ed). 2013 Jun 1;18:795-802.
Title:	Cancer stem cell in the progression and therapy of pancreatic cancer.
Author:	Xu, Lantao
PMID:	23747847

73.
Journal:	Int J Nanomedicine. 2013;8:2465-72.
Title:	Drug-eluting scaffold to deliver chemotherapeutic medication for management of pancreatic cancer after surgery.
Author:	Zhan, Qian\|Shen, Baiyong\|Deng, Xiaxing\|Chen, Hao\|Jin, Jiabin\|Zhang, Xing\|Peng, Chenghong\|Li, Hongwei
PMID:	23885173

74.
Journal:	Anticancer Res. 2013 Sep;33(9):4103-10.
Title:	Aberrant expression of CXCR4 and beta-catenin in pancreatic cancer.
Author:	Wang, Zheng\|Ma, Qingyong\|Li, Pei\|Sha, Huanchen\|Li, Xuqi\|Xu, Jun
PMID:	24023356

75.
Journal:	Chin Med J (Engl). 2013;126(17):3371-4.
Title:	Role of CXCL12/CXCR4 signaling axis in pancreatic cancer.
Author:	Wu, Peng-Fei\|Lu, Zi-Peng\|Cai, Bao-Bao\|Tian, Lei\|Zou, Chen\|Jiang, Kui-Rong\|Miao, Yi
PMID:	24033967

76.
Journal:	Braz J Med Biol Res. 2013 Sep;46(9):758-64.
Title:	Adipose tissue-derived stem cells promote pancreatic cancer cell proliferation and invasion.
Author:	Ji, S Q\|Cao, J\|Zhang, Q Y\|Li, Y Y\|Yan, Y Q\|Yu, F X
PMID:	24068191

77.
Journal:	PLoS One. 2013 Sep 17;8(9):e73968.
Title:	Human pancreatic cancer contains a side population expressing cancer stem cell-associated and prognostic genes.
Author:	Van den Broeck, Anke\|Vankelecom, Hugo\|Van Delm, Wouter\|Gremeaux, Lies\|Wouters, Jasper\|Allemeersch, Joke\|Govaere, Olivier\|Roskams, Tania\|Topal, Baki
PMID:	24069258

78.
Journal:	Asian Pac J Cancer Prev. 2013;14(9):5403-8.
Title:	CXCL12-CXCR4 promotes proliferation and invasion of pancreatic cancer cells.
Author:	Shen, Bo\|Zheng, Ma-Qing\|Lu, Jian-Wei\|Jiang, Qian\|Wang, Tai-Hong\|Huang, Xin-En
PMID:	24175834

79.
Journal:	Zhonghua Wai Ke Za Zhi. 2013 Sep;51(9):834-8.
Title:	[Regulation effect of adipose-derived mesenchymal stem cells on pancreatic cancer cells].
Author:	Yu, Fu-Xiang\|Ji, Shi-Qiang\|Zhong, Jun-Qiao\|Zhu, Qian-Dong\|Li, Yang-Yang\|Zhang, Qi-Yu
PMID:	24330967

80.
Journal:	Mol Cancer Res. 2014 Mar;12(3):421-32.
Title:	Hypoxia-independent gene expression mediated by SOX9 promotes aggressive pancreatic tumor biology.
Author:	Camaj, Peter\|Jackel, Carsten\|Krebs, Stefan\|De Toni, Enrico N\|Blum, Helmut\|Jauch, Karl-Walter\|Nelson, Peter J\|Bruns, Christiane J
PMID:	24302456

81.
Journal:	PLoS One. 2014 Mar 4;9(3):e90400.
Title:	CXCL12 chemokine expression suppresses human pancreatic cancer growth and metastasis.
Author:	Roy, Ishan\|Zimmerman, Noah P\|Mackinnon, A Craig\|Tsai, Susan\|Evans, Douglas B\|Dwinell, Michael B
PMID:	24594697

