Primary Site >> Stomach Cancer

Gene >> CHEK2

Journal: Jpn J Cancer Res. 2000 Sep;91(9):875-9.
Title: Absence of germline CHK2 mutations in familial gastric cancer.
Author: Kimura, K|Shinmura, K|Yoshimura, K|Shimizu, K|Katai, H|Beppu, Y|Moriya, H|Yokota, J
PMID: 11011113
Journal: Breast Cancer Res. 2002;4(3):R4. Epub 2002 Mar 20.
Title: Mutation analysis of the CHK2 gene in breast carcinoma and other cancers.
Author: Ingvarsson, Sigurdur|Sigbjornsdottir, Bjarnveig I|Huiping, Chen|Hafsteinsdottir, Sigridur H|Ragnarsson, Gisli|Barkardottir, Rosa B|Arason, Adalgeir|Egilsson, Valgardur|Bergthorsson, Jon T H
PMID: 12052256
Journal: Oncogene. 2007 Nov 15;26(52):7371-9. Epub 2007 May 21.
Title: Identification and characterization of a novel p42.3 gene as tumor-specific and mitosis phase-dependent expression in gastric cancer.
Author: Xu, X|Li, W|Fan, X|Liang, Y|Zhao, M|Zhang, J|Liang, Y|Tong, W|Wang, J|Yang, W|Lu, Y
PMID: 17525738
Journal: Pathol Int. 2007 Sep;57(9):566-71.
Title: Increased wild-type p53-induced phosphatase 1 (Wip1 or PPM1D) expression correlated with downregulation of checkpoint kinase 2 in human gastric carcinoma.
Author: Fuku, Takeichi|Semba, Shuho|Yutori, Hirokazu|Yokozaki, Hiroshi
PMID: 17685927
Journal: Cancer Sci. 2008 Nov;99(11):2302-8.
Title: Synergistic interaction between trifluorothymidine and docetaxel is sequence dependent.
Author: Bijnsdorp, I V|Kruyt, F A|Gokoel, S|Fukushima, M|Peters, G J
PMID: 18957056
Journal: Braz J Med Biol Res. 2010 Mar;43(3):271-8.
Title: Growth inhibitory effect and Chk1-dependent signaling involved in G2/M arrest on human gastric cancer cells induced by diallyl disulfide.
Author: Ling, H|Wen, L|Ji, X X|Tang, Y L|He, J|Tan, H|Xia, H|Zhou, J G|Su, Q
PMID: 20401435
Journal: Planta Med. 2012 Jun;78(9):890-5.
Title: Xanthatin induces G2/M cell cycle arrest and apoptosis in human gastric carcinoma MKN-45 cells.
Author: Zhang, Lei|Tao, Li|Ruan, Junshan|Li, Weidong|Wu, Yu|Yan, Linggeng|Zhang, Feng|Fan, Fangtian|Zheng, Shizhong|Wang, Aiyun|Lu, Yin
PMID: 22532019
Journal: Apoptosis. 2013 Mar;18(3):347-60.
Title: Targeting Chk2 improves gastric cancer chemotherapy by impairing DNA damage repair.
Author: Gutierrez-Gonzalez, A|Belda-Iniesta, C|Bargiela-Iparraguirre, J|Dominguez, G|Garcia Alfonso, P|Perona, R|Sanchez-Perez, I
PMID: 23271172
Journal: Fam Cancer. 2013 Sep;12(3):473-8.
Title: The risk of gastric cancer in carriers of CHEK2 mutations.
Author: Teodorczyk, Urszula|Cybulski, Cezary|Wokolorczyk, Dominika|Jakubowska, Anna|Starzynska, Teresa|Lawniczak, Malgorzata|Domagala, Pawel|Ferenc, Katarzyna|Marlicz, Krzysztof|Banaszkiewicz, Zbigniew|Wisniowski, Rafal|Narod, Steven A|Lubinski, Jan
PMID: 23296741
Journal: Carcinogenesis. 2013 Jul;34(7):1536-42.
Title: Genetic variants in DNA repair pathway genes and risk of esophageal squamous cell carcinoma and gastric adenocarcinoma in a Chinese population.
