Primary Site >> Biliary tract Cancer
Gene >> CTNNB1
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
Ref: Expression of E-cadherin, alpha-catenin, beta-catenin, and CD44 (standard and variant isoforms) in human cholangiocarcinoma: an immunohistochemical study. PMID: 9537436 |
Ref: Beta-catenin mutations in biliary tract cancers: a population-based study in China. PMID: 11309300 Ref: Altered expression of beta-catenin without genetic mutation in intrahepatic cholangiocarcinoma. PMID: 11557787 Ref: Exogenous expression of E-cadherin in gallbladder carcinoma cell line G-415 restores its cellular polarity and differentiation. PMID: 11713577 |
Ref: The mode of tumour progression in combined hepatocellular carcinoma and cholangiocarcinoma: an immunohistochemical analysis of E-cadherin, alpha-catenin and beta-catenin. PMID: 11906618 Ref: Mutation and altered expression of beta-catenin during gallbladder carcinogenesis. PMID: 12023580 Ref: Cellular and molecular biology of biliary tract cancers. PMID: 12607585 |
Ref: Mutation analysis of K-ras and beta-catenin genes related to O6-methylguanin-DNA methyltransferase and mismatch repair protein status in human gallbladder carcinoma. PMID: 12469220 Ref: Frequent beta-catenin alteration in gallbladder carcinomas. PMID: 12866584 Ref: Alteration of the fragile histidine triad gene in intrahepatic cholangiocarcinoma. PMID: 12867802 Ref: Molecular and immunohistochemical analysis of intraductal papillary neoplasms of the biliary tract. PMID: 14562286 |
Ref: Immunohistochemical study of characteristics of bile duct dysplasia evaluated on the basis of expression of metastasis/invasion-related factors and p53. PMID: 15619017 |
Ref: Cholangiocarcinoma: molecular targeting strategies for chemoprevention and therapy. PMID: 15690474 Ref: Tumor progression through epigenetic gene silencing of O(6)-methylguanine-DNA methyltransferase in human biliary tract cancers. PMID: 15915369 Ref: Immunohistochemical and mutational analyses of Wnt signaling components and target genes in intrahepatic cholangiocarcinomas. PMID: 16142313 Ref: E-cadherin and beta-catenin expression in normal, inflamed and cancerous gallbladder tissue. PMID: 16309224 Ref: FAT, E-cadherin, beta catenin, HER 2/neu, Ki67 immuno-expression, and histological grade in intrahepatic cholangiocarcinoma. PMID: 16311342 Ref: Co-expression of cox-2, C-met and beta-catenin in cells forming invasive front of gallbladder cancer. PMID: 19956499 |
Ref: Expression of E-cadherin and beta-catenin in the adenoma-carcinoma sequence of ampulla of Vater cancer. PMID: 16506371 Ref: Intrahepatic sarcomatoid cholangiocarcinoma of round cell variant: a case report and immunohistochemical studies. PMID: 17033799 Ref: Frequent occurrence of abnormal E-cadherin/beta-catenin protein expression in advanced gallbladder cancers and its association with decreased apoptosis. PMID: 17341890 |
Ref: Bile duct cyst as precursor to biliary tract cancer. PMID: 17187167 Ref: Immunohistochemical analysis of the progression of flat and papillary preneoplastic lesions in intrahepatic cholangiocarcinogenesis in hepatolithiasis. PMID: 17919228 |
Ref: Cyclooxygenase-2-derived prostaglandin E2 activates beta-catenin in human cholangiocarcinoma cells: evidence for inhibition of these signaling pathways by omega 3 polyunsaturated fatty acids. PMID: 18199552 Ref: [The significance of immunohistochemistry in the investigation of liver neoplasms: differential diagnosis, prognostic markers]. PMID: 18942395 Ref: Morule-like features and tumor-associated lymphoid proliferation in gallbladder carcinoma. PMID: 18995208 |
Ref: A comprehensive analysis of immunohistochemical studies in intrahepatic cholangiocarcinoma using the survival tree model. PMID: 19262069 Ref: Multistep carcinogenesis of perihilar cholangiocarcinoma arising in the intrahepatic large bile ducts. PMID: 21160963 |
