Primary Site >> Biliary tract Cancer

Gene >> CTNNB1

Journal: Hepatology. 1998 Apr;27(4):974-82.
Title: Expression of E-cadherin, alpha-catenin, beta-catenin, and CD44 (standard and variant isoforms) in human cholangiocarcinoma: an immunohistochemical study.
Author: Ashida, K|Terada, T|Kitamura, Y|Kaibara, N
PMID: 9537436
Journal: Cancer Res. 2001 Apr 15;61(8):3406-9.
Title: Beta-catenin mutations in biliary tract cancers: a population-based study in China.
Author: Rashid, A|Gao, Y T|Bhakta, S|Shen, M C|Wang, B S|Deng, J|Fraumeni, J F Jr|Hsing, A W
PMID: 11309300
Journal: Int J Oncol. 2001 Dec;19(6):1099-107.
Title: Exogenous expression of E-cadherin in gallbladder carcinoma cell line G-415 restores its cellular polarity and differentiation.
Author: Jiao, W|Miyazaki, K|Kitajima, Y
PMID: 11713577
Journal: Mod Pathol. 2001 Sep;14(9):900-5.
Title: Altered expression of beta-catenin without genetic mutation in intrahepatic cholangiocarcinoma.
Author: Sugimachi, K|Taguchi, K|Aishima, S|Tanaka, S|Shimada, M|Kajiyama, K|Sugimachi, K|Tsuneyoshi, M
PMID: 11557787
Journal: Liver. 2002 Feb;22(1):43-50.
Title: The mode of tumour progression in combined hepatocellular carcinoma and cholangiocarcinoma: an immunohistochemical analysis of E-cadherin, alpha-catenin and beta-catenin.
Author: Asayama, Yoshiki|Taguchi Ki, Ken-ichi|Aishima Si, Shin-ichi|Nishi, Hidehiro|Masuda, Kouji|Tsuneyoshi, Masazumi
PMID: 11906618
Journal: Am J Surg Pathol. 2002 Jun;26(6):758-66.
Title: Mutation and altered expression of beta-catenin during gallbladder carcinogenesis.
Author: Chang, Hee Jin|Jee, Chang Do|Kim, Woo Ho
PMID: 12023580
Journal: Surg Oncol Clin N Am. 2002 Oct;11(4):995-1009.
Title: Cellular and molecular biology of biliary tract cancers.
Author: Rashid, Asif
PMID: 12607585
Journal: Int J Mol Med. 2003 Jan;11(1):65-9.
Title: Mutation analysis of K-ras and beta-catenin genes related to O6-methylguanin-DNA methyltransferase and mismatch repair protein status in human gallbladder carcinoma.
Author: Kohya, Naohiko|Kitajima, Yoshihiko|Kitahara, Kenji|Miyazaki, Kohji
PMID: 12469220
Journal: J Exp Clin Cancer Res. 2003 Jun;22(2):321-8.
Title: Frequent beta-catenin alteration in gallbladder carcinomas.
Author: Kimura, Y|Furuhata, T|Mukaiya, M|Kihara, C|Kawakami, M|Okita, K|Yanai, Y|Zenbutsu, H|Satoh, M|Ichimiya, S|Hirata, K
PMID: 12866584
Journal: Eur J Gastroenterol Hepatol. 2003 Aug;15(8):907-13.
Title: Alteration of the fragile histidine triad gene in intrahepatic cholangiocarcinoma.
Author: Koch, Eileen|Fiedler, Wolfgang|Tannapfel, Andrea|Ballhausen, Wolfgang G
PMID: 12867802
Journal: Hum Pathol. 2003 Sep;34(9):902-10.
Title: Molecular and immunohistochemical analysis of intraductal papillary neoplasms of the biliary tract.
Author: Abraham, Susan C|Lee, Jae-Hyuk|Hruban, Ralph H|Argani, Pedram|Furth, Emma E|Wu, Tsung-Teh
PMID: 14562286
Journal: J Hepatobiliary Pancreat Surg. 2004;11(6):409-16.
Title: Immunohistochemical study of characteristics of bile duct dysplasia evaluated on the basis of expression of metastasis/invasion-related factors and p53.
Author: Chiba, Hideo|Nagai, Hideo|Ohdaira, Takeshi|Yasuda, Yoshikazu|Saito, Ken
PMID: 15619017
Journal: Hepatology. 2005 Jan;41(1):5-15.
Title: Cholangiocarcinoma: molecular targeting strategies for chemoprevention and therapy.
Author: Sirica, Alphonse E
PMID: 15690474
Journal: Cancer Res Treat. 2005 Jun;37(3):171-6.
Title: Co-expression of cox-2, C-met and beta-catenin in cells forming invasive front of gallbladder cancer.
Author: Moon, Woo Sung|Park, Ho Sung|Lee, Ho|Pai, Rama|Tarnawski, Andrzej S|Kim, Kyung Ryoul|Jang, Kyu Yun
PMID: 19956499
Journal: J Clin Pathol. 2005 Dec;58(12):1249-54.
