Primary Site >> Pancreatic Cancer
Gene >> CTSB
| 1. | |||||||||||
| Journal: | Cancer Metastasis Rev. 1984;3(3):249-63. | ||||||||||
| Title: | Cysteine proteinases and metastasis. | ||||||||||
| Author: | Sloane, B F|Honn, K V | ||||||||||
| PMID: | 6093995 | ||||||||||
| 2. | |||||||||||
| Journal: | Gastroenterol Jpn. 1989 Dec;24(6):699-706. | ||||||||||
| Title: | Variant cathepsin B activity secreted from human pancreatic cancer cell lines into protein-free chemically defined medium. | ||||||||||
| Author: | Chung, S M|Kawai, K | ||||||||||
| PMID: | 2606304 | ||||||||||
| 3. | |||||||||||
| Journal: | Br J Cancer. 1994 Jan;69(1):152-6. | ||||||||||
| Title: | Pancreatic trypsinogen and cathepsin B in human pancreatic carcinomas and associated metastatic lesions. | ||||||||||
| Author: | Ohta, T|Terada, T|Nagakawa, T|Tajima, H|Itoh, H|Fonseca, L|Miyazaki, I | ||||||||||
| PMID: | 8286198 | ||||||||||
| 4. | |||||||||||
| Journal: | Oncol Rep. 1994 May;1(3):543-6. | ||||||||||
| Title: | Immunohistochemical study on cathepsin-B and cathepsin-d in pancreatic-cancer. | ||||||||||
| Author: | Nakata, B|Appert, H|Lei, S|Yamashita, Y|Chung, Y|Sowa, M|Myles, J|Mao, C|Howard, J | ||||||||||
| PMID: | 21607400 | ||||||||||
| 5. | |||||||||||
| Journal: | Pancreas. 1995 Mar;10(2):167-72. | ||||||||||
| Title: | Intracellular degradation of the C-peptide of proinsulin, in a human insulinoma: identification of sites of cleavage and evidence for a role for cathepsin B. | ||||||||||
| Author: | Conlon, J M|Hoog, A|Grimelius, L | ||||||||||
| PMID: | 7716141 | ||||||||||
| 6. | |||||||||||
| Journal: | Int J Gastrointest Cancer. 2003;34(1):27-38. | ||||||||||
| Title: | The metastatic potential of human pancreatic cell lines in the liver of nude mice correlates well with cathepsin B activity. | ||||||||||
| Author: | Tzanakakis, George N|Margioris, Andrew N|Tsatsakis, Aristidis M|Vezeridis, Michael P | ||||||||||
| PMID: | 15235133 | ||||||||||
| 7. | |||||||||||
| Journal: | Bioconjug Chem. 2004 May-Jun;15(3):647-57. | ||||||||||
| Title: | Evaluation of cleavable (Tyr3)-octreotate derivatives for longer intracellular probe residence. | ||||||||||
| Author: | Whetstone, Paul A|Akizawa, Hiromichi|Meares, Claude F | ||||||||||
| PMID: | 15149193 | ||||||||||
| 8. | |||||||||||
| Journal: | J Biol Chem. 2006 Apr 28;281(17):11923-32. Epub 2006 Jan 30. | ||||||||||
| Title: | PS-341 (bortezomib) induces lysosomal cathepsin B release and a caspase-2-dependent mitochondrial permeabilization and apoptosis in human pancreatic cancer cells. | ||||||||||
| Author: | Yeung, Bonnie H Y|Huang, Der-Chen|Sinicrope, Frank A | ||||||||||
| PMID: | 16446371 | ||||||||||
| 9. | |||||||||||
| Journal: | Anticancer Drugs. 2006 Nov;17(10):1119-26. | ||||||||||
| Title: | Human and murine macrophages mediate activation of MEN 4901/T-0128: a new promising camptothecin analogue-polysaccharide conjugate. | ||||||||||
