Primary Site >> Colorectal Cancer
Gene >> CXCR4
| 1. | |||||||||||
| Journal: | Exp Nephrol. 2002;10(2):114-9. | ||||||||||
| Title: | Gene expression profiling in silico: relative expression of candidate angiogenesis associated genes in renal cell carcinomas. | ||||||||||
| Author: | Gerritsen, Mary E|Peale, Franklin V Jr|Wu, Thomas | ||||||||||
| PMID: | 11937758 | ||||||||||
| 2. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9410-4. | ||||||||||
| Title: | Transepithelial transport of HIV-1 by M cells is receptor-mediated. | ||||||||||
| Author: | Fotopoulos, Grigorios|Harari, Alexandre|Michetti, Pierre|Trono, Didier|Pantaleo, Giuseppe|Kraehenbuhl, Jean-Pierre | ||||||||||
| PMID: | 12093918 | ||||||||||
| 3. | |||||||||||
| Journal: | Virology. 2002 Dec 20;304(2):403-14. | ||||||||||
| Title: | Adaptation of a CXCR4-using human immunodeficiency type 1 NDK virus in intestinal cells is associated with CD4-independent replication. | ||||||||||
| Author: | Chenine, Agnes-Laurence|Pion, Marjorie|Matouskova, Eva|Gondois-Rey, Francoise|Vigne, Robert|Hirsch, Ivan | ||||||||||
| PMID: | 12504579 | ||||||||||
| 4. | |||||||||||
| Journal: | Cancer Res. 2003 Jul 1;63(13):3833-9. | ||||||||||
| Title: | The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases. | ||||||||||
| Author: | Zeelenberg, Ingrid S|Ruuls-Van Stalle, Lisette|Roos, Ed | ||||||||||
| PMID: | 12839981 | ||||||||||
| 5. | |||||||||||
| Journal: | Cancer Immunol Immunother. 2005 Aug;54(8):781-91. Epub 2004 Dec 11. | ||||||||||
| Title: | Inhibitory effects of anti-CXCR4 antibodies on human colon cancer cells. | ||||||||||
| Author: | Ottaiano, Alessandro|di Palma, Antonella|Napolitano, Maria|Pisano, Carmen|Pignata, Sandro|Tatangelo, Fabiana|Botti, Gerardo|Acquaviva, Angela Maria|Castello, Giuseppe|Ascierto, Paolo Antonio|Iaffaioli, Rosario Vincenzo|Scala, Stefania | ||||||||||
| PMID: | 15592929 | ||||||||||
| 6. | |||||||||||
| Journal: | Clin Cancer Res. 2005 Mar 1;11(5):1743-50. | ||||||||||
| Title: | Effect of chemokine receptors CXCR4 and CCR7 on the metastatic behavior of human colorectal cancer. | ||||||||||
| Author: | Schimanski, Carl C|Schwald, Stefan|Simiantonaki, Nektaria|Jayasinghe, Caren|Gonner, Ursula|Wilsberg, Vanessa|Junginger, Theodor|Berger, Martin R|Galle, Peter R|Moehler, Markus | ||||||||||
| PMID: | 15755995 | ||||||||||
| 7. | |||||||||||
| Journal: | Int J Cancer. 2005 Sep 20;116(5):726-33. | ||||||||||
| Title: | Prediction of lymph node metastasis in colorectal carcinoma by expressionof chemokine receptor CCR7. | ||||||||||
| Author: | Gunther, Klaus|Leier, Julia|Henning, Golo|Dimmler, Arno|Weissbach, Rafael|Hohenberger, Werner|Forster, Reinhold | ||||||||||
| PMID: | 15828050 | ||||||||||
| 8. | |||||||||||
| Journal: | J Clin Oncol. 2005 Apr 20;23(12):2744-53. | ||||||||||
| Title: | Chemokine receptor CXCR4 expression in colorectal cancer patients increases the risk for recurrence and for poor survival. | ||||||||||
| Author: | Kim, Joseph|Takeuchi, Hiroya|Lam, Stella T|Turner, Roderick R|Wang, He-Jing|Kuo, Christine|Foshag, Leland|Bilchik, Anton J|Hoon, Dave S B | ||||||||||
| PMID: | 15837989 | ||||||||||
| 9. | |||||||||||
| Journal: | Oncology. 2005;68(2-3):276-84. Epub 2005 Jul 7. | ||||||||||
| Title: | Dendritic cells and vascular endothelial growth factor in colorectal cancer: correlations with clinicobiological findings. | ||||||||||
| Author: | Della Porta, Matteo|Danova, Marco|Rigolin, Gian Matteo|Brugnatelli, Silvia|Rovati, Bianca|Tronconi, Chiara|Fraulini, Chiara|Russo Rossi, Antonella|Riccardi, Alberto|Castoldi, Gianluigi | ||||||||||
| PMID: | 16015045 | ||||||||||
| 10. | |||||||||||
| Journal: | Exp Cell Res. 2005 Oct 15;310(1):117-30. | ||||||||||
| Title: | CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation. | ||||||||||
| Author: | Brand, Stephan|Dambacher, Julia|Beigel, Florian|Olszak, Torsten|Diebold, Joachim|Otte, Jan-Michel|Goke, Burkhard|Eichhorst, Soren T | ||||||||||
| PMID: | 16125170 | ||||||||||
| 11. | |||||||||||
| Journal: | Oncogene. 2006 Aug 17;25(36):4986-97. Epub 2006 Mar 27. | ||||||||||