Title: FAT, E-cadherin, beta catenin, HER 2/neu, Ki67 immuno-expression, and histological grade in intrahepatic cholangiocarcinoma.
Author: Settakorn, J|Kaewpila, N|Burns, G F|Leong, A S-Y
PMID: 16311342
Journal: Anticancer Res. 2005 Nov-Dec;25(6B):4249-54.
Title: E-cadherin and beta-catenin expression in normal, inflamed and cancerous gallbladder tissue.
Author: Puhalla, Harald|Herberger, Beate|Soleiman, Afschin|Filipits, Martin|Laengle, Fritz|Gruenberger, Thomas|Wrba, Fritz
PMID: 16309224
Journal: Int J Oncol. 2005 Oct;27(4):973-80.
Title: Immunohistochemical and mutational analyses of Wnt signaling components and target genes in intrahepatic cholangiocarcinomas.
Author: Tokumoto, Noriaki|Ikeda, Satoshi|Ishizaki, Yasuyo|Kurihara, Takeshi|Ozaki, Shinji|Iseki, Masahiko|Shimizu, Yosuke|Itamoto, Toshiyuki|Arihiro, Koji|Okajima, Masazumi|Asahara, Toshimasa
PMID: 16142313
Journal: Ann Surg Oncol. 2005 May;12(5):354-63. Epub 2005 Mar 31.
Title: Tumor progression through epigenetic gene silencing of O(6)-methylguanine-DNA methyltransferase in human biliary tract cancers.
Author: Koga, Yasuo|Kitajima, Yoshihiko|Miyoshi, Atsushi|Sato, Ken|Kitahara, Kenji|Soejima, Hidenobu|Miyazaki, Kohji
PMID: 15915369
Journal: Hepatogastroenterology. 2006 Jan-Feb;53(67):28-32.
Title: Expression of E-cadherin and beta-catenin in the adenoma-carcinoma sequence of ampulla of Vater cancer.
Author: Park, Sunhoo|Kim, Sun Whe|Lee, Byung Lan|Jung, Eun Ji|Kim, Woo Ho
PMID: 16506371
Journal: Virchows Arch. 2006 Nov;449(5):585-90.
Title: Intrahepatic sarcomatoid cholangiocarcinoma of round cell variant: a case report and immunohistochemical studies.
Author: Sato, Katsuaki|Murai, Hiroshi|Ueda, Yoshimichi|Katsuda, Shogo
PMID: 17033799
Journal: Oncology. 2006;71(1-2):102-10.
Title: Frequent occurrence of abnormal E-cadherin/beta-catenin protein expression in advanced gallbladder cancers and its association with decreased apoptosis.
Author: Hirata, Kenro|Ajiki, Tetsuo|Okazaki, Taro|Horiuchi, Hideki|Fujita, Tsunenori|Kuroda, Yoshikazu
PMID: 17341890
Journal: Ann Surg Oncol. 2007 Mar;14(3):1200-11. Epub 2006 Dec 23.
Title: Bile duct cyst as precursor to biliary tract cancer.
Author: Soreide, Kjetil|Soreide, Jon Arne
PMID: 17187167
Journal: Liver Int. 2007 Nov;27(9):1174-84.
Title: Immunohistochemical analysis of the progression of flat and papillary preneoplastic lesions in intrahepatic cholangiocarcinogenesis in hepatolithiasis.
Author: Itatsu, Keita|Zen, Yoh|Ohira, Shusaku|Ishikawa, Akira|Sato, Yasunori|Harada, Kenichi|Ikeda, Hiroko|Sasaki, Motoko|Nimura, Yuji|Nakanuma, Yasuni
PMID: 17919228
Journal: Cancer Res. 2008 Jan 15;68(2):553-60.
Title: Cyclooxygenase-2-derived prostaglandin E2 activates beta-catenin in human cholangiocarcinoma cells: evidence for inhibition of these signaling pathways by omega 3 polyunsaturated fatty acids.
Author: Lim, Kyu|Han, Chang|Xu, Lihong|Isse, Kumiko|Demetris, Anthony J|Wu, Tong
PMID: 18199552
Journal: Vopr Onkol. 2008;54(4):417-33.
Title: [The significance of immunohistochemistry in the investigation of liver neoplasms: differential diagnosis, prognostic markers].
Author: Pozharisskii, K M|Granov, D A|Ten, V P|Kubaibergenova, A G|Leenman, E E|Rasskazov, A I
PMID: 18942395
Journal: Ann Diagn Pathol. 2008 Dec;12(6):430-2.
Title: Morule-like features and tumor-associated lymphoid proliferation in gallbladder carcinoma.
Author: Sakai, Yu|Sano, Shinji|Koike, Hiroshi
PMID: 18995208
Journal: Oncology. 2009;76(4):293-300.
Title: A comprehensive analysis of immunohistochemical studies in intrahepatic cholangiocarcinoma using the survival tree model.
