Primary Site >> Pancreatic Cancer
Gene >> CHEK2
| 1. | |||||||||||
| Journal: | Breast Cancer Res. 2004;6(4):R366-71. Epub 2004 May 14. | ||||||||||
| Title: | No germline mutations in the histone acetyltransferase gene EP300 in BRCA1 and BRCA2 negative families with breast cancer and gastric, pancreatic, or colorectal cancer. | ||||||||||
| Author: | Campbell, Ian G|Choong, David|Chenevix-Trench, Georgia | ||||||||||
| PMID: | 15217503 | ||||||||||
| 2. | |||||||||||
| Journal: | Anticancer Drugs. 2004 Aug;15(7):689-96. | ||||||||||
| Title: | Cellular response and molecular mechanism of antitumor activity by leinamycin in MiaPaCa human pancreatic cancer cells. | ||||||||||
| Author: | Bassett, Stephen|Urrabaz, Rheanna|Sun, Daekyu | ||||||||||
| PMID: | 15269600 | ||||||||||
| 3. | |||||||||||
| Journal: | Cytogenet Genome Res. 2004;104(1-4):333-40. | ||||||||||
| Title: | Possible causes of chromosome instability: comparison of chromosomal abnormalities in cancer cell lines with mutations in BRCA1, BRCA2, CHK2 and BUB1. | ||||||||||
| Author: | Grigorova, M|Staines, J M|Ozdag, H|Caldas, C|Edwards, P A W | ||||||||||
| PMID: | 15162061 | ||||||||||
| 4. | |||||||||||
| Journal: | Fam Cancer. 2006;5(4):305-8. Epub 2006 Jul 20. | ||||||||||
| Title: | Low frequency of CHEK2 mutations in familial pancreatic cancer. | ||||||||||
| Author: | Bartsch, Detlef K|Krysewski, Kristina|Sina-Frey, Mercedes|Fendrich, Volker|Rieder, Harald|Langer, Peter|Kress, Ralf|Schneider, Margarete|Hahn, Stephan A|Slater, Emily P | ||||||||||
| PMID: | 16858628 | ||||||||||
| 5. | |||||||||||
| Journal: | J Nutr. 2006 Nov;136(11):2728-34. | ||||||||||
| Title: | Benzyl isothiocyanate-induced DNA damage causes G2/M cell cycle arrest and apoptosis in human pancreatic cancer cells. | ||||||||||
| Author: | Zhang, Ruifen|Loganathan, Sivakumar|Humphreys, Ian|Srivastava, Sanjay K | ||||||||||
| PMID: | 17056792 | ||||||||||
| 6. | |||||||||||
| Journal: | Clin Cancer Res. 2008 Apr 1;14(7):2042-8. | ||||||||||
| Title: | Single-nucleotide polymorphisms of DNA damage response genes are associated with overall survival in patients with pancreatic cancer. | ||||||||||
| Author: | Okazaki, Taro|Jiao, Li|Chang, Ping|Evans, Douglas B|Abbruzzese, James L|Li, Donghui | ||||||||||
| PMID: | 18381943 | ||||||||||
| 7. | |||||||||||
| Journal: | Pol Arch Med Wewn. 2008 Nov;118(11):645-9. | ||||||||||
| Title: | Is there any relationship between BRCA1 gene mutation and pancreatic cancer development? | ||||||||||
| Author: | Lawniczak, Malgorzata|Gawin, Alicja|Bialek, Andrzej|Lubinski, Jan|Starzynska, Teresa | ||||||||||
| PMID: | 19140568 | ||||||||||
| 8. | |||||||||||
| Journal: | Toxicol In Vitro. 2009 Apr;23(3):418-24. | ||||||||||
| Title: | Compound MMH01 possesses toxicity against human leukemia and pancreatic cancer cells. | ||||||||||
| Author: | Chen, Yu-Jen|Chou, Cheng-Jen|Chang, Tun-Tschu | ||||||||||
| PMID: | 19344682 | ||||||||||
| 9. | |||||||||||
| Journal: | Front Biosci (Elite Ed). 2009 Jun 1;1:568-76. | ||||||||||