82.
Journal:	Mol Biol Rep. 2014 Jul;41(7):4361-7.
Title:	Analysis of dysregulation of immune system in pancreatic cancer based on gene expression profile.
Author:	Wang, Baosheng\|Sun, Shaolong\|Liu, Zhen
PMID:	24619357

83.
Journal:	Mol Cancer Ther. 2014 Jul;13(7):1758-71.
Title:	Chloroquine targets pancreatic cancer stem cells via inhibition of CXCR4 and hedgehog signaling.
Author:	Balic, Anamaria\|Sorensen, Morten Draeby\|Trabulo, Sara Maria\|Sainz, Bruno Jr\|Cioffi, Michele\|Vieira, Catarina R\|Miranda-Lorenzo, Irene\|Hidalgo, Manuel\|Kleeff, Joerg\|Erkan, Mert\|Heeschen, Christopher
PMID:	24785258

84.
Journal:	Cancer Biol Ther. 2014 Aug;15(8):1087-93.
Title:	Ran GTPase protein promotes metastasis and invasion in pancreatic cancer by deregulating the expression of AR and CXCR4.
Author:	Deng, Lin\|Shang, Yulong\|Guo, Shikong\|Liu, Changhao\|Zhou, Lin\|Sun, Yi\|Nie, Yongzhan\|Fan, Daiming\|Lu, Yuanyuan\|Guo, Xuegang
PMID:	24840182

85.
Journal:	Asian Pac J Cancer Prev. 2014;15(12):4893-6.
Title:	Study on the relationship between CXCR4 expression and perineural invasion in pancreatic cancer.
Author:	Jiang, Yu-Mei\|Li, Guang\|Sun, Bao-Cun\|Zhao, Xiu-Lan\|Zhou, Zhong-Kai
PMID:	24998559

86.
Journal:	BMC Cancer. 2014 Sep 21;14:687.
Title:	Immunohistochemical analysis of cancer stem cell markers in pancreatic adenocarcinoma patients after neoadjuvant chemoradiotherapy.
Author:	Mizukami, Tatsuzo\|Kamachi, Hirofumi\|Mitsuhashi, Tomoko\|Tsuruga, Yosuke\|Hatanaka, Yutaka\|Kamiyama, Toshiya\|Matsuno, Yoshihiro\|Taketomi, Akinobu
PMID:	25240521

87.
Journal:	Anticancer Res. 2014 Dec;34(12):6897-911.
Title:	Nuclear receptors in pancreatic tumor cells.
Author:	Damaskos, Christos\|Garmpis, Nikolaos\|Karatzas, Theodore\|Kostakis, Ioannis D\|Nikolidakis, Lampros\|Kostakis, Alkiviadis\|Kouraklis, Gregory
PMID:	25503115

88.
Journal:	J Cancer Stem Cell Res. 2014;2.
Title:	A concise review on the current understanding of pancreatic cancer stem cells.
Author:	Vaz, Arokia Priyanka\|Ponnusamy, Moorthy P\|Seshacharyulu, Parthasarathy\|Batra, Surinder K
PMID:	26451384

89.
Journal:	Int J Clin Oncol. 2015 Jun;20(3):525-30.
Title:	CXCR4 promotes GSK3beta expression in pancreatic cancer cells via the Akt pathway.
Author:	Ma, Shijie\|Li, Qianjun\|Pan, Feng
PMID:	25145299

90.
Journal:	J Steroid Biochem Mol Biol. 2015 Apr;148:79-85.
Title:	Targeting cancer stem cells in solid tumors by vitamin D.
Author:	So, Jae Young\|Suh, Nanjoo
PMID:	25460302