Author: Iguchi, Tomohiro|Yamashita, Natsumi|Aishima, Shinichi|Kuroda, Yousuke|Terashi, Takahiro|Sugimachi, Keishi|Taguchi, Ken-ichi|Taketomi, Akinobu|Maehara, Yoshihiko|Tsuneyoshi, Masazumi
PMID: 19262069
Journal: World J Hepatol. 2009 Oct 31;1(1):35-42.
Title: Multistep carcinogenesis of perihilar cholangiocarcinoma arising in the intrahepatic large bile ducts.
Author: Nakanuma, Yasuni|Sasaki, Motoko|Sato, Yasunori|Ren, Xiangshan|Ikeda, Hiroko|Harada, Kenichi
PMID: 21160963
Journal: J Hepatobiliary Pancreat Sci. 2010 May;17(3):211-22.
Title: Tumorigenesis and phenotypic characteristics of mucin-producing bile duct tumors: an immunohistochemical approach.
Author: Nakanuma, Yasuni|Zen, Yoh|Harada, Kenichi|Ikeda, Hiroko|Sato, Yasunori|Uehara, Takeshi|Sasaki, Motoko
PMID: 19680592
Journal: Int J Oncol. 2010 Jan;36(1):49-58.
Title: Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition.
Author: Kiesslich, Tobias|Alinger, Beate|Wolkersdorfer, Gernot W|Ocker, Matthias|Neureiter, Daniel|Berr, Frieder
PMID: 19956832
Journal: J Surg Oncol. 2010 Apr 1;101(5):356-62.
Title: Loss of E-cadherin and beta-catenin is correlated with poor prognosis of ampullary neoplasms.
Author: Hsu, Hui-Ping|Shan, Yan-Shen|Jin, Ying-Tai|Lai, Ming-Derg|Lin, Pin-Wen
PMID: 20119975
Journal: Semin Liver Dis. 2011 May;31(2):173-87.
Title: Genetics of hepatobiliary carcinogenesis.
Author: Nault, Jean-Charles|Zucman-Rossi, Jessica
PMID: 21538283
Journal: Hepatobiliary Pancreat Dis Int. 2011 Apr;10(2):179-84.
Title: Xanthogranulomatous cholecystitis: a premalignant condition?
Author: Ghosh, Mila|Sakhuja, Puja|Agarwal, Anil K
PMID: 21459725
Journal: Oncologist. 2012;17(1):72-9.
Title: Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping.
Author: Borger, Darrell R|Tanabe, Kenneth K|Fan, Kenneth C|Lopez, Hector U|Fantin, Valeria R|Straley, Kimberly S|Schenkein, David P|Hezel, Aram F|Ancukiewicz, Marek|Liebman, Hannah M|Kwak, Eunice L|Clark, Jeffrey W|Ryan, David P|Deshpande, Vikram|Dias-Santagata,
PMID: 22180306
Journal: Hepatogastroenterology. 2012 Jun;59(116):1241-4.
Title: Clinicopathological significance of E-cadherin, beta-catenin and epidermal growth factor receptor expression in intrahepatic cholangiocarcinoma.
Author: Gu, Mi Jin|Choi, Joon Hyuk
PMID: 22281980
Journal: Cancer Sci. 2012 Jun;103(6):1165-71.
Title: Significance of epithelial growth factor in the epithelial-mesenchymal transition of human gallbladder cancer cells.
Author: Sasaki, Takamitsu|Kuniyasu, Hiroki|Luo, Yi|Kato, Daisuke|Shinya, Satoshi|Fujii, Kiyomu|Ohmori, Hitoshi|Yamashita, Yuichi
PMID: 22404757
Journal: Gastroenterology. 2012 Jul;143(1):246-56.e8.
Title: MicroRNA-26a promotes cholangiocarcinoma growth by activating beta-catenin.
Author: Zhang, Jinqiang|Han, Chang|Wu, Tong
PMID: 22484120
Journal: Int J Oncol. 2012 Aug;41(2):573-82.
Title: Angiotensin II enhances epithelial-to-mesenchymal transition through the interaction between activated hepatic stellate cells and the stromal cell-derived factor-1/CXCR4 axis in intrahepatic cholangiocarcinoma.
Author: Okamoto, Koichi|Tajima, Hidehiro|Nakanuma, Shinichi|Sakai, Seisho|Makino, Isamu|Kinoshita, Jun|Hayashi, Hironori|Nakamura, Keishi|Oyama, Katsunobu|Nakagawara, Hisatoshi|Fujita, Hideto|Takamura, Hiroyuki|Ninomiya, Itasu|Kitagawa, Hirohisa|Fushida, Sachio|F
PMID: 22664794
Journal: World J Gastroenterol. 2012 Jul 28;18(28):3673-80.
Title: Intraductal neoplasm of the intrahepatic bile duct: clinicopathological study of 24 cases.
