Primary Site >> Colorectal Cancer
Gene >> CHFR
| 1. | |||||||||||
| Journal: | Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7818-23. Epub 2003 Jun 16. | ||||||||||
| Title: | Epigenetic inactivation of CHFR in human tumors. | ||||||||||
| Author: | Toyota, Minoru|Sasaki, Yasushi|Satoh, Ayumi|Ogi, Kazuhiro|Kikuchi, Takefumi|Suzuki, Hiromu|Mita, Hiroaki|Tanaka, Nobuyuki|Itoh, Fumio|Issa, Jean-Pierre J|Jair, Kam-Wing|Schuebel, Kornel E|Imai, Kohzoh|Tokino, Takashi | ||||||||||
| PMID: | 12810945 | ||||||||||
| 2. | |||||||||||
| Journal: | Oncogene. 2003 Dec 4;22(55):8956-60. | ||||||||||
| Title: | Chfr inactivation is not associated to chromosomal instability in colon cancers. | ||||||||||
| Author: | Bertholon, Jacques|Wang, Qing|Falette, Nicole|Verny, Carole|Auclair, Jessie|Chassot, Christelle|Navarro, Claudine|Saurin, Jean-Christophe|Puisieux, Alain | ||||||||||
| PMID: | 14654793 | ||||||||||
| 3. | |||||||||||
| Journal: | Carcinogenesis. 2003 Jan;24(1):47-51. | ||||||||||
| Title: | Frequent hypermethylation of the 5' CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer. | ||||||||||
| Author: | Corn, Paul G|Summers, Matthew K|Fogt, Franz|Virmani, Arvind K|Gazdar, Adi F|Halazonetis, Thanos D|El-Deiry, Wafik S | ||||||||||
| PMID: | 12538348 | ||||||||||
| 4. | |||||||||||
| Journal: | Carcinogenesis. 2005 Jun;26(6):1152-6. Epub 2005 Mar 10. | ||||||||||
| Title: | CHFR promoter hypermethylation in colon cancer correlates with the microsatellite instability phenotype. | ||||||||||
| Author: | Brandes, Johann C|van Engeland, Manon|Wouters, Kim A D|Weijenberg, Matty P|Herman, James G | ||||||||||
| PMID: | 15760919 | ||||||||||
| 5. | |||||||||||
| Journal: | Breast Cancer Res Treat. 2006 May;97(2):199-203. Epub 2006 Feb 24. | ||||||||||
| Title: | Aberrant hypermethylation of the promoter region of the CHFR gene is rare in primary breast cancer. | ||||||||||
| Author: | Tokunaga, Eriko|Oki, Eiji|Nishida, Kojiro|Koga, Tadashi|Yoshida, Rintaro|Ikeda, Keisuke|Kojima, Aya|Egashira, Akinori|Morita, Masaru|Kakeji, Yoshihiro|Maehara, Yoshihiko | ||||||||||
| PMID: | 16502017 | ||||||||||
| 6. | |||||||||||
| Journal: | Cell Oncol. 2006;28(5-6):247-57. | ||||||||||
| Title: | Promoter methylation precedes chromosomal alterations in colorectal cancer development. | ||||||||||
| Author: | Derks, Sarah|Postma, Cindy|Moerkerk, Peter T M|van den Bosch, Sandra M|Carvalho, Beatriz|Hermsen, Mario A J A|Giaretti, Walter|Herman, James G|Weijenberg, Matty P|de Bruine, Adriaan P|Meijer, Gerrit A|van Engeland, Manon | ||||||||||
| PMID: | 17167178 | ||||||||||
| 7. | |||||||||||
| Journal: | Anticancer Res. 2006 Nov-Dec;26(6B):4267-70. | ||||||||||
| Title: | Aberrant methylation of the CHFR gene is frequently detected in non-invasive colorectal cancer. | ||||||||||
| Author: | Morioka, Yuki|Hibi, Kenji|Sakai, Mitsuru|Koike, Masahiko|Fujiwara, Michitaka|Kodera, Yasuhiro|Ito, Katsuki|Nakao, Akimasa | ||||||||||
| PMID: | 17201143 | ||||||||||
| 8. | |||||||||||
| Journal: | Carcinogenesis. 2008 Feb;29(2):434-9. | ||||||||||
| Title: | Integrated analysis of chromosomal, microsatellite and epigenetic instability in colorectal cancer identifies specific associations between promoter methylation of pivotal tumour suppressor and DNA repair genes and specific chromosomal alterations. | ||||||||||
| Author: | Derks, Sarah|Postma, Cindy|Carvalho, Beatriz|van den Bosch, Sandra M|Moerkerk, Peter T M|Herman, James G|Weijenberg, Matty P|de Bruine, Adriaan P|Meijer, Gerrit A|van Engeland, Manon | ||||||||||
