Literatures

Primary Site >> Colorectal Cancer

Gene >> CXCL12

1.
Journal:	Int J Cancer. 1997 Nov 27;73(5):656-62.
Title:	Reduced expression of the CXC chemokine hIRH/SDF-1alpha mRNA in hepatoma and digestive tract cancer.
Author:	Shibuta, K\|Begum, N A\|Mori, M\|Shimoda, K\|Akiyoshi, T\|Barnard, G F
PMID:	9398042

2.
Journal:	Cancer Res. 2003 Jul 1;63(13):3833-9.
Title:	The chemokine receptor CXCR4 is required for outgrowth of colon carcinoma micrometastases.
Author:	Zeelenberg, Ingrid S\|Ruuls-Van Stalle, Lisette\|Roos, Ed
PMID:	12839981

3.
Journal:	Cancer Immunol Immunother. 2005 Aug;54(8):781-91. Epub 2004 Dec 11.
Title:	Inhibitory effects of anti-CXCR4 antibodies on human colon cancer cells.
Author:	Ottaiano, Alessandro\|di Palma, Antonella\|Napolitano, Maria\|Pisano, Carmen\|Pignata, Sandro\|Tatangelo, Fabiana\|Botti, Gerardo\|Acquaviva, Angela Maria\|Castello, Giuseppe\|Ascierto, Paolo Antonio\|Iaffaioli, Rosario Vincenzo\|Scala, Stefania
PMID:	15592929

4.
Journal:	J Clin Oncol. 2005 Apr 20;23(12):2744-53.
Title:	Chemokine receptor CXCR4 expression in colorectal cancer patients increases the risk for recurrence and for poor survival.
Author:	Kim, Joseph\|Takeuchi, Hiroya\|Lam, Stella T\|Turner, Roderick R\|Wang, He-Jing\|Kuo, Christine\|Foshag, Leland\|Bilchik, Anton J\|Hoon, Dave S B
PMID:	15837989

5.
Journal:	Exp Cell Res. 2005 Oct 15;310(1):117-30.
Title:	CXCR4 and CXCL12 are inversely expressed in colorectal cancer cells and modulate cancer cell migration, invasion and MMP-9 activation.
Author:	Brand, Stephan\|Dambacher, Julia\|Beigel, Florian\|Olszak, Torsten\|Diebold, Joachim\|Otte, Jan-Michel\|Goke, Burkhard\|Eichhorst, Soren T
PMID:	16125170

6.
Journal:	Biochem Biophys Res Commun. 2006 Feb 17;340(3):758-66.
Title:	Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers.
Author:	Chen, Yongxin\|Guo, Yingqiu\|Ge, Xijin\|Itoh, Hirotaka\|Watanabe, Akira\|Fujiwara, Takeshi\|Kodama, Tatsuhiko\|Aburatani, Hiroyuki
PMID:	16380080

7.
Journal:	Oncogene. 2006 Aug 17;25(36):4986-97. Epub 2006 Mar 27.
Title:	Silencing of epithelial CXCL12 expression by DNA hypermethylation promotes colonic carcinoma metastasis.
Author:	Wendt, M K\|Johanesen, P A\|Kang-Decker, N\|Binion, D G\|Shah, V\|Dwinell, M B
PMID:	16568088

8.
Journal:	Cancer Res. 2006 Apr 1;66(7):3513-22.
Title:	Adenoviral gene transfer of stromal cell-derived factor-1 to murine tumors induces the accumulation of dendritic cells and suppresses tumor growth.
Author:	Fushimi, Toshiaki\|O'Connor, Timothy P\|Crystal, Ronald G
PMID:	16585175

9.
Journal:	Tumour Biol. 2006;27(3):166-74.
Title:	Involvement of chemokine receptor CCR6 in colorectal cancer metastasis.
Author:	Rubie, Claudia\|Oliveira, Vilma\|Kempf, Katja\|Wagner, Mathias\|Tilton, Bettina\|Rau, Bettina\|Kruse, Bianca\|Konig, Jochen\|Schilling, Martin
PMID:	16641550

10.
Journal:	Clin Cancer Res. 2006 May 1;12(9):2795-803.
Title:	Overexpression of both CXC chemokine receptor 4 and vascular endothelial growth factor proteins predicts early distant relapse in stage II-III colorectal cancer patients.
Author:	Ottaiano, Alessandro\|Franco, Renato\|Aiello Talamanca, Annarita\|Liguori, Giuseppina\|Tatangelo, Fabiana\|Delrio, Paolo\|Nasti, Guglielmo\|Barletta, Emiddio\|Facchini, Gaetano\|Daniele, Bruno\|Di Blasi, Arturo\|Napolitano, Maria\|Ierano, Caterina\|Calemma, Rosa\|Leona
PMID:	16675573

11.
Journal:	Ann Surg. 2006 Jul;244(1):113-20.
Title:	Chemokine receptor CXCR4 expression in patients with melanoma and colorectal cancer liver metastases and the association with disease outcome.
Author:	Kim, Joseph\|Mori, Takuji\|Chen, Steven L\|Amersi, Farin F\|Martinez, Steve R\|Kuo, Christine\|Turner, Roderick R\|Ye, Xing\|Bilchik, Anton J\|Morton, Donald L\|Hoon, Dave S B
PMID:	16794396

12.
Journal:	Int J Cancer. 2006 Nov 1;119(9):2044-53.
Title:	Adenosine upregulates CXCR4 and enhances the proliferative and migratory responses of human carcinoma cells to CXCL12/SDF-1alpha.
Author:	Richard, Cynthia Lee\|Tan, Ernest Yoh\|Blay, Jonathan
PMID:	16823836

13.
Journal:	World J Gastroenterol. 2006 Nov 7;12(41):6627-33.
Title:	Chemokine expression in hepatocellular carcinoma versus colorectal liver metastases.
Author:	Rubie, Claudia\|Frick, Vilma Oliveira\|Wagner, Mathias\|Weber, Christina\|Kruse, Bianca\|Kempf, Katja\|Konig, Jochen\|Rau, Bettina\|Schilling, Martin
PMID:	17075975

14.
Journal:	Stem Cells. 2007 Feb;25(2):520-8.
Title:	Differential gene expression associated with migration of mesenchymal stem cells to conditioned medium from tumor cells or bone marrow cells.
Author:	Menon, Lata G\|Picinich, Sonia\|Koneru, Rajeth\|Gao, Hui\|Lin, Siang Yo\|Koneru, Mythili\|Mayer-Kuckuk, Philipp\|Glod, John\|Banerjee, Debabrata
PMID:	17053212

15.
Journal:	Oncogene. 2007 May 17;26(23):3329-37. Epub 2006 Nov 27.
Title:	Negative regulation of chemokine receptor CXCR4 by tumor suppressor p53 in breast cancer cells: implications of p53 mutation or isoform expression on breast cancer cell invasion.
Author:	Mehta, S A\|Christopherson, K W\|Bhat-Nakshatri, P\|Goulet, R J Jr\|Broxmeyer, H E\|Kopelovich, L\|Nakshatri, H
PMID:	17130833

16.
Journal:	Int J Mol Med. 2007 Jan;19(1):11-5.
Title:	Polymorphism and circulating levels of the chemokine CXCL12 in colorectal cancer patients.
Author:	Dimberg, Jan\|Hugander, Anders\|Lofgren, Sture\|Wagsater, Dick
PMID:	17143542