Author: Naito, Yoshiki|Kusano, Hironori|Nakashima, Osamu|Sadashima, Eiji|Hattori, Satoshi|Taira, Tomoki|Kawahara, Akihiko|Okabe, Yoshinobu|Shimamatsu, Kazuhide|Taguchi, Jun|Momosaki, Seiya|Irie, Koji|Yamaguchi, Rin|Yokomizo, Hiroshi|Nagamine, Michiko|Fukuda, Seij
PMID: 22851859
Journal: Transl Cancer Res. 2013 Feb 1;2(1):6-17.
Title: Utilizing signature-score to identify oncogenic pathways of cholangiocarcinoma.
Author: Hsiao, Tzu-Hung|Chen, Hung-I Harry|Lu, Jo-Yang|Lin, Pei-Ying|Keller, Charles|Comerford, Sarah|Tomlinson, Gail E|Chen, Yidong
PMID: 23905013
Journal: Cancer Sci. 2013 Oct;104(10):1303-8.
Title: Inhibition of Wnt/beta-catenin signaling downregulates P-glycoprotein and reverses multi-drug resistance of cholangiocarcinoma.
Author: Shen, Dong-Yan|Zhang, Wei|Zeng, Xin|Liu, Chang-Qin
PMID: 23822562
Journal: Oncol Rep. 2013 Sep;30(3):1430-8.
Title: Inhibition of Wnt signaling induces cell apoptosis and suppresses cell proliferation in cholangiocarcinoma cells.
Author: Zhang, Kun-Song|Zhou, Qi|Wang, Ya-Feng|Liang, Li-Jian
PMID: 23799613
Journal: J Hepatol. 2013 Sep;59(3):518-27.
Title: MiR-20a triggers metastasis of gallbladder carcinoma.
Author: Chang, Yanxin|Liu, Chen|Yang, Jiahe|Liu, Gaomiyang|Feng, Feiling|Tang, Jing|Hu, Liang|Li, Liang|Jiang, Feng|Chen, Caiyang|Wang, Ruoyu|Yang, Yingcheng|Jiang, Xiaoqing|Wu, Mengchao|Chen, Lei|Wang, Hongyang
PMID: 23665284
Journal: Mol Cell Biol. 2013 Sep;33(17):3416-25.
Title: Oncogenic activity of retinoic acid receptor gamma is exhibited through activation of the Akt/NF-kappaB and Wnt/beta-catenin pathways in cholangiocarcinoma.
Author: Huang, Gui-Li|Luo, Qi|Rui, Gang|Zhang, Wei|Zhang, Qiu-Yan|Chen, Qing-Xi|Shen, Dong-Yan
PMID: 23798555
Journal: Saudi J Gastroenterol. 2013 Jan-Feb;19(1):34-9.
Title: p53 and beta-catenin expression in gallbladder tissues and correlation with tumor progression in gallbladder cancer.
Author: Ghosh, Mila|Sakhuja, Puja|Singh, Shivendra|Agarwal, Anil K
PMID: 23319036
Journal: PLoS One. 2013 Apr 30;8(4):e62844.
Title: Suppression of cholangiocarcinoma cell growth by human umbilical cord mesenchymal stem cells: a possible role of Wnt and Akt signaling.
Author: Liu, Juan|Han, Guoqing|Liu, Hui|Qin, Chengyong
PMID: 23646150
Journal: Mod Pathol. 2014 Jan;27(1):73-86.
Title: Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways.
Author: Schlitter, Anna Melissa|Born, Diana|Bettstetter, Marcus|Specht, Katja|Kim-Fuchs, Corina|Riener, Marc-Oliver|Jeliazkova, Petia|Sipos, Bence|Siveke, Jens T|Terris, Benoit|Zen, Yoh|Schuster, Tibor|Hofler, Heinz|Perren, Aurel|Kloppel, Gunter|Esposito, Irene
PMID: 23828315
Journal: Oncol Lett. 2014 Oct;8(4):1687-1692. Epub 2014 Jul 11.
Title: Signet ring cell carcinoma of the ampulla of Vater: Immunophenotype and differentiation.
Author: Wen, Xue|Wu, Weiqiang|Wang, Bo|Yao, Hongtian|Teng, Xiaodong
PMID: 25202392
Journal: Ann Surg Oncol. 2014 Nov;21(12):3827-34.
Title: Genomic profiling of intrahepatic cholangiocarcinoma: refining prognosis and identifying therapeutic targets.
Author: Zhu, Andrew X|Borger, Darrell R|Kim, Yuhree|Cosgrove, David|Ejaz, Aslam|Alexandrescu, Sorin|Groeschl, Ryan Thomas|Deshpande, Vikram|Lindberg, James M|Ferrone, Cristina|Sempoux, Christine|Yau, Thomas|Poon, Ronnie|Popescu, Irinel|Bauer, Todd W|Gamblin, T Cl
PMID: 24889489
Journal: Int J Oncol. 2014 Aug;45(2):691-8.
Title: The role of nuclear EpICD in extrahepatic cholangiocarcinoma: association with beta-catenin.
