Primary Site >> Colorectal Cancer
Gene >> CSF2
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Ref: Cytostatic treatment of meningeal blastoses. PMID: 90137 |
Ref: Granulocyte-monocyte-colony-stimulating factor augments the cytotoxic capacity of lymphocytes and monocytes in antibody-dependent cellular cytotoxicity. PMID: 2665935 |
Ref: Granulocyte-macrophage colony stimulating factor (GM-CSF) after high-dose melphalan in patients with advanced colon cancer. PMID: 1692472 Ref: Inhibition of c-myc expression in human promyelocytic leukemia and colon adenocarcinoma cells by 6-thioguanine. PMID: 1702632 Ref: Stimulation of clonal growth of human colorectal tumor cells by IL-3 and GM-CSF. Modulation of 5-FU cytotoxicity by GM-CSF. PMID: 2092280 Ref: Frequent expression of receptors for granulocyte-macrophage colony-stimulating factor on human nonhematopoietic tumor cell lines. PMID: 2162848 Ref: Granulocyte-monocyte colony-stimulating-factor augments the interleukin-2-induced cytotoxic activity of human lymphocytes in the absence and presence of mouse or chimeric monoclonal antibodies (mAb 17-1A). PMID: 2199042 |
Ref: Cytokine effects and role of adhesive proteins and Fc receptors in human macrophage-mediated antibody dependent cellular cytotoxicity. PMID: 1675219 Ref: Therapy of colorectal carcinoma with monoclonal antibodies (MAb17-1A) alone and in combination with granulocyte monocyte-colony stimulating factor (GM-CSF). PMID: 1777244 Ref: Chemotherapy and immunotherapy of colorectal cancer. PMID: 1803182 |
Ref: Modulation of in vitro cell growth of human and murine urothelial tumor cell lines under the influence of interleukin-3, granulocyte-, macrophage- and granulocyte-colony-stimulating factor. PMID: 1380747 Ref: Cytotoxic functions of blood mononuclear cells in patients with colorectal carcinoma treated with mAb 17-1A and granulocyte/macrophage-colony-stimulating factor. PMID: 1638551 |
Ref: The therapeutic use of the unconjugated monoclonal antibodies (MAb) 17-1A in combination with GM-CSF in the treatment of colorectal carcinoma (CRC). PMID: 8258997 Ref: Monocyte-conditioned media possess a novel factor which increases motility of cancer cells. PMID: 8428796 Ref: Effect of monoclonal antibody 17-1A and GM-CSF in patients with advanced colorectal carcinoma--long-lasting, complete remissions can be induced. PMID: 8449598 |
Ref: Multifocal inflammatory leukoencephalopathy associated with levamisole and 5-fluorouracil: case report. PMID: 7885561 Ref: Enhanced killing capacity of human Kupffer cells after activation with human granulocyte/macrophage-colony-stimulating factor and interferon gamma. PMID: 7923248 Ref: Serum levels of cytokines in patients with colorectal cancer: possible involvement of interleukin-6 and interleukin-8 in hematogenous metastasis. PMID: 7951851 Ref: FIVB plus GM-CSF in metastatic colorectal cancer. PMID: 7960606 Ref: Induction of anti-recombinant human granulocyte-macrophage colony-stimulating factor (Escherichia coli-derived) antibodies and clinical effects in nonimmunocompromised patients. PMID: 7994026 Ref: Phase I trial of high-dose melphalan, high-dose etoposide and autologous bone marrow re-infusion in solid tumors: an Eastern Cooperative Oncology Group (ECOG) study. PMID: 7994270 Ref: Monocyte activation following systemic administration of granulocyte-macrophage colony-stimulating factor. PMID: 8032545 Ref: Secretion of bioactive granulocyte-macrophage colony-stimulating factor by human colorectal carcinoma cells. PMID: 8033086 |
Ref: Granulocyte/macrophage-colony-stimulating factor augments the induction of antibodies, especially anti-idiotypic antibodies, to therapeutic monoclonal antibodies. PMID: 7627993 Ref: Expression of GM-CSF and a functional GM-CSF receptor in the human colon carcinoma cell line SW403. PMID: 8526901 Ref: Receptors for interleukin (IL)-4 do not associate with the common gamma chain, and IL-4 induces the phosphorylation of JAK2 tyrosine kinase in human colon carcinoma cells. PMID: 8530527 |
