Primary Site >> Liver Cancer

Gene >> CTNNB1

1.
Journal: Genes Chromosomes Cancer. 1999 Aug;25(4):399-402.
Title: Beta-catenin accumulation and mutation of the CTNNB1 gene in hepatoblastoma.
Author: Blaker, H|Hofmann, W J|Rieker, R J|Penzel, R|Graf, M|Otto, H F
PMID: 10398436
2.
Journal: Acta Gastroenterol Belg. 1999 Oct-Dec;62(4):393-402.
Title: The role of the E-cadherin/catenin complex in gastrointestinal cancer.
Author: Debruyne, P|Vermeulen, S|Mareel, M
PMID: 10692769
3.
Journal: Nat Genet. 2000 Mar;24(3):245-50.
Title: AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1.
Author: Satoh, S|Daigo, Y|Furukawa, Y|Kato, T|Miwa, N|Nishiwaki, T|Kawasoe, T|Ishiguro, H|Fujita, M|Tokino, T|Sasaki, Y|Imaoka, S|Murata, M|Shimano, T|Yamaoka, Y|Nakamura, Y
PMID: 10700176
4.
Journal: Oncogene. 2002 Nov 14;21(52):7971-80.
Title: P53 mutation as a source of aberrant beta-catenin accumulation in cancer cells.
Author: Cagatay, Tolga|Ozturk, Mehmet
PMID: 12439747
5.
Journal: Jpn J Cancer Res. 2002 Nov;93(11):1213-20.
Title: Analysis of the beta-catenin/T cell factor signaling pathway in 36 gastrointestinal and liver cancer cells.
Author: Ikenoue, Tsuneo|Ijichi, Hideaki|Kato, Naoya|Kanai, Fumihiko|Masaki, Tsutomu|Rengifo, William|Okamoto, Makoto|Matsumura, Masayuki|Kawabe, Takao|Shiratori, Yasushi|Omata, Masao
PMID: 12460462
6.
Journal: Digestion. 2002;66(3):131-44.
Title: Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis.
Author: Kolligs, Frank T|Bommer, Guido|Goke, Burkhard
PMID: 12481159
7.
Journal: J Biol Chem. 2003 Feb 14;278(7):5188-94.
Title: Identification of the LIM protein FHL2 as a coactivator of beta-catenin.
Author: Wei, Yu|Renard, Claire-Angelique|Labalette, Charlotte|Wu, Yuanfei|Levy, Laurence|Neuveut, Christine|Prieur, Xavier|Flajolet, Marc|Prigent, Sylvie|Buendia, Marie-Annick
PMID: 12466281
8.
Journal: J Clin Oncol. 2003 May 1;21(9):1708-14.
Title: Loss of beta-catenin expression in metastatic gastric cancer.
Author: Ebert, Matthias P A|Yu, Jun|Hoffmann, Juliane|Rocco, Alba|Rocken, Christoph|Kahmann, Sabine|Muller, Oliver|Korc, Murray|Sung, Joseph J|Malfertheiner, Peter
PMID: 12721245
9.
Journal: J Hepatol. 2004 Aug;41(2):292-8.
Title: Clinical and molecular analysis of combined hepatocellular-cholangiocarcinomas.
Author: Cazals-Hatem, Dominique|Rebouissou, Sandra|Bioulac-Sage, Paulette|Bluteau, Olivier|Blanche, Helene|Franco, Dominique|Monges, Genevieve|Belghiti, Jacques|Sa Cunha, Antonio|Laurent-Puig, Pierre|Degott, Claude|Zucman-Rossi, Jessica
PMID: 15288479
10.
Journal: Hepatology. 2005 Aug;42(2):353-61.
Title: Genotype-phenotype relationships in hepatocellular tumors from mice and man.
Author: Stahl, Sabine|Ittrich, Carina|Marx-Stoelting, Philip|Kohle, Christoph|Altug-Teber, Ozge|Riess, Olaf|Bonin, Michael|Jobst, Jurgen|Kaiser, Stephan|Buchmann, Albrecht|Schwarz, Michael
PMID: 15965925
11.
Journal: Oncol Rep. 2006 Mar;15(3):551-6.
Title: Diagnostic and prognostic impact of beta-catenin alterations in pediatric liver tumors.
Author: Yamaoka, Hiroaki|Ohtsu, Kazuhiro|Sueda, Taijiro|Yokoyama, Takashi|Hiyama, Eiso
PMID: 16465411
12.
Journal: Cancer Genet Cytogenet. 2006 Jul 15;168(2):158-61.
Title: APC and CTNNB1 mutations are rare in sporadic ependymomas.
Author: Onilude, Olabisi E|Lusher, Meryl E|Lindsey, Janet C|Pearson, Andrew D J|Ellison, David W|Clifford, Steven C
PMID: 16843107
13.
Journal: Genes Chromosomes Cancer. 2006 Nov;45(11):1050-7.
Title: Genetic inactivation of the APC gene contributes to the malignant progression of sporadic hepatocellular carcinoma: a case report.
Author: Katoh, Hiroto|Shibata, Tatsuhiro|Kokubu, Akiko|Ojima, Hidenori|Kosuge, Tomoo|Kanai, Yae|Hirohashi, Setsuo
PMID: 16897741
14.
Journal: Toxicology. 2006 Oct 3;227(1-2):127-35.
Title: Rex3 (reduced in expression 3) as a new tumor marker in mouse hepatocarcinogenesis.
Author: Braeuning, Albert|Jaworski, Maike|Schwarz, Michael|Kohle, Christoph
PMID: 16959394
15.
Journal: J Biol Chem. 2006 Nov 24;281(47):35598-602.
Title: Suppressing Wnt signaling by the hedgehog pathway through sFRP-1.
Author: He, Jing|Sheng, Tao|Stelter, Arwen A|Li, Chengxin|Zhang, Xiaoli|Sinha, Mala|Luxon, Bruce A|Xie, Jingwu
PMID: 17035233
16.
Journal: Mol Cancer Ther. 2006 Nov;5(11):2861-71.
Title: Targeting the active beta-catenin pathway to treat cancer cells.
Author: Dvory-Sobol, Hadas|Sagiv, Eyal|Kazanov, Diana|Ben-Ze'ev, Avri|Arber, Nadir
PMID: 17121933
17.
Journal: Dig Liver Dis. 2007 Jul;39(7):671-7.
Title: Genomic stability prevails in North-African hepatocellular carcinomas.
Author: Pineau, P|Ezzikouri, S|Marchio, A|Benazzouz, M|Cordina, E|Afifi, R|Elkihal, L|Khalfallah, M T|Mestiri, H|Tebbal, S|Berkane, S|Debzi, N|Triki, H|Dejean, A|Iguer, F|Bahri, O|Essaid El Feydi, A E E|Benjelloun, S
PMID: 17531558
18.
Journal: Carcinogenesis. 2007 Dec;28(12):2459-66. Epub 2007 Aug 3.
Title: Frequent epigenetic inactivation of DICKKOPF family genes in human gastrointestinal tumors.
Author: Sato, Hironobu|Suzuki, Hiromu|Toyota, Minoru|Nojima, Masanori|Maruyama, Reo|Sasaki, Shigeru|Takagi, Hideyasu|Sogabe, Yohei|Sasaki, Yasushi|Idogawa, Masashi|Sonoda, Tomoko|Mori, Mitsuru|Imai, Kohzoh|Tokino, Takashi|Shinomura, Yasuhisa
PMID: 17675336
19.
Journal: J Mol Diagn. 2007 Sep;9(4):510-20.
Title: Rapid identification of promoter hypermethylation in hepatocellular carcinoma by pyrosequencing of etiologically homogeneous sample pools.