| Title: | Benzyl isothiocyanate sensitizes human pancreatic cancer cells to radiation therapy. | ||||||||||
| Author: | Sahu, Ravi Prakash|Epperly, Michael Wayne|Srivastava, Sanjay Kumar | ||||||||||
| PMID: | 19482673 | ||||||||||
| 10. | |||||||||||
| Journal: | J Transl Med. 2009 Jun 11;7:43. | ||||||||||
| Title: | Synthetic lethal RNAi screening identifies sensitizing targets for gemcitabine therapy in pancreatic cancer. | ||||||||||
| Author: | Azorsa, David O|Gonzales, Irma M|Basu, Gargi D|Choudhary, Ashish|Arora, Shilpi|Bisanz, Kristen M|Kiefer, Jeffrey A|Henderson, Meredith C|Trent, Jeffrey M|Von Hoff, Daniel D|Mousses, Spyro | ||||||||||
| PMID: | 19519883 | ||||||||||
| 11. | |||||||||||
| Journal: | Cancer Epidemiol. 2010 Oct;34(5):656-8. | ||||||||||
| Title: | CHEK2 gene alterations in the forkhead-associated domain, 1100delC and del5395 do not modify the risk of sporadic pancreatic cancer. | ||||||||||
| Author: | Mohelnikova-Duchonova, Beatrice|Havranek, Ondrej|Hlavata, Ivona|Foretova, Lenka|Kleibl, Zdenek|Pohlreich, Petr|Soucek, Pavel | ||||||||||
| PMID: | 20643596 | ||||||||||
| 12. | |||||||||||
| Journal: | Clin Genet. 2010 Apr;77(4):333-41. | ||||||||||
| Title: | Clinical and genetic analysis of 18 pancreatic carcinoma/melanoma-prone families. | ||||||||||
| Author: | Bartsch, D K|Langer, P|Habbe, N|Matthai, E|Chaloupka, B|Sina, M|Hahn, S A|Slater, E P | ||||||||||
| PMID: | 20041885 | ||||||||||
| 13. | |||||||||||
| Journal: | Invest New Drugs. 2011 Jun;29(3):401-10. | ||||||||||
| Title: | Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation. | ||||||||||
| Author: | Hong, Bo|Lui, Vivian W Y|Hui, Edwin P|Ng, Margaret H L|Cheng, Suk-Hang|Sung, Fion L|Tsang, Chi-Man|Tsao, Sai-Wah|Chan, Anthony Tak-Cheung | ||||||||||
| PMID: | 20013349 | ||||||||||
| 14. | |||||||||||
| Journal: | Fam Cancer. 2011 Jun;10(2):323-30. | ||||||||||
| Title: | German national case collection for familial pancreatic cancer (FaPaCa): ten years experience. | ||||||||||
| Author: | Schneider, Ralph|Slater, Emily P|Sina, Mercede|Habbe, Nils|Fendrich, Volker|Matthai, Elvira|Langer, Peter|Bartsch, Detlef K | ||||||||||
| PMID: | 21207249 | ||||||||||
| 15. | |||||||||||
| Journal: | PLoS One. 2011 Feb 11;6(2):e16958. | ||||||||||
| Title: | RNA binding protein CUGBP2/CELF2 mediates curcumin-induced mitotic catastrophe of pancreatic cancer cells. | ||||||||||
| Author: | Subramaniam, Dharmalingam|Ramalingam, Satish|Linehan, David C|Dieckgraefe, Brian K|Postier, Russell G|Houchen, Courtney W|Jensen, Roy A|Anant, Shrikant | ||||||||||
| PMID: | 21347286 | ||||||||||
| 16. | |||||||||||
| Journal: | Hum Mol Genet. 2012 Nov 1;21(21):4615-27. | ||||||||||
| Title: | Hsp90 stabilizes Cdc25A and counteracts heat shock-mediated Cdc25A degradation and cell-cycle attenuation in pancreatic carcinoma cells. | ||||||||||
| Author: | Giessrigl, Benedikt|Krieger, Sigurd|Rosner, Margit|Huttary, Nicole|Saiko, Philipp|Alami, Mouad|Messaoudi, Samir|Peyrat, Jean-Francois|Maciuk, Alexandre|Gollinger, Michaela|Kopf, Sabine|Kazlauskas, Egidijus|Mazal, Peter|Szekeres, Thomas|Hengstschlager, Mar | ||||||||||