Ref: Tumor necrosis factor administration is associated with increased endogenous production of M-CSF and G-CSF but not GM-CSF in human cancer patients. PMID: 8536792 Ref: Antibody-targeted superantigen therapy induces tumor-infiltrating lymphocytes, excessive cytokine production, and apoptosis in human colon carcinoma. PMID: 8566049 Ref: Antitumor effect induced by the expression of granulocyte macrophage-colony stimulating factor gene in murine colon carcinoma cells. PMID: 8620478 Ref: Humoral anti-idiotypic and anti-anti-idiotypic immune response in cancer patients treated with monoclonal antibody 17-1A. PMID: 8620524 Ref: Production of neutralizing granulocyte-macrophage colony-stimulating factor (GM-CSF) antibodies in carcinoma patients following GM-CSF combination therapy. PMID: 8625532 Ref: Combination suicide and cytokine gene therapy for hepatic metastases of colon carcinoma: sustained antitumor immunity prolongs animal survival. PMID: 8706021 Ref: Effect of intraperitoneal administration of granulocyte/macrophage-colony-stimulating factor in rats on omental milky-spot composition and tumoricidal activity in vivo and in vitro. PMID: 8706054 Ref: The cytokine microenvironment of human colon carcinoma. Lymphocyte expression of tumor necrosis factor-alpha and interleukin-4 predicts improved survival. PMID: 8826937 Ref: Anti-tumoral effect of GM-CSF with or without cytokines and monoclonal antibodies in solid tumors. PMID: 9106176 |
Ref: Antitumor effect of murine colon carcinoma cells retrovirally transduced with interleukin-4 and granulocyte macrophage-colony stimulating factor genes. PMID: 8978596 Ref: Recombinant toxins containing human granulocyte-macrophage colony-stimulating factor and either pseudomonas exotoxin or diphtheria toxin kill gastrointestinal cancer and leukemia cells. PMID: 9207460 Ref: Tumor-infiltrating dendritic cells are defective in their antigen-presenting function and inducible B7 expression in rats. PMID: 9259401 Ref: Genetic modification of a carcinoma with the IL-4 gene increases the influx of dendritic cells relative to other cytokines. PMID: 9341783 Ref: Inhibition of establishment of hepatic metastasis in mice by combination gene therapy using both herpes simplex virus-thymidine kinase and granulocyte macrophage-colony stimulating factor genes in murine colon cancer. PMID: 9408603 Ref: Clinical experience with CD64-directed immunotherapy. An overview. PMID: 9435876 |
Ref: Immunomodulatory properties of antineoplastic drugs administered in conjunction with GM-CSF-secreting cancer cell vaccines. PMID: 9454900 Ref: Interferon gamma-independent rejection of interleukin 12-transduced carcinoma cells requires CD4+ T cells and Granulocyte/Macrophage colony-stimulating factor. PMID: 9653090 Ref: GM-CSF gene expression and protein production in human colorectal cancer cell lines and clinical tumor specimens. PMID: 9663599 Ref: Recombinant immunocytokines targeting the mouse transferrin receptor: construction and biological activities. PMID: 9667950 Ref: The combination of interleukin-2 and interferon alpha effectively augments the antibody-dependent cellular cytotoxicity of monoclonal antibodies 17-1A and BR55-2 against the colorectal carcinoma cell line HT29. PMID: 9671144 Ref: Induction of T cell dependent acquired immunity in syngeneic mice by the combined expression of interleukin-4 and granulocyte macrophage-colony stimulating factor gene in murine colon carcinoma cells. PMID: 9673355 Ref: Mutated Ras peptides as vaccines in immunotherapy of cancer. PMID: 9704487 Ref: Immunopathology of metastases in patients of colorectal carcinoma treated with monoclonal antibody 17-1A and granulocyte macrophage colony-stimulating factor. PMID: 9717820 Ref: Irradiated tumor cells adenovirally engineered to secrete granulocyte/macrophage-colony-stimulating factor establish antitumor immunity and eliminate pre-existing tumors in syngeneic mice. PMID: 9769115 Ref: Sequential phase II trials of fluorouracil and interferon beta ser with or without sargramostim in patients with advanced colorectal carcinoma. PMID: 9815298 Ref: Pharmacological administration of granulocyte/macrophage-colony-stimulating factor is of significant importance for the induction of a strong humoral and cellular response in patients immunized with recombinant carcinoembryonic antigen. PMID: 9829838 Ref: Biologic therapy of gastrointestinal cancer. PMID: 10326671 |