Author: Dejeux, Emelyne|Audard, Virginie|Cavard, Catherine|Gut, Ivo Glynne|Terris, Benoit|Tost, Jorg
PMID: 17690210
20.
Journal: Proteomics. 2007 Sep;7(18):3318-31.
Title: Proteome analysis of chemically induced mouse liver tumors with different genotype.
Author: Strathmann, Julia|Paal, Krisztina|Ittrich, Carina|Krause, Eberhard|Appel, Klaus E|Glauert, Howard P|Buchmann, Albrecht|Schwarz, Michael
PMID: 17722141
21.
Journal: Neoplasia. 2007 Nov;9(11):951-9.
Title: siRNA-mediated beta-catenin knockdown in human hepatoma cells results in decreased growth and survival.
Author: Zeng, Gang|Apte, Udayan|Cieply, Benjamin|Singh, Sucha|Monga, Satdarshan P S
PMID: 18030363
22.
Journal: Mod Pathol. 2008 Jun;21(6):670-5.
Title: Epigenetic instability is rare in fibrolamellar carcinomas but common in viral-associated hepatocellular carcinomas.
Author: Vivekanandan, Perumal|Torbenson, Michael
PMID: 18264082
23.
Journal: Cancer Lett. 2008 Jun 18;264(2):201-8.
Title: Ser-249 TP53 and CTNNB1 mutations in circulating free DNA of Egyptian patients with hepatocellular carcinoma versus chronic liver diseases.
Author: Hosny, Gihan|Farahat, Nahla|Tayel, Hanan|Hainaut, Pierre
PMID: 18313840
24.
Journal: J Gastroenterol. 2008;43(5):378-89.
Title: Frequent epigenetic inactivation of SFRP genes in hepatocellular carcinoma.
Author: Takagi, Hideyasu|Sasaki, Shigeru|Suzuki, Hiromu|Toyota, Minoru|Maruyama, Reo|Nojima, Masanori|Yamamoto, Hiroyuki|Omata, Masao|Tokino, Takashi|Imai, Kohzoh|Shinomura, Yasuhisa
PMID: 18592156
25.
Journal: Cancer Res. 2008 Aug 15;68(16):6779-88.
Title: Focal gains of VEGFA and molecular classification of hepatocellular carcinoma.
Author: Chiang, Derek Y|Villanueva, Augusto|Hoshida, Yujin|Peix, Judit|Newell, Philippa|Minguez, Beatriz|LeBlanc, Amanda C|Donovan, Diana J|Thung, Swan N|Sole, Manel|Tovar, Victoria|Alsinet, Clara|Ramos, Alex H|Barretina, Jordi|Roayaie, Sasan|Schwartz, Myron|Waxm
PMID: 18701503
26.
Journal: Int J Cancer. 2008 Dec 15;123(12):2735-40.
Title: Organ-specific profiles of genetic changes in cancers caused by activation-induced cytidine deaminase expression.
Author: Morisawa, Toshiyuki|Marusawa, Hiroyuki|Ueda, Yoshihide|Iwai, Akio|Okazaki, Il-mi|Honjo, Tasuku|Chiba, Tsutomu
PMID: 18781563
27.
Journal: Hepatology. 2009 Mar;49(3):821-31.
Title: Unique phenotype of hepatocellular cancers with exon-3 mutations in beta-catenin gene.
Author: Cieply, Benjamin|Zeng, Gang|Proverbs-Singh, Tracy|Geller, David A|Monga, Satdarshan P S
PMID: 19101982
28.
Journal: Transl Oncol. 2009 Aug 18;2(3):157-63.
Title: Altered microRNA Expression Patterns in Hepatoblastoma Patients.
Author: Magrelli, Armando|Azzalin, Gianluca|Salvatore, Marco|Viganotti, Mara|Tosto, Fabrizio|Colombo, Teresa|Devito, Rita|Di Masi, Alessandra|Antoccia, Antonio|Lorenzetti, Stefano|Maranghi, Francesca|Mantovani, Alberto|Tanzarella, Caterina|Macino, Giuseppe|Tarusc
PMID: 19701500
29.
Journal: J Cell Mol Med. 2010 Mar;14(3):621-35.
Title: URG11 promotes gastric cancer growth and invasion by activation of beta-catenin signalling pathway.
Author: Du, Rui|Xia, Lin|Sun, Shiren|Lian, Zhaorui|Zou, Xue|Gao, Juan|Xie, Huahong|Fan, Rui|Song, Jiugang|Li, Xiaohua|Liu, Jie|Fan, Daiming
PMID: 19413886
30.
Journal: J Hepatol. 2010 May;52(5):771-5.
Title: Personalized molecular targeted therapy in advanced, recurrent hepatocellular carcinoma after liver transplantation: a proof of principle.
Author: Bhoori, Sherrie|Toffanin, Sara|Sposito, Carlo|Germini, Alessandro|Pellegrinelli, Alessandro|Lampis, Andrea|Mazzaferro, Vincenzo
PMID: 20347502
31.
Journal: BMC Cancer. 2010 Oct 6;10:530.
Title: Genetic and epigenetic characteristics of human multiple hepatocellular carcinoma.
Author: Taniguchi, Kazuya|Yamada, Terumasa|Sasaki, Yo|Kato, Kikuya
PMID: 20923573
32.
Journal: Cell Mol Biol (Noisy-le-grand). 2010 Jun 10;56 Suppl:OL1299-317.
Title: Characterization of HuH6, Hep3B, HepG2 and HLE liver cancer cell lines by WNT/beta - catenin pathway, microRNA expression and protein expression profile.
Author: Di Masi, A|Viganotti, M|Antoccia, A|Magrelli, A|Salvatore, M|Azzalin, G|Tosto, F|Lorenzetti, S|Maranghi, F|Mantovani, A|Macino, G|Tanzarella, C|Taruscio, D
PMID: 20937217
33.
Journal: J Gastrointest Cancer. 2011 Mar;42(1):20-5.
Title: Hepatitis B virus-associated hepatocellular carcinoma from India: role of viral genotype and mutations in CTNNB1 (beta-catenin) and TP53 genes.
Author: Vivekanandan, Perumal|Torbenson, Michael|Ramakrishna, Banumathi
PMID: 20963515
34.
Journal: Carcinogenesis. 2011 Jan;32(1):52-7.
Title: Tumor formation in liver of conditional beta-catenin-deficient mice exposed to a diethylnitrosamine/phenobarbital tumor promotion regimen.
Author: Rignall, Benjamin|Braeuning, Albert|Buchmann, Albrecht|Schwarz, Michael
PMID: 21047994
35.
Journal: Gastroenterology. 2011 May;140(5):1618-28.e16.
Title: MicroRNA-based classification of hepatocellular carcinoma and oncogenic role of miR-517a.
Author: Toffanin, Sara|Hoshida, Yujin|Lachenmayer, Anja|Villanueva, Augusto|Cabellos, Laia|Minguez, Beatriz|Savic, Radoslav|Ward, Stephen C|Thung, Swan|Chiang, Derek Y|Alsinet, Clara|Tovar, Victoria|Roayaie, Sasan|Schwartz, Myron|Bruix, Jordi|Waxman, Samuel|Fried
PMID: 21324318
36.
Journal: Radiology. 2011 Mar;258(3):673-93.
Title: Recent advances in cytogenetics and molecular biology of adult hepatocellular tumors: implications for imaging and management.
Author: Shanbhogue, Alampady K|Prasad, Srinivasa R|Takahashi, Naoki|Vikram, Raghunandan|Sahani, Dushyant V
PMID: 21339346
37.