| PMID: | 18048385 | ||||||||||
| 9. | |||||||||||
| Journal: | Cancer Lett. 2008 Feb 18;260(1-2):170-9. | ||||||||||
| Title: | Coding region polymorphisms in the CHFR mitotic stress checkpoint gene are associated with colorectal cancer risk. | ||||||||||
| Author: | Kang, Hio Chung|Kim, Il-Jin|Jang, Sang-Geun|Hong, Seung-Hyun|Hwang, Jung-Ah|Shin, Hai-Rim|Park, Jae-Gahb | ||||||||||
| PMID: | 18079053 | ||||||||||
| 10. | |||||||||||
| Journal: | Mod Pathol. 2008 Mar;21(3):245-55. | ||||||||||
| Title: | CpG island methylator phenotype-low (CIMP-low) colorectal cancer shows not only few methylated CIMP-high-specific CpG islands, but also low-level methylation at individual loci. | ||||||||||
| Author: | Kawasaki, Takako|Ohnishi, Mutsuko|Nosho, Katsuhiko|Suemoto, Yuko|Kirkner, Gregory J|Meyerhardt, Jeffrey A|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 18204436 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Res. 2008 Jun 15;68(12):4597-605. | ||||||||||
| Title: | Epigenetic signatures of familial cancer are characteristic of tumor type and family category. | ||||||||||
| Author: | Joensuu, Emmi I|Abdel-Rahman, Wael M|Ollikainen, Miina|Ruosaari, Salla|Knuutila, Sakari|Peltomaki, Paivi | ||||||||||
| PMID: | 18559504 | ||||||||||
| 12. | |||||||||||
| Journal: | PLoS One. 2008;3(11):e3698. | ||||||||||
| Title: | Comprehensive biostatistical analysis of CpG island methylator phenotype in colorectal cancer using a large population-based sample. | ||||||||||
| Author: | Nosho, Katsuhiko|Irahara, Natsumi|Shima, Kaori|Kure, Shoko|Kirkner, Gregory J|Schernhammer, Eva S|Hazra, Aditi|Hunter, David J|Quackenbush, John|Spiegelman, Donna|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 19002263 | ||||||||||
| 13. | |||||||||||
| Journal: | Gastroenterology. 2009 Nov;137(5):1609-20.e1-3. | ||||||||||
| Title: | A prospective cohort study shows unique epigenetic, genetic, and prognostic features of synchronous colorectal cancers. | ||||||||||
| Author: | Nosho, Katsuhiko|Kure, Shoko|Irahara, Natsumi|Shima, Kaori|Baba, Yoshifumi|Spiegelman, Donna|Meyerhardt, Jeffrey A|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 19686742 | ||||||||||
| 14. | |||||||||||
| Journal: | J Clin Invest. 2009 Sep;119(9):2714-24. | ||||||||||
| Title: | Deficiencies in Chfr and Mlh1 synergistically enhance tumor susceptibility in mice. | ||||||||||
| Author: | Fu, Zheng|Regan, Kevin|Zhang, Lizhi|Muders, Michael H|Thibodeau, Stephen N|French, Amy|Wu, Yanhong|Kaufmann, Scott H|Lingle, Wilma L|Chen, Junjie|Tindall, Donald J | ||||||||||
| PMID: | 19690386 | ||||||||||
| 15. | |||||||||||
| Journal: | Clin Cancer Res. 2009 Jun 1;15(11):3663-71. | ||||||||||
| Title: | DNMT3B expression might contribute to CpG island methylator phenotype in colorectal cancer. | ||||||||||
| Author: | Nosho, Katsuhiko|Shima, Kaori|Irahara, Natsumi|Kure, Shoko|Baba, Yoshifumi|Kirkner, Gregory J|Chen, Li|Gokhale, Sumita|Hazra, Aditi|Spiegelman, Donna|Giovannucci, Edward L|Jaenisch, Rudolf|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 19470733 | ||||||||||
| 16. | |||||||||||
| Journal: | Neoplasia. 2009 Jan;11(1):87-95. | ||||||||||
| Title: | JC virus T-antigen in colorectal cancer is associated with p53 expression and chromosomal instability, independent of CpG island methylator phenotype. | ||||||||||