91.
Journal:	Oncotarget. 2015 Jan 30;6(3):1490-506.
Title:	Overexpression of Nodal induces a metastatic phenotype in pancreatic cancer cells via the Smad2/3 pathway.
Author:	Duan, Wanxing\|Li, Rong\|Ma, Jiguang\|Lei, Jianjun\|Xu, Qinhong\|Jiang, Zhengdong\|Nan, Ligang\|Li, Xuqi\|Wang, Zheng\|Huo, Xiongwei\|Han, Liang\|Wu, Zheng\|Wu, Erxi\|Ma, Qingyong
PMID:	25557170

92.
Journal:	Oncotarget. 2015 Mar 10;6(7):4717-32.
Title:	Stromal-derived factor-1alpha/CXCL12-CXCR4 chemotactic pathway promotes perineural invasion in pancreatic cancer.
Author:	Xu, Qinhong\|Wang, Zheng\|Chen, Xin\|Duan, Wanxing\|Lei, Jianjun\|Zong, Liang\|Li, Xuqi\|Sheng, Liang\|Ma, Jiguang\|Han, Liang\|Li, Wei\|Zhang, Lun\|Guo, Kun\|Ma, Zhenhua\|Wu, Zheng\|Wu, Erxi\|Ma, Qingyong
PMID:	25605248

93.
Journal:	Oncotarget. 2015 Feb 20;6(5):3085-97.
Title:	Paracrine SDF-1alpha signaling mediates the effects of PSCs on GEM chemoresistance through an IL-6 autocrine loop in pancreatic cancer cells.
Author:	Zhang, Hui\|Wu, Huanwen\|Guan, Jian\|Wang, Li\|Ren, Xinyu\|Shi, Xiaohua\|Liang, Zhiyong\|Liu, Tonghua
PMID:	25609203

94.
Journal:	Oncotarget. 2015 Mar 10;6(7):5022-40.
Title:	CXCR4 over-expression and survival in cancer: a system review and meta-analysis.
Author:	Zhao, Hongli\|Guo, Liyuan\|Zhao, Hong\|Zhao, Jiaxin\|Weng, Hao\|Zhao, Bin
PMID:	25669980

95.
Journal:	Oncoscience. 2014 Nov 11;2(1):15-30.
Title:	Exosomal lipids induce human pancreatic tumoral MiaPaCa-2 cells resistance through the CXCR4-SDF-1alpha signaling axis.
Author:	Beloribi-Djefaflia, Sadia\|Siret, Carole\|Lombardo, Dominique
PMID:	25821841

96.
Journal:	Chem Res Toxicol. 2015 May 18;28(5):907-18.
Title:	Omeprazole Inhibits Pancreatic Cancer Cell Invasion through a Nongenomic Aryl Hydrocarbon Receptor Pathway.
Author:	Jin, Un-Ho\|Kim, Sang-Bae\|Safe, Stephen
PMID:	25826687

97.
Journal:	Pancreas. 2015 May;44(4):528-34.
Title:	The chemokine receptors CXCR4/CXCR7 and their primary heterodimeric ligands CXCL12 and CXCL12/high mobility group box 1 in pancreatic cancer growth and development: finding flow.
Author:	Shakir, Murtaza\|Tang, Daolin\|Zeh, Herbert J\|Tang, Siu Wah\|Anderson, Carolyn J\|Bahary, Nathan\|Lotze, Michael T
PMID:	25872129

98.
Journal:	Tumour Biol. 2015 Sep;36(10):7557-68.
Title:	Orthotopic inflammation-related pancreatic carcinogenesis in a wild-type mouse induced by combined application of caerulein and dimethylbenzanthracene.
Author:	Liang, Chen\|Wang, Zhen\|Wu, Li\|Wang, Chen\|Yu, Bao-Hua\|Yao, Xiu-Zhong\|Wang, Xiao-Lin\|Li, Ying-Yi
PMID:	25916208