| Title: | Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis. | ||||||||||
| Author: | Wendt, M K|Johanesen, P A|Kang-Decker, N|Binion, D G|Shah, V|Dwinell, M B | ||||||||||
| PMID: | 16568088 | ||||||||||
| 12. | |||||||||||
| Journal: | Tumour Biol. 2006;27(3):166-74. | ||||||||||
| Title: | Involvement of chemokine receptor CCR6 in colorectal cancer metastasis. | ||||||||||
| Author: | Rubie, Claudia|Oliveira, Vilma|Kempf, Katja|Wagner, Mathias|Tilton, Bettina|Rau, Bettina|Kruse, Bianca|Konig, Jochen|Schilling, Martin | ||||||||||
| PMID: | 16641550 | ||||||||||
| 13. | |||||||||||
| Journal: | Clin Cancer Res. 2006 May 1;12(9):2795-803. | ||||||||||
| Title: | Overexpression of both CXC chemokine receptor 4 and vascular endothelial growth factor proteins predicts early distant relapse in stage II-III colorectal cancer patients. | ||||||||||
| Author: | Ottaiano, Alessandro|Franco, Renato|Aiello Talamanca, Annarita|Liguori, Giuseppina|Tatangelo, Fabiana|Delrio, Paolo|Nasti, Guglielmo|Barletta, Emiddio|Facchini, Gaetano|Daniele, Bruno|Di Blasi, Arturo|Napolitano, Maria|Ierano, Caterina|Calemma, Rosa|Leona | ||||||||||
| PMID: | 16675573 | ||||||||||
| 14. | |||||||||||
| Journal: | Transplantation. 2006 Jun 15;81(11):1558-67. | ||||||||||
| Title: | In vivo luminescent imaging of cyclosporin A-mediated cancer progression in rats. | ||||||||||
| Author: | Ohsawa, Ichiro|Murakami, Takashi|Uemoto, Shinji|Kobayashi, Eiji | ||||||||||
| PMID: | 16770245 | ||||||||||
| 15. | |||||||||||
| Journal: | Ann Surg. 2006 Jul;244(1):113-20. | ||||||||||
| Title: | Chemokine receptor CXCR4 expression in patients with melanoma and colorectal cancer liver metastases and the association with disease outcome. | ||||||||||
| Author: | Kim, Joseph|Mori, Takuji|Chen, Steven L|Amersi, Farin F|Martinez, Steve R|Kuo, Christine|Turner, Roderick R|Ye, Xing|Bilchik, Anton J|Morton, Donald L|Hoon, Dave S B | ||||||||||
| PMID: | 16794396 | ||||||||||
| 16. | |||||||||||
| Journal: | Int J Cancer. 2006 Nov 1;119(9):2044-53. | ||||||||||
| Title: | Adenosine upregulates CXCR4 and enhances the proliferative and migratory responses of human carcinoma cells to CXCL12/SDF-1alpha. | ||||||||||
| Author: | Richard, Cynthia Lee|Tan, Ernest Yoh|Blay, Jonathan | ||||||||||
| PMID: | 16823836 | ||||||||||
| 17. | |||||||||||
| Journal: | World J Gastroenterol. 2006 Nov 7;12(41):6627-33. | ||||||||||
| Title: | Chemokine expression in hepatocellular carcinoma versus colorectal liver metastases. | ||||||||||
| Author: | Rubie, Claudia|Frick, Vilma Oliveira|Wagner, Mathias|Weber, Christina|Kruse, Bianca|Kempf, Katja|Konig, Jochen|Rau, Bettina|Schilling, Martin | ||||||||||
| PMID: | 17075975 | ||||||||||
| 18. | |||||||||||
| Journal: | Oncology. 2006;71(3-4):204-11. Epub 2007 Jul 19. | ||||||||||
| Title: | Association between expression of vascular endothelial growth factor C, chemokine receptor CXCR4 and lymph node metastasis in colorectal cancer. | ||||||||||
| Author: | Fukunaga, S|Maeda, K|Noda, E|Inoue, T|Wada, K|Hirakawa, K | ||||||||||
| PMID: | 17641542 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncogene. 2007 May 17;26(23):3329-37. Epub 2006 Nov 27. | ||||||||||
| Title: | Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion. | ||||||||||
| Author: | Mehta, S A|Christopherson, K W|Bhat-Nakshatri, P|Goulet, R J Jr|Broxmeyer, H E|Kopelovich, L|Nakshatri, H | ||||||||||
| PMID: | 17130833 | ||||||||||
| 20. | |||||||||||
| Journal: | Int J Mol Med. 2007 Jan;19(1):11-5. | ||||||||||
| Title: | Polymorphism and circulating levels of the chemokine CXCL12 in colorectal cancer patients. | ||||||||||
| Author: | Dimberg, Jan|Hugander, Anders|Lofgren, Sture|Wagsater, Dick | ||||||||||
| PMID: | 17143542 | ||||||||||
| 21. | |||||||||||
| Journal: | Oncogene. 2007 Jul 12;26(32):4679-88. Epub 2007 Feb 5. | ||||||||||
| Title: | Chemokine receptor CXCR3 promotes colon cancer metastasis to lymph nodes. | ||||||||||
| Author: | Kawada, K|Hosogi, H|Sonoshita, M|Sakashita, H|Manabe, T|Shimahara, Y|Sakai, Y|Takabayashi, A|Oshima, M|Taketo, M M | ||||||||||
