Primary Site >> Stomach Cancer

Gene >> CLDN4

Journal: Int J Mol Med. 2003 Jun;11(6):683-9.
Title: CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 12736707
Journal: Oncol Rep. 2005 Feb;13(2):193-9.
Title: Loss of the tight junction protein claudin 4 correlates with histological growth-pattern and differentiation in advanced gastric adenocarcinoma.
Author: Lee, Sang Kil|Moon, Jung|Park, Seung Woo|Song, Si Young|Chung, Jae Bock|Kang, Jin Kyung
PMID: 15643498
Journal: Cancer Res. 2005 Mar 1;65(5):1868-76.
Title: Induction of claudin-4 by nonsteroidal anti-inflammatory drugs and its contribution to their chemopreventive effect.
Author: Mima, Shinji|Tsutsumi, Shinji|Ushijima, Hironori|Takeda, Miho|Fukuda, Ikue|Yokomizo, Kazumi|Suzuki, Keitarou|Sano, Kuniaki|Nakanishi, Tohru|Tomisato, Wataru|Tsuchiya, Tomofusa|Mizushima, Tohru
PMID: 15753385
Journal: Hum Pathol. 2005 Aug;36(8):886-92.
Title: Claudin expression in gastric adenocarcinomas: a tissue microarray study with prognostic correlation.
Author: Resnick, Murray B|Gavilanez, Mariuxi|Newton, Eric|Konkin, Tamako|Bhattacharya, Baishali|Britt, Deborah E|Sabo, Edmond|Moss, Steven F
PMID: 16112005
Journal: Virchows Arch. 2006 Jan;448(1):52-8.
Title: Claudins 1, 3, 4 and 5 in gastric carcinoma, loss of claudin expression associates with the diffuse subtype.
Author: Soini, Y|Tommola, S|Helin, H|Martikainen, P
PMID: 16220299
Journal: Oncol Rep. 2006 Jan;15(1):57-64.
Title: Identification of differential gene expression between intestinal and diffuse gastric cancer using cDNA microarray.
Author: Wu, Chi-Ming|Lee, Yun-Shien|Wang, Tzu-Hao|Lee, Li-Yu|Kong, Wei-Hsiang|Chen, En-Shih|Wei, Min-Li|Liang, Ying|Hwang, Tsann-Long
PMID: 16328034
Journal: Cancer Epidemiol Biomarkers Prev. 2006 Feb;15(2):281-7.
Title: Claudin-4, mitogen-activated protein kinase kinase 4, and stratifin are markers of gastric adenocarcinoma precursor lesions.
Author: Cunningham, Steven C|Kamangar, Farin|Kim, Min P|Hammoud, Sommer|Haque, Raqeeb|Iacobuzio-Donahue, Christine A|Maitra, Anirban|Ashfaq, Raheela|Hustinx, Steven|Heitmiller, Richard E|Choti, Michael A|Lillemoe, Keith D|Cameron, John L|Yeo, Charles J|Schulick,
PMID: 16492916
Journal: BMC Cancer. 2006 Jul 12;6:186.
Title: The claudin gene family: expression in normal and neoplastic tissues.
Author: Hewitt, Kyle J|Agarwal, Rachana|Morin, Patrice J
PMID: 16836752
Journal: Oncol Rep. 2006 Oct;16(4):729-34.
Title: Differential expression of claudin-4 between intestinal and diffuse-type gastric cancer.
Author: Kuo, Wen-Ling|Lee, Li-Yu|Wu, Chi-Ming|Wang, Chee-Chan|Yu, Jau-Song|Liang, Ying|Lo, Chih-Hong|Huang, Kuo-Hao|Hwang, Tsann-Long
PMID: 16969486
Journal: Cancer Sci. 2007 Jul;98(7):1014-9. Epub 2007 Apr 24.
Title: Gastric and intestinal claudin expression at the invasive front of gastric carcinoma.
Author: Matsuda, Yoshiko|Semba, Shuho|Ueda, Junya|Fuku, Takeichi|Hasuo, Tadateru|Chiba, Hideki|Sawada, Norimasa|Kuroda, Yoshikazu|Yokozaki, Hiroshi
PMID: 17459057
Journal: Pathol Int. 2007 Oct;57(10):635-44.
Title: Pathophysiological role of the activation of p38 mitogen-activated protein kinases in poorly differentiated gastric cancer.
Author: Atsumi, Tomoaki|Kato, Katsuaki|Uno, Kaname|Iijima, Katsunori|Koike, Tomoyuki|Imatani, Akira|Ohara, Syuichi|Shimosegawa, Tooru
PMID: 17803652
Journal: Pathol Int. 2008 Mar;58(3):156-63.