Journal: Cancer Sci. 2011 Sep;102(9):1742-7.
Title: Expression of SLCO1B3 is associated with intratumoral cholestasis and CTNNB1 mutations in hepatocellular carcinoma.
Author: Sekine, Shigeki|Ogawa, Reiko|Ojima, Hidenori|Kanai, Yae
PMID: 21615622
38.
Journal: Hepat Res Treat. 2011;2011:697162.
Title: Mutations in TP53 and CTNNB1 in Relation to Hepatitis B and C Infections in Hepatocellular Carcinomas from Thailand.
Author: Galy, Olivier|Chemin, Isabelle|Le Roux, Emilie|Villar, Stephanie|Le Calvez-Kelm, Florence|Lereau, Myriam|Gouas, Doriane|Vieco, Beatriz|Suarez, Iris|Navas, Maria-Cristina|Chevallier, Michele|Norder, Helene|Srivatanakul, Petcharin|Karalak, Anant|Sangrajrang
PMID: 21760996
39.
Journal: J Mol Histol. 2011 Oct;42(5):393-400.
Title: Phenotype of single hepatocytes expressing an activated version of beta-catenin in liver of transgenic mice.
Author: Schreiber, Sandra|Rignall, Benjamin|Braeuning, Albert|Marx-Stoelting, Philip|Ott, Thomas|Buchmann, Albrecht|Hammad, Seddik|Hengstler, Jan G|Schwarz, Michael|Kohle, Christoph
PMID: 21822615
40.
Journal: Curr Genomics. 2011 Apr;12(2):130-7.
Title: Genetic and epigenetic signatures in human hepatocellular carcinoma: a systematic review.
Author: Nishida, Naoshi|Goel, Ajay
PMID: 21966251
41.
Journal: J Exp Clin Cancer Res. 2011 Oct 12;30:96.
Title: HGF/c-Met related activation of beta-catenin in hepatoblastoma.
Author: Purcell, Rachel|Childs, Margaret|Maibach, Rudolf|Miles, Carina|Turner, Clinton|Zimmermann, Arthur|Sullivan, Michael
PMID: 21992464
42.
Journal: Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18384-9.
Title: Depletion of beta-catenin from mature hepatocytes of mice promotes expansion of hepatic progenitor cells and tumor development.
Author: Wang, Er-Yea|Yeh, Shiou-Hwei|Tsai, Ting-Fen|Huang, Hsiang-Po|Jeng, Yung-Ming|Lin, Wei-Hsiang|Chen, Wei-Chih|Yeh, Kun-Huei|Chen, Pei-Jer|Chen, Ding-Shinn
PMID: 22042854
43.
Journal: J Hepatol. 2012 Jan;56(1):184-91.
Title: GNAS-activating mutations define a rare subgroup of inflammatory liver tumors characterized by STAT3 activation.
Author: Nault, Jean Charles|Fabre, Monique|Couchy, Gabrielle|Pilati, Camilla|Jeannot, Emmanuelle|Tran Van Nhieu, Jeanne|Saint-Paul, Marie-Christine|De Muret, Anne|Redon, Marie-Jose|Buffet, Catherine|Salenave, Sylvie|Balabaud, Charles|Prevot, Sophie|Labrune, Phili
PMID: 21835143
44.
Journal: Hepatology. 2012 Jun;55(6):1830-9.
Title: Zinc finger transcription factor 191, directly binding to beta-catenin promoter, promotes cell proliferation of hepatocellular carcinoma.
Author: Liu, Guoyuan|Jiang, Songmin|Wang, Chenji|Jiang, Wei|Liu, Zulong|Liu, Chao|Saiyin, Hexige|Yang, Xianmei|Shen, Suqin|Jiang, Deke|Zhou, Ping|Han, Dingding|Hu, Xiaohui|Yi, Qing|Yu, Long
PMID: 22213192
45.
Journal: Ann Surg Oncol. 2012 Aug;19(8):2643-51.
Title: Resection of adrenocortical carcinoma liver metastasis: is it justified?
Author: Gaujoux, Sebastien|Al-Ahmadie, Hikmat|Allen, Peter J|Gonen, Mithat|Shia, Jinru|D'Angelica, Michael|Dematteo, Ronald|Fong, Yuman|Blumgart, Leslie|Jarnagin, William R
PMID: 22526905
46.
Journal: Nat Genet. 2012 May 6;44(6):694-8.
Title: Integrated analysis of somatic mutations and focal copy-number changes identifies key genes and pathways in hepatocellular carcinoma.
Author: Guichard, Cecile|Amaddeo, Giuliana|Imbeaud, Sandrine|Ladeiro, Yannick|Pelletier, Laura|Maad, Ichrafe Ben|Calderaro, Julien|Bioulac-Sage, Paulette|Letexier, Melanie|Degos, Francoise|Clement, Bruno|Balabaud, Charles|Chevet, Eric|Laurent, Alexis|Couchy, Gabr
PMID: 22561517
47.
Journal: Clin Cancer Res. 2012 Sep 15;18(18):4997-5007.
Title: Wnt-pathway activation in two molecular classes of hepatocellular carcinoma and experimental modulation by sorafenib.
Author: Lachenmayer, Anja|Alsinet, Clara|Savic, Radoslav|Cabellos, Laia|Toffanin, Sara|Hoshida, Yujin|Villanueva, Augusto|Minguez, Beatriz|Newell, Philippa|Tsai, Hung-Wen|Barretina, Jordi|Thung, Swan|Ward, Stephen C|Bruix, Jordi|Mazzaferro, Vincenzo|Schwartz, Myr
PMID: 22811581
48.
Journal: PLoS One. 2012;7(9):e44206.
Title: MiR-214 targets beta-catenin pathway to suppress invasion, stem-like traits and recurrence of human hepatocellular carcinoma.
Author: Xia, Hongping|Ooi, London Lucien P J|Hui, Kam M
PMID: 22962603
49.
Journal: Scientifica (Cairo). 2012;2012:743790.
Title: Fibrolamellar carcinoma: 2012 update.
Author: Torbenson, Michael
PMID: 24278737
50.
Journal: J Hepatol. 2013 Feb;58(2):350-7.
Title: Molecular characterization of hepatocellular adenomas developed in patients with glycogen storage disease type I.
Author: Calderaro, Julien|Labrune, Philippe|Morcrette, Guillaume|Rebouissou, Sandra|Franco, Dominique|Prevot, Sophie|Quaglia, Alberto|Bedossa, Pierre|Libbrecht, Louis|Terracciano, Luigi|Smit, G Peter A|Bioulac-Sage, Paulette|Zucman-Rossi, Jessica
PMID: 23046672
51.
Journal: Toxicol Pathol. 2013 Aug;41(6):826-41.
Title: Hepatocellular carcinomas in B6C3F1 mice treated with Ginkgo biloba extract for two years differ from spontaneous liver tumors in cancer gene mutations and genomic pathways.
Author: Hoenerhoff, Mark J|Pandiri, Arun R|Snyder, Stephanie A|Hong, Hue-Hua L|Ton, Thai-Vu|Peddada, Shyamal|Shockley, Keith|Witt, Kristine|Chan, Po|Rider, Cynthia|Kooistra, Linda|Nyska, Abraham|Sills, Robert C
PMID: 23262642
52.
Journal: N Biotechnol. 2013 May 25;30(4):381-4.
Title: Genetics and epigenetics of liver cancer.
Author: Ozen, Cigdem|Yildiz, Gokhan|Dagcan, Alper Tunga|Cevik, Dilek|Ors, Aysegul|Keles, Umur|Topel, Hande|Ozturk, Mehmet
PMID: 23392071
53.