| PMID: | 22843495 | ||||||||||
| 17. | |||||||||||
| Journal: | J Cell Mol Med. 2013 Oct;17(10):1261-70. | ||||||||||
| Title: | Inhibition of checkpoint kinase 2 (CHK2) enhances sensitivity of pancreatic adenocarcinoma cells to gemcitabine. | ||||||||||
| Author: | Duong, Hong-Quan|Hong, Young Bin|Kim, Jung Soon|Lee, Hee-Seok|Yi, Yong Weon|Kim, Yeon Jeong|Wang, Antai|Zhao, Wenjing|Cho, Chi Heum|Seong, Yeon-Sun|Bae, Insoo | ||||||||||
| PMID: | 23855452 | ||||||||||
| 18. | |||||||||||
| Journal: | Invest New Drugs. 2013 Oct;31(5):1115-24. | ||||||||||
| Title: | Digalloylresveratrol, a novel resveratrol analog inhibits the growth of human pancreatic cancer cells. | ||||||||||
| Author: | Saiko, Philipp|Graser, Geraldine|Giessrigl, Benedikt|Steinmann, Marie-Therese|Schuster, Heike|Lackner, Andreas|Grusch, Michael|Krupitza, Georg|Jaeger, Walter|Somepalli, Venkateswarlu|Golakoti, Trimurtulu|Fritzer-Szekeres, Monika|Szekeres, Thomas | ||||||||||
| PMID: | 23943154 | ||||||||||
| 19. | |||||||||||
| Journal: | Oncogene. 2014 Nov 20;33(47):5450-6. | ||||||||||
| Title: | Low CHD5 expression activates the DNA damage response and predicts poor outcome in patients undergoing adjuvant therapy for resected pancreatic cancer. | ||||||||||
| Author: | Hall, W A|Petrova, A V|Colbert, L E|Hardy, C W|Fisher, S B|Saka, B|Shelton, J W|Warren, M D|Pantazides, B G|Gandhi, K|Kowalski, J|Kooby, D A|El-Rayes, B F|Staley, C A 3rd|Volkan Adsay, N|Curran, W J|Landry, J C|Maithel, S K|Yu, D S | ||||||||||
| PMID: | 24276239 | ||||||||||
| 20. | |||||||||||
| Journal: | Cancer Lett. 2014 Dec 28;355(2):297-309. | ||||||||||
| Title: | SKLB316, a novel small-molecule inhibitor of cell-cycle progression, induces G2/M phase arrest and apoptosis in vitro and inhibits tumor growth in vivo. | ||||||||||
| Author: | Xia, Yong|Lei, Qian|Zhu, Yongxia|Ye, Tinghong|Wang, Ningyu|Li, Guobo|Shi, Xuanhong|Liu, Yantong|Shao, Bin|Yin, Tao|Zhao, Lifeng|Wu, Wenshuang|Song, Xuejiao|Xiong, Ying|Wei, Yuquan|Yu, Luoting | ||||||||||
| PMID: | 25301449 | ||||||||||
| 21. | |||||||||||
| Journal: | Histochem Cell Biol. 2014 Dec;142(6):713-20. | ||||||||||
| Title: | Elevated DNA damage response in pancreatic cancer. | ||||||||||
| Author: | Osterman, Michael|Kathawa, Deion|Liu, Diangang|Guo, Huan|Zhang, Chao|Li, Mo|Yu, Xiaochun|Li, Fei | ||||||||||
| PMID: | 25002126 | ||||||||||
| 22. | |||||||||||
| Journal: | PLoS One. 2014 Feb 6;9(2):e88322. | ||||||||||
| Title: | Epicatechin stimulates mitochondrial activity and selectively sensitizes cancer cells to radiation. | ||||||||||
| Author: | Elbaz, Hosam A|Lee, Icksoo|Antwih, Deborah A|Liu, Jenney|Huttemann, Maik|Zielske, Steven P | ||||||||||
| PMID: | 24516636 | ||||||||||
| 23. | |||||||||||
| Journal: | Nutr Cancer. 2014;66(2):295-307. | ||||||||||
| Title: | Methylseleninic acid suppresses pancreatic cancer growth involving multiple pathways. | ||||||||||
| Author: | Wang, Lei|Hu, Hongbo|Wang, Zhe|Xiong, Hua|Cheng, Yan|Liao, Joshua Dezhong|Deng, Yibin|Lu, Junxuan | ||||||||||
| PMID: | 24447148 | ||||||||||
| 24. | |||||||||||