Author: Jachin, Sarangerel|Bae, Jun Sang|Sung, Jong Jin|Park, Ho Sung|Jang, Kyu Yun|Chung, Myoung Ja|Kim, Dae Gohn|Moon, Woo Sung
PMID: 24888903
Journal: Tumour Biol. 2014 Sep;35(9):8645-52.
Title: Loss of E-cadherin promotes migration and invasion of cholangiocarcinoma cells and serves as a potential marker of metastasis.
Author: Techasen, Anchalee|Loilome, Watcharin|Namwat, Nisana|Khuntikeo, Narong|Puapairoj, Anucha|Jearanaikoon, Patcharee|Saya, Hideyuki|Yongvanit, Puangrat
PMID: 24867095
Journal: PLoS One. 2014 May 9;9(5):e96860.
Title: Comprehensive multiple molecular profile of epithelial mesenchymal transition in intrahepatic cholangiocarcinoma patients.
Author: Huang, Xiao-Yong|Zhang, Chi|Cai, Jia-Bin|Shi, Guo-Ming|Ke, Ai-Wu|Dong, Zhao-Ru|Zhang, Peng-Fei|Fan, Jia|Peng, Bao-Gang|Zhou, Jian
PMID: 24816558
Journal: Indian J Pathol Microbiol. 2014 Jan-Mar;57(1):9-12.
Title: Mutation profiling in gallbladder cancer in Indian population.
Author: Kumari, Niraj|Corless, Christopher L|Warrick, Andrea|Beadling, Carol|Nelson, Dylan|Neff, Tanay|Krishnani, Narendra|Kapoor, Vinay Kumar
PMID: 24739824
Journal: J Hepatol. 2014 Aug;61(2):325-32.
Title: EGF/EGFR axis contributes to the progression of cholangiocarcinoma through the induction of an epithelial-mesenchymal transition.
Author: Claperon, Audrey|Mergey, Martine|Nguyen Ho-Bouldoires, Thanh Huong|Vignjevic, Danijela|Wendum, Dominique|Chretien, Yves|Merabtene, Fatiha|Frazao, Alexandra|Paradis, Valerie|Housset, Chantal|Guedj, Nathalie|Fouassier, Laura
PMID: 24704591
Journal: PLoS One. 2014 Mar 3;9(3):e90308.
Title: The Wnt antagonist sFRP1 as a favorable prognosticator in human biliary tract carcinoma.
Author: Kang, Pengcheng|Wan, Ming|Huang, Peng|Li, Chunlong|Wang, Zhidong|Zhong, Xiangyu|Hu, Zhanliang|Tai, Sheng|Cui, Yunfu
PMID: 24594839
Journal: Tumour Biol. 2014 Jun;35(6):5357-67.
Title: Activated macrophages promote Wnt/beta-catenin signaling in cholangiocarcinoma cells.
Author: Loilome, Watcharin|Bungkanjana, Pornpan|Techasen, Anchalee|Namwat, Nisana|Yongvanit, Puangrat|Puapairoj, Anucha|Khuntikeo, Narong|Riggins, Gregory J
PMID: 24549785
Journal: Gut Liver. 2014 Jan;8(1):94-101.
Title: Differential expression of E-cadherin, beta-catenin, and S100A4 in intestinal type and nonintestinal type ampulla of Vater cancers.
Author: Sung, Rohyun|Kang, Li|Han, Joung-Ho|Choi, Jae-Woon|Lee, Sang Hwa|Lee, Tae Hoon|Park, Sang-Heum|Kim, Hong Ja|Lee, Eaum Seok|Kim, Young Suk|Choi, Young Woo|Park, Seon Mee
PMID: 24516707
Journal: Oncogene. 2014 Oct 16;33(42):4997-5005.
Title: GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN.
Author: Chen, W-T|Zhu, G|Pfaffenbach, K|Kanel, G|Stiles, B|Lee, A S
PMID: 24141775
Journal: J Surg Oncol. 2014 Feb;109(2):98-103.
Title: Molecular factors associated with recurrence and survival following hepatectomy in patients with intrahepatic cholangiocarcinoma: a guide to adjuvant clinical trials.
Author: Schiffman, Suzanne C|Nowacki, Michael R|Spencer, Lena|McMasters, Kelly M|Scoggins, Charles R|Martin, Robert C G
PMID: 24122302
Journal: J Clin Pathol. 2014 Mar;67(3):229-34.
Title: Epithelial-mesenchymal transition phenotypes are associated with patient survival in intrahepatic cholangiocarcinoma.
Author: Gu, Mi Jin|Choi, Joon Hyuk
PMID: 24062361
Journal: BMC Cancer. 2015 Nov 16;15:903.
Title: Dual role of CD44 isoforms in ampullary adenocarcinoma: CD44s predicts poor prognosis in early cancer and CD44nu is an indicator for recurrence in advanced cancer.
