Primary Site >> Colorectal Cancer

Gene >> CXCL10

Journal: Clin Cancer Res. 2005 Jun 1;11(11):4217-24.
Title: Improved therapeutic effectiveness by combining recombinant CXC chemokine ligand 10 with Cisplatin in solid tumors.
Author: Li, Gang|Tian, Ling|Hou, Jian-Mei|Ding, Zhen-Yu|He, Qiu-Ming|Feng, Ping|Wen, Yan-Jun|Xiao, Fei|Yao, Bing|Zhang, Ru|Peng, Feng|Jiang, Yu|Luo, Feng|Zhao, Xia|Zhang, Lin|Zhou, Qiao|Wei, Yu-Quan
PMID: 15930360
Journal: Int J Cancer. 2005 Oct 10;116(6):949-56.
Title: Selective infiltration of CCR5(+)CXCR3(+) T lymphocytes in human colorectal carcinoma.
Author: Musha, Hiroaki|Ohtani, Haruo|Mizoi, Takayuki|Kinouchi, Makoto|Nakayama, Takashi|Shiiba, Kennichi|Miyagawa, Kikuo|Nagura, Hiroshi|Yoshie, Osamu|Sasaki, Iwao
PMID: 15856455
Journal: Cancer Res. 2007 Apr 1;67(7):3396-405.
Title: CXCL10 promotes invasion-related properties in human colorectal carcinoma cells.
Author: Zipin-Roitman, Adi|Meshel, Tsipi|Sagi-Assif, Orit|Shalmon, Bruria|Avivi, Camila|Pfeffer, Raphael M|Witz, Isaac P|Ben-Baruch, Adit
PMID: 17409450
Journal: Gastroenterology. 2007 Jul;133(1):108-23.
Title: Fenofibrate represses interleukin-17 and interferon-gamma expression and improves colitis in interleukin-10-deficient mice.
Author: Lee, Jimmy W|Bajwa, Poonam J|Carson, Monica J|Jeske, Daniel R|Cong, Yingzi|Elson, Charles O|Lytle, Christian|Straus, Daniel S
PMID: 17631136
Journal: Int J Cancer. 2008 Nov 1;123(9):2120-9.
Title: Angiostatic immune reaction in colorectal carcinoma: Impact on survival and perspectives for antiangiogenic therapy.
Author: Naschberger, Elisabeth|Croner, Roland S|Merkel, Susanne|Dimmler, Arno|Tripal, Philipp|Amann, Kerstin U|Kremmer, Elisabeth|Brueckl, Wolfgang M|Papadopoulos, Thomas|Hohenadl, Christine|Hohenberger, Werner|Sturzl, Michael
PMID: 18697200
Journal: Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2835-45.
Title: Diagnostic mRNA expression patterns of inflamed, benign, and malignant colorectal biopsy specimen and their correlation with peripheral blood results.
Author: Galamb, Orsolya|Sipos, Ferenc|Solymosi, Norbert|Spisak, Sandor|Krenacs, Tibor|Toth, Kinga|Tulassay, Zsolt|Molnar, Bela
PMID: 18843029
Journal: Cancer Immunol Immunother. 2009 Jan;58(1):85-94.
Title: Expression and function of T cell homing molecules in Hodgkin's lymphoma.
Author: Machado, Lee|Jarrett, Ruth|Morgan, Susan|Murray, Paul|Hunter, Beatrix|Hamilton, Emma|Crocker, John|Thomas, Wendy|Steven, Neil|Ismail, Tariq|Chapman, Ann|Adams, David H|Lee, Steven P
PMID: 18488221
Journal: Methods Enzymol. 2009;460:105-21.
Title: Expression of chemokines and chemokine receptors in human colon cancer.
Author: Erreni, Marco|Bianchi, Paolo|Laghi, Luigi|Mirolo, Massimiliano|Fabbri, Marco|Locati, Massimo|Mantovani, Alberto|Allavena, Paola
PMID: 19446722
Journal: Cancer Immunol Immunother. 2010 Nov;59(11):1715-26.
Title: Integrating individual functional moieties of CXCL10 and CXCL11 into a novel chimeric chemokine leads to synergistic antitumor effects: a strategy for chemokine-based multi-target-directed cancer therapy.
Author: Wang, Ping|Yang, Xiuli|Xu, Wei|Li, Kang|Chu, Yiwei|Xiong, Sidong
PMID: 20706716
Journal: Mol Cancer. 2010 Oct 14;9:273.
Title: Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12.
