Primary Site >> Colorectal Cancer
Gene >> CXCL10
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Ref: Selective infiltration of CCR5(+)CXCR3(+) T lymphocytes in human colorectal carcinoma. PMID: 15856455 Ref: Improved therapeutic effectiveness by combining recombinant CXC chemokine ligand 10 with Cisplatin in solid tumors. PMID: 15930360 |
Ref: CXCL10 promotes invasion-related properties in human colorectal carcinoma cells. PMID: 17409450 Ref: Fenofibrate represses interleukin-17 and interferon-gamma expression and improves colitis in interleukin-10-deficient mice. PMID: 17631136 |
Ref: Angiostatic immune reaction in colorectal carcinoma: Impact on survival and perspectives for antiangiogenic therapy. PMID: 18697200 Ref: Diagnostic mRNA expression patterns of inflamed, benign, and malignant colorectal biopsy specimen and their correlation with peripheral blood results. PMID: 18843029 |
Ref: Expression and function of T cell homing molecules in Hodgkin's lymphoma. PMID: 18488221 Ref: Expression of chemokines and chemokine receptors in human colon cancer. PMID: 19446722 |
Ref: CXCL10 expression and prognostic significance in stage II and III colorectal cancer. PMID: 19821051 Ref: Biomolecular network reconstruction identifies T-cell homing factors associated with survival in colorectal cancer. PMID: 19909745 Ref: Expression of angiostatic platelet factor-4var/CXCL4L1 counterbalances angiogenic impulses of vascular endothelial growth factor, interleukin-8/CXCL8, and stromal cell-derived factor 1/CXCL12 in esophageal and colorectal cancer. PMID: 20334899 Ref: Integrating individual functional moieties of CXCL10 and CXCL11 into a novel chimeric chemokine leads to synergistic antitumor effects: a strategy for chemokine-based multi-target-directed cancer therapy. PMID: 20706716 Ref: Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12. PMID: 20946648 |
Ref: 3'-Chloro-5,7-dimethoxyisoflavone inhibits TNFalpha-induced CXCL10 gene transcription by suppressing the NF-kappaB pathway in HCT116 human colon cancer cells. PMID: 21945666 |
Ref: Evaluation of CXCL10 as a novel serum marker for predicting liver metastasis and prognosis in colorectal cancer. PMID: 22038159 Ref: ColoGuideEx: a robust gene classifier specific for stage II colorectal cancer prognosis. PMID: 22213796 Ref: NF-kappaB hyperactivation in tumor tissues allows tumor-selective reprogramming of the chemokine microenvironment to enhance the recruitment of cytolytic T effector cells. PMID: 22593190 |
Ref: Inhibition of GTP cyclohydrolase attenuates tumor growth by reducing angiogenesis and M2-like polarization of tumor associated macrophages. PMID: 22753274 Ref: IFNalpha converts IL-22 into a cytokine efficiently activating STAT1 and its downstream targets. PMID: 23153456 |
Ref: Differential gene expression of chemokines in KRAS and BRAF mutated colorectal cell lines: role of cytokines. PMID: 24659889 Ref: Protein expression and gene polymorphism of CXCL10 in patients with colorectal cancer. PMID: 24748971 Ref: Anti-inflammatory drimane sesquiterpene lactones from an Aspergillus species. PMID: 24792812 Ref: Modification of chemokine receptor expression to enhance levels of trafficking receptors on autologous cytokine-induced killer cells derived from patients with colorectal cancer. PMID: 24855035 Ref: CXCL10 mRNA expression predicts response to neoadjuvant chemoradiotherapy in rectal cancer patients. PMID: 24969558 Ref: Characterization of an adaptive immune response in microsatellite-instable colorectal cancer. PMID: 25101223 |
Ref: Active secretion of CXCL10 and CCL5 from colorectal cancer microenvironments associates with GranzymeB+ CD8+ T-cell infiltration. PMID: 25671296 Ref: Treg-cell depletion promotes chemokine production and accumulation of CXCR3(+) conventional T cells in intestinal tumors. PMID: 25754875 Ref: Heme oxygenase-1 promotes tumor progression and metastasis of colorectal carcinoma cells by inhibiting antitumor immunity. PMID: 26087182 Ref: Cell Free DNA of Tumor Origin Induces a 'Metastatic' Expression Profile in HT-29 Cancer Cell Line. PMID: 26133168 Ref: An integrative approach for the identification of prognostic and predictive biomarkers in rectal cancer. PMID: 26359356 |
Ref: Complement Inhibition: A Novel Form of Immunotherapy for Colon Cancer. PMID: 26289805 Ref: PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer. PMID: 26567139 Ref: Low adherent cancer cell subpopulations are enriched in tumorigenic and metastatic epithelial-to-mesenchymal transition-induced cancer stem-like cells. PMID: 26752044 Ref: CXCL10/CXCR3 overexpression as a biomarker of poor prognosis in patients with stage II colorectal cancer. PMID: 26870351 Ref: Ectopic expression of the chemokine CXCL17 in colon cancer cells. PMID: 26889977 Ref: Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation. PMID: 26951793 Ref: Neuroendocrine-like cells -derived CXCL10 and CXCL11 induce the infiltration of tumor-associated macrophage leading to the poor prognosis of colorectal cancer. PMID: 27034164 Ref: Tumoral Immune Cell Exploitation in Colorectal Cancer Metastases Can Be Targeted Effectively by Anti-CCR5 Therapy in Cancer Patients. PMID: 27070705 Ref: The infiltration, and prognostic importance, of Th1 lymphocytes vary in molecular subgroups of colorectal cancer. PMID: 27499912 |
Ref: Peripheral blood leucocytes show differential expression of tumour progression-related genes in colorectal cancer patients who have a postoperative intra-abdominal infection: a prospective matched cohort study. PMID: 28214365 Ref: Intratumoral administration of cGAMP transiently accumulates potent macrophages for anti-tumor immunity at a mouse tumor site. PMID: 28243692 Ref: Interferon-inducible CXC-chemokines are crucial immune modulators and survival predictors in colorectal cancer. PMID: 29163806 |
Ref: KRAS Mutation and Consensus Molecular Subtypes 2 and 3 Are Independently Associated with Reduced Immune Infiltration and Reactivity in Colorectal Cancer. PMID: 29061646 Ref: Gut microbiota modulate T cell trafficking into human colorectal cancer. PMID: 29437871 Ref: Distinctive profiles of tumor-infiltrating immune cells and association with intensity of infiltration in colorectal cancer. PMID: 29456737 Ref: Protumor Steering of Cancer Inflammation by p50 NF-kappaB Enhances Colorectal Cancer Progression. PMID: 29588321 Ref: Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages. PMID: 29690889 Ref: Loss of solute carrier family 7 member 2 exacerbates inflammation-associated colon tumorigenesis. PMID: 30202097 Ref: Forced expression of CXCL10 prevents liver metastasis of colon carcinoma cells by the recruitment of natural killer cells. PMID: 30381616 |