17.
Journal:	Cancer Detect Prev. 2007;31(4):282-95.
Title:	Identification of gene signatures for invasive colorectal tumor cells.
Author:	Wiese, Anja H\|Auer, Johannes\|Lassmann, Silke\|Nahrig, Jorg\|Rosenberg, Robert\|Hofler, Heinz\|Ruger, Rudiger\|Werner, Martin
PMID:	17936523

18.
Journal:	Oncol Rep. 2007 Dec;18(6):1583-7.
Title:	Analysis of CXCL12 3'UTR G>A polymorphism in colorectal cancer.
Author:	Hidalgo-Pascual, M\|Galan, J J\|Chaves-Conde, M\|Ramirez-Armengol, J A\|Moreno, C\|Calvo, E\|Pelaez, P\|Crespo, C\|Ruiz, A\|Royo, J L
PMID:	17982648

19.
Journal:	Virchows Arch. 2008 May;452(5):535-44.
Title:	Presence of HIF-1 and related genes in normal mucosa, adenomas and carcinomas of the colorectum.
Author:	Greijer, Astrid E\|Delis-van Diemen, Pien M\|Fijneman, Remond J A\|Giles, Rachel H\|Voest, Emile E\|van Hinsbergh, Victor W M\|Meijer, Gerrit A
PMID:	18351386

20.
Journal:	World J Gastroenterol. 2008 Apr 21;14(15):2308-13.
Title:	Inhibition of CXCR4 activity with AMD3100 decreases invasion of human colorectal cancer cells in vitro.
Author:	Li, Ji-Kun\|Yu, Liang\|Shen, Yun\|Zhou, Li-Sheng\|Wang, Yi-Cheng\|Zhang, Jian-Hai
PMID:	18416455

21.
Journal:	Nan Fang Yi Ke Da Xue Xue Bao. 2008 May;28(5):696-9.
Title:	[Role of vascular endothelial growth factor receptor 1-positive hematopoietic progenitor cell clusters in human colorectal carcinoma metastasis].
Author:	Yang, Zhao-hui\|Yang, Min\|Xiong, Han-zhen\|Li, Xue-nong
PMID:	18504182

22.
Journal:	Gastroenterology. 2008 Aug;135(2):508-17.
Title:	Constitutive CXCL12 expression induces anoikis in colorectal carcinoma cells.
Author:	Wendt, Michael K\|Drury, Luke J\|Vongsa, Rebecca A\|Dwinell, Michael B
PMID:	18558091

23.
Journal:	Eur J Cancer. 2008 Aug;44(12):1761-9.
Title:	Expression profiling of angiogenic genes for the characterisation of colorectal carcinoma.
Author:	Carrer, Alessandro\|Zacchigna, Serena\|Balani, Alessandro\|Pistan, Valentina\|Adami, Adelino\|Porcelli, Fabio\|Scaramucci, Monica\|Roseano, Mauro\|Turoldo, Angelo\|Prati, Maria Cristina\|Dell'Omodarme, Matteo\|de Manzini, Nicolo'\|Giacca, Mauro
PMID:	18656346

24.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2008 Sep;11(5):482-6.
Title:	[Expression of chemokine receptor CXCR4 in colorectal carcinoma and its relationship with clinicopathological parameters].
Author:	Yu, Liang\|Shen, Yun\|Li, Ji-Kun\|Sun, Yu-Hao\|Wang, Yi-Cheng\|Zhang, Jian-Hai
PMID:	18803056

25.
Journal:	Cancer Immunol Immunother. 2009 Jan;58(1):85-94.
Title:	Expression and function of T cell homing molecules in Hodgkin's lymphoma.
Author:	Machado, Lee\|Jarrett, Ruth\|Morgan, Susan\|Murray, Paul\|Hunter, Beatrix\|Hamilton, Emma\|Crocker, John\|Thomas, Wendy\|Steven, Neil\|Ismail, Tariq\|Chapman, Ann\|Adams, David H\|Lee, Steven P
PMID:	18488221

26.
Journal:	Cell Cycle. 2009 Apr 15;8(8):1228-37. Epub 2009 Apr 23.
Title:	A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration.
Author:	Ierano, Caterina\|Giuliano, Paola\|D'Alterio, Crescenzo\|Cioffi, Michele\|Mettivier, Valentina\|Portella, Luigi\|Napolitano, Maria\|Barbieri, Antonio\|Arra, Claudio\|Liguori, Giuseppina\|Franco, Renato\|Palmieri, Giuseppe\|Rozzo, Carla\|Pacelli, Roberto\|Castello, Gius
PMID:	19305148

27.
Journal:	Zhonghua Wai Ke Za Zhi. 2009 Feb 1;47(3):210-3.
Title:	[Effect of stromal cell-derived factor-1 and its receptor CXCR4 on liver metastasis of human colon cancer].
Author:	Ding, Yin-Lu\|Fu, Qin-Ye\|Tang, Si-Feng\|Zhang, Jian-Liang\|Li, Zhan-Yuan\|Li, Zhao-Ting
PMID:	19563077

28.
Journal:	Neoplasia. 2009 Jul;11(7):651-61.
Title:	CXCR4 regulates the early extravasation of metastatic tumor cells in vivo.
Author:	Gassmann, Peter\|Haier, Jorg\|Schluter, Kerstin\|Domikowsky, Britta\|Wendel, Claudia\|Wiesner, Ulrike\|Kubitza, Robert\|Engers, Rainer\|Schneider, Stephan W\|Homey, Bernhard\|Muller, Anja
PMID:	19568410

29.
Journal:	Ann Surg Oncol. 2009 Sep;16(9):2645-53.
Title:	Hepatic stellate cells promote liver metastasis of colon cancer cells by the action of SDF-1/CXCR4 axis.
Author:	Matsusue, Ryo\|Kubo, Hajime\|Hisamori, Shigeo\|Okoshi, Kae\|Takagi, Hidekazu\|Hida, Koya\|Nakano, Keiko\|Itami, Atsushi\|Kawada, Kenji\|Nagayama, Satoshi\|Sakai, Yoshiharu
PMID:	19588204

30.
Journal:	Am J Clin Pathol. 2009 Aug;132(2):202-10; quiz 307.
Title:	Prognostic significance of CXCL12 expression in patients with colorectal carcinoma.
Author:	Akishima-Fukasawa, Yuri\|Nakanishi, Yukihiro\|Ino, Yoshinori\|Moriya, Yoshihiro\|Kanai, Yae\|Hirohashi, Setsuo
PMID:	19605814

31.
Journal:	Cancer Biol Ther. 2009 Sep;8(17):1608-14. Epub 2009 Sep 6.
Title:	CXCL12, CXCR4 and CXCR7 expression in brain metastases.
Author:	Salmaggi, Andrea\|Maderna, Emanuela\|Calatozzolo, Chiara\|Gaviani, Paola\|Canazza, Alessandra\|Milanesi, Ida\|Silvani, Antonio\|DiMeco, Francesco\|Carbone, Antonino\|Pollo, Bianca
PMID:	19625779

32.
Journal:	Histopathology. 2009 Nov;55(5):576-86.
Title:	The role of vascular CXCR4 expression in colorectal carcinoma.
Author:	Ingold, Barbara\|Schulz, Stefan\|Budczies, Jan\|Neumann, Ulf\|Ebert, Matthias P A\|Weichert, Wilko\|Rocken, Christoph
PMID:	19912363

33.
Journal:	Zhonghua Wei Chang Wai Ke Za Zhi. 2009 Nov;12(6):627-9.
Title:	[Shikonin down-regulates CXCR4 expression and inhibits CXCL12-induced migratory responses in colorectal carcinoma cell line SW480].
Author:	Wen, Zhuo-fu\|Wei, Xiu-qing\|Guo, Yun-wei\|Zheng, Feng-ping
PMID:	19921580