| PMID: | 17297455 | ||||||||||
| 22. | |||||||||||
| Journal: | Int J Oncol. 2007 May;30(5):1215-22. | ||||||||||
| Title: | Thiazolidinedione drugs down-regulate CXCR4 expression on human colorectal cancer cells in a peroxisome proliferator activated receptor gamma-dependent manner. | ||||||||||
| Author: | Richard, Cynthia Lee|Blay, Jonathan | ||||||||||
| PMID: | 17390024 | ||||||||||
| 23. | |||||||||||
| Journal: | Exp Cell Res. 2007 Oct 1;313(16):3446-58. Epub 2007 Jul 13. | ||||||||||
| Title: | 15-Deoxy-delta(12,14)-prostaglandin J(2) down-regulates CXCR4 on carcinoma cells through PPARgamma- and NFkappaB-mediated pathways. | ||||||||||
| Author: | Richard, Cynthia Lee|Lowthers, Erica Lauren|Blay, Jonathan | ||||||||||
| PMID: | 17707368 | ||||||||||
| 24. | |||||||||||
| Journal: | Cancer Sci. 2007 Nov;98(11):1652-8. | ||||||||||
| Title: | Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response. | ||||||||||
| Author: | Koizumi, Keiichi|Hojo, Shozo|Akashi, Takuya|Yasumoto, Kazuo|Saiki, Ikuo | ||||||||||
| PMID: | 17894551 | ||||||||||
| 25. | |||||||||||
| Journal: | World J Gastroenterol. 2008 Apr 21;14(15):2308-13. | ||||||||||
| Title: | Inhibition of CXCR4 activity with AMD3100 decreases invasion of human colorectal cancer cells in vitro. | ||||||||||
| Author: | Li, Ji-Kun|Yu, Liang|Shen, Yun|Zhou, Li-Sheng|Wang, Yi-Cheng|Zhang, Jian-Hai | ||||||||||
| PMID: | 18416455 | ||||||||||
| 26. | |||||||||||
| Journal: | Br J Cancer. 2008 May 20;98(10):1682-9. | ||||||||||
| Title: | Expression of SDF-1 alpha and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer. | ||||||||||
| Author: | Yoshitake, N|Fukui, H|Yamagishi, H|Sekikawa, A|Fujii, S|Tomita, S|Ichikawa, K|Imura, J|Hiraishi, H|Fujimori, T | ||||||||||
| PMID: | 18443596 | ||||||||||
| 27. | |||||||||||
| Journal: | Gastroenterology. 2008 Aug;135(2):508-17. | ||||||||||
| Title: | Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells. | ||||||||||
| Author: | Wendt, Michael K|Drury, Luke J|Vongsa, Rebecca A|Dwinell, Michael B | ||||||||||
| PMID: | 18558091 | ||||||||||
| 28. | |||||||||||
| Journal: | Zhonghua Wei Chang Wai Ke Za Zhi. 2008 Sep;11(5):482-6. | ||||||||||
| Title: | [Expression of chemokine receptor CXCR4 in colorectal carcinoma and its relationship with clinicopathological parameters]. | ||||||||||
| Author: | Yu, Liang|Shen, Yun|Li, Ji-Kun|Sun, Yu-Hao|Wang, Yi-Cheng|Zhang, Jian-Hai | ||||||||||
| PMID: | 18803056 | ||||||||||
| 29. | |||||||||||
| Journal: | Scand J Immunol. 2008 Dec;68(6):635-44. | ||||||||||
| Title: | Differential CXC receptor expression in colorectal carcinomas. | ||||||||||
| Author: | Rubie, C|Kollmar, O|Frick, V O|Wagner, M|Brittner, B|Graber, S|Schilling, M K | ||||||||||
| PMID: | 18959627 | ||||||||||
| 30. | |||||||||||
| Journal: | Cancer Immunol Immunother. 2009 Jan;58(1):85-94. | ||||||||||
| Title: | Expression and function of T cell homing molecules in Hodgkin's lymphoma. | ||||||||||
| Author: | Machado, Lee|Jarrett, Ruth|Morgan, Susan|Murray, Paul|Hunter, Beatrix|Hamilton, Emma|Crocker, John|Thomas, Wendy|Steven, Neil|Ismail, Tariq|Chapman, Ann|Adams, David H|Lee, Steven P | ||||||||||
| PMID: | 18488221 | ||||||||||
| 31. | |||||||||||
| Journal: | J Oral Pathol Med. 2009 Feb;38(2):214-9. | ||||||||||
| Title: | CXCR-4 knockdown by small interfering RNA inhibits cell proliferation and invasion of oral squamous cell carcinoma cells. | ||||||||||
| Author: | Hong, Ji-Soo|Pai, Hyun-Kyung|Hong, Kyoung-Ok|Kim, Mi-Ae|Kim, Ji-Hong|Lee, Jae-Il|Hong, Sam-Pyo|Hong, Seong-Doo | ||||||||||
| PMID: | 18624931 | ||||||||||
| 32. | |||||||||||
| Journal: | Cell Cycle. 2009 Apr 15;8(8):1228-37. Epub 2009 Apr 23. | ||||||||||
| Title: | A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration. | ||||||||||
| Author: | Ierano, Caterina|Giuliano, Paola|D'Alterio, Crescenzo|Cioffi, Michele|Mettivier, Valentina|Portella, Luigi|Napolitano, Maria|Barbieri, Antonio|Arra, Claudio|Liguori, Giuseppina|Franco, Renato|Palmieri, Giuseppe|Rozzo, Carla|Pacelli, Roberto|Castello, Gius | ||||||||||