Journal: Int J Hepatol. 2013;2013:315947.
Title: Molecular classification of hepatocellular adenomas.
Author: Nault, Jean Charles|Zucman Rossi, Jessica
PMID: 23401783
54.
Journal: Oncology. 2013;84 Suppl 1:93-7.
Title: Recent advancements in comprehensive genetic analyses for human hepatocellular carcinoma.
Author: Nishida, Naoshi|Kudo, Masatoshi
PMID: 23428866
55.
Journal: Hepatology. 2013 Jul;58(1):229-38.
Title: Tissue metabolomics of hepatocellular carcinoma: tumor energy metabolism and the role of transcriptomic classification.
Author: Beyoglu, Diren|Imbeaud, Sandrine|Maurhofer, Olivier|Bioulac-Sage, Paulette|Zucman-Rossi, Jessica|Dufour, Jean-Francois|Idle, Jeffrey R
PMID: 23463346
56.
Journal: Arch Toxicol. 2013 Aug;87(8):1595-607.
Title: Selective poisoning of Ctnnb1-mutated hepatoma cells in mouse liver tumors by a single application of acetaminophen.
Author: Singh, Yasmin|Braeuning, Albert|Schmid, Andreas|Pichler, Bernd J|Schwarz, Michael
PMID: 23479080
57.
Journal: Genomics. 2013 Aug;102(2):74-83.
Title: Mutations in TP53, CTNNB1 and PIK3CA genes in hepatocellular carcinoma associated with hepatitis B and hepatitis C virus infections.
Author: Tornesello, Maria Lina|Buonaguro, Luigi|Tatangelo, Fabiana|Botti, Gerardo|Izzo, Francesco|Buonaguro, Franco M
PMID: 23583669
58.
Journal: Environ Sci Pollut Res Int. 2013 Sep;20(9):6468-81.
Title: Signal transduction disturbance related to hepatocarcinogenesis in mouse by prolonged exposure to Nanjing drinking water.
Author: Zhang, Rui|Sun, Jie|Zhang, Yan|Cheng, Shupei|Zhang, Xiaowei
PMID: 23591932
59.
Journal: Hepatology. 2013 Nov;58(5):1693-702.
Title: Identification of driver genes in hepatocellular carcinoma by exome sequencing.
Author: Cleary, Sean P|Jeck, William R|Zhao, Xiaobei|Chen, Kui|Selitsky, Sara R|Savich, Gleb L|Tan, Ting-Xu|Wu, Michael C|Getz, Gad|Lawrence, Michael S|Parker, Joel S|Li, Jinyu|Powers, Scott|Kim, Hyeja|Fischer, Sandra|Guindi, Maha|Ghanekar, Anand|Chiang, Derek Y
PMID: 23728943
60.
Journal: Mutat Res. 2013 Aug 15;755(2):90-9.
Title: Somatic changes in primary liver cancer in Russia: a pilot study.
Author: Kalinina, Olga|Marchio, Agnes|Urbanskii, Aleksandr I|Tarkova, Aleksandra B|Rebbani, Khadija|Granov, Dmitri A|Dejean, Anne|Generalov, Mikhail I|Pineau, Pascal
PMID: 23830926
61.
Journal: Nat Commun. 2013;4:2218.
Title: High frequency of telomerase reverse-transcriptase promoter somatic mutations in hepatocellular carcinoma and preneoplastic lesions.
Author: Nault, Jean Charles|Mallet, Maxime|Pilati, Camilla|Calderaro, Julien|Bioulac-Sage, Paulette|Laurent, Christophe|Laurent, Alexis|Cherqui, Daniel|Balabaud, Charles|Zucman-Rossi, Jessica
PMID: 23887712
62.
Journal: PLoS One. 2013 Nov 15;8(11):e79409.
Title: Downregulation of miR-200a induces EMT phenotypes and CSC-like signatures through targeting the beta-catenin pathway in hepatic oval cells.
Author: Liu, Jie|Ruan, Bai|You, Nan|Huang, Qike|Liu, Weihui|Dang, Zheng|Xu, Weihua|Zhou, Ti|Ji, Ru|Cao, Yang|Li, Xia|Wang, Desheng|Tao, Kaishan|Dou, Kefeng
PMID: 24260215
63.
Journal: World J Gastroenterol. 2013 Dec 21;19(47):8873-9.
Title: Target genes discovery through copy number alteration analysis in human hepatocellular carcinoma.
Author: Gu, De-Leung|Chen, Yen-Hsieh|Shih, Jou-Ho|Lin, Chi-Hung|Jou, Yuh-Shan|Chen, Chian-Feng
PMID: 24379610
64.
Journal: Int J Cancer. 2014 Jun 15;134(12):2778-88.
Title: Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice.
Author: Chappell, Grace|Kutanzi, Kristy|Uehara, Takeki|Tryndyak, Volodymyr|Hong, Hue-Hua|Hoenerhoff, Mark|Beland, Frederick A|Rusyn, Ivan|Pogribny, Igor P
PMID: 24242335
65.
Journal: Virchows Arch. 2014 Jan;464(1):53-60.
Title: ALDH3A1 is overexpressed in a subset of hepatocellular carcinoma characterised by activation of the Wnt/ss-catenin pathway.
Author: Calderaro, Julien|Nault, Jean-Charles|Bioulac-Sage, Paulette|Laurent, Alexis|Blanc, Jean-Frederic|Decaens, Thomas|Zucman-Rossi, Jessica
PMID: 24276407
66.
Journal: Int J Cancer. 2014 Oct 1;135(7):1574-85.
Title: Ha-ras and beta-catenin oncoproteins orchestrate metabolic programs in mouse liver tumors.
Author: Unterberger, Elif B|Eichner, Johannes|Wrzodek, Clemens|Lempiainen, Harri|Luisier, Raphaelle|Terranova, Remi|Metzger, Ute|Plummer, Simon|Knorpp, Thomas|Braeuning, Albert|Moggs, Jonathan|Templin, Markus F|Honndorf, Valerie|Piotto, Martial|Zell, Andreas|Schw
PMID: 24535843
67.
Journal: Clin Cancer Res. 2014 Apr 15;20(8):2072-9.
Title: Hepatocellular carcinoma: reasons for phase III failure and novel perspectives on trial design.
Author: Llovet, Josep M|Hernandez-Gea, Virginia
PMID: 24589894
68.
Journal: Cancer Genomics Proteomics. 2014 Jan-Feb;11(1):1-12.
Title: Genome-wide transcriptional sequencing identifies novel mutations in metabolic genes in human hepatocellular carcinoma.
Author: Meerzaman, Daoud M|Yan, Chunhua|Chen, Qing-Rong|Edmonson, Michael N|Schaefer, Carl F|Clifford, Robert J|Dunn, Barbara K|Dong, Li|Finney, Richard P|Cultraro, Constance M|Hu, Ying|Yang, Zhihui|Nguyen, Cu V|Kelley, Jenny M|Cai, Shuang|Zhang, Hongen|Zhang, Ji
PMID: 24633315
69.
Journal: Hepatology. 2014 Dec;60(6):1972-82.
Title: Genomic portrait of resectable hepatocellular carcinomas: implications of RB1 and FGF19 aberrations for patient stratification.
Author: Ahn, Sung-Min|Jang, Se Jin|Shim, Ju Hyun|Kim, Deokhoon|Hong, Seung-Mo|Sung, Chang Ohk|Baek, Daehyun|Haq, Farhan|Ansari, Adnan Ahmad|Lee, Sun Young|Chun, Sung-Min|Choi, Seongmin|Choi, Hyun-Jeung|Kim, Jongkyu|Kim, Sukjun|Hwang, Shin|Lee, Young-Joo|Lee, Jong
PMID: 24798001
70.