Ref: Tumorigenesis and phenotypic characteristics of mucin-producing bile duct tumors: an immunohistochemical approach. PMID: 19680592 Ref: Active Wnt signalling is associated with low differentiation and high proliferation in human biliary tract cancer in vitro and in vivo and is sensitive to pharmacological inhibition. PMID: 19956832 Ref: Loss of E-cadherin and beta-catenin is correlated with poor prognosis of ampullary neoplasms. PMID: 20119975 |
Ref: Xanthogranulomatous cholecystitis: a premalignant condition? PMID: 21459725 Ref: Genetics of hepatobiliary carcinogenesis. PMID: 21538283 |
Ref: Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping. PMID: 22180306 Ref: Clinicopathological significance of E-cadherin, beta-catenin and epidermal growth factor receptor expression in intrahepatic cholangiocarcinoma. PMID: 22281980 Ref: Significance of epithelial growth factor in the epithelial-mesenchymal transition of human gallbladder cancer cells. PMID: 22404757 Ref: MicroRNA-26a promotes cholangiocarcinoma growth by activating beta-catenin. PMID: 22484120 Ref: Angiotensin II enhances epithelial-to-mesenchymal transition through the interaction between activated hepatic stellate cells and the stromal cell-derived factor-1/CXCR4 axis in intrahepatic cholangiocarcinoma. PMID: 22664794 Ref: Intraductal neoplasm of the intrahepatic bile duct: clinicopathological study of 24 cases. PMID: 22851859 |
Ref: p53 and beta-catenin expression in gallbladder tissues and correlation with tumor progression in gallbladder cancer. PMID: 23319036 Ref: Suppression of cholangiocarcinoma cell growth by human umbilical cord mesenchymal stem cells: a possible role of Wnt and Akt signaling. PMID: 23646150 Ref: MiR-20a triggers metastasis of gallbladder carcinoma. PMID: 23665284 Ref: Oncogenic activity of retinoic acid receptor gamma is exhibited through activation of the Akt/NF-kappaB and Wnt/beta-catenin pathways in cholangiocarcinoma. PMID: 23798555 Ref: Inhibition of Wnt signaling induces cell apoptosis and suppresses cell proliferation in cholangiocarcinoma cells. PMID: 23799613 Ref: Inhibition of Wnt/beta-catenin signaling downregulates P-glycoprotein and reverses multi-drug resistance of cholangiocarcinoma. PMID: 23822562 Ref: Utilizing signature-score to identify oncogenic pathways of cholangiocarcinoma. PMID: 23905013 |
Ref: Intraductal papillary neoplasms of the bile duct: stepwise progression to carcinoma involves common molecular pathways. PMID: 23828315 Ref: Epithelial-mesenchymal transition phenotypes are associated with patient survival in intrahepatic cholangiocarcinoma. PMID: 24062361 Ref: Molecular factors associated with recurrence and survival following hepatectomy in patients with intrahepatic cholangiocarcinoma: a guide to adjuvant clinical trials. PMID: 24122302 Ref: GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN. PMID: 24141775 Ref: Differential expression of E-cadherin, beta-catenin, and S100A4 in intestinal type and nonintestinal type ampulla of Vater cancers. PMID: 24516707 Ref: Activated macrophages promote Wnt/beta-catenin signaling in cholangiocarcinoma cells. PMID: 24549785 Ref: The Wnt antagonist sFRP1 as a favorable prognosticator in human biliary tract carcinoma. PMID: 24594839 Ref: EGF/EGFR axis contributes to the progression of cholangiocarcinoma through the induction of an epithelial-mesenchymal transition. PMID: 24704591 Ref: Mutation profiling in gallbladder cancer in Indian population. PMID: 24739824 Ref: Comprehensive multiple molecular profile of epithelial mesenchymal transition in intrahepatic cholangiocarcinoma patients. PMID: 24816558 Ref: Loss of E-cadherin promotes migration and invasion of cholangiocarcinoma cells and serves as a potential marker of metastasis. PMID: 24867095 Ref: The role of nuclear EpICD in extrahepatic cholangiocarcinoma: association with beta-catenin. PMID: 24888903 Ref: Genomic profiling of intrahepatic cholangiocarcinoma: refining prognosis and identifying therapeutic targets. PMID: 24889489 Ref: Signet ring cell carcinoma of the ampulla of Vater: Immunophenotype and differentiation. PMID: 25202392 |