| PMID: | 19305148 | ||||||||||
| 33. | |||||||||||
| Journal: | Cancer Microenviron. 2009 Dec;2(1):1-7. | ||||||||||
| Title: | Nuclear localization of CXCR4 determines prognosis for colorectal cancer patients. | ||||||||||
| Author: | Speetjens, Frank M|Liefers, Gerrit Jan|Korbee, Cornelis J|Mesker, Wilma E|van de Velde, Cornelis J H|van Vlierberghe, Ronald L|Morreau, Hans|Tollenaar, Rob A|Kuppen, Peter J K | ||||||||||
| PMID: | 19308676 | ||||||||||
| 34. | |||||||||||
| Journal: | Clin Colorectal Cancer. 2009 Mar;8(2):100-5. | ||||||||||
| Title: | Brain metastases from colorectal cancer: risk factors, incidence, and the possible role of chemokines. | ||||||||||
| Author: | Mongan, John P|Fadul, Camilo E|Cole, Bernard F|Zaki, Bassem I|Suriawinata, Arief A|Ripple, Gregory H|Tosteson, Tor D|Pipas, J Marc | ||||||||||
| PMID: | 19423503 | ||||||||||
| 35. | |||||||||||
| Journal: | Ann Surg Oncol. 2009 Aug;16(8):2323-30. | ||||||||||
| Title: | SDF-1alpha G801A polymorphism predicts lymph node metastasis in stage T3 colorectal cancer. | ||||||||||
| Author: | Chang, Shih-Ching|Lin, Pei-Ching|Yang, Shung-Haur|Wang, Huann-Sheng|Li, Anna Fen-Yau|Lin, Jen-Kou | ||||||||||
| PMID: | 19472013 | ||||||||||
| 36. | |||||||||||
| Journal: | Zhonghua Wai Ke Za Zhi. 2009 Feb 1;47(3):210-3. | ||||||||||
| Title: | [Effect of stromal cell-derived factor-1 and its receptor CXCR4 on liver metastasis of human colon cancer]. | ||||||||||
| Author: | Ding, Yin-Lu|Fu, Qin-Ye|Tang, Si-Feng|Zhang, Jian-Liang|Li, Zhan-Yuan|Li, Zhao-Ting | ||||||||||
| PMID: | 19563077 | ||||||||||
| 37. | |||||||||||
| Journal: | Neoplasia. 2009 Jul;11(7):651-61. | ||||||||||
| Title: | CXCR4 regulates the early extravasation of metastatic tumor cells in vivo. | ||||||||||
| Author: | Gassmann, Peter|Haier, Jorg|Schluter, Kerstin|Domikowsky, Britta|Wendel, Claudia|Wiesner, Ulrike|Kubitza, Robert|Engers, Rainer|Schneider, Stephan W|Homey, Bernhard|Muller, Anja | ||||||||||
| PMID: | 19568410 | ||||||||||
| 38. | |||||||||||
| Journal: | Ann Surg Oncol. 2009 Sep;16(9):2645-53. | ||||||||||
| Title: | Hepatic stellate cells promote liver metastasis of colon cancer cells by the action of SDF-1/CXCR4 axis. | ||||||||||
| Author: | Matsusue, Ryo|Kubo, Hajime|Hisamori, Shigeo|Okoshi, Kae|Takagi, Hidekazu|Hida, Koya|Nakano, Keiko|Itami, Atsushi|Kawada, Kenji|Nagayama, Satoshi|Sakai, Yoshiharu | ||||||||||
| PMID: | 19588204 | ||||||||||
| 39. | |||||||||||
| Journal: | Zhonghua Zhong Liu Za Zhi. 2009 Apr;31(4):260-4. | ||||||||||
| Title: | [Association of CXCR4 and SDF-1alpha with organ-specific metastasis of nasopharyngeal carcinoma]. | ||||||||||
| Author: | Luo, Hua-nan|Li, Xiang-ping|Liu, Xiong|Zhang, Guo-hua|Liu, You-li | ||||||||||
| PMID: | 19615279 | ||||||||||
| 40. | |||||||||||
| Journal: | Int J Cancer. 2009 Nov 1;125(9):2187-97. | ||||||||||
| Title: | Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model. | ||||||||||
| Author: | Kunnumakkara, Ajaikumar B|Diagaradjane, Parmeswaran|Anand, Preetha|Harikumar, Kuzhuvelil B|Deorukhkar, Amit|Gelovani, Juri|Guha, Sushovan|Krishnan, Sunil|Aggarwal, Bharat B | ||||||||||
| PMID: | 19623659 | ||||||||||
| 41. | |||||||||||
| Journal: | Cancer Biol Ther. 2009 Sep;8(17):1608-14. Epub 2009 Sep 6. | ||||||||||
| Title: | CXCL12, CXCR4 and CXCR7 expression in brain metastases. | ||||||||||
| Author: | Salmaggi, Andrea|Maderna, Emanuela|Calatozzolo, Chiara|Gaviani, Paola|Canazza, Alessandra|Milanesi, Ida|Silvani, Antonio|DiMeco, Francesco|Carbone, Antonino|Pollo, Bianca | ||||||||||
| PMID: | 19625779 | ||||||||||
| 42. | |||||||||||
| Journal: | Clin Colorectal Cancer. 2009 Apr;8(2):100-5. | ||||||||||
| Title: | Brain metastases from colorectal cancer: risk factors, incidence, and the possible role of chemokines. | ||||||||||
| Author: | Mongan, John P|Fadul, Camilo E|Cole, Bernard F|Zaki, Bassem I|Suriawinata, Arief A|Ripple, Gregory H|Tosteson, Tor D|Pipas, J Marc | ||||||||||
| PMID: | 19739271 | ||||||||||
| 43. | |||||||||||
