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Journal: J Neurol. 1979 Jan 5;220(4):279-89.
Title: Cytostatic treatment of meningeal blastoses.
Author: Engelhardt, P|Lorenz, R
PMID: 90137
Journal: Cancer Immunol Immunother. 1989;29(4):288-92.
Title: Granulocyte-monocyte-colony-stimulating factor augments the cytotoxic capacity of lymphocytes and monocytes in antibody-dependent cellular cytotoxicity.
Author: Masucci, G|Wersall, P|Ragnhammar, P|Mellstedt, H
PMID: 2665935
Journal: Br J Cancer. 1990 May;61(5):749-54.
Title: Granulocyte-macrophage colony stimulating factor (GM-CSF) after high-dose melphalan in patients with advanced colon cancer.
Author: Steward, W P|Scarffe, J H|Dirix, L Y|Chang, J|Radford, J A|Bonnem, E|Crowther, D
PMID: 1692472
Journal: Biochem Pharmacol. 1990 Dec 1;40(11):2449-55.
Title: Inhibition of c-myc expression in human promyelocytic leukemia and colon adenocarcinoma cells by 6-thioguanine.
Author: Schwartz, E L|Chamberlin, H|Brechbuhl, A B
PMID: 1702632
Journal: Onkologie. 1990 Dec;13(6):437-43.
Title: Stimulation of clonal growth of human colorectal tumor cells by IL-3 and GM-CSF. Modulation of 5-FU cytotoxicity by GM-CSF.
Author: Berdel, W E|Danhauser-Riedl, S|Steinhauser, G|Rastetter, J
PMID: 2092280
Journal: J Cell Physiol. 1990 Jun;143(3):483-7.
Title: Frequent expression of receptors for granulocyte-macrophage colony-stimulating factor on human nonhematopoietic tumor cell lines.
Author: Miyagawa, K|Chiba, S|Shibuya, K|Piao, Y F|Matsuki, S|Yokota, J|Terada, M|Miyazono, K|Takaku, F
PMID: 2162848
Journal: Cancer Immunol Immunother. 1990;31(4):231-5.
Title: Granulocyte-monocyte colony-stimulating-factor augments the interleukin-2-induced cytotoxic activity of human lymphocytes in the absence and presence of mouse or chimeric monoclonal antibodies (mAb 17-1A).
Author: Masucci, G|Ragnhammar, P|Wersall, P|Mellstedt, H
PMID: 2199042
Journal: J Cell Biochem. 1991 Apr;45(4):381-90.
Title: Cytokine effects and role of adhesive proteins and Fc receptors in human macrophage-mediated antibody dependent cellular cytotoxicity.
Author: Liesveld, J L|Frediani, K E|Winslow, J M|Duerst, R E|Abboud, C N
PMID: 1675219
Journal: Acta Oncol. 1991;30(8):923-31.
Title: Therapy of colorectal carcinoma with monoclonal antibodies (MAb17-1A) alone and in combination with granulocyte monocyte-colony stimulating factor (GM-CSF).
Author: Mellstedt, H|Frodin, J E|Ragnhammar, P|Masucci, G|Ljungberg, A|Hjelm, A L|Fagerberg, J|Lindemalm, C|Osterborg, A|Wersall, P
PMID: 1777244
Journal: Med Oncol Tumor Pharmacother. 1991;8(3):207-20.
Title: Chemotherapy and immunotherapy of colorectal cancer.
Author: Masucci, G|Ragnhammar, P|Frodin, J E|Hjelm, A L|Wersall, P|Fagerberg, J|Osterborg, A|Mellstedt, H
PMID: 1803182
Journal: Urol Res. 1992;20(4):289-92.
Title: Modulation of in vitro cell growth of human and murine urothelial tumor cell lines under the influence of interleukin-3, granulocyte-, macrophage- and granulocyte-colony-stimulating factor.
Author: Block, T|Schmid, F|Geffken, B|Treiber, U|Busch, R|Hartung, R
PMID: 1380747
Journal: Cancer Immunol Immunother. 1992;35(3):158-64.
Title: Cytotoxic functions of blood mononuclear cells in patients with colorectal carcinoma treated with mAb 17-1A and granulocyte/macrophage-colony-stimulating factor.
Author: Ragnhammar, P|Masucci, G|Frodin, J E|Hjelm, A L|Mellstedt, H
PMID: 1638551
Journal: Med Oncol Tumor Pharmacother. 1993;10(1-2):61-70.
Title: The therapeutic use of the unconjugated monoclonal antibodies (MAb) 17-1A in combination with GM-CSF in the treatment of colorectal carcinoma (CRC).
Author: Ragnhammar, P|Magnusson, I|Masucci, G|Mellstedt, H
PMID: 8258997
Journal: Int J Cancer. 1993 Feb 1;53(3):426-31.
Title: Monocyte-conditioned media possess a novel factor which increases motility of cancer cells.
Author: Jiang, W G|Puntis, M C|Hallett, M B
PMID: 8428796
Journal: Int J Cancer. 1993 Mar 12;53(5):751-8.
Title: Effect of monoclonal antibody 17-1A and GM-CSF in patients with advanced colorectal carcinoma--long-lasting, complete remissions can be induced.
Author: Ragnhammar, P|Fagerberg, J|Frodin, J E|Hjelm, A L|Lindemalm, C|Magnusson, I|Masucci, G|Mellstedt, H
PMID: 8449598
Journal: Neurosurgery. 1994 Dec;35(6):1138-42; discussion 1142-3.
Title: Multifocal inflammatory leukoencephalopathy associated with levamisole and 5-fluorouracil: case report.
Author: Chen, T C|Hinton, D R|Leichman, L|Atkinson, R D|Apuzzo, M L|Couldwell, W T
PMID: 7885561
Journal: Cancer Immunol Immunother. 1994 Sep;39(3):179-84.
Title: Enhanced killing capacity of human Kupffer cells after activation with human granulocyte/macrophage-colony-stimulating factor and interferon gamma.
Author: Schuurman, B|Heuff, G|Beelen, R H|Meyer, S
PMID: 7923248
Journal: J Gastroenterol. 1994 Aug;29(4):423-9.
Title: Serum levels of cytokines in patients with colorectal cancer: possible involvement of interleukin-6 and interleukin-8 in hematogenous metastasis.
Author: Ueda, T|Shimada, E|Urakawa, T
PMID: 7951851
Journal: Invest New Drugs. 1994;12(1):49-52.
Title: FIVB plus GM-CSF in metastatic colorectal cancer.
Author: Falkson, C I|Falkson, G|Falkson, H C|Uys, A|Keren-Rosenberg, S
PMID: 7960606
Journal: Blood. 1994 Dec 15;84(12):4078-87.
Title: Induction of anti-recombinant human granulocyte-macrophage colony-stimulating factor (Escherichia coli-derived) antibodies and clinical effects in nonimmunocompromised patients.
Author: Ragnhammar, P|Friesen, H J|Frodin, J E|Lefvert, A K|Hassan, M|Osterborg, A|Mellstedt, H
PMID: 7994026
Journal: Bone Marrow Transplant. 1994 Sep;14(3):443-8.
Title: Phase I trial of high-dose melphalan, high-dose etoposide and autologous bone marrow re-infusion in solid tumors: an Eastern Cooperative Oncology Group (ECOG) study.
Author: Lazarus, H M|Gray, R|Ciobanu, N|Winter, J|Weiner, R S
PMID: 7994270
Journal: J Immunother Emphasis Tumor Immunol. 1994 Apr;15(3):217-24.
Title: Monocyte activation following systemic administration of granulocyte-macrophage colony-stimulating factor.
Author: Chachoua, A|Oratz, R|Hoogmoed, R|Caron, D|Peace, D|Liebes, L|Blum, R H|Vilcek, J
PMID: 8032545
Journal: Cancer Res. 1994 Jul 15;54(14):3700-2.
Title: Secretion of bioactive granulocyte-macrophage colony-stimulating factor by human colorectal carcinoma cells.
Author: Lahm, H|Wyniger, J|Hertig, S|Yilmaz, A|Fischer, J R|Givel, J C|Odartchenko, N
PMID: 8033086
Journal: Cancer Immunol Immunother. 1995 Jun;40(6):367-75.
Title: Granulocyte/macrophage-colony-stimulating factor augments the induction of antibodies, especially anti-idiotypic antibodies, to therapeutic monoclonal antibodies.
Author: Ragnhammar, P|Fagerberg, J|Frodin, J E|Wersall, P|Hansson, L O|Mellstedt, H
PMID: 7627993
Journal: Biochem Biophys Res Commun. 1995 Dec 5;217(1):138-43.
Title: Expression of GM-CSF and a functional GM-CSF receptor in the human colon carcinoma cell line SW403.
Author: Hirsch, T|Eggstein, S|Frank, S|Farthmann, E H|von Specht, B U
PMID: 8526901
Journal: J Biol Chem. 1995 Dec 22;270(51):30829-36.
Title: Receptors for interleukin (IL)-4 do not associate with the common gamma chain, and IL-4 induces the phosphorylation of JAK2 tyrosine kinase in human colon carcinoma cells.
Author: Murata, T|Noguchi, P D|Puri, R K
PMID: 8530527
Journal: Exp Hematol. 1996 Jan;24(1):49-53.
Title: Tumor necrosis factor administration is associated with increased endogenous production of M-CSF and G-CSF but not GM-CSF in human cancer patients.
Author: Logan, T F|Gooding, W|Kirkwood, J M|Shadduck, R K
PMID: 8536792
Journal: Eur J Immunol. 1996 Jan;26(1):1-9.
Title: Antibody-targeted superantigen therapy induces tumor-infiltrating lymphocytes, excessive cytokine production, and apoptosis in human colon carcinoma.
Author: Litton, M J|Dohlsten, M|Lando, P A|Kalland, T|Ohlsson, L|Andersson, J|Andersson, U
PMID: 8566049
Journal: Cancer Lett. 1996 Mar 29;101(2):257-61.
Title: Antitumor effect induced by the expression of granulocyte macrophage-colony stimulating factor gene in murine colon carcinoma cells.
Author: Gunji, Y|Tagawa, M|Matsubara, H|Takenaga, K|Shimada, H|Kondo, F|Suzuki, T|Nakajima, K|Sugaya, M|Asano, T|Ochiai, T|Isono, K|Horitsu, K|Kageyama, H|Nakamura, Y|Sakiyama, S
PMID: 8620478
Journal: Cancer Immunol Immunother. 1996 Feb;42(2):81-7.
Title: Humoral anti-idiotypic and anti-anti-idiotypic immune response in cancer patients treated with monoclonal antibody 17-1A.
Author: Fagerberg, J|Ragnhammar, P|Liljefors, M|Hjelm, A L|Mellstedt, H|Frodin, J E
PMID: 8620524
Journal: Clin Exp Immunol. 1996 May;104(2):351-8.
Title: Production of neutralizing granulocyte-macrophage colony-stimulating factor (GM-CSF) antibodies in carcinoma patients following GM-CSF combination therapy.
Author: Wadhwa, M|Bird, C|Fagerberg, J|Gaines-Das, R|Ragnhammar, P|Mellstedt, H|Thorpe, R
PMID: 8625532
Journal: Cancer Res. 1996 Aug 15;56(16):3758-62.
Title: Combination suicide and cytokine gene therapy for hepatic metastases of colon carcinoma: sustained antitumor immunity prolongs animal survival.
Author: Chen, S H|Kosai, K|Xu, B|Pham-Nguyen, K|Contant, C|Finegold, M J|Woo, S L
PMID: 8706021
Journal: Cancer Immunol Immunother. 1996 Jun;42(5):310-6.