Title: Cdx2 transcription factor regulates claudin-3 and claudin-4 expression during intestinal differentiation of gastric carcinoma.
Author: Satake, Shinya|Semba, Shuho|Matsuda, Yoshiko|Usami, Yu|Chiba, Hideki|Sawada, Norimasa|Kasuga, Masato|Yokozaki, Hiroshi
PMID: 18251778
Journal: Histol Histopathol. 2008 May;23(5):515-21.
Title: Expression of matrix metalloproteinases MMP-2 and MMP-9 in gastric cancer and their relation to claudin-4 expression.
Author: Lee, Li-Yu|Wu, Chi-Ming|Wang, Chee-Chan|Yu, Jau-Song|Liang, Ying|Huang, Kuo-Hao|Lo, Chih-Hong|Hwang, Tsann-Long
PMID: 18283635
Journal: Pathol Int. 2008 Jun;58(6):371-7.
Title: Prognostic significance of intestinal claudins in high-risk synchronous and metachronous multiple gastric epithelial neoplasias after initial endoscopic submucosal dissection.
Author: Semba, Shuho|Hasuo, Tadateru|Satake, Shinya|Nakayama, Fumihito|Yokozaki, Hiroshi
PMID: 18477216
Journal: Gastric Cancer. 2009;12(1):43-51.
Title: Expression of tight-junction-associated proteins in human gastric cancer: downregulation of claudin-4 correlates with tumor aggressiveness and survival.
Author: Ohtani, Satoshi|Terashima, Masanori|Satoh, Jun|Soeta, Nobutoshi|Saze, Zenichiroh|Kashimura, Seigo|Ohsuka, Fumihiko|Hoshino, Yutaka|Kogure, Michihiko|Gotoh, Mitsukazu
PMID: 19390931
Journal: Int J Oncol. 2009 Jun;34(6):1737-42.
Title: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB.
Author: Katoh, Masuko|Katoh, Masaru
PMID: 19424592
Journal: Cancer Lett. 2009 Feb 8;274(1):143-50.
Title: Phosphatase activity of nuclear PTEN is required for CDX2-mediated intestinal differentiation of gastric carcinoma.
Author: Semba, Shuho|Satake, Shinya|Matsushita, Mai|Yokozaki, Hiroshi
PMID: 18996641
Journal: J Gastroenterol Hepatol. 2009 Sep;24(9):1527-33.
Title: Significance of lymphatic invasion and cancer invasion-related proteins on lymph node metastasis in gastric cancer.
Author: Kamata, Itaru|Ishikawa, Yukio|Akishima-Fukasawa, Yuri|Ito, Kinji|Akasaka, Yoshikiyo|Uzuki, Miwa|Fujimoto, Ai|Morita, Hiroshi|Tamai, Seiichi|Maehara, Tadaaki|Ogata, Kentaro|Shimokawa, Reiko|Igarashi, Yoshinori|Miki, Kazumasa|Ishii, Toshiharu
PMID: 19383080
Journal: Exp Ther Med. 2010 Sep;1(5):789-797.
Title: Claudin-4 expression is associated with tumor invasion, MMP-2 and MMP-9 expression in gastric cancer.
Author: Hwang, Tsann-Long|Lee, Li-Yu|Wang, Chee-Chan|Liang, Ying|Huang, Shu-Fang|Wu, Chi-Ming
PMID: 22993603
Journal: Lab Invest. 2011 Nov;91(11):1652-67.
Title: Claudin-4 overexpression is associated with epigenetic derepression in gastric carcinoma.
Author: Kwon, Mi Jeong|Kim, Seok-Hyung|Jeong, Hae Min|Jung, Hun Soon|Kim, Sung-Su|Lee, Jae Eun|Gye, Myung Chan|Erkin, Ozgur Cem|Koh, Sang Seok|Choi, Yoon-La|Park, Cheol Keun|Shin, Young Kee
PMID: 21844869
Journal: Dig Dis Sci. 2012 Jun;57(6):1562-7.
Title: Down-regulation of claudin-3 is associated with proliferative potential in early gastric cancers.
Author: Okugawa, Takuya|Oshima, Tadayuki|Chen, Xin|Hori, Kazutoshi|Tomita, Toshihiko|Fukui, Hirokazu|Watari, Jiro|Matsumoto, Takayuki|Miwa, Hiroto
PMID: 22290341
Journal: World J Surg Oncol. 2013 Jul 4;11:150.
Title: Clinicopathological significance of claudin-4 in gastric carcinoma.
Author: Zhu, Jin-Liang|Gao, Peng|Wang, Zhen-Ning|Song, Yong-Xi|Li, Ai-Lin|Xu, Ying-Ying|Wang, Mei-Xian|Xu, Hui-Mian
PMID: 23822740
Journal: Oncol Lett. 2014 Sep;8(3):1367-1371.