| Author: | Binaschi, Monica|Parlani, Massimo|Bellarosa, Daniela|Bigioni, Mario|Salvatore, Carmela|Palma, Carla|Crea, Attilio|Maggi, Carlo Alberto|Manzini, Stefano|Goso, Cristina | ||||||||||
| PMID: | 17075311 | ||||||||||
| 10. | |||||||||||
| Journal: | Cancer Res. 2008 Aug 1;68(15):6313-23. | ||||||||||
| Title: | Bobel-24 and derivatives induce caspase-independent death in pancreatic cancer regardless of apoptotic resistance. | ||||||||||
| Author: | Parreno, Matilde|Casanova, Isolda|Cespedes, Maria Virtudes|Vaque, Jose Pedro|Pavon, Miguel Angel|Leon, Javier|Mangues, Ramon | ||||||||||
| PMID: | 18676856 | ||||||||||
| 11. | |||||||||||
| Journal: | Eur J Cancer Prev. 2008 Oct;17(5):438-45. | ||||||||||
| Title: | Serum cathepsin B and plasma urokinase-type plasminogen activator levels in gastrointestinal tract cancers. | ||||||||||
| Author: | Herszenyi, Laszlo|Istvan, Gabor|Cardin, Romilda|De Paoli, Massimo|Plebani, Mario|Tulassay, Zsolt|Farinati, Fabio | ||||||||||
| PMID: | 18714186 | ||||||||||
| 12. | |||||||||||
| Journal: | Cancer Genomics Proteomics. 2008 Sep-Oct;5(5):263-73. | ||||||||||
| Title: | Tissue microarrays of human tumor xenografts: characterization of proteins involved in migration and angiogenesis for applications in the development of targeted anticancer agents. | ||||||||||
| Author: | Smith, Victoria|Wirth, Gregory J|Fiebig, Heinz-Herbert|Burger, Angelika M | ||||||||||
| PMID: | 19129557 | ||||||||||
| 13. | |||||||||||
| Journal: | Chin Med J (Engl). 2009 Oct 20;122(20):2489-96. | ||||||||||
| Title: | Preliminary research on the pathological role of cathepsin-B in subcutaneous heteroplastic pancreatic carcinoma in nude mice. | ||||||||||
| Author: | Zhang, Chong|Sun, Jia-bang|Liu, Da-chuan|Cui, Ye-qing|Liu, Shuang|Sun, Hai-chen | ||||||||||
| PMID: | 20079165 | ||||||||||
| 14. | |||||||||||
| Journal: | Biochemistry. 2009 Apr 21;48(15):3519-26. | ||||||||||
| Title: | Designing protease sensors for real-time imaging of trypsin activation in pancreatic cancer cells. | ||||||||||
| Author: | Chen, Ning|Zou, Jin|Wang, Siming|Ye, Yiming|Huang, Yun|Gadda, Giovanni|Yang, Jenny J | ||||||||||
| PMID: | 19271729 | ||||||||||
| 15. | |||||||||||
| Journal: | Cancer Lett. 2009 Jan 18;273(2):266-72. | ||||||||||
| Title: | Cathepsin B is a target of Hedgehog signaling in pancreatic cancer. | ||||||||||
| Author: | Hwang, Jin-Hyeok|Lee, Sang Hyub|Lee, Kwang Hyuck|Lee, Keung Youp|Kim, Haeryoung|Ryu, Ji Kon|Yoon, Yong Bum|Kim, Yong-Tae | ||||||||||
| PMID: | 19004543 | ||||||||||
| 16. | |||||||||||
| Journal: | Gastroenterology. 2009 May;136(5):1772-82. | ||||||||||
| Title: | Heat shock protein 70 inhibits apoptosis in cancer cells through simultaneous and independent mechanisms. | ||||||||||
| Author: | Dudeja, Vikas|Mujumdar, Nameeta|Phillips, Phoebe|Chugh, Rohit|Borja-Cacho, Daniel|Dawra, Rajinder K|Vickers, Selwyn M|Saluja, Ashok K | ||||||||||
| PMID: | 19208367 | ||||||||||
| 17. | |||||||||||
| Journal: | Cancer Res. 2011 Nov 15;71(22):7091-102. | ||||||||||