Title: Effect of intraperitoneal administration of granulocyte/macrophage-colony-stimulating factor in rats on omental milky-spot composition and tumoricidal activity in vivo and in vitro.
Author: Koenen, H J|Smit, M J|Simmelink, M M|Schuurman, B|Beelen, R H|Meijer, S
PMID: 8706054
Journal: Cancer. 1996 Sep 15;78(6):1168-78.
Title: The cytokine microenvironment of human colon carcinoma. Lymphocyte expression of tumor necrosis factor-alpha and interleukin-4 predicts improved survival.
Author: Barth, R J Jr|Camp, B J|Martuscello, T A|Dain, B J|Memoli, V A
PMID: 8826937
Journal: Med Oncol. 1996 Sep;13(3):167-76.
Title: Anti-tumoral effect of GM-CSF with or without cytokines and monoclonal antibodies in solid tumors.
Author: Ragnhammar, P
PMID: 9106176
Journal: Oncology. 1997 Jan-Feb;54(1):69-73.
Title: Antitumor effect of murine colon carcinoma cells retrovirally transduced with interleukin-4 and granulocyte macrophage-colony stimulating factor genes.
Author: Gunji, Y|Tagawa, M|Matsubara, H|Takenaga, K|Shimada, H|Kondo, F|Suzuki, T|Nakajima, K|Sugaya, M|Asano, T|Ochiai, T|Isono, K|Kageyama, H|Nakamura, Y|Sakiyama, S
PMID: 8978596
Journal: Blood. 1997 Jul 1;90(1):252-9.
Title: Recombinant toxins containing human granulocyte-macrophage colony-stimulating factor and either pseudomonas exotoxin or diphtheria toxin kill gastrointestinal cancer and leukemia cells.
Author: Kreitman, R J|Pastan, I
PMID: 9207460
Journal: Int J Cancer. 1997 Aug 7;72(4):619-24.
Title: Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression in rats.
Author: Chaux, P|Favre, N|Martin, M|Martin, F
PMID: 9259401
Journal: Eur J Immunol. 1997 Sep;27(9):2375-82.
Title: Genetic modification of a carcinoma with the IL-4 gene increases the influx of dendritic cells relative to other cytokines.
Author: Stoppacciaro, A|Paglia, P|Lombardi, L|Parmiani, G|Baroni, C|Colombo, M P
PMID: 9341783
Journal: Cancer Gene Ther. 1997 Nov-Dec;4(6):339-44.
Title: Inhibition of establishment of hepatic metastasis in mice by combination gene therapy using both herpes simplex virus-thymidine kinase and granulocyte macrophage-colony stimulating factor genes in murine colon cancer.
Author: Hayashi, S|Emi, N|Yokoyama, I|Namii, Y|Uchida, K|Takagi, H
PMID: 9408603
Journal: Cancer Immunol Immunother. 1997 Nov-Dec;45(3-4):210-5.
Title: Clinical experience with CD64-directed immunotherapy. An overview.
Author: Curnow, R T
PMID: 9435876
Journal: Int J Oncol. 1998 Jan;12(1):161-70.
Title: Immunomodulatory properties of antineoplastic drugs administered in conjunction with GM-CSF-secreting cancer cell vaccines.
Author: Nigam, A|Yacavone, R F|Zahurak, M L|Johns, C M|Pardoll, D M|Piantadosi, S|Levitsky, H I|Nelson, W G
PMID: 9454900
Journal: J Exp Med. 1998 Jul 6;188(1):133-43.
Title: Interferon gamma-independent rejection of interleukin 12-transduced carcinoma cells requires CD4+ T cells and Granulocyte/Macrophage colony-stimulating factor.
Author: Zilocchi, C|Stoppacciaro, A|Chiodoni, C|Parenza, M|Terrazzini, N|Colombo, M P
PMID: 9653090
Journal: Int J Cancer. 1998 Jul 29;77(3):378-85.
Title: GM-CSF gene expression and protein production in human colorectal cancer cell lines and clinical tumor specimens.
Author: Trutmann, M|Terracciano, L|Noppen, C|Kloth, J|Kaspar, M|Peterli, R|Tondelli, P|Schaeffer, C|Zajac, P|Heberer, M|Spagnoli, G C
PMID: 9663599
Journal: Bioconjug Chem. 1998 Jul-Aug;9(4):482-9.
Title: Recombinant immunocytokines targeting the mouse transferrin receptor: construction and biological activities.
Author: Dreier, T|Lode, H N|Xiang, R|Dolman, C S|Reisfeld, R A|Kang, A S
PMID: 9667950
Journal: Cancer Immunol Immunother. 1998 Jun;46(4):213-20.
Title: The combination of interleukin-2 and interferon alpha effectively augments the antibody-dependent cellular cytotoxicity of monoclonal antibodies 17-1A and BR55-2 against the colorectal carcinoma cell line HT29.
Author: Bungard, S|Flieger, D|Schweitzer, S|Sauerbruch, T|Spengler, U
PMID: 9671144
Journal: Anticancer Res. 1998 May-Jun;18(3A):1453-6.
Title: Induction of T cell dependent acquired immunity in syngeneic mice by the combined expression of interleukin-4 and granulocyte macrophage-colony stimulating factor gene in murine colon carcinoma cells.
Author: Tasaki, K|Gunji, Y|Matsubara, H|Takenaga, K|Suzuki, T|Asano, T|Ochiai, T|Isono, K|Kouzu, T|Sakiyama, S|Tagawa, M
PMID: 9673355
Journal: Vox Sang. 1998;74 Suppl 2:489-95.
Title: Mutated Ras peptides as vaccines in immunotherapy of cancer.
Author: Gjertsen, M K|Gaudernack, G
PMID: 9704487
Journal: Clin Cancer Res. 1998 Aug;4(8):1921-9.
Title: Immunopathology of metastases in patients of colorectal carcinoma treated with monoclonal antibody 17-1A and granulocyte macrophage colony-stimulating factor.
Author: Shetye, J|Ragnhammar, P|Liljefors, M|Christensson, B|Frodin, J E|Biberfeld, P|Mellstedt, H
PMID: 9717820
Journal: Cancer Immunol Immunother. 1998 Oct;47(2):72-80.
Title: Irradiated tumor cells adenovirally engineered to secrete granulocyte/macrophage-colony-stimulating factor establish antitumor immunity and eliminate pre-existing tumors in syngeneic mice.
Author: Nagai, E|Ogawa, T|Kielian, T|Ikubo, A|Suzuki, T
PMID: 9769115
Journal: Cancer J Sci Am. 1998 Sep-Oct;4(5):331-7.
Title: Sequential phase II trials of fluorouracil and interferon beta ser with or without sargramostim in patients with advanced colorectal carcinoma.
Author: Wadler, S|Haynes, H|Rozenblit, A|Hu, X|Kaleya, R|Wiernik, P H
PMID: 9815298
Journal: Cancer Immunol Immunother. 1998 Nov;47(3):131-42.
Title: Pharmacological administration of granulocyte/macrophage-colony-stimulating factor is of significant importance for the induction of a strong humoral and cellular response in patients immunized with recombinant carcinoembryonic antigen.
Author: Samanci, A|Yi, Q|Fagerberg, J|Strigard, K|Smith, G|Ruden, U|Wahren, B|Mellstedt, H
PMID: 9829838
Journal: Cancer Treat Res. 1998;98:227-37.
Title: Biologic therapy of gastrointestinal cancer.
Author: Tempero, M
PMID: 10326671
Journal: Hybridoma. 1999 Feb;18(1):63-8.
Title: Enhancement of antibody dependent cellular cytotoxicity (ADCC) by combination of cytokines.
Author: Flieger, D|Spengler, U|Beier, I|Kleinschmidt, R|Hoff, A|Varvenne, M|Sauerbruch, T|Schmidt-Wolf, I
PMID: 10211790
Journal: Leukemia. 1999 Apr;13(4):585-9.
Title: Lack of constitutive activation of MAP kinase pathway in human acute myeloid leukemia cells with N-Ras mutation.
Author: Iida, M|Towatari, M|Nakao, A|Iida, H|Kiyoi, H|Nakano, Y|Tanimoto, M|Saito, H|Naoe, T
PMID: 10214865
Journal: Int J Cancer. 1999 Jun 11;81(6):979-84.
Title: Cytotoxic T lymphocytes define multiple peptide isoforms derived from the melanoma-associated antigen MART-1/Melan-A.
Author: Jager, E|Hohn, H|Karbach, J|Momburg, F|Castelli, C|Knuth, A|Seliger, B|Maeurer, M J
PMID: 10362148
Journal: Clin Cancer Res. 1999 Jun;5(6):1353-61.
Title: Immunogenicity of granulocyte-macrophage colony-stimulating factor (GM-CSF) products in patients undergoing combination therapy with GM-CSF.
Author: Wadhwa, M|Skog, A L|Bird, C|Ragnhammar, P|Lilljefors, M|Gaines-Das, R|Mellstedt, H|Thorpe, R
PMID: 10389919
Journal: Cancer. 1999 Jul 1;86(1):22-30.
Title: Cellular immunotherapy for patients with metastatic colorectal carcinoma using lymph node lymphocytes localized in vivo by radiolabeled monoclonal antibody.
Author: Kim, J A|Bresler, H S|Martin, E W Jr|Aldrich, W|Heffelfinger, M|Triozzi, P L
PMID: 10391559
Journal: Br J Cancer. 1999 Jan;79(1):89-94.
Title: Effect of intraperitoneally administered recombinant murine granulocyte-macrophage colony-stimulating factor (rmGM-CSF) on the cytotoxic potential of murine peritoneal cells.
Author: Klimp, A H|Regts, J|Scherphof, G L|de Vries, E G|Daemen, T
PMID: 10408698
Journal: J Exp Med. 1999 Jul 5;190(1):125-33.
Title: Dendritic cells infiltrating tumors cotransduced with granulocyte/macrophage colony-stimulating factor (GM-CSF) and CD40 ligand genes take up and present endogenous tumor-associated antigens, and prime naive mice for a cytotoxic T lymphocyte response.
Author: Chiodoni, C|Paglia, P|Stoppacciaro, A|Rodolfo, M|Parenza, M|Colombo, M P
PMID: 10429676
Journal: Immunology. 1999 Jul;97(3):526-32.
Title: Spontaneously occurring neutralizing antibodies against granulocyte-macrophage colony-stimulating factor in patients with autoimmune disease.
Author: Meager, A|Wadhwa, M|Bird, C|Dilger, P|Thorpe, R|Newsom-Davis, J|Willcox, N
PMID: 10447777
Journal: Cancer Immunol Immunother. 1999 Nov;48(8):463-70.
Title: Clinical effects of monoclonal antibody 17-1A combined with granulocyte/macrophage-colony-stimulating factor and interleukin-2 for treatment of patients with advanced colorectal carcinoma.
Author: Hjelm Skog, A|Ragnhammar, P|Fagerberg, J|Frodin, J|Goldinger, M|Koldestam, H|Liljefors, M|Nilsson, B|Shetye, J|Wersall, P|Mellstedt, H
PMID: 10550551
Journal: Br J Cancer. 1999 Nov;81(6):1009-16.
Title: Phase I clinical study applying autologous immunological effector cells transfected with the interleukin-2 gene in patients with metastatic renal cancer, colorectal cancer and lymphoma.