34.
Journal:	Int J Cancer. 2010 Mar 15;126(6):1302-15.
Title:	CXCR4 and CXCR7 regulate angiogenesis and CT26.WT tumor growth independent from SDF-1.
Author:	Kollmar, Otto\|Rupertus, Kathrin\|Scheuer, Claudia\|Nickels, Ruth M\|Haberl, Gudrun C Y\|Tilton, Bettina\|Menger, Michael D\|Schilling, Martin K
PMID:	19821487

35.
Journal:	BMC Mol Biol. 2010 Feb 1;11:12.
Title:	Identification of endogenous control genes for normalisation of real-time quantitative PCR data in colorectal cancer.
Author:	Kheirelseid, Elrasheid A H\|Chang, Kah Hoong\|Newell, John\|Kerin, Michael J\|Miller, Nicola
PMID:	20122155

36.
Journal:	Ann Surg Oncol. 2010 Aug;17(8):2051-8.
Title:	Stromal CXCR4 and CXCL12 expression is associated with distant recurrence and poor prognosis in rectal cancer after chemoradiotherapy.
Author:	Saigusa, Susumu\|Toiyama, Yuji\|Tanaka, Koji\|Yokoe, Takeshi\|Okugawa, Yoshinaga\|Kawamoto, Aya\|Yasuda, Hiromi\|Inoue, Yasuhiro\|Miki, Chikao\|Kusunoki, Masato
PMID:	20177796

37.
Journal:	Hum Pathol. 2010 Jul;41(7):990-1001.
Title:	Expression of angiostatic platelet factor-4var/CXCL4L1 counterbalances angiogenic impulses of vascular endothelial growth factor, interleukin-8/CXCL8, and stromal cell-derived factor 1/CXCL12 in esophageal and colorectal cancer.
Author:	Verbeke, Hannelien\|De Hertogh, Gert\|Li, Sandra\|Vandercappellen, Jo\|Noppen, Samuel\|Schutyser, Evemie\|El-Asrar, Ahmed Abu\|Opdenakker, Ghislain\|Van Damme, Jo\|Geboes, Karel\|Struyf, Sofie
PMID:	20334899

38.
Journal:	J Mol Med (Berl). 2010 Dec;88(12):1243-53.
Title:	Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor.
Author:	Yadav, Vivek R\|Sung, Bokyung\|Prasad, Sahdeo\|Kannappan, Ramaswamy\|Cho, Sung-Gook\|Liu, Mingyao\|Chaturvedi, Madan M\|Aggarwal, Bharat B
PMID:	20798912

39.
Journal:	PLoS One. 2010 Sep 22;5(9):e12895.
Title:	CXCL12 chemokine expression and secretion regulates colorectal carcinoma cell anoikis through Bim-mediated intrinsic apoptosis.
Author:	Drury, Luke J\|Wendt, Michael K\|Dwinell, Michael B
PMID:	20877573

40.
Journal:	Mol Cancer. 2010 Oct 14;9:273.
Title:	Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12.
Author:	Rigo, Antonella\|Gottardi, Michele\|Zamo, Alberto\|Mauri, Pierluigi\|Bonifacio, Massimiliano\|Krampera, Mauro\|Damiani, Ernesto\|Pizzolo, Giovanni\|Vinante, Fabrizio
PMID:	20946648

41.
Journal:	Tumour Biol. 2011 Feb;32(1):189-96.
Title:	Changes in CXCL12/CXCR4-chemokine expression during onset of colorectal malignancies.
Author:	Oliveira Frick, Vilma\|Rubie, Claudia\|Ghadjar, Pirus\|Faust, Sabrina K\|Wagner, Mathias\|Graber, Stefan\|Schilling, Martin K
PMID:	20865359

42.
Journal:	Int J Oncol. 2011 Mar;38(3):655-63.
Title:	Cancer-associated fibroblasts correlate with poor prognosis in rectal cancer after chemoradiotherapy.
Author:	Saigusa, Susumu\|Toiyama, Yuji\|Tanaka, Koji\|Yokoe, Takeshi\|Okugawa, Yoshinaga\|Fujikawa, Hiroyuki\|Matsusita, Kohei\|Kawamura, Mikio\|Inoue, Yasuhiro\|Miki, Chikao\|Kusunoki, Masato
PMID:	21240461

43.
Journal:	J Transl Med. 2011 Feb 24;9:22.
Title:	CXC receptor-4 mRNA silencing abrogates CXCL12-induced migration of colorectal cancer cells.
Author:	Rubie, Claudia\|Frick, Vilma O\|Ghadjar, Pirus\|Wagner, Mathias\|Justinger, Christoph\|Faust, Sabrina K\|Vicinus, Benjamin\|Graber, Stefan\|Kollmar, Otto\|Schilling, Martin K
PMID:	21349176

44.
Journal:	World J Gastroenterol. 2011 Feb 7;17(5):625-32.
Title:	Influence of CXCR4/SDF-1 axis on E-cadherin/beta-catenin complex expression in HT29 colon cancer cells.
Author:	Wang, Lin\|Li, Cui-Ling\|Wang, Lei\|Yu, Wen-Bin\|Yin, Hai-Peng\|Zhang, Guang-Yong\|Zhang, Li-Feng\|Li, Sheng\|Hu, San-Yuan
PMID:	21350711

45.
Journal:	Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):17655-60.
Title:	Monomeric and dimeric CXCL12 inhibit metastasis through distinct CXCR4 interactions and signaling pathways.
Author:	Drury, Luke J\|Ziarek, Joshua J\|Gravel, Stephanie\|Veldkamp, Christopher T\|Takekoshi, Tomonori\|Hwang, Samuel T\|Heveker, Nikolaus\|Volkman, Brian F\|Dwinell, Michael B
PMID:	21990345

46.
Journal:	Histopathology. 2011 Sep;59(3):470-81.
Title:	Histopathological predictors of regional lymph node metastasis at the invasive front in early colorectal cancer.
Author:	Akishima-Fukasawa, Yuri\|Ishikawa, Yukio\|Akasaka, Yoshikiyo\|Uzuki, Miwa\|Inomata, Naomi\|Yokoo, Tomoko\|Ishii, Ryuga\|Shimokawa, Reiko\|Mukai, Kiyoshi\|Kiguchi, Hideko\|Suzuki, Koyu\|Fujiwara, Mieko\|Ogata, Kentaro\|Niino, Hitoshi\|Sugiura, Hitoshi\|Ichinose, Akihiro\|
PMID:	22034887

47.
Journal:	Int J Stem Cells. 2011 Jun;4(1):70-5.
Title:	Human Embryonic-like ECM (hECM) Stimulates Proliferation and Differentiation in Stem Cells While Killing Cancer Cells.
Author:	Pinney, Emmett\|Zimber, Michael\|Schenone, Aaron\|Montes-Camacho, Mayra\|Ziegler, Frank\|Naughton, Gail K
PMID:	24298336

48.
Journal:	Invest New Drugs. 2012 Apr;30(2):508-17.
Title:	Modulating the interaction of CXCR4 and CXCL12 by low-molecular-weight heparin inhibits hepatic metastasis of colon cancer.
Author:	Ma, Lixin\|Qiao, Haiquan\|He, Changjun\|Yang, Qian\|Cheung, Chun Hei Antonio\|Kanwar, Jagat R\|Sun, Xueying
PMID:	21080209