| Journal: | Endocr Relat Cancer. 2014 Feb 1;21(1):113-25. | ||||||||||
| Title: | Coupling G2/M arrest to the Wnt/beta-catenin pathway restrains pancreatic adenocarcinoma. | ||||||||||
| Author: | Sarkar, Sayantani|Mandal, Chandan|Sangwan, Rajender|Mandal, Chitra | ||||||||||
| PMID: | 24402132 | ||||||||||
| 25. | |||||||||||
| Journal: | Mol Pharmacol. 2014 Mar;85(3):408-19. | ||||||||||
| Title: | Phosphodiesterase 5 inhibitors enhance chemotherapy killing in gastrointestinal/genitourinary cancer cells. | ||||||||||
| Author: | Booth, Laurence|Roberts, Jane L|Cruickshanks, Nichola|Conley, Adam|Durrant, David E|Das, Anindita|Fisher, Paul B|Kukreja, Rakesh C|Grant, Steven|Poklepovic, Andrew|Dent, Paul | ||||||||||
| PMID: | 24353313 | ||||||||||
| 26. | |||||||||||
| Journal: | Cancer Epidemiol Biomarkers Prev. 2016 Jan;25(1):207-11. | ||||||||||
| Title: | Prevalence of Pathogenic Mutations in Cancer Predisposition Genes among Pancreatic Cancer Patients. | ||||||||||
| Author: | Hu, Chunling|Hart, Steven N|Bamlet, William R|Moore, Raymond M|Nandakumar, Kannabiran|Eckloff, Bruce W|Lee, Yean K|Petersen, Gloria M|McWilliams, Robert R|Couch, Fergus J | ||||||||||
| PMID: | 26483394 | ||||||||||
| 27. | |||||||||||
| Journal: | Cancer. 2016 Jan 15;122(2):304-11. | ||||||||||
| Title: | Inherited mutations in cancer susceptibility genes are common among survivors of breast cancer who develop therapy-related leukemia. | ||||||||||
| Author: | Churpek, Jane E|Marquez, Rafael|Neistadt, Barbara|Claussen, Kimberly|Lee, Ming K|Churpek, Matthew M|Huo, Dezheng|Weiner, Howard|Bannerjee, Mekhala|Godley, Lucy A|Le Beau, Michelle M|Pritchard, Colin C|Walsh, Tom|King, Mary-Claire|Olopade, Olufunmilayo I|L | ||||||||||
| PMID: | 26641009 | ||||||||||
| 28. | |||||||||||
| Journal: | Ann Surg Oncol. 2016 May;23(5):1729-35. | ||||||||||
| Title: | Statewide Retrospective Review of Familial Pancreatic Cancer in Delaware, and Frequency of Genetic Mutations in Pancreatic Cancer Kindreds. | ||||||||||
| Author: | Catts, Zohra Ali-Khan|Baig, Muhammad Khurram|Milewski, Becky|Keywan, Christine|Guarino, Michael|Petrelli, Nicholas | ||||||||||
| PMID: | 26727920 | ||||||||||
| 29. | |||||||||||
| Journal: | PLoS One. 2016 Mar 25;11(3):e0152280. | ||||||||||
| Title: | Phosphoproteome Analysis of Invasion and Metastasis-Related Factors in Pancreatic Cancer Cells. | ||||||||||
| Author: | Tan, Xiaodong|Liu, Peng|Huang, Yinpeng|Zhou, Lei|Yang, Yifan|Wang, Huaitao|Yu, Boqiang|Meng, Xiangli|Zhang, Xiaobo|Gao, Feng | ||||||||||
| PMID: | 27014871 | ||||||||||
| 30. | |||||||||||
| Journal: | Int J Cancer. 2016 Aug 1;139(3):601-6. | ||||||||||
| Title: | Do founder mutations characteristic of some cancer sites also predispose to pancreatic cancer? | ||||||||||
| Author: | Lener, Marcin R|Scott, Rodney J|Kluzniak, Wojciech|Baszuk, Piotr|Cybulski, Cezary|Wiechowska-Kozlowska, Anna|Huzarski, Tomasz|Byrski, Tomasz|Kladny, Jozef|Pietrzak, Sandra|Soluch, Agnieszka|Jakubowska, Anna|Lubinski, Jan | ||||||||||
| PMID: | 27038244 | ||||||||||
| 31. | |||||||||||