Ref: Enhancement of antibody dependent cellular cytotoxicity (ADCC) by combination of cytokines. PMID: 10211790 Ref: Lack of constitutive activation of MAP kinase pathway in human acute myeloid leukemia cells with N-Ras mutation. PMID: 10214865 Ref: Cytotoxic T lymphocytes define multiple peptide isoforms derived from the melanoma-associated antigen MART-1/Melan-A. PMID: 10362148 Ref: Immunogenicity of granulocyte-macrophage colony-stimulating factor (GM-CSF) products in patients undergoing combination therapy with GM-CSF. PMID: 10389919 Ref: Cellular immunotherapy for patients with metastatic colorectal carcinoma using lymph node lymphocytes localized in vivo by radiolabeled monoclonal antibody. PMID: 10391559 Ref: Effect of intraperitoneally administered recombinant murine granulocyte-macrophage colony-stimulating factor (rmGM-CSF) on the cytotoxic potential of murine peritoneal cells. PMID: 10408698 Ref: Dendritic cells infiltrating tumors cotransduced with granulocyte/macrophage colony-stimulating factor (GM-CSF) and CD40 ligand genes take up and present endogenous tumor-associated antigens, and prime naive mice for a cytotoxic T lymphocyte response. PMID: 10429676 Ref: Spontaneously occurring neutralizing antibodies against granulocyte-macrophage colony-stimulating factor in patients with autoimmune disease. PMID: 10447777 Ref: Clinical effects of monoclonal antibody 17-1A combined with granulocyte/macrophage-colony-stimulating factor and interleukin-2 for treatment of patients with advanced colorectal carcinoma. PMID: 10550551 Ref: Phase I clinical study applying autologous immunological effector cells transfected with the interleukin-2 gene in patients with metastatic renal cancer, colorectal cancer and lymphoma. PMID: 10576658 Ref: Treatment of liver metastases from colon carcinoma with autologous tumor vaccine expressing granulocyte-macrophage colony-stimulating factor. PMID: 10589037 Ref: Treatment with tumor necrosis factor-alpha and granulocyte-macrophage colony-stimulating factor increases epidermal Langerhans' cell numbers in cancer patients. PMID: 10600331 Ref: [NF-kappa B and cancers]. PMID: 10992882 Ref: Highly metastatic variant of a mouse colon carcinoma cell line, LM17 and its response to GM-CSF gene therapy. PMID: 11089883 |
Ref: Induction of chemokine secretion and enhancement of contact-dependent macrophage cytotoxicity by engineered expression of granulocyte-macrophage colony-stimulating factor in human colon cancer cells. PMID: 10679114 Ref: FLT3 ligand gene expression and protein production in human colorectal cancer cell lines and clinical tumor specimens. PMID: 10738251 Ref: Combinations of the cytokines IL-12, IL-2 and IFN-alpha significantly augment whereas the cytokine IL-4 suppresses the cytokine-induced antibody-dependent cellular cytotoxicity of monoclonal antibodies 17-1A and BR55-2. PMID: 10843759 Ref: Ga733/EpCAM as a target for passive and active specific immunotherapy in patients with colorectal carcinoma. PMID: 10911918 Ref: Combined suicide and cytokine gene therapy for peritoneal carcinomatosis. PMID: 10940269 Ref: Prestimulation of monocytes by the cytokines GM-CSF or IL-2 enhances the antibody dependent cellular cytotoxicity of monoclonal antibody 17-1A. PMID: 11031784 Ref: Enhanced dendritic cell maturation by TNF-alpha or cytidine-phosphate-guanosine DNA drives T cell activation in vitro and therapeutic anti-tumor immune responses in vivo. PMID: 11086063 Ref: Combined suicide and granulocyte-macrophage colony-stimulating factor gene therapy induces complete tumor regression and generates antitumor immunity. PMID: 11228530 Ref: GM-CSF expression by tumor cells correlates with aggressivity and with stroma reaction formation. PMID: 11297371 |
Ref: Downregulation of the constitutive tapasin expression in human tumor cells of distinct origin and its transcriptional upregulation by cytokines. PMID: 11169257 Ref: A clinical trial of edrecolomab, interleukin-2 and GM-CSF in patients with advanced colorectal cancer. PMID: 11182031 Ref: Incidence of GM-CSF antibodies in cancer patients receiving GM-CSF for immunostimulation. PMID: 11286542 Ref: Immune-stimulating effects of low-dose perioperative recombinant granulocyte-macrophage colony-stimulating factor in patients operated on for primary colorectal carcinoma. PMID: 11298622 Ref: Protective immunity against human carcinoembryonic antigen (CEA) induced by an oral DNA vaccine in CEA-transgenic mice. PMID: 11300483 Ref: Granulocyte-colony stimulating factor in the prevention of postoperative infectious complications and