| Author: | Nosho, Katsuhiko|Shima, Kaori|Kure, Shoko|Irahara, Natsumi|Baba, Yoshifumi|Chen, Li|Kirkner, Gregory J|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 19107235 | ||||||||||
| 17. | |||||||||||
| Journal: | Gut. 2009 Jan;58(1):90-6. | ||||||||||
| Title: | CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer. | ||||||||||
| Author: | Ogino, Shuji|Nosho, Katsuhiko|Kirkner, Gregory J|Kawasaki, Takako|Meyerhardt, Jeffrey A|Loda, Massimo|Giovannucci, Edward L|Fuchs, Charles S | ||||||||||
| PMID: | 18832519 | ||||||||||
| 18. | |||||||||||
| Journal: | Mod Pathol. 2009 Jul;22(7):922-32. | ||||||||||
| Title: | SIRT1 histone deacetylase expression is associated with microsatellite instability and CpG island methylator phenotype in colorectal cancer. | ||||||||||
| Author: | Nosho, Katsuhiko|Shima, Kaori|Irahara, Natsumi|Kure, Shoko|Firestein, Ron|Baba, Yoshifumi|Toyoda, Saori|Chen, Li|Hazra, Aditi|Giovannucci, Edward L|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 19430421 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncol Rep. 2010 Jan;23(1):191-7. | ||||||||||
| Title: | CpG island methylation of BNIP3 predicts resistance against S-1/CPT-11 combined therapy in colorectal cancer patients. | ||||||||||
| Author: | Hiraki, Masatsugu|Kitajima, Yoshihiko|Nakafusa, Yuji|Nakamura, Jun|Hashiguchi, Kazuyoshi|Sumi, Kenji|Noshiro, Hirokazu|Miyazaki, Kohji | ||||||||||
| PMID: | 19956881 | ||||||||||
| 20. | |||||||||||
| Journal: | Adv Genet. 2010;70:309-23. | ||||||||||
| Title: | Epigenetic drivers of genetic alterations. | ||||||||||
| Author: | Toyota, Minoru|Suzuki, Hiromu | ||||||||||
| PMID: | 20920753 | ||||||||||
| 21. | |||||||||||
| Journal: | Am J Pathol. 2010 Dec;177(6):2731-40. | ||||||||||
| Title: | Novel application of structural equation modeling to correlation structure analysis of CpG island methylation in colorectal cancer. | ||||||||||
| Author: | Tanaka, Noriko|Huttenhower, Curtis|Nosho, Katsuhiko|Baba, Yoshifumi|Shima, Kaori|Quackenbush, John|Haigis, Kevin M|Giovannucci, Edward|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 21037082 | ||||||||||
| 22. | |||||||||||
| Journal: | Anticancer Res. 2010 Dec;30(12):4811-8. | ||||||||||
| Title: | Aberrant methylation of heparan sulfate glucosamine 3-O-sulfotransferase 2 genes as a biomarker in colorectal cancer. | ||||||||||
| Author: | Tokuyama, Yasuharu|Takahashi, Takao|Okumura, Naoki|Nonaka, Kenichi|Kawaguchi, Yoshihiro|Yamaguchi, Kazuya|Osada, Shinji|Gazdar, Adi|Yoshida, Kazuhiro | ||||||||||
| PMID: | 21187457 | ||||||||||
| 23. | |||||||||||
| Journal: | Clin Cancer Res. 2011 Jul 1;17(13):4531-40. | ||||||||||
| Title: | Association of CHFR promoter methylation with disease recurrence in locally advanced colon cancer. | ||||||||||
| Author: | Tanaka, Motofumi|Chang, Ping|Li, Yanan|Li, Donghui|Overman, Michael|Maru, Dipen M|Sethi, Salil|Phillips, Jonathan|Bland, Gail L|Abbruzzese, James L|Eng, Cathy | ||||||||||
| PMID: | 21551253 | ||||||||||
| 24. | |||||||||||
| Journal: | PLoS One. 2011;6(6):e21102. | ||||||||||
| Title: | B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP). | ||||||||||
| Author: | Schernhammer, Eva S|Giovannucci, Edward|Baba, Yoshifumi|Fuchs, Charles S|Ogino, Shuji | ||||||||||
| PMID: | 21738611 | ||||||||||
| 25. | |||||||||||
| Journal: | Br J Surg. 2011 May;98(5):724-34. | ||||||||||
| Title: | Methylation profiling of rectal cancer identifies novel markers of early-stage disease. | ||||||||||
| Author: | Leong, K J|Wei, W|Tannahill, L A|Caldwell, G M|Jones, C E|Morton, D G|Matthews, G M|Bach, S P | ||||||||||