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Title: Transcriptomic characterization of hepatocellular carcinoma with CTNNB1 mutation.
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Journal: Am J Pathol. 2014 Jul;184(7):2111-22.
Title: Identification and characterization of a novel small-molecule inhibitor of beta-catenin signaling.
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Journal: Cancer Res. 2014 Aug 15;74(16):4515-25.
Title: beta-catenin activation in a novel liver progenitor cell type is sufficient to cause hepatocellular carcinoma and hepatoblastoma.
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Journal: Br J Cancer. 2014 Jul 8;111(1):132-8.
Title: Genetic ablation of beta-catenin inhibits the proliferative phenotype of mouse liver adenomas.
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Journal: PLoS One. 2014 Jun 3;9(6):e98817.
Title: Role of leukocyte cell-derived chemotaxin 2 as a biomarker in hepatocellular carcinoma.
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Journal: Hepatology. 2014 Nov;60(5):1686-96.
Title: Exome sequencing of hepatoblastoma reveals novel mutations and cancer genes in the Wnt pathway and ubiquitin ligase complex.
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Journal: Oncotarget. 2014 May 30;5(10):3012-22.
Title: Identification of novel therapeutic targets in the PI3K/AKT/mTOR pathway in hepatocellular carcinoma using targeted next generation sequencing.
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Journal: PLoS One. 2014 Jul 2;9(7):e100854.
Title: Integrated analysis of mutation data from various sources identifies key genes and signaling pathways in hepatocellular carcinoma.
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Journal: Oncology. 2014;87(3):159-66.
Title: beta-catenin (CTNNB1) mutations are not associated with prognosis in advanced hepatocellular carcinoma.
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Journal: J Hepatol. 2014 Nov;61(5):1178-83.
Title: Paediatric hepatocellular carcinoma due to somatic CTNNB1 and NFE2L2 mutations in the setting of inherited bi-allelic ABCB11 mutations.
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Journal: Cancer Res. 2014 Sep 15;74(18):5311-21.
Title: TALEN-mediated somatic mutagenesis in murine models of cancer.
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Journal: Br J Cancer. 2014 Sep 9;111(6):1159-67.
Title: Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts.
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Journal: J Hepatol. 2014 Dec;61(6):1312-20.
Title: The genomic landscape of hepatoblastoma and their progenies with HCC-like features.
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Journal: Genome Biol. 2014 Aug 26;15(8):436.
Title: Diverse modes of genomic alteration in hepatocellular carcinoma.
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Journal: Oncotarget. 2014 Sep 15;5(17):7663-76.
Title: CLDN3 inhibits cancer aggressiveness via Wnt-EMT signaling and is a potential prognostic biomarker for hepatocellular carcinoma.
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Journal: PLoS One. 2014 Dec 11;9(12):e114912.
Title: A peculiar mutation spectrum emerging from young peruvian patients with hepatocellular carcinoma.
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Journal: PLoS One. 2014 Dec 18;9(12):e115152.
Title: Profiling of exome mutations associated with progression of HBV-related hepatocellular carcinoma.
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Journal: Gut. 2015 May;64(5):820-9.
Title: Integration of tumour and viral genomic characterizations in HBV-related hepatocellular carcinomas.
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Journal: Clin Cancer Res. 2015 Apr 15;21(8):1951-61.
Title: Intratumor heterogeneity in hepatocellular carcinoma.
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Journal: Gastroenterology. 2015 Feb;148(2):415-26.e18.
Title: The long intergenic noncoding RNA UFC1, a target of MicroRNA 34a, interacts with the mRNA stabilizing protein HuR to increase levels of beta-catenin in HCC cells.
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Journal: J Hepatol. 2015 Feb;62(2):380-7.
Title: Complete response of Ctnnb1-mutated tumours to beta-catenin suppression by locked nucleic acid antisense in a mouse hepatocarcinogenesis model.
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Journal: Ann Hepatol. 2015 Jan-Feb;14(1):64-74.
Title: Wnt/beta-catenin signaling pathway in hepatocellular carcinomas cases from Colombia.
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Journal: Gastroenterology. 2015 Jun;148(7):1294-310.
Title: beta-Catenin Signaling and Roles in Liver Homeostasis, Injury, and Tumorigenesis.
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Journal: Cell Rep. 2015 Mar 10. pii: S2211-1247(15)00173-4.
Title: YAP Inhibition Restores Hepatocyte Differentiation in Advanced HCC, Leading to Tumor Regression.
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Journal: Hepatology. 2015 Sep;62(3):851-62.
Title: Nrf2, but not beta-catenin, mutation represents an early event in rat hepatocarcinogenesis.
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Journal: Cancer Lett. 2015 Jun 28;362(1):97-105.
Title: Wnt/beta-Catenin activates MiR-183/96/182 expression in hepatocellular carcinoma that promotes cell invasion.
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Journal: Nat Genet. 2015 May;47(5):505-511.
Title: Exome sequencing of hepatocellular carcinomas identifies new mutational signatures and potential therapeutic targets.
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Journal: PLoS One. 2015 Apr 22;10(4):e0123175.
Title: Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma.
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Journal: Pol J Pathol. 2015 Mar;66(1):9-21.
Title: Alterations of Wnt/beta-catenin signaling pathway in hepatocellular carcinomas associated with hepatitis C virus.
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Journal: World J Gastroenterol. 2015 May 28;21(20):6317-28.
Title: Integrative analysis of aberrant Wnt signaling in hepatitis B virus-related hepatocellular carcinoma.
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Journal: Oncotarget. 2015 Aug 28;6(25):21636-44.
Title: Targeted DNA and RNA sequencing of fine-needle biopsy FFPE specimens in patients with unresectable hepatocellular carcinoma treated with sorafenib.
Author: Sakai, Kazuko|Takeda, Haruhiko|Nishijima, Norihiro|Orito, Etsuro|Joko, Kouji|Uchida, Yasushi|Izumi, Namiki|Nishio, Kazuto|Osaki, Yukio
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Journal: Gastroenterology. 2015 Oct;149(5):1226-1239.e4.
Title: Genetic Landscape and Biomarkers of Hepatocellular Carcinoma.
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Journal: Clin Res Hepatol Gastroenterol. 2015 Sep;39 Suppl 1:S80-5.
Title: New molecular therapies for hepatocellular carcinoma.
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Journal: EMBO J. 2015 Sep 14;34(18):2321-33.
Title: E-cadherin can limit the transforming properties of activating beta-catenin mutations.
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Journal: Hepat Oncol. 2015;2(1):79-93.
Title: Liver cancer oncogenomics: opportunities and dilemmas for clinical applications.
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Journal: Hum Pathol. 2015 Jul;46(7):1068-77.
Title: ARID2, p110alpha, p53, and beta-catenin protein expression in hepatocellular carcinoma and clinicopathologic implications.
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Journal: Toxicol Pathol. 2015 Dec;43(8):1114-26.
Title: Genomic Profiling Reveals Unique Molecular Alterations in Hepatoblastomas and Adjacent Hepatocellular Carcinomas in B6C3F1 Mice.
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Journal: Virchows Arch. 2015 Nov;467(5):535-42.
Title: beta-catenin alteration is rare in hepatocellular carcinoma with steatohepatitic features: immunohistochemical and mutational study.
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Journal: Cancer Genet. 2015 Oct;208(10):513-6.
Title: Evaluation of CTNNB1 and TP53 variability in patients with hepatocellular carcinoma and occult hepatitis B virus infection.
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Journal: Oncotarget. 2015 Nov 24;6(37):39865-76.