sub-optimal recovery from operation in patients with colorectal cancer and increased preoperative risk (ASA 3 and 4). Protocol of a controlled clinical t PMID: 11409486 Ref: In vivo transfection and/or cross-priming of dendritic cells following DNA and adenoviral immunizations for immunotherapy of cancer--changes in peripheral mononuclear subsets and intracellular IL-4 and IFN-gamma lymphokine profile. PMID: 11418309 Ref: Antitumor activity of expanded human tumor-infiltrating gammadelta T lymphocytes. PMID: 11490159 Ref: Ex vivo host response to gastrointestinal cancer cells presented by autologous dendritic cells. PMID: 11516202 Ref: Technology evaluation: CEA-TRICOM, Therion Biologics Corp. PMID: 11525565 Ref: Relationship between endogenous colony stimulating factors and apoptosis in human colon cancer cells: role of cyclo-oxygenase inhibitors. PMID: 11704643 Ref: Granulocyte-macrophage-colony stimulating factor in patients with colorectal cancer. PMID: 11820563 |
Ref: Induction of IgG subclass responses in colorectal carcinoma patients vaccinated with recombinant carcinoembryonic antigen. PMID: 11888906 Ref: Tumor regression induced by intratumor therapy with a disabled infectious single cycle (DISC) herpes simplex virus (HSV) vector, DISC/HSV/murine granulocyte-macrophage colony-stimulating factor, correlates with antigen-specific adaptive immunity. PMID: 11907113 Ref: Peripheral blood immunological parameters for use as markers of pre-invasive to invasive colorectal cancer. PMID: 11915173 Ref: MAb17-1A and cytokines for the treatment of patients with colorectal carcinoma. PMID: 12031098 Ref: Cancer vaccines, a critical review--Part I. PMID: 12054065 Ref: Treatment with GM-CSF and IL-2 in patients with metastatic colorectal carcinoma induced high serum levels of neopterin and sIL-2R, an indicator of immune suppression. PMID: 12070712 Ref: Hsp110 over-expression increases the immunogenicity of the murine CT26 colon tumor. PMID: 12111119 Ref: Efficacy of multiagent herpes simplex virus amplicon-mediated immunotherapy as adjuvant treatment for experimental hepatic cancer. PMID: 12192320 Ref: A phase I study of the GM-CSF antagonist E21R. PMID: 12203098 Ref: Critical components of a DNA fusion vaccine able to induce protective cytotoxic T cells against a single epitope of a tumor antigen. PMID: 12244189 Ref: Establishment and characterization of a rectal cancer model in mice: application to cytokine gene therapy. PMID: 12355214 Ref: Modulation by colony stimulating factors of human epithelial colon cancer cell apoptosis. PMID: 12543080 |
Ref: OX40 ligand-transduced tumor cell vaccine synergizes with GM-CSF and requires CD40-Apc signaling to boost the host T cell antitumor response. PMID: 12496388 Ref: Dendritic cells transfected with tumor RNA for the induction of antitumor CTL in colorectal cancer. PMID: 12637942 Ref: Plasmid DNA encoding human carcinoembryonic antigen (CEA) adsorbed onto cationic microparticles induces protective immunity against colon cancer in CEA-transgenic mice. PMID: 12706680 Ref: Subcutaneous granulocyte-macrophage colony-stimulating factor in mucositis induced by an adjuvant 5-fluorouracil plus leucovorin regimen. A phase II study and review of the literature. PMID: 12759532 Ref: Hematopoietic growth factors in colorectal cancer patients. PMID: 12812262 Ref: Immunization of colorectal carcinoma patients with a recombinant canarypox virus expressing the tumor antigen Ep-CAM/KSA (ALVAC-KSA) and granulocyte macrophage colony- stimulating factor induced a tumor-specific cellular immune response. PMID: 12855617 Ref: Infusion of unpulsed dendritic cells derived from granulocyte/macrophage colony-stimulating factor-mobilized peripheral blood CD34+ cells and monocytes in patients with advanced carcinoma. PMID: 12857369 Ref: Immune changes in patients with colorectal cancer treated by adjuvant therapy with monoclonal antibody 17-1A: a pilot study. PMID: 12962368 Ref: [Selected hematopoietic cytokines in patients with colorectal cancer]. PMID: 14969133 |