Author: Wu, Cheng-Lin|Chao, Ying-Jui|Yang, Ta-Ming|Chen, Yi-Ling|Chang, Kung-Chao|Hsu, Hui-Ping|Shan, Yan-Shen|Lai, Ming-Derg
PMID: 26572077
Journal: PLoS One. 2015 Oct 26;10(10):e0141168.
Title: miR-221 Promotes Epithelial-Mesenchymal Transition through Targeting PTEN and Forms a Positive Feedback Loop with beta-catenin/c-Jun Signaling Pathway in Extra-Hepatic Cholangiocarcinoma.
Author: Li, Jianguo|Yao, Lei|Li, Guodong|Ma, Donglai|Sun, Chen|Gao, Shuang|Zhang, Ping|Gao, Feng
PMID: 26501139
Journal: Biomed Res Int. 2015;2015:108458.
Title: Long Noncoding RNA KIAA0125 Potentiates Cell Migration and Invasion in Gallbladder Cancer.
Author: Lv, Wenjie|Wang, Lei|Lu, Jianhua|Mu, Jiasheng|Liu, Yingbin|Dong, Ping
PMID: 26448925
Journal: Biochim Biophys Acta. 2015 Sep;1852(9):1989-99.
Title: Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression.
Author: Dutta, Suman|Reamtong, Onrapak|Panvongsa, Wittaya|Kitdumrongthum, Sarunya|Janpipatkul, Keatdamrong|Sangvanich, Polkit|Piyachaturawat, Pawinee|Chairoungdua, Arthit
PMID: 26148937
Journal: Mod Pathol. 2015 Sep;28(9):1249-64.
Title: Intraductal tubulopapillary neoplasms of the bile ducts: clinicopathologic, immunohistochemical, and molecular analysis of 20 cases.
Author: Schlitter, Anna Melissa|Jang, Kee-Taek|Kloppel, Gunter|Saka, Burcu|Hong, Seung-Mo|Choi, Hyejeong|Offerhaus, George Johan|Hruban, Ralph H|Zen, Yoh|Konukiewitz, Bjorn|Regel, Ivonne|Allgauer, Michael|Balci, Serdar|Basturk, Olca|Reid, Michelle D|Esposito, Ire
PMID: 26111977
Journal: Oncotarget. 2015 Aug 7;6(22):18905-20.
Title: Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma.
Author: Wang, Jinghan|Zhang, Keqiang|Wang, Jinhui|Wu, Xiwei|Liu, Xiyong|Li, Bin|Zhu, Yan|Yu, Yong|Cheng, Qingbao|Hu, Zhenli|Guo, Chao|Hu, Shuya|Mu, Bing|Tsai, Chun-Hao|Li, Jie|Smith, Lynne|Yang, Lu|Liu, Qi|Chu, Peiguo|Chang, Vincent|Zhang, Baihe|Wu, Mengchao|Jian
PMID: 26056085
Journal: Chem Biol Drug Des. 2015 Nov;86(5):1064-71.
Title: Long non-coding RNA Linc-ITGB1 knockdown inhibits cell migration and invasion in GBC-SD/M and GBC-SD gallbladder cancer cell lines.
Author: Wang, Lei|Zhang, Yunjiao|Lv, Wenjie|Lu, Jianhua|Mu, Jiasheng|Liu, Yingbin|Dong, Ping
PMID: 25893892
Journal: J Clin Invest. 2015 Mar 2;125(3):975-7.
Title: Moving upstream in the war on WNTs.
Author: Virshup, David M
PMID: 25689251
Journal: Chem Biol Drug Des. 2015 Oct;86(4):656-62.
Title: Downregulation of TPTE2P1 Inhibits Migration and Invasion of Gallbladder Cancer Cells.
Author: Lv, Wenjie|Wang, Lei|Lu, Jianhua|Mu, Jiasheng|Liu, Yingbin|Dong, Ping
PMID: 25676706
Journal: World J Gastroenterol. 2015 Jan 28;21(4):1148-57.
Title: beta-escin reverses multidrug resistance through inhibition of the GSK3beta/beta-catenin pathway in cholangiocarcinoma.
Author: Huang, Gui-Li|Shen, Dong-Yan|Cai, Cheng-Fu|Zhang, Qiu-Yan|Ren, Hong-Yue|Chen, Qing-Xi
PMID: 25632187
Journal: Tumour Biol. 2015 Apr;36(4):2583-91.
Title: CIZ1 promoted the growth and migration of gallbladder cancer cells.
Author: Zhang, Dexiang|Wang, Yueqi|Dai, Yuedi|Wang, Jiwen|Suo, Tao|Pan, Hongtao|Liu, Han|Shen, Sheng|Liu, Houbao
PMID: 25427641
Journal: Stem Cells. 2015 Dec;33(12):3569-80.
Title: Osteopontin Promotes Hepatic Progenitor Cell Expansion and Tumorigenicity via Activation of beta-Catenin in Mice.