49.
Journal:	J Cell Physiol. 2012 Mar;227(3):1114-22.
Title:	Stromal cell-derived factor-1/CXC receptor 4 and beta1 integrin interaction regulates urokinase-type plasminogen activator expression in human colorectal cancer cells.
Author:	Huang, Wen-Shih\|Chin, Chih-Chien\|Chen, Cheng-Nan\|Kuo, Yi-Hung\|Chen, Te-Chuan\|Yu, Hong-Ren\|Tung, Shui-Yi\|Shen, Chien-Heng\|Hsieh, Yung-Yu\|Guo, Su-Er\|Shi, Chung-Sheng\|Liu, Ta-Ju\|Kuo, Hsing-Chun
PMID:	21567400

50.
Journal:	Ann Surg Oncol. 2012 Jul;19 Suppl 3:S339-46.
Title:	CXCR4 expression predicts patient outcome and recurrence patterns after hepatic resection for colorectal liver metastases.
Author:	Yopp, Adam C\|Shia, Jinru\|Butte, Jean M\|Allen, Peter J\|Fong, Yuman\|Jarnagin, William R\|DeMatteo, Ronald P\|D'Angelica, Michael I
PMID:	21584832

51.
Journal:	J Oncol. 2012;2012:196957.
Title:	Bone Marrow Suppression by c-Kit Blockade Enhances Tumor Growth of Colorectal Metastases through the Action of Stromal Cell-Derived Factor-1.
Author:	Rupertus, Kathrin\|Haberl, Gudrun C Y\|Scheuer, Claudia\|Menger, Michael D\|Schilling, Martin K\|Kollmar, Otto
PMID:	21977032

52.
Journal:	Clin Exp Metastasis. 2012 Feb;29(2):101-10.
Title:	CXCR4/CXCL12 expression profile is associated with tumor microenvironment and clinical outcome of liver metastases of colorectal cancer.
Author:	Sakai, Nozomu\|Yoshidome, Hiroyuki\|Shida, Takashi\|Kimura, Fumio\|Shimizu, Hiroaki\|Ohtsuka, Masayuki\|Takeuchi, Dan\|Sakakibara, Masahiro\|Miyazaki, Masaru
PMID:	22075627

53.
Journal:	Curr Mol Med. 2012 Feb;12(2):153-62.
Title:	Xanthohumol, a prenylated chalcone derived from hops, suppresses cancer cell invasion through inhibiting the expression of CXCR4 chemokine receptor.
Author:	Wang, Y\|Chen, Y\|Wang, J\|Chen, J\|Aggarwal, B B\|Pang, X\|Liu, M
PMID:	22172099

54.
Journal:	J Korean Soc Coloproctol. 2012 Feb;28(1):3-4.
Title:	Will the Stroma-derived Factor-1alpha (CXCL12)/CXCR4 Pathway Become a Major Concern for Advanced Colorectal Cancer?
Author:	Kim, Hungdai
PMID:	22413073

55.
Journal:	Immunity. 2012 May 25;36(5):742-54.
Title:	NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-kappaB signaling.
Author:	Allen, Irving C\|Wilson, Justin E\|Schneider, Monika\|Lich, John D\|Roberts, Reid A\|Arthur, Janelle C\|Woodford, Rita-Marie T\|Davis, Beckley K\|Uronis, Joshua M\|Herfarth, Hans H\|Jobin, Christian\|Rogers, Arlin B\|Ting, Jenny P-Y
PMID:	22503542

56.
Journal:	Mol Cancer Ther. 2012 Nov;11(11):2516-25.
Title:	A locked, dimeric CXCL12 variant effectively inhibits pulmonary metastasis of CXCR4-expressing melanoma cells due to enhanced serum stability.
Author:	Takekoshi, Tomonori\|Ziarek, Joshua J\|Volkman, Brian F\|Hwang, Sam T
PMID:	22869557

57.
Journal:	BMC Med. 2012 Aug 7;10:85.
Title:	CD133(+)CXCR4(+) colon cancer cells exhibit metastatic potential and predict poor prognosis of patients.
Author:	Zhang, Shan-shan\|Han, Zhi-peng\|Jing, Ying-ying\|Tao, Shuang-fen\|Li, Tie-jun\|Wang, Hao\|Wang, Yang\|Li, Rong\|Yang, Yang\|Zhao, Xue\|Xu, Xiao-dong\|Yu, En-da\|Rui, Yao-cheng\|Liu, Hou-jia\|Zhang, Li\|Wei, Li-xin
PMID:	22871210

58.
Journal:	Int J Mol Med. 2012 Dec;30(6):1537-43.
Title:	Stromal cell-derived factor-1alpha and macrophage migration-inhibitory factor induce metastatic behavior in CXCR4-expressing colon cancer cells.
Author:	Shin, Han-Na\|Moon, Hyun-Hye\|Ku, Ja-Lok
PMID:	23023114

59.
Journal:	J Biomed Sci. 2012 Oct 25;19:91.
Title:	CXC chemokine ligand 12/stromal cell-derived factor-1 regulates cell adhesion in human colon cancer cells by induction of intercellular adhesion molecule-1.
Author:	Tung, Shui-Yi\|Chang, Shun-Fu\|Chou, Ming-Hui\|Huang, Wen-Shih\|Hsieh, Yung-Yu\|Shen, Chien-Heng\|Kuo, Hsing-Chun\|Chen, Cheng-Nan
PMID:	23098564

60.
Journal:	J Cell Physiol. 2013 May;228(5):1017-24.
Title:	Visfatin induces stromal cell-derived factor-1 expression by beta1 integrin signaling in colorectal cancer cells.
Author:	Huang, Wen-Shih\|Chen, Cheng-Nan\|Sze, Chun-I\|Teng, Chih-Chuan
PMID:	23042611

61.
Journal:	Cancer Biol Ther. 2013 Feb;14(2):175-83.
Title:	Histone deacetylase inhibitors induce CXCR4 mRNA but antagonize CXCR4 migration.
Author:	Ierano, Caterina\|Basseville, Agnes\|To, Kenneth K W\|Zhan, Zhirong\|Robey, Robert W\|Wilkerson, Julia\|Bates, Susan E\|Scala, Stefania
PMID:	23192271

62.
Journal:	Indian J Gastroenterol. 2013 Jan;32(1):28-31.
Title:	SDF-1alpha G801A polymorphism in Southern Iranian patients with colorectal and gastric cancers.
Author:	Razmkhah, Mahboobeh\|Ghaderi, Abbas
PMID:	23242967

63.
Journal:	J Gastrointest Oncol. 2013 Jun;4(2):144-57.
Title:	Clinical applications of gene expression in colorectal cancer.
Author:	Kheirelseid, Elrasheid A H\|Miller, Nicola\|Chang, Kah Hoong\|Nugent, Mary\|Kerin, Michael J
PMID:	23730510

64.
Journal:	Arch Med Sci. 2013 Dec 30;9(6):999-1005.
Title:	CXCL12-G801A polymorphism modulates risk of colorectal cancer in Taiwan.
Author:	Shi, Ming-Der\|Chen, Jing-Hsien\|Sung, Hsin-Te\|Lee, Jung-Shin\|Tsai, Li-Yu\|Lin, Hui-Hsuan
PMID:	24482642

65.
Journal:	Carcinogenesis. 2014 Feb;35(2):282-91.
Title:	SDF-1/CXCR4 axis promotes directional migration of colorectal cancer cells through upregulation of integrin alphavbeta6.
Author:	Wang, Ben\|Wang, Wenke\|Niu, Weibo\|Liu, Enyu\|Liu, Xiangjuan\|Wang, Jiayong\|Peng, Cheng\|Liu, Song\|Xu, Ling\|Wang, Lei\|Niu, Jun
PMID:	24085800

