Primary Site >> Colorectal Cancer
Gene >> CXCR4
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Ref: Gene expression profiling in silico: relative expression of candidate angiogenesis associated genes in renal cell carcinomas. PMID: 11937758 Ref: Transepithelial transport of HIV-1 by M cells is receptor-mediated. PMID: 12093918 Ref: Adaptation of a CXCR4-using human immunodeficiency type 1 NDK virus in intestinal cells is associated with CD4-independent replication. PMID: 12504579 |
Ref: The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases. PMID: 12839981 |
Ref: Inhibitory effects of anti-CXCR4 antibodies on human colon cancer cells. PMID: 15592929 Ref: Effect of chemokine receptors CXCR4 and CCR7 on the metastatic behavior of human colorectal cancer. PMID: 15755995 Ref: Prediction of lymph node metastasis in colorectal carcinoma by expressionof chemokine receptor CCR7. PMID: 15828050 Ref: Chemokine receptor CXCR4 expression in colorectal cancer patients increases the risk for recurrence and for poor survival. PMID: 15837989 Ref: Dendritic cells and vascular endothelial growth factor in colorectal cancer: correlations with clinicobiological findings. PMID: 16015045 Ref: CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation. PMID: 16125170 |
Ref: Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis. PMID: 16568088 Ref: Involvement of chemokine receptor CCR6 in colorectal cancer metastasis. PMID: 16641550 Ref: Overexpression of both CXC chemokine receptor 4 and vascular endothelial growth factor proteins predicts early distant relapse in stage II-III colorectal cancer patients. PMID: 16675573 Ref: In vivo luminescent imaging of cyclosporin A-mediated cancer progression in rats. PMID: 16770245 Ref: Chemokine receptor CXCR4 expression in patients with melanoma and colorectal cancer liver metastases and the association with disease outcome. PMID: 16794396 Ref: Adenosine upregulates CXCR4 and enhances the proliferative and migratory responses of human carcinoma cells to CXCL12/SDF-1alpha. PMID: 16823836 Ref: Chemokine expression in hepatocellular carcinoma versus colorectal liver metastases. PMID: 17075975 Ref: Association between expression of vascular endothelial growth factor C, chemokine receptor CXCR4 and lymph node metastasis in colorectal cancer. PMID: 17641542 |
Ref: Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion. PMID: 17130833 Ref: Polymorphism and circulating levels of the chemokine CXCL12 in colorectal cancer patients. PMID: 17143542 Ref: Chemokine receptor CXCR3 promotes colon cancer metastasis to lymph nodes. PMID: 17297455 Ref: Thiazolidinedione drugs down-regulate CXCR4 expression on human colorectal cancer cells in a peroxisome proliferator activated receptor gamma-dependent manner. PMID: 17390024 Ref: 15-Deoxy-delta(12,14)-prostaglandin J(2) down-regulates CXCR4 on carcinoma cells through PPARgamma- and NFkappaB-mediated pathways. PMID: 17707368 Ref: Chemokine receptors in cancer metastasis and cancer cell-derived chemokines in host immune response. PMID: 17894551 |
Ref: Inhibition of CXCR4 activity with AMD3100 decreases invasion of human colorectal cancer cells in vitro. PMID: 18416455 Ref: Expression of SDF-1 alpha and nuclear CXCR4 predicts lymph node metastasis in colorectal cancer. PMID: 18443596 Ref: Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells. PMID: 18558091 Ref: [Expression of chemokine receptor CXCR4 in colorectal carcinoma and its relationship with clinicopathological parameters]. PMID: 18803056 Ref: Differential CXC receptor expression in colorectal carcinomas. PMID: 18959627 |