Ref: In situ recruitment of antigen-presenting cells by intratumoral GM-CSF gene delivery. PMID: 12955480 Ref: Functional HLA-DR T cell epitopes of CEA identified in patients with colorectal carcinoma immunized with the recombinant protein CEA. PMID: 14605762 Ref: Immunization of colorectal cancer patients with recombinant baculovirus-derived KSA (Ep-CAM) formulated with monophosphoryl lipid A in liposomal emulsion, with and without granulocyte-macrophage colony-stimulating factor. PMID: 14741172 Ref: Breast cancer cells induce osteoclast formation by stimulating host IL-11 production and downregulating granulocyte/macrophage colony-stimulating factor. PMID: 14999770 Ref: Durable carcinoembryonic antigen (CEA)-specific humoral and cellular immune responses in colorectal carcinoma patients vaccinated with recombinant CEA and granulocyte/macrophage colony-stimulating factor. PMID: 15161680 Ref: Diffuse bone marrow uptake on whole-body F-18 fluorodeoxyglucose positron emission tomography in a patient taking recombinant erythropoietin. PMID: 15162984 Ref: Both soluble and membrane-bound forms of Flt3 ligand enhance tumor immunity following "suicide" gene therapy in a murine colon carcinoma model. PMID: 15185012 Ref: Herpes simplex virus thymidine kinase and granulocyte macrophage colony-stimulating factor combination gene therapy in a murine CT26 cell colon cancer model. PMID: 15232602 Ref: Anti-EpCAM monoclonal antibody (MAb17-1A) based treatment combined with alpha-interferon, 5-fluorouracil and granulocyte-macrophage colony-stimulating factor in patients with metastatic colorectal carcinoma. PMID: 15289873 Ref: Vaccination with Ep-CAM protein or anti-idiotypic antibody induces Th1-biased response against MHC class I- and II-restricted Ep-CAM epitopes in colorectal carcinoma patients. PMID: 15328177 |
Ref: T-cell receptor BV gene usage in colorectal carcinoma patients immunised with recombinant Ep-CAM protein or anti-idiotypic antibody. PMID: 15570423 Ref: Carcinoembryonic antigen antibody inhibits lung metastasis and augments chemotherapy in a human colonic carcinoma xenograft. PMID: 15592930 Ref: Effect of bone marrow-derived monocytes transfected with RNA of mouse colon carcinoma on specific antitumor immunity. PMID: 15655840 Ref: Regulation of CTL responses to MHC-restricted class I peptide of the gp70 tumour antigen by splenic parenchymal CD4+ T cells in mice failing immunotherapy with DISC-mGM-CSF. PMID: 15723299 Ref: Disseminated colon cancer with severe peripheral blood eosinophilia and elevated serum levels of interleukine-2, interleukine-3, interleukine-5, and GM-CSF. PMID: 15726608 Ref: Clinical effects of a chimeric anti-EpCAM monoclonal antibody in combination with granulocyte-macrophage colony-stimulating factor in patients with metastatic colorectal carcinoma. PMID: 15870873 Ref: [Activity of the National Oncology R&D Consortium in 2004]. PMID: 15902326 Ref: Neoplastic meningitis-related encephalopathy. PMID: 15926000 Ref: The effect of granulocyte macrophage-colony stimulating factor on bacterial translocation after administration of 5-fluorouracil in rats. PMID: 15975592 Ref: Therapeutic potential of Kupffer cells in prevention of liver metastases outgrowth. PMID: 16164033 |
Ref: Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells. PMID: 16529829 Ref: Recombinant hybrid protein, Shiga toxin and granulocyte macrophage colony stimulating factor effectively induce apoptosis of colon cancer cells. PMID: 16688822 Ref: Osteopontin inhibits macrophage nitric oxide synthesis to enhance tumor proliferation. PMID: 16904962 Ref: Vaccination with melanoma lysate-pulsed dendritic cells, of patients with advanced colorectal carcinoma: report from a phase I study. PMID: 16918131 Ref: Preoperative granulocyte/macrophage colony-stimulating factor (GM-CSF) increases hepatic dendritic cell numbers and clustering with lymphocytes in colorectal cancer patients. PMID: 16920503 Ref: A neoadjuvant/adjuvant randomized trial of colorectal cancer patients vaccinated with an anti-idiotypic antibody, 105AD7, mimicking CD55. PMID: 17121873 Ref: Vascular endothelial growth factor blockade reduces intratumoral regulatory T cells and enhances the efficacy of a GM-CSF-secreting cancer immunotherapy. PMID: 17121902 |