| Journal: | Cancer Res. 2009 Oct 15;69(20):7905-10. | ||||||||||
| Title: | Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer. | ||||||||||
| Author: | Xu, Lei|Duda, Dan G|di Tomaso, Emmanuelle|Ancukiewicz, Marek|Chung, Daniel C|Lauwers, Gregory Y|Samuel, Rekha|Shellito, Paul|Czito, Brian G|Lin, Pei-Chun|Poleski, Martin|Bentley, Rex|Clark, Jeffrey W|Willett, Christopher G|Jain, Rakesh K | ||||||||||
| PMID: | 19826039 | ||||||||||
| 44. | |||||||||||
| Journal: | Histopathology. 2009 Nov;55(5):576-86. | ||||||||||
| Title: | The role of vascular CXCR4 expression in colorectal carcinoma. | ||||||||||
| Author: | Ingold, Barbara|Schulz, Stefan|Budczies, Jan|Neumann, Ulf|Ebert, Matthias P A|Weichert, Wilko|Rocken, Christoph | ||||||||||
| PMID: | 19912363 | ||||||||||
| 45. | |||||||||||
| Journal: | Zhonghua Wei Chang Wai Ke Za Zhi. 2009 Nov;12(6):627-9. | ||||||||||
| Title: | [Shikonin down-regulates CXCR4 expression and inhibits CXCL12-induced migratory responses in colorectal carcinoma cell line SW480]. | ||||||||||
| Author: | Wen, Zhuo-fu|Wei, Xiu-qing|Guo, Yun-wei|Zheng, Feng-ping | ||||||||||
| PMID: | 19921580 | ||||||||||
| 46. | |||||||||||
| Journal: | Mol Cell Pharmacol. 2009 Aug 5;1(2):85-91. | ||||||||||
| Title: | HIV Nef-M1 Effects on Colorectal Cancer Growth in Tumor-induced Spleens and Hepatic Metastasis. | ||||||||||
| Author: | Harrington, Willie|Bond, Vincent|Huang, Ming Bo|Powell, Michael|Lillard, James|Manne, Upender|Bumpers, Harvey | ||||||||||
| PMID: | 20383296 | ||||||||||
| 47. | |||||||||||
| Journal: | Mol Carcinog. 2010 Jan;49(1):94-103. | ||||||||||
| Title: | Aberrant DNA methylation occurs in colon neoplasms arising in the azoxymethane colon cancer model. | ||||||||||
| Author: | Borinstein, Scott C|Conerly, Melissa|Dzieciatkowski, Slavomir|Biswas, Swati|Washington, M Kay|Trobridge, Patty|Henikoff, Steve|Grady, William M | ||||||||||
| PMID: | 19777566 | ||||||||||
| 48. | |||||||||||
| Journal: | Int J Cancer. 2010 Mar 15;126(6):1302-15. | ||||||||||
| Title: | CXCR4 and CXCR7 regulate angiogenesis and CT26.WT tumor growth independent from SDF-1. | ||||||||||
| Author: | Kollmar, Otto|Rupertus, Kathrin|Scheuer, Claudia|Nickels, Ruth M|Haberl, Gudrun C Y|Tilton, Bettina|Menger, Michael D|Schilling, Martin K | ||||||||||
| PMID: | 19821487 | ||||||||||
| 49. | |||||||||||
| Journal: | Ann Surg Oncol. 2010 Aug;17(8):2051-8. | ||||||||||
| Title: | Stromal CXCR4 and CXCL12 expression is associated with distant recurrence and poor prognosis in rectal cancer after chemoradiotherapy. | ||||||||||
| Author: | Saigusa, Susumu|Toiyama, Yuji|Tanaka, Koji|Yokoe, Takeshi|Okugawa, Yoshinaga|Kawamoto, Aya|Yasuda, Hiromi|Inoue, Yasuhiro|Miki, Chikao|Kusunoki, Masato | ||||||||||
| PMID: | 20177796 | ||||||||||
| 50. | |||||||||||
| Journal: | Cancer Res. 2010 Jun 1;70(11):4644-54. | ||||||||||
| Title: | Autocrine induction of invasive and metastatic phenotypes by the MIF-CXCR4 axis in drug-resistant human colon cancer cells. | ||||||||||
| Author: | Dessein, Anne-Frederique|Stechly, Laurence|Jonckheere, Nicolas|Dumont, Patrick|Monte, Didier|Leteurtre, Emmanuelle|Truant, Stephanie|Pruvot, Francois-Rene|Figeac, Martin|Hebbar, Mohamed|Lecellier, Charles-Henri|Lesuffleur, Thecla|Dessein, Rodrigue|Grard, | ||||||||||
| PMID: | 20460542 | ||||||||||
| 51. | |||||||||||
| Journal: | Int J Colorectal Dis. 2010 Oct;25(10):1185-91. | ||||||||||
| Title: | Nuclear expression of CXCR4 is associated with advanced colorectal cancer. | ||||||||||
| Author: | Wang, Shang-Chiung|Lin, Jen-Kou|Wang, Huann-Sheng|Yang, Shung-Haur|Li, Anna Fen-Yau|Chang, Shih-Ching | ||||||||||
| PMID: | 20607251 | ||||||||||
| 52. | |||||||||||
| Journal: | Clin Exp Metastasis. 2010 Oct;27(7):517-27. | ||||||||||
| Title: | CD133(+) single cell-derived progenies of colorectal cancer cell line SW480 with different invasive and metastatic potential. | ||||||||||
| Author: | Li, Guangqiu|Liu, Chao|Yuan, Jian|Xiao, Xiaoqin|Tang, Na|Hao, Junmei|Wang, Hongwei|Bian, Xiuwu|Deng, Yongjian|Ding, Yanqing | ||||||||||
| PMID: | 20617370 | ||||||||||