Author: Schmidt-Wolf, I G|Finke, S|Trojaneck, B|Denkena, A|Lefterova, P|Schwella, N|Heuft, H G|Prange, G|Korte, M|Takeya, M|Dorbic, T|Neubauer, A|Wittig, B|Huhn, D
PMID: 10576658
Journal: J Surg Oncol. 1999 Dec;72(4):218-24.
Title: Treatment of liver metastases from colon carcinoma with autologous tumor vaccine expressing granulocyte-macrophage colony-stimulating factor.
Author: Suh, K W|Piantadosi, S|Yazdi, H A|Pardoll, D M|Brem, H|Choti, M A
PMID: 10589037
Journal: Clin Immunol. 1999 Dec;93(3):209-21.
Title: Treatment with tumor necrosis factor-alpha and granulocyte-macrophage colony-stimulating factor increases epidermal Langerhans' cell numbers in cancer patients.
Author: Janik, J E|Miller, L L|Kopp, W C|Taub, D D|Dawson, H|Stevens, D|Kostboth, P|Curti, B D|Conlon, K C|Dunn, B K|Donegan, S E|Ullrich, R|Alvord, W G|Gause, B L|Longo, D L
PMID: 10600331
Journal: Bull Mem Acad R Med Belg. 1999;154(6 Pt 2):335-45.
Title: [NF-kappa B and cancers].
Author: Bours, V
PMID: 10992882
Journal: Clin Exp Metastasis. 1999;17(10):849-55.
Title: Highly metastatic variant of a mouse colon carcinoma cell line, LM17 and its response to GM-CSF gene therapy.
Author: Ikubo, A|Aoki, Y|Nagai, E|Suzuki, T
PMID: 11089883
Journal: J Immunol. 2000 Mar 1;164(5):2728-37.
Title: Induction of chemokine secretion and enhancement of contact-dependent macrophage cytotoxicity by engineered expression of granulocyte-macrophage colony-stimulating factor in human colon cancer cells.
Author: Shinohara, H|Yano, S|Bucana, C D|Fidler, I J
PMID: 10679114
Journal: Int J Cancer. 2000 Apr 15;86(2):238-43.
Title: FLT3 ligand gene expression and protein production in human colorectal cancer cell lines and clinical tumor specimens.
Author: Spagnoli, G C|Kloth, J|Terracciano, L|Trutmann, M|Chklovskaia, E|Remmel, E|Noppen, C|Zajac, P|Kocher, T|Heberer, M
PMID: 10738251
Journal: Cytokine. 2000 Jun;12(6):756-61.
Title: Combinations of the cytokines IL-12, IL-2 and IFN-alpha significantly augment whereas the cytokine IL-4 suppresses the cytokine-induced antibody-dependent cellular cytotoxicity of monoclonal antibodies 17-1A and BR55-2.
Author: Flieger, D|Spengler, U|Beier, I|Sauerbruch, T|Schmidt-Wolf, I
PMID: 10843759
Journal: Ann N Y Acad Sci. 2000 Jun;910:254-61; discussion 261-2.
Title: Ga733/EpCAM as a target for passive and active specific immunotherapy in patients with colorectal carcinoma.
Author: Mellstedt, H|Fagerberg, J|Frodin, J E|Hjelm-Skog, A L|Liljefors, M|Markovic, K|Mosolits, S|Ragnhammar, P
PMID: 10911918
Journal: Gut. 2000 Sep;47(3):343-8.
Title: Combined suicide and cytokine gene therapy for peritoneal carcinomatosis.
Author: Lechanteur, C|Delvenne, P|Princen, F|Lopez, M|Fillet, G|Gielen, J|Merville, M P|Bours, V
PMID: 10940269
Journal: Z Gastroenterol. 2000 Aug;38(8):615-22.
Title: Prestimulation of monocytes by the cytokines GM-CSF or IL-2 enhances the antibody dependent cellular cytotoxicity of monoclonal antibody 17-1A.
Author: Flieger, D|Spengler, U|Beier, I|Sauerbruch, T|Schmidt-Wolf, I G
PMID: 11031784
Journal: J Immunol. 2000 Dec 1;165(11):6278-86.
Title: Enhanced dendritic cell maturation by TNF-alpha or cytidine-phosphate-guanosine DNA drives T cell activation in vitro and therapeutic anti-tumor immune responses in vivo.
Author: Brunner, C|Seiderer, J|Schlamp, A|Bidlingmaier, M|Eigler, A|Haimerl, W|Lehr, H A|Krieg, A M|Hartmann, G|Endres, S
PMID: 11086063
Journal: Cancer Gene Ther. 2000 Dec;7(12):1519-28.
Title: Combined suicide and granulocyte-macrophage colony-stimulating factor gene therapy induces complete tumor regression and generates antitumor immunity.
Author: Jones, R K|Pope, I M|Kinsella, A R|Watson, A J|Christmas, S E
PMID: 11228530
Journal: J Submicrosc Cytol Pathol. 2000 Oct;32(4):525-33.
Title: GM-CSF expression by tumor cells correlates with aggressivity and with stroma reaction formation.
Author: Bretscher, V|Andreutti, D|Neuville, P|Martin, M|Martin, F|Lefebvre, O|Gilles, C|Benzonana, G|Gabbiani, G
PMID: 11297371
Journal: Tissue Antigens. 2001 Jan;57(1):39-45.
Title: Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines.
Author: Seliger, B|Schreiber, K|Delp, K|Meissner, M|Hammers, S|Reichert, T|Pawlischko, K|Tampe, R|Huber, C
PMID: 11169257
Journal: Oncol Rep. 2001 Mar-Apr;8(2):225-31.
Title: A clinical trial of edrecolomab, interleukin-2 and GM-CSF in patients with advanced colorectal cancer.
Author: Fiedler, W|Kruger, W|Laack, E|Mende, T|Vohwinkel, G|Hossfeld, D K
PMID: 11182031
Journal: Clin Immunol. 2001 Apr;99(1):65-74.
Title: Incidence of GM-CSF antibodies in cancer patients receiving GM-CSF for immunostimulation.
Author: Ullenhag, G|Bird, C|Ragnhammar, P|Frodin, J E|Strigard, K|OIsterborg, A|Thorpe, R|Mellstedt, H|Wadhwa, M
PMID: 11286542
Journal: Br J Surg. 2001 Apr;88(4):539-44.
Title: Immune-stimulating effects of low-dose perioperative recombinant granulocyte-macrophage colony-stimulating factor in patients operated on for primary colorectal carcinoma.
Author: Mels, A K|Statius Muller, M G|van Leeuwen, P A|von Blomberg, B M|Scheper, R J|Cuesta, M A|Beelen, R H|Meijer, S
PMID: 11298622
Journal: Clin Cancer Res. 2001 Mar;7(3 Suppl):856s-864s.
Title: Protective immunity against human carcinoembryonic antigen (CEA) induced by an oral DNA vaccine in CEA-transgenic mice.
Author: Xiang, R|Silletti, S|Lode, H N|Dolman, C S|Ruehlmann, J M|Niethammer, A G|Pertl, U|Gillies, S D|Primus, F J|Reisfeld, R A
PMID: 11300483
Journal: Inflamm Res. 2001 May;50(5):233-48.
Title: Granulocyte-colony stimulating factor in the prevention of postoperative infectious complications and sub-optimal recovery from operation in patients with colorectal cancer and increased preoperative risk (ASA 3 and 4). Protocol of a controlled clinical t
Author: Stinner, B|Bauhofer, A|Lorenz, W|Rothmund, M|Plaul, U|Torossian, A|Celik, I|Sitter, H|Koller, M|Black, A|Duda, D|Encke, A|Greger, B|van Goor, H|Hanisch, E|Hesterberg, R|Klose, K J|Lacaine, F|Lorijn, R H|Margolis, C|Neugebauer, E|Nystrom, P O|Reemst, P H|S
PMID: 11409486
Journal: Crit Rev Oncol Hematol. 2001 Jul-Aug;39(1-2):125-32.
Title: In vivo transfection and/or cross-priming of dendritic cells following DNA and adenoviral immunizations for immunotherapy of cancer--changes in peripheral mononuclear subsets and intracellular IL-4 and IFN-gamma lymphokine profile.
Author: Mincheff, M|Altankova, I|Zoubak, S|Tchakarov, S|Botev, C|Petrov, S|Krusteva, E|Kurteva, G|Kurtev, P|Dimitrov, V|Ilieva, M|Georgiev, G|Lissitchkov, T|Chernozemski, I|Meryman, H T
PMID: 11418309
Journal: Int Arch Allergy Immunol. 2001 Jul;125(3):256-63.
Title: Antitumor activity of expanded human tumor-infiltrating gammadelta T lymphocytes.
Author: Chen, J|Niu, H|He, W|Ba, D
PMID: 11490159
Journal: J Surg Res. 2001 Sep;100(1):32-8.
Title: Ex vivo host response to gastrointestinal cancer cells presented by autologous dendritic cells.
Author: Galetto, A|Contarini, M|Sapino, A|Cassoni, P|Consalvo, E|Forno, S|Pezzi, C|Barnaba, V|Mussa, A|Matera, L
PMID: 11516202
Journal: Curr Opin Mol Ther. 2001 Aug;3(4):407-12.
Title: Technology evaluation: CEA-TRICOM, Therion Biologics Corp.
Author: Morse, M A
PMID: 11525565
Journal: Br J Pharmacol. 2001 Nov;134(6):1237-44.
Title: Relationship between endogenous colony stimulating factors and apoptosis in human colon cancer cells: role of cyclo-oxygenase inhibitors.
Author: Calatayud, S|Warner, T D|Breese, E J|Mitchell, J A
PMID: 11704643
Journal: Folia Histochem Cytobiol. 2001;39 Suppl 2:110-1.
Title: Granulocyte-macrophage-colony stimulating factor in patients with colorectal cancer.
Author: Mroczko, B|Szmitkowski, M|Okulczyk, B|Piotrowski, Z
PMID: 11820563
Journal: Cancer Res. 2002 Mar 1;62(5):1364-9.
Title: Induction of IgG subclass responses in colorectal carcinoma patients vaccinated with recombinant carcinoembryonic antigen.
Author: Ullenhag, Gustav J|Frodin, Jan-Erik|Strigard, Karin|Mellstedt, Hakan|Magnusson, Carl G M
PMID: 11888906
Journal: J Immunol. 2002 Apr 1;168(7):3512-9.
Title: Tumor regression induced by intratumor therapy with a disabled infectious single cycle (DISC) herpes simplex virus (HSV) vector, DISC/HSV/murine granulocyte-macrophage colony-stimulating factor, correlates with antigen-specific adaptive immunity.
Author: Ali, Selman A|Lynam, June|McLean, Cornelia S|Entwisle, Claire|Loudon, Peter|Rojas, Jose M|McArdle, Stephanie E B|Li, Geng|Mian, Shahid|Rees, Robert C
PMID: 11907113
Journal: Cancer Biother Radiopharm. 2002 Feb;17(1):43-50.
Title: Peripheral blood immunological parameters for use as markers of pre-invasive to invasive colorectal cancer.
Author: Berghella, Anna Maria|Contasta, Ida|Pellegrini, Patrizia|Del Beato, Tiziana|Adorno, Domenico
PMID: 11915173
Journal: Hybrid Hybridomics. 2002 Apr;21(2):99-101.
Title: MAb17-1A and cytokines for the treatment of patients with colorectal carcinoma.
Author: Frodin, Jan-Erik|Fagerberg, Jan|Hjelm Skog, Anna-Lena|Liljefors, Maria|Ragnhammar, Peter|Mellstedt, Hakan
PMID: 12031098
Journal: Curr Opin Investig Drugs. 2002 Jan;3(1):140-9.