| Title: | AGR2 is a novel surface antigen that promotes the dissemination of pancreatic cancer cells through regulation of cathepsins B and D. | ||||||||||
| Author: | Dumartin, Laurent|Whiteman, Hannah J|Weeks, Mark E|Hariharan, Deepak|Dmitrovic, Branko|Iacobuzio-Donahue, Christine A|Brentnall, Teresa A|Bronner, Mary P|Feakins, Roger M|Timms, John F|Brennan, Caroline|Lemoine, Nicholas R|Crnogorac-Jurcevic, Tatjana | ||||||||||
| PMID: | 21948970 | ||||||||||
| 18. | |||||||||||
| Journal: | Gut. 2012 Jun;61(6):877-84. | ||||||||||
| Title: | Cathepsin B promotes the progression of pancreatic ductal adenocarcinoma in mice. | ||||||||||
| Author: | Gopinathan, Aarthi|Denicola, Gina M|Frese, Kristopher K|Cook, Natalie|Karreth, Florian A|Mayerle, Julia|Lerch, Markus M|Reinheckel, Thomas|Tuveson, David A | ||||||||||
| PMID: | 22157328 | ||||||||||
| 19. | |||||||||||
| Journal: | Molecules. 2012 Mar 26;17(4):3672-89. | ||||||||||
| Title: | The feasibility of enzyme targeted activation for amino acid/dipeptide monoester prodrugs of floxuridine; cathepsin D as a potential targeted enzyme. | ||||||||||
| Author: | Tsume, Yasuhiro|Amidon, Gordon L | ||||||||||
| PMID: | 22450679 | ||||||||||
| 20. | |||||||||||
| Journal: | PLoS One. 2012;7(8):e43020. | ||||||||||
| Title: | MUC1c regulates cell survival in pancreatic cancer by preventing lysosomal permeabilization. | ||||||||||
| Author: | Banerjee, Sulagna|Mujumdar, Nameeta|Dudeja, Vikas|Mackenzie, Tiffany|Krosch, Tara K|Sangwan, Veena|Vickers, Selwyn M|Saluja, Ashok K | ||||||||||
| PMID: | 22912777 | ||||||||||
| 21. | |||||||||||
| Journal: | Bioconjug Chem. 2013 Jul 17;24(7):1161-73. | ||||||||||
| Title: | Self-assembling, amphiphilic polymer-gemcitabine conjugate shows enhanced antitumor efficacy against human pancreatic adenocarcinoma. | ||||||||||
| Author: | Chitkara, Deepak|Mittal, Anupama|Behrman, Stephan W|Kumar, Neeraj|Mahato, Ram I | ||||||||||
| PMID: | 23758084 | ||||||||||
| 22. | |||||||||||
| Journal: | Nucl Med Biol. 2013 Jul;40(5):606-17. | ||||||||||
| Title: | 177Lu-labeled HPMA copolymers utilizing cathepsin B and S cleavable linkers: synthesis, characterization and preliminary in vivo investigation in a pancreatic cancer model. | ||||||||||
| Author: | Ogbomo, Sunny M|Shi, Wen|Wagh, Nilesh K|Zhou, Zhengyuan|Brusnahan, Susan K|Garrison, Jered C | ||||||||||
| PMID: | 23622691 | ||||||||||
| 23. | |||||||||||
| Journal: | Mod Pathol. 2013 Jan;26(1):139-47. | ||||||||||
| Title: | Heterogeneity in signaling pathways of gastroenteropancreatic neuroendocrine tumors: a critical look at notch signaling pathway. | ||||||||||
| Author: | Wang, He|Chen, Yili|Fernandez-Del Castillo, Carlos|Yilmaz, Omer|Deshpande, Vikram | ||||||||||
| PMID: | 22918166 | ||||||||||
| 24. | |||||||||||
| Journal: | Bull Cancer. 2014 Jun;101(6):605-7. | ||||||||||
| Title: | [Impact of chemotherapies on immunosuppression and discovery of new therapeutic targets]. | ||||||||||
| Author: | Bruchard, Melanie|Ghiringhelli, Francois | ||||||||||
| PMID: | 24899072 | ||||||||||