Ref: Expression and function of T cell homing molecules in Hodgkin's lymphoma. PMID: 18488221 Ref: CXCR-4 knockdown by small interfering RNA inhibits cell proliferation and invasion of oral squamous cell carcinoma cells. PMID: 18624931 Ref: A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration. PMID: 19305148 Ref: Nuclear localization of CXCR4 determines prognosis for colorectal cancer patients. PMID: 19308676 Ref: Brain metastases from colorectal cancer: risk factors, incidence, and the possible role of chemokines. PMID: 19423503 Ref: SDF-1alpha G801A polymorphism predicts lymph node metastasis in stage T3 colorectal cancer. PMID: 19472013 Ref: [Effect of stromal cell-derived factor-1 and its receptor CXCR4 on liver metastasis of human colon cancer]. PMID: 19563077 Ref: CXCR4 regulates the early extravasation of metastatic tumor cells in vivo. PMID: 19568410 Ref: Hepatic stellate cells promote liver metastasis of colon cancer cells by the action of SDF-1/CXCR4 axis. PMID: 19588204 Ref: [Association of CXCR4 and SDF-1alpha with organ-specific metastasis of nasopharyngeal carcinoma]. PMID: 19615279 Ref: Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model. PMID: 19623659 Ref: CXCL12, CXCR4 and CXCR7 expression in brain metastases. PMID: 19625779 Ref: Brain metastases from colorectal cancer: risk factors, incidence, and the possible role of chemokines. PMID: 19739271 Ref: Direct evidence that bevacizumab, an anti-VEGF antibody, up-regulates SDF1alpha, CXCR4, CXCL6, and neuropilin 1 in tumors from patients with rectal cancer. PMID: 19826039 Ref: The role of vascular CXCR4 expression in colorectal carcinoma. PMID: 19912363 Ref: [Shikonin down-regulates CXCR4 expression and inhibits CXCL12-induced migratory responses in colorectal carcinoma cell line SW480]. PMID: 19921580 Ref: HIV Nef-M1 Effects on Colorectal Cancer Growth in Tumor-induced Spleens and Hepatic Metastasis. PMID: 20383296 |
Ref: Aberrant DNA methylation occurs in colon neoplasms arising in the azoxymethane colon cancer model. PMID: 19777566 Ref: CXCR4 and CXCR7 regulate angiogenesis and CT26.WT tumor growth independent from SDF-1. PMID: 19821487 Ref: Stromal CXCR4 and CXCL12 expression is associated with distant recurrence and poor prognosis in rectal cancer after chemoradiotherapy. PMID: 20177796 Ref: Autocrine induction of invasive and metastatic phenotypes by the MIF-CXCR4 axis in drug-resistant human colon cancer cells. PMID: 20460542 Ref: Nuclear expression of CXCR4 is associated with advanced colorectal cancer. PMID: 20607251 Ref: CD133(+) single cell-derived progenies of colorectal cancer cell line SW480 with different invasive and metastatic potential. PMID: 20617370 Ref: Hypoxia-inducible factor 2alpha regulates macrophage function in mouse models of acute and tumor inflammation. PMID: 20644254 Ref: Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor. PMID: 20798912 Ref: Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12. PMID: 20946648 Ref: Clinicopathologic significance of HIF-1alpha, CXCR4, and VEGF expression in colon cancer. PMID: 20953377 |
Ref: Triptolide inhibits proliferation and migration of colon cancer cells by inhibition of cell cycle regulators and cytokine receptors. PMID: 19922946 Ref: The expression of both peroxisome proliferator-activated receptor delta and cyclooxygenase-2 in tissues is associated with poor prognosis in colorectal cancer patients. PMID: 20824502 Ref: Changes in CXCL12/CXCR4-chemokine expression during onset of colorectal malignancies. PMID: 20865359 Ref: CXC receptor-4 mRNA silencing abrogates CXCL12-induced migration of colorectal cancer cells. PMID: 21349176 Ref: Influence of CXCR4/SDF-1 axis on E-cadherin/beta-catenin complex expression in HT29 colon cancer cells. PMID: 21350711 Ref: Imaging CXCR4 expression in human cancer xenografts: evaluation of monocyclam 64Cu-AMD3465. PMID: 21622896 Ref: Effects of CXCR4 siRNA/dextran-spermine nanoparticles on CXCR4 expression and serum LDH levels in a mouse model of colorectal cancer metastasis to the liver. PMID: 21931504 Ref: Lymph node stromal cells enhance drug-resistant colon cancer cell tumor formation through SDF-1alpha/CXCR4 paracrine signaling. PMID: 21969820 Ref: A Lentiviral CXCR4 overexpression and knockdown model in colorectal cancer cell lines reveals plerixafor-dependent suppression of SDF-1alpha-induced migration and invasion. PMID: 21985848 Ref: Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways. PMID: 21990345 Ref: Alteration of CXCR7 expression mediated by TLR4 promotes tumor cell proliferation and migration in human colorectal carcinoma. PMID: 22180778 |