Author: Li, Wen-Qing|Hu, Nan|Hyland, Paula L|Gao, Ying|Wang, Zhao-Ming|Yu, Kai|Su, Hua|Wang, Chao-Yu|Wang, Le-Min|Chanock, Stephen J|Burdett, Laurie|Ding, Ti|Qiao, You-Lin|Fan, Jin-Hu|Wang, Yuan|Xu, Yi|Shi, Jian-Xin|Gu, Fangyi|Wheeler, William|Xiong, Xiao-Qin|Gif
PMID: 23504502
Journal: Oncol Rep. 2014 Nov;32(5):2274-82.
Title: Diallyl disulfide selectively causes checkpoint kinase-1 mediated G2/M arrest in human MGC803 gastric cancer cell line.
Author: Ling, Hui|Lu, Li-Feng|He, Jie|Xiao, Guo-Hua|Jiang, Hao|Su, Qi
PMID: 25176258
Journal: Food Chem Toxicol. 2014 Jun;68:61-70.
Title: Chk1, but not Chk2, is responsible for G2/M phase arrest induced by diallyl disulfide in human gastric cancer BGC823 cells.
Author: Bo, Su|Hui, He|Li, Wang|Hui, Ling|Hong, Xia|Lin, Dong|Dai, Wen-Xiang|Wu, You-Hua|Ai, Xiao-Hong|Hao, Jiang|Qi, Su
PMID: 24650757
Journal: PLoS One. 2014 Mar 18;9(3):e90793.
Title: Antitumor activity of di-n-butyl-(2,6-difluorobenzohydroxamato)tin(IV) against human gastric carcinoma SGC-7901 cells via G2/M cell cycle arrest and cell apoptosis.
Author: Yunlan, Li|Juan, Zheng|Qingshan, Li
PMID: 24643073
Journal: Pathobiology. 2014;81(1):25-35.
Title: DNA damage response-related proteins in gastric cancer: ATM, Chk2 and p53 expression and their prognostic value.
Author: Lee, Hee Eun|Han, Nayoung|Kim, Min A|Lee, Hye Seung|Yang, Han-Kwang|Lee, Byung Lan|Kim, Woo Ho
PMID: 23969480
Journal: Cancer Res. 2016 Apr 1;76(7):1714-23.
Title: Genomic Landscape of Somatic Alterations in Esophageal Squamous Cell Carcinoma and Gastric Cancer.
Author: Hu, Nan|Kadota, Mitsutaka|Liu, Huaitian|Abnet, Christian C|Su, Hua|Wu, Hailong|Freedman, Neal D|Yang, Howard H|Wang, Chaoyu|Yan, Chunhua|Wang, Lemin|Gere, Sheryl|Hutchinson, Amy|Song, Guohong|Wang, Yuan|Ding, Ti|Qiao, You-Lin|Koshiol, Jill|Dawsey, Sanford
PMID: 26857264
Journal: J Clin Oncol. 2016 Apr 10;34(11):1208-16.
Title: Increased Risk for Other Cancers in Addition to Breast Cancer for CHEK2*1100delC Heterozygotes Estimated From the Copenhagen General Population Study.
Author: Naslund-Koch, Charlotte|Nordestgaard, Borge G|Bojesen, Stig E
PMID: 26884562
Journal: Zhonghua Zhong Liu Za Zhi. 2016 Apr;38(4):258-62.
Title: [Jaridonin, a new diterpenoid from Isodon rubescens, induces cell cycle arrest in gastric cancer cells through activating ataxia telangiectasia mutated kinase].
Author: Ma, Y C|Su, N|Zhao, N M|Li, Q Y|Zhang, M|Zhao, H W|Liu, H M|Qin, Y H
PMID: 27087371
Journal: Biochem J. 2016 Jul 15;473(14):2131-9.
Title: miR-30a can inhibit DNA replication by targeting RPA1 thus slowing cancer cell proliferation.