Title: Claudin-4 expression in gastric cancer cells enhances the invasion and is associated with the increased level of matrix metalloproteinase-2 and -9 expression.
Author: Hwang, Tsann-Long|Changchien, Tzu-Tsung|Wang, Chee-Chan|Wu, Chi-Ming
PMID: 25120725
Journal: Int J Clin Exp Pathol. 2015 Jan 1;8(1):881-7. eCollection 2015.
Title: The expression patterns of tight junction protein claudin-1, -3, and -4 in human gastric neoplasms and adjacent non-neoplastic tissues.
Author: Wang, Haiming|Yang, Xingwang
PMID: 25755790
Journal: Arab J Gastroenterol. 2015 Sep-Dec;16(3-4):105-12.
Title: Tight junction protein claudin 4 in gastric carcinoma and its relation to lymphangiogenic activity.
Author: Shareef, Mohamed Moustafa|Radi, Dina Mohammed Adel|Eid, Asmaa Mustafa Mohammed
PMID: 26526513
Journal: Oncol Rep. 2015 Oct;34(4):2047-53.
Title: Clinicopathological significance of N-cadherin and VEGF in advanced gastric cancer brain metastasis and the effects of metformin in preclinical models.
Author: Jun, Kyong-Hwa|Lee, Jung Eun|Kim, Se Hoon|Jung, Ji-Han|Choi, Hyun-Joo|Kim, Young Il|Chin, Hyung-Min|Yang, Seung-Ho
PMID: 26260219
Journal: World J Surg Oncol. 2015 Jun 25;13:207.
Title: Prognostic and clinical significance of claudin-4 in gastric cancer: a meta-analysis.
Author: Liu, Jin-Xin|Wei, Zhao-Yi|Chen, Jian-She|Lu, Hai-Chao|Hao, Liang|Li, Wen-Jing
PMID: 26109060
Journal: Biochem Biophys Res Commun. 2015 Apr 10;459(3):379-86.
Title: Interleukin-18 enhances breast cancer cell migration via down-regulation of claudin-12 and induction of the p38 MAPK pathway.
Author: Yang, Yoolhee|Cheon, Soyoung|Jung, Min Kyung|Song, Seok Bean|Kim, Daejin|Kim, Hee Jung|Park, Hyunjeong|Bang, Sa Ik|Cho, Daeho
PMID: 25727011
Journal: Onco Targets Ther. 2016 May 27;9:3205-12.
Title: Clinicopathological significance of claudin 4 expression in gastric carcinoma: a systematic review and meta-analysis.
Author: Chen, Xiaowan|Zhao, Junhua|Li, Ailin|Gao, Peng|Sun, Jingxu|Song, Yongxi|Liu, Jingjing|Chen, Ping|Wang, Zhenning
PMID: 27313466
Journal: Pharmacol Res Perspect. 2016 Sep 27;4(5):e00266.
Title: Efficacy and safety evaluation of claudin-4-targeted antitumor therapy using a human and mouse cross-reactive monoclonal antibody.
Author: Hashimoto, Yosuke|Kawahigashi, Yumi|Hata, Tomoyuki|Li, Xiangru|Watari, Akihiro|Tada, Minoru|Ishii-Watabe, Akiko|Okada, Yoshiaki|Doi, Takefumi|Fukasawa, Masayoshi|Kuniyasu, Hiroki|Yagi, Kiyohito|Kondoh, Masuo
PMID: 27713828
Journal: Oncol Lett. 2016 Nov;12(5):3866-3874.
Title: Comparative analysis of gene expression profiles of gastric cardia adenocarcinoma and gastric non-cardia adenocarcinoma.
Author: Song, Bin|Du, Juan|Deng, Neng|Ren, Ji-Chen|Shu, Zhen-Bo
PMID: 27895742
Journal: J BUON. 2017 Mar-Apr;22(2):403-409.
Title: The expression of Claudin-4 in gastric cancer tissue: A single center experience.
Author: Moris, Demetrios|Schizas, Dimitrios|Michalinos, Adamantios|Kanavidis, Prodromos|Dimitrokallis, Nikolaos|Alexandrou, Andreas|Misiakos, Evangelos|Liakakos, Theodoros
PMID: 28534362
Journal: Nat Commun. 2017 Aug 18;8(1):289.
Title: Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion.
Author: Song, Yong-Xi|Sun, Jing-Xu|Zhao, Jun-Hua|Yang, Yu-Chong|Shi, Jin-Xin|Wu, Zhong-Hua|Chen, Xiao-Wan|Gao, Peng|Miao, Zhi-Feng|Wang, Zhen-Ning
PMID: 28819095