Title: Cancer vaccines, a critical review--Part I.
Author: Mitchell, Malcolm S
PMID: 12054065
Journal: Cancer Immunol Immunother. 2002 Jul;51(5):255-62.
Title: Treatment with GM-CSF and IL-2 in patients with metastatic colorectal carcinoma induced high serum levels of neopterin and sIL-2R, an indicator of immune suppression.
Author: Skog, A-L Hjelm|Wersall, P|Ragnhammar, P|Frodin, J-E|Mellstedt, Hakan
PMID: 12070712
Journal: Cancer Immunol Immunother. 2002 Aug;51(6):311-9. Epub 2002 Jun 13.
Title: Hsp110 over-expression increases the immunogenicity of the murine CT26 colon tumor.
Author: Wang, Xiang-Yang|Li, Ying|Manjili, Masoud H|Repasky, Elizabeth A|Pardoll, Drew M|Subjeck, John R
PMID: 12111119
Journal: Ann Surg. 2002 Sep;236(3):337-42; discussion 342-3.
Title: Efficacy of multiagent herpes simplex virus amplicon-mediated immunotherapy as adjuvant treatment for experimental hepatic cancer.
Author: Delman, Keith A|Zager, Jonathan S|Bennett, Joseph J|Malhotra, Sandeep|Ebright, Michael I|McAuliffe, Priscilla F|Halterman, Marc W|Federoff, Howard J|Fong, Yuman
PMID: 12192320
Journal: Cancer Chemother Pharmacol. 2002 Sep;50(3):171-8.
Title: A phase I study of the GM-CSF antagonist E21R.
Author: Olver, Ian N|Hercus, Tim|Lopez, Angel|Vadas, Matthew|Somogyi, Andrew A|Doyle, Ian|Foster, David J R|Keefe, Dorothy|Taylor, Anne|Brown, Michael|To, L Bik|Cole, Julie|Rawling, Trevor|Cambareri, Bronwyn|Myers, Melinda|Olszewski, Nancy|Bastiras, Stan|Senn, Ca
PMID: 12203098
Journal: J Immunol. 2002 Oct 1;169(7):3908-13.
Title: Critical components of a DNA fusion vaccine able to induce protective cytotoxic T cells against a single epitope of a tumor antigen.
Author: Rice, Jason|Buchan, Sarah|Stevenson, Freda K
PMID: 12244189
Journal: Int J Colorectal Dis. 2002 Nov;17(6):388-95. Epub 2002 May 8.
Title: Establishment and characterization of a rectal cancer model in mice: application to cytokine gene therapy.
Author: Chen, Yun|Chang, King-Jen|Hwang, Lih-Hwa|Chen, Chiung-Nien|Tseng, Sheng-Hong
PMID: 12355214
Journal: Cytokine. 2002 Nov 24;20(4):163-7.
Title: Modulation by colony stimulating factors of human epithelial colon cancer cell apoptosis.
Author: Calatayud, Sara|Warner, Timothy D|Breese, Emma J|Mitchell, Jane A
PMID: 12543080
Journal: J Immunol. 2003 Jan 1;170(1):99-106.
Title: OX40 ligand-transduced tumor cell vaccine synergizes with GM-CSF and requires CD40-Apc signaling to boost the host T cell antitumor response.
Author: Gri, Giorgia|Gallo, Elena|Di Carlo, Emma|Musiani, Piero|Colombo, Mario P
PMID: 12496388
Journal: Cancer Gene Ther. 2003 Mar;10(3):209-14.
Title: Dendritic cells transfected with tumor RNA for the induction of antitumor CTL in colorectal cancer.
Author: Nencioni, Alessio|Muller, Martin R|Grunebach, Frank|Garuti, Anna|Mingari, Maria C|Patrone, Franco|Ballestrero, Alberto|Brossart, Peter
PMID: 12637942
Journal: Vaccine. 2003 May 16;21(17-18):1938-47.
Title: Plasmid DNA encoding human carcinoembryonic antigen (CEA) adsorbed onto cationic microparticles induces protective immunity against colon cancer in CEA-transgenic mice.
Author: Luo, Yunping|O'Hagan, Derek|Zhou, He|Singh, Manmohan|Ulmer, Jeffrey|Reisfeld, Ralph A|James Primus, F|Xiang, Rong
PMID: 12706680
Journal: Oncology. 2003;64(4):353-60.
Title: Subcutaneous granulocyte-macrophage colony-stimulating factor in mucositis induced by an adjuvant 5-fluorouracil plus leucovorin regimen. A phase II study and review of the literature.
Author: Rossi, Antonio|Rosati, Gerardo|Colarusso, Diodoro|Manzione, Luigi
PMID: 12759532
Journal: Clin Chem Lab Med. 2003 May;41(5):646-51.
Title: Hematopoietic growth factors in colorectal cancer patients.
Author: Mroczko, Barbara|Szmitkowski, Maciej|Okulczyk, Bogna
PMID: 12812262
Journal: Clin Cancer Res. 2003 Jul;9(7):2447-56.
Title: Immunization of colorectal carcinoma patients with a recombinant canarypox virus expressing the tumor antigen Ep-CAM/KSA (ALVAC-KSA) and granulocyte macrophage colony- stimulating factor induced a tumor-specific cellular immune response.
Author: Ullenhag, Gustav J|Frodin, Jan-Erik|Mosolits, Szilvia|Kiaii, Shahryar|Hassan, Moustapha|Bonnet, Marie Claude|Moingeon, Philippe|Mellstedt, Hakan|Rabbani, Hodjattallah
PMID: 12855617
Journal: J Hematother Stem Cell Res. 2003 Jun;12(3):279-87.
Title: Infusion of unpulsed dendritic cells derived from granulocyte/macrophage colony-stimulating factor-mobilized peripheral blood CD34+ cells and monocytes in patients with advanced carcinoma.
Author: Triozzi, Pierre L|Kim, Julian|Aldrich, Wayne
PMID: 12857369
Journal: J Chemother. 2003 Aug;15(4):387-93.
Title: Immune changes in patients with colorectal cancer treated by adjuvant therapy with monoclonal antibody 17-1A: a pilot study.
Author: Tsitsilonis, O E|Tsavaris, N B|Kosmas, C|Gouveris, P|Papalambros, E
PMID: 12962368
Journal: Pol Merkur Lekarski. 2003 Nov;15(89):416-9.
Title: [Selected hematopoietic cytokines in patients with colorectal cancer].
Author: Mroczko, Barbara|Lawicki, Slawomir|Szmitkowski, Maciej|Czygier, Malgorzata|Okulczyk, Bogna|Piotrowski, Zdzislaw
PMID: 14969133
Journal: Cancer Immunol Immunother. 2004 Jan;53(1):17-25. Epub 2003 Sep 2.
Title: In situ recruitment of antigen-presenting cells by intratumoral GM-CSF gene delivery.
Author: Pan, Ping-Ying|Li, Yu|Li, Qingsheng|Gu, Pedi|Martinet, Olivier|Thung, Swan|Chen, Shu-Hsia
PMID: 12955480
Journal: Cancer Immunol Immunother. 2004 Apr;53(4):331-7.
Title: Functional HLA-DR T cell epitopes of CEA identified in patients with colorectal carcinoma immunized with the recombinant protein CEA.
Author: Ullenhag, Gustav J|Fagerberg, Jan|Strigard, Karin|Frodin, Jan-Erik|Mellstedt, Hakan
PMID: 14605762
Journal: Vaccine. 2004 Jan 26;22(5-6):773-80.
Title: Immunization of colorectal cancer patients with recombinant baculovirus-derived KSA (Ep-CAM) formulated with monophosphoryl lipid A in liposomal emulsion, with and without granulocyte-macrophage colony-stimulating factor.
Author: Neidhart, Jeffrey|Allen, Karen O|Barlow, Daunte L|Carpenter, Mark|Shaw, Denise R|Triozzi, Pierre L|Conry, Robert M
PMID: 14741172
Journal: Int J Cancer. 2004 May 1;109(5):653-60.
Title: Breast cancer cells induce osteoclast formation by stimulating host IL-11 production and downregulating granulocyte/macrophage colony-stimulating factor.
Author: Morgan, Hayley|Tumber, Anthony|Hill, Peter A
PMID: 14999770
Journal: Clin Cancer Res. 2004 May 15;10(10):3273-81.
Title: Durable carcinoembryonic antigen (CEA)-specific humoral and cellular immune responses in colorectal carcinoma patients vaccinated with recombinant CEA and granulocyte/macrophage colony-stimulating factor.
Author: Ullenhag, Gustav J|Frodin, Jan-Erik|Jeddi-Tehrani, Mahmood|Strigard, Karin|Eriksson, Emma|Samanci, Ali|Choudhury, Aniruddha|Nilsson, Bo|Rossmann, Eva D|Mosolits, Szilvia|Mellstedt, Hakan
PMID: 15161680
Journal: Clin Nucl Med. 2004 Mar;29(3):161-3.
Title: Diffuse bone marrow uptake on whole-body F-18 fluorodeoxyglucose positron emission tomography in a patient taking recombinant erythropoietin.
Author: Blodgett, Todd M|Ames, Jennifer T|Torok, Frank S|McCook, Barry M|Meltzer, Carolyn C
PMID: 15162984
Journal: Cancer Immunol Immunother. 2004 Nov;53(11):946-54. Epub 2004 Jun 4.
Title: Both soluble and membrane-bound forms of Flt3 ligand enhance tumor immunity following "suicide" gene therapy in a murine colon carcinoma model.
Author: Alsheikhly, Abdul-Razzak|Zweiri, Jehad|Walmesley, Alice J|Watson, Alastair J M|Christmas, Stephen E
PMID: 15185012
Journal: Cancer Gene Ther. 2004 Aug;11(8):570-6.
Title: Herpes simplex virus thymidine kinase and granulocyte macrophage colony-stimulating factor combination gene therapy in a murine CT26 cell colon cancer model.
Author: Lee, Ki Hyeong|Piao, Hainan|Son, Bo Ra|Heo, Dae Seog|Kim, Noe Kyeong|Kim, Seung Taik
PMID: 15232602
Journal: Int J Oncol. 2004 Sep;25(3):703-11.
Title: Anti-EpCAM monoclonal antibody (MAb17-1A) based treatment combined with alpha-interferon, 5-fluorouracil and granulocyte-macrophage colony-stimulating factor in patients with metastatic colorectal carcinoma.
Author: Liljefors, Maria|Ragnhammar, Peter|Nilsson, Bo|Ullenhag, Gustav|Mellstedt, Hakan|Frodin, Jan-Erik
PMID: 15289873
Journal: Clin Cancer Res. 2004 Aug 15;10(16):5391-402.
Title: Vaccination with Ep-CAM protein or anti-idiotypic antibody induces Th1-biased response against MHC class I- and II-restricted Ep-CAM epitopes in colorectal carcinoma patients.
Author: Mosolits, Szilvia|Markovic, Katja|Frodin, Jan-Erik|Virving, Lena|Magnusson, Carl G M|Steinitz, Michael|Fagerberg, Jan|Mellstedt, Hakan
PMID: 15328177
Journal: Cancer Immunol Immunother. 2005 Jun;54(6):557-70. Epub 2004 Nov 27.
Title: T-cell receptor BV gene usage in colorectal carcinoma patients immunised with recombinant Ep-CAM protein or anti-idiotypic antibody.
Author: Mosolits, Szilvia|Markovic, Katja|Fagerberg, Jan|Frodin, Jan-Erik|Rezvany, Mohammad-Reza|Kiaii, Shahryar|Mellstedt, Hakan|Jeddi-Tehrani, Mahmood
PMID: 15570423
Journal: Cancer Immunol Immunother. 2005 Apr;54(4):315-27. Epub 2004 Dec 11.