Ref: Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer. PMID: 21080209 Ref: Stromal cell-derived factor-1/CXC receptor 4 and beta1 integrin interaction regulates urokinase-type plasminogen activator expression in human colorectal cancer cells. PMID: 21567400 Ref: CXCR4 expression predicts patient outcome and recurrence patterns after hepatic resection for colorectal liver metastases. PMID: 21584832 Ref: Bone Marrow Suppression by c-Kit Blockade Enhances Tumor Growth of Colorectal Metastases through the Action of Stromal Cell-Derived Factor-1. PMID: 21977032 Ref: Oral inoculation of probiotics Lactobacillus acidophilus NCFM suppresses tumour growth both in segmental orthotopic colon cancer and extra-intestinal tissue. PMID: 21992995 Ref: CXCR4/CXCL12 expression profile is associated with tumor microenvironment and clinical outcome of liver metastases of colorectal cancer. PMID: 22075627 Ref: CD133+ colon cancer cells are more interactive with the tumor microenvironment than CD133- cells. PMID: 22157717 Ref: Xanthohumol, a prenylated chalcone derived from hops, suppresses cancer cell invasion through inhibiting the expression of CXCR4 chemokine receptor. PMID: 22172099 Ref: Inhibiting CD164 expression in colon cancer cell line HCT116 leads to reduced cancer cell proliferation, mobility, and metastasis in vitro and in vivo. PMID: 22409183 Ref: Will the Stroma-derived Factor-1alpha (CXCL12)/CXCR4 Pathway Become a Major Concern for Advanced Colorectal Cancer? PMID: 22413073 Ref: Characterization of colon cancer cells: a functional approach characterizing CD133 as a potential stem cell marker. PMID: 22433494 Ref: The balance between two isoforms of LEF-1 regulates colon carcinoma growth. PMID: 22639890 Ref: A locked, dimeric CXCL12 variant effectively inhibits pulmonary metastasis of CXCR4-expressing melanoma cells due to enhanced serum stability. PMID: 22869557 Ref: CD133(+)CXCR4(+) colon cancer cells exhibit metastatic potential and predict poor prognosis of patients. PMID: 22871210 Ref: Cationized dextran nanoparticle-encapsulated CXCR4-siRNA enhanced correlation between CXCR4 expression and serum alkaline phosphatase in a mouse model of colorectal cancer. PMID: 22888250 Ref: Intracellular CXCR4(+) cell targeting with T22-empowered protein-only nanoparticles. PMID: 22923991 Ref: Co-expression of CXCR4 and CD133 proteins is associated with poor prognosis in stage II-III colon cancer patients. PMID: 22970002 Ref: Stromal cell-derived factor-1alpha and macrophage migration-inhibitory factor induce metastatic behavior in CXCR4-expressing colon cancer cells. PMID: 23023114 Ref: Synergistic antitumor effects of endostar in combination with oxaliplatin via inhibition of HIF and CXCR4 in the colorectal cell line SW1116. PMID: 23071744 Ref: CXC chemokine ligand 12/stromal cell-derived factor-1 regulates cell adhesion in human colon cancer cells by induction of intercellular adhesion molecule-1. PMID: 23098564 |