Author: Rigo, Antonella|Gottardi, Michele|Zamo, Alberto|Mauri, Pierluigi|Bonifacio, Massimiliano|Krampera, Mauro|Damiani, Ernesto|Pizzolo, Giovanni|Vinante, Fabrizio
PMID: 20946648
Journal: Hum Pathol. 2010 Jul;41(7):990-1001.
Title: Expression of angiostatic platelet factor-4var/CXCL4L1 counterbalances angiogenic impulses of vascular endothelial growth factor, interleukin-8/CXCL8, and stromal cell-derived factor 1/CXCL12 in esophageal and colorectal cancer.
Author: Verbeke, Hannelien|De Hertogh, Gert|Li, Sandra|Vandercappellen, Jo|Noppen, Samuel|Schutyser, Evemie|El-Asrar, Ahmed Abu|Opdenakker, Ghislain|Van Damme, Jo|Geboes, Karel|Struyf, Sofie
PMID: 20334899
Journal: Gastroenterology. 2010 Apr;138(4):1429-40.
Title: Biomolecular network reconstruction identifies T-cell homing factors associated with survival in colorectal cancer.
Author: Mlecnik, Bernhard|Tosolini, Marie|Charoentong, Pornpimol|Kirilovsky, Amos|Bindea, Gabriela|Berger, Anne|Camus, Matthieu|Gillard, Melanie|Bruneval, Patrick|Fridman, Wolf-Herman|Pages, Franck|Trajanoski, Zlatko|Galon, Jerome
PMID: 19909745
Journal: Mol Biol Rep. 2010 Jul;37(6):3029-36.
Title: CXCL10 expression and prognostic significance in stage II and III colorectal cancer.
Author: Jiang, Zheng|Xu, Ye|Cai, Sanjun
PMID: 19821051
Journal: Int Immunopharmacol. 2011 Dec;11(12):2104-11.
Title: 3'-Chloro-5,7-dimethoxyisoflavone inhibits TNFalpha-induced CXCL10 gene transcription by suppressing the NF-kappaB pathway in HCT116 human colon cancer cells.
Author: Shin, Soon Young|Hyun, Jiye|Lim, Yoongho|Lee, Young Han
PMID: 21945666
Journal: Int J Oncol. 2012 Feb;40(2):560-6.
Title: Evaluation of CXCL10 as a novel serum marker for predicting liver metastasis and prognosis in colorectal cancer.
Author: Toiyama, Yuji|Fujikawa, Hiroyuki|Kawamura, Mikio|Matsushita, Kohei|Saigusa, Susumu|Tanaka, Koji|Inoue, Yasuhiro|Uchida, Keiichi|Mohri, Yasuhiko|Kusunoki, Masato
PMID: 22038159
Journal: Gut. 2012 Nov;61(11):1560-7.
Title: ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis.
Author: Agesen, Trude H|Sveen, Anita|Merok, Marianne A|Lind, Guro E|Nesbakken, Arild|Skotheim, Rolf I|Lothe, Ragnhild A
PMID: 22213796
Journal: Cancer Res. 2012 Aug 1;72(15):3735-43.
Title: NF-kappaB hyperactivation in tumor tissues allows tumor-selective reprogramming of the chemokine microenvironment to enhance the recruitment of cytolytic T effector cells.
Author: Muthuswamy, Ravikumar|Berk, Erik|Junecko, Beth Fallert|Zeh, Herbert J|Zureikat, Amer H|Normolle, Daniel|Luong, The Minh|Reinhart, Todd A|Bartlett, David L|Kalinski, Pawel
PMID: 22593190
Journal: Int J Cancer. 2013 Feb 1;132(3):591-604.
Title: Inhibition of GTP cyclohydrolase attenuates tumor growth by reducing angiogenesis and M2-like polarization of tumor associated macrophages.
Author: Pickert, Geethanjali|Lim, Hee-Young|Weigert, Andreas|Haussler, Annett|Myrczek, Thekla|Waldner, Maximilian|Labocha, Sandra|Ferreiros, Nerea|Geisslinger, Gerd|Lotsch, Jorn|Becker, Christoph|Brune, Bernhard|Tegeder, Irmgard
PMID: 22753274
Journal: Biochem Pharmacol. 2013 Feb 1;85(3):396-403.
Title: IFNalpha converts IL-22 into a cytokine efficiently activating STAT1 and its downstream targets.
Author: Bachmann, Malte|Ulziibat, Solongo|Hardle, Lorena|Pfeilschifter, Josef|Muhl, Heiko
PMID: 23153456
Journal: Oncoimmunology. 2014 Jun 25;3:e29256.