Title: Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations.
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Journal: Semin Liver Dis. 2015 Nov;35(4):444-9.
Title: Hepatocellular Carcinoma Arising in an HNF-1alpha-Mutated Adenoma in a 23-Year-Old Woman with Maturity-Onset Diabetes of the Young: A Case Report.
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Journal: BMC Cancer. 2015 Dec 29;15:1020.
Title: A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1.
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Journal: J Appl Toxicol. 2016 Jan;36(1):105-12.
Title: Augmenting effects of gestational arsenite exposure of C3H mice on the hepatic tumors of the F(2) male offspring via the F(1) male offspring.
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Journal: Hepatology. 2016 Feb;63(2):499-511.
Title: Long noncoding RNA DANCR increases stemness features of hepatocellular carcinoma by derepression of CTNNB1.
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Journal: Clin Res Hepatol Gastroenterol. 2016 Feb;40(1):9-14.
Title: TERT promoter mutations in primary liver tumors.
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Journal: J Gastroenterol. 2016 May;51(5):473-86.
Title: Comprehensive analyses of mutations and hepatitis B virus integration in hepatocellular carcinoma with clinicopathological features.
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Journal: J Surg Oncol. 2016 Jan;113(1):55-61.
Title: Comprehensive multiplatform biomarker analysis of 350 hepatocellular carcinomas identifies potential novel therapeutic options.
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Journal: Hepatol Res. 2016 Oct;46(11):1145-1151.
Title: Targeted and exome sequencing identified somatic mutations in hepatocellular carcinoma.
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Journal: Sci Rep. 2016 Feb 26;6:22090.
Title: PS341 inhibits hepatocellular and colorectal cancer cells through the FOXO3/CTNNB1 signaling pathway.
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Journal: Tumour Biol. 2016 Aug;37(8):11219-24.
Title: Armc8 regulates the invasive ability of hepatocellular carcinoma through E-cadherin/catenin complex.
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Journal: Clin Biochem. 2016 Jul;49(10-11):792-801.
Title: Genetic polymorphisms in the Wnt/beta-catenin pathway genes as predictors of tumor development and survival in patients with hepatitis B virus-associated hepatocellular carcinoma.
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Journal: Hepatology. 2016 Nov;64(5):1587-1605.
Title: Modeling a human hepatocellular carcinoma subset in mice through coexpression of met and point-mutant beta-catenin.
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Journal: PLoS One. 2016 Apr 21;11(4):e0152695.
Title: Diverse Basis of beta-Catenin Activation in Human Hepatocellular Carcinoma: Implications in Biology and Prognosis.
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Journal: Oncotarget. 2016 Jun 28;7(26):40481-40490.
Title: Noninvasive detection of tumor-associated mutations from circulating cell-free DNA in hepatocellular carcinoma patients by targeted deep sequencing.
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Journal: BMC Clin Pathol. 2016 Jun 1;16:7.
Title: Liver cancer with concomitant TP53 and CTNNB1 mutations: a case report.
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Journal: Oncotarget. 2016 Aug 23;7(34):54253-54262.
Title: Tumor specific mutations in TERT promoter and CTNNB1 gene in hepatitis B and hepatitis C related hepatocellular carcinoma.
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Journal: Mol Cancer Ther. 2016 Sep;15(9):2143-54.
Title: Direct Pharmacological Inhibition of beta-Catenin by RNA Interference in Tumors of Diverse Origin.
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Journal: Mod Pathol. 2016 Nov;29(11):1370-1380.
Title: Correlation of exon 3 beta-catenin mutations with glutamine synthetase staining patterns in hepatocellular adenoma and hepatocellular carcinoma.
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Journal: Int J Cancer. 2016 Dec 1;139(11):2512-8.
Title: TERT promoter mutations and chromosome 8p loss are characteristic of nonalcoholic fatty liver disease-related hepatocellular carcinoma.
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Journal: Cancers (Basel). 2016 Aug 20;8(8). pii: cancers8080076.
Title: Epigenetic Activation of Wnt/beta-Catenin Signaling in NAFLD-Associated Hepatocarcinogenesis.
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Journal: Oncotarget. 2016 Oct 25;7(43):69267-69275.
Title: Frequent somatic TERT promoter mutations and CTNNB1 mutations in hepatocellular carcinoma.
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Journal: J Cancer. 2016 Sep 13;7(13):1907-1914.
Title: Detecting Circulating Tumor DNA in Hepatocellular Carcinoma Patients Using Droplet Digital PCR Is Feasible and Reflects Intratumoral Heterogeneity.
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Journal: Oncotarget. 2016 Nov 15;7(46):75038-75051.
Title: miR-885-5p suppresses hepatocellular carcinoma metastasis and inhibits Wnt/beta-catenin signaling pathway.
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Journal: PLoS One. 2016 Nov 2;11(11):e0165457.
Title: Integrated Multiple "-omics" Data Reveal Subtypes of Hepatocellular Carcinoma.
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Journal: Neoplasia. 2016 Dec;18(12):711-723.
Title: Blocking Wnt Secretion Reduces Growth of Hepatocellular Carcinoma Cell Lines Mostly Independent of beta-Catenin Signaling.
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Journal: Exp Mol Med. 2016 Dec 2;48(12):e275.
Title: C-terminal-truncated HBV X promotes hepato-oncogenesis through inhibition of tumor-suppressive beta-catenin/BAMBI signaling.
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Journal: Gut. 2017 Jul;66(7):1268-1277.
Title: Wnt signalling modulates transcribed-ultraconserved regions in hepatobiliary cancers.
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Journal: Carcinogenesis. 2017 Jan;38(1):2-11.
Title: Frequently mutated genes/pathways and genomic instability as prevention targets in liver cancer.
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Journal: Gastroenterology. 2017 Mar;152(4):880-894.e6.
Title: Molecular Classification of Hepatocellular Adenoma Associates With Risk Factors, Bleeding, and Malignant Transformation.
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Journal: Hepatology. 2017 May;65(5):1581-1599.
Title: Targeting beta-catenin in hepatocellular cancers induced by coexpression of mutant beta-catenin and K-Ras in mice.
Author: Tao, Junyan|Zhang, Rong|Singh, Sucha|Poddar, Minakshi|Xu, Emily|Oertel, Michael|Chen, Xin|Ganesh, Shanthi|Abrams, Marc|Monga, Satdarshan P
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Journal: Hum Pathol. 2017 Apr;62:122-125.
Title: Malignant transformation of a beta-catenin inflammatory adenoma due to an S45 beta-catenin-activating mutation present 12 years before.
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Journal: J Hepatol. 2017 Apr;66(4):734-742.
Title: Germline and somatic DICER1 mutations in familial and sporadic liver tumors.
Author: Caruso, Stefano|Calderaro, Julien|Letouze, Eric|Nault, Jean-Charles|Couchy, Gabrielle|Boulai, Anais|Luciani, Alain|Zafrani, Elie-Serge|Bioulac-Sage, Paulette|Seror, Olivier|Imbeaud, Sandrine|Zucman-Rossi, Jessica
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Journal: J Vasc Interv Radiol. 2017 Mar;28(3):349-355.e1.
Title: Gene Signature Associated with Upregulation of the Wnt/beta-Catenin Signaling Pathway Predicts Tumor Response to Transarterial Embolization.
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Journal: Liver Int. 2017 Nov;37(11):1591-1601.
Title: Constitutional and functional genetics of human alcohol-related hepatocellular carcinoma.
Author: Nahon, Pierre|Nault, Jean-Charles
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Journal: Medicine (Baltimore). 2017 Mar;96(12):e6127.