Ref: Pretreatment serum levels of hematopoietic cytokines in patients with colorectal adenomas and cancer. PMID: 16520929 Ref: Successful cancer vaccine therapy for carcinoembryonic antigen (CEA)-expressing colon cancer using genetically modified dendritic cells that express CEA and T helper-type 1 cytokines in CEA transgenic mice. PMID: 17096339 Ref: MUC1-specific immune therapy generates a strong anti-tumor response in a MUC1-tolerant colon cancer model. PMID: 17166639 Ref: Long term administration of granulocyte-macrophage colony stimulating factor decreases development of 1-2 dimethylhydrazine-induced colon cancer in rats. PMID: 17192887 Ref: Long-term immunity elicited by antibody-cytokine fusion proteins protects against sequential challenge with murine mammary and colon malignancies. PMID: 17310381 Ref: Use of an oncolytic virus secreting GM-CSF as combined oncolytic and immunotherapy for treatment of colorectal and hepatic adenocarcinomas. PMID: 17383529 Ref: Perioperative sargramostim (recombinant human GM-CSF) induces an increase in the level of soluble VEGFR1 in colon cancer patients undergoing minimally invasive surgery. PMID: 17512160 Ref: In situ tumor vaccination with adenovirus vectors encoding measles virus fusogenic membrane proteins and cytokines. PMID: 17589921 Ref: Oncolytic virotherapy with an HSV amplicon vector expressing granulocyte-macrophage colony-stimulating factor using the replication-competent HSV type 1 mutant HF10 as a helper virus. PMID: 17693992 Ref: Therapeutic immune response induced by intratumoral expression of the fusogenic membrane protein of vesicular stomatitis virus and cytokines encoded by adenoviral vectors. PMID: 17912460 |
Ref: Influence of varying doses of granulocyte-macrophage colony-stimulating factor on pharmacokinetics and antibody-dependent cellular cytotoxicity. PMID: 17676322 Ref: Combining gene and immunotherapy for prostate cancer. PMID: 17726452 Ref: Phase I clinical trial of autologous ascites-derived exosomes combined with GM-CSF for colorectal cancer. PMID: 18362931 Ref: Induction of apoptosis on K562 cell line and double strand breaks on colon cancer cell line expressing high affinity receptor for granulocyte macrophage-colony stimulating factor (GM-CSF). PMID: 18392089 Ref: Occurrence of autoimmunity in a long-term survivor with metastatic colon carcinoma treated with a new chemo-immunotherapy regimen. PMID: 18467257 Ref: Mucin-induced apoptosis of monocyte-derived dendritic cells during maturation. PMID: 18690650 Ref: Cytokine adjuvanation of therapeutic anti-tumor immunity targeted to cancer mucosa antigens. PMID: 19956776 |
Ref: Perioperative GMCSF limits the proangiogenic plasma protein changes associated with colorectal cancer resection. PMID: 18782657 Ref: Inflammation-associated serum and colon markers as indicators of dietary attenuation of colon carcinogenesis in ob/ob mice. PMID: 19139019 Ref: Anti-programmed death-1 synergizes with granulocyte macrophage colony-stimulating factor--secreting tumor cell immunotherapy providing therapeutic benefit to mice with established tumors. PMID: 19208793 Ref: Suppression of dendritic cells by HMGB1 is associated with lymph node metastasis of human colon cancer. PMID: 19571604 Ref: Role of lipoxins and resolvins as anti-inflammatory and proresolving mediators in colon cancer. PMID: 19601807 Ref: Changes in cytokine and biomarker blood levels in patients with colorectal cancer during dendritic cell-based vaccination. PMID: 19863224 Ref: Serum granulocyte macrophage-colony stimulating factor: a tumor marker in colorectal carcinoma? PMID: 20192576 |
Ref: Tumor cell lysate-pulsed dendritic cells induce a T cell response against colon cancer in vitro and in vivo. PMID: 19669608 Ref: Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. PMID: 20179677 Ref: Regulatory (FoxP3+) T-cell tumor infiltration is a favorable prognostic factor in advanced colon cancer patients undergoing chemo or chemoimmunotherapy. PMID: 20386463 Ref: Dendritic cell vaccination of patients with metastatic colorectal cancer. PMID: 20816019 Ref: Colony-stimulating factor prescribing patterns in patients receiving chemotherapy for cancer. PMID: 20873955 Ref: Macrophages may promote cancer growth via a GM-CSF/HB-EGF paracrine loop that is enhanced by CXCL12. PMID: 20946648 |