Title: Characterization of an adaptive immune response in microsatellite-instable colorectal cancer.
Author: Boissiere-Michot, Florence|Lazennec, Gwendal|Frugier, Helene|Jarlier, Marta|Roca, Lise|Duffour, Jacqueline|Du Paty, Emilie|Laune, Daniel|Blanchard, France|Le Pessot, Florence|Sabourin, Jean-Christophe|Bibeau, Frederic
PMID: 25101223
Journal: Tumour Biol. 2014 Oct;35(10):9683-91.
Title: CXCL10 mRNA expression predicts response to neoadjuvant chemoradiotherapy in rectal cancer patients.
Author: Li, Cong|Wang, Zhimin|Liu, Fangqi|Zhu, Ji|Yang, Li|Cai, Guoxiang|Zhang, Zhen|Huang, Wei|Cai, Sanjun|Xu, Ye
PMID: 24969558
Journal: Biomed Pharmacother. 2014 Jun;68(5):551-6.
Title: Modification of chemokine receptor expression to enhance levels of trafficking receptors on autologous cytokine-induced killer cells derived from patients with colorectal cancer.
Author: Wang, Dan|Li, Jing|Liu, Jin-Yan|Li, Feng|Wang, Li-Ping|Huang, Lan|Li, Jie-Yao|Chen, Xin-Feng|Liu, Jin-Bo|Wu, Chang-Cai|Yuan, Wei-Tang|Wang, Gui-Xian|Song, Jun-Min|Yue, Dong-Li|Zhang, Zhen|Ping, Yu|Wang, Rui-Rui|Zhang, Jian-Ying|Zhang, Yi
PMID: 24855035
Journal: Biomed Rep. 2014 May;2(3):340-343.
Title: Protein expression and gene polymorphism of CXCL10 in patients with colorectal cancer.
Author: Dimberg, Jan|Skarstedt, Marita|Lofgren, Sture|Zar, Niklas|Matussek, Andreas
PMID: 24748971
Journal: World J Gastroenterol. 2014 Mar 21;20(11):2979-94.
Title: Differential gene expression of chemokines in KRAS and BRAF mutated colorectal cell lines: role of cytokines.
Author: Khan, Sajjad|Cameron, Silke|Blaschke, Martina|Moriconi, Federico|Naz, Naila|Amanzada, Ahmad|Ramadori, Giuliano|Malik, Ihtzaz Ahmed
PMID: 24659889
Journal: Bioorg Med Chem. 2014 Jun 1;22(11):2912-8.
Title: Anti-inflammatory drimane sesquiterpene lactones from an Aspergillus species.
Author: Felix, Silke|Sandjo, Louis P|Opatz, Till|Erkel, Gerhard
PMID: 24792812
Journal: Oncotarget. 2015 Feb 20;6(5):2981-91.
Title: Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration.
Author: Zumwalt, Timothy J|Arnold, Mildred|Goel, Ajay|Boland, C Richard
PMID: 25671296
Journal: Eur J Immunol. 2015 Jun;45(6):1654-66.
Title: Treg-cell depletion promotes chemokine production and accumulation of CXCR3(+) conventional T cells in intestinal tumors.
Author: Akeus, Paulina|Langenes, Veronica|Kristensen, Jonas|von Mentzer, Astrid|Sparwasser, Tim|Raghavan, Sukanya|Quiding-Jarbrink, Marianne
PMID: 25754875
Journal: Oncotarget. 2015 Aug 14;6(23):19792-806.
Title: Heme oxygenase-1 promotes tumor progression and metastasis of colorectal carcinoma cells by inhibiting antitumor immunity.
Author: Seo, Geom Seog|Jiang, Wen-Yi|Chi, Jin Hua|Jin, Hao|Park, Won-Chul|Sohn, Dong Hwan|Park, Pil-Hoon|Lee, Sung Hee
PMID: 26087182
Journal: PLoS One. 2015 Jul 2;10(7):e0131699.
Title: Cell Free DNA of Tumor Origin Induces a 'Metastatic' Expression Profile in HT-29 Cancer Cell Line.
Author: Furi, Istvan|Kalmar, Alexandra|Wichmann, Barnabas|Spisak, Sandor|Scholler, Andrea|Bartak, Barbara|Tulassay, Zsolt|Molnar, Bela
PMID: 26133168
Journal: Oncotarget. 2015 Oct 20;6(32):32561-74.