| 53. | |||||||||||
| Journal: | J Clin Invest. 2010 Aug;120(8):2699-714. | ||||||||||
| Title: | Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation. | ||||||||||
| Author: | Imtiyaz, Hongxia Z|Williams, Emily P|Hickey, Michele M|Patel, Shetal A|Durham, Amy C|Yuan, Li-Jun|Hammond, Rachel|Gimotty, Phyllis A|Keith, Brian|Simon, M Celeste | ||||||||||
| PMID: | 20644254 | ||||||||||
| 54. | |||||||||||
| Journal: | J Mol Med (Berl). 2010 Dec;88(12):1243-53. | ||||||||||
| Title: | Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor. | ||||||||||
| Author: | Yadav, Vivek R|Sung, Bokyung|Prasad, Sahdeo|Kannappan, Ramaswamy|Cho, Sung-Gook|Liu, Mingyao|Chaturvedi, Madan M|Aggarwal, Bharat B | ||||||||||
| PMID: | 20798912 | ||||||||||
| 55. | |||||||||||
| Journal: | Mol Cancer. 2010 Oct 14;9:273. | ||||||||||
| Title: | Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12. | ||||||||||
| Author: | Rigo, Antonella|Gottardi, Michele|Zamo, Alberto|Mauri, Pierluigi|Bonifacio, Massimiliano|Krampera, Mauro|Damiani, Ernesto|Pizzolo, Giovanni|Vinante, Fabrizio | ||||||||||
| PMID: | 20946648 | ||||||||||
| 56. | |||||||||||
| Journal: | Clin Dev Immunol. 2010;2010. pii: 537531. | ||||||||||
| Title: | Clinicopathologic significance of HIF-1alpha, CXCR4, and VEGF expression in colon cancer. | ||||||||||
| Author: | Wu, Yugang|Jin, Min|Xu, Huanbai|Shimin, Zhang|He, Songbing|Wang, Liang|Zhang, Yanyun | ||||||||||
| PMID: | 20953377 | ||||||||||
| 57. | |||||||||||
| Journal: | J Surg Res. 2011 Jun 15;168(2):197-205. | ||||||||||
| Title: | Triptolide inhibits proliferation and migration of colon cancer cells by inhibition of cell cycle regulators and cytokine receptors. | ||||||||||
| Author: | Johnson, Sara M|Wang, Xiaofu|Evers, B Mark | ||||||||||
| PMID: | 19922946 | ||||||||||
| 58. | |||||||||||
| Journal: | Dig Dis Sci. 2011 Apr;56(4):1194-200. | ||||||||||
| Title: | The expression of both peroxisome proliferator-activated receptor delta and cyclooxygenase-2 in tissues is associated with poor prognosis in colorectal cancer patients. | ||||||||||
| Author: | Yoshinaga, Masahiro|Taki, Kentaro|Somada, Shinichi|Sakiyama, Yumiko|Kubo, Norihiko|Kaku, Toyoma|Tsuruta, Satoru|Kusumoto, Tetsuya|Sakai, Hironori|Nakamura, Kazuhiko|Takayanagi, Ryoichi|Muto, Yoichi | ||||||||||
| PMID: | 20824502 | ||||||||||
| 59. | |||||||||||
| Journal: | Tumour Biol. 2011 Feb;32(1):189-96. | ||||||||||
| Title: | Changes in CXCL12/CXCR4-chemokine expression during onset of colorectal malignancies. | ||||||||||
| Author: | Oliveira Frick, Vilma|Rubie, Claudia|Ghadjar, Pirus|Faust, Sabrina K|Wagner, Mathias|Graber, Stefan|Schilling, Martin K | ||||||||||
| PMID: | 20865359 | ||||||||||
| 60. | |||||||||||
| Journal: | J Transl Med. 2011 Feb 24;9:22. | ||||||||||
| Title: | CXC receptor-4 mRNA silencing abrogates CXCL12-induced migration of colorectal cancer cells. | ||||||||||
| Author: | Rubie, Claudia|Frick, Vilma O|Ghadjar, Pirus|Wagner, Mathias|Justinger, Christoph|Faust, Sabrina K|Vicinus, Benjamin|Graber, Stefan|Kollmar, Otto|Schilling, Martin K | ||||||||||
| PMID: | 21349176 | ||||||||||
| 61. | |||||||||||
| Journal: | World J Gastroenterol. 2011 Feb 7;17(5):625-32. | ||||||||||
| Title: | Influence of CXCR4/SDF-1 axis on E-cadherin/beta-catenin complex expression in HT29 colon cancer cells. | ||||||||||
| Author: | Wang, Lin|Li, Cui-Ling|Wang, Lei|Yu, Wen-Bin|Yin, Hai-Peng|Zhang, Guang-Yong|Zhang, Li-Feng|Li, Sheng|Hu, San-Yuan | ||||||||||
| PMID: | 21350711 | ||||||||||
| 62. | |||||||||||
| Journal: | J Nucl Med. 2011 Jun;52(6):986-93. | ||||||||||
| Title: | Imaging CXCR4 expression in human cancer xenografts: evaluation of monocyclam 64Cu-AMD3465. | ||||||||||
| Author: | De Silva, Ravindra A|Peyre, Kevin|Pullambhatla, Mrudula|Fox, James J|Pomper, Martin G|Nimmagadda, Sridhar | ||||||||||
| PMID: | 21622896 | ||||||||||
| 63. | |||||||||||
| Journal: | Cancer Manag Res. 2011;3:301-9. | ||||||||||
| Title: | Effects of CXCR4 siRNA/dextran-spermine nanoparticles on CXCR4 expression and serum LDH levels in a mouse model of colorectal cancer metastasis to the liver. | ||||||||||