99.
Journal:	Oncotarget. 2015 Nov 17;6(36):39140-50.
Title:	Gemcitabine triggers angiogenesis-promoting molecular signals in pancreatic cancer cells: Therapeutic implications.
Author:	Khan, Mohammad Aslam\|Srivastava, Sanjeev K\|Bhardwaj, Arun\|Singh, Seema\|Arora, Sumit\|Zubair, Haseeb\|Carter, James E\|Singh, Ajay P
PMID:	25970774

100.
Journal:	PLoS One. 2015 May 26;10(5):e0128059.
Title:	Chronic hyperglycemia induces trans-differentiation of human pancreatic stellate cells and enhances the malignant molecular communication with human pancreatic cancer cells.
Author:	Kiss, Katalin\|Baghy, Kornelia\|Spisak, Sandor\|Szanyi, Szilard\|Tulassay, Zsolt\|Zalatnai, Attila\|Lohr, J-Matthias\|Jesenofsky, Ralf\|Kovalszky, Ilona\|Firneisz, Gabor
PMID:	26010611

101.
Journal:	Tumour Biol. 2015 Nov;36(11):8637-43.
Title:	Application of chemokine receptor antagonist with stents reduces local inflammation and suppresses cancer growth.
Author:	Mao, Ai-Wu\|Jiang, Ting-Hui\|Sun, Xian-Jun\|Peng, Jian
PMID:	26044561

102.
Journal:	PLoS One. 2015 Jun 19;10(6):e0130192.
Title:	CXCR4--A Prognostic and Clinicopathological Biomarker for Pancreatic Ductal Adenocarcinoma: A Meta-Analysis.
Author:	Krieg, Andreas\|Riemer, Jasmin C\|Telan, Leila A\|Gabbert, Helmut E\|Knoefel, Wolfram T
PMID:	26091099

103.
Journal:	Cancer Cell Int. 2015 Jul 5;15:70.
Title:	GSK3beta mediates pancreatic cancer cell invasion in vitro via the CXCR4/MMP-2 Pathway.
Author:	Ying, Xu\|Jing, Li\|Ma, Shijie\|Li, Qianjun\|Luo, Xiaoling\|Pan, Zhenguo\|Feng, Yanling\|Feng, Pan
PMID:	26213494

104.
Journal:	Oncol Lett. 2015 Aug;10(2):835-840.
Title:	Hypoxia promotes C-X-C chemokine receptor type 4 expression through microRNA-150 in pancreatic cancer cells.
Author:	Sun, Jin-Shan\|Zhang, Xiao-Lan\|Yang, Yu-Jie\|Nie, Zhan-Guo\|Zhang, Yong
PMID:	26622579

105.
Journal:	J Nucl Med. 2016 May;57(5):741-6.
Title:	First Experience with Chemokine Receptor CXCR4-Targeted PET Imaging of Patients with Solid Cancers.
Author:	Vag, Tibor\|Gerngross, Carlos\|Herhaus, Peter\|Eiber, Matthias\|Philipp-Abbrederis, Kathrin\|Graner, Frank-Philipp\|Ettl, Johannes\|Keller, Ulrich\|Wester, Hans-Jurgen\|Schwaiger, Markus
PMID:	26769866

106.
Journal:	BMC Cancer. 2016 May 12;16:305.
Title:	Enhancement of the CXCL12/CXCR4 axis due to acquisition of gemcitabine resistance in pancreatic cancer: effect of CXCR4 antagonists.
Author:	Morimoto, Mamoru\|Matsuo, Yoichi\|Koide, Shuji\|Tsuboi, Ken\|Shamoto, Tomoya\|Sato, Takafumi\|Saito, Kenta\|Takahashi, Hiroki\|Takeyama, Hiromitsu
PMID:	27175473