Title: An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer.
Author: Agostini, Marco|Janssen, Klaus-Peter|Kim, Il-Jin|D'Angelo, Edoardo|Pizzini, Silvia|Zangrando, Andrea|Zanon, Carlo|Pastrello, Chiara|Maretto, Isacco|Digito, Maura|Bedin, Chiara|Jurisica, Igor|Rizzolio, Flavio|Giordano, Antonio|Bortoluzzi, Stefania|Nitti, D
PMID: 26359356
Journal: BMC Cancer. 2016 Mar 7;16:189.
Title: Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation.
Author: Shukla, Pradeep K|Chaudhry, Kamaljit K|Mir, Hina|Gangwar, Ruchika|Yadav, Nikki|Manda, Bhargavi|Meena, Avtar S|Rao, RadhaKrishna
PMID: 26951793
Journal: J Pathol Clin Res. 2015 Oct 28;2(1):21-31.
Title: The infiltration, and prognostic importance, of Th1 lymphocytes vary in molecular subgroups of colorectal cancer.
Author: Ling, Agnes|Lundberg, Ida V|Eklof, Vincy|Wikberg, Maria L|Oberg, Ake|Edin, Sofia|Palmqvist, Richard
PMID: 27499912
Journal: Cancer Cell. 2016 Apr 11;29(4):587-601.
Title: Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients.
Author: Halama, Niels|Zoernig, Inka|Berthel, Anna|Kahlert, Christoph|Klupp, Fee|Suarez-Carmona, Meggy|Suetterlin, Thomas|Brand, Karsten|Krauss, Juergen|Lasitschka, Felix|Lerchl, Tina|Luckner-Minden, Claudia|Ulrich, Alexis|Koch, Moritz|Weitz, Juergen|Schneider, Ma
PMID: 27070705
Journal: Oncotarget. 2016 May 10;7(19):27394-407.
Title: Neuroendocrine-like cells -derived CXCL10 and CXCL11 induce the infiltration of tumor-associated macrophage leading to the poor prognosis of colorectal cancer.
Author: Zeng, Yu-Jie|Lai, Wei|Wu, Heng|Liu, Lu|Xu, He-Yang|Wang, Jie|Chu, Zhong-Hua
PMID: 27034164
Journal: Br J Cancer. 2016 Mar 15;114(6):697-703.
Title: Ectopic expression of the chemokine CXCL17 in colon cancer cells.
Author: Ohlsson, Lina|Hammarstrom, Marie-Louise|Lindmark, Gudrun|Hammarstrom, Sten|Sitohy, Basel
PMID: 26889977
Journal: Mol Clin Oncol. 2016 Jan;4(1):23-30.
Title: CXCL10/CXCR3 overexpression as a biomarker of poor prognosis in patients with stage II colorectal cancer.
Author: Bai, Ming|Chen, Xia|Ba, Y I
PMID: 26870351
Journal: Sci Rep. 2016 Jan 11;6:18772.
Title: Low adherent cancer cell subpopulations are enriched in tumorigenic and metastatic epithelial-to-mesenchymal transition-induced cancer stem-like cells.
Author: Morata-Tarifa, Cynthia|Jimenez, Gema|Garcia, Maria A|Entrena, Jose M|Grinan-Lison, Carmen|Aguilera, Margarita|Picon-Ruiz, Manuel|Marchal, Juan A
PMID: 26752044
Journal: Cancer Res. 2016 Jan 15;76(2):275-82.
Title: PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer.
Author: Nagarsheth, Nisha|Peng, Dongjun|Kryczek, Ilona|Wu, Ke|Li, Wei|Zhao, Ende|Zhao, Lili|Wei, Shuang|Frankel, Timothy|Vatan, Linda|Szeliga, Wojciech|Dou, Yali|Owens, Scott|Marquez, Victor|Tao, Kaixiong|Huang, Emina|Wang, Guobin|Zou, Weiping
PMID: 26567139
Journal: Ann Surg Oncol. 2016 Feb;23(2):655-62.
Title: Complement Inhibition: A Novel Form of Immunotherapy for Colon Cancer.
Author: Downs-Canner, Stephanie|Magge, Deepa|Ravindranathan, Roshni|O'Malley, Mark E|Francis, Lily|Liu, Zuqiang|Sheng Guo, Z|Obermajer, Natasa|Bartlett, David L
PMID: 26289805
Journal: Colorectal Dis. 2017 May;19(5):O115-O125.