Title: Carcinoembryonic antigen antibody inhibits lung metastasis and augments chemotherapy in a human colonic carcinoma xenograft.
Author: Blumenthal, Rosalyn D|Osorio, Lou|Hayes, Marianne K|Horak, Ivan D|Hansen, Hans J|Goldenberg, David M
PMID: 15592930
Journal: World J Gastroenterol. 2005 Feb 7;11(5):760-3.
Title: Effect of bone marrow-derived monocytes transfected with RNA of mouse colon carcinoma on specific antitumor immunity.
Author: Chu, Xiao-Yuan|Chen, Long-Bang|Zang, Jing|Wang, Jing-Hua|Zhang, Qun|Geng, Huai-Cheng
PMID: 15655840
Journal: Int J Cancer. 2005 Jul 20;115(6):951-9.
Title: Regulation of CTL responses to MHC-restricted class I peptide of the gp70 tumour antigen by splenic parenchymal CD4+ T cells in mice failing immunotherapy with DISC-mGM-CSF.
Author: Ahmad, Murrium|Rees, Robert C|McArdle, Stephanie E|Li, Geng|Mian, Shahid|Entwisle, Claire|Loudon, Peter|Ali, Selman A
PMID: 15723299
Journal: J Surg Oncol. 2005 Mar 15;89(4):273-5.
Title: Disseminated colon cancer with severe peripheral blood eosinophilia and elevated serum levels of interleukine-2, interleukine-3, interleukine-5, and GM-CSF.
Author: Anagnostopoulos, George K|Sakorafas, George H|Kostopoulos, Panagiotis|Margantinis, George|Tsiakos, Stavros|Terpos, Evaggelos|Pavlakis, George|Fortun, Paul|Arvanitidis, Dimitrios
PMID: 15726608
Journal: Int J Oncol. 2005 Jun;26(6):1581-9.
Title: Clinical effects of a chimeric anti-EpCAM monoclonal antibody in combination with granulocyte-macrophage colony-stimulating factor in patients with metastatic colorectal carcinoma.
Author: Liljefors, Maria|Nilsson, Bo|Fagerberg, Jan|Ragnhammar, Peter|Mellstedt, Hakan|Frodin, Jan-Erik
PMID: 15870873
Journal: Magy Onkol. 2005;49(1):3-7. Epub 2005 May 18.
Title: [Activity of the National Oncology R&D Consortium in 2004].
Author: Timar, Jozsef
PMID: 15902326
Journal: J Neurooncol. 2005 Apr;72(2):185-9.
Title: Neoplastic meningitis-related encephalopathy.
Author: Chamberlain, Marc C|Tsao-Wei, Denice|Groshen, Susan
PMID: 15926000
Journal: J Surg Res. 2005 Sep;128(1):15-20.
Title: The effect of granulocyte macrophage-colony stimulating factor on bacterial translocation after administration of 5-fluorouracil in rats.
Author: Kucuk, Can|Ozkan, Metin|Akgun, Hulya|Muhtaroglu, Sebahattin|Sozuer, Erdogan
PMID: 15975592
Journal: Immunobiology. 2005;210(2-4):259-65.
Title: Therapeutic potential of Kupffer cells in prevention of liver metastases outgrowth.
Author: van der Bij, Gerben J|Oosterling, Steven J|Meijer, Sybren|Beelen, Robert H J|van Egmond, Marjolein
PMID: 16164033
Journal: Regul Pept. 2006 May 15;134(2-3):105-13.
Title: Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells.
Author: Ogunwobi, Olorunseun Olatunji|Beales, Ian L P
PMID: 16529829
Journal: World J Gastroenterol. 2006 Apr 21;12(15):2341-4.
Title: Recombinant hybrid protein, Shiga toxin and granulocyte macrophage colony stimulating factor effectively induce apoptosis of colon cancer cells.
Author: Roudkenar, Mehryar-Habibi|Bouzari, Saeid|Kuwahara, Yoshikazu|Roushandeh, Amaneh-Mohammadi|Oloomi, Mana|Fukumoto, Manabu
PMID: 16688822
Journal: Surgery. 2006 Aug;140(2):132-40.
Title: Osteopontin inhibits macrophage nitric oxide synthesis to enhance tumor proliferation.
Author: Wai, Philip Y|Guo, Luci|Gao, Chenjiang|Mi, Zhiyong|Guo, Hongtao|Kuo, Paul C
PMID: 16904962
Journal: J Exp Clin Cancer Res. 2006 Jun;25(2):201-6.
Title: Vaccination with melanoma lysate-pulsed dendritic cells, of patients with advanced colorectal carcinoma: report from a phase I study.
Author: Burgdorf, S K|Fischer, A|Claesson, M H|Kirkin, A F|Dzhandzhugazyan, K N|Rosenberg, J
PMID: 16918131
Journal: Immunobiology. 2006;211(6-8):641-9. Epub 2006 Jul 27.
Title: Preoperative granulocyte/macrophage colony-stimulating factor (GM-CSF) increases hepatic dendritic cell numbers and clustering with lymphocytes in colorectal cancer patients.
Author: Oosterling, Steven J|Mels, Anneke K|Geijtenbeek, Teunis B H|van der Bij, Gerben J|Tuk, Cornelis W|Vuylsteke, Ronald J C L M|van Leeuwen, Paul A M|Meijer, Gerrit A|Meijer, Sybren|Beelen, Robert H J|van Egmond, Marjolein
PMID: 16920503
Journal: Clin Cancer Res. 2006 Dec 15;12(24):7389-96. Epub 2006 Nov 22.
Title: A neoadjuvant/adjuvant randomized trial of colorectal cancer patients vaccinated with an anti-idiotypic antibody, 105AD7, mimicking CD55.
Author: Ullenhag, Gustav J|Spendlove, Ian|Watson, Nicholas F S|Indar, Adrian A|Dube, Mukul|Robins, Richard A|Maxwell-Armstrong, Charles|Scholefield, John H|Durrant, Lindy G
PMID: 17121873
Journal: Clin Cancer Res. 2006 Nov 15;12(22):6808-16.
Title: Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy.
Author: Li, Betty|Lalani, Alshad S|Harding, Thomas C|Luan, Bo|Koprivnikar, Kathryn|Huan Tu, Guang|Prell, Rodney|VanRoey, Melinda J|Simmons, Andrew D|Jooss, Karin
PMID: 17121902
Journal: Int J Colorectal Dis. 2007 Jan;22(1):33-8.
Title: Pretreatment serum levels of hematopoietic cytokines in patients with colorectal adenomas and cancer.
Author: Mroczko, Barbara|Szmitkowski, Maciej|Wereszczynska-Siemiatkowska, Urszula|Okulczyk, Bogna|Kedra, Boguslaw
PMID: 16520929
Journal: Int J Cancer. 2007 Feb 1;120(3):585-93.
Title: Successful cancer vaccine therapy for carcinoembryonic antigen (CEA)-expressing colon cancer using genetically modified dendritic cells that express CEA and T helper-type 1 cytokines in CEA transgenic mice.
Author: Ojima, Toshiyasu|Iwahashi, Makoto|Nakamura, Masaki|Matsuda, Kenji|Nakamori, Mikihito|Ueda, Kentaro|Naka, Teiji|Ishida, Koichiro|Primus, F James|Yamaue, Hiroki
PMID: 17096339
Journal: Vaccine. 2007 Feb 19;25(9):1607-18. Epub 2006 Nov 16.
Title: MUC1-specific immune therapy generates a strong anti-tumor response in a MUC1-tolerant colon cancer model.
Author: Mukherjee, P|Pathangey, L B|Bradley, J B|Tinder, T L|Basu, G D|Akporiaye, E T|Gendler, S J
PMID: 17166639
Journal: J Surg Oncol. 2007 Jan 1;95(1):12-21.
Title: Long term administration of granulocyte-macrophage colony stimulating factor decreases development of 1-2 dimethylhydrazine-induced colon cancer in rats.
Author: Dinc, Soykan|Ozbirecikli, Bulent|Kuru, Bekir|Gulcelik, Mehmet Ali|Ustun, Huseyin|Alagol, Haluk|Oz, Murat
PMID: 17192887
Journal: Cancer Immunol Immunother. 2007 Sep;56(9):1507-12.
Title: Long-term immunity elicited by antibody-cytokine fusion proteins protects against sequential challenge with murine mammary and colon malignancies.
Author: Helguera, Gustavo|Rodriguez, Jose A|Daniels, Tracy R|Penichet, Manuel L
PMID: 17310381
Journal: Surgery. 2007 Apr;141(4):520-9. Epub 2007 Feb 14.
Title: Use of an oncolytic virus secreting GM-CSF as combined oncolytic and immunotherapy for treatment of colorectal and hepatic adenocarcinomas.
Author: Malhotra, Sandeep|Kim, Teresa|Zager, Jonathan|Bennett, Joseph|Ebright, Michael|D'Angelica, Michael|Fong, Yuman
PMID: 17383529
Journal: Eur J Surg Oncol. 2007 Dec;33(10):1169-76. Epub 2007 May 18.
Title: Perioperative sargramostim (recombinant human GM-CSF) induces an increase in the level of soluble VEGFR1 in colon cancer patients undergoing minimally invasive surgery.
Author: Kirman, I|Belizon, A|Balik, E|Feingold, D|Arnell, T|Horst, P|Kumara, S|Cekic, V|Jain, S|Nasar, A|Whelan, R L
PMID: 17512160
Journal: World J Gastroenterol. 2007 Jun 14;13(22):3063-70.
Title: In situ tumor vaccination with adenovirus vectors encoding measles virus fusogenic membrane proteins and cytokines.
Author: Hoffmann, Dennis|Bayer, Wibke|Wildner, Oliver
PMID: 17589921
Journal: Cancer Gene Ther. 2007 Nov;14(11):918-26. Epub 2007 Aug 10.
Title: Oncolytic virotherapy with an HSV amplicon vector expressing granulocyte-macrophage colony-stimulating factor using the replication-competent HSV type 1 mutant HF10 as a helper virus.
Author: Kohno, S-I|Luo, C|Nawa, A|Fujimoto, Y|Watanabe, D|Goshima, F|Tsurumi, T|Nishiyama, Y
PMID: 17693992
Journal: Int J Mol Med. 2007 Nov;20(5):673-81.
Title: Therapeutic immune response induced by intratumoral expression of the fusogenic membrane protein of vesicular stomatitis virus and cytokines encoded by adenoviral vectors.
Author: Hoffmann, Dennis|Bayer, Wibke|Wildner, Oliver
PMID: 17912460
Journal: Cancer Immunol Immunother. 2008 Mar;57(3):379-88. Epub 2007 Aug 4.
Title: Influence of varying doses of granulocyte-macrophage colony-stimulating factor on pharmacokinetics and antibody-dependent cellular cytotoxicity.
Author: Liljefors, Maria|Nilsson, Bo|Mellstedt, Hakan|Frodin, Jan-Erik
PMID: 17676322
Journal: Prostate Cancer Prostatic Dis. 2008;11(2):187-93.
Title: Combining gene and immunotherapy for prostate cancer.
Author: Young, J G|Green, N K|Mautner, V|Searle, P F|Young, L S|James, N D
PMID: 17726452
Journal: Mol Ther. 2008 Apr;16(4):782-90.
Title: Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer.