Ref: The role of CXCR3 and CXCR4 in colorectal cancer metastasis. PMID: 22689289 Ref: Hypoxia enhances colon cancer migration and invasion through promotion of epithelial-mesenchymal transition. PMID: 22959209 Ref: Epigenetic regulation of CXCR4 expression by the ocular microenvironment. PMID: 23188729 Ref: Histone deacetylase inhibitors induce CXCR4 mRNA but antagonize CXCR4 migration. PMID: 23192271 Ref: Celecoxib downregulates CD133 expression through inhibition of the Wnt signaling pathway in colon cancer cells. PMID: 23245395 Ref: Adenovirus-mediated transcriptional targeting of colorectal cancer and effects on treatment-resistant hypoxic cells. PMID: 23313233 Ref: Increased growth of colorectal liver metastasis following partial hepatectomy. PMID: 23385555 Ref: CXCR4 Expression and Treatment with SDF-1alpha or Plerixafor Modulate Proliferation and Chemosensitivity of Colon Cancer Cells. PMID: 23544165 Ref: The use of hypoxic cultured mesenchymal stem cell for oncolytic virus therapy. PMID: 23618949 Ref: Dynamic changes of peritoneal macrophages and subpopulations during ulcerative colitis to metastasis of colorectal carcinoma in a mouse model. PMID: 23625042 Ref: CD49f-positive cell population efficiently enriches colon cancer-initiating cells. PMID: 23708747 Ref: Clinical applications of gene expression in colorectal cancer. PMID: 23730510 Ref: Expression of miR-126 suppresses migration and invasion of colon cancer cells by targeting CXCR4. PMID: 23744532 Ref: The expression of chemokine receptors CCR6, CXCR2 and CXCR4 is not organ-specific for distant metastasis in colorectal cancer: a comparative study. PMID: 23758411 Ref: Nimbolide, a limonoid triterpene, inhibits growth of human colorectal cancer xenografts by suppressing the proinflammatory microenvironment. PMID: 23766363 Ref: CD 133+ and CXCR4+ colon cancer cells as a marker for lymph node metastasis. PMID: 23777983 Ref: Clinicopathologic significance of CXCR4 and Nrf2 in colorectal cancer. PMID: 23885267 Ref: [Expression of molecular markers detected by immunohistochemistry and risk of lymph node metastasis in stage T1 and T2 colorecrectal cancers]. PMID: 23985256 Ref: miR-133b, a muscle-specific microRNA, is a novel prognostic marker that participates in the progression of human colorectal cancer via regulation of CXCR4 expression. PMID: 24330809 Ref: Effect of CO(2) pneumoperitoneum on the expression of the chemokine receptors CXCR4 and CCR7 in colorectal carcinoma cells in vitro. PMID: 24342323 |
Ref: SDF-1/CXCR4 axis promotes directional migration of colorectal cancer cells through upregulation of integrin alphavbeta6. PMID: 24085800 Ref: Rectal cancer: dynamic contrast-enhanced MRI correlates with lymph node status and epidermal growth factor receptor expression. PMID: 24127411 Ref: MicroRNA-126 functions as a tumor suppressor in colorectal cancer cells by targeting CXCR4 via the AKT and ERK1/2 signaling pathways. PMID: 24189753 Ref: The disparate twins: a comparative study of CXCR4 and CXCR7 in SDF-1alpha-induced gene expression, invasion and chemosensitivity of colon cancer. PMID: 24255072 Ref: A prognostic model comprising pT stage, N status, and the chemokine receptors CXCR4 and CXCR7 powerfully predicts outcome in neoadjuvant resistant rectal cancer patients. PMID: 24375277 Ref: CXCR4 as a novel predictive biomarker for metastasis and poor prognosis in colorectal cancer. PMID: 24395653 Ref: The association of CXCR4 expression with prognosis and clinicopathological indicators in colorectal carcinoma patients: a meta-analysis. PMID: 24422942 Ref: Interaction of the chemokines I-TAC (CXCL11) and SDF-1 (CXCL12) in the regulation of tumor angiogenesis of colorectal cancer. PMID: 24493023 Ref: Low expression of microRNA-126 is associated with poor prognosis in colorectal cancer. PMID: 24532280 Ref: Hypoxia differentially regulated CXCR4 and CXCR7 signaling in colon cancer. PMID: 24629239 Ref: The influence of lentivirus-mediated CXCR4 RNA interference on hepatic metastasis of colorectal cancer. PMID: 24647809 Ref: Inhibitor of DNA-binding protein 1 knockdown arrests the growth of colorectal cancer cells and suppresses hepatic metastasis in vivo. PMID: 24804700 Ref: SDF-1/CXCR4 promotes epithelial-mesenchymal transition and progression of colorectal cancer by activation of the Wnt/beta-catenin signaling pathway. PMID: 25150783 Ref: IL-33/ST2 pathway contributes to metastasis of human colorectal cancer. PMID: 25280997 Ref: Hypoxia-inducible factors modulate the stemness and malignancy of colon cancer cells by playing opposite roles in canonical Wnt signaling. PMID: 25396735 Ref: [Expression of methionine sulfoxide reductase in colorectal cancer stem cells in vitro]. PMID: 25413075 |