107.
Journal:	Biomaterials. 2016 Sep;101:108-120.
Title:	Polyplex-mediated inhibition of chemokine receptor CXCR4 and chromatin-remodeling enzyme NCOA3 impedes pancreatic cancer progression and metastasis.
Author:	Wang, Yan\|Kumar, Sushil\|Rachagani, Satyanarayana\|Sajja, Balasrinivasa R\|Xie, Ying\|Hang, Yu\|Jain, Maneesh\|Li, Jing\|Boska, Michael D\|Batra, Surinder K\|Oupicky, David
PMID:	27267632

108.
Journal:	Pancreatology. 2016 Jul-Aug;16(4):632-9.
Title:	The utility of hyperthermic intra-abdominal chemotherapy with gemcitabine for the inhibition of tumor progression in an experimental model of pancreatic peritoneal carcinomatosis, in relation to their behavior with pancreatic cancer stem cells CD133+ CXCR
Author:	Garcia-Santos, Esther Pilar\|Padilla-Valverde, David\|Villarejo-Campos, Pedro\|Murillo-Lazaro, Cristina\|Fernandez-Grande, Esther\|Palomino-Munoz, Teodoro\|Rodriguez-Martinez, Marta\|Amo-Salas, Mariano\|Nunez-Guerrero, Paloma\|Sanchez-Garcia, Susana\|Puerto-Puerto,
PMID:	27289344

109.
Journal:	World J Gastroenterol. 2016 Jul 14;22(26):5971-6007.
Title:	Pancreatic cancer stem cell markers and exosomes - the incentive push.
Author:	Heiler, Sarah\|Wang, Zhe\|Zoller, Margot
PMID:	27468191

110.
Journal:	Oncol Rep. 2016 Nov;36(5):2875-2883.
Title:	Antitumor effects of herbal mixture extract in the pancreatic adenocarcinoma cell line PANC1.
Author:	Pak, Pyo June\|Kang, Beob Hwa\|Park, Sung Hyo\|Sung, Ji Hyun\|Joo, Yong Hoon\|Jung, Seung Hyun\|Chung, Namhyun
PMID:	27599899

111.
Journal:	Carcinogenesis. 2016 Nov 1;37(11):1052-1061.
Title:	Honokiol suppresses pancreatic tumor growth, metastasis and desmoplasia by interfering with tumor-stromal cross-talk.
Author:	Averett, Courey\|Bhardwaj, Arun\|Arora, Sumit\|Srivastava, Sanjeev K\|Khan, Mohammad Aslam\|Ahmad, Aamir\|Singh, Seema\|Carter, James E\|Khushman, Moh'd\|Singh, Ajay P
PMID:	27609457

112.
Journal:	Am J Cancer Res. 2016 Oct 1;6(10):2192-2206. eCollection 2016.
Title:	Radiation promotes epithelial-to-mesenchymal transition and invasion of pancreatic cancer cell by activating carcinoma-associated fibroblasts.
Author:	Li, Doudou\|Qu, Chao\|Ning, Zhouyu\|Wang, Haiyong\|Zang, Kun\|Zhuang, Liping\|Chen, Lianyu\|Wang, Peng\|Meng, Zhiqiang
PMID:	27822411

113.
Journal:	Sci Transl Med. 2016 Nov 9;8(364):364ra153.
Title:	Local and transient gene expression primes the liver to resist cancer metastasis.
Author:	Goodwin, Tyler J\|Zhou, Yingqiu\|Musetti, Sara N\|Liu, Rihe\|Huang, Leaf
PMID:	27831902

114.
Journal:	Oncotarget. 2017 Jan 24;8(4):5717-5734.
Title:	Hormophysa triquerta polyphenol, an elixir that deters CXCR4- and COX2-dependent dissemination destiny of treatment-resistant pancreatic cancer cells.
Author:	Aravindan, Sheeja\|Ramraj, Satishkumar\|Kandasamy, Kathiresan\|Thirugnanasambandan, Somasundaram S\|Somasundaram, Dinesh Babu\|Herman, Terence S\|Aravindan, Natarajan
PMID:	27974694