| PMID: | 21360524 | ||||||||||
| 26. | |||||||||||
| Journal: | J Cell Mol Med. 2011 Sep;15(9):1941-54. | ||||||||||
| Title: | Human embryonic stem cells and metastatic colorectal cancer cells shared the common endogenous human microRNA-26b. | ||||||||||
| Author: | Ma, Yan-Lei|Zhang, Peng|Wang, Feng|Moyer, Mary Pat|Yang, Jian-Jun|Liu, Zhi-Hua|Peng, Jia-Yuan|Chen, Hong-Qi|Zhou, Yu-Kun|Liu, Wei-Jie|Qin, Huan-Long | ||||||||||
| PMID: | 20831567 | ||||||||||
| 27. | |||||||||||
| Journal: | Int J Cancer. 2014 Feb 1;134(3):596-605. | ||||||||||
| Title: | CHFR silencing or microsatellite instability is associated with increased antitumor activity of docetaxel or gemcitabine in colorectal cancer. | ||||||||||
| Author: | Pelosof, Lorraine|Yerram, Sashidhar R|Ahuja, Nita|Delmas, Andrew|Danilova, Ludmila|Herman, James G|Azad, Nilofer S | ||||||||||
| PMID: | 23873170 | ||||||||||
| 28. | |||||||||||
| Journal: | Clin Cancer Res. 2014 Jun 15;20(12):3261-71. | ||||||||||
| Title: | CHFR promoter methylation indicates poor prognosis in stage II microsatellite stable colorectal cancer. | ||||||||||
| Author: | Cleven, Arjen H G|Derks, Sarah|Draht, Muriel X G|Smits, Kim M|Melotte, Veerle|Van Neste, Leander|Tournier, Benjamin|Jooste, Valerie|Chapusot, Caroline|Weijenberg, Matty P|Herman, James G|de Bruine, Adriaan P|van Engeland, Manon | ||||||||||
| PMID: | 24928946 | ||||||||||
| 29. | |||||||||||
| Journal: | Br J Surg. 2014 Sep;101(10):1299-309. | ||||||||||
| Title: | Biomarker-based treatment selection in early-stage rectal cancer to promote organ preservation. | ||||||||||
| Author: | Leong, K J|Beggs, A|James, J|Morton, D G|Matthews, G M|Bach, S P | ||||||||||
| PMID: | 25052224 | ||||||||||
| 30. | |||||||||||
| Journal: | Mol Carcinog. 2016 Dec;55(12):2077-2088. | ||||||||||
| Title: | Integrated analysis of DNA methylation and mutations in esophageal squamous cell carcinoma. | ||||||||||
| Author: | Kishino, Takayoshi|Niwa, Tohru|Yamashita, Satoshi|Takahashi, Takamasa|Nakazato, Hidetsugu|Nakajima, Takeshi|Igaki, Hiroyasu|Tachimori, Yuji|Suzuki, Yasuyuki|Ushijima, Toshikazu | ||||||||||
| PMID: | 26756304 | ||||||||||
| 31. | |||||||||||
| Journal: | Life Sci. 2016 Dec 15;167:67-77. | ||||||||||
| Title: | Arsenic trioxide induces cell cycle arrest and alters DNA methylation patterns of cell cycle regulatory genes in colorectal cancer cells. | ||||||||||
| Author: | Eyvani, Haniyeh|Moghaddaskho, Farima|Kabuli, Majid|Zekri, Ali|Momeny, Majid|Tavakkoly-Bazzaz, Javad|Alimoghaddam, Kamran|Ghavamzadeh, Ardeshir|Ghaffari, Seyed H | ||||||||||
| PMID: | 27769816 | ||||||||||
| 32. | |||||||||||
| Journal: | Oncotarget. 2017 Jul 20;8(51):89142-89148. | ||||||||||
| Title: | The diagnostic and prognostic value of CHFR hypermethylation in colorectal cancer, a meta-analysis and literature review. | ||||||||||
| Author: | Sun, Zhulei|Liu, Juncai|Jing, Hong|Dong, Shu-Xiao|Wu, Jiang | ||||||||||
| PMID: | 29179506 | ||||||||||
| 33. | |||||||||||
| Journal: | Ann Oncol. 2018 Jan 1;29(1):139-144. | ||||||||||
| Title: | Phase II study of nab-paclitaxel in refractory small bowel adenocarcinoma and CpG island methylator phenotype (CIMP)-high colorectal cancer. | ||||||||||
| Author: | Overman, M J|Adam, L|Raghav, K|Wang, J|Kee, B|Fogelman, D|Eng, C|Vilar, E|Shroff, R|Dasari, A|Wolff, R|Morris, J|Karunasena, E|Pisanic, R 2nd|Azad, N|Kopetz, S | ||||||||||
| PMID: | 29069279 | ||||||||||