Ref: Tissue inhibitor of metalloproteinases (TIMP)-1 creates a premetastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil recruitment in mice. PMID: 25131778 Ref: Gene expression differences in primary colorectal tumors and matched liver metastases: chemotherapy related or tumoral heterogeneity? PMID: 25301403 Ref: Higher metastatic efficiency of KRas G12V than KRas G13D in a colorectal cancer model. PMID: 25359494 Ref: Identification of LY2510924, a novel cyclic peptide CXCR4 antagonist that exhibits antitumor activities in solid tumor and breast cancer metastatic models. PMID: 25504752 Ref: CXCR4 and CXCL12 Expression in Rectal Tumors of Stage IV Patients Before and After Local Radiotherapy and Systemic Neoadjuvant Treatment. PMID: 25557636 Ref: Overexpression of chemokine receptor CXCR2 and ligand CXCL7 in liver metastases from colon cancer is correlated to shorter disease-free and overall survival. PMID: 25580640 Ref: CXCR4 over-expression and survival in cancer: a system review and meta-analysis. PMID: 25669980 Ref: Effect of CXCR4 and CD133 co-expression on the prognosis of patients with stage II~III colon cancer. PMID: 25735334 Ref: Investigation of the roles of exosomes in colorectal cancer liver metastasis. PMID: 25760247 Ref: Activation of platelet protease-activated receptor-1 induces epithelial-mesenchymal transition and chemotaxis of colon cancer cell line SW620. PMID: 25846512 Ref: SEMA3F prevents metastasis of colorectal cancer by PI3K-AKT-dependent down-regulation of the ASCL2-CXCR4 axis. PMID: 25866254 Ref: Curcumin potentiates antitumor activity of 5-fluorouracil in a 3D alginate tumor microenvironment of colorectal cancer. PMID: 25884903 Ref: TFF2-CXCR4 Axis Is Associated with BRAF V600E Colon Cancer. PMID: 25899003 Ref: Downregulation of the CXCR4/CXCL12 axis blocks the activation of the Wnt/beta-catenin pathway in human colon cancer cells. PMID: 25960214 Ref: The critical roles of tumor-initiating cells and the lymph node stromal microenvironment in human colorectal cancer extranodal metastasis using a unique humanized orthotopic mouse model. PMID: 25962655 Ref: Prognosis and Clinicopathology of CXCR4 in Colorectal Cancer Patients: a Meta-analysis. PMID: 25987090 Ref: Identification of a distinct population of CD133(+)CXCR4(+) cancer stem cells in ovarian cancer. PMID: 26020117 Ref: Role of B7-H4 siRNA in Proliferation, Migration, and Invasion of LOVO Colorectal Carcinoma Cell Line. PMID: 26078947 Ref: Nef-M1, a peptide antagonist of CXCR4, inhibits tumor angiogenesis and epithelialtomesenchymal transition in colon and breast cancers. PMID: 26318034 Ref: [The metastatic niche. Mechanisms and prognostic implications]. PMID: 26395891 Ref: Stromal cell derived factor-1 and CXCR4 expression in colorectal cancer promote liver metastasis. PMID: 26406413 Ref: Chemotherapeutic agents attenuate CXCL12-mediated migration of colon cancer cells by selecting for CXCR4-negative cells and increasing peptidase CD26. PMID: 26552750 Ref: [Prognostic values of the clinical, morphological and molecular biological characteristics of colon adenocarcinoma]. PMID: 26978017 |