Title: Peripheral blood leucocytes show differential expression of tumour progression-related genes in colorectal cancer patients who have a postoperative intra-abdominal infection: a prospective matched cohort study.
Author: Alonso, S|Mayol, X|Nonell, L|Salvans, S|Pascual, M|Pera, M
PMID: 28214365
Journal: Cancer Immunol Immunother. 2017 Jun;66(6):705-716.
Title: Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site.
Author: Ohkuri, Takayuki|Kosaka, Akemi|Ishibashi, Kei|Kumai, Takumi|Hirata, Yui|Ohara, Kenzo|Nagato, Toshihiro|Oikawa, Kensuke|Aoki, Naoko|Harabuchi, Yasuaki|Celis, Esteban|Kobayashi, Hiroya
PMID: 28243692
Journal: Oncotarget. 2017 Sep 28;8(52):89998-90012.
Title: Interferon-inducible CXC-chemokines are crucial immune modulators and survival predictors in colorectal cancer.
Author: Kistner, Larissa|Doll, Dietrich|Holtorf, Anne|Nitsche, Ulrich|Janssen, Klaus-Peter
PMID: 29163806
Journal: Clin Cancer Res. 2018 Jan 1;24(1):224-233.
Title: KRAS Mutation and Consensus Molecular Subtypes 2 and 3 Are Independently Associated with Reduced Immune Infiltration and Reactivity in Colorectal Cancer.
Author: Lal, Neeraj|White, Brian S|Goussous, Ghaleb|Pickles, Oliver|Mason, Mike J|Beggs, Andrew D|Taniere, Philippe|Willcox, Benjamin E|Guinney, Justin|Middleton, Gary W
PMID: 29061646
Journal: Gut. 2018 Feb 6. pii: gutjnl-2016-313498.
Title: Gut microbiota modulate T cell trafficking into human colorectal cancer.
Author: Cremonesi, Eleonora|Governa, Valeria|Garzon, Jesus Francisco Glaus|Mele, Valentina|Amicarella, Francesca|Muraro, Manuele Giuseppe|Trella, Emanuele|Galati-Fournier, Virginie|Oertli, Daniel|Daster, Silvio Raffael|Droeser, Raoul A|Weixler, Benjamin|Bolli, Ma
PMID: 29437871
Journal: Oncol Lett. 2018 Mar;15(3):3876-3882.
Title: Distinctive profiles of tumor-infiltrating immune cells and association with intensity of infiltration in colorectal cancer.
Author: Wu, Yugang|Yuan, Lei|Lu, Qicheng|Xu, Haiyan|He, Xiaozhou
PMID: 29456737
Journal: Cancer Immunol Res. 2018 May;6(5):578-593.
Title: Protumor Steering of Cancer Inflammation by p50 NF-kappaB Enhances Colorectal Cancer Progression.
Author: Porta, Chiara|Ippolito, Alessandro|Consonni, Francesca Maria|Carraro, Lorenzo|Celesti, Giuseppe|Correale, Carmen|Grizzi, Fabio|Pasqualini, Fabio|Tartari, Silvia|Rinaldi, Maurizio|Bianchi, Paolo|Balzac, Fiorella|Vetrano, Stefania|Turco, Emilia|Hirsch, Emil
PMID: 29588321
Journal: Cell Commun Signal. 2018 Apr 24;16(1):17.
Title: Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages.
Author: Popena, Ineta|Abols, Arturs|Saulite, Liga|Pleiko, Karlis|Zandberga, Elina|Jekabsons, Kaspars|Endzelins, Edgars|Llorente, Alicia|Line, Aija|Riekstina, Una
PMID: 29690889
Journal: Oncogene. 2018 Sep 10. pii: 10.1038/s41388-018-0492-9.
Title: Loss of solute carrier family 7 member 2 exacerbates inflammation-associated colon tumorigenesis.
Author: Coburn, Lori A|Singh, Kshipra|Asim, Mohammad|Barry, Daniel P|Allaman, Margaret M|Al-Greene, Nicole T|Hardbower, Dana M|Polosukhina, Dina|Williams, Christopher S|Delgado, Alberto G|Piazuelo, M Blanca|Washington, M Kay|Gobert, Alain P|Wilson, Keith T
PMID: 30202097
Journal: Biol Pharm Bull. 2018 Nov 1.
Title: Forced expression of CXCL10 prevents liver metastasis of colon carcinoma cells by the recruitment of natural killer cells.
Author: Kikuchi, Norihito|Ye, Jiabin|Hirakawa, Jotaro|Kawashima, Hiroto
PMID: 30381616