Author: Dai, Shengming|Wei, Dong|Wu, Zhen|Zhou, Xiangyang|Wei, Xiaomou|Huang, Haixin|Li, Guisheng
PMID: 18362931
Journal: Iran Biomed J. 2008 Jan;12(1):1-6.
Title: Induction of apoptosis on K562 cell line and double strand breaks on colon cancer cell line expressing high affinity receptor for granulocyte macrophage-colony stimulating factor (GM-CSF).
Author: Roudkenar, Mehryar Habibi|Bouzari, Saeid|Kuwahara, Yoshikazu|Roushandeh, Amaneh Mohammadi|Baba, Taisuke|Oloomi, Mana|Fukumoto, Manabu
PMID: 18392089
Journal: J Chemother. 2008 Apr;20(2):278-81.
Title: Occurrence of autoimmunity in a long-term survivor with metastatic colon carcinoma treated with a new chemo-immunotherapy regimen.
Author: Correale, P|Fioravanti, A|Bertoldi, I|Montagnani, F|Miracco, C|Francini, G
PMID: 18467257
Journal: Proteomics. 2008 Aug;8(16):3342-9.
Title: Mucin-induced apoptosis of monocyte-derived dendritic cells during maturation.
Author: Ishida, Akiko|Ohta, Mariko|Toda, Munetoyo|Murata, Takeomi|Usui, Taichi|Akita, Kaoru|Inoue, Mizue|Nakada, Hiroshi
PMID: 18690650
Journal: Clin Transl Sci. 2008 Dec;1(3):263-4.
Title: Cytokine adjuvanation of therapeutic anti-tumor immunity targeted to cancer mucosa antigens.
Author: Snook, Adam E|Huang, Lan|Schulz, Stephanie|Eisenlohr, Laurence C|Waldman, Scott A
PMID: 19956776
Journal: Eur J Surg Oncol. 2009 Mar;35(3):295-301.
Title: Perioperative GMCSF limits the proangiogenic plasma protein changes associated with colorectal cancer resection.
Author: Shantha Kumara, H M C|Kirman, I|Feingold, D|Cekic, V|Nasar, A|Arnell, T|Balik, E|Hoffman, A|Baxter, R|Conte, S|Whelan, R L
PMID: 18782657
Journal: Cancer Prev Res (Phila). 2009 Jan;2(1):60-9.
Title: Inflammation-associated serum and colon markers as indicators of dietary attenuation of colon carcinogenesis in ob/ob mice.
Author: Mentor-Marcel, Roycelynn A|Bobe, Gerd|Barrett, Kathleen G|Young, Matthew R|Albert, Paul S|Bennink, Maurice R|Lanza, Elaine|Colburn, Nancy H
PMID: 19139019
Journal: Clin Cancer Res. 2009 Mar 1;15(5):1623-34.
Title: Anti-programmed death-1 synergizes with granulocyte macrophage colony-stimulating factor--secreting tumor cell immunotherapy providing therapeutic benefit to mice with established tumors.
Author: Li, Betty|VanRoey, Melinda|Wang, Changyu|Chen, Tseng-hui Timothy|Korman, Alan|Jooss, Karin
PMID: 19208793
Journal: Pathobiology. 2009;76(4):155-62.
Title: Suppression of dendritic cells by HMGB1 is associated with lymph node metastasis of human colon cancer.
Author: Kusume, Akiko|Sasahira, Tomonori|Luo, Yi|Isobe, Mamoru|Nakagawa, Naoya|Tatsumoto, Naokuni|Fujii, Kiyomu|Ohmori, Hitoshi|Kuniyasu, Hiroki
PMID: 19571604
Journal: Curr Mol Med. 2009 Jun;9(5):565-79.
Title: Role of lipoxins and resolvins as anti-inflammatory and proresolving mediators in colon cancer.
Author: Janakiram, Naveena B|Rao, Chinthalapally V
PMID: 19601807
Journal: Acta Oncol. 2009;48(8):1157-64.
Title: Changes in cytokine and biomarker blood levels in patients with colorectal cancer during dendritic cell-based vaccination.
Author: Burgdorf, Stefan K|Claesson, Mogens H|Nielsen, Hans J|Rosenberg, Jacob
PMID: 19863224
Journal: Asian Pac J Cancer Prev. 2009;10(6):1021-4.
Title: Serum granulocyte macrophage-colony stimulating factor: a tumor marker in colorectal carcinoma?
Author: Demirci, Umut|Coskun, Ugur|Sancak, Banu|Ozturk, Banu|Bahar, Burak|Benekli, Mustafa|Buyukberber, Suleyman
PMID: 20192576
Journal: Med Oncol. 2010 Sep;27(3):736-42.
Title: Tumor cell lysate-pulsed dendritic cells induce a T cell response against colon cancer in vitro and in vivo.
Author: Wu, Yu-gang|Wu, Guang-zhou|Wang, Liang|Zhang, Yan-Yun|Li, Zhong|Li, De-Chun
PMID: 19669608
Journal: Mol Ther. 2010 Apr;18(4):843-51.
Title: Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2.
Author: Morgan, Richard A|Yang, James C|Kitano, Mio|Dudley, Mark E|Laurencot, Carolyn M|Rosenberg, Steven A
PMID: 20179677
Journal: J Immunother. 2010 May;33(4):435-41.
Title: Regulatory (FoxP3+) T-cell tumor infiltration is a favorable prognostic factor in advanced colon cancer patients undergoing chemo or chemoimmunotherapy.
Author: Correale, Pierpaolo|Rotundo, Maria Saveria|Del Vecchio, Maria Teresa|Remondo, Cinzia|Migali, Cristina|Ginanneschi, Chiara|Tsang, Kwong Y|Licchetta, Antonella|Mannucci, Susanna|Loiacono, Lucia|Tassone, Pierfrancesco|Francini, Guido|Tagliaferri, Pierosandro
PMID: 20386463
Journal: Dan Med Bull. 2010 Sep;57(9):B4171.
Title: Dendritic cell vaccination of patients with metastatic colorectal cancer.
Author: Burgdorf, Stefan K
PMID: 20816019
Journal: Am J Manag Care. 2010 Sep;16(9):678-86.
Title: Colony-stimulating factor prescribing patterns in patients receiving chemotherapy for cancer.
Author: Ramsey, Scott D|McCune, Jeannine S|Blough, David K|McDermott, Cara L|Clarke, Lauren|Malin, Jennifer L|Sullivan, Sean D
PMID: 20873955
Journal: Mol Cancer. 2010 Oct 14;9:273.
Title: Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12.
Author: Rigo, Antonella|Gottardi, Michele|Zamo, Alberto|Mauri, Pierluigi|Bonifacio, Massimiliano|Krampera, Mauro|Damiani, Ernesto|Pizzolo, Giovanni|Vinante, Fabrizio
PMID: 20946648
Journal: Cytokine. 2011 Feb;53(2):243-8.
Title: The perioperative granulocyte/lymphocyte ratio is a clinically relevant marker of surgical stress in patients with colorectal cancer.
Author: Tabuchi, Takanobu|Shimazaki, Jiro|Satani, Tetsuro|Nakachi, Takeshi|Watanabe, Yoshinori|Tabuchi, Takafumi
PMID: 21094053
Journal: Vaccine. 2011 Sep 9;29(39):6817-22.
Title: A Phase I safety study of plasmid DNA immunization targeting carcinoembryonic antigen in colorectal cancer patients.
Author: Staff, Caroline|Mozaffari, Fariba|Haller, B Kristian|Wahren, Britta|Liljefors, Maria
PMID: 21195077
Journal: Ann Surg Oncol. 2011 Oct;18(10):2722-31.
Title: Intraoperative epidural analgesia prevents the early proinflammatory response to surgical trauma. Results from a prospective randomized clinical trial of intraoperative epidural versus general analgesia.
Author: Moselli, Nora Maria|Baricocchi, Elisa|Ribero, Dario|Sottile, Antonio|Suita, Luisa|Debernardi, Felicino
PMID: 21479690
Journal: J Biomed Mater Res B Appl Biomater. 2011 Oct;99(1):70-80.
Title: Synthesis and efficient hepatocyte targeting of galactosylated chitosan as a gene carrier in vitro and in vivo.
Author: Cheng, Mingrong|Li, Qing|Wan, Tao|Hong, Xiaowu|Chen, Houxiang|He, Bing|Cheng, Zhijian|Xu, Hongzhi|Ye, Tao|Zha, Bingbing|Wu, Jingbo|Zhou, Runjiao
PMID: 21656667
Journal: Blood. 2011 Aug 25;118(8):2254-65.
Title: A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells.
Author: Solito, Samantha|Falisi, Erika|Diaz-Montero, Claudia Marcela|Doni, Andrea|Pinton, Laura|Rosato, Antonio|Francescato, Samuela|Basso, Giuseppe|Zanovello, Paola|Onicescu, Georgiana|Garrett-Mayer, Elizabeth|Montero, Alberto J|Bronte, Vincenzo|Mandruzzato, Sus
PMID: 21734236
Journal: Immune Netw. 2011 Dec;11(6):383-9.
Title: Cellular Mechanism of Newly Synthesized Indoledione Derivative-induced Immunological Death of Tumor Cell.
Author: Oh, Su-Jin|Ryu, Chung-Kyu|Baek, So-Young|Lee, Hyunah
PMID: 22346779
Journal: J Clin Immunol. 2012 Aug;32(4):855-65.
Title: Induction of IgM, IgA and IgE antibodies in colorectal cancer patients vaccinated with a recombinant CEA protein.
Author: Staff, Caroline|Magnusson, Carl G M|Hojjat-Farsangi, Mohammad|Mosolits, Szilvia|Liljefors, Maria|Frodin, Jan-Erik|Wahren, Britta|Mellstedt, Hakan|Ullenhag, Gustav J
PMID: 22382876
Journal: Pharmacotherapy. 2012 Jan;32(1):7-19.
Title: Colony-stimulating factor use and impact on febrile neutropenia among patients with newly diagnosed breast, colorectal, or non-small cell lung cancer who were receiving chemotherapy.
Author: McCune, Jeannine S|Sullivan, Sean D|Blough, David K|Clarke, Lauren|McDermott, Cara|Malin, Jennifer|Ramsey, Scott
PMID: 22392824
Journal: JOP. 2012 Mar 10;13(2):166-8.
Title: Novel agents in early phase clinical studies on refractory pancreatic cancer.
Author: Strimpakos, Alexios S|Syrigos, Kostas N|Saif, Muhammad Wasif
PMID: 22406592
Journal: Biosci Biotechnol Biochem. 2012;76(4):749-54. Epub 2012 Apr 7.
Title: Attempts to express the A1-GMCSF immunotoxin in the baculovirus expression vector system.
Author: Jahanian-Najafabadi, Ali|Bouzari, Saeid|Oloomi, Mana|Roudkenar, Mehryar Habibi|Mayr, Lorenz M
PMID: 22484943
Journal: Nutr Cancer. 2012 Aug;64(6):820-5.
Title: Plasma cytokines as potential response indicators to dietary freeze-dried black raspberries in colorectal cancer patients.
Author: Mentor-Marcel, Roycelynn A|Bobe, Gerd|Sardo, Christine|Wang, Li-Shu|Kuo, Chieh-Ti|Stoner, Gary|Colburn, Nancy H
PMID: 22823889
Journal: Cancer Res. 2013 Jan 1;73(1):395-405.
Title: Immune-dependent and independent antitumor activity of GM-CSF aberrantly expressed by mouse and human colorectal tumors.