Author: Zou, Zhenyou|Ni, Mengjie|Zhang, Jing|Chen, Yongfeng|Ma, Hongyu|Qian, Shihan|Tang, Longhua|Tang, Jiamei|Yao, Hailun|Zhao, Chengbin|Lu, Xiongwen|Sun, Hongyang|Qian, Jue|Mao, Xiaoting|Lu, Xulin|Liu, Qun|Zen, Juping|Wu, Hanbing|Bao, Zhaosheng|Lin, Shudan|Shen
PMID: 27208176
Journal: Mol Cancer Ther. 2017 Apr;16(4):566-577.
Title: AZD6738, A Novel Oral Inhibitor of ATR, Induces Synthetic Lethality with ATM Deficiency in Gastric Cancer Cells.
Author: Min, Ahrum|Im, Seock-Ah|Jang, Hyemin|Kim, Seongyeong|Lee, Miso|Kim, Debora Keunyoung|Yang, Yaewon|Kim, Hee-Jun|Lee, Kyung-Hun|Kim, Jin Won|Kim, Tae-Yong|Oh, Do-Youn|Brown, Jeff|Lau, Alan|O'Connor, Mark J|Bang, Yung-Jue
PMID: 28138034
Journal: Int J Cancer. 2017 Jun 1;140(11):2587-2595.
Title: DNA damage repair and survival outcomes in advanced gastric cancer patients treated with first-line chemotherapy.
Author: Ronchetti, Livia|Melucci, Elisa|De Nicola, Francesca|Goeman, Frauke|Casini, Beatrice|Sperati, Francesca|Pallocca, Matteo|Terrenato, Irene|Pizzuti, Laura|Vici, Patrizia|Sergi, Domenico|Di Lauro, Luigi|Amoreo, Carla Azzurra|Gallo, Enzo|Diodoro, Maria Grazia
PMID: 28233295
Journal: Biomed Pharmacother. 2017 May;89:772-780.
Title: Effect of diterpenoid kaurenoic acid on genotoxicity and cell cycle progression in gastric cancer cell lines.
Author: Cardoso, Plinio Cerqueira Dos Santos|Rocha, Carlos Alberto Machado da|Leal, Mariana Ferreira|Bahia, Marcelo de Oliveira|Alcantara, Diego Di Felipe Avila|Santos, Raquel Alves Dos|Goncalves, Natalia Dos Santos|Ambrosio, Sergio Ricardo|Cavalcanti, Bruno Coel
PMID: 28273639
Journal: Mol Med Rep. 2017 Oct;16(4):4287-4292.
Title: Associations between mutations of the cell cycle checkpoint kinase 2 gene and gastric carcinogenesis.
Author: Hong, Yan|Shi, Jun|Ge, Zhijun|Wu, Haorong
PMID: 29067458
Journal: Biomed Pharmacother. 2018 Feb;98:694-700.
Title: FPHPB inhibits gastric tumor cell proliferation by inducing G2-M cell cycle arrest.
Author: Xue, Lei|Wu, Zhijun|Liu, Jinyuan|Luo, Jinhua
PMID: 29304495
Journal: Int J Oncol. 2018 Mar;52(3):978-988.
Title: Expression of DNA damage response proteins in gastric cancer: Comprehensive protein profiling and histological analysis.
Author: Arai, Hiroki|Wada, Ryuichi|Ishino, Kousuke|Kudo, Mitsuhiro|Uchida, Eiji|Naito, Zenya
PMID: 29328366
Journal: Ecancermedicalscience. 2018 Jan 30;12:804.
Title: Men seeking counselling in a Breast Cancer Risk Evaluation Clinic.
Author: Freitas, Ana Catarina|Opiniao, Ana|Fragoso, Sofia|Nunes, Hugo|Santos, Madalena|Clara, Ana|Bento, Sandra|Luis, Ana|Silva, Jorge|Moura, Cecilia|Filipe, Bruno|Machado, Patricia|Santos, Sidonia|Andre, Saudade|Rodrigues, Paula|Parreira, Joana|Vaz, Fatima
PMID: 29456621
Journal: Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F469-F478.
Title: Protective effect of the BET protein inhibitor JQ1 in cisplatin-induced nephrotoxicity.
Author: Sun, Liping|Liu, Jing|Yuan, Yanggang|Zhang, Xinzhou|Dong, Zheng
PMID: 29767555