Author: Liu, Yingying|Cao, Lei|Chen, Rui|Zhou, Xuyu|Fan, Xiaoyu|Liang, Yingchao|Jia, Rongjie|Wang, Hao|Liu, Guoke|Guo, Yajun|Zhao, Jian
PMID: 26033745
Journal: Gut. 2016 Oct;65(10):1765-75.
Title: LTbetaR signalling preferentially accelerates oncogenic AKT-initiated liver tumours.
Author: Scarzello, Anthony J|Jiang, Qun|Back, Timothy|Dang, Hien|Hodge, Deborah|Hanson, Charlotte|Subleski, Jeffrey|Weiss, Jonathan M|Stauffer, Jimmy K|Chaisaingmongkol, Jitti|Rabibhadana, Siritida|Ruchirawat, Mathuros|Ortaldo, John|Wang, Xin Wei|Norris, Paula S|
PMID: 26206664
Journal: Oncotarget. 2016 Jan 5;7(1):362-73.
Title: Integrin beta3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma.
Author: Yang, Sheng-Huei|Lin, Hung-Yun|Changou, Chun A|Chen, Chun-Han|Liu, Yun-Ru|Wang, Jinghan|Jiang, Xiaoqing|Luh, Frank|Yen, Yun
PMID: 26517522
Journal: Tumour Biol. 2016 Jun;37(6):8083-95.
Title: Association of Wnt signaling pathway genetic variants in gallbladder cancer susceptibility and survival.
Author: Yadav, Anu|Gupta, Annapurna|Yadav, Saurabh|Rastogi, Neeraj|Agrawal, Sushma|Kumar, Ashok|Kumar, Vijay|Misra, Sanjeev|Mittal, Balraj
PMID: 26715268
Journal: Cell Rep. 2016 Feb 2;14(4):907-19.
Title: Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation.
Author: Gingras, Marie-Claude|Covington, Kyle R|Chang, David K|Donehower, Lawrence A|Gill, Anthony J|Ittmann, Michael M|Creighton, Chad J|Johns, Amber L|Shinbrot, Eve|Dewal, Ninad|Fisher, William E|Pilarsky, Christian|Grutzmann, Robert|Overman, Michael J|Jamieson
PMID: 26804919
Journal: Eur J Histochem. 2016 Feb 9;60(1):2536.
Title: Characterizing the activation of the Wnt signaling pathway in hilar cholangiocarcinoma using a tissue microarray approach.
Author: Chen, W|Liang, J|Huang, L|Cai, J|Lei, Y|Lai, J|Liang, L|Zhang, K
PMID: 26972709
Journal: Oncotarget. 2016 Oct 25;7(43):70378-70387.
Title: Dickkopf-1 expression is associated with tumorigenity and lymphatic metastasis in human hilar cholangiocarcinoma.
Author: Shi, Xiang-de|Yu, Xian-Huan|Wu, Wen-Rui|Xu, Xiao-Lin|Wang, Jie-Yu|Xu, Lei-Bo|Zhang, Rui|Liu, Chao
PMID: 27608843
Journal: Eur J Surg Oncol. 2017 Feb;43(2):344-350.
Title: Loss of Secreted Frizzled-Related Protein-1 expression is associated with poor prognosis in intrahepatic cholangiocarcinoma.
Author: Davaadorj, M|Saito, Y|Morine, Y|Ikemoto, T|Imura, S|Takasu, C|Yamada, S|Hiroki, T|Yoshikawa, M|Shimada, M
PMID: 28062160
Journal: Pathol Res Pract. 2017 Aug;213(8):1010-1013.
Title: Adenosquamous gallbladder carcinoma: Multigene hotspot mutational profiling reveals a monoclonal origin of the two components.
Author: Galuppini, Francesca|Salmaso, Roberta|Valentini, Elisa|Lanza, Cristiano|Maretto, Isacco|Nitti, Donato|Rugge, Massimo|Fassan, Matteo
PMID: 28698100
Journal: Oncotarget. 2017 Jul 25;8(30):49897-49914.
Title: Ring finger protein 125, as a potential highly aggressive and unfavorable prognostic biomarker, promotes the invasion and metastasis of human gallbladder cancers via activating the TGF- beta1-SMAD3-ID1 signaling pathway.
Author: Liu, Zhong-Yan|Cao, Jin|Zhang, Jing-Tao|Xu, Guo-Li|Li, Xin-Ping|Wang, Fang-Tao|Ansari, Kamar Hasan|Mohamed, Hassan|Fan, Yue-Zu
PMID: 28611292
Journal: Oncotarget. 2017 May 30;8(22):36319-36330.
Title: Identification of MAP kinase pathways as therapeutic targets in gallbladder carcinoma using targeted parallel sequencing.
Author: Li, Mengdan|Chen, Lihong|Qu, Yiping|Sui, Fang|Yang, Qi|Ji, Meiju|Shi, Bingyin|Chen, Mingwei|Hou, Peng
PMID: 28422736
Journal: Cancer Control. 2018 Jan-Mar;25(1):1073274817744658.