Title: Influence of polymorphisms in the Wnt/beta-catenin pathway genes on hepatocellular carcinoma risk in a Chinese Han population.
Author: Li, Qing-Min|Zhang, Feng-Qin|Li, Ya-Feng|Xian, Qing-Jie|Zhang, Yan-Qiang|Li, Peng
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Journal: Int J Cancer. 2017 Jul 15;141(2):354-363.
Title: Hepatic expression of oncogenes Bmi1 and Dkk1 is up-regulated in hepatitis B virus surface antigen-transgenic mice and can be induced by treatment with HBV particles or lipopolysaccharides in vitro.
Author: Zhang, Rui|Real, Catherine I|Liu, Chao|Baba, Hideo A|Gerken, Guido|Lu, Mengji|Broering, Ruth
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Journal: Infect Agent Cancer. 2017 May 19;12:27.
Title: Frequency and geographic distribution of TERT promoter mutations in primary hepatocellular carcinoma.
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Journal: J Hepatol. 2017 Oct;67(4):727-738.
Title: Histological subtypes of hepatocellular carcinoma are related to gene mutations and molecular tumour classification.
Author: Calderaro, Julien|Couchy, Gabrielle|Imbeaud, Sandrine|Amaddeo, Giuliana|Letouze, Eric|Blanc, Jean-Frederic|Laurent, Christophe|Hajji, Yacine|Azoulay, Daniel|Bioulac-Sage, Paulette|Nault, Jean-Charles|Zucman-Rossi, Jessica
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Journal: PLoS One. 2017 Jun 26;12(6):e0179543.
Title: Meta-analysis of miRNA expression profiles for prostate cancer recurrence following radical prostatectomy.
Author: Pashaei, Elnaz|Pashaei, Elham|Ahmady, Maryam|Ozen, Mustafa|Aydin, Nizamettin
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Journal: J Hepatol. 2017 Nov;67(5):1074-1083.
Title: Molecular classification of hepatocellular adenoma in clinical practice.
Author: Nault, Jean-Charles|Paradis, Valerie|Cherqui, Daniel|Vilgrain, Valerie|Zucman-Rossi, Jessica
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Journal: Mol Cancer Ther. 2017 Nov;16(11):2609-2617.
Title: TTK Inhibitors as a Targeted Therapy for CTNNB1 (beta-catenin) Mutant Cancers.
Author: Zaman, Guido J R|de Roos, Jeroen A D M|Libouban, Marion A A|Prinsen, Martine B W|de Man, Jos|Buijsman, Rogier C|Uitdehaag, Joost C M
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Journal: Am J Pathol. 2017 Nov;187(11):2473-2485.
Title: Thyroid Hormone Receptor-beta Agonist GC-1 Inhibits Met-beta-Catenin-Driven Hepatocellular Cancer.
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Journal: J Hepatol. 2017 Dec;67(6):1222-1231.
Title: Trunk mutational events present minimal intra- and inter-tumoral heterogeneity in hepatocellular carcinoma.
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Journal: Mol Cancer. 2017 Aug 30;16(1):149.
Title: The biology of Hepatocellular carcinoma: implications for genomic and immune therapies.
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Journal: EMBO Mol Med. 2017 Nov;9(11):1589-1604.
Title: Mutant CTNNB1 and histological heterogeneity define metabolic subtypes of hepatoblastoma.
Author: Crippa, Stefania|Ancey, Pierre-Benoit|Vazquez, Jessica|Angelino, Paolo|Rougemont, Anne-Laure|Guettier, Catherine|Zoete, Vincent|Delorenzi, Mauro|Michielin, Olivier|Meylan, Etienne
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Journal: Oncotarget. 2017 Sep 28;8(70):114526-114539.
Title: Oncogenic dependency on beta-catenin in liver cancer cell lines correlates with pathway activation.
Author: Ding, Zhihu|Shi, Chaomei|Jiang, Lan|Tolstykh, Tatiana|Cao, Hui|Bangari, Dinesh S|Ryan, Susan|Levit, Mikhail|Jin, Taiguang|Mamaat, Karl|Yu, Qunyan|Qu, Hui|Hopke, Joern|Cindhuchao, May|Hoffmann, Dietmar|Sun, Fangxian|Helms, Mike W|Jahn-Hofmann, Kerstin|Sche
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Journal: Indian J Cancer. 2017 Oct-Dec;54(4):634-639.
Title: Clinicopathologic characteristics of Wnt/beta-catenin-deregulated hepatocellular carcinoma.
Author: Verma, Anuj|Bal, Munita|Ramadwar, Mukta|Deodhar, Kedar|Patil, Prachi|Goel, Mahesh
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Journal: J Cell Physiol. 2018 Jan;233(1):79-87.
Title: New advances of TMEM88 in cancer initiation and progression, with special emphasis on Wnt signaling pathway.
Author: Ge, Yun-Xuan|Wang, Chang-Hui|Hu, Fu-Yong|Pan, Lin-Xin|Min, Jie|Niu, Kai-Yuan|Zhang, Lei|Li, Jun|Xu, Tao
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Journal: Hepatology. 2018 May;67(5):1807-1822.
Title: beta-catenin deficiency in hepatocytes aggravates hepatocarcinogenesis driven by oncogenic beta-catenin and MET.
Author: Liang, Yan|Feng, Yun|Zong, Min|Wei, Xu-Fu|Lee, Jin|Feng, Yukuan|Li, Hairi|Yang, Guang-Shun|Wu, Zhong-Jun|Fu, Xiang-Dong|Feng, Gen-Sheng
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Journal: J Exp Clin Cancer Res. 2018 Jan 27;37(1):13.
Title: Over-expression of oncigenic pesudogene DUXAP10 promotes cell proliferation and invasion by regulating LATS1 and beta-catenin in gastric cancer.
Author: Xu, Yongcan|Yu, Xiang|Wei, Chenchen|Nie, Fengqi|Huang, Mingde|Sun, Ming
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Journal: Oncol Lett. 2018 Jan;15(1):528-532.
Title: Targeted sequencing of cancer-associated genes in hepatocellular carcinoma using next-generation sequencing.
Author: Morishita, Asahiro|Iwama, Hisakazu|Fujihara, Shintaro|Watanabe, Miwako|Fujita, Koji|Tadokoro, Tomoko|Ohura, Kyoko|Chiyo, Taiga|Sakamoto, Teppei|Mimura, Shima|Nomura, Takako|Tani, Joji|Yoneyama, Hirohito|Okano, Keiichi|Suzuki, Yasuyuki|Himoto, Takashi|Masa
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Journal: Biochim Biophys Acta Mol Basis Dis. 2018 Jun;1864(6 Pt B):2360-2368.
Title: Whole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversity.
Author: Liu, Zhen-Hao|Lian, Bao-Feng|Dong, Qiong-Zhu|Sun, Han|Wei, Jin-Wang|Sheng, Yuan-Yuan|Li, Wei|Li, Yi-Xue|Xie, Lu|Liu, Lei|Qin, Lun-Xiu
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Journal: Gene Expr. 2018 May 18;18(2):135-147.
Title: The Effect of Selective c-MET Inhibitor on Hepatocellular Carcinoma in the MET-Active, beta-Catenin-Mutated Mouse Model.
Author: Zhan, Na|Michael, Adeola Adebayo|Wu, Kaiyuan|Zeng, Gang|Bell, Aaron|Tao, Junyan|Monga, Satdarshan P
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Journal: Int J Mol Med. 2018 May;41(5):2813-2831.
Title: Downregulated miR-23b-3p expression acts as a predictor of hepatocellular carcinoma progression: A study based on public data and RT-qPCR verification.