66.
Journal:	Clin Cancer Res. 2014 Feb 1;20(3):604-16.
Title:	The disparate twins: a comparative study of CXCR4 and CXCR7 in SDF-1alpha-induced gene expression, invasion and chemosensitivity of colon cancer.
Author:	Heckmann, Doreen\|Maier, Patrick\|Laufs, Stephanie\|Li, Li\|Sleeman, Jonathan P\|Trunk, Marcus J\|Leupold, Jorg H\|Wenz, Frederik\|Zeller, W Jens\|Fruehauf, Stefan\|Allgayer, Heike
PMID:	24255072

67.
Journal:	Int J Cancer. 2014 Jul 15;135(2):379-90.
Title:	A prognostic model comprising pT stage, N status, and the chemokine receptors CXCR4 and CXCR7 powerfully predicts outcome in neoadjuvant resistant rectal cancer patients.
Author:	D'Alterio, Crescenzo\|Avallone, Antonio\|Tatangelo, Fabiana\|Delrio, Paolo\|Pecori, Biagio\|Cella, Laura\|Pelella, Alessia\|D'Armiento, Francesco Paolo\|Carlomagno, Chiara\|Bianco, Franco\|Silvestro, Lucrezia\|Pacelli, Roberto\|Napolitano, Maria\|Iaffaioli, Rosario Vi
PMID:	24375277

68.
Journal:	Clin Exp Metastasis. 2014 Apr;31(4):447-59.
Title:	Interaction of the chemokines I-TAC (CXCL11) and SDF-1 (CXCL12) in the regulation of tumor angiogenesis of colorectal cancer.
Author:	Rupertus, Kathrin\|Sinistra, Janine\|Scheuer, Claudia\|Nickels, Ruth M\|Schilling, Martin K\|Menger, Michael D\|Kollmar, Otto
PMID:	24493023

69.
Journal:	Ann Surg Oncol. 2014 Jun;21(6):1809-16.
Title:	Combined morphologic and molecular classification for predicting lymph node metastasis in early-stage colorectal adenocarcinoma.
Author:	Ryu, Han Suk\|Kim, Woo Ho\|Ahn, Soyeon\|Kim, Duck-Woo\|Kang, Sung-Bum\|Park, Hyo Jin\|Park, Young Soo\|Lee, Chung Hun\|Lee, Hye Seung
PMID:	24562932

70.
Journal:	Mol Cancer. 2014 Mar 14;13:58.
Title:	Hypoxia differentially regulated CXCR4 and CXCR7 signaling in colon cancer.
Author:	Romain, Benoit\|Hachet-Haas, Muriel\|Rohr, Serge\|Brigand, Cecile\|Galzi, Jean-Luc\|Gaub, Marie-Pierre\|Pencreach, Erwan\|Guenot, Dominique
PMID:	24629239

71.
Journal:	Br J Surg. 2014 Sep;101(10):1299-309.
Title:	Biomarker-based treatment selection in early-stage rectal cancer to promote organ preservation.
Author:	Leong, K J\|Beggs, A\|James, J\|Morton, D G\|Matthews, G M\|Bach, S P
PMID:	25052224

72.
Journal:	Cancer Lett. 2014 Nov 28;354(2):417-26.
Title:	SDF-1/CXCR4 promotes epithelial-mesenchymal transition and progression of colorectal cancer by activation of the Wnt/beta-catenin signaling pathway.
Author:	Hu, Ting-Hua\|Yao, Yu\|Yu, Shuo\|Han, Li-Li\|Wang, Wen-Juan\|Guo, Hui\|Tian, Tao\|Ruan, Zhi-Pin\|Kang, Xiao-Min\|Wang, Jing\|Wang, Shu-Hong\|Nan, Ke-Jun
PMID:	25150783

73.
Journal:	Cancers (Basel). 2014 Aug 29;6(3):1753-68.
Title:	Circulating biomarkers in advanced colorectal cancer patients randomly assigned to three bevacizumab-based regimens.
Author:	Martinetti, Antonia\|Miceli, Rosalba\|Sottotetti, Elisa\|Di Bartolomeo, Maria\|de Braud, Filippo\|Gevorgyan, Arpine\|Dotti, Katia Fiorella\|Bajetta, Emilio\|Campiglio, Manuela\|Bianchi, Francesca\|Bregni, Giacomo\|Pietrantonio, Filippo
PMID:	25256831

74.
Journal:	PLoS One. 2014 Nov 18;9(11):e113513.
Title:	Examining the polymorphisms in the hypoxia pathway genes in relation to outcome in colorectal cancer.
Author:	Haja Mohideen, Asan M S\|Hyde, Angela\|Squires, Jessica\|Wang, Jing\|Dicks, Elizabeth\|Younghusband, Ban\|Parfrey, Patrick\|Green, Roger\|Savas, Sevtap
PMID:	25405996

75.
Journal:	J Immunoassay Immunochem. 2015;36(2):182-94.
Title:	Relationship between SDF-1G801A polymorphism and its expression in Tunisian patients with colorectal cancer.
Author:	Amara, Sameh\|Chaar, Ines\|Khiari, Meriem\|Ounissi, Donia\|Hmida, Abdelmajid B\|Mzabi, Sabeh Regaya\|Bouraoui, Saadia
PMID:	24825098

76.
Journal:	Hepatology. 2015 Jan;61(1):238-48.
Title:	Tissue inhibitor of metalloproteinases (TIMP)-1 creates a premetastatic niche in the liver through SDF-1/CXCR4-dependent neutrophil recruitment in mice.
Author:	Seubert, Bastian\|Grunwald, Barbara\|Kobuch, Julia\|Cui, Haissi\|Schelter, Florian\|Schaten, Susanne\|Siveke, Jens T\|Lim, Ngee H\|Nagase, Hideaki\|Simonavicius, Nicole\|Heikenwalder, Mathias\|Reinheckel, Thomas\|Sleeman, Jonathan P\|Janssen, Klaus-Peter\|Knolle, Percy
PMID:	25131778

77.
Journal:	Mol Cancer Ther. 2015 Feb;14(2):480-90.
Title:	Identification of LY2510924, a novel cyclic peptide CXCR4 antagonist that exhibits antitumor activities in solid tumor and breast cancer metastatic models.
Author:	Peng, Sheng-Bin\|Zhang, Xiaoyi\|Paul, Donald\|Kays, Lisa M\|Gough, Wendy\|Stewart, Julie\|Uhlik, Mark T\|Chen, Qi\|Hui, Yu-Hua\|Zamek-Gliszczynski, Maciej J\|Wijsman, John A\|Credille, Kelly M\|Yan, Liang Zeng
PMID:	25504752

78.
Journal:	Curr Pharm Des. 2015;21(17):2276-83.
Title:	CXCR4 and CXCL12 Expression in Rectal Tumors of Stage IV Patients Before and After Local Radiotherapy and Systemic Neoadjuvant Treatment.
Author:	Tamas, Karin\|Domanska, Urszula M\|van Dijk, Tonnis H\|Timmer-Bosscha, Hetty\|Havenga, Klaas\|Karrenbeld, Arend\|Sluiter, Wim J\|Beukema, Jannet C\|van Vugt, Marcel A T M\|de Vries, Elisabeth G E\|Hospers, Geke A P\|Walenkamp, Annemiek M E
PMID:	25557636

79.
Journal:	Biomed Pharmacother. 2015 Apr;71:46-52.
Title:	Downregulation of the CXCR4/CXCL12 axis blocks the activation of the Wnt/beta-catenin pathway in human colon cancer cells.
Author:	Song, Zhi-Yu\|Gao, Zu-Hua\|Chu, Jia-Hui\|Han, Xiu-Zhen\|Qu, Xian-Jun
PMID:	25960214