| 25. | |||||||||||
| Journal: | Int J Cancer. 2015 Sep 15;137(6):1457-66. | ||||||||||
| Title: | Antitumor effect of antitissue factor antibody-MMAE conjugate in human pancreatic tumor xenografts. | ||||||||||
| Author: | Koga, Yoshikatsu|Manabe, Shino|Aihara, Yoshiyuki|Sato, Ryuta|Tsumura, Ryo|Iwafuji, Hikaru|Furuya, Fumiaki|Fuchigami, Hirobumi|Fujiwara, Yuki|Hisada, Yohei|Yamamoto, Yoshiyuki|Yasunaga, Masahiro|Matsumura, Yasuhiro | ||||||||||
| PMID: | 25704403 | ||||||||||
| 26. | |||||||||||
| Journal: | Colloids Surf B Biointerfaces. 2015 Apr 1;128:357-62. | ||||||||||
| Title: | Enhanced cellular uptake and intracellular drug controlled release of VESylated gemcitabine prodrug nanocapsules. | ||||||||||
| Author: | Fang, Yanfen|Du, Fang|Xu, Yanyun|Meng, Haijing|Huang, Jin|Zhang, Xiongwen|Lu, Wei|Liu, Shiyuan|Yu, Jiahui | ||||||||||
| PMID: | 25746328 | ||||||||||
| 27. | |||||||||||
| Journal: | ACS Nano. 2017 Feb 28;11(2):1281-1291. | ||||||||||
| Title: | Dual Enzymatic Reaction-Assisted Gemcitabine Delivery Systems for Programmed Pancreatic Cancer Therapy. | ||||||||||
| Author: | Han, Haijie|Valdeperez, Daniel|Jin, Qiao|Yang, Bin|Li, Zuhong|Wu, Yulian|Pelaz, Beatriz|Parak, Wolfgang J|Ji, Jian | ||||||||||
| PMID: | 28071891 | ||||||||||
| 28. | |||||||||||
| Journal: | Sci Rep. 2017 Jan 31;7:41862. | ||||||||||
| Title: | Lysosomal dysfunction and autophagy blockade contribute to IMB-6G-induced apoptosis in pancreatic cancer cells. | ||||||||||
| Author: | Liu, Lu|Zhang, Na|Dou, Yueying|Mao, Genxiang|Bi, Chongwen|Pang, Weiqiang|Liu, Xiaojia|Song, Danqing|Deng, Hongbin | ||||||||||
| PMID: | 28139733 | ||||||||||
| 29. | |||||||||||
| Journal: | J Colloid Interface Sci. 2017 Dec 1;507:217-224. | ||||||||||
| Title: | Enzyme-sensitive gemcitabine conjugated albumin nanoparticles as a versatile theranostic nanoplatform for pancreatic cancer treatment. | ||||||||||
| Author: | Han, Haijie|Wang, Jinhui|Chen, Tingting|Yin, Lichen|Jin, Qiao|Ji, Jian | ||||||||||
| PMID: | 28800445 | ||||||||||
| 30. | |||||||||||
| Journal: | Nanomedicine. 2018 Aug;14(6):1823-1832. | ||||||||||
| Title: | Early detection of pancreatic cancers in liquid biopsies by ultrasensitive fluorescence nanobiosensors. | ||||||||||
| Author: | Kalubowilage, Madumali|Covarrubias-Zambrano, Obdulia|Malalasekera, Aruni P|Wendel, Sebastian O|Wang, Hongwang|Yapa, Asanka S|Chlebanowski, Lauren|Toledo, Yubisela|Ortega, Raquel|Janik, Katharine E|Shrestha, Tej B|Culbertson, Christopher T|Kasi, Anup|Willi | ||||||||||
| PMID: | 29782949 | ||||||||||
| 31. | |||||||||||
| Journal: | Toxicol Appl Pharmacol. 2018 Oct 1;356:159-171. | ||||||||||
| Title: | Alantolactone induces apoptosis and improves chemosensitivity of pancreatic cancer cells by impairment of autophagy-lysosome pathway via targeting TFEB. | ||||||||||
| Author: | He, Ruizhi|Shi, Xiuhui|Zhou, Min|Zhao, Yan|Pan, Shutao|Zhao, Chunle|Guo, Xingjun|Wang, Min|Li, Xu|Qin, Renyi | ||||||||||
| PMID: | 30086361 | ||||||||||