| Author: | Abedini, Fatemeh|Ismail, Maznah|Hosseinkhani, Hossein|Ibrahim, Tengku Azmi Tengku|Omar, Abdul Rahman|Chong, Pei Pei|Bejo, Mohd Hair|Domb, Abraham J | ||||||||||
| PMID: | 21931504 | ||||||||||
| 64. | |||||||||||
| Journal: | Neoplasia. 2011 Sep;13(9):874-86. | ||||||||||
| Title: | Lymph node stromal cells enhance drug-resistant colon cancer cell tumor formation through SDF-1alpha/CXCR4 paracrine signaling. | ||||||||||
| Author: | Margolin, David A|Silinsky, Jennifer|Grimes, Chelsea|Spencer, Nakia|Aycock, Melissa|Green, Heather|Cordova, Jose|Davis, Nancy K|Driscoll, Tiffany|Li, Li | ||||||||||
| PMID: | 21969820 | ||||||||||
| 65. | |||||||||||
| Journal: | Onkologie. 2011;34(10):502-8. | ||||||||||
| Title: | A Lentiviral CXCR4 overexpression and knockdown model in colorectal cancer cell lines reveals plerixafor-dependent suppression of SDF-1alpha-induced migration and invasion. | ||||||||||
| Author: | Heckmann, Doreen|Laufs, Stephanie|Maier, Patrick|Zucknick, Manuela|Giordano, Frank A|Veldwijk, Marlon R|Eckstein, Volker|Wenz, Frederik|Zeller, W Jens|Fruehauf, Stefan|Allgayer, Heike | ||||||||||
| PMID: | 21985848 | ||||||||||
| 66. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17655-60. | ||||||||||
| Title: | Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways. | ||||||||||
| Author: | Drury, Luke J|Ziarek, Joshua J|Gravel, Stephanie|Veldkamp, Christopher T|Takekoshi, Tomonori|Hwang, Samuel T|Heveker, Nikolaus|Volkman, Brian F|Dwinell, Michael B | ||||||||||
| PMID: | 21990345 | ||||||||||
| 67. | |||||||||||
| Journal: | PLoS One. 2011;6(12):e27399. | ||||||||||
| Title: | Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. | ||||||||||
| Author: | Xu, Huanbai|Wu, Qiong|Dang, Shipeng|Jin, Min|Xu, Jingwei|Cheng, Yiji|Pan, Minglin|Wu, Yugang|Zhang, Chunhui|Zhang, Yanyun | ||||||||||
| PMID: | 22180778 | ||||||||||
| 68. | |||||||||||
| Journal: | Invest New Drugs. 2012 Apr;30(2):508-17. | ||||||||||
| Title: | Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer. | ||||||||||
| Author: | Ma, Lixin|Qiao, Haiquan|He, Changjun|Yang, Qian|Cheung, Chun Hei Antonio|Kanwar, Jagat R|Sun, Xueying | ||||||||||
| PMID: | 21080209 | ||||||||||
| 69. | |||||||||||
| Journal: | J Cell Physiol. 2012 Mar;227(3):1114-22. | ||||||||||
| Title: | Stromal cell-derived factor-1/CXC receptor 4 and beta1 integrin interaction regulates urokinase-type plasminogen activator expression in human colorectal cancer cells. | ||||||||||
| Author: | Huang, Wen-Shih|Chin, Chih-Chien|Chen, Cheng-Nan|Kuo, Yi-Hung|Chen, Te-Chuan|Yu, Hong-Ren|Tung, Shui-Yi|Shen, Chien-Heng|Hsieh, Yung-Yu|Guo, Su-Er|Shi, Chung-Sheng|Liu, Ta-Ju|Kuo, Hsing-Chun | ||||||||||
| PMID: | 21567400 | ||||||||||
| 70. | |||||||||||
| Journal: | Ann Surg Oncol. 2012 Jul;19 Suppl 3:S339-46. | ||||||||||
| Title: | CXCR4 expression predicts patient outcome and recurrence patterns after hepatic resection for colorectal liver metastases. | ||||||||||
| Author: | Yopp, Adam C|Shia, Jinru|Butte, Jean M|Allen, Peter J|Fong, Yuman|Jarnagin, William R|DeMatteo, Ronald P|D'Angelica, Michael I | ||||||||||
| PMID: | 21584832 | ||||||||||
| 71. | |||||||||||
| Journal: | J Oncol. 2012;2012:196957. | ||||||||||
| Title: | Bone Marrow Suppression by c-Kit Blockade Enhances Tumor Growth of Colorectal Metastases through the Action of Stromal Cell-Derived Factor-1. | ||||||||||
| Author: | Rupertus, Kathrin|Haberl, Gudrun C Y|Scheuer, Claudia|Menger, Michael D|Schilling, Martin K|Kollmar, Otto | ||||||||||
| PMID: | 21977032 | ||||||||||
| 72. | |||||||||||
| Journal: | Br J Nutr. 2012 Jun;107(11):1623-34. | ||||||||||
| Title: | Oral inoculation of probiotics Lactobacillus acidophilus NCFM suppresses tumour growth both in segmental orthotopic colon cancer and extra-intestinal tissue. | ||||||||||
| Author: | Chen, Chien-Chang|Lin, Wei-Chuan|Kong, Man-Shan|Shi, Hai Ning|Walker, W Allan|Lin, Chun-Yen|Huang, Ching-Tai|Lin, Yung-Chang|Jung, Shih-Ming|Lin, Tzou-Yien | ||||||||||