Author: Urdinguio, Rocio G|Fernandez, Agustin F|Moncada-Pazos, Angela|Huidobro, Covadonga|Rodriguez, Ramon M|Ferrero, Cecilia|Martinez-Camblor, Pablo|Obaya, Alvaro J|Bernal, Teresa|Parra-Blanco, Adolfo|Rodrigo, Luis|Santacana, Maria|Matias-Guiu, Xavier|Soldevilla
PMID: 23108143
Journal: Clin Cancer Res. 2013 Apr 1;19(7):1693-704.
Title: Increased circulation of galectin-3 in cancer induces secretion of metastasis-promoting cytokines from blood vascular endothelium.
Author: Chen, Chen|Duckworth, Carrie A|Zhao, Qicheng|Pritchard, David Mark|Rhodes, Jonathan M|Yu, Lu-Gang
PMID: 23401226
Journal: Cancer Res. 2013 Jun 15;73(12):3591-603.
Title: Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors.
Author: Duraiswamy, Jaikumar|Kaluza, Karen M|Freeman, Gordon J|Coukos, George
PMID: 23633484
Journal: Ann Surg. 2013 Dec;258(6):879-86.
Title: A randomized phase II study of immunization with dendritic cells modified with poxvectors encoding CEA and MUC1 compared with the same poxvectors plus GM-CSF for resected metastatic colorectal cancer.
Author: Morse, Michael A|Niedzwiecki, Donna|Marshall, John L|Garrett, Christopher|Chang, David Z|Aklilu, Mebea|Crocenzi, Todd S|Cole, David J|Dessureault, Sophie|Hobeika, Amy C|Osada, Takuya|Onaitis, Mark|Clary, Bryan M|Hsu, David|Devi, Gayathri R|Bulusu, Anuradh
PMID: 23657083
Journal: Cancer Lett. 2013 Aug 28;337(1):107-14.
Title: Profiles of circulating inflammatory cytokines in colorectal cancer (CRC), high cancer risk conditions, and health are distinct. Possible implications for CRC screening and surveillance.
Author: Krzystek-Korpacka, Malgorzata|Diakowska, Dorota|Kapturkiewicz, Bartosz|Bebenek, Marek|Gamian, Andrzej
PMID: 23726839
Journal: Cytokine. 2013 Oct;64(1):158-64.
Title: Circulating midkine in malignant and non-malignant colorectal diseases.
Author: Krzystek-Korpacka, Malgorzata|Diakowska, Dorota|Neubauer, Katarzyna|Gamian, Andrzej
PMID: 23899719
Journal: Onco Targets Ther. 2013 Aug 20;6:1119-27.
Title: Influence of the oncolytic parvovirus H-1, CTLA-4 antibody tremelimumab and cytostatic drugs on the human immune system in a human in vitro model of colorectal cancer cells.
Author: Heinrich, Bernd|Goepfert, Katrin|Delic, Maike|Galle, Peter R|Moehler, Markus
PMID: 23986643
Journal: PLoS One. 2013 Sep 6;8(9):e73616.
Title: Differential expression of IL-17, 22 and 23 in the progression of colorectal cancer in patients with K-ras mutation: Ras signal inhibition and crosstalk with GM-CSF and IFN-gamma.
Author: Petanidis, Savvas|Anestakis, Doxakis|Argyraki, Maria|Hadzopoulou-Cladaras, Margarita|Salifoglou, Athanasios
PMID: 24040001
Journal: Int J Mol Cell Med. 2014 Winter;3(1):27-34.
Title: Evaluation of Pre-Treatment Serum Levels of IL-7 and GM-CSF in Colorectal Cancer Patients.
Author: Taghipour Fard Ardekani, Mehdi|Malekzadeh, Mahyar|Hosseini, Seyed Vahid|Bordbar, Elahe|Doroudchi, Mehrnoosh|Ghaderi, Abbas
PMID: 24551818
Journal: Clin Cancer Res. 2014 Jun 1;20(11):2885-97.
Title: Interleukin-17A modulates circulating tumor cells in tumor draining vein of colorectal cancers and affects metastases.
Author: Tseng, Ju-Yu|Yang, Chih-Yung|Liang, Shu-Ching|Liu, Ren-Shyan|Yang, Shung-Haur|Lin, Jen-Kou|Chen, Yuh-Min|Wu, Yu-Chung|Jiang, Jeng-Kai|Lin, Chi-Hung
PMID: 24677375
Journal: PLoS One. 2014 Apr 3;9(4):e93886.
Title: Autologous tumor lysate-pulsed dendritic cell immunotherapy with cytokine-induced killer cells improves survival in gastric and colorectal cancer patients.
Author: Gao, Daiqing|Li, Changyou|Xie, Xihe|Zhao, Peng|Wei, Xiaofang|Sun, Weihong|Liu, Hsin-Chen|Alexandrou, Aris T|Jones, Jennifer|Zhao, Ronghua|Li, Jian Jian
PMID: 24699863
Journal: Hum Vaccin Immunother. 2014;10(6):1622-32.
Title: Induction of dendritic cell maturation in the skin microenvironment by soluble factors derived from colon carcinoma.
Author: Lindenberg, Jelle J|van de Ven, Rieneke|Oosterhoff, Dinja|Sombroek, Claudia C|Lougheed, Sinead M|Stam, Anita G M|Koenen, Hans J P M|van den Eertwegh, Alfons J M|Scheper, Rik J|de Gruijl, Tanja D
PMID: 24732313
Journal: Clin Cancer Res. 2014 Jun 15;20(12):3094-106.
Title: GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer.
Author: Nebiker, Christian A|Han, Junyi|Eppenberger-Castori, Serenella|Iezzi, Giandomenica|Hirt, Christian|Amicarella, Francesca|Cremonesi, Eleonora|Huber, Xaver|Padovan, Elisabetta|Angrisani, Basilio|Droeser, Raoul A|Rosso, Raffaele|Bolli, Martin|Oertli, Daniel|
PMID: 24737547
Journal: Oncoimmunology. 2014 Jan 1;3(1):e28186.
Title: GM-CSF facilitates the development of inflammation-associated colorectal carcinoma.
Author: Chen, Guojiang|Han, Gencheng|Shen, Beifen|Li, Yan
PMID: 24778929
Journal: Immunity. 2014 May 15;40(5):785-800.
Title: gammadeltaT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer.
Author: Wu, Pin|Wu, Dang|Ni, Chao|Ye, Jun|Chen, Wuzhen|Hu, Guoming|Wang, Zhen|Wang, Changrong|Zhang, Zhigang|Xia, Wenjie|Chen, Zhigang|Wang, Ke|Zhang, Tao|Xu, Jinghong|Han, Yuehua|Zhang, Ting|Wu, Xianguo|Wang, Jianwei|Gong, Weihua|Zheng, Shu|Qiu, Fuming|Yan, Jun|
PMID: 24816404
Journal: Cancer Immunol Res. 2014 Jun;2(6):568-80.
Title: TLR7 ligand augments GM-CSF-initiated antitumor immunity through activation of plasmacytoid dendritic cells.
Author: Narusawa, Megumi|Inoue, Hiroyuki|Sakamoto, Chika|Matsumura, Yumiko|Takahashi, Atsushi|Inoue, Tomoko|Watanabe, Ayumi|Miyamoto, Shohei|Miura, Yoshie|Hijikata, Yasuki|Tanaka, Yoshihiro|Inoue, Makoto|Takayama, Koichi|Okazaki, Toshihiko|Hasegawa, Mamoru|Nakani
PMID: 24830413
Journal: Ann Surg Oncol. 2014 Nov;21(12):3931-7.
Title: A safety and feasibility study of an allogeneic colon cancer cell vaccine administered with a granulocyte-macrophage colony stimulating factor-producing bystander cell line in patients with metastatic colorectal cancer.
Author: Zheng, Lei|Edil, Barish H|Soares, Kevin C|El-Shami, Khaled|Uram, Jennifer N|Judkins, Carol|Zhang, Zhe|Onners, Beth|Laheru, Daniel|Pardoll, Drew|Jaffee, Elizabeth M|Schulick, Richard D
PMID: 24943235
Journal: Anticancer Res. 2014 Jul;34(7):3481-7.
Title: Association of serum and intratumoral cytokine profiles with tumor stage and neutrophil lymphocyte ratio in colorectal cancer.
Author: Kim, Young Wan|Kim, Soo-Ki|Kim, Cheol Su|Kim, Ik Yong|Cho, Mee Yon|Kim, Nam Kyu
PMID: 24982357
Journal: J Immunol. 2014 Aug 15;193(4):2024-33.
Title: Therapy of peritoneally disseminated colon cancer by TAP-deficient embryonic stem cell-derived macrophages in allogeneic recipients.
Author: Haga, Eriko|Endo, Yuko|Haruta, Miwa|Koba, Chihiro|Matsumura, Keiko|Takamatsu, Koutaro|Ikeda, Tokunori|Nishimura, Yasuharu|Senju, Satoru
PMID: 25031460
Journal: Int J Cancer. 2015 Jan 1;136(1):127-37.
Title: Development of thyroglobulin antibodies after GVAX immunotherapy is associated with prolonged survival.
Author: De Remigis, Alessandra|de Gruijl, Tanja D|Uram, Jennifer N|Tzou, Schey-Cherng|Iwama, Shintaro|Talor, Monica V|Armstrong, Todd D|Santegoets, Saskia J A M|Slovin, Susan F|Zheng, Lei|Laheru, Daniel A|Jaffee, Elizabeth M|Gerritsen, Winald R|van den Eertwegh,
PMID: 24832153
Journal: Mol Med Rep. 2015 Mar;11(3):1877-84.
Title: Selective colorectal cancer cell lysates enhance the immune function of mature dendritic cells in vitro.
Author: Chen, Lihong|Meng, Du|Zhao, Lei|Liu, Rui|Bai, Peisong|Wang, Le|Xiao, Juxiang
PMID: 25394863
Journal: Oncotarget. 2015 May 20;6(14):12369-82.
Title: Ex vivo generation of myeloid-derived suppressor cells that model the tumor immunosuppressive environment in colorectal cancer.
Author: Dufait, Ines|Schwarze, Julia Katharina|Liechtenstein, Therese|Leonard, Wim|Jiang, Heng|Escors, David|De Ridder, Mark|Breckpot, Karine
PMID: 25869209
Journal: Cancer Biol Ther. 2015;16(5):671-7.
Title: Laparoscopic surgery for colorectal cancer is not associated with an increase in the circulating levels of several inflammation-related factors.
Author: Crucitti, Antonio|Corbi, Maddalena|Tomaiuolo, Pasquina Mc|Fanali, Caterina|Mazzari, Andrea|Lucchetti, Donatella|Migaldi, Mario|Sgambato, Alessandro
PMID: 25875151
Journal: BMC Cancer. 2015 Mar 14;15:123.
Title: Lack of significant association between serum inflammatory cytokine profiles and the presence of colorectal adenoma.
Author: Henry, Curtis J|Sedjo, Rebecca L|Rozhok, Andrii|Salstrom, Jennifer|Ahnen, Dennis|Levin, Theodore R|D'Agostino, Ralph Jr|Haffner, Steven|DeGregori, James|Byers, Tim
PMID: 25884547
Journal: J Exp Clin Cancer Res. 2015 Feb 19;34:19.
Title: Oncolytic tanapoxvirus expressing FliC causes regression of human colorectal cancer xenografts in nude mice.
Author: Conrad, Steven J|El-Aswad, Mohamed|Kurban, Esaw|Jeng, David|Tripp, Brian C|Nutting, Charles|Eversole, Robert|Mackenzie, Charles|Essani, Karim
PMID: 25887490
Journal: J Immunother. 2015 Jul-Aug;38(6):217-28.