Title: Primary Liver Cancers, Part 2: Progression Pathways and Carcinogenesis.
Author: Jiang, Kun|Centeno, Barbara A
PMID: 29353494
Journal: Biochim Biophys Acta Mol Basis Dis. 2018 Jun;1864(6 Pt B):2360-2368.
Title: Whole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversity.
Author: Liu, Zhen-Hao|Lian, Bao-Feng|Dong, Qiong-Zhu|Sun, Han|Wei, Jin-Wang|Sheng, Yuan-Yuan|Li, Wei|Li, Yi-Xue|Xie, Lu|Liu, Lei|Qin, Lun-Xiu
PMID: 29408647
Journal: Cell Death Dis. 2018 Feb 7;9(2):179.
Title: Osteopontin promotes metastasis of intrahepatic cholangiocarcinoma through recruiting MAPK1 and mediating Ser675 phosphorylation of beta-Catenin.
Author: Zheng, Yan|Zhou, Chuang|Yu, Xin-Xin|Wu, Chao|Jia, Hu-Liang|Gao, Xiao-Mei|Yang, Ji-Meng|Wang, Chao-Qun|Luo, Qin|Zhu, Ying|Zhang, Yu|Wei, Jin-Wang|Sheng, Yuan-Yuan|Dong, Qiong-Zhu|Qin, Lun-Xiu
PMID: 29415992
Journal: Am J Cancer Res. 2018 Jan 1;8(1):2-15. eCollection 2018.
Title: Genotyping and mRNA profiling reveal actionable molecular targets in biliary tract cancers.
Author: Papadopoulou, Kyriaki|Murray, Samuel|Manousou, Kyriaki|Tikas, Ioannis|Dervenis, Christos|Sgouros, Joseph|Rontogianni, Dimitra|Lakis, Sotirios|Bobos, Mattheos|Poulios, Christos|Pervana, Stavroula|Lazaridis, Georgios|Fountzilas, George|Kotoula, Vassiliki
PMID: 29416916
Journal: Cell Death Dis. 2018 Feb 14;9(2):249.
Title: Let-7c inhibits cholangiocarcinoma growth but promotes tumor cell invasion and growth at extrahepatic sites.
Author: Xie, Yu|Zhang, Hang|Guo, Xing-Jun|Feng, Ye-Chen|He, Rui-Zhi|Li, Xu|Yu, Shuo|Zhao, Yan|Shen, Ming|Zhu, Feng|Wang, Xin|Wang, Min|Balakrishnan, Asha|Ott, Michael|Peng, Feng|Qin, Ren-Yi
PMID: 29445149
Journal: Cell Death Dis. 2018 Mar 14;9(3):410.
Title: MicroRNA-30a-5p inhibits gallbladder cancer cell proliferation, migration and metastasis by targeting E2F7.
Author: Ye, Yuan-Yuan|Mei, Jia-Wei|Xiang, Shan-Shan|Li, Huai-Feng|Ma, Qiang|Song, Xiao-Ling|Wang, Zheng|Zhang, Yi-Chi|Liu, Yong-Chen|Jin, Yun-Peng|Hu, Yun-Ping|Jiang, Lin|Liu, Fa-Tao|Zhang, Yi-Jian|Hao, Ya-Juan|Liu, Ying-Bin
PMID: 29540696
Journal: Transl Oncol. 2018 Jun;11(3):585-592.
Title: Methylation-Mediated Silencing of GATA5 Gene Suppresses Cholangiocarcinoma Cell Proliferation and Metastasis.
Author: Liu, Peng|Zhou, Teng-Fei|Qiu, Bao-An|Yang, Ying-Xiang|Zhu, Yong-Jian|An, Yang|Zhao, Wen-Chao|Wu, Yin-Tao|Ma, Peng-Fei|Li, Jing-Bo|Xia, Nian-Xin
PMID: 29547757
Journal: Pathol Res Pract. 2018 Jun;214(6):835-839.
Title: MiR-21 up-regulation in ampullary adenocarcinoma and its pre-invasive lesions.
Author: Saraggi, Deborah|Galuppini, Francesca|Fanelli, Giuseppe N|Remo, Andrea|Urso, Emanuele D L|Bao, Ricardo Q|Bacchin, Deborah|Guzzardo, Vincenza|Luchini, Claudio|Braconi, Chiara|Farinati, Fabio|Rugge, Massimo|Fassan, Matteo
PMID: 29731265
Journal: Cell Physiol Biochem. 2018 Sep 20;49(5):1933-1942.
Title: miR-191 Inhibition Induces Apoptosis Through Reactivating Secreted Frizzled-Related Protein-1 in Cholangiocarcinoma.
Author: Kang, Peng-Cheng|Leng, Kai-Ming|Liu, Yue-Ping|Liu, Yang|Xu, Yi|Qin, Wei|Gao, Jian-Jun|Wang, Zhi-Dong|Tai, Sheng|Zhong, Xiang-Yu|Cui, Yun-Fu
PMID: 30235453