| Journal: | World J Gastroenterol. 2016 Aug 28;22(32):7275-88. | ||||||||||
| Title: | Perspectives on the combination of radiotherapy and targeted therapy with DNA repair inhibitors in the treatment of pancreatic cancer. | ||||||||||
| Author: | Yang, Shih-Hung|Kuo, Ting-Chun|Wu, Hsu|Guo, Jhe-Cyuan|Hsu, Chiun|Hsu, Chih-Hung|Tien, Yu-Wen|Yeh, Kun-Huei|Cheng, Ann-Lii|Kuo, Sung-Hsin | ||||||||||
| PMID: | 27621574 | ||||||||||
| 32. | |||||||||||
| Journal: | Cancer Res Treat. 2017 Apr;49(2):430-436. | ||||||||||
| Title: | The Prevalence of Founder Mutations among Individuals from Families with Familial Pancreatic Cancer Syndrome. | ||||||||||
| Author: | Lener, Marcin R|Kashyap, Aniruddh|Kluzniak, Wojciech|Cybulski, Cezary|Soluch, Agnieszka|Pietrzak, Sandra|Huzarski, Tomasz|Gronwald, Jacek|Lubinski, Jan | ||||||||||
| PMID: | 27488870 | ||||||||||
| 33. | |||||||||||
| Journal: | Genet Med. 2018 Jan;20(1):119-127. | ||||||||||
| Title: | Prevalence of germ-line mutations in cancer genes among pancreatic cancer patients with a positive family history. | ||||||||||
| Author: | Chaffee, Kari G|Oberg, Ann L|McWilliams, Robert R|Majithia, Neil|Allen, Brian A|Kidd, John|Singh, Nanda|Hartman, Anne-Renee|Wenstrup, Richard J|Petersen, Gloria M | ||||||||||
| PMID: | 28726808 | ||||||||||
| 34. | |||||||||||
| Journal: | J Gastroenterol. 2018 Oct;53(10):1159-1167. | ||||||||||
| Title: | Germline variants in pancreatic cancer patients with a personal or family history of cancer fulfilling the revised Bethesda guidelines. | ||||||||||
| Author: | Ohmoto, Akihiro|Morizane, Chigusa|Kubo, Emi|Takai, Erina|Hosoi, Hiroko|Sakamoto, Yasunari|Kondo, Shunsuke|Ueno, Hideki|Shimada, Kazuaki|Yachida, Shinichi|Okusaka, Takuji | ||||||||||
| PMID: | 29667044 | ||||||||||
| 35. | |||||||||||
| Journal: | Oncotarget. 2018 Apr 13;9(28):19817-19825. | ||||||||||
| Title: | Association between homologous recombination repair gene mutations and response to oxaliplatin in pancreatic cancer. | ||||||||||
| Author: | Kondo, Tomohiro|Kanai, Masashi|Kou, Tadayuki|Sakuma, Tomohiro|Mochizuki, Hiroaki|Kamada, Mayumi|Nakatsui, Masahiko|Uza, Norimitsu|Kodama, Yuzo|Masui, Toshihiko|Takaori, Kyoichi|Matsumoto, Shigemi|Miyake, Hidehiko|Okuno, Yasushi|Muto, Manabu | ||||||||||
| PMID: | 29731985 | ||||||||||
| 36. | |||||||||||
| Journal: | Genet Med. 2018 Jul 2. pii: 10.1038/s41436-018-0009-5. | ||||||||||
| Title: | Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer. | ||||||||||
| Author: | Yurgelun, Matthew B|Chittenden, Anu B|Morales-Oyarvide, Vicente|Rubinson, Douglas A|Dunne, Richard F|Kozak, Margaret M|Qian, Zhi Rong|Welch, Marisa W|Brais, Lauren K|Da Silva, Annacarolina|Bui, Justin L|Yuan, Chen|Li, Tingting|Li, Wanwan|Masuda, Atsuhiro| | ||||||||||
| PMID: | 29961768 | ||||||||||
| 37. | |||||||||||
| Journal: | Pancreas. 2018 Sep;47(8):924-936. | ||||||||||
| Title: | Germline Variants and Risk for Pancreatic Cancer: A Systematic Review and Emerging Concepts. | ||||||||||
| Author: | Zhan, Wei|Shelton, Celeste A|Greer, Phil J|Brand, Randall E|Whitcomb, David C | ||||||||||
| PMID: | 30113427 | ||||||||||