80.
Journal:	FASEB J. 2015 Aug;29(8):3571-81.
Title:	The critical roles of tumor-initiating cells and the lymph node stromal microenvironment in human colorectal cancer extranodal metastasis using a unique humanized orthotopic mouse model.
Author:	Margolin, David A\|Myers, Tamara\|Zhang, Xin\|Bertoni, Danielle M\|Reuter, Brian A\|Obokhare, Izi\|Borgovan, Theodor\|Grimes, Chelsea\|Green, Heather\|Driscoll, Tiffany\|Lee, Chung-Gi\|Davis, Nancy K\|Li, Li
PMID:	25962655

81.
Journal:	Sci Rep. 2015 May 28;5:10357.
Title:	Identification of a distinct population of CD133(+)CXCR4(+) cancer stem cells in ovarian cancer.
Author:	Cioffi, Michele\|D'Alterio, Crescenzo\|Camerlingo, Rosalba\|Tirino, Virginia\|Consales, Claudia\|Riccio, Anna\|Ierano, Caterina\|Cecere, Sabrina Chiara\|Losito, Nunzia Simona\|Greggi, Stefano\|Pignata, Sandro\|Pirozzi, Giuseppe\|Scala, Stefania
PMID:	26020117

82.
Journal:	Biomed Res Int. 2015;2015:326981.
Title:	Role of B7-H4 siRNA in Proliferation, Migration, and Invasion of LOVO Colorectal Carcinoma Cell Line.
Author:	Peng, Hai-Xia\|Wu, Wei-Qi\|Yang, Da-Ming\|Jing, Rong\|Li, Ji\|Zhou, Feng-Li\|Jin, Yun-Fei\|Wang, Sai-Yu\|Chu, Yi-Min
PMID:	26078947

83.
Journal:	Pathologe. 2015 Nov;36 Suppl 2:185-8.
Title:	[The metastatic niche. Mechanisms and prognostic implications].
Author:	Muders, M H\|Baretton, G B
PMID:	26395891

84.
Journal:	Cancer Biomark. 2015;15(6):869-79.
Title:	Stromal cell derived factor-1 and CXCR4 expression in colorectal cancer promote liver metastasis.
Author:	Amara, Sameh\|Chaar, Ines\|Khiari, Meriem\|Ounissi, Donia\|Weslati, Marwa\|Boughriba, Rahma\|Hmida, Abdelmajid B\|Bouraoui, Saadia
PMID:	26406413

85.
Journal:	BMC Cancer. 2015 Nov 10;15:882.
Title:	Chemotherapeutic agents attenuate CXCL12-mediated migration of colon cancer cells by selecting for CXCR4-negative cells and increasing peptidase CD26.
Author:	Cutler, Murray J\|Lowthers, Erica L\|Richard, Cynthia L\|Hajducek, Dagmar M\|Spagnuolo, Paul A\|Blay, Jonathan
PMID:	26552750

86.
Journal:	Int J Colorectal Dis. 2016 Jun;31(6):1225-6.
Title:	Functional diversity of stromal cell-derived factor 1 splice variants in colorectal cancer and melanoma.
Author:	Wehler, Thomas C\|Martchenko, Ksenia\|Allami, Risala H\|Becker, Marc\|Wehler, Beatrice\|Berger, Martin R\|Bals, Robert\|Galle, Peter R\|Theobald, Matthias\|Graf, Claudine\|Schimanski, Carl C
PMID:	26567118

87.
Journal:	Oncol Rep. 2016 Feb;35(2):676-82.
Title:	The dipeptidyl peptidase-4 inhibitor sitagliptin suppresses mouse colon tumorigenesis in type 2 diabetic mice.
Author:	Yorifuji, Naoki\|Inoue, Takuya\|Iguchi, Munetaka\|Fujiwara, Kaori\|Kakimoto, Kazuki\|Nouda, Sadaharu\|Okada, Toshihiko\|Kawakami, Ken\|Abe, Yosuke\|Takeuchi, Toshihisa\|Higuchi, Kazuhide
PMID:	26573958

88.
Journal:	Tumour Biol. 2016 Jun;37(6):7441-52.
Title:	CXCR4, CXCL12 and the relative CXCL12-CXCR4 expression as prognostic factors in colon cancer.
Author:	Stanisavljevic, Luka\|Assmus, Jorg\|Storli, Kristian Eeg\|Leh, Sabine Maria\|Dahl, Olav\|Myklebust, Mette Pernille
PMID:	26678887

89.
Journal:	Ann Surg Oncol. 2016 May;23(5):1601-8.
Title:	Angiogenesis-Related Markers and Prognosis After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy for Metastatic Colorectal Cancer.
Author:	de Cuba, E M V\|de Hingh, I H J T\|Sluiter, N R\|Kwakman, R\|Coupe, V M H\|Belien, J A M\|Verwaal, V J\|Meijerink, W J H J\|Delis-van Diemen, P M\|Bonjer, H J\|Meijer, G A\|Te Velde, E A
PMID:	26727921

90.
Journal:	Cancer Res. 2016 Jan 15;76(2):347-57.
Title:	Peritoneal Dissemination Requires an Sp1-Dependent CXCR4/CXCL12 Signaling Axis and Extracellular Matrix-Directed Spheroid Formation.
Author:	Kasagi, Yuta\|Harada, Yui\|Morodomi, Yosuke\|Iwai, Toshiki\|Saito, Satoru\|Yoshida, Kumi\|Oki, Eiji\|Saeki, Hiroshi\|Ohgaki, Kippei\|Sugiyama, Masahiko\|Onimaru, Mitsuho\|Maehara, Yoshihiko\|Yonemitsu, Yoshikazu
PMID:	26744523

91.
Journal:	Oncotarget. 2016 Apr 19;7(16):22174-85.
Title:	Modulation of chemokines in the tumor microenvironment enhances oncolytic virotherapy for colorectal cancer.
Author:	Francis, Lily\|Guo, Zong Sheng\|Liu, Zuqiang\|Ravindranathan, Roshni\|Urban, Julie A\|Sathaiah, Magesh\|Magge, Deepa\|Kalinski, Pawel\|Bartlett, David L
PMID:	26956047

92.
Journal:	Oncol Lett. 2016 Mar;11(3):1873-1878.
Title:	Analysis of the expression of SDF-1 splicing variants in human colorectal cancer and normal mucosa tissues.
Author:	Allami, Risala Hussain\|Graf, Claudine\|Martchenko, Ksenia\|Voss, Beatrice\|Becker, Marc\|Berger, Martin R\|Galle, Peter R\|Theobald, Matthias\|Wehler, Thomas C\|Schimanski, Carl C
PMID:	26998092

93.
Journal:	Nanomedicine. 2016 Oct;12(7):1987-1996.
Title:	Cancer-specific uptake of a liganded protein nanocarrier targeting aggressive CXCR4(+) colorectal cancer models.
Author:	Cespedes, Maria Virtudes\|Unzueta, Ugutz\|Alamo, Patricia\|Gallardo, Alberto\|Sala, Rita\|Casanova, Isolda\|Pavon, Miguel Angel\|Mangues, Maria Antonia\|Trias, Manuel\|Lopez-Pousa, Antonio\|Villaverde, Antonio\|Vazquez, Esther\|Mangues, Ramon
PMID:	27085904