115.
Journal:	Proc Natl Acad Sci U S A. 2017 Jan 3;114(1):E85-E94.
Title:	Early pancreatic cancer lesions suppress pain through CXCL12-mediated chemoattraction of Schwann cells.
Author:	Demir, Ihsan Ekin\|Kujundzic, Kristina\|Pfitzinger, Paulo L\|Saricaoglu, Omer Cemil\|Teller, Steffen\|Kehl, Timo\|Reyes, Carmen Mota\|Ertl, Linda S\|Miao, Zhenhua\|Schall, Thomas J\|Tieftrunk, Elke\|Haller, Bernhard\|Diakopoulos, Kalliope Nina\|Kurkowski, Magdalena U\|
PMID:	27986950

116.
Journal:	Cancer Lett. 2017 Jul 1;397:43-51.
Title:	Galectin-1-driven upregulation of SDF-1 in pancreatic stellate cells promotes pancreatic cancer metastasis.
Author:	Qian, Dong\|Lu, Zipeng\|Xu, Qingcheng\|Wu, Pengfei\|Tian, Lei\|Zhao, Liangtao\|Cai, Baobao\|Yin, Jie\|Wu, Yang\|Staveley-O'Carroll, Kevin F\|Jiang, Kuirong\|Miao, Yi\|Li, Guangfu
PMID:	28336327

117.
Journal:	BMC Cancer. 2017 Mar 29;17(1):229.
Title:	Protocol of the PANCALYZE trial: a multicenter, prospective study investigating the tumor biomarkers CXCR4, SMAD4, SOX9 and IFIT3 in patients with resected pancreatic adenocarcinoma to predict the pattern of recurrence of the disease.
Author:	Popp, Felix C\|Popp, Marie Christine\|Zhao, Yue\|Betzler, Christopher\|Kropf, Siegfried\|Garlipp, Benjamin\|Benckert, Christoph\|Kalinski, Thomas\|Lippert, Hans\|Bruns, Christiane J
PMID:	28356064

118.
Journal:	Gene. 2017 Aug 20;625:72-77.
Title:	Integrated clinicopathological features and gene microarray analysis of pancreatic neuroendocrine tumors.
Author:	Zhou, Huaqiang\|Chen, Qinchang\|Tan, Wulin\|Qiu, Zeting\|Li, Si\|Song, Yiyan\|Gao, Shaowei
PMID:	28479381

119.
Journal:	Pharmacol Ther. 2017 Nov;179:158-170.
Title:	Emerging roles of the CXCL12/CXCR4 axis in pancreatic cancer progression and therapy.
Author:	Sleightholm, Richard L\|Neilsen, Beth K\|Li, Jing\|Steele, Maria M\|Singh, Rakesh K\|Hollingsworth, Michael A\|Oupicky, David
PMID:	28549596

120.
Journal:	Oncogene. 2017 Sep 28;36(39):5532-5543.
Title:	KLF10 loss in the pancreas provokes activation of SDF-1 and induces distant metastases of pancreatic ductal adenocarcinoma in the Kras(G12D) p53(flox/flox) model.
Author:	Weng, C-C\|Hawse, J R\|Subramaniam, M\|Chang, V H S\|Yu, W C Y\|Hung, W-C\|Chen, L-T\|Cheng, K-H
PMID:	28581520

121.
Journal:	J Surg Oncol. 2017 Jul;116(1):7-15.
Title:	The pancreatic cancer microenvironment: A true double agent.
Author:	Melstrom, Laleh G\|Salazar, Marcela D\|Diamond, Don J
PMID:	28605029

122.
Journal:	Oncotarget. 2016 Dec 24;8(32):52381-52402.
Title:	Galeterone and its analogs inhibit Mnk-eIF4E axis, synergize with gemcitabine, impede pancreatic cancer cell migration, invasion and proliferation and inhibit tumor growth in mice.
Author:	Kwegyir-Afful, Andrew K\|Murigi, Francis N\|Purushottamachar, Puranik\|Ramamurthy, Vidya P\|Martin, Marlena S\|Njar, Vincent C O
PMID:	28881737