Ref: The perioperative granulocyte/lymphocyte ratio is a clinically relevant marker of surgical stress in patients with colorectal cancer. PMID: 21094053 Ref: A Phase I safety study of plasmid DNA immunization targeting carcinoembryonic antigen in colorectal cancer patients. PMID: 21195077 Ref: Intraoperative epidural analgesia prevents the early proinflammatory response to surgical trauma. Results from a prospective randomized clinical trial of intraoperative epidural versus general analgesia. PMID: 21479690 Ref: Synthesis and efficient hepatocyte targeting of galactosylated chitosan as a gene carrier in vitro and in vivo. PMID: 21656667 Ref: A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells. PMID: 21734236 Ref: Cellular Mechanism of Newly Synthesized Indoledione Derivative-induced Immunological Death of Tumor Cell. PMID: 22346779 |
Ref: Induction of IgM, IgA and IgE antibodies in colorectal cancer patients vaccinated with a recombinant CEA protein. PMID: 22382876 Ref: Colony-stimulating factor use and impact on febrile neutropenia among patients with newly diagnosed breast, colorectal, or non-small cell lung cancer who were receiving chemotherapy. PMID: 22392824 Ref: Novel agents in early phase clinical studies on refractory pancreatic cancer. PMID: 22406592 Ref: Attempts to express the A1-GMCSF immunotoxin in the baculovirus expression vector system. PMID: 22484943 Ref: Plasma cytokines as potential response indicators to dietary freeze-dried black raspberries in colorectal cancer patients. PMID: 22823889 |
Ref: Immune-dependent and independent antitumor activity of GM-CSF aberrantly expressed by mouse and human colorectal tumors. PMID: 23108143 Ref: Increased circulation of galectin-3 in cancer induces secretion of metastasis-promoting cytokines from blood vascular endothelium. PMID: 23401226 Ref: Dual blockade of PD-1 and CTLA-4 combined with tumor vaccine effectively restores T-cell rejection function in tumors. PMID: 23633484 Ref: A randomized phase II study of immunization with dendritic cells modified with poxvectors encoding CEA and MUC1 compared with the same poxvectors plus GM-CSF for resected metastatic colorectal cancer. PMID: 23657083 Ref: Profiles of circulating inflammatory cytokines in colorectal cancer (CRC), high cancer risk conditions, and health are distinct. Possible implications for CRC screening and surveillance. PMID: 23726839 Ref: Circulating midkine in malignant and non-malignant colorectal diseases. PMID: 23899719 Ref: Influence of the oncolytic parvovirus H-1, CTLA-4 antibody tremelimumab and cytostatic drugs on the human immune system in a human in vitro model of colorectal cancer cells. PMID: 23986643 Ref: Differential expression of IL-17, 22 and 23 in the progression of colorectal cancer in patients with K-ras mutation: Ras signal inhibition and crosstalk with GM-CSF and IFN-gamma. PMID: 24040001 |
Ref: Evaluation of Pre-Treatment Serum Levels of IL-7 and GM-CSF in Colorectal Cancer Patients. PMID: 24551818 Ref: Interleukin-17A modulates circulating tumor cells in tumor draining vein of colorectal cancers and affects metastases. PMID: 24677375 Ref: Autologous tumor lysate-pulsed dendritic cell immunotherapy with cytokine-induced killer cells improves survival in gastric and colorectal cancer patients. PMID: 24699863 Ref: Induction of dendritic cell maturation in the skin microenvironment by soluble factors derived from colon carcinoma. PMID: 24732313 Ref: GM-CSF Production by Tumor Cells Is Associated with Improved Survival in Colorectal Cancer. PMID: 24737547 Ref: GM-CSF facilitates the development of inflammation-associated colorectal carcinoma. PMID: 24778929 Ref: gammadeltaT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer. PMID: 24816404 Ref: TLR7 ligand augments GM-CSF-initiated antitumor immunity through activation of plasmacytoid dendritic cells. PMID: 24830413 Ref: A safety and feasibility study of an allogeneic colon cancer cell vaccine administered with a granulocyte-macrophage colony stimulating factor-producing bystander cell line in patients with metastatic colorectal cancer. PMID: 24943235 Ref: Association of serum and intratumoral cytokine profiles with tumor stage and neutrophil lymphocyte ratio in colorectal cancer. PMID: 24982357 Ref: Therapy of peritoneally disseminated colon cancer by TAP-deficient embryonic stem cell-derived macrophages in allogeneic recipients. PMID: 25031460 |