94.
Journal:	J Med Chem. 2016 Sep 22;59(18):8369-80.
Title:	Exploring the N-Terminal Region of C-X-C Motif Chemokine 12 (CXCL12): Identification of Plasma-Stable Cyclic Peptides As Novel, Potent C-X-C Chemokine Receptor Type 4 (CXCR4) Antagonists.
Author:	Di Maro, Salvatore\|Trotta, Anna Maria\|Brancaccio, Diego\|Di Leva, Francesco Saverio\|La Pietra, Valeria\|Ierano, Caterina\|Napolitano, Maria\|Portella, Luigi\|D'Alterio, Crescenzo\|Siciliano, Rosa Anna\|Sementa, Deborah\|Tomassi, Stefano\|Carotenuto, Alfonso\|Novell
PMID:	27571038

95.
Journal:	Med Oncol. 2016 Oct;33(10):111.
Title:	Identification of key pathways and genes in colorectal cancer using bioinformatics analysis.
Author:	Liang, Bin\|Li, Chunning\|Zhao, Jianying
PMID:	27581154

96.
Journal:	Oncol Rep. 2016 Dec;36(6):3635-3642.
Title:	Effect of colorectal cancer on the number of normal stem cells circulating in peripheral blood.
Author:	Marlicz, Wojciech\|Sielatycka, Katarzyna\|Serwin, Karol\|Kubis, Ewa\|Tkacz, Marta\|Gluszko, Rafal\|Bialek, Andrzej\|Starzynska, Teresa\|Ratajczak, Mariusz Z
PMID:	27779706

97.
Journal:	Oncoimmunology. 2016 Nov 29;5(12):e1254313.
Title:	CXCR4-CXCL12-CXCR7, TLR2-TLR4, and PD-1/PD-L1 in colorectal cancer liver metastases from neoadjuvant-treated patients.
Author:	D'Alterio, Crescenzo\|Nasti, Guglielmo\|Polimeno, Marianeve\|Ottaiano, Alessandro\|Conson, Manuel\|Circelli, Luisa\|Botti, Giovanni\|Scognamiglio, Giosue\|Santagata, Sara\|De Divitiis, Chiara\|Nappi, Anna\|Napolitano, Maria\|Tatangelo, Fabiana\|Pacelli, Roberto\|Izzo,
PMID:	28123896

98.
Journal:	Cell Adh Migr. 2017 Jan 2;11(1):13-23.
Title:	LPS-induced CXCR4-dependent migratory properties and a mesenchymal-like phenotype of colorectal cancer cells.
Author:	Liu, Wen-Ting\|Jing, Ying-Ying\|Yan, Fei\|Han, Zhi-Peng\|Lai, Fo-Bao\|Zeng, Jian-Xing\|Yu, Guo-Feng\|Fan, Qing-Min\|Li, Rong\|Zhao, Qiu-Dong\|Wu, Meng-Chao\|Wei, Li-Xin
PMID:	26745593

99.
Journal:	Integr Cancer Ther. 2017 Jun;16(2):244-251.
Title:	Onbaekwon Suppresses Colon Cancer Cell Invasion by Inhibiting Expression of the CXC Chemokine Receptor 4.
Author:	Kim, Buyun\|Yoon, Jaewoo\|Yoon, Seong Woo\|Park, Byoungduck
PMID:	27160279

100.
Journal:	Clin Cancer Res. 2017 Jan 15;23(2):549-561.
Title:	ADAM17 is a Tumor Promoter and Therapeutic Target in Western Diet-associated Colon Cancer.
Author:	Mustafi, Reba\|Dougherty, Urszula\|Mustafi, Devkumar\|Ayaloglu-Butun, Fatma\|Fletcher, Michelle\|Adhikari, Sarbani\|Sadiq, Farhana\|Meckel, Katherine\|Haider, Haider I\|Khalil, Abdurahman\|Pekow, Joel\|Konda, Vani\|Joseph, Loren\|Hart, John\|Fichera, Alessandro\|Li, Yan
PMID:	27489286

101.
Journal:	Exp Biol Med (Maywood). 2017 Feb;242(4):429-435.
Title:	Activation of CXCL12/CXCR4 renders colorectal cancer cells less sensitive to radiotherapy via up-regulating the expression of survivin.
Author:	Wang, Dawei\|Jiao, Chengbin\|Zhu, Yanli\|Liang, Deshen\|Zao, Ming\|Meng, Xiangyu\|Gao, Jianwei\|He, Yunlong\|Liu, Weixin\|Hou, Jie\|Zhong, Zhaohua\|Cheng, Zhuoxin
PMID:	27798120

102.
Journal:	Sci Rep. 2017 Feb 8;7:42226.
Title:	CXCL12/CXCR4 axis induced miR-125b promotes invasion and confers 5-fluorouracil resistance through enhancing autophagy in colorectal cancer.
Author:	Yu, Xinfeng\|Shi, Wenna\|Zhang, Yuhang\|Wang, Xiaohui\|Sun, Shiyue\|Song, Zhiyu\|Liu, Man\|Zeng, Qiao\|Cui, Shuxiang\|Qu, Xianjun
PMID:	28176874

103.
Journal:	Oncotarget. 2017 Jun 13;8(24):38351-38366.
Title:	Histone hypoacetylation contributes to CXCL12 downregulation in colon cancer: impact on tumor growth and cell migration.
Author:	Romain, Benoit\|Benbrika-Nehmar, Radhia\|Marisa, Laetitia\|Legrain, Michele\|Lobstein, Viviane\|Oravecz, Attila\|Poidevin, Laetitia\|Bour, Cyril\|Freund, Jean-Noel\|Duluc, Isabelle\|Guenot, Dominique\|Pencreach, Erwan
PMID:	28418886

104.
Journal:	Mol Clin Oncol. 2017 May;6(5):701-704.
Title:	Expression of CXCR-4 and IDO in human colorectal cancer: An immunohistochemical approach.
Author:	Ogawa, Masaichi\|Watanabe, Michiaki\|Hasegawa, Takuo\|Ichihara, Kohei\|Yoshida, Kazuhiko\|Yanaga, Katsuhiko
PMID:	28515923

105.
Journal:	Tumour Biol. 2017 Jun;39(6):1010428317706206.
Title:	Role of CXCR4 and SDF1 as prognostic factors for survival and the association with clinicopathology in colorectal cancer: A systematic meta-analysis.
Author:	Li, Yao-Ping\|Pang, Jing\|Gao, Sheng\|Bai, Peng-Yu\|Wang, Wen-da\|Kong, Pengzhou\|Cui, Yongping
PMID:	28621237

106.
Journal:	Anticancer Res. 2017 Aug;37(8):4361-4369.
Title:	The Axis of CXCR4/SDF-1 Plays a Role in Colon Cancer Cell Adhesion Through Regulation of the AKT and IGF1R Signalling Pathways.
Author:	Zheng, Fei\|Zhang, Zhongtao\|Flamini, Valentina\|Jiang, Wen G\|Cui, Yuxin
PMID:	28739729

107.
Journal:	Ann Surg. 2017 Nov;266(5):746-753.
Title:	The Allosteric Hemoglobin Effector ITPP Inhibits Metastatic Colon Cancer in Mice.
Author:	Limani, Perparim\|Linecker, Michael\|Schneider, Marcel A\|Kron, Philipp\|Tschuor, Christoph\|Kachaylo, Ekaterina\|Ungethuem, Udo\|Nicolau, Claude\|Lehn, Jean-Marie\|Graf, Rolf\|Humar, Bostjan\|Clavien, Pierre-Alain
PMID:	28742687