Author: He, Rong-Quan|Wu, Pei-Rong|Xiang, Xue-Lian|Yang, Xia|Liang, Hai-Wei|Qiu, Xiao-Hui|Yang, Li-Hua|Peng, Zhi-Gang|Chen, Gang
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Journal: Oncologist. 2018 May;23(5):586-593.
Title: Next-Generation Sequencing of Circulating Tumor DNA Reveals Frequent Alterations in Advanced Hepatocellular Carcinoma.
Author: Ikeda, Sadakatsu|Tsigelny, Igor F|Skjevik, Age A|Kono, Yuko|Mendler, Michel|Kuo, Alexander|Sicklick, Jason K|Heestand, Gregory|Banks, Kimberly C|Talasaz, AmirAli|Lanman, Richard B|Lippman, Scott|Kurzrock, Razelle
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Journal: Histopathology. 2018 Jul;73(1):101-108.
Title: Hepatic angiomyolipoma: mutation analysis and immunohistochemical pitfalls in diagnosis.
Author: Yan, Zhen|Grenert, James P|Joseph, Nancy M|Ren, Chuanli|Chen, Xin|Shafizadeh, Nafis|Kakar, Sanjay
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Journal: Gene Expr. 2018 Aug 22;18(3):209-219.
Title: Hepatocyte Wnts Are Dispensable During Diethylnitrosamine and Carbon Tetrachloride-Induced Injury and Hepatocellular Cancer.
Author: Preziosi, Morgan|Poddar, Minakshi|Singh, Sucha|Monga, Satdarshan P
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Journal: J Hepatol. 2018 Jun;68(6):1203-1213.
Title: AXIN deficiency in human and mouse hepatocytes induces hepatocellular carcinoma in the absence of beta-catenin activation.
Author: Abitbol, Shirley|Dahmani, Rajae|Coulouarn, Cedric|Ragazzon, Bruno|Mlecnik, Bernhard|Senni, Nadia|Savall, Mathilde|Bossard, Pascale|Sohier, Pierre|Drouet, Valerie|Tournier, Emilie|Dumont, Florent|Sanson, Romain|Calderaro, Julien|Zucman-Rossi, Jessica|Vasse
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Journal: Gut. 2018 Apr 12. pii: gutjnl-2017-315448.
Title: beta-catenin-activated hepatocellular carcinomas are addicted to fatty acids.
Author: Senni, Nadia|Savall, Mathilde|Cabrerizo Granados, David|Alves-Guerra, Marie-Clotilde|Sartor, Chiara|Lagoutte, Isabelle|Gougelet, Angelique|Terris, Benoit|Gilgenkrantz, Helene|Perret, Christine|Colnot, Sabine|Bossard, Pascale
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Journal: Biomedicines. 2018 Apr 17;6(2). pii: biomedicines6020046.
Title: Tumor Molecular Profiling for an Individualized Approach to the Treatment of Hepatocellular Carcinoma: A Patient Case Study.
Author: Posadas, Kristine|Ankola, Anita|Yang, Zhaohai|Yee, Nelson S
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Journal: Ann Hepatol. 2018 May-June;17(3):444-460.
Title: Antiproliferative Effects of Epigenetic Modifier Drugs Through E-cadherin Up-regulation in Liver Cancer Cell Lines.
Author: Uribe, Diego|Cardona, Andres|Esposti, Davide Degli|Cros, Marie-Pierre|Cuenin, Cyrille|Herceg, Zdenko|Camargo, Mauricio|Cortes-Mancera, Fabian M
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Journal: Int J Mol Med. 2018 Aug;42(2):713-725.
Title: Multilayered prevention and treatment of chronic inflammation, organ fibrosis and cancer associated with canonical WNT/betacatenin signaling activation (Review).
Author: Katoh, Masaru
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Journal: Hum Pathol. 2018 Jun 24. pii: S0046-8177(18)30240-5.
Title: Genomic structures of dysplastic nodule and concurrent hepatocellular carcinoma.
Author: Lee, Minho|Kim, Kyung|Kim, Shinn Young|Jung, Seung-Hyun|Yoon, Jonghwan|Kim, Min Sung|Park, Hyeon-Chun|Jung, Eun Sun|Chung, Yeun-Jun|Lee, Sug Hyung
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Journal: Clin Cancer Res. 2018 Jun 27. pii: 1078-0432.CCR-17-3588.
Title: Phase II Studies with Refametinib or Refametinib plus Sorafenib in Patients with RAS-Mutated Hepatocellular Carcinoma.
Author: Lim, Ho Yeong|Merle, Philippe|Weiss, Karl Heinz|Yau, Thomas|Ross, Paul|Mazzaferro, Vincenzo|Blanc, Jean-Frederic|Ma, Yuk Ting|Yen, Chia Jui|Kocsis, Judit|Choo, Su Pin|Sukeepaisarnjaroen, Wattana|Gerolami, Rene|Dufour, Jean-Francois|Gane, Edward J|Ryoo, Ba
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Journal: Biomed Pharmacother. 2018 Oct;106:483-490.
Title: MicroRNA-298 represses hepatocellular carcinoma progression by inhibiting CTNND1-mediated Wnt/beta-catenin signaling.
Author: Cao, Ningjia|Mu, Liang|Yang, Wei|Liu, Li|Liang, Liang|Zhang, Hong
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Journal: Front Genet. 2018 Jul 19;9:261.
Title: Host and Viral Genetic Variation in HBV-Related Hepatocellular Carcinoma.
Author: An, Ping|Xu, Jinghang|Yu, Yanyan|Winkler, Cheryl A
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Journal: Am J Pathol. 2018 Sep 8. pii: S0002-9440(17)31145-8.
Title: High Frequency of beta-Catenin Mutations in Mouse Hepatocellular Carcinomas Induced by a Nongenotoxic Constitutive Androstane Receptor Agonist.
Author: Mattu, Sandra|Saliba, Christian|Sulas, Pia|Zavattari, Patrizia|Perra, Andrea|Kowalik, Marta A|Monga, Satdarshan P|Columbano, Amedeo
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Journal: Clin Cancer Res. 2018 Sep 21. pii: 1078-0432.CCR-18-0088.
Title: Multi-modal meta-analysis of 1494 hepatocellular carcinoma samples reveals significant impact of consensus driver genes on phenotypes.
Author: Chaudhary, Kumardeep|Poirion, Olivier B|Lu, Liangqun|Huang, Sijia|Ching, Travers|Garmire, Lana X
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Journal: Mol Cancer Res. 2018 Sep 26. pii: 1541-7786.MCR-18-0054.
Title: Oncogenic STRAP Supports Hepatocellular Carcinoma Growth by Enhancing Wnt/beta-Catenin Signaling.
Author: Wang, Wenhui|Li, Shan|Liu, Pengyu|Sideras, Kostandinos|van de Werken, Harmen J G|van der Heide, Marieke|Cao, Wanlu|Lavrijsen, Marla|Peppelenbosch, Maikel P|Bruno, Marco|Pan, Qiuwei|Smits, Ron
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Journal: Cancers (Basel). 2018 Sep 29;10(10). pii: cancers10100367.
Title: Molecular Scoring of Hepatocellular Carcinoma for Predicting Metastatic Recurrence and Requirements of Systemic Chemotherapy.
Author: Nishida, Naoshi|Nishimura, Takafumi|Kaido, Toshimi|Minaga, Kosuke|Yamao, Kentaro|Kamata, Ken|Takenaka, Mamoru|Ida, Hiroshi|Hagiwara, Satoru|Minami, Yasunori|Sakurai, Toshiharu|Watanabe, Tomohiro|Kudo, Masatoshi
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