123.
Journal:	Cell Physiol Biochem. 2017;43(2):840-851.
Title:	CXCR4/Let-7a Axis Regulates Metastasis and Chemoresistance of Pancreatic Cancer Cells Through Targeting HMGA2.
Author:	Xiao, Guangfa\|Wang, Xitao\|Yu, Yaqun
PMID:	28954272

124.
Journal:	Oncol Lett. 2017 Dec;14(6):6395-6402.
Title:	Identification of molecular mechanisms of glutamine in pancreatic cancer.
Author:	Jia, Zhen-Yi\|Shen, Tong-Yi\|Jiang, Wei\|Qin, Huan-Long
PMID:	29163679

125.
Journal:	Mol Cancer Res. 2018 Jan;16(1):162-172.
Title:	NFkappaB-Mediated Invasiveness in CD133(+) Pancreatic TICs Is Regulated by Autocrine and Paracrine Activation of IL1 Signaling.
Author:	Nomura, Alice\|Gupta, Vineet K\|Dauer, Patricia\|Sharma, Nikita S\|Dudeja, Vikas\|Merchant, Nipun\|Saluja, Ashok K\|Banerjee, Sulagna
PMID:	28970361

126.
Journal:	Cancer Res. 2018 Jan 15;78(2):558-571.
Title:	Photodynamic Priming Mitigates Chemotherapeutic Selection Pressures and Improves Drug Delivery.
Author:	Huang, Huang-Chiao\|Rizvi, Imran\|Liu, Joyce\|Anbil, Sriram\|Kalra, Ashish\|Lee, Helen\|Baglo, Yan\|Paz, Nancy\|Hayden, Douglas\|Pereira, Steve\|Pogue, Brian W\|Fitzgerald, Jonathan\|Hasan, Tayyaba
PMID:	29187403

127.
Journal:	Oncol Lett. 2018 Feb;15(2):1771-1776.
Title:	Mechanisms by which CXCR4/CXCL12 cause metastatic behavior in pancreatic cancer.
Author:	Zhang, Jianbo\|Liu, Chengxin\|Mo, Xinkai\|Shi, Huan\|Li, Sheng
PMID:	29434873

128.
Journal:	Exp Cell Res. 2018 Apr 1;365(1):12-23.
Title:	Artemin regulates CXCR4 expression to induce migration and invasion in pancreatic cancer cells through activation of NF-kappaB signaling.
Author:	Wang, Juan\|Wang, Hui\|Cai, Jun\|Du, Shaoxia\|Xin, Beibei\|Wei, Wei\|Zhang, Ti\|Shen, Xiaohong
PMID:	29453972

129.
Journal:	Cancer Lett. 2018 Jul 10;426:14-24.
Title:	Simvastatin inhibits sonic hedgehog signaling and stemness features of pancreatic cancer.
Author:	Yin, Yefeng\|Liu, Li\|Zhao, Zhefu\|Yin, Libo\|Bauer, Nathalie\|Nwaeburu, Clifford C\|Gladkich, Jury\|Gross, Wolfgang\|Hackert, Thilo\|Sticht, Carsten\|Gretz, Norbert\|Strobel, Oliver\|Herr, Ingrid
PMID:	29627496

130.
Journal:	Cell Death Dis. 2018 Oct 18;9(11):1065.
Title:	Cancer-associated fibroblasts promote progression and gemcitabine resistance via the SDF-1/SATB-1 pathway in pancreatic cancer.
Author:	Wei, Lusheng\|Ye, Huilin\|Li, Guolin\|Lu, Yuanting\|Zhou, Quanbo\|Zheng, Shangyou\|Lin, Qing\|Liu, Yimin\|Li, Zhihua\|Chen, Rufu
PMID:	30337520