Ref: CXCR4, CXCL12 and the relative CXCL12-CXCR4 expression as prognostic factors in colon cancer. PMID: 26678887 Ref: Angiogenesis-Related Markers and Prognosis After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Metastatic Colorectal Cancer. PMID: 26727921 Ref: Peritoneal Dissemination Requires an Sp1-Dependent CXCR4/CXCL12 Signaling Axis and Extracellular Matrix-Directed Spheroid Formation. PMID: 26744523 Ref: Neural innervation stimulates splenic TFF2 to arrest myeloid cell expansion and cancer. PMID: 26841680 Ref: Inhibition of Growth and Metastasis of Colon Cancer by Delivering 5-Fluorouracil-loaded Pluronic P85 Copolymer Micelles. PMID: 26864651 Ref: Sirt1 Is Required for Resveratrol-Mediated Chemopreventive Effects in Colorectal Cancer Cells. PMID: 26959057 Ref: Curcumin inhibits tumor epithelialmesenchymal transition by downregulating the Wnt signaling pathway and upregulating NKD2 expression in colon cancer cells. PMID: 26985708 Ref: Analysis of the expression of SDF-1 splicing variants in human colorectal cancer and normal mucosa tissues. PMID: 26998092 Ref: Structural and functional features of self-assembling protein nanoparticles produced in endotoxin-free Escherichia coli. PMID: 27059706 Ref: Cancer-specific uptake of a liganded protein nanocarrier targeting aggressive CXCR4(+) colorectal cancer models. PMID: 27085904 Ref: Ex-vivo characterization of circulating colon cancer cells distinguished in stem and differentiated subset provides useful biomarker for personalized metastatic risk assessment. PMID: 27176720 Ref: The Effect of Analogues of 1alpha,25-Dihydroxyvitamin D(2) on the Regrowth and Gene Expression of Human Colon Cancer Cells Refractory to 5-Fluorouracil. PMID: 27314328 Ref: The prognostic role of serum C-X-C chemokine receptor type 4 in patients with metastatic or recurrent colorectal cancer. PMID: 27330310 Ref: High expression of WISP1 in colon cancer is associated with apoptosis, invasion and poor prognosis. PMID: 27409174 Ref: MicroRNA-126 inhibits colon cancer cell proliferation and invasion by targeting the chemokine (C-X-C motif) receptor 4 and Ras homolog gene family, member A, signaling pathway. PMID: 27517626 Ref: Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists. PMID: 27571038 Ref: gamma-Tocotrienol suppresses growth and sensitises human colorectal tumours to capecitabine in a nude mouse xenograft model by down-regulating multiple molecules. PMID: 27575851 Ref: BACH1 silencing by siRNA inhibits migration of HT-29 colon cancer cells through reduction of metastasis-related genes. PMID: 27657827 Ref: The Association of CXC Receptor 4 Mediated Signaling Pathway with Oxaliplatin-Resistant Human Colorectal Cancer Cells. PMID: 27668882 Ref: Co-expression of Lgr5 and CXCR4 characterizes cancer stem-like cells of colorectal cancer. PMID: 27835894 Ref: Prognostic significance of USP33 in advanced colorectal cancer patients: new insights into beta-arrestin-dependent ERK signaling. PMID: 27835898 Ref: CXCR4-CXCL12-CXCR7, TLR2-TLR4, and PD-1/PD-L1 in colorectal cancer liver metastases from neoadjuvant-treated patients. PMID: 28123896 Ref: Explaining the Paucity of Intratumoral T Cells: A Construction Out of Known Entities. PMID: 28389597 |
Ref: LPS-induced CXCR4-dependent migratory properties and a mesenchymal-like phenotype of colorectal cancer cells. PMID: 26745593 Ref: Onbaekwon Suppresses Colon Cancer Cell Invasion by Inhibiting Expression of the CXC Chemokine Receptor 4. PMID: 27160279 Ref: Garcinol exhibits anti-proliferative activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells. PMID: 27481098 Ref: ADAM17 is a Tumor Promoter and Therapeutic Target in Western Diet-associated Colon Cancer. PMID: 27489286 Ref: Role of Stem Cells in Colorectal Cancer Progression and Prognostic and Predictive Characteristics of Stem Cell Markers in Colorectal Cancer. PMID: 27593447 Ref: Activation of CXCL12/CXCR4 renders colorectal cancer cells less sensitive to radiotherapy via up-regulating the expression of survivin. PMID: 27798120 Ref: miR-663a regulates growth of colon cancer cells, after administration of antimicrobial peptides, by targeting CXCR4-p21 pathway. PMID: 28061765 Ref: CXCL12/CXCR4 axis induced miR-125b promotes invasion and confers 5-fluorouracil resistance through enhancing autophagy in colorectal cancer. PMID: 28176874 Ref: Expression of CXCR-4 