Ref: Development of thyroglobulin antibodies after GVAX immunotherapy is associated with prolonged survival. PMID: 24832153 Ref: Selective colorectal cancer cell lysates enhance the immune function of mature dendritic cells in vitro. PMID: 25394863 Ref: Ex vivo generation of myeloid-derived suppressor cells that model the tumor immunosuppressive environment in colorectal cancer. PMID: 25869209 Ref: Laparoscopic surgery for colorectal cancer is not associated with an increase in the circulating levels of several inflammation-related factors. PMID: 25875151 Ref: Lack of significant association between serum inflammatory cytokine profiles and the presence of colorectal adenoma. PMID: 25884547 Ref: Oncolytic tanapoxvirus expressing FliC causes regression of human colorectal cancer xenografts in nude mice. PMID: 25887490 Ref: Targeting CD133high Colorectal Cancer Cells In Vitro and In Vivo With an Asymmetric Bispecific Antibody. PMID: 26049545 Ref: The MUTYH base excision repair gene protects against inflammation-associated colorectal carcinogenesis. PMID: 26109431 Ref: Identification of Novel Biomarkers for Metastatic Colorectal Cancer Using Angiogenesis-Antibody Array and Intracellular Signaling Array. PMID: 26258407 Ref: The influence of ALA-mediated photodynamic therapy on secretion of selected growth factors by colon cancer cells in hypoxia-like environment in vitro. PMID: 26553325 Ref: The emerging therapeutic potential of the oncolytic immunotherapeutic Pexa-Vec (JX-594). PMID: 27512667 |
Ref: Peritumoral adipose tissue as a source of inflammatory and angiogenic factors in colorectal cancer. PMID: 26493186 Ref: Pregnancy-specific glycoprotein 9 (PSG9), a driver for colorectal cancer, enhances angiogenesis via activation of SMAD4. PMID: 27528036 Ref: An effective cytokine adjuvant vaccine induces autologous T-cell response against colon cancer in an animal model. PMID: 27669687 Ref: A novel cancer vaccine with the ability to simultaneously produce anti-PD-1 antibody and GM-CSF in cancer cells and enhance Th1-biased antitumor immunity. PMID: 29263903 |
Ref: Effects of tumor vaccine expressing Granulocyte-Macrophage Colony Stimulating Factor and interleukin-18 fusion on cancer cells and its possible application for cancer immunotherapy. PMID: 26868088 Ref: Frontline Science: Coincidental null mutation of Csf2ralpha in a colony of PI3Kgamma-/- mice causes alveolar macrophage deficiency and fatal respiratory viral infection. PMID: 27468760 Ref: Tumor-infiltrating CD39(+)gammadeltaTregs are novel immunosuppressive T cells in human colorectal cancer. PMID: 28344891 Ref: An Oncolytic Adenovirus Encoding Decorin and Granulocyte Macrophage Colony Stimulating Factor Inhibits Tumor Growth in a Colorectal Tumor Model by Targeting Pro-Tumorigenic Signals and via Immune Activation. PMID: 28530155 Ref: MDSCs are involved in the protumorigenic potentials of GM-CSF in colitis-associated cancer. PMID: 28534709 Ref: Estradiol Has Differential Effects on Acute Colonic Inflammation in the Presence and Absence of Estrogen Receptor beta Expression. PMID: 28573506 Ref: An epithelial-to-mesenchymal transition-inducing potential of granulocyte macrophage colony-stimulating factor in colon cancer. PMID: 28811578 Ref: [5-FU-Injured Bone Marrow Stromal Cells Initiate Stress-induced Premature Senescence of Hematopoietic Cells]. PMID: 28823289 Ref: Suppression of inflammation and tissue damage by a hookworm recombinant protein in experimental colitis. PMID: 29114386 Ref: Assessment of perioperative stress in colorectal cancer by use of in vitro cell models: a systematic review. PMID: 29158975 |
Ref: MUC1- and Survivin-based DNA Vaccine Combining Immunoadjuvants CpG and interleukin-2 in a Bicistronic Expression Plasmid Generates Specific Immune Responses and Antitumour Effects in a Murine Colorectal Carcinoma Model. PMID: 29193199 Ref: PKCalpha in colon cancer cells promotes M1 macrophage polarization via MKK3/6-P38 MAPK pathway. PMID: 29637628 Ref: M10, a novel derivative of Myricetin, prevents ulcerative colitis and colorectal tumor through attenuating robust endoplasmic reticulum stress. PMID: 29757351 Ref: Tumour YAP1 and PTEN expression correlates with tumour-associated myeloid suppressor cell expansion and reduced survival in colorectal cancer. PMID: 29770434 Ref: Subsite heterogeneity in the profiles of circulating cytokines in colorectal cancer. PMID: 29801973 Ref: Cancer-Stimulated CAFs Enhance Monocyte Differentiation and Protumoral TAM Activation via IL6 and GM-CSF Secretion. PMID: 29959142 Ref: Functional Inhibitory Siglec-6 Is Upregulated in Human Colorectal Cancer-Associated Mast Cells. PMID: 30294327 |