| PMID: | 21992995 | ||||||||||
| 73. | |||||||||||
| Journal: | Clin Exp Metastasis. 2012 Feb;29(2):101-10. | ||||||||||
| Title: | CXCR4/CXCL12 expression profile is associated with tumor microenvironment and clinical outcome of liver metastases of colorectal cancer. | ||||||||||
| Author: | Sakai, Nozomu|Yoshidome, Hiroyuki|Shida, Takashi|Kimura, Fumio|Shimizu, Hiroaki|Ohtsuka, Masayuki|Takeuchi, Dan|Sakakibara, Masahiro|Miyazaki, Masaru | ||||||||||
| PMID: | 22075627 | ||||||||||
| 74. | |||||||||||
| Journal: | Lab Invest. 2012 Mar;92(3):420-36. | ||||||||||
| Title: | CD133+ colon cancer cells are more interactive with the tumor microenvironment than CD133- cells. | ||||||||||
| Author: | Chao, Celia|Carmical, J Russ|Ives, Kirk L|Wood, Thomas G|Aronson, Judith F|Gomez, Guillermo A|Djukom, Clarisse D|Hellmich, Mark R | ||||||||||
| PMID: | 22157717 | ||||||||||
| 75. | |||||||||||
| Journal: | Curr Mol Med. 2012 Feb;12(2):153-62. | ||||||||||
| Title: | Xanthohumol, a prenylated chalcone derived from hops, suppresses cancer cell invasion through inhibiting the expression of CXCR4 chemokine receptor. | ||||||||||
| Author: | Wang, Y|Chen, Y|Wang, J|Chen, J|Aggarwal, B B|Pang, X|Liu, M | ||||||||||
| PMID: | 22172099 | ||||||||||
| 76. | |||||||||||
| Journal: | Cancer Invest. 2012 Jun;30(5):380-9. | ||||||||||
| Title: | Inhibiting CD164 expression in colon cancer cell line HCT116 leads to reduced cancer cell proliferation, mobility, and metastasis in vitro and in vivo. | ||||||||||
| Author: | Tang, Jingqun|Zhang, Liyang|She, Xiaoling|Zhou, Guangqian|Yu, Fenglei|Xiang, Juanjuan|Li, Gang | ||||||||||
| PMID: | 22409183 | ||||||||||
| 77. | |||||||||||
| Journal: | J Korean Soc Coloproctol. 2012 Feb;28(1):3-4. | ||||||||||
| Title: | Will the Stroma-derived Factor-1alpha (CXCL12)/CXCR4 Pathway Become a Major Concern for Advanced Colorectal Cancer? | ||||||||||
| Author: | Kim, Hungdai | ||||||||||
| PMID: | 22413073 | ||||||||||
| 78. | |||||||||||
| Journal: | BMC Cancer. 2012 Mar 20;12:96. | ||||||||||
| Title: | Characterization of colon cancer cells: a functional approach characterizing CD133 as a potential stem cell marker. | ||||||||||
| Author: | Schneider, Meike|Huber, Johannes|Hadaschik, Boris|Siegers, Gabrielle M|Fiebig, Heinz-Herbert|Schuler, Julia | ||||||||||
| PMID: | 22433494 | ||||||||||
| 79. | |||||||||||
| Journal: | BMC Gastroenterol. 2012 May 28;12:53. | ||||||||||
| Title: | The balance between two isoforms of LEF-1 regulates colon carcinoma growth. | ||||||||||
| Author: | Wang, Shu-Hong|Nan, Ke-Jun|Wang, Yao-Chun|Wang, Wen-Juan|Tian, Tao | ||||||||||
| PMID: | 22639890 | ||||||||||
| 80. | |||||||||||
| Journal: | Mol Cancer Ther. 2012 Nov;11(11):2516-25. | ||||||||||
| Title: | A locked, dimeric CXCL12 variant effectively inhibits pulmonary metastasis of CXCR4-expressing melanoma cells due to enhanced serum stability. | ||||||||||
| Author: | Takekoshi, Tomonori|Ziarek, Joshua J|Volkman, Brian F|Hwang, Sam T | ||||||||||
| PMID: | 22869557 | ||||||||||
| 81. | |||||||||||
| Journal: | BMC Med. 2012 Aug 7;10:85. | ||||||||||
| Title: | CD133(+)CXCR4(+) colon cancer cells exhibit metastatic potential and predict poor prognosis of patients. | ||||||||||
| Author: | Zhang, Shan-shan|Han, Zhi-peng|Jing, Ying-ying|Tao, Shuang-fen|Li, Tie-jun|Wang, Hao|Wang, Yang|Li, Rong|Yang, Yang|Zhao, Xue|Xu, Xiao-dong|Yu, En-da|Rui, Yao-cheng|Liu, Hou-jia|Zhang, Li|Wei, Li-xin | ||||||||||
| PMID: | 22871210 | ||||||||||
| 82. | |||||||||||
| Journal: | Int J Nanomedicine. 2012;7:4159-68. | ||||||||||
| Title: | Cationized dextran nanoparticle-encapsulated CXCR4-siRNA enhanced correlation between CXCR4 expression and serum alkaline phosphatase in a mouse model of colorectal cancer. | ||||||||||
| Author: | Abedini, Fatemeh|Hosseinkhani, Hossein|Ismail, Maznah|Domb, Abraham J|Omar, Abdul Rahman|Chong, Pei Pei|Hong, Po-Da|Yu, Dah-Shyong|Farber, Ira-Yudovin | ||||||||||
| PMID: | 22888250 | ||||||||||
| 83. | |||||||||||
| Journal: | Int J Nanomedicine. 2012;7:4533-44. | ||||||||||
| Title: | |||||||||||