Title: Targeting CD133high Colorectal Cancer Cells In Vitro and In Vivo With an Asymmetric Bispecific Antibody.
Author: Zhao, Lei|Yang, Yudan|Zhou, Pengfei|Ma, Hong|Zhao, Xiaolai|He, Xin|Wang, Tao|Zhang, Jing|Liu, Yang|Zhang, Tao
PMID: 26049545
Journal: Oncotarget. 2015 Aug 14;6(23):19671-84.
Title: The MUTYH base excision repair gene protects against inflammation-associated colorectal carcinogenesis.
Author: Grasso, Francesca|Di Meo, Serena|De Luca, Gabriele|Pasquini, Luca|Rossi, Stefania|Boirivant, Monica|Biffoni, Mauro|Bignami, Margherita|Di Carlo, Emma
PMID: 26109431
Journal: PLoS One. 2015 Aug 10;10(8):e0134948.
Title: Identification of Novel Biomarkers for Metastatic Colorectal Cancer Using Angiogenesis-Antibody Array and Intracellular Signaling Array.
Author: Chung, Seyung|Dwabe, Sami|Elshimali, Yayha|Sukhija, Hemlata|Aroh, Clement|Vadgama, Jaydutt V
PMID: 26258407
Journal: Photodiagnosis Photodyn Ther. 2015 Dec;12(4):598-611.
Title: The influence of ALA-mediated photodynamic therapy on secretion of selected growth factors by colon cancer cells in hypoxia-like environment in vitro.
Author: Wawrzyniec, Katarzyna|Kawczyk-Krupka, Aleksandra|Czuba, Zenon P|Krol, Wojciech|Sieron, Aleksander
PMID: 26553325
Journal: Oncolytic Virother. 2015 Jan 28;4:25-31.
Title: The emerging therapeutic potential of the oncolytic immunotherapeutic Pexa-Vec (JX-594).
Author: Breitbach, Caroline J|Bell, John C|Hwang, Tae-Ho|Kirn, David H|Burke, James
PMID: 27512667
Journal: Int J Colorectal Dis. 2016 Feb;31(2):365-75.
Title: Peritumoral adipose tissue as a source of inflammatory and angiogenic factors in colorectal cancer.
Author: Amor, S|Iglesias-de la Cruz, M C|Ferrero, E|Garcia-Villar, O|Barrios, V|Fernandez, N|Monge, L|Garcia-Villalon, A L|Granado, M
PMID: 26493186
Journal: Oncotarget. 2016 Sep 20;7(38):61562-61574.
Title: Pregnancy-specific glycoprotein 9 (PSG9), a driver for colorectal cancer, enhances angiogenesis via activation of SMAD4.
Author: Yang, Lei|Hu, Shusheng|Tan, Jinjing|Zhang, Xiaojing|Yuan, Wen|Wang, Qian|Xu, Lingling|Liu, Jian|Liu, Zheng|Jia, Yanjun|Huang, Xiaoxi
PMID: 27528036
Journal: BMC Immunol. 2016 Sep 26;17(1):31.
Title: An effective cytokine adjuvant vaccine induces autologous T-cell response against colon cancer in an animal model.
Author: Ju, Huanyu|Xing, Wenjing|Yang, Jinfeng|Zheng, Yang|Jia, Xiuzhi|Zhang, Benning|Ren, Huan
PMID: 27669687
Journal: Signal Transduct Target Ther. 2016 Nov 18;1:16025.
Title: A novel cancer vaccine with the ability to simultaneously produce anti-PD-1 antibody and GM-CSF in cancer cells and enhance Th1-biased antitumor immunity.
Author: Tian, Hongwei|Shi, Gang|Wang, Qin|Li, Yiming|Yang, Qianmei|Li, Chunlei|Yang, Guoyou|Wu, Min|Xie, Qian|Zhang, Shuang|Yang, Yang|Xiang, Rong|Yu, Dechao|Wei, Yuquan|Deng, Hongxin
PMID: 29263903
Journal: Cytokine. 2017 Jan;89:143-154.
Title: Effects of tumor vaccine expressing Granulocyte-Macrophage Colony Stimulating Factor and interleukin-18 fusion on cancer cells and its possible application for cancer immunotherapy.
Author: Lee, Sang Rok|Park, Young Kyu|Shin, Boo Ahn|Park, Hae-Ryoung
PMID: 26868088
Journal: J Leukoc Biol. 2017 Feb;101(2):367-376.
Title: Frontline Science: Coincidental null mutation of Csf2ralpha in a colony of PI3Kgamma-/- mice causes alveolar macrophage deficiency and fatal respiratory viral infection.
Author: Schneider, Christoph|Nobs, Samuel P|Heer, Alex K|Hirsch, Emilio|Penninger, Josef|Siggs, Owen M|Kopf, Manfred
PMID: 27468760
Journal: Oncoimmunology. 2017 Jan 6;6(2):e1277305.
Title: Tumor-infiltrating CD39(+)gammadeltaTregs are novel immunosuppressive T cells in human colorectal cancer.
Author: Hu, Guoming|Wu, Pin|Cheng, Pu|Zhang, Zhigang|Wang, Zhen|Yu, Xiuyan|Shao, Xuan|Wu, Dang|Ye, Jun|Zhang, Tao|Wang, Xiaochen|Qiu, Fuming|Yan, Jun|Huang, Jian
PMID: 28344891
Journal: Hum Gene Ther. 2017 Aug;28(8):667-680.
Title: An Oncolytic Adenovirus Encoding Decorin and Granulocyte Macrophage Colony Stimulating Factor Inhibits Tumor Growth in a Colorectal Tumor Model by Targeting Pro-Tumorigenic Signals and via Immune Activation.
Author: Liu, Zhao|Yang, Yuefeng|Zhang, Xiaoyan|Wang, Hao|Xu, Weidong|Wang, Hua|Xiao, Fengjun|Bai, Zhigang|Yao, Hongwei|Ma, Xuemei|Jin, Lan|Wu, Chutse|Seth, Prem|Zhang, Zhongtao|Wang, Lisheng
PMID: 28530155
Journal: Int J Immunopathol Pharmacol. 2017 Jun;30(2):152-162.
Title: MDSCs are involved in the protumorigenic potentials of GM-CSF in colitis-associated cancer.
Author: Ma, Ning|Liu, Qilin|Hou, Lin|Wang, Yalin|Liu, Ziling
PMID: 28534709
Journal: Dig Dis Sci. 2017 Aug;62(8):1977-1984.
Title: Estradiol Has Differential Effects on Acute Colonic Inflammation in the Presence and Absence of Estrogen Receptor beta Expression.
Author: Armstrong, Cameron M|Allred, Kimberly F|Weeks, Brad R|Chapkin, Robert S|Allred, Clinton D
PMID: 28573506
Journal: Sci Rep. 2017 Aug 15;7(1):8265.
Title: An epithelial-to-mesenchymal transition-inducing potential of granulocyte macrophage colony-stimulating factor in colon cancer.
Author: Chen, Yaqiong|Zhao, Zhi|Chen, Yu|Lv, Zhonglin|Ding, Xin|Wang, Renxi|Xiao, He|Hou, Chunmei|Shen, Beifen|Feng, Jiannan|Guo, Renfeng|Li, Yan|Peng, Hui|Han, Gencheng|Chen, Guojiang
PMID: 28811578
Journal: Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2017 Aug;25(4):1178-1186.
Title: [5-FU-Injured Bone Marrow Stromal Cells Initiate Stress-induced Premature Senescence of Hematopoietic Cells].
Author: Xiong, Li-Rong|Jing, Peng-Wei|Song, Xiao-Ying|Wang, Ya-Ping|Wang, Lu
PMID: 28823289
Journal: Clin Transl Immunology. 2017 Oct 6;6(10):e157.
Title: Suppression of inflammation and tissue damage by a hookworm recombinant protein in experimental colitis.
Author: Ferreira, Ivana B|Pickering, Darren A|Troy, Sally|Croese, John|Loukas, Alex|Navarro, Severine
PMID: 29114386
Journal: PeerJ. 2017 Nov 17;5:e4033.
Title: Assessment of perioperative stress in colorectal cancer by use of in vitro cell models: a systematic review.
Author: Kirkegaard, Tove|Gogenur, Mikail|Gogenur, Ismail
PMID: 29158975
Journal: Scand J Immunol. 2018 Feb;87(2):63-72.
Title: MUC1- and Survivin-based DNA Vaccine Combining Immunoadjuvants CpG and interleukin-2 in a Bicistronic Expression Plasmid Generates Specific Immune Responses and Antitumour Effects in a Murine Colorectal Carcinoma Model.
Author: Liu, C|Xie, Y|Sun, B|Geng, F|Zhang, F|Guo, Q|Wu, H|Yu, B|Wu, J|Yu, X|Kong, W|Zhang, H
PMID: 29193199
Journal: Mol Carcinog. 2018 Aug;57(8):1017-1029.
Title: PKCalpha in colon cancer cells promotes M1 macrophage polarization via MKK3/6-P38 MAPK pathway.
Author: Cheng, Yang|Zhu, Yun|Xu, Wanfu|Xu, Jiajia|Yang, Min|Chen, Peiyu|Zhao, Junhong|Geng, Lanlan|Gong, Sitang
PMID: 29637628
Journal: Carcinogenesis. 2018 Jul 3;39(7):889-899.
Title: M10, a novel derivative of Myricetin, prevents ulcerative colitis and colorectal tumor through attenuating robust endoplasmic reticulum stress.
Author: Wang, Feng|Song, Zhi-Yu|Qu, Xian-Jun|Li, Feng|Zhang, Liang|Li, Wen-Bao|Cui, Shu-Xiang
PMID: 29757351
Journal: Immunology. 2018 Oct;155(2):263-272.
Title: Tumour YAP1 and PTEN expression correlates with tumour-associated myeloid suppressor cell expansion and reduced survival in colorectal cancer.
Author: Yang, Rong|Cai, Ting-Ting|Wu, Xiao-Jun|Liu, Yi-Na|He, Jia|Zhang, Xiao-Shi|Ma, Gang|Li, Jiang
PMID: 29770434
Journal: Cytokine. 2018 Oct;110:435-441.
Title: Subsite heterogeneity in the profiles of circulating cytokines in colorectal cancer.
Author: Krzystek-Korpacka, Malgorzata|Zawadzki, Marek|Kapturkiewicz, Bartosz|Lewandowska, Paulina|Bednarz-Misa, Iwona|Gorska, Sabina|Witkiewicz, Wojciech|Gamian, Andrzej
PMID: 29801973
Journal: Clin Cancer Res. 2018 Jun 29. pii: 1078-0432.CCR-18-0125.
Title: Cancer-Stimulated CAFs Enhance Monocyte Differentiation and Protumoral TAM Activation via IL6 and GM-CSF Secretion.
Author: Cho, Haaglim|Seo, Youngha|Loke, Kin Man|Kim, Seon-Wook|Oh, Seong-Min|Kim, Jun-Hyeong|Soh, Jihee|Kim, Hyoen Sik|Lee, Hyunju|Kim, Jin|Min, Jung-Joon|Jung, Da-Woon|Williams, Darren Reece
PMID: 29959142
Journal: Front Immunol. 2018 Sep 20;9:2138.
Title: Functional Inhibitory Siglec-6 Is Upregulated in Human Colorectal Cancer-Associated Mast Cells.
Author: Yu, Yingxin|Blokhuis, Bart R J|Diks, Mara A P|Keshavarzian, Ali|Garssen, Johan|Redegeld, Frank A
PMID: 30294327