Ref: CIZ1 promoted the growth and migration of gallbladder cancer cells. PMID: 25427641 Ref: beta-escin reverses multidrug resistance through inhibition of the GSK3beta/beta-catenin pathway in cholangiocarcinoma. PMID: 25632187 Ref: Downregulation of TPTE2P1 Inhibits Migration and Invasion of Gallbladder Cancer Cells. PMID: 25676706 Ref: Moving upstream in the war on WNTs. PMID: 25689251 Ref: Long non-coding RNA Linc-ITGB1 knockdown inhibits cell migration and invasion in GBC-SD/M and GBC-SD gallbladder cancer cell lines. PMID: 25893892 Ref: Osteopontin Promotes Hepatic Progenitor Cell Expansion and Tumorigenicity via Activation of beta-Catenin in Mice. PMID: 26033745 Ref: Underexpression of LKB1 tumor suppressor is associated with enhanced Wnt signaling and malignant characteristics of human intrahepatic cholangiocarcinoma. PMID: 26056085 Ref: Intraductal tubulopapillary neoplasms of the bile ducts: clinicopathologic, immunohistochemical, and molecular analysis of 20 cases. PMID: 26111977 Ref: Proteomics profiling of cholangiocarcinoma exosomes: A potential role of oncogenic protein transferring in cancer progression. PMID: 26148937 Ref: Long Noncoding RNA KIAA0125 Potentiates Cell Migration and Invasion in Gallbladder Cancer. PMID: 26448925 Ref: miR-221 Promotes Epithelial-Mesenchymal Transition through Targeting PTEN and Forms a Positive Feedback Loop with beta-catenin/c-Jun Signaling Pathway in Extra-Hepatic Cholangiocarcinoma. PMID: 26501139 Ref: Dual role of CD44 isoforms in ampullary adenocarcinoma: CD44s predicts poor prognosis in early cancer and CD44nu is an indicator for recurrence in advanced cancer. PMID: 26572077 |
Ref: LTbetaR signalling preferentially accelerates oncogenic AKT-initiated liver tumours. PMID: 26206664 Ref: Integrin beta3 and LKB1 are independently involved in the inhibition of proliferation by lovastatin in human intrahepatic cholangiocarcinoma. PMID: 26517522 Ref: Association of Wnt signaling pathway genetic variants in gallbladder cancer susceptibility and survival. PMID: 26715268 Ref: Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation. PMID: 26804919 Ref: Characterizing the activation of the Wnt signaling pathway in hilar cholangiocarcinoma using a tissue microarray approach. PMID: 26972709 Ref: Dickkopf-1 expression is associated with tumorigenity and lymphatic metastasis in human hilar cholangiocarcinoma. PMID: 27608843 |
Ref: Loss of Secreted Frizzled-Related Protein-1 expression is associated with poor prognosis in intrahepatic cholangiocarcinoma. PMID: 28062160 Ref: Identification of MAP kinase pathways as therapeutic targets in gallbladder carcinoma using targeted parallel sequencing. PMID: 28422736 Ref: Ring finger protein 125, as a potential highly aggressive and unfavorable prognostic biomarker, promotes the invasion and metastasis of human gallbladder cancers via activating the TGF- beta1-SMAD3-ID1 signaling pathway. PMID: 28611292 Ref: Adenosquamous gallbladder carcinoma: Multigene hotspot mutational profiling reveals a monoclonal origin of the two components. PMID: 28698100 |
Ref: Primary Liver Cancers, Part 2: Progression Pathways and Carcinogenesis. PMID: 29353494 Ref: Whole-exome mutational and transcriptional landscapes of combined hepatocellular cholangiocarcinoma and intrahepatic cholangiocarcinoma reveal molecular diversity. PMID: 29408647 Ref: Osteopontin promotes metastasis of intrahepatic cholangiocarcinoma through recruiting MAPK1 and mediating Ser675 phosphorylation of beta-Catenin. PMID: 29415992 Ref: Genotyping and mRNA profiling reveal actionable molecular targets in biliary tract cancers. PMID: 29416916 Ref: Let-7c inhibits cholangiocarcinoma growth but promotes tumor cell invasion and growth at extrahepatic sites. PMID: 29445149 Ref: MicroRNA-30a-5p inhibits gallbladder cancer cell proliferation, migration and metastasis by targeting E2F7. PMID: 29540696 Ref: Methylation-Mediated Silencing of GATA5 Gene Suppresses Cholangiocarcinoma Cell Proliferation and Metastasis. PMID: 29547757 Ref: MiR-21 up-regulation in ampullary adenocarcinoma and its pre-invasive lesions. PMID: 29731265 Ref: miR-191 Inhibition Induces Apoptosis Through Reactivating Secreted Frizzled-Related Protein-1 in Cholangiocarcinoma. PMID: 30235453 |