and IDO in human colorectal cancer: An immunohistochemical approach. PMID: 28515923 Ref: Methanolic extract of Boswellia serrata exhibits anti-cancer activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells. PMID: 28549801 Ref: Clinicopathologic and prognostic significance of immunohistochemical expression of HIF-1alpha, CXCR4 and CA9 in colorectal carcinoma. PMID: 28554753 Ref: Role of CXCR4 and SDF1 as prognostic factors for survival and the association with clinicopathology in colorectal cancer: A systematic meta-analysis. PMID: 28621237 Ref: The Axis of CXCR4/SDF-1 Plays a Role in Colon Cancer Cell Adhesion Through Regulation of the AKT and IGF1R Signalling Pathways. PMID: 28739729 Ref: Targeting CXCR4-dependent immunosuppressive Ly6C(low) monocytes improves antiangiogenic therapy in colorectal cancer. PMID: 28900008 Ref: Identification of hypoxia-regulated angiogenic genes in colorectal cancer. PMID: 28928094 Ref: Phosphorylated CXCR4 expression has a positive prognostic impact in colorectal cancer. PMID: 28936810 Ref: Ginkgolic acid inhibits the invasiveness of colon cancer cells through AMPK activation. PMID: 29113214 Ref: Effect of AICAR and 5-Fluorouracil on X-ray Repair, Cross-Complementing Group 1 Expression, and Consequent Cytotoxicity Regulation in Human HCT-116 Colorectal Cancer Cells. PMID: 29117108 |
Ref: Mst1 regulates colorectal cancer stress response via inhibiting Bnip3-related mitophagy by activation of JNK/p53 pathway. PMID: 29063978 Ref: ALDH1A3 affects colon cancer in vitro proliferation and invasion depending on CXCR4 status. PMID: 29235568 Ref: Identification of crucial genes associated with Parkinson's disease using microarray data. PMID: 29257331 Ref: Self-assembling toxin-based nanoparticles as self-delivered antitumoral drugs. PMID: 29408658 Ref: CXCR4 receptor blockage reduces the contribution of tumor and stromal cells to the metastatic growth in the liver. PMID: 29436696 Ref: BACH1 promotes the progression of human colorectal cancer through BACH1/CXCR4 pathway. PMID: 29481800 Ref: Release of targeted protein nanoparticles from functional bacterial amyloids: A death star-like approach. PMID: 29641987 Ref: Loss of neutrophil polarization in colon carcinoma liver metastases of mice with an inducible, liver-specific IGF-I deficiency. PMID: 29644002 Ref: CXCR4 overexpression is correlated with poor prognosis in colorectal cancer. PMID: 29719205 Ref: Expression Patterns of CXCL12 and its Receptor in Colorectal Carcinoma. PMID: 29739049 Ref: Clinicopathologic Significance of CXCL12 and CXCR4 Expressions in Patients with Colorectal Cancer. PMID: 29887884 Ref: Laminin alpha1 orchestrates VEGFA functions in the ecosystem of colorectal carcinoma. PMID: 29907957 Ref: Resveratrol Chemosensitizes TNF-beta-Induced Survival of 5-FU-Treated Colorectal Cancer Cells. PMID: 30002278 Ref: Sulforaphane, a Chemopreventive Compound, Inhibits Cyclooxygenase-2 and Microsomal Prostaglandin E Synthase-1 Expression in Human HT-29 Colon Cancer Cells. PMID: 30041241 Ref: CXCR3 expression in colorectal cancer cells enhanced invasion through preventing CXCR4 internalization. PMID: 30092218 Ref: ALDH1A3 upregulation and spontaneous metastasis formation is associated with acquired chemoresistance in colorectal cancer cells. PMID: 30143021 Ref: Selective depletion of metastatic stem cells as therapy for human colorectal cancer. PMID: 30190334 Ref: A Unique Non-Saccharide Mimetic of Heparin Hexasaccharide Inhibits Colon Cancer Stem Cells via p38 MAP Kinase Activation. PMID: 30337351 Ref: CXCR7/CXCR4 heterodimer-induced histone demethylation: a new mechanism of colorectal tumorigenesis. PMID: 30337690 Ref: Integrin alphavbeta6 Plays an Bi-directional Regulation Role Between Colon Cancer cells and Cancer-Associated Fibroblasts. PMID: 30355650 Ref: Knockdown of MON1B Exerts Anti-Tumor Effects in Colon Cancer In Vitro. PMID: 30368516 |