108.
Journal:	World J Gastroenterol. 2017 Jul 28;23(28):5167-5178.
Title:	Fibroblast-derived CXCL12/SDF-1alpha promotes CXCL6 secretion and co-operatively enhances metastatic potential through the PI3K/Akt/mTOR pathway in colon cancer.
Author:	Ma, Jia-Chi\|Sun, Xiao-Wen\|Su, He\|Chen, Quan\|Guo, Tian-Kang\|Li, Yuan\|Chen, Xiao-Chang\|Guo, Jin\|Gong, Zhen-Qiang\|Zhao, Xiao-Dan\|Qi, Jian-Bo
PMID:	28811711

109.
Journal:	Proc Natl Acad Sci U S A. 2017 Sep 26;114(39):10455-10460.
Title:	Targeting CXCR4-dependent immunosuppressive Ly6C(low) monocytes improves antiangiogenic therapy in colorectal cancer.
Author:	Jung, Keehoon\|Heishi, Takahiro\|Incio, Joao\|Huang, Yuhui\|Beech, Elizabeth Y\|Pinter, Matthias\|Ho, William W\|Kawaguchi, Kosuke\|Rahbari, Nuh N\|Chung, Euiheon\|Kim, Jun Ki\|Clark, Jeffrey W\|Willett, Christopher G\|Yun, Seok Hyun\|Luster, Andrew D\|Padera, Timothy P
PMID:	28900008

110.
Journal:	Cell Oncol (Dordr). 2017 Dec;40(6):609-619.
Title:	Phosphorylated CXCR4 expression has a positive prognostic impact in colorectal cancer.
Author:	Weixler, B\|Renetseder, F\|Facile, I\|Tosti, N\|Cremonesi, E\|Tampakis, A\|Delko, T\|Eppenberger-Castori, S\|Tzankov, A\|Iezzi, G\|Kettelhack, C\|Soysal, S D\|von Holzen, U\|Spagnoli, G C\|Terracciano, L\|Tornillo, L\|Droeser, Raoul A\|Daster, S
PMID:	28936810

111.
Journal:	Cancer Immunol Res. 2017 Nov;5(11):950-956.
Title:	Increasing Tumor-Infiltrating T Cells through Inhibition of CXCL12 with NOX-A12 Synergizes with PD-1 Blockade.
Author:	Zboralski, Dirk\|Hoehlig, Kai\|Eulberg, Dirk\|Fromming, Anna\|Vater, Axel
PMID:	28963140

112.
Journal:	Oncogene. 2018 Mar;37(9):1205-1219.
Title:	The impact of stromal Hic-5 on the tumorigenesis of colorectal cancer through lysyl oxidase induction and stromal remodeling.
Author:	Omoto, Tomokatsu\|Kim-Kaneyama, Joo-Ri\|Lei, Xiao-Feng\|Orimo, Akira\|Ohnishi, Koji\|Yoshihara, Kosuke\|Miyauchi, Aya\|Li, Shuo\|Gao, Lin\|Umemoto, Takahiro\|Tanaka, Junichi\|Nakahara, Kenta\|Takeya, Motohiro\|Ishida, Fumio\|Kudo, Shin-Ei\|Haraguchi, Shogo\|Miyazaki, Tak
PMID:	29242607

113.
Journal:	Clin Transl Oncol. 2018 Aug;20(8):1035-1045.
Title:	CXCL12 gene silencing down-regulates metastatic potential via blockage of MAPK/PI3K/AP-1 signaling pathway in colon cancer.
Author:	Ma, J\|Su, H\|Yu, B\|Guo, T\|Gong, Z\|Qi, J\|Zhao, X\|Du, J
PMID:	29305742

114.
Journal:	Oncol Rep. 2018 Apr;39(4):2022-2030.
Title:	CXCR4 receptor blockage reduces the contribution of tumor and stromal cells to the metastatic growth in the liver.
Author:	Benedicto, Aitor\|Romayor, Irene\|Arteta, Beatriz
PMID:	29436696

115.
Journal:	Gut. 2018 Feb 6. pii: gutjnl-2016-313498.
Title:	Gut microbiota modulate T cell trafficking into human colorectal cancer.
Author:	Cremonesi, Eleonora\|Governa, Valeria\|Garzon, Jesus Francisco Glaus\|Mele, Valentina\|Amicarella, Francesca\|Muraro, Manuele Giuseppe\|Trella, Emanuele\|Galati-Fournier, Virginie\|Oertli, Daniel\|Daster, Silvio Raffael\|Droeser, Raoul A\|Weixler, Benjamin\|Bolli, Ma
PMID:	29437871

116.
Journal:	Gastroenterology. 2018 Jun;154(8):2209-2221.e14.
Title:	P300 Acetyltransferase Mediates Stiffness-Induced Activation of Hepatic Stellate Cells Into Tumor-Promoting Myofibroblasts.
Author:	Dou, Changwei\|Liu, Zhikui\|Tu, Kangsheng\|Zhang, Hongbin\|Chen, Chen\|Yaqoob, Usman\|Wang, Yuanguo\|Wen, Jialing\|van Deursen, Jan\|Sicard, Delphine\|Tschumperlin, Daniel\|Zou, Hongzhi\|Huang, Wei-Chien\|Urrutia, Raul\|Shah, Vijay H\|Kang, Ningling
PMID:	29454793

117.
Journal:	Clin Lab. 2018 May 1;64(5):871-876.
Title:	Expression Patterns of CXCL12 and its Receptor in Colorectal Carcinoma.
Author:	Mousavi, Ashraf\|Hashemzadeh, Shahryar\|Bahrami, Tayyeb\|Estiar, Mehrdad Asghari\|Feizi, Mohammad A H\|Pouladi, Nasser\|Rostamizadeh, Leila\|Sakhinia, Ebrahim
PMID:	29739049

118.
Journal:	Onco Targets Ther. 2018 May 1;11:2445-2452.
Title:	The CXCL12 rs1801157 polymorphism and risk of colorectal cancer: a meta-analysis.
Author:	Xu, Ke\|Dai, Hong\|Wang, Shaolong\|Zhang, Jie\|Liu, Tao
PMID:	29760554

119.
Journal:	Gastroenterol Res Pract. 2018 May 16;2018:9613185.
Title:	Clinicopathologic Significance of CXCL12 and CXCR4 Expressions in Patients with Colorectal Cancer.
Author:	Yoshuantari, Naomi\|Heriyanto, Didik Setyo\|Hutajulu, Susanna Hilda\|Kurnianda, Johan\|Ghozali, Ahmad
PMID:	29887884

120.
Journal:	EBioMedicine. 2018 Sep 19. pii: S2352-3964(18)30379-7.
Title:	Profiles of alternative splicing in colorectal cancer and their clinical significance: A study based on large-scale sequencing data.
Author:	Xiong, Yongfu\|Deng, Ying\|Wang, Kang\|Zhou, He\|Zheng, Xiangru\|Si, Liangyi\|Fu, Zhongxue
PMID:	30243491

121.
Journal:	Biosci Rep. 2018 Oct 24. pii: BSR20180243.
Title:	Integrin alphavbeta6 Plays an Bi-directional Regulation Role Between Colon Cancer cells and Cancer-Associated Fibroblasts.
Author:	Peng, Cheng\|Zou, Xueqing\|Xia, Wanying\|Gao, Huijie\|Li, Zequn\|Liu, Naiqing\|Xu, Zongquan\|Gao, Chao\|He, Zhaobin\|Niu, Weibo\|Fang, Ruliang\|Biswas, Siddhartha\|Agrez, Michael\|Zhi, Xuting\|Niu, Jun
PMID:	30355650