Primary Site >> Stomach Cancer
Gene >> CLDN4
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Ref: CLDN23 gene, frequently down-regulated in intestinal-type gastric cancer, is a novel member of CLAUDIN gene family. PMID: 12736707 |
Ref: Loss of the tight junction protein claudin 4 correlates with histological growth-pattern and differentiation in advanced gastric adenocarcinoma. PMID: 15643498 Ref: Induction of claudin-4 by nonsteroidal anti-inflammatory drugs and its contribution to their chemopreventive effect. PMID: 15753385 Ref: Claudin expression in gastric adenocarcinomas: a tissue microarray study with prognostic correlation. PMID: 16112005 |
Ref: Claudins 1, 3, 4 and 5 in gastric carcinoma, loss of claudin expression associates with the diffuse subtype. PMID: 16220299 Ref: Identification of differential gene expression between intestinal and diffuse gastric cancer using cDNA microarray. PMID: 16328034 Ref: Claudin-4, mitogen-activated protein kinase kinase 4, and stratifin are markers of gastric adenocarcinoma precursor lesions. PMID: 16492916 Ref: The claudin gene family: expression in normal and neoplastic tissues. PMID: 16836752 Ref: Differential expression of claudin-4 between intestinal and diffuse-type gastric cancer. PMID: 16969486 |
Ref: Gastric and intestinal claudin expression at the invasive front of gastric carcinoma. PMID: 17459057 Ref: Pathophysiological role of the activation of p38 mitogen-activated protein kinases in poorly differentiated gastric cancer. PMID: 17803652 |
Ref: Cdx2 transcription factor regulates claudin-3 and claudin-4 expression during intestinal differentiation of gastric carcinoma. PMID: 18251778 Ref: Expression of matrix metalloproteinases MMP-2 and MMP-9 in gastric cancer and their relation to claudin-4 expression. PMID: 18283635 Ref: Prognostic significance of intestinal claudins in high-risk synchronous and metachronous multiple gastric epithelial neoplasias after initial endoscopic submucosal dissection. PMID: 18477216 |
Ref: Phosphatase activity of nuclear PTEN is required for CDX2-mediated intestinal differentiation of gastric carcinoma. PMID: 18996641 Ref: Significance of lymphatic invasion and cancer invasion-related proteins on lymph node metastasis in gastric cancer. PMID: 19383080 Ref: Expression of tight-junction-associated proteins in human gastric cancer: downregulation of claudin-4 correlates with tumor aggressiveness and survival. PMID: 19390931 Ref: Integrative genomic analyses of ZEB2: Transcriptional regulation of ZEB2 based on SMADs, ETS1, HIF1alpha, POU/OCT, and NF-kappaB. PMID: 19424592 |
Ref: Claudin-4 expression is associated with tumor invasion, MMP-2 and MMP-9 expression in gastric cancer. PMID: 22993603 |
Ref: Claudin-4 overexpression is associated with epigenetic derepression in gastric carcinoma. PMID: 21844869 |
Ref: Down-regulation of claudin-3 is associated with proliferative potential in early gastric cancers. PMID: 22290341 |
Ref: Clinicopathological significance of claudin-4 in gastric carcinoma. PMID: 23822740 |
Ref: Claudin-4 expression in gastric cancer cells enhances the invasion and is associated with the increased level of matrix metalloproteinase-2 and -9 expression. PMID: 25120725 |
Ref: Interleukin-18 enhances breast cancer cell migration via down-regulation of claudin-12 and induction of the p38 MAPK pathway. PMID: 25727011 Ref: The expression patterns of tight junction protein claudin-1, -3, and -4 in human gastric neoplasms and adjacent non-neoplastic tissues. PMID: 25755790 Ref: Prognostic and clinical significance of claudin-4 in gastric cancer: a meta-analysis. PMID: 26109060 Ref: Clinicopathological significance of N-cadherin and VEGF in advanced gastric cancer brain metastasis and the effects of metformin in preclinical models. PMID: 26260219 Ref: Tight junction protein claudin 4 in gastric carcinoma and its relation to lymphangiogenic activity. PMID: 26526513 |
Ref: Clinicopathological significance of claudin 4 expression in gastric carcinoma: a systematic review and meta-analysis. PMID: 27313466 Ref: Efficacy and safety evaluation of claudin-4-targeted antitumor therapy using a human and mouse cross-reactive monoclonal antibody. PMID: 27713828 Ref: Comparative analysis of gene expression profiles of gastric cardia adenocarcinoma and gastric non-cardia adenocarcinoma. PMID: 27895742 |
Ref: The expression of Claudin-4 in gastric cancer tissue: A single center experience. PMID: 28534362 Ref: Non-coding RNAs participate in the regulatory network of CLDN4 via ceRNA mediated miRNA evasion. PMID: 28819095 |